locus tag: FAM19471-i1-1.1_000965 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
KEGG reaction
 R00115 glutathione:NADP+ oxidoreductase; 2 Glutathione + NADP+ <=> Glutathione disulfide + NADPH + H+ kornec01100 kornec00480
KEGG reaction
 R00094 glutathione:NAD+ oxidoreductase; 2 Glutathione + NAD+ <=> Glutathione disulfide + NADH + H+
Ortholog
 N0.HOG0000697 FAD-dependent oxidoreductase
KEGG gene
 K21739 rclA; probable pyridine nucleotide-disulfide oxidoreductase
KEGG gene
 K00520 merA; mercuric reductase [EC:1.16.1.1]
KEGG gene
 K00383 GSR, gor; glutathione reductase (NADPH) [EC:1.8.1.7] kornec01100 kornec04918 kornec00480
Gene Ontology
 GO:1990748 cellular detoxification
Gene Ontology
 GO:1901700 response to oxygen-containing compound
Gene Ontology
 GO:1901530 response to hypochlorite
Gene Ontology
 GO:0098869 cellular oxidant detoxification
Gene Ontology
 GO:0098754 detoxification
Gene Ontology
 GO:0097237 cellular response to toxic substance
Gene Ontology
 GO:0070887 cellular response to chemical stimulus
Gene Ontology
 GO:0065008 regulation of biological quality
Gene Ontology
 GO:0065007 biological regulation
Gene Ontology
 GO:0055114 oxidation-reduction process
Gene Ontology
 GO:0051716 cellular response to stimulus
Gene Ontology
 GO:0050896 response to stimulus
Gene Ontology
 GO:0050794 regulation of cellular process
Gene Ontology
 GO:0050789 regulation of biological process
Gene Ontology
 GO:0045454 cell redox homeostasis
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0044424 obsolete intracellular part
Gene Ontology
 GO:0042592 homeostatic process
Gene Ontology
 GO:0042221 response to chemical
Gene Ontology
 GO:0019725 cellular homeostasis
Gene Ontology
 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors
Gene Ontology
 GO:0016491 oxidoreductase activity
Gene Ontology
 GO:0010035 response to inorganic substance
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009636 response to toxic substance
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0006979 response to oxidative stress
Gene Ontology
 GO:0006950 response to stress
Gene Ontology
 GO:0005737 cytoplasm
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005622 intracellular anatomical structure
Gene Ontology
 GO:0005575 cellular_component
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Gene Ontology
 GO:0001101 response to acid chemical
Gene Ontology
 GO:0000305 response to oxygen radical
Gene Ontology
 GO:0000302 response to reactive oxygen species
Gene Product
 FAD-dependent oxidoreductase
Eggnog Protein
 EP:merA
Eggnog Ortholog
 EO:1TP1W
Eggnog Description
 ED:Pyridine nucleotide-disulfide oxidoreductase
EC Number
 EC:1.8.1.7 glutathione-disulfide reductase; glutathione reductase; glutathione reductase (NADPH); NADPH-glutathione reductase; GSH reductase; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase kornec01100 kornec00480
EC Number
 EC:1.16.1.1 mercury(II) reductase; mercuric reductase; mercurate(II) reductase; mercuric ion reductase; mercury reductase; reduced NADP:mercuric ion oxidoreductase; mer A

Occurs in the following pathway maps:

Pathway Description
kornec00480 Glutathione metabolism
kornec01100 Metabolic pathways
kornec04918 Thyroid hormone synthesis

Sequences

Nucleotide sequence (GC-content: 54.5 %):

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ATGAAGAAAGTTCAGAATATTGTGATTGGGTTTGGCAAGGGTGGCAAGACGCTTGCCAAGTTCTTAGCTCAGCGTGGCGAAGAGGTATTAGTGGTGGAAAAGTCACAGCAGATGTATGGCGGGACCTGCATCAACATTGCCTGCTTGCCATCGAAGCGGTTGGTTACGGAAGCGGCACGGGGAACCGACTTTGCGACGGCCATTAAGGGAAAAATAGAGATGGTCGCGCAATTACGGAATAAGAATTACCATATGCTGGCGGACGAGGAGACGGTCACGGTGTTGGATGGGACCGCTCATTTTACCGGCAACCATACGATCGCGGTTGAAACGGCCACCGGAACCGAAGAATATGAGGGCGGGCGCATCTTTACCAATACCGGTGCGACCCCGAATATCCCCGCAATTCCCGGTCTGAAGGATAGTCAAGCACTCCTGACCTCAACAACCGCGATGGAACTGCCGGAACTACCCGCTAGGCTGGTGATTATCGGGGCGGGCTATATTGGTCTTGAATTTGCGGCGATGTTTGCCAGCTTCGGCGCGCAGGTCACAGTGCTGGATCACCATGCAACTTTCCTGCCTCGTGAAGATGATGACGTGGCGGCGATGGTAAAGGAAAACCTGGCGAAGCTCGGCGTTGAGATCAAGATGGGTGTTGCGATTAAAAAGGTCACGGACGAGGCCGGTCAAGCGGTGGTTAGGTACGAAGAGCAGGGGAACGAGCAAGGCGTTTCGGCTGATAAAATCCTCGTGGCGGCCGGTCGTCACCCGGTTACCGAAAACCTGGGCCTCGAAAATACCGACATCCAGTTGACGGACCAGGGCGCAATCAAGGTTGATCCTCATCTTCATACTACCGTTCCAAATGTTTGGGCCATCGGCGACGCAAAGGGCGGTCCCCAGTTTACCTACATTTCGTTAGACGACTTCCGGATCATCAAGGACGAACTCTTTGGTGACGGGACGCGCCAGACGACCAACCGGGGTGTGGTTCCGACTAGCGTCTTCATCGAGCCGCCACTGTCACAGGTGGGCTTAACCGAAAAGCAGGCCCAGGCGGCGGGGAAGGATTACCAGCTATTCAAGCTGCCGGTTGCCGCCATTCCTAAGGCGAAAGTACTGAAGGATCAGCGGGGGATGTTGAAGATGCTGGTTGATCCGGCGACAAAAGAAATTATCGGGGCGACGATCTACGCCCCTGAGTCACACGAGATCATTAACATGGTCGCCCTCGCAATGCGGGCCAAGCTCCCATACACCATGCTGCGCGACCAGATTTACACCCACCCGACGATCAGCGAAGGCTTCAATGATTTATTGAAGAAGCCGGTGAAATAA

Protein sequence:

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MKKVQNIVIGFGKGGKTLAKFLAQRGEEVLVVEKSQQMYGGTCINIACLPSKRLVTEAARGTDFATAIKGKIEMVAQLRNKNYHMLADEETVTVLDGTAHFTGNHTIAVETATGTEEYEGGRIFTNTGATPNIPAIPGLKDSQALLTSTTAMELPELPARLVIIGAGYIGLEFAAMFASFGAQVTVLDHHATFLPREDDDVAAMVKENLAKLGVEIKMGVAIKKVTDEAGQAVVRYEEQGNEQGVSADKILVAAGRHPVTENLGLENTDIQLTDQGAIKVDPHLHTTVPNVWAIGDAKGGPQFTYISLDDFRIIKDELFGDGTRQTTNRGVVPTSVFIEPPLSQVGLTEKQAQAAGKDYQLFKLPVAAIPKAKVLKDQRGMLKMLVDPATKEIIGATIYAPESHEIINMVALAMRAKLPYTMLRDQIYTHPTISEGFNDLLKKPVK

GenBank Info

locus_tag - FAM19471-i1-1.1_000965
inference - COORDINATES: similar to AA sequence:RefSeq:WP_007124394.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - FAD-dependent oxidoreductase
protein_id - extdb:FAM19471-i1-1.1_000965

Gene locus (click to toggle display options) expand

Located on scaffold FAM19471-i1-1_scf0015

Update range to 10000 bp

Cellular location expand

Responsible annotations:
SL-0229: GO:0005622 intracellular anatomical structure
SL-0086: GO:0005737 cytoplasm
FAM19471-i1-1.1_000964
FAM19471-i1-1.1_000966