locus tag: FAM19471-i1-1.1_000891 genome: FAM19471-i1-1.1
species: Limosilactobacillus fermentum taxid: 1613

Annotations

Type Name Description Pathways
Gene Product
 homoserine dehydrogenase
KEGG reaction
 R01775 L-homoserine:NADP+ oxidoreductase; L-Homoserine + NADP+ <=> L-Aspartate 4-semialdehyde + NADPH + H+ kornec01230 kornec01100 kornec00260 kornec00270 kornec01110 kornec01120 kornec00300
KEGG reaction
 R01773 L-Homoserine:NAD+ oxidoreductase; L-Homoserine + NAD+ <=> L-Aspartate 4-semialdehyde + NADH + H+ kornec01230 kornec01100 kornec00260 kornec00270 kornec01110 kornec01120 kornec00300
KEGG reaction
 R00480 ATP:L-aspartate 4-phosphotransferase; ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate kornec01230 kornec01100 kornec00260 kornec00270 kornec01110 kornec00261 kornec01120 kornec00300 kornec01210
Ortholog
 N0.HOG0001337 homoserine dehydrogenase
KEGG gene
 K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] kornec01230 kornec01100 kornec00260 kornec00270 kornec01110 kornec00261 kornec01120 kornec00300
KEGG gene
 K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] kornec01230 kornec01100 kornec00260 kornec00270 kornec01110 kornec01120 kornec00300
Gene Ontology
 GO:1901607 alpha-amino acid biosynthetic process
Gene Ontology
 GO:1901605 alpha-amino acid metabolic process
Gene Ontology
 GO:1901576 organic substance biosynthetic process
Gene Ontology
 GO:1901566 organonitrogen compound biosynthetic process
Gene Ontology
 GO:1901564 organonitrogen compound metabolic process
Gene Ontology
 GO:0071944 cell periphery
Gene Ontology
 GO:0071704 organic substance metabolic process
Gene Ontology
 GO:0055114 oxidation-reduction process
Gene Ontology
 GO:0046394 carboxylic acid biosynthetic process
Gene Ontology
 GO:0044464 obsolete cell part
Gene Ontology
 GO:0044283 small molecule biosynthetic process
Gene Ontology
 GO:0044281 small molecule metabolic process
Gene Ontology
 GO:0044249 cellular biosynthetic process
Gene Ontology
 GO:0044238 primary metabolic process
Gene Ontology
 GO:0044237 cellular metabolic process
Gene Ontology
 GO:0043436 oxoacid metabolic process
Gene Ontology
 GO:0040007 growth
Gene Ontology
 GO:0030312 external encapsulating structure
Gene Ontology
 GO:0019752 carboxylic acid metabolic process
Gene Ontology
 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Gene Ontology
 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
Gene Ontology
 GO:0016491 oxidoreductase activity
Gene Ontology
 GO:0016053 organic acid biosynthetic process
Gene Ontology
 GO:0016020 membrane
Gene Ontology
 GO:0009987 cellular process
Gene Ontology
 GO:0009088 threonine biosynthetic process
Gene Ontology
 GO:0009067 aspartate family amino acid biosynthetic process
Gene Ontology
 GO:0009066 aspartate family amino acid metabolic process
Gene Ontology
 GO:0009058 biosynthetic process
Gene Ontology
 GO:0008652 cellular amino acid biosynthetic process
Gene Ontology
 GO:0008152 metabolic process
Gene Ontology
 GO:0008150 biological_process
Gene Ontology
 GO:0006807 nitrogen compound metabolic process
Gene Ontology
 GO:0006566 threonine metabolic process
Gene Ontology
 GO:0006520 cellular amino acid metabolic process
Gene Ontology
 GO:0006082 organic acid metabolic process
Gene Ontology
 GO:0005886 plasma membrane
Gene Ontology
 GO:0005623 obsolete cell
Gene Ontology
 GO:0005618 cell wall
Gene Ontology
 GO:0005575 cellular_component
Gene Ontology
 GO:0004412 homoserine dehydrogenase activity
Gene Ontology
 GO:0003824 catalytic activity
Gene Ontology
 GO:0003674 molecular_function
Eggnog Protein
 EP:hom
Eggnog Ortholog
 EO:1TQ2H
Eggnog Description
 ED:homoserine dehydrogenase
EC Number
 EC:2.7.2.4 aspartate kinase; aspartokinase; AK; beta-aspartokinase; aspartic kinase kornec01100 kornec00260 kornec00270 kornec01110 kornec00261 kornec01120 kornec00300
EC Number
 EC:1.1.1.3 homoserine dehydrogenase; HSDH; HSD kornec01100 kornec00260 kornec00270 kornec01110 kornec01120 kornec00300

Occurs in the following pathway maps:

Pathway Description
kornec00260 Glycine, serine and threonine metabolism
kornec00261 Monobactam biosynthesis
kornec00270 Cysteine and methionine metabolism
kornec00300 Lysine biosynthesis
kornec01100 Metabolic pathways
kornec01110 Biosynthesis of secondary metabolites
kornec01120 Microbial metabolism in diverse environments
kornec01210 2-Oxocarboxylic acid metabolism
kornec01230 Biosynthesis of amino acids

Sequences

Nucleotide sequence (GC-content: 56.2 %):

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ATGAGAGAAATCAAAGTTGGCTTACTGGGGCTCGGCACGGTCGGGTCCGGAGTGTTAAAAATGATTCAAGAAAACGGGGATAAAATTACGAACGTCACCGGACAGCGGATCACCGTGAAAACGGCGCTGGTCCGTAATCCGGCCAAGCACGAGGCCGTGGCCGACTCGGTTACCTTAACGACCGACTTCGCCGAGATCTTAAATGACGAGGAAATCGACATCGCCGTTGAATTACTGGGCGGGTTGCACCCGGCTGAAGAATACATCACCGCCCTTTTAAAACAGCACAAGCACGTCGTTACCGCCAACAAGGATTTAATCGCCGCCGTTGGTCCCCGCTTGGCCCAGTTGGCTCACGATAACCACTGCGACCTAATGTATGAGGCCAGCGTGGCCGGGGGGATCCCAATCCTGCGCACGATTGCCAATAGTTTTTCGGCCGACCAGATCTTGGAGGTCAAGGGGATCGTCAACGGGACGACCAACTACATCCTCACCCAAATGGCTAAGCAGGGGCTCGATTACGATACTGCCCTCAAACAGGCCCAGGAGCTCGGCTTTGCCGAGGCTGACCCAACCAACGACGTTAAGGGAAAGGACGCCGCCTTTAAGATGGTCATCTTGAGCCACTTTGCCTTCGGGACCGAGGTCGCCGTCGATGAGTTAGAAATCGTTGGGATCGATCAATTGACCAAAGAAGACGTCGCCCAAGCATCAAAGCTCGGCTACGTTGTCAAGCTGGTTGGGTTAGCCAAGGTGGTCAACCACGGTCTCTTCGTCGAGGTGGCGCCCACTTTGGTCAACCAGTCCCACCCACTGGCTTCAATTAACAACGAAAACAACGCCGTGATGGTGACGGGCCAAGCGGTCGGCGACACTCTCTTTTACGGGCCCGGTGCCGGGGGCTTACCCACCGCTAACAGCGTCTTGAGCGACATTACCTCCACCACCAAAAACCTGGTGTTAAAGACGACTGGGAACTCCTTTAATAACTTCGCCCAGGAGTTAGGCCCCGCCGACCCCAAGGCGGTTAGTTTCCCTTACTACCTGTCCTTGAAGATGCCGGACGTGCCGGGGCAAATGCAGCAGCTAGCCGGCTTGATGACCCAGGTGGGCGCTAGCTTCCAGCAGCTGGTGCAAACCGCCGCCCACCAGGGGCACGCCCACGTGGTCGTGATCACCCACGCCATTAACCAGGCCCAACTGGCCCAACTTAAGGAACTGCTTGACCAGTCACCAACCCTGTCCTTACAGGCGGCCTACAAGGTTTTAGATTAG

Protein sequence:

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MREIKVGLLGLGTVGSGVLKMIQENGDKITNVTGQRITVKTALVRNPAKHEAVADSVTLTTDFAEILNDEEIDIAVELLGGLHPAEEYITALLKQHKHVVTANKDLIAAVGPRLAQLAHDNHCDLMYEASVAGGIPILRTIANSFSADQILEVKGIVNGTTNYILTQMAKQGLDYDTALKQAQELGFAEADPTNDVKGKDAAFKMVILSHFAFGTEVAVDELEIVGIDQLTKEDVAQASKLGYVVKLVGLAKVVNHGLFVEVAPTLVNQSHPLASINNENNAVMVTGQAVGDTLFYGPGAGGLPTANSVLSDITSTTKNLVLKTTGNSFNNFAQELGPADPKAVSFPYYLSLKMPDVPGQMQQLAGLMTQVGASFQQLVQTAAHQGHAHVVVITHAINQAQLAQLKELLDQSPTLSLQAAYKVLD

GenBank Info

locus_tag - FAM19471-i1-1.1_000891
inference - COORDINATES: similar to AA sequence:RefSeq:WP_014562494.1
note - Derived by automated computational analysis using gene prediction method: Protein Homology.
codon_start - 1
transl_table - 11
product - homoserine dehydrogenase
protein_id - extdb:FAM19471-i1-1.1_000891

Gene locus (click to toggle display options) expand

Located on scaffold FAM19471-i1-1_scf0013

Update range to 10000 bp

Cellular location expand

Responsible annotations:
SL-0041: GO:0005618 cell wall
SL-0162: GO:0016020 membrane
SL-0039: GO:0005886 plasma membrane
FAM19471-i1-1.1_000890
FAM19471-i1-1.1_000892