locus tag: FAM19471-i1-1.1_001071 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
KEGG reaction
 R04946 O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine); O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate kornec01100 kornec00450
KEGG reaction
 R04945 O-Acetylhomoserine succinate-lyase (adding cysteine); O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
KEGG reaction
 R04944 O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine); O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate kornec01100 kornec00450
KEGG reaction
 R04941 Selenocystathionine L-homocysteine-lyase (deaminating); L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate kornec01100 kornec00450
KEGG reaction
 R03260 O-Succinyl-L-homoserine succinate-lyase (adding cysteine); O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate kornec01230 kornec01100 kornec00270 kornec01110
KEGG reaction
 R03217 O-Acetyl-L-homoserine succinate-lyase (adding cysteine); O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate kornec01100 kornec00270
KEGG reaction
 R02508 Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
KEGG reaction
 R02408 L-cystine thiocysteine-lyase (deaminating; pyruvate-forming); L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine kornec01100 kornec00270
KEGG reaction
 R01288 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide); O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate kornec00920 kornec01100 kornec00270
KEGG reaction
 R01286 L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming); L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate kornec01230 kornec01100 kornec00270 kornec01110
KEGG reaction
 R01283 L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming); L-Homocysteine + H2O <=> Hydrogen sulfide + Ammonia + 2-Oxobutanoate kornec00920 kornec01100
KEGG reaction
 R01001 L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming); L-Cystathionine + H2O <=> L-Cysteine + Ammonia + 2-Oxobutanoate kornec01230 kornec01100 kornec00260 kornec00270 kornec01110
KEGG reaction
 R00999 O-Succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming); O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia kornec01100 kornec00270
KEGG reaction
 R00782 L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming); L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia kornec01100 kornec00270
Gene Product
 PLP-dependent transferase
Ortholog
 N0.HOG0000392 aminotransferase class V-fold PLP-dependent enzyme
KEGG gene
 K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2] kornec00920 kornec01230 kornec01100 kornec00260 kornec00270 kornec01110
KEGG gene
 K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] kornec01230 kornec01100 kornec00270 kornec00450 kornec01110
KEGG gene
 K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] kornec00920 kornec01230 kornec01100 kornec00270 kornec00450 kornec01110
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0044424 obsolete intracellular part
Gene Ontology
 GO:0005737 cytoplasm
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005622 intracellular anatomical structure
Gene Ontology
 GO:0005575 cellular_component
Eggnog Protein
 EP:metC
Eggnog Ortholog
 EO:1TPC7
Eggnog Description
 ED:cystathionine
EC Number
 EC:4.4.1.8 Transferred to 4.4.1.13
EC Number
 EC:4.4.1.2 homocysteine desulfhydrase; homocysteine desulfurase; L-homocysteine hydrogen-sulfide-lyase (deaminating) kornec00920 kornec01100
EC Number
 EC:4.4.1.1 cystathionine gamma-lyase; homoserine deaminase; homoserine dehydratase; cystine desulfhydrase; cysteine desulfhydrase; gamma-cystathionase; cystathionase; homoserine deaminase-cystathionase; gamma-CTL; cystalysin; cysteine lyase; L-cystathionine cysteine-lyase (deaminating); CGL kornec01100 kornec00260 kornec00270 kornec00450 kornec01110
EC Number
 EC:2.5.1.48 cystathionine gamma-synthase; O-succinyl-L-homoserine succinate-lyase (adding cysteine); O-succinylhomoserine (thiol)-lyase; homoserine O-transsuccinylase (ambiguous); O-succinylhomoserine synthase; O-succinylhomoserine synthetase; cystathionine synthase; cystathionine synthetase; homoserine transsuccinylase (ambiguous); 4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase kornec00920 kornec01100 kornec00270 kornec00450 kornec01110

Occurs in the following pathway maps:

Pathway Description
kornec00260 Glycine, serine and threonine metabolism
kornec00270 Cysteine and methionine metabolism
kornec00450 Selenocompound metabolism
kornec00920 Sulfur metabolism
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01230 Biosynthesis of amino acids

Sequences

Nucleotide sequence (GC-content: 56.8 %):

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ATGAAGTTTAATACCCAATTAATTCACGGCGGCATTAGCGAAGACCCAACCACCGGGGCGGTTTCGACCCCAATTTACCGCTCCTCAACCTTCCGTCAACACGTCCTCGGCGGTGGCACCAAGTGGGAATATGCCCGGACCGGCAACCCGACCCGTGCCTCCTTGGAACTCTTAATGGCCCAACTAGAAGAAGGGGTCGCTGGCTTCGCCTTTGCCTCGGGATCGGCTGCCATCCACGCCGTCTTTTCCCTCTACTCCTCCGGCGATCACTTCATCGTTGGTAAGGACGTCTACGGGGGGACCTTCCGTTTGATCAACAAGGTCCTGAAGCGTTTCGGCCTCGAATTTACGGTTGTCGACACCCAGGACCTAGCGGCGGTCGAAGCGGCCGTGCAGGACAACACGGTGGCCATTTACTTTGAAACACCCACCAACCCGCTCTTGGAGGTTTCAGATATCGAAGCGATTGCTAAGATCGCCAAGAAGCATGGCTTAAAGACGGTCATTGATAACACCTTTGCCACGCCGTATAACCAACGCCCGCTGACCCTGGGCGCCGACATTGTAGTTCACTCCGCCACCAAGTACCTGGGCGGTCACTCCGACGTGGTGGGGGGGATTGCCGTTACGAACGACGAGGAAATTGCCGAACAGTTGGCCTTCATCCAAAACTCAATTGGCGCTGTCCTTGGGCCCGATGACTCCTGGCTTCTGATGCGGGGGATTAAGACCCTCGGCGCCCGAATGCGGATCCACCATGAAAACACCGCAGCCGTCATTGAACTGTTGGAAAAGGACCCGCGGGTTGCTCGGGTACTGTACCCGGGGCTGCCAGATTTCCCGGGACATGATATCGCGGCTAAGCAAATGGACCACTTCGGCGCCATGGTGTCCTTTGAACTGCAAGCGGGGCTCTCGGCAAAGAAGTTTGTCGAAAGCCTGCAGGTGATCACGCTGGCCGAAAGCCTCGGTGGGATCGAGAGCCTGATTGAAGTGCCGGCGGTGATGACCCACGGTTCCATTCCGCGTGAGGTCCGCCTGCAAAACGGGATTAAGGACGAATTAATCCGCTTGTCGGTTGGGATCGAAGACGAAGAAGACCTCGTGGCAGACTTACAGCAAGCCCTGGACCAACTGTCATAA

Protein sequence:

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MKFNTQLIHGGISEDPTTGAVSTPIYRSSTFRQHVLGGGTKWEYARTGNPTRASLELLMAQLEEGVAGFAFASGSAAIHAVFSLYSSGDHFIVGKDVYGGTFRLINKVLKRFGLEFTVVDTQDLAAVEAAVQDNTVAIYFETPTNPLLEVSDIEAIAKIAKKHGLKTVIDNTFATPYNQRPLTLGADIVVHSATKYLGGHSDVVGGIAVTNDEEIAEQLAFIQNSIGAVLGPDDSWLLMRGIKTLGARMRIHHENTAAVIELLEKDPRVARVLYPGLPDFPGHDIAAKQMDHFGAMVSFELQAGLSAKKFVESLQVITLAESLGGIESLIEVPAVMTHGSIPREVRLQNGIKDELIRLSVGIEDEEDLVADLQQALDQLS

GenBank Info

locus_tag - FAM19471-i1-1.1_001071
inference - COORDINATES: similar to AA sequence:RefSeq:WP_003682998.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - PLP-dependent transferase
protein_id - extdb:FAM19471-i1-1.1_001071

Gene locus (click to toggle display options) expand

Located on scaffold FAM19471-i1-1_scf0018

Update range to 10000 bp

Cellular location expand

Responsible annotations:
SL-0229: GO:0005622 intracellular anatomical structure
SL-0086: GO:0005737 cytoplasm
FAM19471-i1-1.1_001070
FAM19471-i1-1.1_001072