FAM19471-i1-1.1_001150

Annotations

Type	Name	Description	Pathways
KEGG reaction	R08240	6-thioinosine 5'-monophosphate:NAD+ oxidoreductase; 6-Thioinosine-5'-monophosphate + NAD+ + H2O <=> 6-Thioxanthine 5'-monophosphate + NADH + H+	kornec00983
KEGG reaction	R01134	inosine-5'-phosphate:NADP+ oxidoreductase (aminating); NADH:guanosine-5'-phosphate oxidoreductase (deaminating); IMP + Ammonia + NADP+ <=> GMP + NADPH + H+	kornec01100 kornec00230
KEGG reaction	R01130	IMP:NAD+ oxidoreductase; IMP + NAD+ + H2O <=> Xanthosine 5'-phosphate + NADH + H+	kornec01100 kornec00230 kornec01110
Ortholog	N0.HOG0001401	GMP reductase
KEGG gene	K00364	E1.7.1.7, guaC; GMP reductase [EC:1.7.1.7]	kornec01100 kornec00230
KEGG gene	K00088	IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205]	kornec01100 kornec00230 kornec00983 kornec01110
Gene Product	GMP reductase
Eggnog Protein	EP:guaC
Eggnog Ortholog	EO:1TNYF
Eggnog Description	ED:Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase
EC Number	EC:1.7.1.7	GMP reductase; guanosine 5'-monophosphate reductase; NADPH:GMP oxidoreductase (deaminating); guanosine monophosphate reductase; guanylate reductase; NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating); guanosine 5'-phosphate reductase	kornec01100 kornec00230
EC Number	EC:1.1.1.205	IMP dehydrogenase; inosine-5'-phosphate dehydrogenase; inosinic acid dehydrogenase; inosinate dehydrogenase; inosine 5'-monophosphate dehydrogenase; inosine monophosphate dehydrogenase; IMP oxidoreductase; inosine monophosphate oxidoreductase	kornec01100 kornec00230 kornec00983 kornec01110

Pathway	Description
kornec00230	Purine metabolism
kornec00983	Drug metabolism - other enzymes
kornec01100	Metabolic pathways
kornec01110	Biosynthesis of secondary metabolites

Sequences

Nucleotide sequence (GC-content: 55.4 %):

ATGGAAACTTTTGATTATGATGACATTCAACTGATCCCTAACAAGTGTGTGATCAAGAGCAGAAAGGAAGCTGACCCGCAGGTTAAATTTGGTCCCAAAACCTTCAAGATTCCCGTTGTACCGGCTAACATGGCCTCGGTAATCAACGAAGAATTGGCGGTCTGGTTAGCCCAAAATGACTACTACTACGTCATGCACCGTTTCAACCCCGCGGACCGGGCCGGCTTCGTTAAGCGAATGCACGACCGGGGGCTGTTTGCCTCGATTTCCGTCGGGATCAAGGACAGCGAGTATGACTTTATCAATCAACTAAAAGACGAACAATTGGTGCCGGAGTACATCACGATCGACGTTGCCCATGGACATTCTGATTTCGTGATCGCCATGATTAAACACATCAAGCAACAACTGCCGACCACCTTCTTAACCGCCGGTAACGTGGCCACCCCGGAGGCCGTTCGCGACCTGGAAAACGCCGGCGCCGACGCCACCAAGGTCGGAGTGGGCCCCGGTAAGGCTTGCATCACCAAGCTCAAGACCGGTTTCGGGACCGGGGGCTGGCAACTCGCCGCCCTGCGCCTGTGTTCCAAGGCCGCCCGCAAGCCATTAATCGCCGACGGGGGAATCCGCCACAACGGCGACATCGCCAAGTCCGTTCGCTTCGGGGCCTCAATGGTGATGATTGGCTCGCTGTTGGCCGGCCACCAAGAATCCCCGGGCAACCTGATCACGATTGACGGCAAGCGCTACAAGCAATACTGGGGCTCGGCCTCCGAAGTCCAAAAGGGCGCCTACCGCAACGTCGAAGGTAAGCAAATGCTGGTGCCGTTCCGGGGTGCCATCGAAGACACCCTGGTGGAGATGGAAGAAGACCTCCAGTCAGCGATTTCTTACGCCGGTGGGCGCGACCTGGAATCGATCACCAAAGTCGACTACGTTATCGTTAAAAACTCAATTTTAAACGGGGACTACTAG

Protein sequence:

METFDYDDIQLIPNKCVIKSRKEADPQVKFGPKTFKIPVVPANMASVINEELAVWLAQNDYYYVMHRFNPADRAGFVKRMHDRGLFASISVGIKDSEYDFINQLKDEQLVPEYITIDVAHGHSDFVIAMIKHIKQQLPTTFLTAGNVATPEAVRDLENAGADATKVGVGPGKACITKLKTGFGTGGWQLAALRLCSKAARKPLIADGGIRHNGDIAKSVRFGASMVMIGSLLAGHQESPGNLITIDGKRYKQYWGSASEVQKGAYRNVEGKQMLVPFRGAIEDTLVEMEEDLQSAISYAGGRDLESITKVDYVIVKNSILNGDY

GenBank Info

locus_tag - FAM19471-i1-1.1_001150
EC_number - 1.7.1.7
inference - COORDINATES: similar to AA sequence:RefSeq:WP_003711676.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - GMP reductase
protein_id - extdb:FAM19471-i1-1.1_001150

Annotations

Occurs in the following pathway maps:

Sequences

GenBank Info

Gene locus (click to toggle display options)