locus tag: FAM19471-i1-1.1_000885 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
Gene Product
 alpha-ketoacid dehydrogenase subunit beta
KEGG reaction
 R03270 2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate kornec00010 kornec00620 kornec00020
KEGG reaction
 R01699 pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating); Pyruvate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2
KEGG reaction
 R00209 pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex; Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+ kornec01200 kornec01100 kornec01110 kornec01120
KEGG reaction
 R00014 pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating); Pyruvate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + CO2 kornec00010 kornec00620 kornec00020
Ortholog
 N0.HOG0000682 alpha-ketoacid dehydrogenase subunit beta
KEGG gene
 K21417 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-]
KEGG gene
 K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1] kornec00010 kornec05230 kornec01200 kornec01100 kornec00620 kornec04066 kornec01110 kornec01120 kornec00020 kornec04922
Gene Ontology
 GO:0140032 glycosylation-dependent protein binding
Gene Ontology
 GO:0140030 modification-dependent protein binding
Gene Ontology
 GO:0071944 cell periphery
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0030312 external encapsulating structure
Gene Ontology
 GO:0016020 membrane
Gene Ontology
 GO:0005886 plasma membrane
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005618 cell wall
Gene Ontology
 GO:0005575 cellular_component
Gene Ontology
 GO:0005515 protein binding
Gene Ontology
 GO:0005488 binding
Gene Ontology
 GO:0003674 molecular_function
Eggnog Protein
 EP:pdhB
Eggnog Ortholog
 EO:1TP3J
Eggnog Description
 ED:Transketolase
EC Number
 EC:1.2.4.1 pyruvate dehydrogenase (acetyl-transferring); pyruvate decarboxylase (ambiguous); pyruvate dehydrogenase (ambiguous); pyruvate dehydrogenase (lipoamide); pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating); pyruvic acid dehydrogenase; pyruvic dehydrogenase (ambiguous) kornec00010 kornec01100 kornec00620 kornec01110 kornec01120 kornec00020

Occurs in the following pathway maps:

Pathway Description
kornec00010 Glycolysis / Gluconeogenesis
kornec00020 Citrate cycle (TCA cycle)
kornec00620 Pyruvate metabolism
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01120 Microbial metabolism in diverse environments
kornec01200 Carbon metabolism
kornec04066 HIF-1 signaling pathway
kornec04922 Glucagon signaling pathway
kornec05230 Central carbon metabolism in cancer

Sequences

Nucleotide sequence (GC-content: 51.2 %):

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ATGGCTAAGATTACGATGATTAAGGCGGTCACGGACGCCCTCGATGAAGAATTAGCTCGTGACGAAAAAGTTCTTGTCTTTGGTGAAGACGTTGGTAACAACGGTGGGGTTTTCCGTGCCACTGAAGGCCTCCAAGCTAAGTACGGCGACAAGCGTGTCTTCGATACTCCATTAGCTGAATCCGGGATCATCGGTTTAGCTAACGGGCTTGCCACCCAAGGTTGGCGCCCAGTTCCAGAAATCCAATTCATGGGCTTCATCATGGAAGCCTTTGACGAAATTGCTGGTCAAATGGCTCGTCAACGCTTCCGTCACGCAGGTTCTCGTAAGGCTCCGATCACCATCCGTTCACCATTTGGTGGTGGTGTTCACGCCATCGAACTGCACTCCGACAACCTGGAAGGGTTAGTGGCCCAAGTTCCTGGTCTGCGGGTAGTTATTCCTTCTGACCCGTACGACGCTAAGGGGCTCCTTGCTTCCTCCATTCGTTCCGATGACCCAGTTTTCTTCCTGGAACACATGCGGGTTTATCGTTCCTTCCGTCAAGAAGTTCCGGACGAATCATACACTGTTCCGTTGGACAAGGCTGCCGTTAAGCGTGAAGGTTCTGACGTTACCATCATTTCCTACGGTTACATGGTTCGCGAAAGCTTAAACGCCGCTGAAGACCTGGCTAAGGAAGGCATCAACGCCGAAGTTCTTGACCTTCGTACTGTTTCCCCACTTGACGAAGAAACGATCTTAAACGAAGTTAAGAAGACCGGTCGTGTGGTTCTGGTTCAAGAAGCACAAAAGCAAGCTGGTGTAATGGGCTCCGTTGCTGCCTTGATTGCAGAAGACGCAATCCTTTCCCTGGAAGCACCAATTGCCCGTGTTTCCGCACCGGATACCCCTTACCCATGCAGTGACGCCGAAGGTGCTTGGCTTCCAAACAAGGACGACATCATCGCCGCTGTTAAGAAGACCGTTAATTTCTAG

Protein sequence:

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MAKITMIKAVTDALDEELARDEKVLVFGEDVGNNGGVFRATEGLQAKYGDKRVFDTPLAESGIIGLANGLATQGWRPVPEIQFMGFIMEAFDEIAGQMARQRFRHAGSRKAPITIRSPFGGGVHAIELHSDNLEGLVAQVPGLRVVIPSDPYDAKGLLASSIRSDDPVFFLEHMRVYRSFRQEVPDESYTVPLDKAAVKREGSDVTIISYGYMVRESLNAAEDLAKEGINAEVLDLRTVSPLDEETILNEVKKTGRVVLVQEAQKQAGVMGSVAALIAEDAILSLEAPIARVSAPDTPYPCSDAEGAWLPNKDDIIAAVKKTVNF

GenBank Info

locus_tag - FAM19471-i1-1.1_000885
inference - COORDINATES: similar to AA sequence:RefSeq:WP_017867715.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - alpha-ketoacid dehydrogenase subunit beta
protein_id - extdb:FAM19471-i1-1.1_000885

Gene locus (click to toggle display options) expand

Located on scaffold FAM19471-i1-1_scf0013

Update range to 10000 bp

Cellular location expand

Responsible annotations:
SL-0041: GO:0005618 cell wall
SL-0162: GO:0016020 membrane
SL-0039: GO:0005886 plasma membrane
FAM19471-i1-1.1_000884
FAM19471-i1-1.1_000886