## Fri Feb 4 11:44:36 2022 ## emapper-2.1.6 ## /data/projects/p446_Dialact_Phoenix/6_open_genome_browser/OgbClusterServer/venv/bin/emapper.py --annotate_hits_table /data/projects/p446_Dialact_Phoenix/6_open_genome_browser/dialact/organisms/FAM24227/genomes/FAM24227-i1-1.1/3_annotation/FAM24227-i1-1.1.emapper.seed_orthologs --data_dir /dev/shm/eggnog/data -o /data/projects/p446_Dialact_Phoenix/6_open_genome_browser/dialact/organisms/FAM24227/genomes/FAM24227-i1-1.1/3_annotation/FAM24227-i1-1.1 --cpu 20 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs gnl|extdb|FAM24227-i1-1.1_000002 938278.CAJO01000049_gene372 4.71e-18 79.0 COG1550@1|root,COG1550@2|Bacteria 2|Bacteria H Protein conserved in bacteria ylxP - - ko:K09764 - - - - ko00000 - - - DUF503 gnl|extdb|FAM24227-i1-1.1_000003 866775.HMPREF9243_1051 2.29e-55 177.0 COG5015@1|root,COG5015@2|Bacteria,1TR2Q@1239|Firmicutes,4HHXT@91061|Bacilli,27ERQ@186827|Aerococcaceae 91061|Bacilli C Pyridoxamine 5'-phosphate oxidase family protein - - - - - - - - - - - - Putative_PNPOx gnl|extdb|FAM24227-i1-1.1_000004 208596.CAR_c22320 1.12e-112 328.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,27FTQ@186828|Carnobacteriaceae 91061|Bacilli F Deoxynucleoside kinase - - - - - - - - - - - - dNK gnl|extdb|FAM24227-i1-1.1_000005 208596.CAR_c17580 1.91e-166 483.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,27FA5@186828|Carnobacteriaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 gnl|extdb|FAM24227-i1-1.1_000006 1121024.AUCD01000029_gene1277 4.57e-103 306.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,27G3X@186828|Carnobacteriaceae 91061|Bacilli S Prolyl oligopeptidase family yitV - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 gnl|extdb|FAM24227-i1-1.1_000007 1175629.AJTG01000019_gene1625 3.85e-62 202.0 COG1187@1|root,COG1187@2|Bacteria,1V4MR@1239|Firmicutes,4HGZM@91061|Bacilli,27E3R@186827|Aerococcaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA - 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 gnl|extdb|FAM24227-i1-1.1_000008 1408438.JADD01000029_gene1372 1.86e-51 168.0 28SQR@1|root,2ZF0S@2|Bacteria,1W39R@1239|Firmicutes 1239|Firmicutes U MotA/TolQ/ExbB proton channel family - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB gnl|extdb|FAM24227-i1-1.1_000012 1122143.AUEG01000002_gene751 7.9e-59 190.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,27HKF@186828|Carnobacteriaceae 91061|Bacilli S SOS response associated peptidase (SRAP) yoqW - - - - - - - - - - - SRAP gnl|extdb|FAM24227-i1-1.1_000013 1266845.Q783_08995 1.02e-48 160.0 COG1764@1|root,COG1764@2|Bacteria,1V7KG@1239|Firmicutes,4HJ7U@91061|Bacilli,27GI3@186828|Carnobacteriaceae 91061|Bacilli O OsmC-like protein ohr - - - - - - - - - - - OsmC gnl|extdb|FAM24227-i1-1.1_000014 1121024.AUCD01000019_gene469 9.1e-99 304.0 COG1537@1|root,COG1537@2|Bacteria,1UPQ9@1239|Firmicutes,4IV8X@91061|Bacilli,27I51@186828|Carnobacteriaceae 91061|Bacilli S nuclear-transcribed mRNA catabolic process, no-go decay - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000015 208596.CAR_c09470 1.73e-97 295.0 COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,4H9MM@91061|Bacilli,27FDT@186828|Carnobacteriaceae 91061|Bacilli E Substrate binding domain of ABC-type glycine betaine transport system busAB - - ko:K02001,ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC gnl|extdb|FAM24227-i1-1.1_000016 1160707.AJIK01000012_gene155 2.38e-126 368.0 COG4176@1|root,COG4176@2|Bacteria,1UHRI@1239|Firmicutes,4IS7D@91061|Bacilli,26EHC@186818|Planococcaceae 91061|Bacilli E Binding-protein-dependent transport system inner membrane component opuAB - - ko:K02001,ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000017 1122143.AUEG01000002_gene904 2.12e-187 533.0 COG4175@1|root,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,4HA9P@91061|Bacilli,27FP0@186828|Carnobacteriaceae 91061|Bacilli E Domain in cystathionine beta-synthase and other proteins. opuAA - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS gnl|extdb|FAM24227-i1-1.1_000018 1121024.AUCD01000112_gene356 5.12e-55 178.0 COG4297@1|root,COG4297@2|Bacteria,1V6MJ@1239|Firmicutes,4HJGB@91061|Bacilli,27HAW@186828|Carnobacteriaceae 91061|Bacilli S protein containing double-stranded beta helix domain yjlB - - - - - - - - - - - Cupin_1,Cupin_2 gnl|extdb|FAM24227-i1-1.1_000019 1449342.JQMR01000001_gene1377 8.61e-22 90.1 2ER98@1|root,33IUV@2|Bacteria,1VNFV@1239|Firmicutes,4HRP4@91061|Bacilli,27HMP@186828|Carnobacteriaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000020 655812.HMPREF0061_0144 1.93e-41 143.0 COG0628@1|root,COG0628@2|Bacteria,1W77C@1239|Firmicutes,4HYAF@91061|Bacilli,27EXZ@186827|Aerococcaceae 91061|Bacilli S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport gnl|extdb|FAM24227-i1-1.1_000021 1449335.JQLG01000004_gene897 8e-99 292.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,27FR7@186828|Carnobacteriaceae 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD gnl|extdb|FAM24227-i1-1.1_000022 476272.RUMHYD_00905 3.37e-79 246.0 COG3836@1|root,COG3836@2|Bacteria,1UZZG@1239|Firmicutes,25HYT@186801|Clostridia,3Y1Z8@572511|Blautia 186801|Clostridia G HpcH/HpaI aldolase/citrate lyase family - - - - - - - - - - - - HpcH_HpaI gnl|extdb|FAM24227-i1-1.1_000023 904293.HMPREF9176_0619 7.31e-52 178.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 gnl|extdb|FAM24227-i1-1.1_000024 565653.EGBG_00791 8.6e-110 325.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,4B0GA@81852|Enterococcaceae 91061|Bacilli S Aldo/keto reductase family morA - - - - - - - - - - - Aldo_ket_red gnl|extdb|FAM24227-i1-1.1_000025 1408438.JADD01000004_gene1031 4.5e-87 270.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK7D@91061|Bacilli,27F3Q@186827|Aerococcaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 gnl|extdb|FAM24227-i1-1.1_000027 883103.HMPREF9703_00186 3.85e-94 280.0 COG0431@1|root,COG0431@2|Bacteria,1TT2S@1239|Firmicutes,4HBQI@91061|Bacilli,27FXD@186828|Carnobacteriaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red gnl|extdb|FAM24227-i1-1.1_000028 1121024.AUCD01000007_gene1987 6.81e-197 557.0 COG0431@1|root,COG2461@1|root,COG0431@2|Bacteria,COG2461@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli,27G2P@186828|Carnobacteriaceae 91061|Bacilli S NADPH-dependent FMN reductase XK27_09615 - - ko:K19784 - - - - ko00000 - - - FMN_red,PAS_10 gnl|extdb|FAM24227-i1-1.1_000030 1158607.UAU_04543 7.24e-125 367.0 COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,4B2WX@81852|Enterococcaceae 91061|Bacilli F Inosine-uridine preferring nucleoside hydrolase iunH1 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro gnl|extdb|FAM24227-i1-1.1_000031 411474.COPEUT_02909 2.27e-107 310.0 COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,24BYP@186801|Clostridia 186801|Clostridia S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF gnl|extdb|FAM24227-i1-1.1_000032 626369.HMPREF0446_01630 4.11e-95 283.0 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC gnl|extdb|FAM24227-i1-1.1_000033 626369.HMPREF0446_01629 1.04e-60 191.0 COG4708@1|root,COG4708@2|Bacteria 2|Bacteria F membrane - - - - - - - - - - - - QueT gnl|extdb|FAM24227-i1-1.1_000034 1121024.AUCD01000076_gene982 4.73e-86 258.0 COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,27GPA@186828|Carnobacteriaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yokL3 - - - - - - - - - - - Acetyltransf_3 gnl|extdb|FAM24227-i1-1.1_000036 1263831.F543_12380 2.38e-157 451.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1Y7G0@135625|Pasteurellales 135625|Pasteurellales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C gnl|extdb|FAM24227-i1-1.1_000037 1263831.F543_12390 7.87e-73 225.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1Y7PG@135625|Pasteurellales 135625|Pasteurellales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N gnl|extdb|FAM24227-i1-1.1_000038 1263831.F543_12400 4.07e-239 674.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1Y6XQ@135625|Pasteurellales 135625|Pasteurellales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS gnl|extdb|FAM24227-i1-1.1_000039 1121105.ATXL01000006_gene1344 1.27e-140 415.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,4B139@81852|Enterococcaceae 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N gnl|extdb|FAM24227-i1-1.1_000040 1263831.F543_12430 2.92e-64 201.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1Y77H@135625|Pasteurellales 135625|Pasteurellales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC gnl|extdb|FAM24227-i1-1.1_000041 883110.HMPREF9260_01035 1.86e-146 427.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,27DUX@186827|Aerococcaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp gnl|extdb|FAM24227-i1-1.1_000042 1122129.AUEF01000010_gene1526 1.77e-91 275.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,4GXTP@90964|Staphylococcaceae 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt gnl|extdb|FAM24227-i1-1.1_000043 883110.HMPREF9260_01033 0.0 1260.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,27EB2@186827|Aerococcaceae 91061|Bacilli F CobB/CobQ-like glutamine amidotransferase domain purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 gnl|extdb|FAM24227-i1-1.1_000044 1469948.JPNB01000001_gene848 2.11e-63 211.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,36F5I@31979|Clostridiaceae 186801|Clostridia K Transcriptional regulator, LacI family - - 5.1.1.1 ko:K01775,ko:K02529,ko:K05499 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011,ko03000 - - - LacI,Peripla_BP_3 gnl|extdb|FAM24227-i1-1.1_000045 1284686.HMPREF1630_00960 3.52e-108 328.0 COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,22HR4@1570339|Peptoniphilaceae 186801|Clostridia S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C gnl|extdb|FAM24227-i1-1.1_000046 1298920.KI911353_gene1573 1.86e-110 331.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,25BRG@186801|Clostridia 186801|Clostridia G Periplasmic binding protein domain - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 gnl|extdb|FAM24227-i1-1.1_000047 1232453.BAIF02000001_gene1440 5.06e-188 541.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,26A80@186813|unclassified Clostridiales 186801|Clostridia G ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000048 1298920.KI911353_gene1575 2.03e-108 326.0 COG1172@1|root,COG1172@2|Bacteria,1UYG4@1239|Firmicutes,24A8M@186801|Clostridia,222ZG@1506553|Lachnoclostridium 186801|Clostridia G Branched-chain amino acid transport system / permease component - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 gnl|extdb|FAM24227-i1-1.1_000049 1158610.UC3_01066 6.18e-146 419.0 COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H9KJ@91061|Bacilli,4AZRR@81852|Enterococcaceae 91061|Bacilli G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 gnl|extdb|FAM24227-i1-1.1_000050 861530.ALOZ01000073_gene1571 1.36e-39 137.0 COG2764@1|root,COG2764@2|Bacteria,1VARX@1239|Firmicutes,4HKC2@91061|Bacilli,4H1KH@90964|Staphylococcaceae 91061|Bacilli S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K04750 - - - - ko00000 - - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_000051 1078085.HMPREF1210_03080 5.54e-47 159.0 COG4312@1|root,COG4312@2|Bacteria,1UYI5@1239|Firmicutes,4HF86@91061|Bacilli,26GQS@186818|Planococcaceae 91061|Bacilli S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 gnl|extdb|FAM24227-i1-1.1_000052 1121024.AUCD01000061_gene993 4.41e-110 322.0 COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,4HBM0@91061|Bacilli,27H33@186828|Carnobacteriaceae 91061|Bacilli S Beta-lactamase superfamily domain ytkL - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 gnl|extdb|FAM24227-i1-1.1_000053 748727.CLJU_c07610 7.19e-09 58.2 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein - - - ko:K07397,ko:K19000 - - - - ko00000,ko03021 - - - OsmC gnl|extdb|FAM24227-i1-1.1_000054 1308866.J416_06562 6.51e-84 254.0 COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,4HA6N@91061|Bacilli,471BP@74385|Gracilibacillus 91061|Bacilli J RNA pseudouridylate synthase rluC - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 gnl|extdb|FAM24227-i1-1.1_000056 12336.Q331Z3_CBCP 3.57e-21 90.5 4QBIH@10239|Viruses,4QVPB@35237|dsDNA viruses no RNA stage,4QPJN@28883|Caudovirales,4QJ29@10662|Myoviridae 10662|Myoviridae S MerR family regulatory protein - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000057 1121871.AUAT01000001_gene822 2.29e-19 87.8 COG0491@1|root,COG0491@2|Bacteria,1V3ZB@1239|Firmicutes,4IQC8@91061|Bacilli,27EUC@186827|Aerococcaceae 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B gnl|extdb|FAM24227-i1-1.1_000058 1345697.M493_10975 2.05e-96 298.0 COG0318@1|root,COG0318@2|Bacteria,1UKBR@1239|Firmicutes,4ITH5@91061|Bacilli,1WH7V@129337|Geobacillus 91061|Bacilli IQ Acyl-protein synthetase, LuxE - - - - - - - - - - - - LuxE gnl|extdb|FAM24227-i1-1.1_000059 1160707.AJIK01000024_gene1727 1.47e-128 388.0 COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli,26GR6@186818|Planococcaceae 91061|Bacilli C Acyl-CoA reductase (LuxC) - - - - - - - - - - - - LuxC gnl|extdb|FAM24227-i1-1.1_000060 420246.GTNG_2038 2.07e-73 231.0 COG1116@1|root,COG1116@2|Bacteria,1UZXI@1239|Firmicutes,4HEY4@91061|Bacilli,1WGQV@129337|Geobacillus 91061|Bacilli P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000061 1123290.AUDQ01000004_gene401 3.64e-81 251.0 COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HARZ@91061|Bacilli,26FQH@186818|Planococcaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component tauC - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000062 1160707.AJIK01000024_gene1724 1.02e-119 355.0 COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HEW0@91061|Bacilli,26GEX@186818|Planococcaceae 91061|Bacilli P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 gnl|extdb|FAM24227-i1-1.1_000063 1345697.M493_10950 1.66e-107 318.0 COG1028@1|root,COG1028@2|Bacteria,1UU2F@1239|Firmicutes,4HCVI@91061|Bacilli,1WHEU@129337|Geobacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 gnl|extdb|FAM24227-i1-1.1_000064 1121871.AUAT01000001_gene822 1.33e-61 202.0 COG0491@1|root,COG0491@2|Bacteria,1V3ZB@1239|Firmicutes,4IQC8@91061|Bacilli,27EUC@186827|Aerococcaceae 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B gnl|extdb|FAM24227-i1-1.1_000066 1408438.JADD01000003_gene165 4.71e-40 136.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin gnl|extdb|FAM24227-i1-1.1_000068 1121024.AUCD01000071_gene278 5.31e-161 456.0 COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,4HAW6@91061|Bacilli,27G2Q@186828|Carnobacteriaceae 91061|Bacilli S S-adenosyl-l-methionine hydroxide adenosyltransferase XK27_10120 - - - - - - - - - - - SAM_adeno_trans gnl|extdb|FAM24227-i1-1.1_000069 1121024.AUCD01000071_gene277 1.33e-104 305.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli,27GT8@186828|Carnobacteriaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS gnl|extdb|FAM24227-i1-1.1_000070 1121024.AUCD01000071_gene276 2.72e-293 815.0 COG1123@1|root,COG4172@2|Bacteria,1VRD0@1239|Firmicutes,4ISFN@91061|Bacilli 91061|Bacilli P ABC transporter - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 gnl|extdb|FAM24227-i1-1.1_000071 1121024.AUCD01000071_gene275 5.79e-156 442.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli,27GMF@186828|Carnobacteriaceae 91061|Bacilli P Cobalt transport protein cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ gnl|extdb|FAM24227-i1-1.1_000072 866775.HMPREF9243_0958 1.25e-23 96.7 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli 91061|Bacilli T universal stress protein uspA - - - - - - - - - - - Usp gnl|extdb|FAM24227-i1-1.1_000073 1122143.AUEG01000002_gene860 3.23e-251 701.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,27FRB@186828|Carnobacteriaceae 91061|Bacilli JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes dbpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C gnl|extdb|FAM24227-i1-1.1_000074 1423748.BALB01000020_gene1622 0.000351 43.9 COG2378@1|root,COG2378@2|Bacteria,1TPS2@1239|Firmicutes,4HDVX@91061|Bacilli,3F56I@33958|Lactobacillaceae 91061|Bacilli K WYL domain yobV3 - - - - - - - - - - - HTH_11,WYL gnl|extdb|FAM24227-i1-1.1_000075 1423790.BN53_09900 1.17e-23 96.3 COG1182@1|root,COG1182@2|Bacteria,1V2AQ@1239|Firmicutes,4HGK5@91061|Bacilli,3F580@33958|Lactobacillaceae 91061|Bacilli C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 gnl|extdb|FAM24227-i1-1.1_000076 1121024.AUCD01000047_gene1423 5.82e-192 550.0 COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,4HCWN@91061|Bacilli,27FA2@186828|Carnobacteriaceae 91061|Bacilli P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH gnl|extdb|FAM24227-i1-1.1_000077 1121024.AUCD01000047_gene1422 9.94e-204 577.0 COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,4HCRM@91061|Bacilli,27FDM@186828|Carnobacteriaceae 91061|Bacilli P TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N gnl|extdb|FAM24227-i1-1.1_000078 1408438.JADD01000004_gene1036 1.08e-111 329.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,27DP0@186827|Aerococcaceae 91061|Bacilli D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - - - - - - - - - - AAA_31 gnl|extdb|FAM24227-i1-1.1_000079 1408438.JADD01000004_gene1035 2.8e-72 231.0 COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,4HTUT@91061|Bacilli,27EWJ@186827|Aerococcaceae 91061|Bacilli K ParB-like nuclease domain - - - - - - - - - - - - ParBc gnl|extdb|FAM24227-i1-1.1_000082 1449338.JQLU01000002_gene864 3.46e-64 210.0 COG1451@1|root,COG1451@2|Bacteria,1VCK6@1239|Firmicutes,4HGVM@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2786) - - - - - - - - - - - - DUF2786 gnl|extdb|FAM24227-i1-1.1_000083 1158612.I580_00310 2.16e-27 117.0 2DUI0@1|root,33QS5@2|Bacteria,1VSZG@1239|Firmicutes,4HTBD@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000086 1497679.EP56_17780 5.47e-179 593.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli 91061|Bacilli M domain protein - GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0044877,GO:0051704,GO:0070051,GO:0098630,GO:0098743 - ko:K13732,ko:K13733,ko:K14195 ko05100,ko05150,map05100,map05150 - - - ko00000,ko00001 - - - Cna_B,Collagen_bind,Fn_bind,G5,Gram_pos_anchor,SasG_E,SdrG_C_C,YSIRK_signal gnl|extdb|FAM24227-i1-1.1_000089 1140001.I571_00503 2.18e-06 57.8 2EG0H@1|root,339SH@2|Bacteria,1VP01@1239|Firmicutes,4HS1I@91061|Bacilli,4B1GN@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000092 1132442.KB889755_gene4013 7.92e-49 181.0 COG2856@1|root,COG2856@2|Bacteria,1UMV5@1239|Firmicutes,4IU1B@91061|Bacilli 91061|Bacilli E Pfam:DUF955 - - - - - - - - - - - - Peptidase_M78 gnl|extdb|FAM24227-i1-1.1_000094 1408438.JADD01000031_gene1314 3.65e-168 508.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli 91061|Bacilli U COG3505 Type IV secretory pathway, VirD4 components - - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf gnl|extdb|FAM24227-i1-1.1_000095 1408438.JADD01000031_gene1313 1.36e-41 169.0 COG3266@1|root,COG3266@2|Bacteria,1TSNJ@1239|Firmicutes 1239|Firmicutes S domain, Protein - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000096 1246484.D479_05595 0.000542 44.3 2ENCU@1|root,33G0B@2|Bacteria,1VNFB@1239|Firmicutes,4HSWM@91061|Bacilli 91061|Bacilli S Uncharacterized protein pXO2-11 - - - - - - - - - - - - pXO2-11 gnl|extdb|FAM24227-i1-1.1_000097 1408438.JADD01000031_gene1311 3.24e-55 182.0 2DME1@1|root,32QVI@2|Bacteria,1V94J@1239|Firmicutes,4HK3U@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000098 1408438.JADD01000031_gene1310 2.15e-298 832.0 COG0433@1|root,COG0433@2|Bacteria,1W186@1239|Firmicutes,4HA4T@91061|Bacilli 91061|Bacilli S COG0433 Predicted ATPase - - - - - - - - - - - - DUF87 gnl|extdb|FAM24227-i1-1.1_000101 1408438.JADD01000031_gene1308 4.39e-139 432.0 COG0741@1|root,COG0791@1|root,COG2755@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,COG2755@2|Bacteria,1V6X7@1239|Firmicutes,4HJEB@91061|Bacilli 91061|Bacilli M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) pvaA - - - - - - - - - - - Lysozyme_like gnl|extdb|FAM24227-i1-1.1_000106 1408438.JADD01000031_gene1299 4.62e-74 250.0 COG2255@1|root,COG2255@2|Bacteria,1V0DS@1239|Firmicutes,4HENV@91061|Bacilli 91061|Bacilli L four-way junction helicase activity - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000107 1158604.I591_02832 6.39e-80 243.0 COG1961@1|root,COG1961@2|Bacteria,1UZM8@1239|Firmicutes,4IQ67@91061|Bacilli,4B2AE@81852|Enterococcaceae 91061|Bacilli L Resolvase, N terminal domain tnpR - - - - - - - - - - - HTH_23,HTH_7,Resolvase gnl|extdb|FAM24227-i1-1.1_000108 1408438.JADD01000031_gene1298 2.31e-91 296.0 COG0358@1|root,COG0358@2|Bacteria,1TQKP@1239|Firmicutes,4IQS6@91061|Bacilli 91061|Bacilli L Protein of unknown function (DUF3991) - - - - - - - - - - - - DUF3991,Toprim_2 gnl|extdb|FAM24227-i1-1.1_000110 945021.TEH_04200 6.84e-31 111.0 COG1813@1|root,COG1813@2|Bacteria,1VEXE@1239|Firmicutes,4HQ33@91061|Bacilli,4B3IJ@81852|Enterococcaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 gnl|extdb|FAM24227-i1-1.1_000112 1266845.Q783_01775 8.86e-30 110.0 COG4679@1|root,COG4679@2|Bacteria 2|Bacteria K PFAM Phage derived protein Gp49-like (DUF891) - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - Gp49 gnl|extdb|FAM24227-i1-1.1_000114 1408438.JADD01000031_gene1300 3.46e-55 180.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,27DS8@186827|Aerococcaceae 91061|Bacilli E RadC-like JAB domain radC - - ko:K03630 - - - - ko00000 - - - RadC gnl|extdb|FAM24227-i1-1.1_000115 1123359.AUIQ01000045_gene547 2.5e-37 141.0 2BN0D@1|root,32GKH@2|Bacteria,1U0B0@1239|Firmicutes,4I9MV@91061|Bacilli,4B4GB@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000116 764299.STRIC_0623 1.6e-10 62.4 2EES0@1|root,338JP@2|Bacteria,1VJPW@1239|Firmicutes,4HPSW@91061|Bacilli 91061|Bacilli S Bacteriophage holin family - - - - - - - - - - - - Phage_holin_4_1 gnl|extdb|FAM24227-i1-1.1_000117 1158604.I591_02274 1.45e-18 87.0 28RIV@1|root,2ZDXS@2|Bacteria,1W23E@1239|Firmicutes,4HZIE@91061|Bacilli,4B3A3@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000121 1408422.JHYF01000007_gene1302 1.23e-06 57.8 COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,36JNY@31979|Clostridiaceae 186801|Clostridia L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase gnl|extdb|FAM24227-i1-1.1_000124 756499.Desde_2153 2.37e-66 210.0 COG0288@1|root,COG0288@2|Bacteria,1V1YB@1239|Firmicutes,24GMG@186801|Clostridia,261GG@186807|Peptococcaceae 186801|Clostridia P Reversible hydration of carbon dioxide cynT - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA gnl|extdb|FAM24227-i1-1.1_000125 683837.lse_1721 3.15e-38 135.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli,26J6T@186820|Listeriaceae 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI gnl|extdb|FAM24227-i1-1.1_000126 226185.EF_1566 6.36e-164 475.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,4B0JV@81852|Enterococcaceae 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase gnl|extdb|FAM24227-i1-1.1_000127 1175629.AJTG01000028_gene46 1.06e-187 533.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt gnl|extdb|FAM24227-i1-1.1_000128 1175629.AJTG01000006_gene626 4.62e-96 292.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,27ETW@186827|Aerococcaceae 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N gnl|extdb|FAM24227-i1-1.1_000129 655812.HMPREF0061_1899 9.86e-121 360.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase gnl|extdb|FAM24227-i1-1.1_000130 655812.HMPREF0061_1900 3.79e-128 375.0 COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli 91061|Bacilli E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate aroF - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 gnl|extdb|FAM24227-i1-1.1_000131 1121289.JHVL01000061_gene2546 4.01e-159 457.0 COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,249F8@186801|Clostridia,36FBR@31979|Clostridiaceae 186801|Clostridia S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - Acetyltransf_1,RsgA_GTPase gnl|extdb|FAM24227-i1-1.1_000132 1408438.JADD01000004_gene1052 3.85e-184 517.0 COG0435@1|root,COG0435@2|Bacteria,1TQXQ@1239|Firmicutes,4H9VF@91061|Bacilli,27EG9@186827|Aerococcaceae 91061|Bacilli O Glutathione S-transferase, N-terminal domain XK27_04695 - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 gnl|extdb|FAM24227-i1-1.1_000133 655812.HMPREF0061_0538 8.68e-125 368.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HCUU@91061|Bacilli 91061|Bacilli E Ornithine cyclodeaminase/mu-crystallin family - - 1.4.1.1 ko:K19244 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall gnl|extdb|FAM24227-i1-1.1_000136 1408438.JADD01000019_gene823 8.41e-63 196.0 2AYCG@1|root,31QF9@2|Bacteria,1V791@1239|Firmicutes,4HIQI@91061|Bacilli,27ERN@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000137 1121024.AUCD01000014_gene1838 8.21e-106 311.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,27FVZ@186828|Carnobacteriaceae 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG gnl|extdb|FAM24227-i1-1.1_000138 888833.HMPREF9421_1498 4.43e-39 137.0 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli 91061|Bacilli M acetyltransferase pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 gnl|extdb|FAM24227-i1-1.1_000139 1122918.KB907254_gene3276 2.23e-40 143.0 COG2890@1|root,COG2890@2|Bacteria,1UMTH@1239|Firmicutes,4ITZU@91061|Bacilli 91061|Bacilli J protein-(glutamine-N5) methyltransferase activity - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000140 1121871.AUAT01000004_gene1077 4.86e-114 361.0 COG0860@1|root,COG0860@2|Bacteria,1VATU@1239|Firmicutes,4HN3V@91061|Bacilli,27EHN@186827|Aerococcaceae 91061|Bacilli M Ami_3 amiD2 - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,CW_binding_1,LysM gnl|extdb|FAM24227-i1-1.1_000141 1408438.JADD01000019_gene821 6.78e-111 323.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,27DH7@186827|Aerococcaceae 91061|Bacilli P ABC transporter, permease protein arpJ - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_000142 883103.HMPREF9703_00795 1.14e-38 133.0 COG0526@1|root,COG0526@2|Bacteria,1VH4P@1239|Firmicutes,4HQBD@91061|Bacilli,27GQN@186828|Carnobacteriaceae 91061|Bacilli CO transport accessory protein bta - - - - - - - - - - - Thioredoxin,TraF gnl|extdb|FAM24227-i1-1.1_000143 1408438.JADD01000020_gene1485 4.59e-91 296.0 2CVQH@1|root,32SY0@2|Bacteria,1VE88@1239|Firmicutes,4HKII@91061|Bacilli,27E4E@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000144 883112.HMPREF9707_00564 7.68e-145 423.0 COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,4HB06@91061|Bacilli,27EHT@186827|Aerococcaceae 91061|Bacilli M Bacterial capsule synthesis protein PGA_cap capA - - ko:K07282 - - - - ko00000 - - - PGA_cap gnl|extdb|FAM24227-i1-1.1_000145 1408438.JADD01000009_gene1801 0.0 1696.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,27DE7@186827|Aerococcaceae 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA gnl|extdb|FAM24227-i1-1.1_000146 1408438.JADD01000009_gene1802 1.93e-58 189.0 COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,27EU9@186827|Aerococcaceae 91061|Bacilli L Staphylococcal nuclease homologues - - - - - - - - - - - - Excalibur,SNase gnl|extdb|FAM24227-i1-1.1_000147 592010.GCWU000182_001527 1.12e-40 140.0 COG3444@1|root,COG3444@2|Bacteria,1UXMT@1239|Firmicutes,4I36P@91061|Bacilli,27E9J@186827|Aerococcaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - - - - - - - - - - - PTSIIB_sorb gnl|extdb|FAM24227-i1-1.1_000148 592010.GCWU000182_001528 1.08e-116 351.0 COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,4HJVA@91061|Bacilli,27DZ0@186827|Aerococcaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18 gnl|extdb|FAM24227-i1-1.1_000149 908337.HMPREF9257_1165 1.64e-35 121.0 COG0695@1|root,COG0695@2|Bacteria,1VK60@1239|Firmicutes,4I3VG@91061|Bacilli,27E7J@186827|Aerococcaceae 91061|Bacilli O Glutaredoxin - - - ko:K06191 - - - - ko00000 - - - Glutaredoxin gnl|extdb|FAM24227-i1-1.1_000150 1449336.JQLO01000001_gene922 1.27e-45 162.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HG3E@91061|Bacilli 91061|Bacilli V proteins, homologs of microcin C7 resistance protein MccF - - - - - - - - - - - - Peptidase_S66 gnl|extdb|FAM24227-i1-1.1_000151 1408438.JADD01000009_gene1806 1.08e-103 308.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,27DU3@186827|Aerococcaceae 91061|Bacilli S ABC transporter, ATP-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000152 908337.HMPREF9257_1167 8.12e-114 337.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,27DQ3@186827|Aerococcaceae 91061|Bacilli S branched-chain amino acid ABC transporter, permease protein XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 gnl|extdb|FAM24227-i1-1.1_000153 1408438.JADD01000009_gene1808 1.52e-117 349.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,27DXP@186827|Aerococcaceae 91061|Bacilli S ABC transporter substrate binding protein ABC-SBP - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind gnl|extdb|FAM24227-i1-1.1_000154 883112.HMPREF9707_00561 1.85e-234 665.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,27DI4@186827|Aerococcaceae 91061|Bacilli K Fibronectin-binding protein A N-terminus (FbpA) FbpA - - - - - - - - - - - DUF814,FbpA gnl|extdb|FAM24227-i1-1.1_000155 1121871.AUAT01000003_gene1802 9.82e-129 376.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,27DJP@186827|Aerococcaceae 91061|Bacilli C DHHA2 ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 gnl|extdb|FAM24227-i1-1.1_000156 1121871.AUAT01000003_gene1801 0.0 1088.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,27DF6@186827|Aerococcaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV gnl|extdb|FAM24227-i1-1.1_000157 1408438.JADD01000009_gene1814 0.0 1038.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,27DCC@186827|Aerococcaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim gnl|extdb|FAM24227-i1-1.1_000159 1408438.JADD01000009_gene1818 1.55e-109 326.0 COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,27DUC@186827|Aerococcaceae 91061|Bacilli G Aldose 1-epimerase lacX - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim gnl|extdb|FAM24227-i1-1.1_000160 883112.HMPREF9707_00553 1.23e-245 685.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,27EFP@186827|Aerococcaceae 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small gnl|extdb|FAM24227-i1-1.1_000161 1408438.JADD01000009_gene1820 4.33e-96 282.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,27EHA@186827|Aerococcaceae 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome gnl|extdb|FAM24227-i1-1.1_000162 883112.HMPREF9707_00551 7.69e-128 373.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,27DTX@186827|Aerococcaceae 91061|Bacilli D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase gnl|extdb|FAM24227-i1-1.1_000163 1408438.JADD01000009_gene1822 0.0 1091.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,27DGG@186827|Aerococcaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom gnl|extdb|FAM24227-i1-1.1_000164 1408438.JADD01000009_gene1823 3e-81 254.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,27DXF@186827|Aerococcaceae 91061|Bacilli LU DNA recombination-mediator protein A dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A gnl|extdb|FAM24227-i1-1.1_000165 592010.GCWU000182_001554 2.55e-79 247.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,27DV9@186827|Aerococcaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII gnl|extdb|FAM24227-i1-1.1_000166 1408438.JADD01000009_gene1825 5.03e-130 377.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,27DBV@186827|Aerococcaceae 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 gnl|extdb|FAM24227-i1-1.1_000167 592010.GCWU000182_001556 2.04e-73 227.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,27F60@186827|Aerococcaceae 91061|Bacilli U Signal peptidase, peptidase S26 lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 gnl|extdb|FAM24227-i1-1.1_000168 1408438.JADD01000009_gene1826 2.72e-172 500.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,27DR3@186827|Aerococcaceae 91061|Bacilli M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 gnl|extdb|FAM24227-i1-1.1_000169 883112.HMPREF9707_00545 1.63e-137 392.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli,27DSD@186827|Aerococcaceae 91061|Bacilli F Phosphorylase superfamily deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 gnl|extdb|FAM24227-i1-1.1_000170 908337.HMPREF9257_1184 3.14e-26 98.2 COG4479@1|root,COG4479@2|Bacteria,1TX5Z@1239|Firmicutes,4I62E@91061|Bacilli,27EA0@186827|Aerococcaceae 91061|Bacilli S Belongs to the UPF0346 family - - - - - - - - - - - - YozE_SAM_like gnl|extdb|FAM24227-i1-1.1_000172 592010.GCWU000182_001560 4.88e-87 263.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,27DVF@186827|Aerococcaceae 91061|Bacilli S Channel protein, hemolysin III family hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII gnl|extdb|FAM24227-i1-1.1_000173 592010.GCWU000182_000016 3.15e-127 372.0 COG0596@1|root,COG0596@2|Bacteria,1TRAQ@1239|Firmicutes,4HCI9@91061|Bacilli,27DEQ@186827|Aerococcaceae 91061|Bacilli S Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 gnl|extdb|FAM24227-i1-1.1_000174 626369.HMPREF0446_00739 8.45e-69 220.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4HHXM@91061|Bacilli,27I0X@186828|Carnobacteriaceae 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer gnl|extdb|FAM24227-i1-1.1_000175 1121105.ATXL01000006_gene1335 4.12e-238 663.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,4AZ9A@81852|Enterococcaceae 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 gnl|extdb|FAM24227-i1-1.1_000176 883110.HMPREF9260_00358 4.25e-69 213.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,27E0S@186827|Aerococcaceae 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 gnl|extdb|FAM24227-i1-1.1_000177 592010.GCWU000182_000018 2.18e-167 474.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,27DHA@186827|Aerococcaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt gnl|extdb|FAM24227-i1-1.1_000178 1408438.JADD01000016_gene704 8.82e-275 772.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,27DFU@186827|Aerococcaceae 91061|Bacilli S ABC transporter, ATP-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn gnl|extdb|FAM24227-i1-1.1_000179 908337.HMPREF9257_1190 1.73e-269 753.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27EM8@186827|Aerococcaceae 91061|Bacilli V ABC transporter transmembrane region ywjA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_000181 883112.HMPREF9707_00538 6.08e-273 761.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,27DFE@186827|Aerococcaceae 91061|Bacilli H Belongs to the formate--tetrahydrofolate ligase family fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS gnl|extdb|FAM24227-i1-1.1_000182 1414720.CBYM010000022_gene2216 1.67e-54 176.0 2APNN@1|root,31ES7@2|Bacteria,1V7W5@1239|Firmicutes,24GHR@186801|Clostridia,36IQZ@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000183 883112.HMPREF9707_00537 0.0 1043.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,27DD1@186827|Aerococcaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C gnl|extdb|FAM24227-i1-1.1_000184 1408438.JADD01000016_gene712 1.5e-198 559.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,27DES@186827|Aerococcaceae 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG gnl|extdb|FAM24227-i1-1.1_000185 883112.HMPREF9707_00535 0.0 995.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,27DP7@186827|Aerococcaceae 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 gnl|extdb|FAM24227-i1-1.1_000186 1121871.AUAT01000009_gene980 1.2e-59 192.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,27E1G@186827|Aerococcaceae 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE gnl|extdb|FAM24227-i1-1.1_000187 1408438.JADD01000016_gene715 6.34e-110 330.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,27DW3@186827|Aerococcaceae 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg gnl|extdb|FAM24227-i1-1.1_000188 883112.HMPREF9707_00532 9.89e-107 318.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,27DV7@186827|Aerococcaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yxkD - - - - - - - - - - - DUF2179,YitT_membrane gnl|extdb|FAM24227-i1-1.1_000189 1408438.JADD01000016_gene716 9.97e-124 364.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,27DSP@186827|Aerococcaceae 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase gnl|extdb|FAM24227-i1-1.1_000190 1158602.I590_02817 7.27e-124 363.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,4B0IQ@81852|Enterococcaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N gnl|extdb|FAM24227-i1-1.1_000191 1121871.AUAT01000009_gene975 6.17e-59 184.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,27DZ4@186827|Aerococcaceae 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA gnl|extdb|FAM24227-i1-1.1_000192 1408438.JADD01000016_gene725 0.0 969.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,27DJH@186827|Aerococcaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N gnl|extdb|FAM24227-i1-1.1_000193 883112.HMPREF9707_00527 5.88e-37 127.0 COG1358@1|root,COG1358@2|Bacteria 2|Bacteria J ncRNA processing ylxQ - - ko:K07590,ko:K07742 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L7Ae gnl|extdb|FAM24227-i1-1.1_000194 1408438.JADD01000016_gene727 2.49e-46 151.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,27E2S@186827|Aerococcaceae 91061|Bacilli K Protein of unknown function (DUF448) ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 gnl|extdb|FAM24227-i1-1.1_000195 1408438.JADD01000016_gene728 3.4e-194 554.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,27DDN@186827|Aerococcaceae 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 gnl|extdb|FAM24227-i1-1.1_000196 883112.HMPREF9707_00524 2.72e-84 251.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,27DWK@186827|Aerococcaceae 91061|Bacilli S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C gnl|extdb|FAM24227-i1-1.1_000197 1121871.AUAT01000004_gene1089 2.22e-57 182.0 2A42J@1|root,30SMC@2|Bacteria,1V54W@1239|Firmicutes,4HGI5@91061|Bacilli,27ESU@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000198 1266845.Q783_09980 1.19e-66 209.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_000026 562743.JH976434_gene2000 3.47e-119 350.0 COG1396@1|root,COG1396@2|Bacteria,1V1KD@1239|Firmicutes,4HF5W@91061|Bacilli 91061|Bacilli K this gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - - - - - - - - - - HTH_19,HTH_3 gnl|extdb|FAM24227-i1-1.1_000029 1175629.AJTG01000028_gene24 1.19e-115 342.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HDFE@91061|Bacilli,27DUH@186827|Aerococcaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE gnl|extdb|FAM24227-i1-1.1_000035 1121105.ATXL01000006_gene1340 3.05e-196 563.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,4B0HC@81852|Enterococcaceae 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran gnl|extdb|FAM24227-i1-1.1_000055 1410628.JNKS01000007_gene1430 1.52e-09 57.4 COG2452@1|root,COG2452@2|Bacteria,1TQNJ@1239|Firmicutes,24B79@186801|Clostridia,27M0P@186928|unclassified Lachnospiraceae 186801|Clostridia L Resolvase, N terminal domain - - - ko:K07450 - - - - ko00000 - - - MerR,MerR_1,Resolvase gnl|extdb|FAM24227-i1-1.1_000111 1300150.EMQU_2097 2.11e-24 94.0 COG1813@1|root,COG1813@2|Bacteria,1VEXE@1239|Firmicutes,4HQ33@91061|Bacilli,4B3IJ@81852|Enterococcaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 gnl|extdb|FAM24227-i1-1.1_000123 575594.ACOH01000005_gene1214 1.6e-20 84.3 COG4892@1|root,COG4892@2|Bacteria,1V64Y@1239|Firmicutes,4HNUM@91061|Bacilli,3F812@33958|Lactobacillaceae 91061|Bacilli S Cytochrome B5 - - - - - - - - - - - - Cyt-b5 gnl|extdb|FAM24227-i1-1.1_000135 1511.CLOST_1965 2.16e-111 333.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,24IX8@186801|Clostridia,25TXP@186804|Peptostreptococcaceae 186801|Clostridia C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 gnl|extdb|FAM24227-i1-1.1_000158 1408438.JADD01000009_gene1815 7.23e-63 201.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,27E30@186827|Aerococcaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf gnl|extdb|FAM24227-i1-1.1_000199 1121024.AUCD01000009_gene2025 9.19e-187 530.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,27G7G@186828|Carnobacteriaceae 91061|Bacilli S Peptidase dimerisation domain hipO3 - - ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 gnl|extdb|FAM24227-i1-1.1_000201 883114.HMPREF9709_00992 6.01e-12 67.4 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,24H65@186801|Clostridia,22GDY@1570339|Peptoniphilaceae 186801|Clostridia U Sodium:dicarboxylate symporter family - - - ko:K06956 - - - - ko00000 - - - SDF gnl|extdb|FAM24227-i1-1.1_000202 1158604.I591_00361 1.44e-12 67.8 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,4B221@81852|Enterococcaceae 91061|Bacilli U Sodium:dicarboxylate symporter family - - - ko:K06956 - - - - ko00000 - - - SDF gnl|extdb|FAM24227-i1-1.1_000203 592010.GCWU000182_001831 2.49e-179 511.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,27ENS@186827|Aerococcaceae 91061|Bacilli C Iron-containing alcohol dehydrogenase bdhA - - - - - - - - - - - Fe-ADH gnl|extdb|FAM24227-i1-1.1_000204 1266845.Q783_00355 1.1e-150 438.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,27FGM@186828|Carnobacteriaceae 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer gnl|extdb|FAM24227-i1-1.1_000207 388919.SSA_1065 3.24e-196 583.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1WQMV@1305|Streptococcus sanguinis 91061|Bacilli M Beta-N-acetylhexosaminidase ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Big_2,Glyco_hydro_3,Glyco_hydro_3_C,Gram_pos_anchor,SLH gnl|extdb|FAM24227-i1-1.1_000208 742740.HMPREF9474_04432 1.11e-140 411.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia 186801|Clostridia E orniTHIne cyclodeaminase ocd - 1.5.1.51 ko:K21721 - - - - ko00000,ko01000 - - - OCD_Mu_crystall gnl|extdb|FAM24227-i1-1.1_000209 1139996.OMQ_00897 5.46e-168 487.0 COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,4HB06@91061|Bacilli,4B1RN@81852|Enterococcaceae 91061|Bacilli M Bacterial capsule synthesis protein PGA_cap capA - - ko:K07282 - - - - ko00000 - - - PGA_cap gnl|extdb|FAM24227-i1-1.1_000211 1449343.JQLQ01000002_gene1069 8.62e-222 627.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4H9KS@91061|Bacilli,27FR4@186828|Carnobacteriaceae 91061|Bacilli G phosphotransferase system, EIIB ybbF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090588 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_000212 220668.lp_3523 1.42e-132 385.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 gnl|extdb|FAM24227-i1-1.1_000213 1158602.I590_00012 1.29e-116 348.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4HAHJ@91061|Bacilli,4AZZK@81852|Enterococcaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) yleB - 4.2.1.126 ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - DUF871 gnl|extdb|FAM24227-i1-1.1_000214 1408438.JADD01000032_gene1333 2.5e-16 80.5 COG4529@1|root,COG4529@2|Bacteria,1UZ38@1239|Firmicutes,4HGCU@91061|Bacilli,27EMA@186827|Aerococcaceae 91061|Bacilli S FAD-NAD(P)-binding - - - - - - - - - - - - NAD_binding_9 gnl|extdb|FAM24227-i1-1.1_000215 1408438.JADD01000032_gene1333 1.41e-11 66.6 COG4529@1|root,COG4529@2|Bacteria,1UZ38@1239|Firmicutes,4HGCU@91061|Bacilli,27EMA@186827|Aerococcaceae 91061|Bacilli S FAD-NAD(P)-binding - - - - - - - - - - - - NAD_binding_9 gnl|extdb|FAM24227-i1-1.1_000216 397288.C806_00152 4.79e-168 483.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,27I80@186928|unclassified Lachnospiraceae 186801|Clostridia E Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate dapL - 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_000217 1175629.AJTG01000007_gene1200 2.32e-36 125.0 COG1605@1|root,COG1605@2|Bacteria,1VF5H@1239|Firmicutes,4IPXJ@91061|Bacilli,27EVF@186827|Aerococcaceae 91061|Bacilli E Chorismate mutase type II - - 5.4.99.5 ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 gnl|extdb|FAM24227-i1-1.1_000218 883081.HMPREF9698_00215 2.44e-187 540.0 COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4IEIM@91061|Bacilli,27FQU@186828|Carnobacteriaceae 91061|Bacilli P transporter - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000220 1121871.AUAT01000028_gene1222 1.25e-257 727.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27EJZ@186827|Aerococcaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_000221 1121871.AUAT01000028_gene1223 6.01e-227 657.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,27DGS@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_000222 265729.GS18_0200950 1.9e-09 60.5 COG1846@1|root,COG1846@2|Bacteria,1V7H1@1239|Firmicutes,4HJ7F@91061|Bacilli,1ZG9S@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR gnl|extdb|FAM24227-i1-1.1_000223 883110.HMPREF9260_01507 1.29e-112 332.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,27DYF@186827|Aerococcaceae 91061|Bacilli S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation - - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase gnl|extdb|FAM24227-i1-1.1_000224 883113.HMPREF9708_00843 5.14e-78 239.0 COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,27DY6@186827|Aerococcaceae 91061|Bacilli K HTH domain ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - CBS,HTH_11 gnl|extdb|FAM24227-i1-1.1_000226 1121024.AUCD01000003_gene1376 1.25e-94 287.0 COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,4HBJA@91061|Bacilli,27GR3@186828|Carnobacteriaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS gnl|extdb|FAM24227-i1-1.1_000227 1050201.KB913034_gene1217 5.37e-193 543.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,3VNPZ@526524|Erysipelotrichia 526524|Erysipelotrichia S Bacterial protein of unknown function (DUF871) - - - ko:K09963 - - - - ko00000 - - - DUF871 gnl|extdb|FAM24227-i1-1.1_000228 1121871.AUAT01000005_gene1738 2.44e-218 614.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,27EP1@186827|Aerococcaceae 91061|Bacilli G Phosphotransferase system, EIIC - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC gnl|extdb|FAM24227-i1-1.1_000229 1121871.AUAT01000005_gene1739 8.22e-41 137.0 COG1440@1|root,COG1440@2|Bacteria,1VA8X@1239|Firmicutes,4HQWR@91061|Bacilli,27F53@186827|Aerococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB gnl|extdb|FAM24227-i1-1.1_000231 1050201.KB913034_gene1221 2.07e-39 134.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,3VRUE@526524|Erysipelotrichia 526524|Erysipelotrichia G Psort location Cytoplasmic, score - - - - - - - - - - - - PTS_IIA gnl|extdb|FAM24227-i1-1.1_000232 638301.HMPREF0444_1382 1.85e-144 421.0 COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,4HAYA@91061|Bacilli,27FWE@186828|Carnobacteriaceae 91061|Bacilli H Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK gnl|extdb|FAM24227-i1-1.1_000234 883081.HMPREF9698_01558 6.34e-230 640.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,27FNH@186828|Carnobacteriaceae 91061|Bacilli C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN gnl|extdb|FAM24227-i1-1.1_000235 1139996.OMQ_02116 0.0 1064.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,4AZU3@81852|Enterococcaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD gnl|extdb|FAM24227-i1-1.1_000236 1449335.JQLG01000004_gene555 2.09e-193 556.0 COG0488@1|root,COG0488@2|Bacteria,1TU6J@1239|Firmicutes,4HDY2@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein XK27_10075 - - - - - - - - - - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000237 883110.HMPREF9260_01205 1.61e-72 239.0 COG1705@1|root,COG1705@2|Bacteria,1VH3C@1239|Firmicutes,4I2EF@91061|Bacilli,27EUA@186827|Aerococcaceae 91061|Bacilli NU N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,Glucosaminidase gnl|extdb|FAM24227-i1-1.1_000238 1403313.AXBR01000002_gene4307 1.76e-07 51.6 2E7UF@1|root,3329G@2|Bacteria,1VIA6@1239|Firmicutes,4HNNC@91061|Bacilli,1ZJU7@1386|Bacillus 91061|Bacilli S Bacteriophage A118-like holin, Hol118 - - - - - - - - - - - - Phage_holin_5_1 gnl|extdb|FAM24227-i1-1.1_000239 908337.HMPREF9257_0522 7.4e-19 81.3 2EFPR@1|root,339FR@2|Bacteria,1VHDR@1239|Firmicutes,4HQZ1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000240 1226325.HMPREF1548_02223 3.7e-18 94.0 28M5E@1|root,33F3Q@2|Bacteria,1UPUR@1239|Firmicutes,24X9U@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000241 883110.HMPREF9260_01143 9.04e-39 155.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1VABK@1239|Firmicutes,4HXHW@91061|Bacilli 91061|Bacilli M Bacteriophage peptidoglycan hydrolase - - - - - - - - - - - - Amidase_5 gnl|extdb|FAM24227-i1-1.1_000242 411490.ANACAC_00726 7.63e-07 60.5 COG4926@1|root,COG4926@2|Bacteria,1V80R@1239|Firmicutes,248JI@186801|Clostridia 186801|Clostridia S Phage minor structural protein - - - - - - - - - - - - Prophage_tail gnl|extdb|FAM24227-i1-1.1_000243 1123298.KB904077_gene469 1.46e-22 102.0 COG4722@1|root,COG4722@2|Bacteria,1VHE0@1239|Firmicutes,4HNTT@91061|Bacilli 91061|Bacilli S phage tail - - - - - - - - - - - - Sipho_tail gnl|extdb|FAM24227-i1-1.1_000244 592010.GCWU000182_001494 1.39e-102 369.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,27EB4@186827|Aerococcaceae 91061|Bacilli S Phage-related minor tail protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,Sipho_tail gnl|extdb|FAM24227-i1-1.1_000247 1408438.JADD01000021_gene415 5.23e-56 184.0 2F3XN@1|root,33WPR@2|Bacteria,1VWJB@1239|Firmicutes,4HW6V@91061|Bacilli,27EQA@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000248 592010.GCWU000182_001490 1.59e-17 80.1 2C1EC@1|root,34AZW@2|Bacteria,1W1CE@1239|Firmicutes,4HYD1@91061|Bacilli,27EY7@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000250 1408438.JADD01000021_gene412 4.5e-29 108.0 29353@1|root,2ZQN7@2|Bacteria,1W1QC@1239|Firmicutes,4I13N@91061|Bacilli,27EYK@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000251 1408438.JADD01000021_gene411 6.96e-15 71.2 29HX9@1|root,304UA@2|Bacteria,1TX70@1239|Firmicutes,4I63C@91061|Bacilli,27F05@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000252 565653.EGBG_01970 2.67e-189 536.0 COG4653@1|root,COG4653@2|Bacteria,1U3SF@1239|Firmicutes,4HAF8@91061|Bacilli,4AZ88@81852|Enterococcaceae 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid gnl|extdb|FAM24227-i1-1.1_000253 1408438.JADD01000021_gene409 1.25e-65 209.0 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HM2R@91061|Bacilli,27EV1@186827|Aerococcaceae 91061|Bacilli OU Clp protease - - - - - - - - - - - - CLP_protease gnl|extdb|FAM24227-i1-1.1_000255 592010.GCWU000182_001484 5.18e-120 358.0 COG4695@1|root,COG4695@2|Bacteria,1TRKF@1239|Firmicutes,4HBR6@91061|Bacilli,27EFI@186827|Aerococcaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal gnl|extdb|FAM24227-i1-1.1_000256 592010.GCWU000182_001483 3.2e-206 592.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli 91061|Bacilli L Terminase - - - - - - - - - - - - Terminase_1 gnl|extdb|FAM24227-i1-1.1_000257 1444310.JANV01000001_gene4387 0.000362 44.3 2ECKX@1|root,336IZ@2|Bacteria,1VF3I@1239|Firmicutes,4HNWG@91061|Bacilli,1ZITP@1386|Bacillus 91061|Bacilli S Phage terminase, small subunit - - - - - - - - - - - - Terminase_4 gnl|extdb|FAM24227-i1-1.1_000259 359961.Q2LIE0_9CAUD 5.11e-29 110.0 4QAKA@10239|Viruses,4QYN9@35237|dsDNA viruses no RNA stage,4QR9C@28883|Caudovirales,4QMTC@10699|Siphoviridae 10699|Siphoviridae S DNA-dependent transcription, initiation - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000261 1145276.T479_01580 5.92e-153 457.0 COG0417@1|root,COG0417@2|Bacteria,1TQJQ@1239|Firmicutes,4HF6F@91061|Bacilli 91061|Bacilli L DNA polymerase elongation subunit (Family B) - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000264 638301.HMPREF0444_1525 1.07e-40 137.0 COG1694@1|root,COG1694@2|Bacteria,1VFER@1239|Firmicutes,4HM4N@91061|Bacilli 91061|Bacilli S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG,PRA-PH gnl|extdb|FAM24227-i1-1.1_000267 938278.CAJO01000051_gene795 0.000321 44.3 2919N@1|root,2ZNWQ@2|Bacteria,1W4HX@1239|Firmicutes,256Y7@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000270 592010.GCWU000182_001529 1.13e-24 94.4 COG0695@1|root,COG0695@2|Bacteria,1VK60@1239|Firmicutes,4I3VG@91061|Bacilli,27E7J@186827|Aerococcaceae 91061|Bacilli O Glutaredoxin - - - ko:K06191 - - - - ko00000 - - - Glutaredoxin gnl|extdb|FAM24227-i1-1.1_000272 935836.JAEL01000005_gene2717 5.86e-53 172.0 2DD8C@1|root,2ZH15@2|Bacteria,1V322@1239|Firmicutes,4HPAH@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF669) - - - - - - - - - - - - DUF669 gnl|extdb|FAM24227-i1-1.1_000273 1145276.T479_01565 4.93e-13 65.9 2CB1I@1|root,3330G@2|Bacteria,1VJ8H@1239|Firmicutes,4HNJU@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000275 445335.CBN_1356 2.99e-158 473.0 COG2887@1|root,COG2887@2|Bacteria,1UYIX@1239|Firmicutes,24EMZ@186801|Clostridia,36DIY@31979|Clostridiaceae 186801|Clostridia L AAA domain - - - - - - - - - - - - AAA_24,PDDEXK_1 gnl|extdb|FAM24227-i1-1.1_000277 1423775.BAMN01000011_gene620 3.28e-22 90.9 COG1591@1|root,COG1591@2|Bacteria,1V9FG@1239|Firmicutes,4HSSG@91061|Bacilli 91061|Bacilli L VRR_NUC - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000278 1292035.H476_1032 3.47e-09 60.5 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia 186801|Clostridia L YqaJ viral recombinase family - - - - - - - - - - - - YqaJ gnl|extdb|FAM24227-i1-1.1_000279 1120978.KB894087_gene426 1.4e-17 80.5 COG4570@1|root,COG4570@2|Bacteria,1VFJ9@1239|Firmicutes,4HQ3J@91061|Bacilli,27HJ6@186828|Carnobacteriaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC - - - - - - - - - - - - RusA gnl|extdb|FAM24227-i1-1.1_000285 1499683.CCFF01000016_gene880 3.53e-07 52.4 COG1476@1|root,COG1476@2|Bacteria,1V3HQ@1239|Firmicutes,24CFN@186801|Clostridia,36DDH@31979|Clostridiaceae 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,TPR_7,TPR_8 gnl|extdb|FAM24227-i1-1.1_000287 1235801.C822_00110 3.36e-12 62.0 29PHN@1|root,30AFT@2|Bacteria,1U6KU@1239|Firmicutes,4IGDM@91061|Bacilli,3F84C@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000288 1033738.CAEP01000156_gene4223 6.35e-12 65.9 COG1396@1|root,COG1396@2|Bacteria,1VEP9@1239|Firmicutes,4HPCR@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_26,HTH_3 gnl|extdb|FAM24227-i1-1.1_000289 883081.HMPREF9698_01139 1.52e-29 110.0 COG2856@1|root,COG2856@2|Bacteria,1U5SF@1239|Firmicutes,4HRI2@91061|Bacilli,27HNV@186828|Carnobacteriaceae 91061|Bacilli E Zn peptidase - - - - - - - - - - - - Peptidase_M78 gnl|extdb|FAM24227-i1-1.1_000291 1231336.L248_2109 2.77e-41 153.0 2DXEF@1|root,344NR@2|Bacteria,1W0A3@1239|Firmicutes,4HY87@91061|Bacilli,3F7DE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000293 1408438.JADD01000021_gene373 1.16e-87 276.0 COG0582@1|root,COG0582@2|Bacteria,1V15G@1239|Firmicutes,4HK3H@91061|Bacilli,27DZU@186827|Aerococcaceae 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase gnl|extdb|FAM24227-i1-1.1_000294 883112.HMPREF9707_00427 1.05e-52 166.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,27E1C@186827|Aerococcaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 gnl|extdb|FAM24227-i1-1.1_000295 1408438.JADD01000039_gene1399 2.32e-35 124.0 COG2868@1|root,COG2868@2|Bacteria,1TVNY@1239|Firmicutes,4I3RJ@91061|Bacilli,27E9P@186827|Aerococcaceae 91061|Bacilli J Cysteine protease Prp - - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp gnl|extdb|FAM24227-i1-1.1_000296 1408438.JADD01000039_gene1398 2.21e-57 179.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,27DZT@186827|Aerococcaceae 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p gnl|extdb|FAM24227-i1-1.1_000297 1122228.AQXR01000008_gene660 7.73e-66 208.0 COG4493@1|root,COG4493@2|Bacteria,2H4MN@201174|Actinobacteria,4D26J@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1054) - - - - - - - - - - - - DUF1054 gnl|extdb|FAM24227-i1-1.1_000298 221027.JO40_08950 1.46e-116 346.0 COG2355@1|root,COG2355@2|Bacteria,2J8PX@203691|Spirochaetes 203691|Spirochaetes E PFAM peptidase M19 renal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 gnl|extdb|FAM24227-i1-1.1_000299 1408438.JADD01000039_gene1396 4.16e-129 388.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,27DKR@186827|Aerococcaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 gnl|extdb|FAM24227-i1-1.1_000300 1408438.JADD01000039_gene1395 2.19e-72 229.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HIA7@91061|Bacilli 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins - - - - - - - - - - - - SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_000301 1408438.JADD01000009_gene1816 7.22e-85 261.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HIA7@91061|Bacilli 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins - - - - - - - - - - - - SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_000302 883112.HMPREF9707_00423 2.68e-72 223.0 COG2891@1|root,COG2891@2|Bacteria,1V5MH@1239|Firmicutes,4I62S@91061|Bacilli,27EQI@186827|Aerococcaceae 91061|Bacilli M rod shape-determining protein MreD - - - - - - - - - - - - MreD gnl|extdb|FAM24227-i1-1.1_000303 883112.HMPREF9707_00422 3.84e-144 412.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,27DDE@186827|Aerococcaceae 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC gnl|extdb|FAM24227-i1-1.1_000304 592010.GCWU000182_001295 9.14e-153 439.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,27DN7@186827|Aerococcaceae 91061|Bacilli D MreB/Mbl protein - - - - - - - - - - - - MreB_Mbl gnl|extdb|FAM24227-i1-1.1_000305 1229520.ADIAL_1538 5.67e-214 605.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,27G1P@186828|Carnobacteriaceae 91061|Bacilli C Aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 ko:K00128,ko:K00135 ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh gnl|extdb|FAM24227-i1-1.1_000306 1408438.JADD01000039_gene1391 6.55e-36 122.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,27E70@186827|Aerococcaceae 91061|Bacilli K Cold shock protein cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD gnl|extdb|FAM24227-i1-1.1_000307 883112.HMPREF9707_00419 4.32e-110 322.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,27DS8@186827|Aerococcaceae 91061|Bacilli E RadC-like JAB domain radC - - ko:K03630 - - - - ko00000 - - - RadC gnl|extdb|FAM24227-i1-1.1_000308 883113.HMPREF9708_00138 1.01e-148 437.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,27DMJ@186827|Aerococcaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M gnl|extdb|FAM24227-i1-1.1_000309 1408438.JADD01000039_gene1388 0.0 1413.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,27DBT@186827|Aerococcaceae 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 gnl|extdb|FAM24227-i1-1.1_000311 1408438.JADD01000015_gene758 0.0 904.0 COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,4HBAN@91061|Bacilli,27EC5@186827|Aerococcaceae 91061|Bacilli G Firmicute fructose-1,6-bisphosphatase fbp - 3.1.3.11 ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_2 gnl|extdb|FAM24227-i1-1.1_000312 1121871.AUAT01000041_gene714 1.98e-74 227.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,27EQN@186827|Aerococcaceae 91061|Bacilli O Redoxin tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin gnl|extdb|FAM24227-i1-1.1_000313 1121871.AUAT01000041_gene713 3.61e-193 547.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,27DQ9@186827|Aerococcaceae 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI gnl|extdb|FAM24227-i1-1.1_000314 1408438.JADD01000018_gene677 1.74e-142 416.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,27DMH@186827|Aerococcaceae 91061|Bacilli E Aminotransferase class-V iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 gnl|extdb|FAM24227-i1-1.1_000315 883112.HMPREF9707_00414 2.02e-256 721.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,27DJ1@186827|Aerococcaceae 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA gnl|extdb|FAM24227-i1-1.1_000316 883112.HMPREF9707_00706 1.19e-136 398.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,27DNT@186827|Aerococcaceae 91061|Bacilli S Basic membrane protein tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp gnl|extdb|FAM24227-i1-1.1_000317 1408438.JADD01000018_gene675 4.07e-119 343.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,27DIT@186827|Aerococcaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 gnl|extdb|FAM24227-i1-1.1_000318 1408438.JADD01000018_gene674 2.52e-97 289.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HG2F@91061|Bacilli,27ES4@186827|Aerococcaceae 91061|Bacilli E ATPases associated with a variety of cellular activities - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000319 1408438.JADD01000018_gene673 1.17e-212 602.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,27EC0@186827|Aerococcaceae 91061|Bacilli P Bacterial periplasmic substrate-binding proteins yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000320 1408438.JADD01000018_gene673 2.07e-79 251.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,27EC0@186827|Aerococcaceae 91061|Bacilli P Bacterial periplasmic substrate-binding proteins yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000321 1408438.JADD01000018_gene673 4.17e-79 253.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,27EC0@186827|Aerococcaceae 91061|Bacilli P Bacterial periplasmic substrate-binding proteins yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000322 883112.HMPREF9707_00412 1.14e-81 250.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,27DY1@186827|Aerococcaceae 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 gnl|extdb|FAM24227-i1-1.1_000323 1121871.AUAT01000014_gene413 5.68e-05 47.0 28S14@1|root,2ZED0@2|Bacteria,1W5DQ@1239|Firmicutes,4I02A@91061|Bacilli,27F1W@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000324 592010.GCWU000182_001267 1.44e-56 184.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,27E2H@186827|Aerococcaceae 91061|Bacilli L NUDIX domain nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX gnl|extdb|FAM24227-i1-1.1_000325 592010.GCWU000182_001266 1.9e-50 178.0 COG4915@1|root,COG4915@2|Bacteria,1VB0U@1239|Firmicutes,4HMAQ@91061|Bacilli,27E4X@186827|Aerococcaceae 91061|Bacilli S 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - - - - - - - - - - Halogen_Hydrol gnl|extdb|FAM24227-i1-1.1_000326 592010.GCWU000182_001265 2.04e-185 528.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4H9Z6@91061|Bacilli,27DJ6@186827|Aerococcaceae 91061|Bacilli P Toxic anion resistance protein TelA yaaN - - - - - - - - - - - TelA gnl|extdb|FAM24227-i1-1.1_000327 1540257.JQMW01000011_gene2236 4.42e-16 86.3 COG1668@1|root,COG1668@2|Bacteria,1UKFI@1239|Firmicutes,25FVI@186801|Clostridia,36V02@31979|Clostridiaceae 186801|Clostridia CP ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 gnl|extdb|FAM24227-i1-1.1_000328 1121105.ATXL01000024_gene2062 2.38e-26 116.0 COG0842@1|root,COG0842@2|Bacteria,1VIDU@1239|Firmicutes,4HWNT@91061|Bacilli 91061|Bacilli V ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_3 gnl|extdb|FAM24227-i1-1.1_000329 1121105.ATXL01000024_gene2061 1.12e-119 353.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,4B0KG@81852|Enterococcaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000330 638301.HMPREF0444_1914 8.39e-72 224.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHIC@91061|Bacilli,27HHI@186828|Carnobacteriaceae 91061|Bacilli K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg gnl|extdb|FAM24227-i1-1.1_000331 1128398.Curi_c26210 4.1e-44 160.0 COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,269X9@186813|unclassified Clostridiales 186801|Clostridia T Psort location CytoplasmicMembrane, score - - - - - - - - - - - - HATPase_c,HisKA_3 gnl|extdb|FAM24227-i1-1.1_000332 1121871.AUAT01000014_gene409 0.0 1398.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,27DBN@186827|Aerococcaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS gnl|extdb|FAM24227-i1-1.1_000333 1121871.AUAT01000014_gene408 1.92e-71 228.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,27E4A@186827|Aerococcaceae 91061|Bacilli D DivIVA protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA gnl|extdb|FAM24227-i1-1.1_000334 1121871.AUAT01000014_gene407 1.18e-117 344.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,27DTV@186827|Aerococcaceae 91061|Bacilli S S4 RNA-binding domain ylmH - - - - - - - - - - - S4 gnl|extdb|FAM24227-i1-1.1_000335 883110.HMPREF9260_00096 1.66e-32 115.0 COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli,27E65@186827|Aerococcaceae 91061|Bacilli S YGGT family ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT gnl|extdb|FAM24227-i1-1.1_000336 883112.HMPREF9707_00402 4.66e-219 615.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,27DFK@186827|Aerococcaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin gnl|extdb|FAM24227-i1-1.1_000337 1121871.AUAT01000014_gene404 1.07e-232 655.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,27DMD@186827|Aerococcaceae 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA gnl|extdb|FAM24227-i1-1.1_000338 883112.HMPREF9707_00400 3.17e-57 200.0 COG1589@1|root,COG1589@2|Bacteria,1VHEY@1239|Firmicutes,4HQCD@91061|Bacilli,27E6X@186827|Aerococcaceae 91061|Bacilli D cell division protein divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 gnl|extdb|FAM24227-i1-1.1_000340 883112.HMPREF9707_00398 6.96e-187 536.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,27DRF@186827|Aerococcaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M gnl|extdb|FAM24227-i1-1.1_000342 1121871.AUAT01000014_gene399 6.29e-217 615.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,27DS3@186827|Aerococcaceae 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M gnl|extdb|FAM24227-i1-1.1_000343 592010.GCWU000182_000289 1.09e-206 594.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,27DI8@186827|Aerococcaceae 91061|Bacilli M Penicillin-binding protein, transpeptidase domain protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase gnl|extdb|FAM24227-i1-1.1_000345 592010.GCWU000182_000291 1.14e-156 447.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,27DJE@186827|Aerococcaceae 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 gnl|extdb|FAM24227-i1-1.1_000346 883112.HMPREF9707_00392 4.09e-86 254.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,27DWE@186827|Aerococcaceae 91061|Bacilli K MraZ protein, putative antitoxin-like mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ gnl|extdb|FAM24227-i1-1.1_000347 883113.HMPREF9708_00167 7.01e-37 129.0 2C91D@1|root,2ZRD3@2|Bacteria,1W42U@1239|Firmicutes,4HRF7@91061|Bacilli,27EZG@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000348 592010.GCWU000182_000294 3.82e-19 79.7 29HX8@1|root,3044B@2|Bacteria,1VA7I@1239|Firmicutes,4I4NQ@91061|Bacilli,27F01@186827|Aerococcaceae 91061|Bacilli S DNA-directed RNA polymerase subunit beta - - - - - - - - - - - - EpuA gnl|extdb|FAM24227-i1-1.1_000349 592010.GCWU000182_000295 1.31e-158 455.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,27DFD@186827|Aerococcaceae 91061|Bacilli D MreB/Mbl protein mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl gnl|extdb|FAM24227-i1-1.1_000350 883112.HMPREF9707_00388 1.36e-245 682.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,27DMR@186827|Aerococcaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase gnl|extdb|FAM24227-i1-1.1_000351 908337.HMPREF9257_1363 6.64e-13 64.7 28Z53@1|root,2ZKXE@2|Bacteria,1W30G@1239|Firmicutes,4I100@91061|Bacilli,27F0A@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1146) - - - - - - - - - - - - DUF1146 gnl|extdb|FAM24227-i1-1.1_000200 1121024.AUCD01000009_gene2026 1.63e-190 545.0 COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,4H9P7@91061|Bacilli,27FPP@186828|Carnobacteriaceae 91061|Bacilli S C4-dicarboxylate anaerobic carrier - - - - - - - - - - - - DcuC gnl|extdb|FAM24227-i1-1.1_000225 883113.HMPREF9708_00844 0.0 1081.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4HBU2@91061|Bacilli,27EBQ@186827|Aerococcaceae 91061|Bacilli G Pyruvate phosphate dikinase, PEP/pyruvate binding domain ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N gnl|extdb|FAM24227-i1-1.1_000258 592010.GCWU000182_001481 3.87e-35 123.0 COG1403@1|root,COG1403@2|Bacteria,1VKF1@1239|Firmicutes,4IRTY@91061|Bacilli,27EVC@186827|Aerococcaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - HNH gnl|extdb|FAM24227-i1-1.1_000260 1145276.T479_01590 1.83e-226 649.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,3IYPQ@400634|Lysinibacillus 91061|Bacilli S DNA primase - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,RepB_primase,Toprim_4,zf-CHC2 gnl|extdb|FAM24227-i1-1.1_000269 1121871.AUAT01000002_gene1368 3.97e-21 86.3 2C2JW@1|root,3316C@2|Bacteria,1VFRB@1239|Firmicutes,4HPUN@91061|Bacilli 91061|Bacilli S Domain of Unknown Function (DUF1599) - - - - - - - - - - - - DUF1599 gnl|extdb|FAM24227-i1-1.1_000310 866775.HMPREF9243_1368 5.59e-110 323.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,27DG5@186827|Aerococcaceae 91061|Bacilli K Sir2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 gnl|extdb|FAM24227-i1-1.1_000339 883112.HMPREF9707_00399 7.34e-160 460.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,27DNY@186827|Aerococcaceae 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 gnl|extdb|FAM24227-i1-1.1_000341 883112.HMPREF9707_00397 2.5e-146 421.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,27DJY@186827|Aerococcaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 gnl|extdb|FAM24227-i1-1.1_000352 592010.GCWU000182_000060 3.85e-72 224.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,27E3X@186827|Aerococcaceae 91061|Bacilli I Phosphate acyltransferases plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase gnl|extdb|FAM24227-i1-1.1_000353 592010.GCWU000182_000059 9.75e-75 235.0 COG3823@1|root,COG3823@2|Bacteria,1V979@1239|Firmicutes,4HK8R@91061|Bacilli,27EPU@186827|Aerococcaceae 91061|Bacilli O Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 gnl|extdb|FAM24227-i1-1.1_000354 1408438.JADD01000022_gene56 2.7e-260 715.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,27DK2@186827|Aerococcaceae 91061|Bacilli J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT gnl|extdb|FAM24227-i1-1.1_000355 1408438.JADD01000022_gene57 1.38e-45 150.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,27E75@186827|Aerococcaceae 91061|Bacilli U Preprotein translocase subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC gnl|extdb|FAM24227-i1-1.1_000356 908337.HMPREF9257_0989 3.93e-169 483.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,27DT6@186827|Aerococcaceae 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH gnl|extdb|FAM24227-i1-1.1_000357 1121871.AUAT01000029_gene996 2.2e-116 341.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli,27DS6@186827|Aerococcaceae 91061|Bacilli P ZIP Zinc transporter zupT - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip gnl|extdb|FAM24227-i1-1.1_000358 592010.GCWU000182_000265 2.66e-190 542.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,27DST@186827|Aerococcaceae 91061|Bacilli K DRTGG domain protein ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 gnl|extdb|FAM24227-i1-1.1_000359 1408438.JADD01000022_gene60 4.14e-117 348.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,27DM7@186827|Aerococcaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 gnl|extdb|FAM24227-i1-1.1_000360 908337.HMPREF9257_0985 1.15e-202 577.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,27DD0@186827|Aerococcaceae 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N gnl|extdb|FAM24227-i1-1.1_000361 908337.HMPREF9257_0984 3.26e-192 548.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,27DET@186827|Aerococcaceae 91061|Bacilli L helicase superfamily c-terminal domain cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C gnl|extdb|FAM24227-i1-1.1_000362 883110.HMPREF9260_00445 1.12e-27 117.0 2E9SU@1|root,333YY@2|Bacteria,1VHNB@1239|Firmicutes,4HPAE@91061|Bacilli,27E64@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1189) - - - - - - - - - - - - DUF1189 gnl|extdb|FAM24227-i1-1.1_000363 1408438.JADD01000003_gene193 0.0 942.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HBW6@91061|Bacilli,27DJX@186827|Aerococcaceae 91061|Bacilli S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO gnl|extdb|FAM24227-i1-1.1_000364 883112.HMPREF9707_00723 0.0 1030.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,27DGP@186827|Aerococcaceae 91061|Bacilli M Penicillin-binding protein, transpeptidase domain protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase gnl|extdb|FAM24227-i1-1.1_000365 1408438.JADD01000003_gene195 5.63e-43 150.0 COG1559@1|root,COG1559@2|Bacteria,1VZ75@1239|Firmicutes,4HRAC@91061|Bacilli 91061|Bacilli S periplasmic solute-binding protein - - - - - - - - - - - - YceG gnl|extdb|FAM24227-i1-1.1_000366 883112.HMPREF9707_00720 4.28e-32 117.0 2ENTI@1|root,33GEQ@2|Bacteria,1VMV8@1239|Firmicutes,4HRRF@91061|Bacilli,27EVB@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_23 gnl|extdb|FAM24227-i1-1.1_000367 883113.HMPREF9708_01321 2.63e-26 96.7 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,27F1X@186827|Aerococcaceae 91061|Bacilli J Ribosomal protein L33 rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 gnl|extdb|FAM24227-i1-1.1_000368 1408438.JADD01000003_gene197 1.6e-45 156.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,27E68@186827|Aerococcaceae 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig gnl|extdb|FAM24227-i1-1.1_000369 883112.HMPREF9707_00716 5.32e-72 226.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,27E3J@186827|Aerococcaceae 91061|Bacilli S Rhomboid family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 gnl|extdb|FAM24227-i1-1.1_000370 1408438.JADD01000003_gene200 6.3e-50 162.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,27E73@186827|Aerococcaceae 91061|Bacilli P Rhodanese Homology Domain yqhL - - - - - - - - - - - Rhodanese gnl|extdb|FAM24227-i1-1.1_000372 592010.GCWU000182_001318 1.51e-265 736.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,27DGC@186827|Aerococcaceae 91061|Bacilli H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 gnl|extdb|FAM24227-i1-1.1_000373 1121871.AUAT01000029_gene1011 2.24e-145 412.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,27DTG@186827|Aerococcaceae 91061|Bacilli T Response regulator receiver domain protein csrR - - - - - - - - - - - Response_reg,Trans_reg_C gnl|extdb|FAM24227-i1-1.1_000374 883112.HMPREF9707_00710 1.85e-193 555.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,27DE6@186827|Aerococcaceae 91061|Bacilli T ATPase histidine kinase DNA gyrase B HSP90 domain protein arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA gnl|extdb|FAM24227-i1-1.1_000375 1408438.JADD01000003_gene203 1.98e-127 372.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,27DM3@186827|Aerococcaceae 91061|Bacilli U Membrane protein insertase, YidC Oxa1 family yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP gnl|extdb|FAM24227-i1-1.1_000376 1121871.AUAT01000020_gene3 3.29e-27 102.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,27E9K@186827|Aerococcaceae 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase gnl|extdb|FAM24227-i1-1.1_000377 883112.HMPREF9707_00707 0.0 952.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,27DEW@186827|Aerococcaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma gnl|extdb|FAM24227-i1-1.1_000378 883112.HMPREF9707_00706 9.41e-194 543.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,27DNT@186827|Aerococcaceae 91061|Bacilli S Basic membrane protein tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp gnl|extdb|FAM24227-i1-1.1_000380 908337.HMPREF9257_0966 6.02e-264 736.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,27DRK@186827|Aerococcaceae 91061|Bacilli S ATPases associated with a variety of cellular activities mglA - 3.6.3.17 ko:K02056,ko:K06400 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000382 883112.HMPREF9707_00702 7.72e-165 468.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,27DC3@186827|Aerococcaceae 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 gnl|extdb|FAM24227-i1-1.1_000383 883112.HMPREF9707_00701 1.02e-96 296.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,27EM1@186827|Aerococcaceae 91061|Bacilli S Helix-turn-helix domain ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 gnl|extdb|FAM24227-i1-1.1_000385 1408438.JADD01000003_gene214 5.33e-146 428.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,27DMV@186827|Aerococcaceae 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth gnl|extdb|FAM24227-i1-1.1_000386 1408438.JADD01000003_gene215 1.79e-202 566.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,27DE5@186827|Aerococcaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA gnl|extdb|FAM24227-i1-1.1_000387 1408438.JADD01000003_gene216 4.71e-251 703.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,27DE2@186827|Aerococcaceae 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 gnl|extdb|FAM24227-i1-1.1_000388 592010.GCWU000182_001309 4.56e-104 310.0 COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,27EKM@186827|Aerococcaceae 91061|Bacilli S YmdB-like protein ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - ko:K02029,ko:K02030,ko:K09769 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - YmdB gnl|extdb|FAM24227-i1-1.1_000389 592010.GCWU000182_001310 0.0 1013.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,27DKC@186827|Aerococcaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V gnl|extdb|FAM24227-i1-1.1_000390 908337.HMPREF9257_0957 5.18e-234 670.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,27DGI@186827|Aerococcaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C gnl|extdb|FAM24227-i1-1.1_000391 592010.GCWU000182_001312 1e-69 213.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,27DYH@186827|Aerococcaceae 91061|Bacilli O Peptide methionine sulfoxide reductase MsrB msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR gnl|extdb|FAM24227-i1-1.1_000392 1158602.I590_03752 2.34e-74 225.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,4B2CI@81852|Enterococcaceae 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR gnl|extdb|FAM24227-i1-1.1_000393 592010.GCWU000182_001313 2.31e-77 237.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,27E4N@186827|Aerococcaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N gnl|extdb|FAM24227-i1-1.1_000394 1121871.AUAT01000020_gene20 5.59e-170 483.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,27DPG@186827|Aerococcaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N gnl|extdb|FAM24227-i1-1.1_000395 883112.HMPREF9707_00691 4.71e-198 554.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,27DMU@186827|Aerococcaceae 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth gnl|extdb|FAM24227-i1-1.1_000396 1408438.JADD01000020_gene1457 0.0 1139.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,27DN5@186827|Aerococcaceae 91061|Bacilli L DNA polymerase alpha chain like domain dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon gnl|extdb|FAM24227-i1-1.1_000399 883113.HMPREF9708_00015 3.06e-108 322.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,27DUA@186827|Aerococcaceae 91061|Bacilli S Ribosomal protein S1-like RNA-binding domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 gnl|extdb|FAM24227-i1-1.1_000400 1408438.JADD01000020_gene1461 3.78e-131 381.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,27DIH@186827|Aerococcaceae 91061|Bacilli D Phage integrase, N-terminal SAM-like domain xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase gnl|extdb|FAM24227-i1-1.1_000401 883112.HMPREF9707_00685 8.43e-226 628.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,27DQB@186827|Aerococcaceae 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme gnl|extdb|FAM24227-i1-1.1_000402 592010.GCWU000182_000182 3.47e-138 396.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,27EE5@186827|Aerococcaceae 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 gnl|extdb|FAM24227-i1-1.1_000403 1121871.AUAT01000020_gene29 8.28e-39 134.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,27E7N@186827|Aerococcaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 gnl|extdb|FAM24227-i1-1.1_000404 592010.GCWU000182_000180 6.49e-82 253.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,27DV4@186827|Aerococcaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA gnl|extdb|FAM24227-i1-1.1_000405 592010.GCWU000182_000179 7.95e-87 261.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,27E0V@186827|Aerococcaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB gnl|extdb|FAM24227-i1-1.1_000406 883113.HMPREF9708_00007 5.61e-115 335.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,27DF1@186827|Aerococcaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 gnl|extdb|FAM24227-i1-1.1_000407 1121871.AUAT01000020_gene33 2.83e-67 212.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,27E3E@186827|Aerococcaceae 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt gnl|extdb|FAM24227-i1-1.1_000408 1121871.AUAT01000020_gene34 9.25e-37 135.0 COG1388@1|root,COG1388@2|Bacteria,1U09Z@1239|Firmicutes,4IE5Q@91061|Bacilli,27E6H@186827|Aerococcaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM gnl|extdb|FAM24227-i1-1.1_000409 1408438.JADD01000020_gene1469 5.3e-81 248.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,27DYR@186827|Aerococcaceae 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin gnl|extdb|FAM24227-i1-1.1_000410 1408438.JADD01000020_gene1470 1.68e-221 622.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,27DC8@186827|Aerococcaceae 91061|Bacilli J ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 gnl|extdb|FAM24227-i1-1.1_000411 592010.GCWU000182_000172 5.17e-256 709.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,27DCN@186827|Aerococcaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 gnl|extdb|FAM24227-i1-1.1_000412 1408438.JADD01000020_gene1472 3.08e-50 160.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,27E27@186827|Aerococcaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding gnl|extdb|FAM24227-i1-1.1_000413 1408438.JADD01000020_gene1473 8e-39 152.0 2E8RS@1|root,3332R@2|Bacteria,1VGK1@1239|Firmicutes,4HPQR@91061|Bacilli,27E5Q@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - ANAPC3 gnl|extdb|FAM24227-i1-1.1_000414 1121871.AUAT01000004_gene1144 6.82e-59 189.0 COG5582@1|root,COG5582@2|Bacteria,1V5KV@1239|Firmicutes,4HEE0@91061|Bacilli,27E2E@186827|Aerococcaceae 91061|Bacilli S UPF0302 domain ypiB - - - - - - - - - - - IDEAL,UPF0302 gnl|extdb|FAM24227-i1-1.1_000415 883112.HMPREF9707_00666 1.34e-135 401.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,27DGM@186827|Aerococcaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 gnl|extdb|FAM24227-i1-1.1_000416 908337.HMPREF9257_0931 7.84e-115 377.0 COG0847@1|root,COG0847@2|Bacteria,1UKF3@1239|Firmicutes,4ITIP@91061|Bacilli,27E1Z@186827|Aerococcaceae 91061|Bacilli L EXOIII - - - - - - - - - - - - RNase_T gnl|extdb|FAM24227-i1-1.1_000417 1408438.JADD01000020_gene1477 3.46e-55 177.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,27E9T@186827|Aerococcaceae 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY gnl|extdb|FAM24227-i1-1.1_000418 883112.HMPREF9707_00663 4.91e-272 749.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,27DQC@186827|Aerococcaceae 91061|Bacilli J tRNA synthetases class II (D, K and N) asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon gnl|extdb|FAM24227-i1-1.1_000419 883112.HMPREF9707_00662 2.12e-78 243.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,27E26@186827|Aerococcaceae 91061|Bacilli L Replication initiation and membrane attachment dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 gnl|extdb|FAM24227-i1-1.1_000420 883103.HMPREF9703_01268 6.94e-77 236.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,27FR7@186828|Carnobacteriaceae 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD gnl|extdb|FAM24227-i1-1.1_000421 1232430.CAVG010000062_gene606 3.26e-42 145.0 COG2963@1|root,COG2963@2|Bacteria,1V35U@1239|Firmicutes,4HHRN@91061|Bacilli,4GZFK@90964|Staphylococcaceae 91061|Bacilli L Helix-turn-helix domain - - - ko:K07483,ko:K07497 - - - - ko00000 - - - HTH_28,HTH_Tnp_1 gnl|extdb|FAM24227-i1-1.1_000422 1284708.HMPREF1634_08815 2.17e-113 334.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,2487W@186801|Clostridia,3WDSW@538999|Clostridiales incertae sedis 186801|Clostridia L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 gnl|extdb|FAM24227-i1-1.1_000423 1408438.JADD01000004_gene1059 4.78e-62 198.0 COG4684@1|root,COG4684@2|Bacteria,1VB4T@1239|Firmicutes,4HMUC@91061|Bacilli,27E4R@186827|Aerococcaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt gnl|extdb|FAM24227-i1-1.1_000424 1122147.AUEH01000045_gene2970 1.88e-05 52.4 2E7NX@1|root,33B9D@2|Bacteria,1VPN2@1239|Firmicutes,4HS0V@91061|Bacilli,3F7ZV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000425 1121871.AUAT01000004_gene1137 0.0 1100.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,27DGH@186827|Aerococcaceae 91061|Bacilli M Penicillin-binding protein, 1A family ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 gnl|extdb|FAM24227-i1-1.1_000426 1121871.AUAT01000004_gene1136 2.56e-90 270.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,27DWF@186827|Aerococcaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU gnl|extdb|FAM24227-i1-1.1_000427 908337.HMPREF9257_0924 1.66e-214 603.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,27DDY@186827|Aerococcaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N gnl|extdb|FAM24227-i1-1.1_000428 883112.HMPREF9707_00658 2.79e-232 647.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,27DNP@186827|Aerococcaceae 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX gnl|extdb|FAM24227-i1-1.1_000429 592010.GCWU000182_001359 1.8e-91 272.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,27DKX@186827|Aerococcaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 gnl|extdb|FAM24227-i1-1.1_000430 592010.GCWU000182_001360 2.76e-189 538.0 COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,27EHK@186827|Aerococcaceae 91061|Bacilli S Vacuole effluxer Atg22 like yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 gnl|extdb|FAM24227-i1-1.1_000431 1408438.JADD01000019_gene860 7.5e-214 616.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,27DRV@186827|Aerococcaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 gnl|extdb|FAM24227-i1-1.1_000379 883112.HMPREF9707_00706 9.89e-160 456.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,27DNT@186827|Aerococcaceae 91061|Bacilli S Basic membrane protein tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp gnl|extdb|FAM24227-i1-1.1_000381 883112.HMPREF9707_00703 1.68e-182 516.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,27DCR@186827|Aerococcaceae 91061|Bacilli S branched-chain amino acid ABC transporter, permease protein mglC - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 gnl|extdb|FAM24227-i1-1.1_000384 883112.HMPREF9707_00700 4.87e-89 266.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,27DWR@186827|Aerococcaceae 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf gnl|extdb|FAM24227-i1-1.1_000397 883112.HMPREF9707_00689 3.95e-185 520.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,27DC5@186827|Aerococcaceae 91061|Bacilli G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK gnl|extdb|FAM24227-i1-1.1_000398 1408438.JADD01000020_gene1459 0.0 882.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,27DDS@186827|Aerococcaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C gnl|extdb|FAM24227-i1-1.1_000432 1408438.JADD01000019_gene861 7.59e-232 642.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,27DSH@186827|Aerococcaceae 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 gnl|extdb|FAM24227-i1-1.1_000433 592010.GCWU000182_000734 1.14e-96 290.0 COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,4HAFM@91061|Bacilli,27ET4@186827|Aerococcaceae 91061|Bacilli P ATPases associated with a variety of cellular activities - - - ko:K15555 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.2 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000434 592010.GCWU000182_000735 4.82e-149 429.0 COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBR9@91061|Bacilli,27E5Z@186827|Aerococcaceae 91061|Bacilli P NMT1/THI5 like M1-596 - - - - - - - - - - - NMT1 gnl|extdb|FAM24227-i1-1.1_000435 592010.GCWU000182_000736 9.35e-120 350.0 COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HARZ@91061|Bacilli,27F4T@186827|Aerococcaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component tauC - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000436 1423734.JCM14202_3570 9e-23 91.3 COG0011@1|root,COG0011@2|Bacteria,1VC4R@1239|Firmicutes,4HSQA@91061|Bacilli,3F7GK@33958|Lactobacillaceae 91061|Bacilli S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP gnl|extdb|FAM24227-i1-1.1_000437 592010.GCWU000182_000914 4.77e-236 659.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,27DCB@186827|Aerococcaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N gnl|extdb|FAM24227-i1-1.1_000438 592010.GCWU000182_000913 7.71e-45 148.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,27E25@186827|Aerococcaceae 91061|Bacilli K Transcriptional regulator, MerR family glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 gnl|extdb|FAM24227-i1-1.1_000439 592010.GCWU000182_000915 4.72e-88 273.0 COG4990@1|root,COG4990@2|Bacteria,1VDCP@1239|Firmicutes,4HNSJ@91061|Bacilli,27EES@186827|Aerococcaceae 91061|Bacilli S Papain-like cysteine protease AvrRpt2 - - - - - - - - - - - - Amidase_3,Peptidase_C39_2,SH3_3 gnl|extdb|FAM24227-i1-1.1_000440 592010.GCWU000182_000917 4.16e-270 744.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,27EH6@186827|Aerococcaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt gnl|extdb|FAM24227-i1-1.1_000443 1408438.JADD01000030_gene1266 2.81e-230 645.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,27DDC@186827|Aerococcaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C gnl|extdb|FAM24227-i1-1.1_000444 1121871.AUAT01000005_gene1780 3.1e-66 205.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,27DZY@186827|Aerococcaceae 91061|Bacilli J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N gnl|extdb|FAM24227-i1-1.1_000445 883112.HMPREF9707_00902 1.09e-279 788.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,27DKI@186827|Aerococcaceae 91061|Bacilli T DHHA1 domain protein yybT - - - - - - - - - - - DHH,DHHA1 gnl|extdb|FAM24227-i1-1.1_000446 1408438.JADD01000027_gene923 5.7e-44 143.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,27E3W@186827|Aerococcaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 gnl|extdb|FAM24227-i1-1.1_000448 883112.HMPREF9707_00899 1.3e-50 161.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,27E1S@186827|Aerococcaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 gnl|extdb|FAM24227-i1-1.1_000449 1408438.JADD01000005_gene1224 2.45e-173 493.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,27EJD@186827|Aerococcaceae 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 gnl|extdb|FAM24227-i1-1.1_000450 903814.ELI_0730 1.93e-153 445.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,25VFK@186806|Eubacteriaceae 186801|Clostridia C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family pdxB - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C gnl|extdb|FAM24227-i1-1.1_000451 1121871.AUAT01000005_gene1774 0.0 1214.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,27DGZ@186827|Aerococcaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV gnl|extdb|FAM24227-i1-1.1_000452 1121871.AUAT01000005_gene1773 0.0 1038.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,27DRH@186827|Aerococcaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim gnl|extdb|FAM24227-i1-1.1_000453 1121871.AUAT01000005_gene1772 5.67e-157 452.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,27DHM@186827|Aerococcaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N gnl|extdb|FAM24227-i1-1.1_000454 1121871.AUAT01000005_gene1771 3.13e-25 95.9 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,27E8X@186827|Aerococcaceae 91061|Bacilli S S4 domain protein YaaA yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 gnl|extdb|FAM24227-i1-1.1_000455 908337.HMPREF9257_0782 3.46e-168 482.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,27DNM@186827|Aerococcaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 gnl|extdb|FAM24227-i1-1.1_000456 883112.HMPREF9707_00892 7.56e-226 633.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,27DHF@186827|Aerococcaceae 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N gnl|extdb|FAM24227-i1-1.1_000457 883113.HMPREF9708_00689 1.09e-14 67.0 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,27E8I@186827|Aerococcaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 gnl|extdb|FAM24227-i1-1.1_000458 1121871.AUAT01000005_gene1767 1.35e-50 163.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,27E4B@186827|Aerococcaceae 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P gnl|extdb|FAM24227-i1-1.1_000459 883112.HMPREF9707_00889 6.45e-126 366.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,27DGY@186827|Aerococcaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP gnl|extdb|FAM24227-i1-1.1_000460 883112.HMPREF9707_00888 2.23e-98 299.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,27DV8@186827|Aerococcaceae 91061|Bacilli S R3H domain protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H gnl|extdb|FAM24227-i1-1.1_000461 866775.HMPREF9243_0648 6.81e-100 300.0 COG1442@1|root,COG1442@2|Bacteria,1UY8Y@1239|Firmicutes,4HBAE@91061|Bacilli 91061|Bacilli M family 8 gspA - - - - - - - - - - - Glyco_transf_8 gnl|extdb|FAM24227-i1-1.1_000462 1175629.AJTG01000007_gene1017 1.86e-213 602.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HARC@91061|Bacilli,27ECT@186827|Aerococcaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 - - SBP_bac_8 gnl|extdb|FAM24227-i1-1.1_000463 883113.HMPREF9708_00615 3.38e-153 437.0 COG1175@1|root,COG1175@2|Bacteria,1TSIQ@1239|Firmicutes,4HC0D@91061|Bacilli,27EKK@186827|Aerococcaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component - - - ko:K05814 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000464 883113.HMPREF9708_00614 1.83e-157 447.0 COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,4HB8C@91061|Bacilli,27EKD@186827|Aerococcaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000465 1175629.AJTG01000007_gene1020 2.94e-177 504.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HEX9@91061|Bacilli,27EJB@186827|Aerococcaceae 91061|Bacilli P ATPases associated with a variety of cellular activities - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000466 1121871.AUAT01000039_gene1488 2.49e-75 235.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,27DWH@186827|Aerococcaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD gnl|extdb|FAM24227-i1-1.1_000467 1175629.AJTG01000005_gene730 9.51e-40 136.0 COG1725@1|root,COG1725@2|Bacteria,1W6UD@1239|Firmicutes,4I62Y@91061|Bacilli,27EWC@186827|Aerococcaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR gnl|extdb|FAM24227-i1-1.1_000468 1175629.AJTG01000005_gene731 1.27e-105 311.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HC2V@91061|Bacilli,27EMT@186827|Aerococcaceae 91061|Bacilli V ATPases associated with a variety of cellular activities yhcG - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000469 1175629.AJTG01000005_gene732 3.94e-59 196.0 29MRT@1|root,308PM@2|Bacteria,1U3SK@1239|Firmicutes,4IDJH@91061|Bacilli,27EY9@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000471 1121871.AUAT01000005_gene1764 2.49e-279 773.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,27DGU@186827|Aerococcaceae 91061|Bacilli G PTS system trehalose-specific IIBC component treP - 2.7.1.201 ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_000472 592010.GCWU000182_001972 2.53e-305 843.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,27DGR@186827|Aerococcaceae 91061|Bacilli G Alpha-amylase domain treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C gnl|extdb|FAM24227-i1-1.1_000473 1408438.JADD01000005_gene1182 2.13e-77 236.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HGH2@91061|Bacilli,27E2Q@186827|Aerococcaceae 91061|Bacilli S Bacterial transferase hexapeptide repeat protein - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac gnl|extdb|FAM24227-i1-1.1_000474 1033734.CAET01000038_gene247 4.43e-72 223.0 COG0431@1|root,COG0431@2|Bacteria,1TP8I@1239|Firmicutes,4HACX@91061|Bacilli,1ZCIR@1386|Bacillus 91061|Bacilli S NAD(P)H-dependent FMN reductase - - - - - - - - - - - - FMN_red gnl|extdb|FAM24227-i1-1.1_000475 883112.HMPREF9707_00881 1.63e-77 254.0 COG5401@1|root,COG5401@2|Bacteria,1U8MV@1239|Firmicutes,4HS53@91061|Bacilli,27ET6@186827|Aerococcaceae 91061|Bacilli S Sporulation and spore germination - - - - - - - - - - - - Germane gnl|extdb|FAM24227-i1-1.1_000476 211114.JOEF01000034_gene1388 1.02e-22 94.4 COG5500@1|root,COG5500@2|Bacteria,2INAA@201174|Actinobacteria,4E6RG@85010|Pseudonocardiales 201174|Actinobacteria S Domain of unknown function (DUF1772) - - - - - - - - - - - - DUF1772 gnl|extdb|FAM24227-i1-1.1_000477 1121871.AUAT01000005_gene1759 3.14e-68 229.0 COG2367@1|root,COG2367@2|Bacteria,1V9PM@1239|Firmicutes,4I6BS@91061|Bacilli,27E0P@186827|Aerococcaceae 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 gnl|extdb|FAM24227-i1-1.1_000478 1175629.AJTG01000031_gene1564 3.11e-88 268.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,27DXC@186827|Aerococcaceae 91061|Bacilli K UTRA treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA gnl|extdb|FAM24227-i1-1.1_000479 883112.HMPREF9707_00877 1.39e-236 661.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,27DIV@186827|Aerococcaceae 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N gnl|extdb|FAM24227-i1-1.1_000480 1408438.JADD01000027_gene909 1.65e-89 265.0 COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,4IQBS@91061|Bacilli,27E52@186827|Aerococcaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX gnl|extdb|FAM24227-i1-1.1_000481 883112.HMPREF9707_00875 0.0 985.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,27DGW@186827|Aerococcaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc gnl|extdb|FAM24227-i1-1.1_000482 208596.CAR_c10640 1e-42 149.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,27GDR@186828|Carnobacteriaceae 91061|Bacilli U Signal peptidase, peptidase S26 sipS - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 gnl|extdb|FAM24227-i1-1.1_000483 936140.AEOT01000027_gene1217 9.51e-68 221.0 COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,4HC5J@91061|Bacilli,3F4VM@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LysR family cpsY - - - - - - - - - - - HTH_1,LysR_substrate gnl|extdb|FAM24227-i1-1.1_000484 935845.JADQ01000022_gene4065 9.51e-259 729.0 COG0747@1|root,COG4166@1|root,COG0747@2|Bacteria,COG4166@2|Bacteria,1UEWY@1239|Firmicutes,4HB30@91061|Bacilli,26VPD@186822|Paenibacillaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_000487 1384057.CD33_01525 6.94e-225 641.0 COG1123@1|root,COG4172@2|Bacteria,1UZK8@1239|Firmicutes,4HTUD@91061|Bacilli,3IWIB@400634|Lysinibacillus 91061|Bacilli P Belongs to the ABC transporter superfamily oppF - - ko:K02031,ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_000488 1123251.ATWM01000001_gene487 3.51e-43 149.0 2BM9Y@1|root,32FTT@2|Bacteria,2H0IP@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000489 1175629.AJTG01000022_gene1756 3.07e-85 259.0 COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,27EQD@186827|Aerococcaceae 91061|Bacilli L DNA alkylation repair enzyme alkD - - - - - - - - - - - DNA_alkylation gnl|extdb|FAM24227-i1-1.1_000490 1121024.AUCD01000039_gene174 1.22e-120 350.0 COG0451@1|root,COG0451@2|Bacteria,1V0AK@1239|Firmicutes,4HE2G@91061|Bacilli,27FVI@186828|Carnobacteriaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - Epimerase gnl|extdb|FAM24227-i1-1.1_000491 180332.JTGN01000005_gene3081 3.8e-72 229.0 COG3231@1|root,COG3231@2|Bacteria,1V0NN@1239|Firmicutes,24CPV@186801|Clostridia 186801|Clostridia J Phosphotransferase enzyme family - - 2.7.1.95 ko:K00897,ko:K19299 - - - - br01600,ko00000,ko01000,ko01504 - - - APH gnl|extdb|FAM24227-i1-1.1_000493 1209989.TepiRe1_0994 1.12e-35 133.0 COG3279@1|root,COG3279@2|Bacteria,1VBY3@1239|Firmicutes,24GY2@186801|Clostridia 186801|Clostridia KT LytTr DNA-binding domain protein - - - - - - - - - - - - LytTR,Response_reg gnl|extdb|FAM24227-i1-1.1_000494 610130.Closa_2480 2.54e-46 172.0 COG3290@1|root,COG3290@2|Bacteria,1V83K@1239|Firmicutes,25B4P@186801|Clostridia,2246R@1506553|Lachnoclostridium 186801|Clostridia T GHKL domain - - - - - - - - - - - - HATPase_c_5 gnl|extdb|FAM24227-i1-1.1_000495 515620.EUBELI_20088 0.000277 48.1 COG4512@1|root,COG4512@2|Bacteria,1VKH5@1239|Firmicutes,24QIQ@186801|Clostridia,25XP5@186806|Eubacteriaceae 186801|Clostridia KOT CytoplasmicMembrane, score - - - ko:K07813 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01002 - - - AgrB gnl|extdb|FAM24227-i1-1.1_000500 180332.JTGN01000014_gene726 1.57e-08 62.8 2DPV9@1|root,333IN@2|Bacteria,1VEQ0@1239|Firmicutes,25DXE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000501 246199.CUS_4536 1.2e-69 218.0 COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,3WIM2@541000|Ruminococcaceae 186801|Clostridia V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000502 1408438.JADD01000002_gene343 2.72e-116 350.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,27DH3@186827|Aerococcaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yfkN - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - iYO844.BSU07840 5_nucleotid_C,Metallophos gnl|extdb|FAM24227-i1-1.1_000503 1408438.JADD01000002_gene344 9.57e-121 352.0 COG3639@1|root,COG3639@2|Bacteria,1V15B@1239|Firmicutes,4IQWU@91061|Bacilli,27EA4@186827|Aerococcaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000504 1408438.JADD01000002_gene345 1.38e-136 392.0 COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,27EBE@186827|Aerococcaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000505 883110.HMPREF9260_01446 6.1e-145 414.0 COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,27DHH@186827|Aerococcaceae 91061|Bacilli P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000506 1408438.JADD01000002_gene347 3.15e-151 432.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,27EF1@186827|Aerococcaceae 91061|Bacilli P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd gnl|extdb|FAM24227-i1-1.1_000507 1121024.AUCD01000003_gene1359 1.09e-101 302.0 COG1082@1|root,COG1082@2|Bacteria,1VHIG@1239|Firmicutes,4HPT7@91061|Bacilli,27HBN@186828|Carnobacteriaceae 91061|Bacilli G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 gnl|extdb|FAM24227-i1-1.1_000508 1120954.ATXE01000001_gene1666 1.1e-12 68.9 COG0673@1|root,COG0673@2|Bacteria,2GM7J@201174|Actinobacteria 201174|Actinobacteria K oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C gnl|extdb|FAM24227-i1-1.1_000509 525255.HMPREF0077_1801 1.41e-09 58.5 COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,22I58@1570339|Peptoniphilaceae 186801|Clostridia S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C gnl|extdb|FAM24227-i1-1.1_000510 1122128.AUEE01000023_gene1390 1.17e-27 112.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,4GY8U@90964|Staphylococcaceae 91061|Bacilli S ABC transporter yheS_2 - - ko:K18231 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn gnl|extdb|FAM24227-i1-1.1_000511 1120998.AUFC01000027_gene2493 6.45e-78 244.0 COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WCMY@538999|Clostridiales incertae sedis 186801|Clostridia S Calcineurin-like phosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos gnl|extdb|FAM24227-i1-1.1_000512 565655.ECBG_00596 2.12e-68 215.0 COG1418@1|root,COG1418@2|Bacteria,1VF80@1239|Firmicutes,4IC89@91061|Bacilli,4B51R@81852|Enterococcaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06950 - - - - ko00000 - - - HD gnl|extdb|FAM24227-i1-1.1_000513 1123308.KB904559_gene1379 5.12e-49 171.0 COG0454@1|root,COG0456@2|Bacteria,1VD7Z@1239|Firmicutes,4HGYD@91061|Bacilli 91061|Bacilli K Acetyltransferase GNAT family XK27_00115 - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 gnl|extdb|FAM24227-i1-1.1_000514 1408321.JNJD01000009_gene1697 1.3e-37 134.0 COG1051@1|root,COG1051@2|Bacteria,1VFCJ@1239|Firmicutes,25GX2@186801|Clostridia 186801|Clostridia F NUDIX domain - - - - - - - - - - - - NUDIX gnl|extdb|FAM24227-i1-1.1_000518 1408438.JADD01000006_gene1015 3.45e-46 165.0 COG3290@1|root,COG3290@2|Bacteria,1UW0Z@1239|Firmicutes,4I3H0@91061|Bacilli,27EQF@186827|Aerococcaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c_5 gnl|extdb|FAM24227-i1-1.1_000519 1201292.DR75_1828 2.14e-16 77.8 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,4B153@81852|Enterococcaceae 91061|Bacilli K LytTr DNA-binding domain agrA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg gnl|extdb|FAM24227-i1-1.1_000447 1121871.AUAT01000005_gene1777 1.96e-49 165.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,27DXU@186827|Aerococcaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB gnl|extdb|FAM24227-i1-1.1_000485 1007103.AFHW01000185_gene744 8.72e-142 423.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,26Q9W@186822|Paenibacillaceae 91061|Bacilli EP ABC transporter permease - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N gnl|extdb|FAM24227-i1-1.1_000486 1246626.BleG1_0609 1.84e-154 452.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,1ZEM2@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000520 1121105.ATXL01000017_gene1609 8.23e-153 431.0 COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,4HCFH@91061|Bacilli 91061|Bacilli L COG1484 DNA replication protein - - - - - - - - - - - - IstB_IS21,IstB_IS21_ATP gnl|extdb|FAM24227-i1-1.1_000521 866775.HMPREF9243_0755 5.49e-23 93.6 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - ThrE_2 gnl|extdb|FAM24227-i1-1.1_000522 1158606.I579_00014 6.83e-06 47.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,4B34X@81852|Enterococcaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 gnl|extdb|FAM24227-i1-1.1_000523 883112.HMPREF9707_00256 3.15e-05 45.8 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,27DU2@186827|Aerococcaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE gnl|extdb|FAM24227-i1-1.1_000524 1118057.CAGX01000018_gene1425 3.61e-07 51.6 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,22G98@1570339|Peptoniphilaceae 186801|Clostridia S cog cog2966 - - - - - - - - - - - - ThrE gnl|extdb|FAM24227-i1-1.1_000525 1139219.I569_00768 2.56e-41 145.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,4B16U@81852|Enterococcaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE gnl|extdb|FAM24227-i1-1.1_000526 1121871.AUAT01000012_gene597 5.99e-06 51.6 2DD5C@1|root,2ZGKK@2|Bacteria,1W4I9@1239|Firmicutes,4I0G3@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000527 1158607.UAU_02577 3.5e-189 534.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,4AZ72@81852|Enterococcaceae 91061|Bacilli E TOBE domain msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 gnl|extdb|FAM24227-i1-1.1_000528 1121105.ATXL01000007_gene1083 1.45e-103 307.0 COG1737@1|root,COG1737@2|Bacteria,1V5JY@1239|Firmicutes,4HI0D@91061|Bacilli,4B0V7@81852|Enterococcaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family yecA - - - - - - - - - - - HTH_6,SIS gnl|extdb|FAM24227-i1-1.1_000530 1158610.UC3_03504 8.02e-13 72.0 COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,4IRFB@91061|Bacilli,4B2XM@81852|Enterococcaceae 91061|Bacilli S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 gnl|extdb|FAM24227-i1-1.1_000531 565653.EGBG_01412 1.38e-284 790.0 COG1653@1|root,COG1653@2|Bacteria,1TQ1D@1239|Firmicutes,4HC43@91061|Bacilli,4AZS1@81852|Enterococcaceae 91061|Bacilli G ABC transporter substrate-binding protein - - - ko:K17318 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - SBP_bac_8 gnl|extdb|FAM24227-i1-1.1_000534 1158610.UC3_03503 2.99e-124 365.0 COG1940@1|root,COG1940@2|Bacteria,1V20R@1239|Firmicutes,4HFXJ@91061|Bacilli,4B1QJ@81852|Enterococcaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK gnl|extdb|FAM24227-i1-1.1_000535 565653.EGBG_01408 1e-136 398.0 COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,4B1JT@81852|Enterococcaceae 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 gnl|extdb|FAM24227-i1-1.1_000536 1139219.I569_02396 3.09e-261 744.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,4AZJE@81852|Enterococcaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family bglX - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C gnl|extdb|FAM24227-i1-1.1_000537 1158610.UC3_03510 8.69e-280 772.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,4AZGA@81852|Enterococcaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 gnl|extdb|FAM24227-i1-1.1_000538 1462526.BN990_00449 5.63e-60 211.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,4C6HR@84406|Virgibacillus 91061|Bacilli G FGGY family of carbohydrate kinases, C-terminal domain gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N gnl|extdb|FAM24227-i1-1.1_000539 35841.BT1A1_0295 1e-82 258.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,1ZS1B@1386|Bacillus 91061|Bacilli G 6-phosphogluconate dehydrogenase yqeC - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 gnl|extdb|FAM24227-i1-1.1_000540 1122143.AUEG01000018_gene1876 1.23e-258 716.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli,27GZ0@186828|Carnobacteriaceae 91061|Bacilli G Family 4 glycosyl hydrolase - - 3.2.1.122 ko:K01232 ko00500,map00500 - R00837,R00838,R06113 RC00049 ko00000,ko00001,ko01000 - GH4 - Glyco_hydro_4,Glyco_hydro_4C gnl|extdb|FAM24227-i1-1.1_000543 1232446.BAIE02000012_gene1568 6.1e-11 64.7 COG1737@1|root,COG1737@2|Bacteria,1V5WH@1239|Firmicutes,25CED@186801|Clostridia 186801|Clostridia K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS gnl|extdb|FAM24227-i1-1.1_000546 1158607.UAU_00797 9.38e-310 862.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,4B0MR@81852|Enterococcaceae 91061|Bacilli P E1-E2 ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase gnl|extdb|FAM24227-i1-1.1_000547 1449337.JQLL01000001_gene1450 1.43e-148 424.0 COG1176@1|root,COG1176@2|Bacteria,1TRUC@1239|Firmicutes,4HABA@91061|Bacilli,27HZQ@186828|Carnobacteriaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component cysT7 - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000548 1449337.JQLL01000001_gene1449 1.46e-131 379.0 COG1177@1|root,COG1177@2|Bacteria,1TR8H@1239|Firmicutes,4HCRJ@91061|Bacilli 91061|Bacilli P Spermidine Putrescine potC3 - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000549 1449337.JQLL01000001_gene1448 5.5e-177 502.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA11 - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 gnl|extdb|FAM24227-i1-1.1_000550 1449337.JQLL01000001_gene1447 1.24e-184 521.0 COG0687@1|root,COG0687@2|Bacteria,1TRE1@1239|Firmicutes,4HDMV@91061|Bacilli 91061|Bacilli E Spermidine putrescine ABC transporter, substratebinding protein potD3 - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6,SBP_bac_8 gnl|extdb|FAM24227-i1-1.1_000552 1449337.JQLL01000001_gene1445 6.71e-205 580.0 COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HBV3@91061|Bacilli 91061|Bacilli F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - - - - - - - - - - Amidohydro_1 gnl|extdb|FAM24227-i1-1.1_000553 1266845.Q783_10030 9.06e-62 192.0 COG1959@1|root,COG1959@2|Bacteria,1VBCR@1239|Firmicutes,4HMBH@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - Rrf2 gnl|extdb|FAM24227-i1-1.1_000554 1266845.Q783_10025 3.38e-145 417.0 COG0492@1|root,COG0492@2|Bacteria,1TSQS@1239|Firmicutes,4HC5G@91061|Bacilli 91061|Bacilli O Pyridine nucleotide-disulfide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 gnl|extdb|FAM24227-i1-1.1_000555 1266845.Q783_10020 6.88e-58 187.0 COG0500@1|root,COG0500@2|Bacteria,1UHQ8@1239|Firmicutes,4IS63@91061|Bacilli 91061|Bacilli Q O-methyltransferase - - - - - - - - - - - - Methyltransf_23,Methyltransf_31 gnl|extdb|FAM24227-i1-1.1_000557 866775.HMPREF9243_0814 1.15e-61 204.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,27DZG@186827|Aerococcaceae 91061|Bacilli M Transporter, small conductance mechanosensitive ion channel MscS family protein ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel gnl|extdb|FAM24227-i1-1.1_000558 1121024.AUCD01000024_gene750 9.38e-84 254.0 COG2364@1|root,COG2364@2|Bacteria,1TU2A@1239|Firmicutes,4I6M6@91061|Bacilli,27GXT@186828|Carnobacteriaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000559 945021.TEH_21640 2.19e-46 155.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,4B2B5@81852|Enterococcaceae 91061|Bacilli T Universal stress protein family uspA - - - - - - - - - - - Usp gnl|extdb|FAM24227-i1-1.1_000560 1121871.AUAT01000037_gene1340 8.88e-16 81.3 2C30J@1|root,332HD@2|Bacteria,1VGUU@1239|Firmicutes,4HQAZ@91061|Bacilli,27E6K@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000561 592010.GCWU000182_000402 1.24e-218 619.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4ISAE@91061|Bacilli,27DCU@186827|Aerococcaceae 91061|Bacilli C Fumarate reductase flavoprotein subunit frdC - 1.3.5.1,1.3.5.4 ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C gnl|extdb|FAM24227-i1-1.1_000562 696281.Desru_3029 1e-54 196.0 COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,24BZZ@186801|Clostridia 186801|Clostridia S Membrane - - - - - - - - - - - - bPH_5 gnl|extdb|FAM24227-i1-1.1_000563 1139996.OMQ_00551 6.66e-29 108.0 COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,4HMKR@91061|Bacilli,4B3IN@81852|Enterococcaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR gnl|extdb|FAM24227-i1-1.1_000564 1449342.JQMR01000001_gene1460 7.36e-80 247.0 COG0730@1|root,COG0730@2|Bacteria,1V46C@1239|Firmicutes,4HGYI@91061|Bacilli 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE gnl|extdb|FAM24227-i1-1.1_000565 1123359.AUIQ01000018_gene249 0.0 867.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,4AZGA@81852|Enterococcaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 gnl|extdb|FAM24227-i1-1.1_000566 208596.CAR_c09130 1.3e-88 268.0 COG2188@1|root,COG2188@2|Bacteria,1V2M8@1239|Firmicutes,4HGRM@91061|Bacilli 91061|Bacilli K Transcriptional regulator yydK - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA gnl|extdb|FAM24227-i1-1.1_000567 883112.HMPREF9707_00070 2.3e-111 327.0 COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,27DU0@186827|Aerococcaceae 91061|Bacilli P ABC transporter, permease protein metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000568 883112.HMPREF9707_00069 2e-174 495.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,27DSS@186827|Aerococcaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL gnl|extdb|FAM24227-i1-1.1_000569 883113.HMPREF9708_00582 1.78e-166 478.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,27DMP@186827|Aerococcaceae 91061|Bacilli E Aminotransferase class I and II aspC - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_000570 742733.HMPREF9469_00746 2.09e-147 433.0 COG2851@1|root,COG2851@2|Bacteria,1TQQH@1239|Firmicutes,24A61@186801|Clostridia,21Z2B@1506553|Lachnoclostridium 186801|Clostridia C Citrate transporter - - - - - - - - - - - - CitMHS gnl|extdb|FAM24227-i1-1.1_000571 873448.STRPO_1134 1.88e-49 165.0 COG3697@1|root,COG3697@2|Bacteria,1VGT9@1239|Firmicutes,4IRQX@91061|Bacilli 91061|Bacilli HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citX - 2.7.7.61 ko:K05964 ko02020,map02020 - R10706 - ko00000,ko00001,ko01000 - - - CitX gnl|extdb|FAM24227-i1-1.1_000572 663952.SDD27957_04995 6.04e-287 793.0 COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,4HAE1@91061|Bacilli,1M91A@119603|Streptococcus dysgalactiae group 91061|Bacilli H Citrate lyase, alpha subunit citF - 2.8.3.10 ko:K01643 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - CitF gnl|extdb|FAM24227-i1-1.1_000573 873447.SPB_1340 8.57e-158 448.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli 91061|Bacilli G Belongs to the HpcH HpaI aldolase family citE - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI,PK gnl|extdb|FAM24227-i1-1.1_000574 1158607.UAU_00477 1.78e-40 136.0 COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,4HKPN@91061|Bacilli,4B3JQ@81852|Enterococcaceae 91061|Bacilli C Covalent carrier of the coenzyme of citrate lyase citD - - ko:K01646 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001 - - - ACP gnl|extdb|FAM24227-i1-1.1_000575 565653.EGBG_00285 2.49e-127 374.0 COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,4HC6Q@91061|Bacilli,4B0CY@81852|Enterococcaceae 91061|Bacilli H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase citC - 6.2.1.22 ko:K01910 ko02020,map02020 - R04449 RC00012,RC00039 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_10,Citrate_ly_lig gnl|extdb|FAM24227-i1-1.1_000576 1121024.AUCD01000054_gene1110 3.83e-237 669.0 COG4770@1|root,COG5016@1|root,COG4770@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,4HBJ1@91061|Bacilli,27G3E@186828|Carnobacteriaceae 91061|Bacilli C HMGL-like oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA gnl|extdb|FAM24227-i1-1.1_000577 1158607.UAU_02992 2.49e-06 49.3 28RE2@1|root,2ZDTB@2|Bacteria,1W2XT@1239|Firmicutes,4I1IK@91061|Bacilli 91061|Bacilli S Oxaloacetate decarboxylase, gamma chain - - - - - - - - - - - - OAD_gamma gnl|extdb|FAM24227-i1-1.1_000578 759913.SDSE_1026 5.94e-20 85.5 COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,4HQ6S@91061|Bacilli,1MA34@119603|Streptococcus dysgalactiae group 91061|Bacilli I Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl gnl|extdb|FAM24227-i1-1.1_000579 945021.TEH_07880 1.18e-186 528.0 COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,4HEF4@91061|Bacilli,4B0CM@81852|Enterococcaceae 91061|Bacilli C Na+-transporting oxaloacetate decarboxylase beta subunit gcdB - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta gnl|extdb|FAM24227-i1-1.1_000580 1123359.AUIQ01000086_gene128 5.28e-99 295.0 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HATG@91061|Bacilli,4B01Y@81852|Enterococcaceae 91061|Bacilli K FCD domain citR - - - - - - - - - - - FCD,GntR gnl|extdb|FAM24227-i1-1.1_000582 883113.HMPREF9708_00412 4.6e-67 209.0 COG4720@1|root,COG4720@2|Bacteria,1V5I7@1239|Firmicutes,4HK9Q@91061|Bacilli,27E3D@186827|Aerococcaceae 91061|Bacilli S Pfam:DUF3816 - - - - - - - - - - - - ECF_trnsprt gnl|extdb|FAM24227-i1-1.1_000583 1408438.JADD01000006_gene998 2.3e-158 456.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli,27DVT@186827|Aerococcaceae 91061|Bacilli E FAD dependent oxidoreductase yurR - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO gnl|extdb|FAM24227-i1-1.1_000584 883110.HMPREF9260_01748 2.28e-58 183.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,27E7Q@186827|Aerococcaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL gnl|extdb|FAM24227-i1-1.1_000585 585501.HMPREF6123_2017 2.92e-68 223.0 COG1476@1|root,COG1476@2|Bacteria,1V36C@1239|Firmicutes,24933@186801|Clostridia,2PRYQ@265975|Oribacterium 186801|Clostridia K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 gnl|extdb|FAM24227-i1-1.1_000587 1408438.JADD01000006_gene995 1.05e-63 211.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli,27E8R@186827|Aerococcaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 gnl|extdb|FAM24227-i1-1.1_000589 883110.HMPREF9260_01744 2.16e-35 124.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli 91061|Bacilli L endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG gnl|extdb|FAM24227-i1-1.1_000590 883112.HMPREF9707_01048 5.73e-100 298.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,27DUJ@186827|Aerococcaceae 91061|Bacilli S Methyltransferase small domain protein yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS gnl|extdb|FAM24227-i1-1.1_000591 1408438.JADD01000006_gene991 2.34e-29 109.0 COG4467@1|root,COG4467@2|Bacteria,1VHN5@1239|Firmicutes,4HPNB@91061|Bacilli,27E7S@186827|Aerococcaceae 91061|Bacilli S Initiation control protein YabA - - - - - - - - - - - - YabB gnl|extdb|FAM24227-i1-1.1_000592 883112.HMPREF9707_01046 1.11e-75 242.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,27DZC@186827|Aerococcaceae 91061|Bacilli L DNA polymerase III, delta' subunit holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C gnl|extdb|FAM24227-i1-1.1_000593 1121871.AUAT01000005_gene1716 1.26e-48 157.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,27E2M@186827|Aerococcaceae 91061|Bacilli S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec gnl|extdb|FAM24227-i1-1.1_000594 883112.HMPREF9707_01044 1.21e-97 289.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,27DWA@186827|Aerococcaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin gnl|extdb|FAM24227-i1-1.1_000595 1408438.JADD01000006_gene987 7.16e-125 357.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,27DE8@186827|Aerococcaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 gnl|extdb|FAM24227-i1-1.1_000597 866775.HMPREF9243_0737 1.87e-52 172.0 COG4720@1|root,COG4720@2|Bacteria,1VC0F@1239|Firmicutes,4HMJM@91061|Bacilli,27E3P@186827|Aerococcaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS gnl|extdb|FAM24227-i1-1.1_000598 1408438.JADD01000006_gene985 2.64e-221 640.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,27DK0@186827|Aerococcaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 gnl|extdb|FAM24227-i1-1.1_000599 1408438.JADD01000006_gene983 1.78e-275 774.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,27DNN@186827|Aerococcaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N gnl|extdb|FAM24227-i1-1.1_000601 1408438.JADD01000017_gene1412 0.0 1114.0 COG0431@1|root,COG1053@1|root,COG3976@1|root,COG0431@2|Bacteria,COG1053@2|Bacteria,COG3976@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,27EAP@186827|Aerococcaceae 91061|Bacilli C hmm pf01266 - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FMN_bind,FMN_red,Shikimate_dh_N gnl|extdb|FAM24227-i1-1.1_000602 565653.EGBG_00908 1.55e-90 270.0 COG0431@1|root,COG0431@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli,4B6CH@81852|Enterococcaceae 91061|Bacilli S NADPH-dependent FMN reductase - - 1.5.1.36 ko:K19784,ko:K22394 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red,PAS_10 gnl|extdb|FAM24227-i1-1.1_000603 1158614.I592_00522 3.26e-96 293.0 COG0583@1|root,COG0583@2|Bacteria,1TTAM@1239|Firmicutes,4HFT5@91061|Bacilli,4B1MC@81852|Enterococcaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate gnl|extdb|FAM24227-i1-1.1_000604 208596.CAR_c23230 5.19e-08 55.1 28H7K@1|root,2Z7JT@2|Bacteria,1UPH1@1239|Firmicutes,4HE88@91061|Bacilli,27GVB@186828|Carnobacteriaceae 91061|Bacilli P 2-keto-3-deoxygluconate permease - - - ko:K02526 - - - - ko00000,ko02000 2.A.10.1 - - KdgT gnl|extdb|FAM24227-i1-1.1_000606 208596.CAR_c23230 9.24e-07 51.2 28H7K@1|root,2Z7JT@2|Bacteria,1UPH1@1239|Firmicutes,4HE88@91061|Bacilli,27GVB@186828|Carnobacteriaceae 91061|Bacilli P 2-keto-3-deoxygluconate permease - - - ko:K02526 - - - - ko00000,ko02000 2.A.10.1 - - KdgT gnl|extdb|FAM24227-i1-1.1_000529 565653.EGBG_01414 9.9e-191 543.0 COG5520@1|root,COG5520@2|Bacteria,1URVQ@1239|Firmicutes,4HE4Z@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 30 family - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - Glyco_hydro_30,Glyco_hydro_30C gnl|extdb|FAM24227-i1-1.1_000532 565653.EGBG_01411 2.28e-177 498.0 COG0395@1|root,COG0395@2|Bacteria,1TSKG@1239|Firmicutes,4HCDM@91061|Bacilli,4B0PE@81852|Enterococcaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K17320 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000533 565653.EGBG_01410 4.88e-181 508.0 COG4209@1|root,COG4209@2|Bacteria,1TQ64@1239|Firmicutes,4HD1Z@91061|Bacilli,4AZ8H@81852|Enterococcaceae 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - - - ko:K17319 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000541 208596.CAR_c19350 5.61e-259 724.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,27FSN@186828|Carnobacteriaceae 91061|Bacilli G phosphotransferase system, EIIB - - 2.7.1.199,2.7.1.208 ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266 R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3 - - PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_000542 457396.CSBG_02237 4.16e-24 99.8 COG1737@1|root,COG1737@2|Bacteria,1TR75@1239|Firmicutes,24DF8@186801|Clostridia,36GCP@31979|Clostridiaceae 186801|Clostridia K Transcriptional regulator - - - - - - - - - - - - HTH_6,SIS gnl|extdb|FAM24227-i1-1.1_000551 1449337.JQLL01000001_gene1446 2.23e-274 766.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli 91061|Bacilli F adenine deaminase yerA GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 gnl|extdb|FAM24227-i1-1.1_000581 1158610.UC3_02272 2.7e-87 268.0 COG1767@1|root,COG1767@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,4B163@81852|Enterococcaceae 91061|Bacilli H ATP:dephospho-CoA triphosphoribosyl transferase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG gnl|extdb|FAM24227-i1-1.1_000586 592010.GCWU000182_000870 6.93e-82 247.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,27E2X@186827|Aerococcaceae 91061|Bacilli L Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco gnl|extdb|FAM24227-i1-1.1_000588 908337.HMPREF9257_0718 1.7e-110 328.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,27DSC@186827|Aerococcaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase gnl|extdb|FAM24227-i1-1.1_000596 1121871.AUAT01000005_gene1719 3.99e-38 130.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,27E4F@186827|Aerococcaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd gnl|extdb|FAM24227-i1-1.1_000544 1449343.JQLQ01000002_gene2401 4.51e-12 67.8 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,27FJ8@186828|Carnobacteriaceae 91061|Bacilli P E1-E2 ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase gnl|extdb|FAM24227-i1-1.1_000607 883113.HMPREF9708_01302 3.37e-292 813.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27DH5@186827|Aerococcaceae 91061|Bacilli V ABC transporter transmembrane region mdlB - - ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_000608 883112.HMPREF9707_00733 1.69e-284 793.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27DH0@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein mdlA - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_000610 1121871.AUAT01000015_gene229 3.49e-33 115.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HNN9@91061|Bacilli,27E4K@186827|Aerococcaceae 91061|Bacilli S Uncharacterised protein family (UPF0154) yneF - - ko:K09976 - - - - ko00000 - - - UPF0154 gnl|extdb|FAM24227-i1-1.1_000611 1408438.JADD01000022_gene52 1.43e-26 99.8 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,27E5W@186827|Aerococcaceae 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 gnl|extdb|FAM24227-i1-1.1_000612 1121871.AUAT01000015_gene227 2.44e-108 316.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,27DP2@186827|Aerococcaceae 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 gnl|extdb|FAM24227-i1-1.1_000613 883112.HMPREF9707_00737 1.87e-95 280.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,27DUY@186827|Aerococcaceae 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran gnl|extdb|FAM24227-i1-1.1_000614 908337.HMPREF9257_1001 3.68e-266 762.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,27DSR@186827|Aerococcaceae 91061|Bacilli L Single-strand DNA-specific exonuclease, C terminal domain recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C gnl|extdb|FAM24227-i1-1.1_000615 1408438.JADD01000022_gene45 9.82e-09 57.8 COG5416@1|root,COG5416@2|Bacteria,1VHTF@1239|Firmicutes,4I628@91061|Bacilli,27E6P@186827|Aerococcaceae 91061|Bacilli S Pfam:DUF1049 - - - - - - - - - - - - LapA_dom gnl|extdb|FAM24227-i1-1.1_000616 945021.TEH_13380 8.78e-68 218.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,4B0P4@81852|Enterococcaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short gnl|extdb|FAM24227-i1-1.1_000617 1408438.JADD01000022_gene44 6.37e-148 424.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,27DH9@186827|Aerococcaceae 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 gnl|extdb|FAM24227-i1-1.1_000618 883112.HMPREF9707_00740 4.37e-264 744.0 COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,27DHT@186827|Aerococcaceae 91061|Bacilli I Acyltransferase family oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 gnl|extdb|FAM24227-i1-1.1_000619 592010.GCWU000182_001365 2.38e-225 631.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,27DRM@186827|Aerococcaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 gnl|extdb|FAM24227-i1-1.1_000620 1121871.AUAT01000015_gene219 7.79e-248 708.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,27DJ0@186827|Aerococcaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f gnl|extdb|FAM24227-i1-1.1_000621 1121871.AUAT01000015_gene218 1.13e-187 524.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,27DKD@186827|Aerococcaceae 91061|Bacilli J glycyl-tRNA synthetase, alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e gnl|extdb|FAM24227-i1-1.1_000622 908337.HMPREF9257_1009 3.65e-90 275.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,27DYX@186827|Aerococcaceae 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N gnl|extdb|FAM24227-i1-1.1_000623 1408438.JADD01000004_gene1110 1.54e-170 481.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,27DPY@186827|Aerococcaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 gnl|extdb|FAM24227-i1-1.1_000624 1280696.ATVY01000003_gene347 1.21e-29 110.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia,4BZCW@830|Butyrivibrio 186801|Clostridia M Prokaryotic diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar,PAP2 gnl|extdb|FAM24227-i1-1.1_000625 908337.HMPREF9257_1012 2.17e-55 178.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,27E4J@186827|Aerococcaceae 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 gnl|extdb|FAM24227-i1-1.1_000626 883113.HMPREF9708_01286 4.87e-194 575.0 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,27ED4@186827|Aerococcaceae 91061|Bacilli S 7TM-HD extracellular yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD gnl|extdb|FAM24227-i1-1.1_000627 883113.HMPREF9708_01285 1.25e-179 506.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,27DQX@186827|Aerococcaceae 91061|Bacilli T PhoH-like protein phoH - - ko:K06217 - - - - ko00000 - - - PhoH gnl|extdb|FAM24227-i1-1.1_000628 883113.HMPREF9708_01497 3.81e-302 842.0 COG1409@1|root,COG1409@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli 91061|Bacilli DZ Purple acid Phosphatase, N-terminal domain ppe1 - - - - - - - - - - - Metallophos,Pur_ac_phosph_N,SLH,fn3 gnl|extdb|FAM24227-i1-1.1_000629 592010.GCWU000182_001393 3.39e-57 182.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,27E1A@186827|Aerococcaceae 91061|Bacilli S Yqey-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY gnl|extdb|FAM24227-i1-1.1_000630 1121871.AUAT01000015_gene212 4.21e-26 96.7 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,27E58@186827|Aerococcaceae 91061|Bacilli J Ribosomal protein S21 rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 gnl|extdb|FAM24227-i1-1.1_000631 592010.GCWU000182_001389 2.17e-52 171.0 COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,27E1E@186827|Aerococcaceae 91061|Bacilli P Belongs to the Fur family zur - - ko:K02076,ko:K03711 - - - - ko00000,ko03000 - - - FUR gnl|extdb|FAM24227-i1-1.1_000632 1408438.JADD01000004_gene1140 2.23e-133 385.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,27DE0@186827|Aerococcaceae 91061|Bacilli S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase gnl|extdb|FAM24227-i1-1.1_000633 883112.HMPREF9707_00751 1.8e-161 458.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 gnl|extdb|FAM24227-i1-1.1_000634 908337.HMPREF9257_1017 0.0 931.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,27DD7@186827|Aerococcaceae 91061|Bacilli J L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon gnl|extdb|FAM24227-i1-1.1_000635 1408438.JADD01000003_gene184 4.89e-217 610.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,27DEE@186827|Aerococcaceae 91061|Bacilli J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His gnl|extdb|FAM24227-i1-1.1_000636 1408438.JADD01000003_gene183 5.24e-133 395.0 COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,27DS0@186827|Aerococcaceae 91061|Bacilli M Ami_3 lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 gnl|extdb|FAM24227-i1-1.1_000639 592010.GCWU000182_000159 9.93e-91 273.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,27DP6@186827|Aerococcaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - iSB619.SA_RS00835 DeoC gnl|extdb|FAM24227-i1-1.1_000640 1408438.JADD01000003_gene179 8.13e-81 249.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,27DZQ@186827|Aerococcaceae 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA gnl|extdb|FAM24227-i1-1.1_000641 592010.GCWU000182_000161 1.23e-112 336.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,27DNI@186827|Aerococcaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA gnl|extdb|FAM24227-i1-1.1_000642 888049.HMPREF8578_1947 1.6e-06 53.1 2E0MY@1|root,32W75@2|Bacteria,1VFZQ@1239|Firmicutes,4HKWR@91061|Bacilli,1WPBE@1303|Streptococcus oralis 91061|Bacilli S Protein of unknown function (DUF3013) XK27_03960 - - - - - - - - - - - DUF3013 gnl|extdb|FAM24227-i1-1.1_000643 883112.HMPREF9707_00765 1.14e-71 216.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,27E04@186827|Aerococcaceae 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA gnl|extdb|FAM24227-i1-1.1_000645 883112.HMPREF9707_00766 2.72e-198 558.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,27DMQ@186827|Aerococcaceae 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 gnl|extdb|FAM24227-i1-1.1_000646 883113.HMPREF9708_01253 6.89e-29 110.0 COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,27E8Z@186827|Aerococcaceae 91061|Bacilli L Reverse transcriptase-like rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H,RVT_3 gnl|extdb|FAM24227-i1-1.1_000647 883113.HMPREF9708_01252 1.01e-40 152.0 2C52V@1|root,32XQT@2|Bacteria,1VDUX@1239|Firmicutes,4HN1I@91061|Bacilli,27E38@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000648 1408438.JADD01000003_gene172 1.97e-48 159.0 2CBH7@1|root,32RTD@2|Bacteria,1VA5J@1239|Firmicutes,4HM3N@91061|Bacilli,27E1R@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2187 gnl|extdb|FAM24227-i1-1.1_000649 1121871.AUAT01000015_gene191 9.85e-105 315.0 COG1597@1|root,COG1597@2|Bacteria,1TQ9A@1239|Firmicutes,4HCPU@91061|Bacilli,27EED@186827|Aerococcaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat gnl|extdb|FAM24227-i1-1.1_000650 1408438.JADD01000019_gene846 2.93e-198 553.0 COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli,27EDD@186827|Aerococcaceae 91061|Bacilli S Rhodanase C-terminal ybfQ - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C gnl|extdb|FAM24227-i1-1.1_000652 883112.HMPREF9707_00771 2.75e-157 450.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,27DDQ@186827|Aerococcaceae 91061|Bacilli K helix_turn _helix lactose operon repressor ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 gnl|extdb|FAM24227-i1-1.1_000653 1121871.AUAT01000015_gene187 6.11e-33 122.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,27E8P@186827|Aerococcaceae 91061|Bacilli S YtxH-like protein ytxH - - - - - - - - - - - YtxH gnl|extdb|FAM24227-i1-1.1_000654 1121871.AUAT01000015_gene186 9.12e-33 123.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,27E22@186827|Aerococcaceae 91061|Bacilli S Bacterial protein of unknown function (DUF948) ytxG - - - - - - - - - - - DUF948 gnl|extdb|FAM24227-i1-1.1_000655 883112.HMPREF9707_00774 3.72e-84 261.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,27DZG@186827|Aerococcaceae 91061|Bacilli M Transporter, small conductance mechanosensitive ion channel MscS family protein ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel gnl|extdb|FAM24227-i1-1.1_000656 1408438.JADD01000004_gene1102 9.75e-62 195.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,27E4C@186827|Aerococcaceae 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 gnl|extdb|FAM24227-i1-1.1_000657 883110.HMPREF9260_00588 7.05e-80 244.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,27DX7@186827|Aerococcaceae 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like gnl|extdb|FAM24227-i1-1.1_000658 908337.HMPREF9257_1047 4.15e-125 364.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,27DPE@186827|Aerococcaceae 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race gnl|extdb|FAM24227-i1-1.1_000659 883112.HMPREF9707_00779 1.1e-139 413.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,27DTJ@186827|Aerococcaceae 91061|Bacilli CP ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 gnl|extdb|FAM24227-i1-1.1_000660 883113.HMPREF9708_01237 3.23e-147 422.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,27DHQ@186827|Aerococcaceae 91061|Bacilli S Domain of unknown function (DUF4162) ysdB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 gnl|extdb|FAM24227-i1-1.1_000661 883112.HMPREF9707_00781 2.44e-251 706.0 2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,4HC1J@91061|Bacilli,27EJH@186827|Aerococcaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score XK27_11280 - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000662 699248.SRA_04746 2.2e-51 177.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli 91061|Bacilli H Belongs to the pyridoxine kinase family pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin gnl|extdb|FAM24227-i1-1.1_000663 1121871.AUAT01000016_gene241 8.07e-54 170.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,27E4T@186827|Aerococcaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin gnl|extdb|FAM24227-i1-1.1_000665 883112.HMPREF9707_00784 1.23e-81 246.0 COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,27E1B@186827|Aerococcaceae 91061|Bacilli S Colicin V production protein cvpA - - - - - - - - - - - Colicin_V gnl|extdb|FAM24227-i1-1.1_000666 592010.GCWU000182_001277 4.16e-25 98.2 COG3027@1|root,COG3027@2|Bacteria,1UW10@1239|Firmicutes,4I4IX@91061|Bacilli,27EYZ@186827|Aerococcaceae 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - - - - - - - - - - ZapA gnl|extdb|FAM24227-i1-1.1_000667 1408438.JADD01000026_gene876 6.82e-118 348.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli,27EIN@186827|Aerococcaceae 91061|Bacilli L Domain of unknown function (DUF3378) rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII gnl|extdb|FAM24227-i1-1.1_000609 1293597.BN147_08735 1.98e-11 63.9 COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,4IEDX@91061|Bacilli,3F6PU@33958|Lactobacillaceae 91061|Bacilli V Abi-like protein - - - - - - - - - - - - Abi_2 gnl|extdb|FAM24227-i1-1.1_000637 883112.HMPREF9707_00758 1.03e-64 201.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,27DZ3@186827|Aerococcaceae 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase gnl|extdb|FAM24227-i1-1.1_000638 883112.HMPREF9707_00759 0.0 1047.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,27DQT@186827|Aerococcaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS gnl|extdb|FAM24227-i1-1.1_000651 883112.HMPREF9707_00770 0.0 1146.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,27DKA@186827|Aerococcaceae 91061|Bacilli M Transglycosylase pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase gnl|extdb|FAM24227-i1-1.1_000664 592010.GCWU000182_001279 0.0 1005.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,27DJS@186827|Aerococcaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr gnl|extdb|FAM24227-i1-1.1_000669 1123359.AUIQ01000047_gene432 1.89e-134 397.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,4AZ9I@81852|Enterococcaceae 91061|Bacilli E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 gnl|extdb|FAM24227-i1-1.1_000670 592010.GCWU000182_001239 0.0 901.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,27DCK@186827|Aerococcaceae 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 gnl|extdb|FAM24227-i1-1.1_000671 1408438.JADD01000003_gene232 1.72e-208 584.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,27DEJ@186827|Aerococcaceae 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase gnl|extdb|FAM24227-i1-1.1_000673 1408438.JADD01000003_gene234 2.05e-271 751.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,27DC7@186827|Aerococcaceae 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_000674 883112.HMPREF9707_00360 0.0 933.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,27DFG@186827|Aerococcaceae 91061|Bacilli M Penicillin-binding protein, 1A family pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase gnl|extdb|FAM24227-i1-1.1_000675 1121871.AUAT01000033_gene1792 1.19e-36 127.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HPJM@91061|Bacilli,27E5I@186827|Aerococcaceae 91061|Bacilli S Belongs to the UPF0342 family XK26_04240 - - - - - - - - - - - Com_YlbF gnl|extdb|FAM24227-i1-1.1_000676 592010.GCWU000182_001195 2.29e-130 389.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,27DND@186827|Aerococcaceae 91061|Bacilli L Calcineurin-like phosphoesterase superfamily domain yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 gnl|extdb|FAM24227-i1-1.1_000677 592010.GCWU000182_001196 4.94e-294 846.0 COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,27DHP@186827|Aerococcaceae 91061|Bacilli D AAA domain yhaN - - - - - - - - - - - AAA_27 gnl|extdb|FAM24227-i1-1.1_000678 1408438.JADD01000003_gene239 7.19e-174 491.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,27DQM@186827|Aerococcaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon gnl|extdb|FAM24227-i1-1.1_000679 1405.DJ92_5107 5.34e-21 92.0 COG3832@1|root,COG3832@2|Bacteria,1V83M@1239|Firmicutes,4HJFK@91061|Bacilli,1ZHAR@1386|Bacillus 91061|Bacilli S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 gnl|extdb|FAM24227-i1-1.1_000680 1158601.I585_02804 9.55e-257 718.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,4B0HZ@81852|Enterococcaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase gnl|extdb|FAM24227-i1-1.1_000682 1201292.DR75_1737 1.81e-159 454.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HDHJ@91061|Bacilli,4B6AA@81852|Enterococcaceae 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase gnl|extdb|FAM24227-i1-1.1_000684 1175629.AJTG01000031_gene1507 0.0 1192.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,27ET1@186827|Aerococcaceae 91061|Bacilli L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII gnl|extdb|FAM24227-i1-1.1_000685 655812.HMPREF0061_0970 0.0 1327.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli,27DIR@186827|Aerococcaceae 91061|Bacilli S Hemerythrin HHE cation binding domain protein XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 gnl|extdb|FAM24227-i1-1.1_000686 655812.HMPREF0061_0971 6.98e-53 166.0 COG2461@1|root,COG2461@2|Bacteria,1VIMF@1239|Firmicutes,4HQ0V@91061|Bacilli,27E6F@186827|Aerococcaceae 91061|Bacilli S Domain of unknown function (DUF1858) - - - - - - - - - - - - DUF1858 gnl|extdb|FAM24227-i1-1.1_000687 655812.HMPREF0061_0972 2.48e-80 238.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,27E2P@186827|Aerococcaceae 91061|Bacilli S Pfam:DUF59 yitW - - - - - - - - - - - FeS_assembly_P gnl|extdb|FAM24227-i1-1.1_000688 655812.HMPREF0061_0973 0.0 1498.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli,27DEU@186827|Aerococcaceae 91061|Bacilli C Pyruvate formate lyase-like pflB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like gnl|extdb|FAM24227-i1-1.1_000689 655812.HMPREF0061_0974 8.97e-190 527.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli,27DK8@186827|Aerococcaceae 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM gnl|extdb|FAM24227-i1-1.1_000690 655812.HMPREF0061_0975 0.0 1725.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,27DCM@186827|Aerococcaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - iSB619.SA_RS00885 Aldedh,Fe-ADH gnl|extdb|FAM24227-i1-1.1_000691 1232666.JANE01000007_gene1643 1.97e-45 155.0 COG3631@1|root,COG3631@2|Bacteria,1VC7Y@1239|Firmicutes,4HMVN@91061|Bacilli,4H1I1@90964|Staphylococcaceae 91061|Bacilli S Ketosteroid isomerase-related protein - - - - - - - - - - - - SnoaL_2 gnl|extdb|FAM24227-i1-1.1_000692 1158608.I583_03217 2.4e-91 287.0 2DSXT@1|root,32UTZ@2|Bacteria,1U54P@1239|Firmicutes,4IEVW@91061|Bacilli,4AZBX@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000693 908337.HMPREF9257_1576 4.24e-95 300.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HE2R@91061|Bacilli 91061|Bacilli S Calcineurin-like phosphoesterase - - 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos gnl|extdb|FAM24227-i1-1.1_000694 1232428.CAVO010000069_gene466 8.9e-68 220.0 COG0679@1|root,COG0679@2|Bacteria,1V0ZS@1239|Firmicutes,4H4ZG@909932|Negativicutes 909932|Negativicutes S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans gnl|extdb|FAM24227-i1-1.1_000695 698758.AXY_13120 3.48e-94 293.0 COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,4HGFS@91061|Bacilli 91061|Bacilli S hmm pf01594 XK27_12525 - - - - - - - - - - - AI-2E_transport gnl|extdb|FAM24227-i1-1.1_000696 883113.HMPREF9708_00309 1.58e-173 501.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,27DWD@186827|Aerococcaceae 91061|Bacilli V Polysaccharide biosynthesis C-terminal domain dinF - - - - - - - - - - - MatE gnl|extdb|FAM24227-i1-1.1_000697 357809.Cphy_1008 2e-83 256.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24BUT@186801|Clostridia,21Y7J@1506553|Lachnoclostridium 186801|Clostridia K TipAS antibiotic-recognition domain protein - - - - - - - - - - - - MerR_1,TipAS gnl|extdb|FAM24227-i1-1.1_000699 1449335.JQLG01000004_gene1589 4.62e-63 196.0 COG0346@1|root,COG0346@2|Bacteria,1V6FU@1239|Firmicutes,4HIRR@91061|Bacilli,27GMQ@186828|Carnobacteriaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K07032 - - - - ko00000 - - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_000700 1121871.AUAT01000005_gene1728 0.0 1106.0 COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli,27DM1@186827|Aerococcaceae 91061|Bacilli F Anaerobic ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD gnl|extdb|FAM24227-i1-1.1_000702 1408438.JADD01000002_gene329 1.09e-86 265.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,27EFX@186827|Aerococcaceae 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N gnl|extdb|FAM24227-i1-1.1_000703 1122128.AUEE01000003_gene654 1.18e-53 172.0 COG1846@1|root,COG1846@2|Bacteria,1V6EE@1239|Firmicutes,4HJ8T@91061|Bacilli,4GZ5H@90964|Staphylococcaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - ko:K15973 - - - - ko00000,ko03000 - - - MarR gnl|extdb|FAM24227-i1-1.1_000704 1461582.BN1048_01511 8.25e-180 506.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,4GYC1@90964|Staphylococcaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mhqA_2 - - ko:K15975 - - - - ko00000 - - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_000705 1078083.HMPREF1208_01682 4.19e-117 346.0 COG0346@1|root,COG0346@2|Bacteria,1TQCN@1239|Firmicutes,4HAMC@91061|Bacilli,4GYPN@90964|Staphylococcaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mhqO - - ko:K15975 - - - - ko00000 - - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_000706 224308.BSU36080 1.67e-63 202.0 COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,1ZB1C@1386|Bacillus 91061|Bacilli S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family ywrF - - - - - - - - - - - Flavin_Reduct gnl|extdb|FAM24227-i1-1.1_000707 1123306.KB904339_gene155 4.52e-76 234.0 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli 91061|Bacilli S Carboxylesterase mhqD - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH gnl|extdb|FAM24227-i1-1.1_000708 888056.HMPREF9062_1491 7.34e-37 136.0 2DQNU@1|root,337U8@2|Bacteria,2I841@201174|Actinobacteria 201174|Actinobacteria S Integral membrane protein (intg_mem_TP0381) - - - - - - - - - - - - Intg_mem_TP0381 gnl|extdb|FAM24227-i1-1.1_000709 1408438.JADD01000003_gene159 1.67e-23 93.2 COG4828@1|root,COG4828@2|Bacteria,1VACG@1239|Firmicutes,4HZDZ@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1622) - - - - - - - - - - - - DUF1622 gnl|extdb|FAM24227-i1-1.1_000710 208596.CAR_c01650 2.36e-52 169.0 COG2764@1|root,COG2764@2|Bacteria,1V1HM@1239|Firmicutes,4HVUG@91061|Bacilli,27HVY@186828|Carnobacteriaceae 91061|Bacilli S glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000711 202752.JL53_10950 9.55e-194 548.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,26K5H@186820|Listeriaceae 91061|Bacilli E Peptidase dimerisation domain amd - - - - - - - - - - - M20_dimer,Peptidase_M20 gnl|extdb|FAM24227-i1-1.1_000712 883112.HMPREF9707_01404 1.34e-163 469.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C gnl|extdb|FAM24227-i1-1.1_000713 883112.HMPREF9707_01405 2.44e-56 178.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli 91061|Bacilli E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H gnl|extdb|FAM24227-i1-1.1_000714 883112.HMPREF9707_01406 4.5e-240 669.0 COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P gnl|extdb|FAM24227-i1-1.1_000715 883112.HMPREF9707_01407 1.47e-260 725.0 COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P gnl|extdb|FAM24227-i1-1.1_000716 33035.JPJF01000009_gene1471 1.12e-38 137.0 COG0454@1|root,COG0456@2|Bacteria,1V7I8@1239|Firmicutes,24G1V@186801|Clostridia 186801|Clostridia K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 gnl|extdb|FAM24227-i1-1.1_000717 981383.AEWH01000041_gene3573 2.81e-75 233.0 COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli 91061|Bacilli Q dithiol-disulfide isomerase involved in polyketide biosynthesis frnE - - - - - - - - - - - DSBA gnl|extdb|FAM24227-i1-1.1_000718 1408438.JADD01000002_gene327 9.58e-138 410.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli 91061|Bacilli S ErfK YbiS YcfS YnhG - - - - - - - - - - - - PG_binding_4,YkuD gnl|extdb|FAM24227-i1-1.1_000719 1408438.JADD01000002_gene326 5.19e-127 376.0 COG4129@1|root,COG4129@2|Bacteria,1TPVH@1239|Firmicutes,4HAEG@91061|Bacilli,27DY4@186827|Aerococcaceae 91061|Bacilli S Fusaric acid resistance protein-like ygaE - - - - - - - - - - - ArAE_1 gnl|extdb|FAM24227-i1-1.1_000720 1408438.JADD01000002_gene323 3.04e-179 505.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,27DIQ@186827|Aerococcaceae 91061|Bacilli J tRNA synthetases class I (W and Y) trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b gnl|extdb|FAM24227-i1-1.1_000721 1408438.JADD01000002_gene322 1.32e-78 236.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,27DYC@186827|Aerococcaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC gnl|extdb|FAM24227-i1-1.1_000722 883113.HMPREF9708_00452 1.06e-74 233.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli,27E1I@186827|Aerococcaceae 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA gnl|extdb|FAM24227-i1-1.1_000723 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_000672 883113.HMPREF9708_00212 1.01e-133 394.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,27DPP@186827|Aerococcaceae 91061|Bacilli G glucose-1-phosphate adenylyltransferase glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase gnl|extdb|FAM24227-i1-1.1_000681 293826.Amet_1608 1.77e-77 244.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,24DRR@186801|Clostridia,36H37@31979|Clostridiaceae 186801|Clostridia V PFAM restriction modification system DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S gnl|extdb|FAM24227-i1-1.1_000683 1074451.CRL705_317 2.04e-99 307.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,4HGJM@91061|Bacilli,3FB4X@33958|Lactobacillaceae 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S gnl|extdb|FAM24227-i1-1.1_000701 1121871.AUAT01000005_gene1727 1.11e-113 328.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli,27DNX@186827|Aerococcaceae 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM gnl|extdb|FAM24227-i1-1.1_000724 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_000725 883110.HMPREF9260_00907 5.11e-133 421.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,27E0C@186827|Aerococcaceae 91061|Bacilli S DNA internalization competence protein ComEC Rec2-like protein comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B gnl|extdb|FAM24227-i1-1.1_000726 883113.HMPREF9708_01126 1.02e-40 146.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,27E41@186827|Aerococcaceae 91061|Bacilli L SLBB domain comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB gnl|extdb|FAM24227-i1-1.1_000727 1408438.JADD01000011_gene1591 9.38e-69 213.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,27E3N@186827|Aerococcaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like gnl|extdb|FAM24227-i1-1.1_000728 592010.GCWU000182_001307 1.26e-72 224.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,27DY5@186827|Aerococcaceae 91061|Bacilli L RNA methyltransferase, RsmD family rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 gnl|extdb|FAM24227-i1-1.1_000729 883112.HMPREF9707_01577 2.38e-29 109.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,27E62@186827|Aerococcaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2129) ylbG - - - - - - - - - - - DUF2129 gnl|extdb|FAM24227-i1-1.1_000730 883112.HMPREF9707_01576 2.69e-87 278.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,27E0U@186827|Aerococcaceae 91061|Bacilli D Cell cycle protein, FtsW RodA SpoVE family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE gnl|extdb|FAM24227-i1-1.1_000731 1121871.AUAT01000011_gene504 8.71e-111 322.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,27DUT@186827|Aerococcaceae 91061|Bacilli P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0005575,GO:0005576 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N gnl|extdb|FAM24227-i1-1.1_000733 1408438.JADD01000011_gene1581 9.14e-118 344.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,27DVY@186827|Aerococcaceae 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P gnl|extdb|FAM24227-i1-1.1_000734 888821.HMPREF9394_1530 8.72e-26 99.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,1WRW4@1305|Streptococcus sanguinis 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 gnl|extdb|FAM24227-i1-1.1_000735 1229520.ADIAL_0732 1.93e-87 270.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,27G8F@186828|Carnobacteriaceae 91061|Bacilli K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate gnl|extdb|FAM24227-i1-1.1_000737 1229520.ADIAL_0730 1.75e-94 283.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,27G5B@186828|Carnobacteriaceae 91061|Bacilli M LrgB-like family lrgB - - ko:K05339 ko02020,map02020 - - - ko00000,ko00001 - - - LrgB gnl|extdb|FAM24227-i1-1.1_000738 883112.HMPREF9707_00185 9.98e-233 644.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,27EG1@186827|Aerococcaceae 91061|Bacilli C FMN-dependent dehydrogenase lldD - 1.13.12.4 ko:K00467,ko:K10530 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh gnl|extdb|FAM24227-i1-1.1_000739 1175629.AJTG01000003_gene894 2.18e-84 252.0 COG3542@1|root,COG3542@2|Bacteria,1V52Y@1239|Firmicutes,4HH9T@91061|Bacilli,27ETS@186827|Aerococcaceae 91061|Bacilli S Cupin superfamily (DUF985) - - - ko:K09705 - - - - ko00000 - - - Cupin_5 gnl|extdb|FAM24227-i1-1.1_000741 1121871.AUAT01000011_gene510 7.27e-37 130.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,27E3U@186827|Aerococcaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N gnl|extdb|FAM24227-i1-1.1_000742 908337.HMPREF9257_0329 6.3e-277 766.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,27EF2@186827|Aerococcaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N gnl|extdb|FAM24227-i1-1.1_000743 908337.HMPREF9257_0330 9.16e-99 300.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,27DVS@186827|Aerococcaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt gnl|extdb|FAM24227-i1-1.1_000744 908337.HMPREF9257_0331 5.07e-250 699.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,27EJA@186827|Aerococcaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N gnl|extdb|FAM24227-i1-1.1_000745 5888.CAK62730 2.47e-05 49.3 COG0712@1|root,KOG1662@2759|Eukaryota,3ZBUG@5878|Ciliophora 5878|Ciliophora C ATP synthase delta (OSCP) subunit - - - ko:K02137 ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016 M00158 - - ko00000,ko00001,ko00002 3.A.2.1 - - OSCP gnl|extdb|FAM24227-i1-1.1_000746 908337.HMPREF9257_0333 1.23e-13 72.4 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,27EWB@186827|Aerococcaceae 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B gnl|extdb|FAM24227-i1-1.1_000747 1121871.AUAT01000011_gene516 3.03e-27 100.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,27EW7@186827|Aerococcaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C gnl|extdb|FAM24227-i1-1.1_000748 908337.HMPREF9257_0335 6.6e-88 267.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,27EMU@186827|Aerococcaceae 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A gnl|extdb|FAM24227-i1-1.1_000749 1121871.AUAT01000011_gene518 2.52e-290 798.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,27DCZ@186827|Aerococcaceae 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim gnl|extdb|FAM24227-i1-1.1_000750 1408438.JADD01000011_gene1556 2.82e-255 716.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,27DM4@186827|Aerococcaceae 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding gnl|extdb|FAM24227-i1-1.1_000751 1121871.AUAT01000011_gene520 2.55e-204 568.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,27DT5@186827|Aerococcaceae 91061|Bacilli C Transketolase, pyrimidine binding domain pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14590 Transket_pyr,Transketolase_C gnl|extdb|FAM24227-i1-1.1_000752 883112.HMPREF9707_01568 2.14e-227 630.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,27DF0@186827|Aerococcaceae 91061|Bacilli C Pyruvate dehydrogenase E1 component, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh gnl|extdb|FAM24227-i1-1.1_000754 883103.HMPREF9703_00330 1.18e-124 364.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,27FYI@186828|Carnobacteriaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans gnl|extdb|FAM24227-i1-1.1_000755 592010.GCWU000182_001124 1.53e-241 674.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,27F6A@186827|Aerococcaceae 91061|Bacilli I acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 gnl|extdb|FAM24227-i1-1.1_000756 592010.GCWU000182_001123 1.65e-81 243.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,27E4M@186827|Aerococcaceae 91061|Bacilli I FabA-like domain fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA gnl|extdb|FAM24227-i1-1.1_000757 883103.HMPREF9703_00333 1.54e-40 140.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,27GN2@186828|Carnobacteriaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl gnl|extdb|FAM24227-i1-1.1_000758 883103.HMPREF9703_00334 2.28e-224 627.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27FKS@186828|Carnobacteriaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt gnl|extdb|FAM24227-i1-1.1_000759 1408438.JADD01000011_gene1544 1.13e-121 352.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,27DVV@186827|Aerococcaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 gnl|extdb|FAM24227-i1-1.1_000760 592010.GCWU000182_001119 2.23e-98 299.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,27E1P@186827|Aerococcaceae 91061|Bacilli I Acyl transferase domain fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 gnl|extdb|FAM24227-i1-1.1_000761 1408438.JADD01000011_gene1542 1.02e-162 463.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,27DEP@186827|Aerococcaceae 91061|Bacilli S enoyl- acyl-carrier-protein reductase II fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO gnl|extdb|FAM24227-i1-1.1_000762 1408438.JADD01000011_gene1541 1.53e-27 101.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli,27E9X@186827|Aerococcaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding gnl|extdb|FAM24227-i1-1.1_000763 592010.GCWU000182_001116 1.75e-107 322.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,27EAJ@186827|Aerococcaceae 91061|Bacilli I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C gnl|extdb|FAM24227-i1-1.1_000764 883103.HMPREF9703_00340 6.56e-64 199.0 COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4HIMR@91061|Bacilli,27GA1@186828|Carnobacteriaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein XK27_02735 - - - - - - - - - - - MarR gnl|extdb|FAM24227-i1-1.1_000765 908337.HMPREF9257_0345 2.83e-215 606.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,27DFM@186827|Aerococcaceae 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N gnl|extdb|FAM24227-i1-1.1_000766 1121024.AUCD01000017_gene622 1.82e-63 200.0 COG0454@1|root,COG0456@2|Bacteria,1V6YX@1239|Firmicutes,4HJS1@91061|Bacilli,27GFU@186828|Carnobacteriaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 gnl|extdb|FAM24227-i1-1.1_000768 1408438.JADD01000015_gene788 1.94e-89 266.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HHMA@91061|Bacilli,27F4A@186827|Aerococcaceae 91061|Bacilli J Polypeptide deformylase - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase gnl|extdb|FAM24227-i1-1.1_000769 883110.HMPREF9260_00927 3.36e-172 494.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,27DSK@186827|Aerococcaceae 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 gnl|extdb|FAM24227-i1-1.1_000770 883112.HMPREF9707_01555 7.63e-138 399.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,27DIX@186827|Aerococcaceae 91061|Bacilli H Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT gnl|extdb|FAM24227-i1-1.1_000771 592010.GCWU000182_000501 2.47e-185 541.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,27DMF@186827|Aerococcaceae 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N gnl|extdb|FAM24227-i1-1.1_000772 592010.GCWU000182_000502 3.78e-135 389.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,27DE4@186827|Aerococcaceae 91061|Bacilli J ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 gnl|extdb|FAM24227-i1-1.1_000773 1121871.AUAT01000011_gene533 3.13e-104 313.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,27DSU@186827|Aerococcaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt gnl|extdb|FAM24227-i1-1.1_000774 1408438.JADD01000015_gene782 8.69e-23 89.7 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,27E7D@186827|Aerococcaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S gnl|extdb|FAM24227-i1-1.1_000775 908337.HMPREF9257_0354 5.52e-148 437.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,27DCY@186827|Aerococcaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 gnl|extdb|FAM24227-i1-1.1_000776 883112.HMPREF9707_01549 1.97e-111 331.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,27DX2@186827|Aerococcaceae 91061|Bacilli H Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C gnl|extdb|FAM24227-i1-1.1_000777 883112.HMPREF9707_01548 7.59e-143 432.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,27DTW@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1002) - - - - - - - - - - - - DUF1002 gnl|extdb|FAM24227-i1-1.1_000778 883112.HMPREF9707_01547 2.92e-44 150.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,27E82@186827|Aerococcaceae 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB gnl|extdb|FAM24227-i1-1.1_000779 592010.GCWU000182_000313 3.43e-38 133.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,27E7B@186827|Aerococcaceae 91061|Bacilli S Asp23 family, cell envelope-related function WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 gnl|extdb|FAM24227-i1-1.1_000780 883112.HMPREF9707_01545 6.39e-161 461.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,27DNJ@186827|Aerococcaceae 91061|Bacilli E Belongs to the peptidase M24B family pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 gnl|extdb|FAM24227-i1-1.1_000784 1408438.JADD01000015_gene768 2.63e-17 80.5 COG4970@1|root,COG4970@2|Bacteria,1VBS8@1239|Firmicutes,4HKPK@91061|Bacilli,27EZ7@186827|Aerococcaceae 91061|Bacilli NU overlaps another CDS with the same product name comGD - - ko:K02246 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl gnl|extdb|FAM24227-i1-1.1_000785 883110.HMPREF9260_00943 6.98e-25 97.4 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,27E7H@186827|Aerococcaceae 91061|Bacilli U overlaps another CDS with the same product name comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl gnl|extdb|FAM24227-i1-1.1_000786 883112.HMPREF9707_01539 8.65e-115 344.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,27E40@186827|Aerococcaceae 91061|Bacilli NU Bacterial type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF gnl|extdb|FAM24227-i1-1.1_000787 1121871.AUAT01000011_gene546 5.4e-142 412.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,27DIW@186827|Aerococcaceae 91061|Bacilli NU Type II/IV secretion system protein comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE gnl|extdb|FAM24227-i1-1.1_000788 1408438.JADD01000015_gene772 1.25e-22 89.4 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,27E69@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1447) ykzG - - - - - - - - - - - DUF1447 gnl|extdb|FAM24227-i1-1.1_000789 908337.HMPREF9257_0367 0.0 952.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,27DNR@186827|Aerococcaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL gnl|extdb|FAM24227-i1-1.1_000790 1408438.JADD01000015_gene780 4.69e-32 120.0 28H7K@1|root,2Z7JT@2|Bacteria,1UPH1@1239|Firmicutes,4HE88@91061|Bacilli 91061|Bacilli P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system - - - ko:K02526 - - - - ko00000,ko02000 2.A.10.1 - - KdgT gnl|extdb|FAM24227-i1-1.1_000732 592010.GCWU000182_000029 0.0 996.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,27DQP@186827|Aerococcaceae 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 gnl|extdb|FAM24227-i1-1.1_000736 1229520.ADIAL_0096 7.29e-39 134.0 COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,4HKWV@91061|Bacilli,27GP8@186828|Carnobacteriaceae 91061|Bacilli S LrgA family lrgA - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA gnl|extdb|FAM24227-i1-1.1_000753 592010.GCWU000182_001126 1.69e-112 331.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,27DVH@186827|Aerococcaceae 91061|Bacilli I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA gnl|extdb|FAM24227-i1-1.1_000782 883112.HMPREF9707_01543 1.58e-24 99.0 COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli,27EVT@186827|Aerococcaceae 91061|Bacilli U Putative Competence protein ComGF comGF - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl gnl|extdb|FAM24227-i1-1.1_000791 883113.HMPREF9708_01421 4.49e-83 255.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,27ES1@186827|Aerococcaceae 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_000792 1234679.BN424_1095 9.15e-92 280.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,27FDZ@186828|Carnobacteriaceae 91061|Bacilli G Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N gnl|extdb|FAM24227-i1-1.1_000793 1408438.JADD01000005_gene1153 0.0 946.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,27DPN@186827|Aerococcaceae 91061|Bacilli P Copper-exporting ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase gnl|extdb|FAM24227-i1-1.1_000794 795797.C497_01835 1.82e-11 65.1 COG2217@1|root,arCOG02763@1|root,arCOG01576@2157|Archaea,arCOG02763@2157|Archaea,2XT3T@28890|Euryarchaeota,23SUI@183963|Halobacteria 183963|Halobacteria P COG2217 Cation transport ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase gnl|extdb|FAM24227-i1-1.1_000795 1121871.AUAT01000007_gene1647 1.99e-48 160.0 COG3682@1|root,COG3682@2|Bacteria,1TUSB@1239|Firmicutes,4HXVN@91061|Bacilli,27EU1@186827|Aerococcaceae 91061|Bacilli K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R gnl|extdb|FAM24227-i1-1.1_000796 1121871.AUAT01000007_gene1648 1.12e-59 186.0 COG1780@1|root,COG1780@2|Bacteria,1V9T1@1239|Firmicutes,4HJ0M@91061|Bacilli,27E2T@186827|Aerococcaceae 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI gnl|extdb|FAM24227-i1-1.1_000798 908337.HMPREF9257_1091 4.07e-222 616.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,27DI1@186827|Aerococcaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm gnl|extdb|FAM24227-i1-1.1_000799 883113.HMPREF9708_01216 1.65e-08 63.5 COG1196@1|root,COG1196@2|Bacteria,1U58B@1239|Firmicutes,4I1NA@91061|Bacilli,27F0X@186827|Aerococcaceae 91061|Bacilli D Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 gnl|extdb|FAM24227-i1-1.1_000801 1121024.AUCD01000024_gene749 8.31e-221 624.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,27GZC@186828|Carnobacteriaceae 91061|Bacilli G Glucose-6-phosphate dehydrogenase, NAD binding domain zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N gnl|extdb|FAM24227-i1-1.1_000802 1408438.JADD01000005_gene1158 9.26e-39 139.0 2EEMW@1|root,338FS@2|Bacteria,1VI19@1239|Firmicutes,4HPGX@91061|Bacilli,27E7W@186827|Aerococcaceae 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 gnl|extdb|FAM24227-i1-1.1_000803 1408438.JADD01000005_gene1159 4.08e-52 170.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,27E4I@186827|Aerococcaceae 91061|Bacilli S Hydrolase, P-loop family ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE gnl|extdb|FAM24227-i1-1.1_000804 883113.HMPREF9708_00912 4.9e-58 187.0 COG1670@1|root,COG1670@2|Bacteria,1UN7V@1239|Firmicutes,4IU75@91061|Bacilli,27E2Y@186827|Aerococcaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 gnl|extdb|FAM24227-i1-1.1_000805 883112.HMPREF9707_00235 1.88e-132 385.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,27DKJ@186827|Aerococcaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C gnl|extdb|FAM24227-i1-1.1_000806 1319815.HMPREF0202_02106 2.63e-158 458.0 COG0183@1|root,COG0183@2|Bacteria,378R0@32066|Fusobacteria 32066|Fusobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N gnl|extdb|FAM24227-i1-1.1_000808 883112.HMPREF9707_00237 1.41e-133 385.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli,27DJR@186827|Aerococcaceae 91061|Bacilli E Binding-protein-dependent transport system inner membrane component potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000809 883112.HMPREF9707_00238 4.33e-134 387.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,27EFC@186827|Aerococcaceae 91061|Bacilli E Binding-protein-dependent transport system inner membrane component potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000810 883112.HMPREF9707_00239 4.12e-185 523.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli,27EE2@186827|Aerococcaceae 91061|Bacilli E Bacterial extracellular solute-binding protein potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 gnl|extdb|FAM24227-i1-1.1_000812 1408438.JADD01000005_gene1164 1.07e-44 150.0 COG2246@1|root,COG2246@2|Bacteria,1VDQH@1239|Firmicutes,4HNPD@91061|Bacilli,27E28@186827|Aerococcaceae 91061|Bacilli S GtrA-like protein - - - - - - - - - - - - GtrA gnl|extdb|FAM24227-i1-1.1_000813 1408438.JADD01000005_gene1165 4.17e-153 438.0 COG1216@1|root,COG1216@2|Bacteria,1UHWE@1239|Firmicutes,4ISA4@91061|Bacilli,27F69@186827|Aerococcaceae 91061|Bacilli M Glycosyltransferase like family 2 yfdH - - ko:K12999 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 gnl|extdb|FAM24227-i1-1.1_000814 883112.HMPREF9707_01162 4.89e-82 250.0 2DMUC@1|root,32TQR@2|Bacteria,1V9Y3@1239|Firmicutes,4HSUC@91061|Bacilli,27E3Y@186827|Aerococcaceae 91061|Bacilli S CpXC protein - - - - - - - - - - - - CpXC gnl|extdb|FAM24227-i1-1.1_000815 1408438.JADD01000005_gene1167 5.79e-104 306.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,27DV5@186827|Aerococcaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A gnl|extdb|FAM24227-i1-1.1_000816 883112.HMPREF9707_01164 5.29e-221 620.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,27EJ2@186827|Aerococcaceae 91061|Bacilli F Pyrimidine nucleoside phosphorylase C-terminal domain pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C gnl|extdb|FAM24227-i1-1.1_000817 1121871.AUAT01000012_gene620 1.11e-153 443.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,27DJ8@186827|Aerococcaceae 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh gnl|extdb|FAM24227-i1-1.1_000818 1408438.JADD01000005_gene1171 2.71e-82 263.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HC93@91061|Bacilli,27DW0@186827|Aerococcaceae 91061|Bacilli I GHMP kinases C terminal mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N gnl|extdb|FAM24227-i1-1.1_000820 1408438.JADD01000005_gene1173 4.07e-133 389.0 COG1577@1|root,COG1577@2|Bacteria,1TT5C@1239|Firmicutes,4HAQQ@91061|Bacilli,27DJG@186827|Aerococcaceae 91061|Bacilli I GHMP kinases C terminal mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N gnl|extdb|FAM24227-i1-1.1_000821 592010.GCWU000182_001579 9.2e-123 361.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,27DF7@186827|Aerococcaceae 91061|Bacilli H Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK gnl|extdb|FAM24227-i1-1.1_000822 1408438.JADD01000005_gene1175 2.18e-313 860.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,27DS7@186827|Aerococcaceae 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase gnl|extdb|FAM24227-i1-1.1_000823 883103.HMPREF9703_00018 1.21e-94 288.0 COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli,27GBY@186828|Carnobacteriaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD gnl|extdb|FAM24227-i1-1.1_000824 592010.GCWU000182_000010 1.98e-94 287.0 COG0834@1|root,COG0834@2|Bacteria,1UHHG@1239|Firmicutes,4H9NX@91061|Bacilli,27EPD@186827|Aerococcaceae 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins yckB - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_000826 1121871.AUAT01000006_gene1563 4.42e-279 780.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27DH0@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein mdlA - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_000827 908337.HMPREF9257_1537 9.28e-287 800.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27DH5@186827|Aerococcaceae 91061|Bacilli V ABC transporter transmembrane region mdlB - - ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_000828 1408438.JADD01000013_gene1691 1.68e-255 709.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,27EAH@186827|Aerococcaceae 91061|Bacilli S Pyridine nucleotide-disulphide oxidoreductase npr - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim gnl|extdb|FAM24227-i1-1.1_000829 1123302.KB904157_gene1390 1.12e-174 495.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli 91061|Bacilli E Aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 gnl|extdb|FAM24227-i1-1.1_000830 1123359.AUIQ01000039_gene352 2.92e-101 301.0 COG3971@1|root,COG3971@2|Bacteria,1TQVG@1239|Firmicutes,4HBMC@91061|Bacilli,4B5BR@81852|Enterococcaceae 91061|Bacilli Q hydratase mhpD - - ko:K02509 ko00350,ko01120,map00350,map01120 - R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 - - - - gnl|extdb|FAM24227-i1-1.1_000831 1408438.JADD01000011_gene1597 1.42e-132 392.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27DIN@186827|Aerococcaceae 91061|Bacilli E Receptor family ligand-binding protein livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 gnl|extdb|FAM24227-i1-1.1_000832 866775.HMPREF9243_0722 1.31e-33 120.0 COG2340@1|root,COG2340@2|Bacteria,1VNRY@1239|Firmicutes,4I63G@91061|Bacilli,27F0Y@186827|Aerococcaceae 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP gnl|extdb|FAM24227-i1-1.1_000833 1408438.JADD01000032_gene1326 6.19e-07 59.3 COG1388@1|root,COG3087@1|root,COG1388@2|Bacteria,COG3087@2|Bacteria,1UMAB@1239|Firmicutes 1239|Firmicutes D Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000835 1415774.U728_1183 2.62e-14 81.6 29X0C@1|root,30INM@2|Bacteria,1UJ9D@1239|Firmicutes,24DBZ@186801|Clostridia,36ESZ@31979|Clostridiaceae 186801|Clostridia S Anti-sigma factor N-terminus - - - - - - - - - - - - RsgI_N gnl|extdb|FAM24227-i1-1.1_000836 1033739.CAEU01000023_gene3055 0.000523 48.9 COG3212@1|root,COG3212@2|Bacteria,1VIP2@1239|Firmicutes,4HPJE@91061|Bacilli,26HPY@186818|Planococcaceae 91061|Bacilli S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY gnl|extdb|FAM24227-i1-1.1_000837 1266845.Q783_01845 8.74e-102 302.0 COG2761@1|root,COG2761@2|Bacteria,1V2DY@1239|Firmicutes,4HFWR@91061|Bacilli 91061|Bacilli Q DSBA-like thioredoxin domain - - - - - - - - - - - - DSBA,Thioredoxin_5 gnl|extdb|FAM24227-i1-1.1_000838 698758.AXY_07840 8.98e-43 145.0 2E69S@1|root,330XP@2|Bacteria,1VA0C@1239|Firmicutes,4HMQ0@91061|Bacilli 91061|Bacilli S Lipocalin-like domain - - - - - - - - - - - - Lipocalin_5 gnl|extdb|FAM24227-i1-1.1_000839 866775.HMPREF9243_1274 1.27e-147 425.0 COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,4H9TE@91061|Bacilli,27F1U@186827|Aerococcaceae 91061|Bacilli E Diaminopimelic acid dehydrogenase C-terminal domain - - 1.4.1.16 ko:K03340 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00526 R02755 RC00006 ko00000,ko00001,ko00002,ko01000 - - - DAPDH_C,DapB_N gnl|extdb|FAM24227-i1-1.1_000840 1140002.I570_01160 3.11e-154 442.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HDXF@91061|Bacilli,4B1SR@81852|Enterococcaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C gnl|extdb|FAM24227-i1-1.1_000841 1121864.OMO_02334 6.18e-186 523.0 COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,4HBHI@91061|Bacilli,4B1YB@81852|Enterococcaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain yhhX - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C gnl|extdb|FAM24227-i1-1.1_000842 655812.HMPREF0061_0573 3.04e-114 340.0 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,27EV0@186827|Aerococcaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA gnl|extdb|FAM24227-i1-1.1_000843 1301100.HG529329_gene4480 1.12e-31 111.0 COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,24QNU@186801|Clostridia,36MN1@31979|Clostridiaceae 186801|Clostridia S Uncharacterized conserved protein (DUF2196) - - - - - - - - - - - - DUF2196 gnl|extdb|FAM24227-i1-1.1_000844 1304866.K413DRAFT_4932 4e-63 203.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia,36EYH@31979|Clostridiaceae 186801|Clostridia S MgtC SapB transporter - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC gnl|extdb|FAM24227-i1-1.1_000845 333138.LQ50_16040 1.63e-69 216.0 28PN2@1|root,2ZCAV@2|Bacteria,1V2C1@1239|Firmicutes,4HGS6@91061|Bacilli,1ZG8V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000846 1713.JOFV01000018_gene213 7.07e-21 88.2 2EJRI@1|root,32U8K@2|Bacteria,2IT18@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - DUF1801 gnl|extdb|FAM24227-i1-1.1_000797 1121871.AUAT01000007_gene1649 0.0 1259.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,27DH1@186827|Aerococcaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN gnl|extdb|FAM24227-i1-1.1_000800 883112.HMPREF9707_00231 6.46e-182 512.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,27DDV@186827|Aerococcaceae 91061|Bacilli C Phosphate acetyl/butaryl transferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB gnl|extdb|FAM24227-i1-1.1_000807 592010.GCWU000182_000480 7.86e-218 606.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,27DBQ@186827|Aerococcaceae 91061|Bacilli E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 gnl|extdb|FAM24227-i1-1.1_000819 883112.HMPREF9707_01168 2.02e-137 399.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,27DJ5@186827|Aerococcaceae 91061|Bacilli I GHMP kinases N terminal domain mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N gnl|extdb|FAM24227-i1-1.1_000825 1087448.Eab7_1580 9.4e-84 256.0 COG0765@1|root,COG0765@2|Bacteria,1TQ43@1239|Firmicutes,4HCZV@91061|Bacilli,3WFZ3@539002|Bacillales incertae sedis 91061|Bacilli P TIGRFAM polar amino acid ABC transporter, inner membrane subunit yckA GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_000834 1408438.JADD01000006_gene970 1.21e-65 208.0 COG1191@1|root,COG1191@2|Bacteria,1V5E6@1239|Firmicutes,4HEBS@91061|Bacilli 91061|Bacilli K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigI - - ko:K03093 - - - - ko00000,ko03021 - - - Sigma70_r2 gnl|extdb|FAM24227-i1-1.1_000847 586413.CCDL010000001_gene1244 9.89e-97 287.0 COG4912@1|root,COG4912@2|Bacteria,1UP0J@1239|Firmicutes,4HDFV@91061|Bacilli,23J7Q@182709|Oceanobacillus 91061|Bacilli L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation gnl|extdb|FAM24227-i1-1.1_000848 1229520.ADIAL_1129 7.13e-172 497.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,27G3I@186828|Carnobacteriaceae 91061|Bacilli C Aldehyde dehydrogenase family aldH - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh gnl|extdb|FAM24227-i1-1.1_000849 638301.HMPREF0444_1643 4.21e-62 197.0 COG3797@1|root,COG3797@2|Bacteria,1VDUT@1239|Firmicutes,4HMM0@91061|Bacilli,27GQ9@186828|Carnobacteriaceae 91061|Bacilli S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 gnl|extdb|FAM24227-i1-1.1_000850 1121024.AUCD01000016_gene310 1.7e-126 369.0 COG0451@1|root,COG0451@2|Bacteria,1TR3K@1239|Firmicutes,4HD3P@91061|Bacilli,27H41@186828|Carnobacteriaceae 91061|Bacilli GM Dehydratase - - - - - - - - - - - - Epimerase gnl|extdb|FAM24227-i1-1.1_000851 1140001.I571_02512 1.16e-49 160.0 COG1359@1|root,COG1359@2|Bacteria,1V8JS@1239|Firmicutes,4HKAP@91061|Bacilli,4B3DQ@81852|Enterococcaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM gnl|extdb|FAM24227-i1-1.1_000852 1175629.AJTG01000005_gene729 2.58e-103 308.0 COG3705@1|root,COG3705@2|Bacteria,1V3AB@1239|Firmicutes,4HGHG@91061|Bacilli 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - - - - - - - - - - tRNA-synt_His gnl|extdb|FAM24227-i1-1.1_000853 655812.HMPREF0061_0725 1.71e-95 283.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His gnl|extdb|FAM24227-i1-1.1_000855 655812.HMPREF0061_0723 1.04e-117 350.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_000856 655812.HMPREF0061_0722 9.49e-96 283.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD gnl|extdb|FAM24227-i1-1.1_000857 655812.HMPREF0061_0721 1.77e-112 328.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli 91061|Bacilli E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth gnl|extdb|FAM24227-i1-1.1_000858 655812.HMPREF0061_0720 1.44e-115 338.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth gnl|extdb|FAM24227-i1-1.1_000859 1175629.AJTG01000005_gene722 5.27e-96 285.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH gnl|extdb|FAM24227-i1-1.1_000860 565653.EGBG_02642 4.52e-73 231.0 COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HGYX@91061|Bacilli,4B6FW@81852|Enterococcaceae 91061|Bacilli E Histidinol phosphatase and related hydrolases of the PHP family hisJ - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - - gnl|extdb|FAM24227-i1-1.1_000861 1122129.AUEF01000008_gene2040 9.61e-152 441.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,4GYMV@90964|Staphylococcaceae 91061|Bacilli E acetylornithine aminotransferase argD - 2.6.1.11,2.6.1.13,2.6.1.17 ko:K00819,ko:K00821 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 gnl|extdb|FAM24227-i1-1.1_000862 1122129.AUEF01000008_gene2039 6.04e-109 325.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,4GX25@90964|Staphylococcaceae 91061|Bacilli E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase gnl|extdb|FAM24227-i1-1.1_000863 1122129.AUEF01000008_gene2038 1.22e-135 401.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,4GY9F@90964|Staphylococcaceae 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ gnl|extdb|FAM24227-i1-1.1_000864 655812.HMPREF0061_0164 3.17e-133 390.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC gnl|extdb|FAM24227-i1-1.1_000865 883103.HMPREF9703_00145 5.85e-173 490.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,27FUB@186828|Carnobacteriaceae 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N gnl|extdb|FAM24227-i1-1.1_000866 1175629.AJTG01000022_gene1730 3.57e-69 214.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,27E0E@186827|Aerococcaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran gnl|extdb|FAM24227-i1-1.1_000867 655812.HMPREF0061_1144 4.07e-154 439.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,27EH7@186827|Aerococcaceae 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N gnl|extdb|FAM24227-i1-1.1_000868 1408438.JADD01000002_gene337 2.94e-206 582.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,27DMY@186827|Aerococcaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 gnl|extdb|FAM24227-i1-1.1_000869 1175629.AJTG01000022_gene1727 9.67e-145 416.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,27EIQ@186827|Aerococcaceae 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh gnl|extdb|FAM24227-i1-1.1_000870 1196322.A370_00795 1.04e-43 145.0 COG3695@1|root,COG3695@2|Bacteria,1VC8H@1239|Firmicutes,24JGN@186801|Clostridia,36JM6@31979|Clostridiaceae 186801|Clostridia L 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 gnl|extdb|FAM24227-i1-1.1_000871 1175629.AJTG01000017_gene1699 3.25e-120 353.0 COG3173@1|root,COG3173@2|Bacteria,1TPYB@1239|Firmicutes,4HBYQ@91061|Bacilli 91061|Bacilli S Phosphotransferase enzyme family ycbJ - - ko:K06979 - M00760 - - br01600,ko00000,ko00002,ko01504 - - - APH gnl|extdb|FAM24227-i1-1.1_000872 1121024.AUCD01000024_gene764 1.55e-17 77.8 COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,4HNXQ@91061|Bacilli,27GY4@186828|Carnobacteriaceae 91061|Bacilli S Protein of unknown function (DUF1294) ysdA - - - - - - - - - - - DUF1294 gnl|extdb|FAM24227-i1-1.1_000873 1121024.AUCD01000009_gene2047 2.14e-98 293.0 COG1842@1|root,COG1842@2|Bacteria,1UYNB@1239|Firmicutes,4HAMR@91061|Bacilli,27G1I@186828|Carnobacteriaceae 91061|Bacilli KT PspA/IM30 family pspA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03969 - - - - ko00000 - - - PspA_IM30 gnl|extdb|FAM24227-i1-1.1_000875 525379.HMPREF0819_1008 2.08e-162 458.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli 91061|Bacilli L exodeoxyribonuclease III xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos gnl|extdb|FAM24227-i1-1.1_000876 655812.HMPREF0061_1299 3.5e-63 208.0 COG1876@1|root,COG1876@2|Bacteria,1V6U8@1239|Firmicutes,4HJCV@91061|Bacilli,27E12@186827|Aerococcaceae 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase dacB - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY gnl|extdb|FAM24227-i1-1.1_000877 698758.AXY_13800 6.96e-44 145.0 COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli 91061|Bacilli P Alkylphosphonate utilization operon protein PhnA phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon gnl|extdb|FAM24227-i1-1.1_000878 1408438.JADD01000017_gene1438 3.8e-50 176.0 COG2367@1|root,COG2367@2|Bacteria,1V9PM@1239|Firmicutes,4I6BS@91061|Bacilli,27E0P@186827|Aerococcaceae 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 gnl|extdb|FAM24227-i1-1.1_000880 208596.CAR_c23340 1.7e-116 337.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,27G65@186828|Carnobacteriaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 gnl|extdb|FAM24227-i1-1.1_000881 1408438.JADD01000010_gene1923 2.01e-234 672.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,27EEA@186827|Aerococcaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind gnl|extdb|FAM24227-i1-1.1_000882 1500281.JQKZ01000022_gene860 0.000107 45.1 COG0604@1|root,COG0604@2|Bacteria,4NJ5X@976|Bacteroidetes,1IIKA@117743|Flavobacteriia 976|Bacteroidetes C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 gnl|extdb|FAM24227-i1-1.1_000883 1123359.AUIQ01000016_gene686 2.08e-132 380.0 COG1878@1|root,COG1878@2|Bacteria,1TRBQ@1239|Firmicutes,4HCAB@91061|Bacilli,4B0JU@81852|Enterococcaceae 91061|Bacilli S Putative cyclase XK27_00940 - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase gnl|extdb|FAM24227-i1-1.1_000884 596330.HMPREF0628_1577 3.33e-37 128.0 COG3323@1|root,COG3323@2|Bacteria,1VG09@1239|Firmicutes,24TV5@186801|Clostridia,22IVZ@1570339|Peptoniphilaceae 186801|Clostridia L Protein of unknown function (DUF1653) - - - - - - - - - - - - CutA1 gnl|extdb|FAM24227-i1-1.1_000885 1167632.AJTR01000102_gene1969 5.2e-77 232.0 28NR0@1|root,2ZBQD@2|Bacteria,1V1Z5@1239|Firmicutes,4HGAG@91061|Bacilli,4GZ16@90964|Staphylococcaceae 91061|Bacilli S Nucleoside 2-deoxyribosyltransferase YtoQ ytoQ - - - - - - - - - - - Nuc_deoxyri_tr3 gnl|extdb|FAM24227-i1-1.1_000886 1449338.JQLU01000005_gene2861 1.63e-65 211.0 COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,27H4F@186828|Carnobacteriaceae 91061|Bacilli K helix_turn_helix isocitrate lyase regulation - - - ko:K19333 - - - - ko00000,ko03000 - - - HTH_IclR,IclR gnl|extdb|FAM24227-i1-1.1_000887 883113.HMPREF9708_00953 6.06e-74 244.0 COG3247@1|root,COG3247@2|Bacteria,1UYYV@1239|Firmicutes,4HIX0@91061|Bacilli,27E4S@186827|Aerococcaceae 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - DUF308 gnl|extdb|FAM24227-i1-1.1_000888 1449342.JQMR01000005_gene2451 1.04e-34 131.0 COG5527@1|root,COG5527@2|Bacteria 2|Bacteria L Initiator Replication protein - - - - - - - - - - - - NERD,Rep_3 gnl|extdb|FAM24227-i1-1.1_000889 1449335.JQLG01000005_gene2410 6.72e-08 53.5 2BXYH@1|root,32XYH@2|Bacteria,1VB6X@1239|Firmicutes,4HKP5@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000891 1347087.CBYO010000020_gene3035 6.87e-68 213.0 COG2019@1|root,COG2019@2|Bacteria,1V6Q3@1239|Firmicutes,4HK46@91061|Bacilli 91061|Bacilli F adenylate kinase activity - - - - - - - - - - - - AAA_18 gnl|extdb|FAM24227-i1-1.1_000893 1121024.AUCD01000009_gene2028 3.5e-123 353.0 COG3275@1|root,COG3275@2|Bacteria,1V65C@1239|Firmicutes,4HF9E@91061|Bacilli,27GSP@186828|Carnobacteriaceae 91061|Bacilli T Psort location CytoplasmicMembrane, score - - - ko:K16923 - M00582 - - ko00000,ko00002,ko02000 3.A.1.28 - - ECF_trnsprt gnl|extdb|FAM24227-i1-1.1_000894 1121024.AUCD01000009_gene2029 1.62e-119 348.0 COG0619@1|root,COG0619@2|Bacteria,1UYQQ@1239|Firmicutes,4HFDP@91061|Bacilli,27GV3@186828|Carnobacteriaceae 91061|Bacilli P Cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ gnl|extdb|FAM24227-i1-1.1_000895 1121024.AUCD01000009_gene2030 6.9e-152 432.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HD3G@91061|Bacilli,27GBM@186828|Carnobacteriaceae 91061|Bacilli P ATPases associated with a variety of cellular activities - - - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000896 1121024.AUCD01000009_gene2031 5.74e-123 358.0 COG1122@1|root,COG1122@2|Bacteria,1TQAV@1239|Firmicutes,4HCMA@91061|Bacilli,27GDQ@186828|Carnobacteriaceae 91061|Bacilli P ATPases associated with a variety of cellular activities - - - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000898 1216932.CM240_2217 1.43e-67 211.0 COG1670@1|root,COG1670@2|Bacteria,1V2FI@1239|Firmicutes,25B0M@186801|Clostridia,36WDN@31979|Clostridiaceae 186801|Clostridia J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 gnl|extdb|FAM24227-i1-1.1_000900 999415.HMPREF9943_01330 9.01e-56 177.0 COG0105@1|root,COG0105@2|Bacteria,1TTIT@1239|Firmicutes,3VQR3@526524|Erysipelotrichia 526524|Erysipelotrichia F Nucleoside diphosphate kinase ndk - - - - - - - - - - - NDK gnl|extdb|FAM24227-i1-1.1_000901 1121024.AUCD01000007_gene1976 3.7e-70 218.0 COG2897@1|root,COG2897@2|Bacteria 2|Bacteria P thiosulfate sulfurtransferase activity - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese gnl|extdb|FAM24227-i1-1.1_000902 1408438.JADD01000012_gene1672 0.0 899.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli 91061|Bacilli P Belongs to the alkaline phosphatase family - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase,Cu_amine_oxidN1 gnl|extdb|FAM24227-i1-1.1_000908 1121871.AUAT01000006_gene1516 7.53e-117 338.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,27DHN@186827|Aerococcaceae 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 gnl|extdb|FAM24227-i1-1.1_000909 592010.GCWU000182_000708 4.57e-114 335.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,27DWV@186827|Aerococcaceae 91061|Bacilli M Phosphotransferase enzyme family ytmP - - - - - - - - - - - APH gnl|extdb|FAM24227-i1-1.1_000910 1121871.AUAT01000006_gene1514 1.55e-36 127.0 COG5584@1|root,COG5584@2|Bacteria,1TX5V@1239|Firmicutes,4I627@91061|Bacilli,27E5S@186827|Aerococcaceae 91061|Bacilli S Small secreted protein - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000854 655812.HMPREF0061_0724 1.75e-171 492.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14140 Histidinol_dh gnl|extdb|FAM24227-i1-1.1_000874 1121024.AUCD01000009_gene2046 4.82e-94 287.0 COG1512@1|root,COG1512@2|Bacteria,1UZ8H@1239|Firmicutes,4HCBB@91061|Bacilli,27G3T@186828|Carnobacteriaceae 91061|Bacilli S COG1512 Beta-propeller domains of methanol dehydrogenase type - - - - - - - - - - - - TPM_phosphatase gnl|extdb|FAM24227-i1-1.1_000879 411464.DESPIG_03110 3.38e-90 276.0 COG0697@1|root,COG0697@2|Bacteria,1MXMS@1224|Proteobacteria,42W2P@68525|delta/epsilon subdivisions,2X5B4@28221|Deltaproteobacteria 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA gnl|extdb|FAM24227-i1-1.1_000911 1499680.CCFE01000018_gene1438 2.1e-16 83.2 COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,4HCC3@91061|Bacilli,1ZCQ2@1386|Bacillus 91061|Bacilli NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases comC - 3.4.23.43 ko:K02236,ko:K02654 - M00331,M00429 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 gnl|extdb|FAM24227-i1-1.1_000912 908337.HMPREF9257_0786 0.0 2071.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,27DF2@186827|Aerococcaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 gnl|extdb|FAM24227-i1-1.1_000913 883112.HMPREF9707_00804 0.0 2081.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,27DQE@186827|Aerococcaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 gnl|extdb|FAM24227-i1-1.1_000914 908337.HMPREF9257_0789 3.81e-69 216.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HK59@91061|Bacilli,27F4M@186827|Aerococcaceae 91061|Bacilli J Nodulation protein S (NodS) XK27_09540 - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS gnl|extdb|FAM24227-i1-1.1_000915 883112.HMPREF9707_00823 5.42e-96 291.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,27DZA@186827|Aerococcaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ycsE - - - - - - - - - - - Hydrolase_3 gnl|extdb|FAM24227-i1-1.1_000916 1449337.JQLL01000001_gene1131 1.45e-44 157.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,27G6Y@186828|Carnobacteriaceae 91061|Bacilli S Alpha/beta hydrolase family est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 gnl|extdb|FAM24227-i1-1.1_000917 1304866.K413DRAFT_0637 7.83e-109 323.0 COG0596@1|root,COG0596@2|Bacteria,1TSPF@1239|Firmicutes,24AD1@186801|Clostridia,36FJN@31979|Clostridiaceae 186801|Clostridia S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 gnl|extdb|FAM24227-i1-1.1_000919 1123230.ARQJ01000022_gene2108 1.89e-75 237.0 COG3971@1|root,COG3971@2|Bacteria,1TQVG@1239|Firmicutes,4HBMC@91061|Bacilli,4GYBA@90964|Staphylococcaceae 91061|Bacilli Q hydratase - - - - - - - - - - - - FAA_hydrolase gnl|extdb|FAM24227-i1-1.1_000920 1235279.C772_01746 3.58e-155 445.0 COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,4HAXZ@91061|Bacilli,26DVG@186818|Planococcaceae 91061|Bacilli H Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds dmpG - 4.1.3.39 ko:K01666 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R00750 RC00307,RC00371 br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like gnl|extdb|FAM24227-i1-1.1_000921 1117379.BABA_14522 1.9e-129 377.0 COG4569@1|root,COG4569@2|Bacteria,1TQJS@1239|Firmicutes,4HCRZ@91061|Bacilli,1ZEE6@1386|Bacillus 91061|Bacilli Q Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds mhpF - 1.2.1.10 ko:K04073 ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220 M00545,M00569 R00228,R01172 RC00004,RC00184,RC01195 br01602,ko00000,ko00001,ko00002,ko01000 - - - AcetDehyd-dimer,Semialdhyde_dh gnl|extdb|FAM24227-i1-1.1_000922 1123230.ARQJ01000022_gene2107 1.42e-95 288.0 COG3971@1|root,COG3971@2|Bacteria,1TQVG@1239|Firmicutes,4HBMC@91061|Bacilli,4GYBA@90964|Staphylococcaceae 91061|Bacilli Q hydratase - - 4.2.1.80 ko:K02554 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R02601,R04781 RC00750,RC01213 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase gnl|extdb|FAM24227-i1-1.1_000923 333138.LQ50_25045 3.21e-66 213.0 COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,1ZDR0@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR gnl|extdb|FAM24227-i1-1.1_000924 883112.HMPREF9707_00832 2.87e-59 185.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,27E02@186827|Aerococcaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N gnl|extdb|FAM24227-i1-1.1_000925 883112.HMPREF9707_00833 1.21e-79 241.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,27DZF@186827|Aerococcaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 gnl|extdb|FAM24227-i1-1.1_000926 883112.HMPREF9707_00834 2.41e-141 401.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,27DG7@186827|Aerococcaceae 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 gnl|extdb|FAM24227-i1-1.1_000927 883112.HMPREF9707_00835 6.82e-84 249.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,27DYK@186827|Aerococcaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N gnl|extdb|FAM24227-i1-1.1_000928 1198676.SMUGS5_07585 9.58e-68 223.0 COG1073@1|root,COG1073@2|Bacteria,1V38K@1239|Firmicutes,4HF0V@91061|Bacilli 91061|Bacilli S BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - BAAT_C,Bile_Hydr_Trans gnl|extdb|FAM24227-i1-1.1_000929 1121871.AUAT01000021_gene61 5.99e-68 218.0 COG1030@1|root,COG1030@2|Bacteria,1V6UR@1239|Firmicutes,4HJIN@91061|Bacilli,27E9F@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - TspO_MBR gnl|extdb|FAM24227-i1-1.1_000930 883112.HMPREF9707_00837 2.18e-92 273.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,27DU6@186827|Aerococcaceae 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG gnl|extdb|FAM24227-i1-1.1_000931 883110.HMPREF9260_01574 2.16e-17 74.7 2EG1I@1|root,339TI@2|Bacteria,1U4G2@1239|Firmicutes,4I62B@91061|Bacilli,27E8K@186827|Aerococcaceae 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - - - - - - - - - - SecE gnl|extdb|FAM24227-i1-1.1_000932 883112.HMPREF9707_00839 1.53e-25 94.7 COG0267@1|root,COG0267@2|Bacteria,1VFTQ@1239|Firmicutes,4HR5Q@91061|Bacilli,27EZ5@186827|Aerococcaceae 91061|Bacilli J Ribosomal protein L33 rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 gnl|extdb|FAM24227-i1-1.1_000933 1449336.JQLO01000001_gene1975 1.13e-23 100.0 COG1595@1|root,COG1595@2|Bacteria,1VG7U@1239|Firmicutes,4HNKD@91061|Bacilli,27GS8@186828|Carnobacteriaceae 91061|Bacilli K Sigma-70 region 2 comX - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 gnl|extdb|FAM24227-i1-1.1_000934 883112.HMPREF9707_00843 6.18e-87 260.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,27DZS@186827|Aerococcaceae 91061|Bacilli S YacP-like NYN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP gnl|extdb|FAM24227-i1-1.1_000935 883112.HMPREF9707_00844 7.11e-123 357.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,27DDA@186827|Aerococcaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind gnl|extdb|FAM24227-i1-1.1_000936 1408438.JADD01000030_gene1257 2.06e-55 176.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,27E2C@186827|Aerococcaceae 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 gnl|extdb|FAM24227-i1-1.1_000937 883112.HMPREF9707_00846 1.03e-238 668.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,27DGJ@186827|Aerococcaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g gnl|extdb|FAM24227-i1-1.1_000938 866775.HMPREF9243_0124 7.97e-101 300.0 COG1878@1|root,COG1878@2|Bacteria,1TRBQ@1239|Firmicutes,4HCAB@91061|Bacilli,27EN8@186827|Aerococcaceae 91061|Bacilli S Putative cyclase XK27_00940 - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase gnl|extdb|FAM24227-i1-1.1_000939 1400520.LFAB_11975 5.42e-180 512.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F49P@33958|Lactobacillaceae 91061|Bacilli E methionine synthase, vitamin-B12 independent - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 gnl|extdb|FAM24227-i1-1.1_000940 1408438.JADD01000030_gene1259 7.42e-293 806.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,27DKB@186827|Aerococcaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c gnl|extdb|FAM24227-i1-1.1_000941 592010.GCWU000182_001959 7.78e-140 409.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,27DRC@186827|Aerococcaceae 91061|Bacilli S PIN domain protein yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM gnl|extdb|FAM24227-i1-1.1_000942 1408438.JADD01000030_gene1261 1.98e-251 699.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,27DI6@186827|Aerococcaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI gnl|extdb|FAM24227-i1-1.1_000943 592010.GCWU000182_001961 1.9e-80 244.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,27DUD@186827|Aerococcaceae 91061|Bacilli F dUTPase dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase gnl|extdb|FAM24227-i1-1.1_000944 1123308.KB904538_gene234 6.69e-255 710.0 COG0366@1|root,COG0366@2|Bacteria,1TRKZ@1239|Firmicutes,4HC8C@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyL - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF1939 gnl|extdb|FAM24227-i1-1.1_000946 411474.COPEUT_00517 7.76e-42 142.0 COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score - - - ko:K06934 - - - - ko00000 - - - DUF296 gnl|extdb|FAM24227-i1-1.1_000948 883103.HMPREF9703_00702 9.17e-48 160.0 COG2963@1|root,COG2963@2|Bacteria,1V35U@1239|Firmicutes,4HHRN@91061|Bacilli,27GJT@186828|Carnobacteriaceae 91061|Bacilli L Helix-turn-helix domain - - - ko:K07483,ko:K07497 - - - - ko00000 - - - HTH_28,HTH_Tnp_1 gnl|extdb|FAM24227-i1-1.1_000949 558169.AGAV01000014_gene1731 1.03e-124 366.0 COG0604@1|root,COG0604@2|Bacteria,1TT3B@1239|Firmicutes,4HCBV@91061|Bacilli 91061|Bacilli C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N gnl|extdb|FAM24227-i1-1.1_000950 1298920.KI911353_gene1964 5.62e-117 346.0 COG2378@1|root,COG2378@2|Bacteria,1TPS2@1239|Firmicutes,25C7J@186801|Clostridia 186801|Clostridia K WYL domain - - - - - - - - - - - - HTH_11,WYL gnl|extdb|FAM24227-i1-1.1_000951 1347392.CCEZ01000004_gene698 1.54e-07 52.4 2EIWS@1|root,33CN3@2|Bacteria,1VMC7@1239|Firmicutes,24R1C@186801|Clostridia,36NA4@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000952 1347392.CCEZ01000004_gene697 2.16e-43 154.0 COG4200@1|root,COG4200@2|Bacteria,1TRGZ@1239|Firmicutes,2498Y@186801|Clostridia,36DMK@31979|Clostridiaceae 186801|Clostridia S ABC-2 family transporter protein - - - ko:K20461 ko02010,map02010 M00813 - - ko00000,ko00001,ko00002,ko02000 3.A.1.124.3,3.A.1.124.4,3.A.1.124.5 - - ABC2_membrane_4 gnl|extdb|FAM24227-i1-1.1_000953 1462527.CCDM010000009_gene355 7.78e-15 79.0 COG4200@1|root,COG4200@2|Bacteria,1TP4G@1239|Firmicutes 1239|Firmicutes S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - ABC2_membrane_4 gnl|extdb|FAM24227-i1-1.1_000954 658655.HMPREF0988_01670 1.9e-116 340.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,27K0T@186928|unclassified Lachnospiraceae 186801|Clostridia V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990,ko:K20459 ko02010,map02010 M00254,M00813 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000955 411468.CLOSCI_02319 1.27e-70 223.0 COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,222UJ@1506553|Lachnoclostridium 186801|Clostridia K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C gnl|extdb|FAM24227-i1-1.1_000956 1235799.C818_03701 4.81e-97 306.0 COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,27IC6@186928|unclassified Lachnospiraceae 186801|Clostridia T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA gnl|extdb|FAM24227-i1-1.1_000957 1266845.Q783_07680 1.07e-170 486.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HBDF@91061|Bacilli,27I06@186828|Carnobacteriaceae 91061|Bacilli L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_000958 1229520.ADIAL_0477 2.54e-102 306.0 COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,4HGS5@91061|Bacilli,27HVI@186828|Carnobacteriaceae 91061|Bacilli L Endonuclease/Exonuclease/phosphatase family rgfB - 3.1.3.90 ko:K06896 ko00500,map00500 - R10486 RC00017 ko00000,ko00001,ko01000 - - - Exo_endo_phos gnl|extdb|FAM24227-i1-1.1_000959 1140001.I571_00304 0.0 1004.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,4AZKN@81852|Enterococcaceae 91061|Bacilli G phosphotransferase system, EIIB ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_000960 1139996.OMQ_01601 3.18e-132 389.0 COG3385@1|root,COG3385@2|Bacteria,1UZPH@1239|Firmicutes,4HAJR@91061|Bacilli,4B270@81852|Enterococcaceae 91061|Bacilli L Transposase DDE domain - - - ko:K07495 - - - - ko00000 - - - DDE_Tnp_1,DUF4372 gnl|extdb|FAM24227-i1-1.1_000961 1499685.CCFJ01000038_gene1236 1.88e-55 182.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HBHG@91061|Bacilli,1ZQDY@1386|Bacillus 91061|Bacilli L HTH-like domain - - - - - - - - - - - - HTH_21,rve,rve_2 gnl|extdb|FAM24227-i1-1.1_000962 1121105.ATXL01000038_gene534 1.5e-21 87.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli,4B3J9@81852|Enterococcaceae 91061|Bacilli L Integrase core domain - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_000918 1134413.ANNK01000091_gene53 1.89e-134 393.0 COG0346@1|root,COG0346@2|Bacteria,1U664@1239|Firmicutes,4IS09@91061|Bacilli 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_000945 717605.Theco_0085 9.37e-86 255.0 COG0590@1|root,COG0590@2|Bacteria,1V1K9@1239|Firmicutes,4HG1S@91061|Bacilli,26XKV@186822|Paenibacillaceae 91061|Bacilli FJ MafB19-like deaminase guaD - - - - - - - - - - - MafB19-deam,dCMP_cyt_deam_1 gnl|extdb|FAM24227-i1-1.1_000947 1499685.CCFJ01000038_gene1236 8.99e-127 369.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HBHG@91061|Bacilli,1ZQDY@1386|Bacillus 91061|Bacilli L HTH-like domain - - - - - - - - - - - - HTH_21,rve,rve_2 gnl|extdb|FAM24227-i1-1.1_000963 883110.HMPREF9260_01797 3.8e-83 262.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,27EKW@186827|Aerococcaceae 91061|Bacilli M Glycosyl transferase family 4 tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 gnl|extdb|FAM24227-i1-1.1_000964 1408438.JADD01000013_gene1688 1.12e-129 375.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,27DEN@186827|Aerococcaceae 91061|Bacilli H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase gnl|extdb|FAM24227-i1-1.1_000965 1408438.JADD01000013_gene1687 2.5e-293 808.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,27EBX@186827|Aerococcaceae 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase gnl|extdb|FAM24227-i1-1.1_000966 208596.CAR_c23230 3.23e-94 288.0 28H7K@1|root,2Z7JT@2|Bacteria,1UPH1@1239|Firmicutes,4HE88@91061|Bacilli,27GVB@186828|Carnobacteriaceae 91061|Bacilli P 2-keto-3-deoxygluconate permease - - - ko:K02526 - - - - ko00000,ko02000 2.A.10.1 - - KdgT gnl|extdb|FAM24227-i1-1.1_000968 1408438.JADD01000009_gene1763 5.71e-27 117.0 2F92J@1|root,341E8@2|Bacteria,1VX7X@1239|Firmicutes,4HWWX@91061|Bacilli,27EUT@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000969 908337.HMPREF9257_0200 3.44e-228 640.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB15@91061|Bacilli,27DP3@186827|Aerococcaceae 91061|Bacilli M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase tuaA - - - - - - - - - - - Bac_transf,CoA_binding_3 gnl|extdb|FAM24227-i1-1.1_000970 1408438.JADD01000035_gene444 4.88e-189 530.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,27DNG@186827|Aerococcaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N gnl|extdb|FAM24227-i1-1.1_000971 1449336.JQLO01000001_gene2414 1.35e-193 552.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,27F9R@186828|Carnobacteriaceae 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase gnl|extdb|FAM24227-i1-1.1_000972 592010.GCWU000182_000670 5.68e-100 301.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,27DW6@186827|Aerococcaceae 91061|Bacilli F Pur operon repressor PurR purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N gnl|extdb|FAM24227-i1-1.1_000973 1449342.JQMR01000001_gene1544 5.04e-10 60.8 2BYV2@1|root,33ICM@2|Bacteria,1VMF3@1239|Firmicutes,4I555@91061|Bacilli,27HRF@186828|Carnobacteriaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000974 1139996.OMQ_02090 1.11e-175 501.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,4AZ71@81852|Enterococcaceae 91061|Bacilli G Mannitol dehydrogenase C-terminal domain mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C gnl|extdb|FAM24227-i1-1.1_000975 1408438.JADD01000035_gene448 2.11e-74 225.0 COG4668@1|root,COG4668@2|Bacteria,1V77P@1239|Firmicutes,4HIM2@91061|Bacilli,27EQM@186827|Aerococcaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 mtlF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02798 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2 gnl|extdb|FAM24227-i1-1.1_000976 1123359.AUIQ01000006_gene1404 4.34e-175 522.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,4B1DF@81852|Enterococcaceae 91061|Bacilli K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB gnl|extdb|FAM24227-i1-1.1_000977 1408438.JADD01000035_gene450 1.59e-249 705.0 COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,27EJ1@186827|Aerococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIC,PTS_IIB gnl|extdb|FAM24227-i1-1.1_000978 1408438.JADD01000035_gene451 1.11e-118 347.0 COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli,27DVK@186827|Aerococcaceae 91061|Bacilli P ABC 3 transport family protein adcB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 gnl|extdb|FAM24227-i1-1.1_000979 592010.GCWU000182_000672 8.65e-126 362.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,27DJ9@186827|Aerococcaceae 91061|Bacilli P ABC transporter, ATP-binding protein adcC - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran gnl|extdb|FAM24227-i1-1.1_000980 592010.GCWU000182_000673 1.46e-104 315.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,27DWB@186827|Aerococcaceae 91061|Bacilli P ABC transporter, substrate-binding protein psaA3 - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA gnl|extdb|FAM24227-i1-1.1_000981 1408438.JADD01000043_gene1345 1.34e-99 302.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli,27EA3@186827|Aerococcaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system potA3 - - ko:K01990,ko:K19309 ko02010,map02010 M00254,M00747 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.131.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000982 318464.IO99_02215 8.17e-07 57.0 COG1277@1|root,COG1277@2|Bacteria,1V8KD@1239|Firmicutes,25F20@186801|Clostridia,36UVD@31979|Clostridiaceae 186801|Clostridia S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_4 gnl|extdb|FAM24227-i1-1.1_000985 1408438.JADD01000035_gene455 4.57e-102 301.0 COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,4HB8Z@91061|Bacilli,27DTR@186827|Aerococcaceae 91061|Bacilli S neutral zinc metallopeptidase yugP - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 gnl|extdb|FAM24227-i1-1.1_000986 883112.HMPREF9707_00041 6.87e-208 586.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,27DHK@186827|Aerococcaceae 91061|Bacilli F Permease family pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease gnl|extdb|FAM24227-i1-1.1_000987 1408438.JADD01000035_gene456 2.54e-133 384.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,27DN3@186827|Aerococcaceae 91061|Bacilli S ABC transporter - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran gnl|extdb|FAM24227-i1-1.1_000988 1408438.JADD01000035_gene457 1.74e-139 403.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,27EFG@186827|Aerococcaceae 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family WQ51_06230 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 gnl|extdb|FAM24227-i1-1.1_000989 1408438.JADD01000035_gene458 5.85e-113 337.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,27EMG@186827|Aerococcaceae 91061|Bacilli S ABC transporter substrate binding protein XK27_00670 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind gnl|extdb|FAM24227-i1-1.1_000990 1408438.JADD01000035_gene458 1.35e-150 432.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,27EMG@186827|Aerococcaceae 91061|Bacilli S ABC transporter substrate binding protein XK27_00670 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind gnl|extdb|FAM24227-i1-1.1_000991 908337.HMPREF9257_0214 3e-136 397.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,27DUP@186827|Aerococcaceae 91061|Bacilli S ABC transporter substrate binding protein XK27_00670 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind gnl|extdb|FAM24227-i1-1.1_000993 592010.GCWU000182_001599 1.25e-73 229.0 COG2949@1|root,COG2949@2|Bacteria,1V1FP@1239|Firmicutes,4HJYA@91061|Bacilli,27EP7@186827|Aerococcaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 gnl|extdb|FAM24227-i1-1.1_000994 1408438.JADD01000014_gene600 1.5e-179 508.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,27DNC@186827|Aerococcaceae 91061|Bacilli E Amino-transferase class IV ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 gnl|extdb|FAM24227-i1-1.1_000995 883113.HMPREF9708_00557 9.63e-25 103.0 2FID4@1|root,34A5C@2|Bacteria,1UHKM@1239|Firmicutes,4IS3M@91061|Bacilli,27F66@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_000996 592010.GCWU000182_000676 5.09e-118 358.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,27DUF@186827|Aerococcaceae 91061|Bacilli K RNA polymerase sigma-54 factor rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD gnl|extdb|FAM24227-i1-1.1_000997 883112.HMPREF9707_00039 2.84e-102 319.0 COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,27EPV@186827|Aerococcaceae 91061|Bacilli G Polysaccharide deacetylase cda1 - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - CBM_6,Polysacc_deac_1 gnl|extdb|FAM24227-i1-1.1_000998 883112.HMPREF9707_00038 2.39e-126 371.0 COG2321@1|root,COG2321@2|Bacteria,1TQKF@1239|Firmicutes,4HB7I@91061|Bacilli 91061|Bacilli S metalloprotease XK27_03670 - - ko:K07054 - - - - ko00000 - - - Zn_peptidase gnl|extdb|FAM24227-i1-1.1_000999 883112.HMPREF9707_00037 4.57e-227 642.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,27DMI@186827|Aerococcaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N gnl|extdb|FAM24227-i1-1.1_001000 1139996.OMQ_00204 1.32e-52 170.0 COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli,4B2KG@81852|Enterococcaceae 91061|Bacilli S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 gnl|extdb|FAM24227-i1-1.1_001002 1408438.JADD01000029_gene1354 1.35e-36 127.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HJ09@91061|Bacilli 91061|Bacilli K transcriptional - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 gnl|extdb|FAM24227-i1-1.1_001003 883112.HMPREF9707_00036 1.06e-68 219.0 COG1266@1|root,COG1266@2|Bacteria,1VEE2@1239|Firmicutes,4HP4A@91061|Bacilli,27E6C@186827|Aerococcaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi gnl|extdb|FAM24227-i1-1.1_001004 1408438.JADD01000029_gene1355 5.56e-21 100.0 2DCC3@1|root,2ZDMP@2|Bacteria,1W37R@1239|Firmicutes,4HZJN@91061|Bacilli,27F09@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001005 883112.HMPREF9707_00034 4.51e-56 186.0 COG0546@1|root,COG0546@2|Bacteria,1V92U@1239|Firmicutes,4HJ52@91061|Bacilli,27ERP@186827|Aerococcaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 gnl|extdb|FAM24227-i1-1.1_001007 883112.HMPREF9707_00032 4.5e-101 300.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,27DN0@186827|Aerococcaceae 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso gnl|extdb|FAM24227-i1-1.1_001008 421052.F945_00341 3.55e-17 87.0 COG4977@1|root,COG4977@2|Bacteria,1MXZQ@1224|Proteobacteria,1RQM6@1236|Gammaproteobacteria,3NJ59@468|Moraxellaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein tetD - - ko:K07506 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18,HTH_AraC gnl|extdb|FAM24227-i1-1.1_001009 883113.HMPREF9708_00744 8.56e-113 332.0 COG2207@1|root,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,4HCIE@91061|Bacilli,27DBY@186827|Aerococcaceae 91061|Bacilli K transcriptional regulator (AraC family) - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC gnl|extdb|FAM24227-i1-1.1_001010 754027.HMPREF9554_01453 0.0 1125.0 COG0474@1|root,COG0474@2|Bacteria,2J60N@203691|Spirochaetes 203691|Spirochaetes P Cation transporter/ATPase, N-terminus mgtB - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase gnl|extdb|FAM24227-i1-1.1_001011 883113.HMPREF9708_00744 3.61e-101 303.0 COG2207@1|root,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,4HCIE@91061|Bacilli,27DBY@186827|Aerococcaceae 91061|Bacilli K transcriptional regulator (AraC family) - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC gnl|extdb|FAM24227-i1-1.1_001012 1408438.JADD01000008_gene1523 3.49e-37 126.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_000983 1214166.ALLG01000009_gene515 6.42e-39 134.0 COG2832@1|root,COG2832@2|Bacteria,1VC3R@1239|Firmicutes,4HMWE@91061|Bacilli,1WTKP@1307|Streptococcus suis 91061|Bacilli S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 gnl|extdb|FAM24227-i1-1.1_000984 1408438.JADD01000035_gene454 5.16e-171 489.0 COG3596@1|root,COG3597@1|root,COG3596@2|Bacteria,COG3597@2|Bacteria,1TSZW@1239|Firmicutes,4HAIB@91061|Bacilli,27DTC@186827|Aerococcaceae 91061|Bacilli S Dynamin family - - - - - - - - - - - - DUF697,MMR_HSR1 gnl|extdb|FAM24227-i1-1.1_000992 1336234.JAGN01000039_gene395 1.58e-117 348.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,27H2X@186828|Carnobacteriaceae 91061|Bacilli CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ddh - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C gnl|extdb|FAM24227-i1-1.1_001001 1121871.AUAT01000028_gene1229 3.97e-111 327.0 COG1304@1|root,COG1304@2|Bacteria,1TUS7@1239|Firmicutes,4IT5C@91061|Bacilli,27F6W@186827|Aerococcaceae 91061|Bacilli C FMN binding - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001013 883112.HMPREF9707_00331 6.07e-152 430.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,27DKF@186827|Aerococcaceae 91061|Bacilli E Metallopeptidase family M24 map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 gnl|extdb|FAM24227-i1-1.1_001014 908337.HMPREF9257_1457 3.08e-35 133.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli,27E7E@186827|Aerococcaceae 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE gnl|extdb|FAM24227-i1-1.1_001015 1121871.AUAT01000002_gene1452 2.38e-15 71.2 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,27E5K@186827|Aerococcaceae 91061|Bacilli S Transglycosylase associated protein ydaS - - - - - - - - - - - Transgly_assoc gnl|extdb|FAM24227-i1-1.1_001016 1123312.KB904584_gene658 8.38e-126 369.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli 91061|Bacilli V proteins, homologs of microcin C7 resistance protein MccF - - - - - - - - - - - - Peptidase_S66 gnl|extdb|FAM24227-i1-1.1_001017 1408438.JADD01000017_gene1442 1.07e-202 575.0 COG1249@1|root,COG1249@2|Bacteria,1TQFH@1239|Firmicutes,4HCT8@91061|Bacilli,27DKE@186827|Aerococcaceae 91061|Bacilli C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim gnl|extdb|FAM24227-i1-1.1_001018 1408438.JADD01000017_gene1441 4.11e-57 184.0 2DPA1@1|root,32UKK@2|Bacteria,1VCRN@1239|Firmicutes,4HM9E@91061|Bacilli,27EWD@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - Peptidase_C39_2 gnl|extdb|FAM24227-i1-1.1_001019 883113.HMPREF9708_00483 6.98e-177 504.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,27EGQ@186827|Aerococcaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_001020 592010.GCWU000182_001324 1.58e-114 347.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,27DT7@186827|Aerococcaceae 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C gnl|extdb|FAM24227-i1-1.1_001021 883112.HMPREF9707_00328 2.57e-182 514.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,27DF4@186827|Aerococcaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold mocA - - - - - - - - - - - GFO_IDH_MocA gnl|extdb|FAM24227-i1-1.1_001022 883112.HMPREF9707_00327 1.43e-271 759.0 COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,27EBP@186827|Aerococcaceae 91061|Bacilli E Peptidase family M3 pepF - - - - - - - - - - - Peptidase_M3 gnl|extdb|FAM24227-i1-1.1_001023 1408438.JADD01000017_gene1439 0.0 950.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,27DIC@186827|Aerococcaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N gnl|extdb|FAM24227-i1-1.1_001024 883112.HMPREF9707_00324 1.44e-151 446.0 COG1376@1|root,COG1376@2|Bacteria,1VSWV@1239|Firmicutes,4HT9X@91061|Bacilli,27EI6@186827|Aerococcaceae 91061|Bacilli S L,D-transpeptidase catalytic domain - - - - - - - - - - - - PG_binding_4,YkuD gnl|extdb|FAM24227-i1-1.1_001025 1121871.AUAT01000006_gene1547 7.37e-287 790.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,27DDR@186827|Aerococcaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey gnl|extdb|FAM24227-i1-1.1_001026 883110.HMPREF9260_00847 5.56e-245 685.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,27DQV@186827|Aerococcaceae 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase gnl|extdb|FAM24227-i1-1.1_001027 592010.GCWU000182_000548 5.79e-33 117.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,27E83@186827|Aerococcaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln gnl|extdb|FAM24227-i1-1.1_001028 1408438.JADD01000017_gene1429 9.18e-174 498.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,27DP8@186827|Aerococcaceae 91061|Bacilli S CamS sex pheromone cAM373 precursor camS - - - - - - - - - - - CamS gnl|extdb|FAM24227-i1-1.1_001029 592010.GCWU000182_000550 4.56e-298 835.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,27DPJ@186827|Aerococcaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 gnl|extdb|FAM24227-i1-1.1_001030 1408438.JADD01000017_gene1427 0.0 968.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,27DHD@186827|Aerococcaceae 91061|Bacilli L UvrD-like helicase C-terminal domain pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C gnl|extdb|FAM24227-i1-1.1_001031 908337.HMPREF9257_1526 5.78e-161 463.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,27DNB@186827|Aerococcaceae 91061|Bacilli F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purK2 - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp gnl|extdb|FAM24227-i1-1.1_001032 1121871.AUAT01000006_gene1554 2.07e-78 242.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,27DXH@186827|Aerococcaceae 91061|Bacilli NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG gnl|extdb|FAM24227-i1-1.1_001033 883112.HMPREF9707_00306 1.4e-92 273.0 294TG@1|root,2ZS6Q@2|Bacteria,1V4GD@1239|Firmicutes,4HI6D@91061|Bacilli,27DXG@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001034 592010.GCWU000182_000460 2.74e-32 120.0 COG4129@1|root,COG4129@2|Bacteria,1VAJG@1239|Firmicutes,4HKDZ@91061|Bacilli,27E91@186827|Aerococcaceae 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - ArAE_1,FUSC_2 gnl|extdb|FAM24227-i1-1.1_001036 883112.HMPREF9707_01383 4.01e-171 551.0 COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,27DSZ@186827|Aerococcaceae 91061|Bacilli V Efflux ABC transporter, permease protein - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD gnl|extdb|FAM24227-i1-1.1_001037 883112.HMPREF9707_01382 1.93e-114 333.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,27DK3@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001038 883110.HMPREF9260_00856 2.21e-136 402.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,27DMB@186827|Aerococcaceae 91061|Bacilli J S-adenosylmethionine-dependent methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM gnl|extdb|FAM24227-i1-1.1_001039 883112.HMPREF9707_01380 5.27e-54 190.0 2EHUV@1|root,33BKH@2|Bacteria,1VNPD@1239|Firmicutes,4HR3Y@91061|Bacilli,27E9V@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001041 592010.GCWU000182_001690 4.58e-147 425.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HBKA@91061|Bacilli,27EI5@186827|Aerococcaceae 91061|Bacilli M Glycosyltransferase Family 4 dgs - 2.4.1.208 ko:K13677 ko00561,ko01100,map00561,map01100 - R05164 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_001042 1408438.JADD01000005_gene1240 1.83e-25 99.0 2EKCP@1|root,33E2Z@2|Bacteria,1VM5I@1239|Firmicutes,4HSU9@91061|Bacilli,27E9S@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001043 883113.HMPREF9708_00962 2.68e-98 296.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,27DWM@186827|Aerococcaceae 91061|Bacilli S Cof-like hydrolase - - - - - - - - - - - - Hydrolase_3 gnl|extdb|FAM24227-i1-1.1_001044 1123302.KB904156_gene1557 3.74e-73 236.0 COG0657@1|root,COG0657@2|Bacteria,1V1HV@1239|Firmicutes,4HE9T@91061|Bacilli 91061|Bacilli I Esterase - - - - - - - - - - - - Abhydrolase_3 gnl|extdb|FAM24227-i1-1.1_001045 866775.HMPREF9243_1172 2.79e-78 241.0 COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,4HE6G@91061|Bacilli,27DX4@186827|Aerococcaceae 91061|Bacilli E azaleucine resistance protein AzlC azlC - - - - - - - - - - - AzlC gnl|extdb|FAM24227-i1-1.1_001046 1408438.JADD01000005_gene1237 7.43e-32 115.0 COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,4HJID@91061|Bacilli,27E6M@186827|Aerococcaceae 91061|Bacilli E Branched-chain amino acid transport protein AzlD azlD - - - - - - - - - - - AzlD gnl|extdb|FAM24227-i1-1.1_001047 1408438.JADD01000005_gene1235 5.91e-300 830.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,27DMZ@186827|Aerococcaceae 91061|Bacilli J Arginyl tRNA synthetase N terminal dom argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d gnl|extdb|FAM24227-i1-1.1_001049 908337.HMPREF9257_0274 6.67e-98 293.0 COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HJV9@91061|Bacilli,27F3S@186827|Aerococcaceae 91061|Bacilli M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase gnl|extdb|FAM24227-i1-1.1_001050 1408438.JADD01000005_gene1233 0.0 1212.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,27DTE@186827|Aerococcaceae 91061|Bacilli P potassium sodium efflux P-type ATPase, fungal-type pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase gnl|extdb|FAM24227-i1-1.1_001051 1122129.AUEF01000001_gene759 1.31e-119 351.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,4GXCD@90964|Staphylococcaceae 91061|Bacilli F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06620 GHMP_kinases_C,GHMP_kinases_N gnl|extdb|FAM24227-i1-1.1_001052 1408438.JADD01000005_gene1230 2.27e-134 397.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,27DVJ@186827|Aerococcaceae 91061|Bacilli E Homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 gnl|extdb|FAM24227-i1-1.1_001035 1408438.JADD01000017_gene1423 3.26e-124 388.0 COG2367@1|root,COG2367@2|Bacteria,1VSES@1239|Firmicutes,4HTZF@91061|Bacilli,27EFZ@186827|Aerococcaceae 91061|Bacilli V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 gnl|extdb|FAM24227-i1-1.1_001048 1121871.AUAT01000023_gene1069 1.46e-134 449.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,27EBG@186827|Aerococcaceae 91061|Bacilli M cell wall anchor domain protein - - - ko:K14192 ko05150,map05150 - - - ko00000,ko00001 - - - CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,YSIRK_signal gnl|extdb|FAM24227-i1-1.1_001053 416870.llmg_0703 8.28e-74 240.0 COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,4HG6W@91061|Bacilli 91061|Bacilli L FOG Transposase and inactivated - - - - - - - - - - - - DDE_Tnp_1 gnl|extdb|FAM24227-i1-1.1_001054 862517.HMPREF9225_1185 1.77e-53 170.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,248IJ@186801|Clostridia,22H43@1570339|Peptoniphilaceae 186801|Clostridia L Integrase core domain protein - - - - - - - - - - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_001055 1158607.UAU_01396 3.01e-44 151.0 COG3247@1|root,COG3247@2|Bacteria,1V759@1239|Firmicutes,4HK5F@91061|Bacilli,4B1U5@81852|Enterococcaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 gnl|extdb|FAM24227-i1-1.1_001056 910313.HMPREF9320_0344 1.26e-73 224.0 COG3613@1|root,COG3613@2|Bacteria,1V3SN@1239|Firmicutes,4HH4T@91061|Bacilli 91061|Bacilli F nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr gnl|extdb|FAM24227-i1-1.1_001057 1408438.JADD01000005_gene1150 4.95e-233 657.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,27ED3@186827|Aerococcaceae 91061|Bacilli FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA gnl|extdb|FAM24227-i1-1.1_001059 1121871.AUAT01000007_gene1640 0.0 953.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,27DRS@186827|Aerococcaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn gnl|extdb|FAM24227-i1-1.1_001060 908337.HMPREF9257_1789 4.08e-205 570.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,27EEM@186827|Aerococcaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH gnl|extdb|FAM24227-i1-1.1_001061 883112.HMPREF9707_00224 9.8e-133 380.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,27DSJ@186827|Aerococcaceae 91061|Bacilli K Transcriptional regulator yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg gnl|extdb|FAM24227-i1-1.1_001063 1121871.AUAT01000007_gene1611 3.35e-82 250.0 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,27DWZ@186827|Aerococcaceae 91061|Bacilli S CBS domain acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS gnl|extdb|FAM24227-i1-1.1_001064 1408438.JADD01000014_gene570 1.53e-123 357.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,27DJ3@186827|Aerococcaceae 91061|Bacilli E ABC transporter, ATP-binding protein livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001065 1408438.JADD01000014_gene571 1.19e-139 399.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,27DKY@186827|Aerococcaceae 91061|Bacilli E ABC transporter, ATP-binding protein livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C gnl|extdb|FAM24227-i1-1.1_001066 1408438.JADD01000014_gene572 1.14e-148 427.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,27DHU@186827|Aerococcaceae 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 gnl|extdb|FAM24227-i1-1.1_001067 1408438.JADD01000014_gene573 1.96e-136 394.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,27DJC@186827|Aerococcaceae 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 gnl|extdb|FAM24227-i1-1.1_001068 1408438.JADD01000014_gene574 1.56e-149 435.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27DIN@186827|Aerococcaceae 91061|Bacilli E Receptor family ligand-binding protein livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 gnl|extdb|FAM24227-i1-1.1_001069 1408438.JADD01000014_gene575 4.43e-139 403.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HAFF@91061|Bacilli,27ENQ@186827|Aerococcaceae 91061|Bacilli C lactate/malate dehydrogenase, alpha/beta C-terminal domain - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N gnl|extdb|FAM24227-i1-1.1_001070 1408438.JADD01000014_gene576 3.38e-192 543.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27DIN@186827|Aerococcaceae 91061|Bacilli E Receptor family ligand-binding protein livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 gnl|extdb|FAM24227-i1-1.1_001071 883113.HMPREF9708_00882 7.26e-205 584.0 COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HDT2@91061|Bacilli,27EE3@186827|Aerococcaceae 91061|Bacilli S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 gnl|extdb|FAM24227-i1-1.1_001072 226185.EF_1941 1.6e-07 54.3 2ERDS@1|root,33IZC@2|Bacteria,1VV21@1239|Firmicutes,4HVSG@91061|Bacilli,4B2IC@81852|Enterococcaceae 91061|Bacilli S Protein of unknown function (DUF3224) - - - - - - - - - - - - DUF3224 gnl|extdb|FAM24227-i1-1.1_001073 1408438.JADD01000019_gene840 1.31e-224 634.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli,27DN4@186827|Aerococcaceae 91061|Bacilli E Threonine synthase N terminus thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N gnl|extdb|FAM24227-i1-1.1_001075 1408438.JADD01000014_gene601 1.26e-51 169.0 COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,4HMP7@91061|Bacilli,27E8T@186827|Aerococcaceae 91061|Bacilli K Acetyltransferase GNAT Family - - - - - - - - - - - - Acetyltransf_1 gnl|extdb|FAM24227-i1-1.1_001076 1408438.JADD01000014_gene603 5.84e-121 352.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,27DCS@186827|Aerococcaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 gnl|extdb|FAM24227-i1-1.1_001077 1121871.AUAT01000010_gene650 5.82e-133 383.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,27DG6@186827|Aerococcaceae 91061|Bacilli P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ gnl|extdb|FAM24227-i1-1.1_001078 908337.HMPREF9257_0106 3.97e-130 379.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,27DT3@186827|Aerococcaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001079 592010.GCWU000182_000807 2.13e-129 375.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,27DSG@186827|Aerococcaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001080 883110.HMPREF9260_01476 2.92e-71 216.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,27E19@186827|Aerococcaceae 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 gnl|extdb|FAM24227-i1-1.1_001081 883112.HMPREF9707_00212 1.02e-193 541.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,27DSQ@186827|Aerococcaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L gnl|extdb|FAM24227-i1-1.1_001082 883112.HMPREF9707_00211 1.48e-75 227.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,27DYQ@186827|Aerococcaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 gnl|extdb|FAM24227-i1-1.1_001083 883112.HMPREF9707_00210 5.34e-62 192.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,27DWC@186827|Aerococcaceae 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 gnl|extdb|FAM24227-i1-1.1_001084 883113.HMPREF9708_00871 1.42e-18 76.3 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,27EZF@186827|Aerococcaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 gnl|extdb|FAM24227-i1-1.1_001085 1229520.ADIAL_0635 5.69e-44 142.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,27GMT@186828|Carnobacteriaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a gnl|extdb|FAM24227-i1-1.1_001086 883112.HMPREF9707_00208 2.63e-123 355.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,27DU1@186827|Aerococcaceae 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid gnl|extdb|FAM24227-i1-1.1_001087 883112.HMPREF9707_00207 1.01e-231 647.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,27DIJ@186827|Aerococcaceae 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY gnl|extdb|FAM24227-i1-1.1_001088 592010.GCWU000182_000815 1.15e-82 246.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,27DX1@186827|Aerococcaceae 91061|Bacilli J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A gnl|extdb|FAM24227-i1-1.1_001089 883113.HMPREF9708_00866 4.11e-27 99.4 COG1841@1|root,COG1841@2|Bacteria,1TX5U@1239|Firmicutes,4I625@91061|Bacilli,27E5D@186827|Aerococcaceae 91061|Bacilli J Ribosomal protein L30p/L7e rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 gnl|extdb|FAM24227-i1-1.1_001090 1121871.AUAT01000010_gene662 4.47e-97 284.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,27DVE@186827|Aerococcaceae 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C gnl|extdb|FAM24227-i1-1.1_001091 1121871.AUAT01000010_gene663 2.67e-59 185.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,27E0Z@186827|Aerococcaceae 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p gnl|extdb|FAM24227-i1-1.1_001092 883112.HMPREF9707_00202 1.29e-99 291.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,27DUW@186827|Aerococcaceae 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 gnl|extdb|FAM24227-i1-1.1_001093 883110.HMPREF9260_01489 2.34e-73 221.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,27DZH@186827|Aerococcaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 gnl|extdb|FAM24227-i1-1.1_001094 883112.HMPREF9707_00200 9.69e-38 126.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,27E7K@186827|Aerococcaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 gnl|extdb|FAM24227-i1-1.1_001095 883112.HMPREF9707_00199 2.26e-110 319.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,27DEF@186827|Aerococcaceae 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C gnl|extdb|FAM24227-i1-1.1_001096 1408438.JADD01000014_gene621 8.77e-54 169.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,27E31@186827|Aerococcaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 gnl|extdb|FAM24227-i1-1.1_001097 883113.HMPREF9708_00859 4.07e-76 228.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,27DX9@186827|Aerococcaceae 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 gnl|extdb|FAM24227-i1-1.1_001098 592010.GCWU000182_000824 8.75e-44 143.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,27E33@186827|Aerococcaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 gnl|extdb|FAM24227-i1-1.1_001099 1408438.JADD01000014_gene624 6.38e-31 109.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,27E4Z@186827|Aerococcaceae 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 gnl|extdb|FAM24227-i1-1.1_001100 1121871.AUAT01000010_gene672 4.61e-97 282.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,27DU9@186827|Aerococcaceae 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 gnl|extdb|FAM24227-i1-1.1_001101 883112.HMPREF9707_00193 6.51e-138 392.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,27DI0@186827|Aerococcaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C gnl|extdb|FAM24227-i1-1.1_001102 1121871.AUAT01000010_gene674 1.5e-67 206.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,27DYP@186827|Aerococcaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 gnl|extdb|FAM24227-i1-1.1_001103 883113.HMPREF9708_00853 2.33e-57 178.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,27E18@186827|Aerococcaceae 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 gnl|extdb|FAM24227-i1-1.1_001104 1408438.JADD01000014_gene629 2.75e-184 514.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,27DEC@186827|Aerococcaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C gnl|extdb|FAM24227-i1-1.1_001105 883112.HMPREF9707_00189 5.13e-49 157.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,27E2D@186827|Aerococcaceae 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 gnl|extdb|FAM24227-i1-1.1_001106 1408438.JADD01000014_gene631 1.26e-111 324.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,27DQI@186827|Aerococcaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 gnl|extdb|FAM24227-i1-1.1_001107 883112.HMPREF9707_00187 3.35e-129 369.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,27DEY@186827|Aerococcaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 gnl|extdb|FAM24227-i1-1.1_001108 883112.HMPREF9707_00186 1.75e-63 194.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,27E0F@186827|Aerococcaceae 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 gnl|extdb|FAM24227-i1-1.1_001109 1229520.ADIAL_0165 4.72e-126 366.0 COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,4HBI5@91061|Bacilli,27FZK@186828|Carnobacteriaceae 91061|Bacilli P Phosphonate ABC transporter permease phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001111 1123405.AUMM01000004_gene668 2.42e-132 381.0 COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,26NPU@186821|Sporolactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001112 1229520.ADIAL_0168 3.32e-165 472.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBU5@91061|Bacilli,27G09@186828|Carnobacteriaceae 91061|Bacilli P phosphonate ABC transporter phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd gnl|extdb|FAM24227-i1-1.1_001113 1408438.JADD01000024_gene1281 5.84e-262 732.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,27DNE@186827|Aerococcaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_001114 866775.HMPREF9243_1813 2.22e-219 618.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,27EHH@186827|Aerococcaceae 91061|Bacilli E Argininosuccinate lyase C-terminal argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 gnl|extdb|FAM24227-i1-1.1_001115 1121024.AUCD01000013_gene155 3.22e-223 623.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,27FDS@186828|Carnobacteriaceae 91061|Bacilli E Arginosuccinate synthase argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth gnl|extdb|FAM24227-i1-1.1_001116 1121024.AUCD01000014_gene1857 4.5e-126 376.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,27H3R@186828|Carnobacteriaceae 91061|Bacilli E Peptidase dimerisation domain - - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 gnl|extdb|FAM24227-i1-1.1_001117 1408438.JADD01000017_gene1417 6.42e-67 216.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HIA7@91061|Bacilli 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins - - - - - - - - - - - - SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_001062 333138.LQ50_03745 1.04e-56 181.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,1ZGBN@1386|Bacillus 91061|Bacilli O Belongs to the glutathione peroxidase family bsaA - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx gnl|extdb|FAM24227-i1-1.1_001110 1229520.ADIAL_0166 3.26e-126 367.0 COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,27FWF@186828|Carnobacteriaceae 91061|Bacilli P Phosphonate ABC transporter permease phnB - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001118 883112.HMPREF9707_00158 0.0 1014.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,27DPZ@186827|Aerococcaceae 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 gnl|extdb|FAM24227-i1-1.1_001119 883112.HMPREF9707_00157 2.59e-100 293.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,27DW1@186827|Aerococcaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran gnl|extdb|FAM24227-i1-1.1_001120 883112.HMPREF9707_00156 8.09e-125 379.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,27DHI@186827|Aerococcaceae 91061|Bacilli J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C gnl|extdb|FAM24227-i1-1.1_001121 1408438.JADD01000010_gene1919 9.03e-55 182.0 COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,4HHZ7@91061|Bacilli 91061|Bacilli S hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 gnl|extdb|FAM24227-i1-1.1_001122 1140002.I570_02813 1.27e-96 288.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HGB5@91061|Bacilli,4B06Z@81852|Enterococcaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C gnl|extdb|FAM24227-i1-1.1_001123 883112.HMPREF9707_00154 1.56e-109 330.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS5F@91061|Bacilli 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA gnl|extdb|FAM24227-i1-1.1_001124 883112.HMPREF9707_00151 7.19e-50 165.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,27E0R@186827|Aerococcaceae 91061|Bacilli J S1 RNA binding domain protein yabR - - ko:K07571 - - - - ko00000 - - - S1 gnl|extdb|FAM24227-i1-1.1_001125 1408438.JADD01000013_gene1736 3.16e-11 63.9 28VBH@1|root,2ZHE9@2|Bacteria,1TVPB@1239|Firmicutes,4HQD0@91061|Bacilli,27EZ8@186827|Aerococcaceae 91061|Bacilli S Septum formation initiator - - - - - - - - - - - - DivIC gnl|extdb|FAM24227-i1-1.1_001126 592010.GCWU000182_001888 3.69e-37 127.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,27E51@186827|Aerococcaceae 91061|Bacilli J S4 domain protein yabO - - - - - - - - - - - S4 gnl|extdb|FAM24227-i1-1.1_001127 883112.HMPREF9707_00148 0.0 1426.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,27DDU@186827|Aerococcaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF gnl|extdb|FAM24227-i1-1.1_001128 1408438.JADD01000013_gene1733 5.87e-88 263.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,27DU4@186827|Aerococcaceae 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro gnl|extdb|FAM24227-i1-1.1_001129 592010.GCWU000182_001891 3.85e-175 494.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,27DPK@186827|Aerococcaceae 91061|Bacilli C Belongs to the LDH MDH superfamily ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N gnl|extdb|FAM24227-i1-1.1_001130 1408438.JADD01000013_gene1732 3.55e-36 123.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,27E7T@186827|Aerococcaceae 91061|Bacilli S Biofilm formation stimulator VEG veg - - - - - - - - - - - VEG gnl|extdb|FAM24227-i1-1.1_001131 1121871.AUAT01000010_gene702 1.19e-124 364.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,27DJF@186827|Aerococcaceae 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD gnl|extdb|FAM24227-i1-1.1_001132 908337.HMPREF9257_0159 2.1e-65 206.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,27E6Y@186827|Aerococcaceae 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 gnl|extdb|FAM24227-i1-1.1_001133 908337.HMPREF9257_0160 1.94e-145 414.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,27DPH@186827|Aerococcaceae 91061|Bacilli L TatD related DNase tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase gnl|extdb|FAM24227-i1-1.1_001134 883112.HMPREF9707_00133 0.0 981.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,27DTF@186827|Aerococcaceae 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind gnl|extdb|FAM24227-i1-1.1_001135 1121871.AUAT01000010_gene706 4.72e-94 305.0 COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1V7MV@1239|Firmicutes,4HCQ2@91061|Bacilli,27DFS@186827|Aerococcaceae 91061|Bacilli M NlpC/P60 family spr7 - - ko:K19224,ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM,NLPC_P60,SH3_3 gnl|extdb|FAM24227-i1-1.1_001136 592010.GCWU000182_001876 1.61e-242 673.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,27DQQ@186827|Aerococcaceae 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b gnl|extdb|FAM24227-i1-1.1_001137 888064.HMPREF9088_1770 3.35e-07 49.3 2DRCG@1|root,33B7G@2|Bacteria,1VM0D@1239|Firmicutes,4HRWT@91061|Bacilli,4B5RS@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001138 592010.GCWU000182_000852 1.67e-69 219.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HIR3@91061|Bacilli,27E80@186827|Aerococcaceae 91061|Bacilli S Flavodoxin-like fold yrkL - - - - - - - - - - - Flavodoxin_2 gnl|extdb|FAM24227-i1-1.1_001140 1408438.JADD01000013_gene1723 2.77e-214 606.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,27DGN@186827|Aerococcaceae 91061|Bacilli T ATPase histidine kinase DNA gyrase B HSP90 domain protein yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA gnl|extdb|FAM24227-i1-1.1_001142 883112.HMPREF9707_00121 3.32e-40 138.0 COG0629@1|root,COG0629@2|Bacteria,1VABE@1239|Firmicutes,4HMEE@91061|Bacilli,27E6B@186827|Aerococcaceae 91061|Bacilli L Single-strand binding protein family - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB gnl|extdb|FAM24227-i1-1.1_001143 883113.HMPREF9708_00809 3.47e-164 466.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,27DCI@186827|Aerococcaceae 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N gnl|extdb|FAM24227-i1-1.1_001144 1121871.AUAT01000019_gene136 8.84e-180 508.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,27DK5@186827|Aerococcaceae 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 gnl|extdb|FAM24227-i1-1.1_001145 1408438.JADD01000013_gene1718 1.04e-165 468.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,27DQZ@186827|Aerococcaceae 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 gnl|extdb|FAM24227-i1-1.1_001146 1408438.JADD01000013_gene1717 1.64e-304 843.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,27DPF@186827|Aerococcaceae 91061|Bacilli G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV gnl|extdb|FAM24227-i1-1.1_001148 883113.HMPREF9708_00804 1.76e-144 418.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,27DRI@186827|Aerococcaceae 91061|Bacilli I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N gnl|extdb|FAM24227-i1-1.1_001149 908337.HMPREF9257_0176 1.67e-106 317.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,27DDB@186827|Aerococcaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT gnl|extdb|FAM24227-i1-1.1_001150 1121871.AUAT01000019_gene130 5.28e-151 432.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,27DP4@186827|Aerococcaceae 91061|Bacilli T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N gnl|extdb|FAM24227-i1-1.1_001151 883112.HMPREF9707_01076 2.89e-34 120.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli,27E9Z@186827|Aerococcaceae 91061|Bacilli KT PspC domain pspC - - - - - - - - - - - PspC gnl|extdb|FAM24227-i1-1.1_001152 883112.HMPREF9707_01075 1.63e-46 177.0 COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,27E7R@186827|Aerococcaceae 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 gnl|extdb|FAM24227-i1-1.1_001153 525379.HMPREF0819_1398 3.85e-129 377.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_001154 866775.HMPREF9243_0956 3.02e-112 328.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,27ERB@186827|Aerococcaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP gnl|extdb|FAM24227-i1-1.1_001155 1095737.HMPREF1110_0219 0.0 929.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,2TPCU@28037|Streptococcus mitis 91061|Bacilli C C-terminal domain of alpha-glycerophosphate oxidase glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C gnl|extdb|FAM24227-i1-1.1_001156 1297534.CAUJ01000007_gene1781 1.62e-314 862.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N gnl|extdb|FAM24227-i1-1.1_001157 467705.SGO_0633 3.2e-80 264.0 COG3711@1|root,COG3711@2|Bacteria,1V0R0@1239|Firmicutes,4HE1S@91061|Bacilli 91061|Bacilli K Mga helix-turn-helix domain XK27_00195 - - - - - - - - - - - Mga gnl|extdb|FAM24227-i1-1.1_001158 592010.GCWU000182_001335 7.89e-108 333.0 COG0446@1|root,COG0446@2|Bacteria,1UYBZ@1239|Firmicutes,4HAD3@91061|Bacilli 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase XK27_00190 - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim gnl|extdb|FAM24227-i1-1.1_001159 883112.HMPREF9707_01073 0.0 1518.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,27DG9@186827|Aerococcaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001141 883112.HMPREF9707_00122 2.39e-134 384.0 COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,27DKQ@186827|Aerococcaceae 91061|Bacilli KT Response regulator receiver domain protein yclJ - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C gnl|extdb|FAM24227-i1-1.1_001147 908337.HMPREF9257_0174 5.83e-161 458.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,27DKW@186827|Aerococcaceae 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 gnl|extdb|FAM24227-i1-1.1_001160 1201292.DR75_1741 1.04e-69 225.0 28P3D@1|root,2ZBZ3@2|Bacteria,1V1XD@1239|Firmicutes,4HGF1@91061|Bacilli,4B3NH@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - EcsC gnl|extdb|FAM24227-i1-1.1_001161 945021.TEH_23420 2.9e-72 225.0 arCOG11509@1|root,31KIR@2|Bacteria,1V4KH@1239|Firmicutes,4HPBS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001163 1121105.ATXL01000028_gene670 4.13e-311 848.0 COG4325@1|root,COG4325@2|Bacteria,1TSID@1239|Firmicutes,4HDM1@91061|Bacilli 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 gnl|extdb|FAM24227-i1-1.1_001164 1121105.ATXL01000028_gene669 4.4e-101 293.0 arCOG10217@1|root,301DU@2|Bacteria,1V1QT@1239|Firmicutes,4HG9A@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4385) - - - - - - - - - - - - DUF4385 gnl|extdb|FAM24227-i1-1.1_001167 1123075.AUDP01000028_gene1956 1.6e-08 65.9 COG1657@1|root,COG2340@1|root,COG5492@1|root,COG1657@2|Bacteria,COG2340@2|Bacteria,COG5492@2|Bacteria,1UYXV@1239|Firmicutes,24CMK@186801|Clostridia 186801|Clostridia I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001168 883110.HMPREF9260_00726 1.33e-75 232.0 2ADW4@1|root,313N4@2|Bacteria,1V790@1239|Firmicutes,4HQX4@91061|Bacilli,27EZ6@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF4230) - - - - - - - - - - - - DUF4230 gnl|extdb|FAM24227-i1-1.1_001169 1297857.CAUK01000004_gene850 0.000671 42.7 2DQXV@1|root,3399Y@2|Bacteria,1VDDK@1239|Firmicutes,4HMPQ@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - TPR_12,TPR_8 gnl|extdb|FAM24227-i1-1.1_001171 1027396.LMOSA_12100 4.87e-138 400.0 COG1715@1|root,COG1715@2|Bacteria,1V1TA@1239|Firmicutes,4HC3T@91061|Bacilli,26M3Z@186820|Listeriaceae 91061|Bacilli V Restriction endonuclease mrr2 - - ko:K07448 - - - - ko00000,ko02048 - - - MerR_1,Mrr_N,Mrr_cat gnl|extdb|FAM24227-i1-1.1_001172 1002809.SSIL_3346 4.03e-32 119.0 COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,4HG4Q@91061|Bacilli,26HGB@186818|Planococcaceae 91061|Bacilli L RadC-like JAB domain - - - ko:K03630 - - - - ko00000 - - - RadC gnl|extdb|FAM24227-i1-1.1_001174 1123315.AUIP01000001_gene1602 1.37e-20 88.6 COG4333@1|root,COG4333@2|Bacteria,1VI5E@1239|Firmicutes,4HQ54@91061|Bacilli 91061|Bacilli V Protein of unknown function (DUF1643) - - - - - - - - - - - - DUF1643 gnl|extdb|FAM24227-i1-1.1_001175 467705.SGO_1119 5.21e-16 82.8 COG2865@1|root,COG2865@2|Bacteria,1UYYR@1239|Firmicutes,4HHVE@91061|Bacilli 91061|Bacilli K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 gnl|extdb|FAM24227-i1-1.1_001176 1449343.JQLQ01000002_gene120 1.24e-28 114.0 COG2865@1|root,COG2865@2|Bacteria,1UYYR@1239|Firmicutes,4HHVE@91061|Bacilli,27HKY@186828|Carnobacteriaceae 91061|Bacilli K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 gnl|extdb|FAM24227-i1-1.1_001177 1462527.CCDM010000001_gene1937 1.08e-63 201.0 COG0503@1|root,COG0503@2|Bacteria,1V1XS@1239|Firmicutes,4HG1T@91061|Bacilli,23KE3@182709|Oceanobacillus 91061|Bacilli F Phosphoribosyl transferase domain - - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran gnl|extdb|FAM24227-i1-1.1_001178 1410653.JHVC01000001_gene1565 1.25e-120 359.0 COG0659@1|root,COG0659@2|Bacteria,1UY33@1239|Firmicutes,24942@186801|Clostridia,36HSM@31979|Clostridiaceae 186801|Clostridia P secondary active sulfate transmembrane transporter activity - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - BenE,Xan_ur_permease gnl|extdb|FAM24227-i1-1.1_001179 1408438.JADD01000005_gene1193 7.74e-79 238.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,27DYY@186827|Aerococcaceae 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase gnl|extdb|FAM24227-i1-1.1_001180 1408438.JADD01000005_gene1192 4.92e-161 470.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,27DVA@186827|Aerococcaceae 91061|Bacilli P Cation transport protein ntpJ - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH gnl|extdb|FAM24227-i1-1.1_001181 1121871.AUAT01000013_gene338 1.75e-109 320.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,27DRD@186827|Aerococcaceae 91061|Bacilli P TrkA-N domain ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N gnl|extdb|FAM24227-i1-1.1_001182 883112.HMPREF9707_01088 1.44e-148 434.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,27DF3@186827|Aerococcaceae 91061|Bacilli O Trypsin htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 gnl|extdb|FAM24227-i1-1.1_001183 1408438.JADD01000012_gene1639 2.81e-141 407.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,27DRT@186827|Aerococcaceae 91061|Bacilli S Metallo-beta-lactamase domain protein vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 gnl|extdb|FAM24227-i1-1.1_001184 883112.HMPREF9707_01086 1.25e-200 584.0 COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,4HF7D@91061|Bacilli,27DN9@186827|Aerococcaceae 91061|Bacilli S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 gnl|extdb|FAM24227-i1-1.1_001185 883112.HMPREF9707_01085 4.71e-104 311.0 COG4853@1|root,COG4853@2|Bacteria,1V2BD@1239|Firmicutes,4HG92@91061|Bacilli,27DYW@186827|Aerococcaceae 91061|Bacilli S YycH protein - - - - - - - - - - - - YycI gnl|extdb|FAM24227-i1-1.1_001186 883112.HMPREF9707_01084 6.5e-110 340.0 COG4863@1|root,COG4863@2|Bacteria 2|Bacteria S YycH protein yycH - - - - - - - - - - - YycH gnl|extdb|FAM24227-i1-1.1_001187 883112.HMPREF9707_01083 7.35e-295 822.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,27DCA@186827|Aerococcaceae 91061|Bacilli T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 gnl|extdb|FAM24227-i1-1.1_001188 1408438.JADD01000012_gene1634 2.8e-142 404.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,27DDF@186827|Aerococcaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C gnl|extdb|FAM24227-i1-1.1_001189 1121871.AUAT01000013_gene309 4.61e-182 523.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,27DI5@186827|Aerococcaceae 91061|Bacilli S L,D-transpeptidase catalytic domain - - - - - - - - - - - - PG_binding_4,YkuD gnl|extdb|FAM24227-i1-1.1_001190 1408438.JADD01000012_gene1632 3.51e-62 204.0 COG0561@1|root,COG0561@2|Bacteria,1V48M@1239|Firmicutes,4I37M@91061|Bacilli,27ESK@186827|Aerococcaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 gnl|extdb|FAM24227-i1-1.1_001191 883113.HMPREF9708_00757 2.26e-121 350.0 COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli,27DX3@186827|Aerococcaceae 91061|Bacilli S Methyltransferase domain yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 gnl|extdb|FAM24227-i1-1.1_001192 1121871.AUAT01000013_gene305 4.32e-223 628.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,27DDM@186827|Aerococcaceae 91061|Bacilli S Transporter associated domain hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 gnl|extdb|FAM24227-i1-1.1_001193 592010.GCWU000182_000621 3.54e-68 214.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,27E0T@186827|Aerococcaceae 91061|Bacilli S (CBS) domain - - - - - - - - - - - - CBS gnl|extdb|FAM24227-i1-1.1_001194 592010.GCWU000182_000973 1.93e-71 223.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,27DZ1@186827|Aerococcaceae 91061|Bacilli S Metallo-beta-lactamase domain protein XK27_08165 - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B gnl|extdb|FAM24227-i1-1.1_001195 1408438.JADD01000012_gene1627 1.14e-183 521.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,27DRZ@186827|Aerococcaceae 91061|Bacilli M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N gnl|extdb|FAM24227-i1-1.1_001196 1408438.JADD01000012_gene1626 3.25e-35 125.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS gnl|extdb|FAM24227-i1-1.1_001197 592010.GCWU000182_000970 7.02e-232 654.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,27DNQ@186827|Aerococcaceae 91061|Bacilli L Belongs to the DEAD box helicase family cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C gnl|extdb|FAM24227-i1-1.1_001198 883112.HMPREF9707_00109 1.94e-214 606.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,27DIE@186827|Aerococcaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M gnl|extdb|FAM24227-i1-1.1_001199 883112.HMPREF9707_00108 1.55e-179 509.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,27DER@186827|Aerococcaceae 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N gnl|extdb|FAM24227-i1-1.1_001200 1121871.AUAT01000013_gene297 8.98e-113 332.0 29SV9@1|root,30E1E@2|Bacteria,1V46E@1239|Firmicutes,4HI7R@91061|Bacilli,27DMT@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001202 1408438.JADD01000012_gene1620 5.68e-105 314.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,27E2Z@186827|Aerococcaceae 91061|Bacilli S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_001203 908337.HMPREF9257_0905 3.31e-55 189.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,27E2Z@186827|Aerococcaceae 91061|Bacilli S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_001204 1408438.JADD01000012_gene1619 8.43e-68 233.0 2AHKI@1|root,317YB@2|Bacteria,1V965@1239|Firmicutes,4HXW4@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001205 1408438.JADD01000013_gene1752 4.86e-13 63.5 COG2826@1|root,COG2826@2|Bacteria 2|Bacteria L transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_001201 883112.HMPREF9707_00106 1.38e-90 269.0 COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,4HH6H@91061|Bacilli,27DUG@186827|Aerococcaceae 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA gnl|extdb|FAM24227-i1-1.1_001206 1408438.JADD01000008_gene1523 6.03e-38 128.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_001207 1449338.JQLU01000005_gene1536 1.2e-09 58.5 COG2172@1|root,COG2172@2|Bacteria,1VK6N@1239|Firmicutes,4HSBR@91061|Bacilli 91061|Bacilli T sigma factor antagonist activity - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001208 1175629.AJTG01000007_gene1110 2.97e-175 504.0 2DB7K@1|root,2Z7MK@2|Bacteria,1TQ79@1239|Firmicutes,4HCXC@91061|Bacilli,27EMC@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1576) - - - - - - - - - - - - DUF1576 gnl|extdb|FAM24227-i1-1.1_001209 1158614.I592_03512 1.11e-60 193.0 COG1611@1|root,COG1611@2|Bacteria,1V37C@1239|Firmicutes,4IR98@91061|Bacilli 91061|Bacilli S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox gnl|extdb|FAM24227-i1-1.1_001210 1408438.JADD01000004_gene1078 5.58e-84 263.0 COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,27E1T@186827|Aerococcaceae 91061|Bacilli S Putative aromatic acid exporter C-terminal domain yqjA - - - - - - - - - - - ArAE_1,ArAE_1_C gnl|extdb|FAM24227-i1-1.1_001211 1229520.ADIAL_1093 2.38e-43 147.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,27GE5@186828|Carnobacteriaceae 91061|Bacilli S Thioesterase-like superfamily yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 gnl|extdb|FAM24227-i1-1.1_001212 1121871.AUAT01000013_gene291 5.23e-107 311.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,27DWG@186827|Aerococcaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C gnl|extdb|FAM24227-i1-1.1_001213 1408438.JADD01000012_gene1617 1.04e-169 486.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,27DMP@186827|Aerococcaceae 91061|Bacilli E Aminotransferase class I and II - - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_001214 866895.HBHAL_2460 2.03e-15 76.6 28PQP@1|root,2ZCCM@2|Bacteria,1V1II@1239|Firmicutes,4HGJG@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4386) - - - - - - - - - - - - DUF4386 gnl|extdb|FAM24227-i1-1.1_001216 1200792.AKYF01000019_gene4524 8.1e-13 67.0 COG0664@1|root,COG0664@2|Bacteria,1V2E0@1239|Firmicutes,4HG8V@91061|Bacilli,26RP4@186822|Paenibacillaceae 91061|Bacilli T Cyclic nucleotide-binding protein - - - - - - - - - - - - HTH_Crp_2,cNMP_binding gnl|extdb|FAM24227-i1-1.1_001217 1501230.ET33_27140 4.34e-18 81.6 COG0664@1|root,COG0664@2|Bacteria,1V2E0@1239|Firmicutes,4HG8V@91061|Bacilli,26RP4@186822|Paenibacillaceae 91061|Bacilli T Cyclic nucleotide-binding protein - - - - - - - - - - - - HTH_Crp_2,cNMP_binding gnl|extdb|FAM24227-i1-1.1_001218 558169.AGAV01000005_gene1952 1.23e-146 420.0 COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,4HAQT@91061|Bacilli 91061|Bacilli K COG COG0846 NAD-dependent protein deacetylases, SIR2 family - - - - - - - - - - - - SIR2 gnl|extdb|FAM24227-i1-1.1_001219 1159488.SEQMU2_11225 6.66e-90 273.0 COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,4HCXD@91061|Bacilli,4GXTE@90964|Staphylococcaceae 91061|Bacilli S Appr-1'-p processing enzyme - - - - - - - - - - - - Macro gnl|extdb|FAM24227-i1-1.1_001220 558169.AGAV01000005_gene1950 3.56e-44 146.0 COG0509@1|root,COG0509@2|Bacteria,1VAMB@1239|Firmicutes,4HKV0@91061|Bacilli 91061|Bacilli E glycine cleavage - - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H gnl|extdb|FAM24227-i1-1.1_001221 1122143.AUEG01000015_gene1852 2.05e-69 230.0 COG0457@1|root,COG0457@2|Bacteria,1VBH7@1239|Firmicutes,4IS2V@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001222 1449335.JQLG01000004_gene631 1.2e-65 208.0 COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli,27GDA@186828|Carnobacteriaceae 91061|Bacilli L NUDIX domain XK27_06885 - - - - - - - - - - - NUDIX gnl|extdb|FAM24227-i1-1.1_001223 866775.HMPREF9243_0778 2.42e-86 260.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,27E4Q@186827|Aerococcaceae 91061|Bacilli E Serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep gnl|extdb|FAM24227-i1-1.1_001224 655812.HMPREF0061_0776 2.77e-164 466.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,27DXQ@186827|Aerococcaceae 91061|Bacilli E Cysteine synthase A cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP gnl|extdb|FAM24227-i1-1.1_001226 1121289.JHVL01000061_gene2556 1.17e-88 265.0 COG1396@1|root,COG2033@1|root,COG1396@2|Bacteria,COG2033@2|Bacteria,1W1Q8@1239|Firmicutes,25EKH@186801|Clostridia,36UUP@31979|Clostridiaceae 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - Acetyltransf_3,Desulfoferrodox,HTH_3 gnl|extdb|FAM24227-i1-1.1_001227 768710.DesyoDRAFT_2864 4.42e-33 118.0 2DM6H@1|root,31X48@2|Bacteria,1V8E0@1239|Firmicutes,24KN4@186801|Clostridia,2656Z@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001228 883113.HMPREF9708_00563 1.89e-52 165.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HKF0@91061|Bacilli,27E0N@186827|Aerococcaceae 91061|Bacilli J 50S ribosomal protein L31 type B rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 gnl|extdb|FAM24227-i1-1.1_001229 883112.HMPREF9707_00815 7.65e-54 180.0 COG3279@1|root,COG3279@2|Bacteria,1TRDQ@1239|Firmicutes,4HP0H@91061|Bacilli 91061|Bacilli KT COG3279 Response regulator of the LytR AlgR family - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg gnl|extdb|FAM24227-i1-1.1_001230 883112.HMPREF9707_00814 6.35e-68 214.0 COG3290@1|root,COG3290@2|Bacteria,1UDI2@1239|Firmicutes,4HF65@91061|Bacilli 91061|Bacilli T signal transduction protein with a C-terminal ATPase domain - - - - - - - - - - - - HATPase_c_5,SPOB_a gnl|extdb|FAM24227-i1-1.1_001231 883112.HMPREF9707_00812 1.21e-125 390.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,27EQS@186827|Aerococcaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001232 883112.HMPREF9707_00811 6.69e-147 444.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001234 1121024.AUCD01000037_gene425 5.55e-43 145.0 COG0454@1|root,COG0456@2|Bacteria,1UHQS@1239|Firmicutes,4IT2E@91061|Bacilli,27GRJ@186828|Carnobacteriaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 gnl|extdb|FAM24227-i1-1.1_001235 1121871.AUAT01000005_gene1691 9.72e-39 129.0 COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli,27EY0@186827|Aerococcaceae 91061|Bacilli S Transcriptional Coactivator p15 (PC4) XK26_06125 - - - - - - - - - - - PC4 gnl|extdb|FAM24227-i1-1.1_001236 883110.HMPREF9260_01126 2.24e-66 205.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHFK@91061|Bacilli,27F2X@186827|Aerococcaceae 91061|Bacilli S Aminoacyl-tRNA editing domain ebsC - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit gnl|extdb|FAM24227-i1-1.1_001237 1034347.CAHJ01000024_gene3216 4.46e-277 774.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,1ZCHI@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - iYO844.BSU14520 Adenine_deam_C,Amidohydro_1 gnl|extdb|FAM24227-i1-1.1_001238 883112.HMPREF9707_00084 5.44e-266 733.0 COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli,27ECB@186827|Aerococcaceae 91061|Bacilli K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind gnl|extdb|FAM24227-i1-1.1_001239 883113.HMPREF9708_00571 1.09e-252 699.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,27DC2@186827|Aerococcaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase gnl|extdb|FAM24227-i1-1.1_001240 883113.HMPREF9708_00572 7.5e-81 252.0 28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes,4HWD2@91061|Bacilli,27EQH@186827|Aerococcaceae 91061|Bacilli S CRISPR-associated protein (Cas_Csm6) - - - - - - - - - - - - Cas_Csm6 gnl|extdb|FAM24227-i1-1.1_001241 883112.HMPREF9707_00081 7.74e-69 218.0 2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,4HKYW@91061|Bacilli,27EQ8@186827|Aerococcaceae 91061|Bacilli S TraX protein traX - - - - - - - - - - - TraX gnl|extdb|FAM24227-i1-1.1_001242 908337.HMPREF9257_0700 6.6e-63 199.0 2B0QA@1|root,31T2A@2|Bacteria,1V9HP@1239|Firmicutes,4HJK8@91061|Bacilli,27E43@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001243 1408438.JADD01000008_gene1492 1.78e-168 474.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,27DFN@186827|Aerococcaceae 91061|Bacilli G Fructose-1,6-bisphosphate aldolase, class II fbaA - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase gnl|extdb|FAM24227-i1-1.1_001244 1175629.AJTG01000030_gene267 1.79e-201 570.0 COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HATA@91061|Bacilli,27DHE@186827|Aerococcaceae 91061|Bacilli EGP Transporter, major facilitator family protein naiP - - ko:K08196 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,Sugar_tr gnl|extdb|FAM24227-i1-1.1_001246 1175629.AJTG01000030_gene269 3.46e-93 280.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,27DY7@186827|Aerococcaceae 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase gnl|extdb|FAM24227-i1-1.1_001247 883112.HMPREF9707_00078 9.72e-305 840.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,27DMG@186827|Aerococcaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase gnl|extdb|FAM24227-i1-1.1_001249 592010.GCWU000182_001938 1.53e-20 88.6 2E8BT@1|root,332QG@2|Bacteria,1VHMQ@1239|Firmicutes,4HPAT@91061|Bacilli,27E5T@186827|Aerococcaceae 91061|Bacilli S Domain of unknown function (DUF1934) - - - - - - - - - - - - DUF1934 gnl|extdb|FAM24227-i1-1.1_001250 883113.HMPREF9708_00575 5.35e-95 288.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,27E2K@186827|Aerococcaceae 91061|Bacilli H Biotin/lipoate A/B protein ligase family lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB gnl|extdb|FAM24227-i1-1.1_001251 883112.HMPREF9707_00074 1.4e-246 687.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,27DGE@186827|Aerococcaceae 91061|Bacilli S HD domain protein ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD gnl|extdb|FAM24227-i1-1.1_001252 1121024.AUCD01000013_gene158 3.1e-144 422.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,27F93@186828|Carnobacteriaceae 91061|Bacilli E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 gnl|extdb|FAM24227-i1-1.1_001253 1408438.JADD01000006_gene1010 1.83e-89 275.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,27F2Z@186827|Aerococcaceae 91061|Bacilli P NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_001254 883112.HMPREF9707_00071 2.65e-125 366.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,27F2Z@186827|Aerococcaceae 91061|Bacilli P NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_001255 1408438.JADD01000024_gene1293 2.15e-108 324.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,27F2Z@186827|Aerococcaceae 91061|Bacilli P NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_001256 1408438.JADD01000006_gene1010 6.69e-138 398.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,27F2Z@186827|Aerococcaceae 91061|Bacilli P NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_001257 1408438.JADD01000006_gene1008 2.31e-147 429.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,27DMP@186827|Aerococcaceae 91061|Bacilli E Aminotransferase class I and II aspC - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_001215 1501230.ET33_27145 5.27e-06 50.1 28PQP@1|root,2ZCCM@2|Bacteria,1V1II@1239|Firmicutes,4HGJG@91061|Bacilli,26T2P@186822|Paenibacillaceae 91061|Bacilli S Domain of unknown function (DUF4386) - - - - - - - - - - - - DUF4386 gnl|extdb|FAM24227-i1-1.1_001225 1526927.Plano_1714 2.69e-09 53.5 2E3IE@1|root,32YGW@2|Bacteria,1W1H1@1239|Firmicutes,4HYV9@91061|Bacilli 91061|Bacilli S Hexameric tyrosine-coordinated heme protein (HTHP) - - - - - - - - - - - - HTHP gnl|extdb|FAM24227-i1-1.1_001245 883081.HMPREF9698_00413 9.41e-87 262.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,27G5V@186828|Carnobacteriaceae 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran gnl|extdb|FAM24227-i1-1.1_001248 1408438.JADD01000008_gene1491 4.36e-58 190.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,27E16@186827|Aerococcaceae 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH gnl|extdb|FAM24227-i1-1.1_001260 883113.HMPREF9708_00968 1.11e-128 367.0 2EVIX@1|root,33NZ2@2|Bacteria,1VM5V@1239|Firmicutes,4HSE6@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001262 665950.HMPREF1025_00752 1.81e-103 301.0 COG4283@1|root,COG4283@2|Bacteria,1TSF1@1239|Firmicutes,2493R@186801|Clostridia,27QZG@186928|unclassified Lachnospiraceae 186801|Clostridia S Protein of unknown function (DUF1706) - - - - - - - - - - - - DUF1706 gnl|extdb|FAM24227-i1-1.1_001263 203119.Cthe_2971 3.15e-29 114.0 2E33N@1|root,32Y3S@2|Bacteria,1VFAP@1239|Firmicutes,24R1K@186801|Clostridia,3WMAX@541000|Ruminococcaceae 186801|Clostridia S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 gnl|extdb|FAM24227-i1-1.1_001264 445971.ANASTE_01250 1.75e-124 363.0 COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,25VA6@186806|Eubacteriaceae 186801|Clostridia V Psort location CytoplasmicMembrane, score - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001265 203119.Cthe_2969 5.98e-54 172.0 COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3WJES@541000|Ruminococcaceae 186801|Clostridia K Bacterial regulatory proteins, gntR family - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR gnl|extdb|FAM24227-i1-1.1_001267 883112.HMPREF9707_01313 5.8e-220 620.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4H9M0@91061|Bacilli,27EIE@186827|Aerococcaceae 91061|Bacilli H tRNA (Uracil-5-)-methyltransferase - - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - tRNA_U5-meth_tr gnl|extdb|FAM24227-i1-1.1_001268 525919.Apre_1722 0.000502 42.4 COG0347@1|root,COG0347@2|Bacteria,1V20Y@1239|Firmicutes,24G40@186801|Clostridia,22HBI@1570339|Peptoniphilaceae 186801|Clostridia K Belongs to the P(II) protein family - - - - - - - - - - - - P-II gnl|extdb|FAM24227-i1-1.1_001269 596324.TREVI0001_1346 3.43e-06 54.3 COG0347@1|root,COG0347@2|Bacteria,2J7GB@203691|Spirochaetes 203691|Spirochaetes K Belongs to the P(II) protein family - - - - - - - - - - - - P-II gnl|extdb|FAM24227-i1-1.1_001270 883113.HMPREF9708_00125 6.07e-59 201.0 COG0589@1|root,COG0589@2|Bacteria,1TPUI@1239|Firmicutes,4HCC9@91061|Bacilli,27EK0@186827|Aerococcaceae 91061|Bacilli T Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 gnl|extdb|FAM24227-i1-1.1_001271 862517.HMPREF9225_1730 8.73e-43 157.0 COG0589@1|root,COG0589@2|Bacteria,1TPUI@1239|Firmicutes,24826@186801|Clostridia,22GG7@1570339|Peptoniphilaceae 186801|Clostridia T Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 gnl|extdb|FAM24227-i1-1.1_001272 883112.HMPREF9707_01195 3.19e-210 594.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,27DFT@186827|Aerococcaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr gnl|extdb|FAM24227-i1-1.1_001273 1121871.AUAT01000005_gene1726 2.01e-111 335.0 COG3409@1|root,COG3409@2|Bacteria,1V2YC@1239|Firmicutes,4HFNB@91061|Bacilli 91061|Bacilli M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001274 1449335.JQLG01000004_gene740 1.08e-122 361.0 COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,27FGB@186828|Carnobacteriaceae 91061|Bacilli I Steryl acetyl hydrolase - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 gnl|extdb|FAM24227-i1-1.1_001276 1449343.JQLQ01000002_gene476 2.15e-54 180.0 2DBAJ@1|root,2Z83A@2|Bacteria,1V0GH@1239|Firmicutes,4HHTF@91061|Bacilli,27G9I@186828|Carnobacteriaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001277 1449342.JQMR01000001_gene1120 4.12e-50 184.0 COG1388@1|root,COG1705@1|root,COG3064@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,COG3064@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,27FVJ@186828|Carnobacteriaceae 91061|Bacilli MNU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase acmA GO:0005575,GO:0005576 - ko:K02395,ko:K19220,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM gnl|extdb|FAM24227-i1-1.1_001278 33035.JPJF01000017_gene3752 7.56e-23 97.1 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3Y1VI@572511|Blautia 186801|Clostridia G Glycosyl hydrolases family 2, sugar binding domain - - 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N gnl|extdb|FAM24227-i1-1.1_001281 1408438.JADD01000002_gene350 0.0 971.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,27DEI@186827|Aerococcaceae 91061|Bacilli K Tex-like protein N-terminal domain protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF gnl|extdb|FAM24227-i1-1.1_001282 883112.HMPREF9707_00281 6.76e-84 257.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HHQ3@91061|Bacilli,27DXW@186827|Aerococcaceae 91061|Bacilli T Calcineurin-like phosphoesterase pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos gnl|extdb|FAM24227-i1-1.1_001283 883112.HMPREF9707_00280 7.62e-246 687.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,27DGT@186827|Aerococcaceae 91061|Bacilli S Permease family XK27_07275 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease gnl|extdb|FAM24227-i1-1.1_001285 1121024.AUCD01000002_gene1798 3.12e-12 66.6 COG2271@1|root,COG2271@2|Bacteria,1TRHT@1239|Firmicutes,4HDG8@91061|Bacilli,27HMD@186828|Carnobacteriaceae 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 gnl|extdb|FAM24227-i1-1.1_001287 883113.HMPREF9708_00508 4.99e-203 573.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4H9TH@91061|Bacilli,27DT1@186827|Aerococcaceae 91061|Bacilli G Bacterial extracellular solute-binding protein malE - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 gnl|extdb|FAM24227-i1-1.1_001288 1121871.AUAT01000012_gene572 2.11e-154 438.0 COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,27DRJ@186827|Aerococcaceae 91061|Bacilli U Psort location CytoplasmicMembrane, score 10.00 malF - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001289 908337.HMPREF9257_0452 4.8e-162 459.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HBEF@91061|Bacilli,27DEB@186827|Aerococcaceae 91061|Bacilli G ABC transporter, permease protein - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001290 908337.HMPREF9257_0451 4.59e-169 482.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HBKK@91061|Bacilli,27DHC@186827|Aerococcaceae 91061|Bacilli P ABC transporter, ATP-binding protein malK - - ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 - - ABC_tran,TOBE_2 gnl|extdb|FAM24227-i1-1.1_001291 592010.GCWU000182_001595 6.51e-228 647.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,27DH3@186827|Aerococcaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family ycjM - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos gnl|extdb|FAM24227-i1-1.1_001292 883113.HMPREF9708_00513 1.32e-129 389.0 COG0595@1|root,COG0595@2|Bacteria,1V0AV@1239|Firmicutes,4HEB0@91061|Bacilli,27DR8@186827|Aerococcaceae 91061|Bacilli S Metallo-beta-lactamase superfamily YSH1 - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2 gnl|extdb|FAM24227-i1-1.1_001293 1408438.JADD01000002_gene352 2.63e-27 118.0 COG1388@1|root,COG1388@2|Bacteria,1V3R4@1239|Firmicutes,4HHXR@91061|Bacilli,27DWJ@186827|Aerococcaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM gnl|extdb|FAM24227-i1-1.1_001294 883112.HMPREF9707_00276 4.69e-261 735.0 COG1164@1|root,COG1164@2|Bacteria,1TR7D@1239|Firmicutes,4HA0P@91061|Bacilli,27DPC@186827|Aerococcaceae 91061|Bacilli E Peptidase family M3 XK27_00225 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N gnl|extdb|FAM24227-i1-1.1_001295 592010.GCWU000182_001597 1.33e-195 552.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,27DI2@186827|Aerococcaceae 91061|Bacilli E Aminotransferase yugH - - ko:K10907 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_001296 1121871.AUAT01000012_gene580 4.22e-72 221.0 COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,4HH9K@91061|Bacilli,27E4D@186827|Aerococcaceae 91061|Bacilli K Transcriptional regulator, AsnC family alaR - - - - - - - - - - - AsnC_trans_reg,HTH_24 gnl|extdb|FAM24227-i1-1.1_001297 908337.HMPREF9257_0444 2.33e-204 590.0 COG2367@1|root,COG2367@2|Bacteria,1V0TS@1239|Firmicutes,4HBQE@91061|Bacilli,27DJZ@186827|Aerococcaceae 91061|Bacilli V SH3-like domain - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2,SH3_8 gnl|extdb|FAM24227-i1-1.1_001298 1408438.JADD01000002_gene358 2.3e-71 225.0 2EB6M@1|root,3357A@2|Bacteria,1VG1Y@1239|Firmicutes,4HP3G@91061|Bacilli,27E6R@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001299 1175629.AJTG01000002_gene1345 5.84e-129 371.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,27DN6@186827|Aerococcaceae 91061|Bacilli E ATPases associated with a variety of cellular activities glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001301 862517.HMPREF9225_0287 1.22e-127 388.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,22G9N@1570339|Peptoniphilaceae 186801|Clostridia P Chloride transporter, ClC family clcA - - - - - - - - - - - TrkA_C,Voltage_CLC gnl|extdb|FAM24227-i1-1.1_001275 1449342.JQMR01000001_gene1996 1.98e-152 447.0 COG1020@1|root,COG1020@2|Bacteria,1UIW2@1239|Firmicutes,4ISU4@91061|Bacilli,27FR3@186828|Carnobacteriaceae 91061|Bacilli Q Alcohol acetyltransferase - - - - - - - - - - - - AATase gnl|extdb|FAM24227-i1-1.1_001279 33035.JPJF01000017_gene3752 3.19e-44 159.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3Y1VI@572511|Blautia 186801|Clostridia G Glycosyl hydrolases family 2, sugar binding domain - - 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N gnl|extdb|FAM24227-i1-1.1_001300 655812.HMPREF0061_0578 9.58e-302 849.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,27DG8@186827|Aerococcaceae 91061|Bacilli P Bacterial periplasmic substrate-binding proteins glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_001302 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_001304 1449335.JQLG01000004_gene822 2.88e-111 328.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 gnl|extdb|FAM24227-i1-1.1_001306 1449343.JQLQ01000002_gene379 4.99e-93 290.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli 91061|Bacilli I acyl-CoA dehydrogenase acdA - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N gnl|extdb|FAM24227-i1-1.1_001307 908337.HMPREF9257_0416 2.22e-209 587.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,27DK1@186827|Aerococcaceae 91061|Bacilli I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N gnl|extdb|FAM24227-i1-1.1_001309 1282665.H353_03470 1.71e-215 603.0 COG1960@1|root,COG1960@2|Bacteria,1TR1Y@1239|Firmicutes,4HBTJ@91061|Bacilli 91061|Bacilli C Acyl-CoA dehydrogenase, C-terminal domain protein gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N gnl|extdb|FAM24227-i1-1.1_001310 1392838.AWNM01000087_gene3668 9.49e-38 133.0 COG2030@1|root,COG2030@2|Bacteria,1RGUP@1224|Proteobacteria,2VRWK@28216|Betaproteobacteria,3T7HG@506|Alcaligenaceae 28216|Betaproteobacteria I MaoC like domain maoC - - - - - - - - - - - MaoC_dehydratas gnl|extdb|FAM24227-i1-1.1_001311 1139219.I569_01104 1.67e-20 88.6 COG0454@1|root,COG0456@2|Bacteria,1VFVQ@1239|Firmicutes,4HK5T@91061|Bacilli,4B332@81852|Enterococcaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 gnl|extdb|FAM24227-i1-1.1_001312 1220551.SCHR_08924 8.68e-141 414.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HHI7@91061|Bacilli,4H1GI@90964|Staphylococcaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 gnl|extdb|FAM24227-i1-1.1_001313 565653.EGBG_01857 2.11e-82 248.0 COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli,4B11Q@81852|Enterococcaceae 91061|Bacilli S Belongs to the UPF0340 family ywlG - - - - - - - - - - - DUF436 gnl|extdb|FAM24227-i1-1.1_001314 1139996.OMQ_00618 5.93e-58 185.0 COG4720@1|root,COG4720@2|Bacteria,1V1E7@1239|Firmicutes,4HGDE@91061|Bacilli,4B6WD@81852|Enterococcaceae 91061|Bacilli S ECF-type riboflavin transporter, S component hmpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ECF-ribofla_trS gnl|extdb|FAM24227-i1-1.1_001315 138119.DSY3755 1.06e-73 223.0 COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,24BVW@186801|Clostridia,263MB@186807|Peptococcaceae 186801|Clostridia S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt gnl|extdb|FAM24227-i1-1.1_001316 190304.FN0600 2.36e-29 112.0 2E0XQ@1|root,32WEE@2|Bacteria,37AQA@32066|Fusobacteria 32066|Fusobacteria - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001317 1175629.AJTG01000009_gene962 9.24e-28 104.0 COG1416@1|root,COG1416@2|Bacteria,1VEYT@1239|Firmicutes,4HRTF@91061|Bacilli 91061|Bacilli S DsrE/DsrF-like family - - - - - - - - - - - - DrsE gnl|extdb|FAM24227-i1-1.1_001318 1175629.AJTG01000031_gene1536 7.55e-24 101.0 2DZVH@1|root,32VK2@2|Bacteria,1VE5W@1239|Firmicutes,4HRZB@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - SfLAP gnl|extdb|FAM24227-i1-1.1_001319 1175629.AJTG01000019_gene1635 1.94e-292 803.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9Z4@91061|Bacilli 91061|Bacilli G Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate celF - 3.2.1.86 ko:K01222 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT4 - Glyco_hydro_4,Glyco_hydro_4C gnl|extdb|FAM24227-i1-1.1_001320 1175629.AJTG01000019_gene1636 3.94e-148 424.0 COG1737@1|root,COG1737@2|Bacteria,1TUHQ@1239|Firmicutes,4HBMU@91061|Bacilli 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS gnl|extdb|FAM24227-i1-1.1_001321 1449335.JQLG01000004_gene655 3.61e-136 393.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli,27F8U@186828|Carnobacteriaceae 91061|Bacilli GK ROK family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK gnl|extdb|FAM24227-i1-1.1_001322 565664.EFXG_02022 1.25e-137 399.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,4AZSH@81852|Enterococcaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI gnl|extdb|FAM24227-i1-1.1_001323 1220589.CD32_10040 9.56e-136 395.0 COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,3IWIK@400634|Lysinibacillus 91061|Bacilli C Quinone oxidoreductase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N gnl|extdb|FAM24227-i1-1.1_001324 1123230.ARQJ01000019_gene1524 9.02e-66 214.0 COG5607@1|root,COG5607@2|Bacteria,1V8VW@1239|Firmicutes,4HIYS@91061|Bacilli,4H0DJ@90964|Staphylococcaceae 91061|Bacilli S CHAD - - - - - - - - - - - - CHAD gnl|extdb|FAM24227-i1-1.1_001326 1175629.AJTG01000005_gene751 2.64e-34 120.0 2DEV6@1|root,2ZPD4@2|Bacteria,1UEJT@1239|Firmicutes,4I05Y@91061|Bacilli,27F1Q@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 gnl|extdb|FAM24227-i1-1.1_001327 883103.HMPREF9703_00146 1.7e-193 548.0 COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,4HCMG@91061|Bacilli,27FCM@186828|Carnobacteriaceae 91061|Bacilli E Amidinotransferase arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf gnl|extdb|FAM24227-i1-1.1_001328 411463.EUBVEN_02270 3.49e-31 112.0 COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,25ZWZ@186806|Eubacteriaceae 186801|Clostridia S Branched-chain amino acid transport protein (AzlD) - - - - - - - - - - - - AzlD gnl|extdb|FAM24227-i1-1.1_001330 655812.HMPREF0061_0101 4.53e-127 378.0 COG0624@1|root,COG0624@2|Bacteria,1TPSM@1239|Firmicutes,4HD69@91061|Bacilli 91061|Bacilli E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases cpg2 - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 gnl|extdb|FAM24227-i1-1.1_001331 1121871.AUAT01000006_gene1538 2.29e-172 504.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,27DNE@186827|Aerococcaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_001332 866775.HMPREF9243_1162 6.48e-202 572.0 COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli 91061|Bacilli EG COG2610 H gluconate symporter and related permeases XK27_05475 - - - - - - - - - - - GntP_permease gnl|extdb|FAM24227-i1-1.1_001333 873447.SPB_2105 5.37e-166 486.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli 91061|Bacilli IQ Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C gnl|extdb|FAM24227-i1-1.1_001334 873447.SPB_2104 0.0 900.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TQ89@1239|Firmicutes,4IU6J@91061|Bacilli 91061|Bacilli I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - 3HCDH,3HCDH_N,ECH_1,ECH_2 gnl|extdb|FAM24227-i1-1.1_001335 1408438.JADD01000010_gene1906 1.07e-255 706.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HCSP@91061|Bacilli,27EC3@186827|Aerococcaceae 91061|Bacilli I Thiolase, C-terminal domain thlA - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N gnl|extdb|FAM24227-i1-1.1_001336 218495.SUB1805 1.2e-240 667.0 COG1960@1|root,COG1960@2|Bacteria,1TR1Y@1239|Firmicutes,4HBTJ@91061|Bacilli 91061|Bacilli C Acyl-CoA dehydrogenase, C-terminal domain protein gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N gnl|extdb|FAM24227-i1-1.1_001337 866775.HMPREF9243_1161 6.49e-306 842.0 COG4670@1|root,COG4670@2|Bacteria,1TP5H@1239|Firmicutes,4IS4T@91061|Bacilli,27E9U@186827|Aerococcaceae 91061|Bacilli I Belongs to the 3-oxoacid CoA-transferase family pct - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans gnl|extdb|FAM24227-i1-1.1_001338 873447.SPB_2101 1.78e-150 429.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli 91061|Bacilli I Dehydrogenase hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N gnl|extdb|FAM24227-i1-1.1_001339 218495.SUB1800 1.13e-145 450.0 COG2203@1|root,COG2508@1|root,COG2203@2|Bacteria,COG2508@2|Bacteria,1W7AW@1239|Firmicutes,4HRJA@91061|Bacilli 91061|Bacilli QT PucR C-terminal helix-turn-helix domain - - - - - - - - - - - - HTH_30 gnl|extdb|FAM24227-i1-1.1_001340 649747.HMPREF0083_00678 2.8e-85 254.0 COG4815@1|root,COG4815@2|Bacteria,1V2XM@1239|Firmicutes,4HGM4@91061|Bacilli,275KU@186822|Paenibacillaceae 91061|Bacilli S MepB protein - - - - - - - - - - - - MepB gnl|extdb|FAM24227-i1-1.1_001303 1449343.JQLQ01000002_gene382 8.73e-195 554.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,4HB69@91061|Bacilli 91061|Bacilli C 4-hydroxybutyrate CoA-transferase - - - ko:K18122 ko00650,ko01100,ko01200,map00650,map01100,map01200 - R05336 RC00012,RC00014 ko00000,ko00001,ko01000 - - - AcetylCoA_hyd_C,AcetylCoA_hydro gnl|extdb|FAM24227-i1-1.1_001305 1121871.AUAT01000012_gene606 1.03e-131 381.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli 91061|Bacilli I Dehydrogenase hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N gnl|extdb|FAM24227-i1-1.1_001308 1449343.JQLQ01000002_gene377 9.33e-122 357.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,27GBQ@186828|Carnobacteriaceae 91061|Bacilli K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate gnl|extdb|FAM24227-i1-1.1_001329 1235799.C818_01882 4.07e-54 180.0 COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,27JI9@186928|unclassified Lachnospiraceae 186801|Clostridia E AzlC protein - - - - - - - - - - - - AzlC gnl|extdb|FAM24227-i1-1.1_001342 1123309.AQYB01000033_gene1348 5.5e-140 405.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein sagG - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 gnl|extdb|FAM24227-i1-1.1_001343 1347392.CCEZ01000008_gene2238 5.15e-58 197.0 COG0842@1|root,COG0842@2|Bacteria,1TR76@1239|Firmicutes,24A0F@186801|Clostridia,36IM6@31979|Clostridiaceae 186801|Clostridia V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 gnl|extdb|FAM24227-i1-1.1_001344 1461582.BN1048_02108 2.29e-49 177.0 COG0842@1|root,COG0842@2|Bacteria,1UYEY@1239|Firmicutes,4HP8K@91061|Bacilli,4H0G1@90964|Staphylococcaceae 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 gnl|extdb|FAM24227-i1-1.1_001345 1121024.AUCD01000056_gene1070 7.86e-18 89.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,27GZD@186828|Carnobacteriaceae 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD gnl|extdb|FAM24227-i1-1.1_001346 706433.HMPREF9430_00825 3.65e-167 484.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,3VP73@526524|Erysipelotrichia 526524|Erysipelotrichia C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim gnl|extdb|FAM24227-i1-1.1_001347 655812.HMPREF0061_0920 9.76e-273 752.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli,27EBN@186827|Aerococcaceae 91061|Bacilli S Uncharacterised ACR (DUF711) XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 gnl|extdb|FAM24227-i1-1.1_001348 655812.HMPREF0061_0921 6.94e-36 123.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli,27EWZ@186827|Aerococcaceae 91061|Bacilli T ACT domain XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 gnl|extdb|FAM24227-i1-1.1_001349 1453500.AT05_00330 1.58e-36 128.0 COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1I2YH@117743|Flavobacteriia 976|Bacteroidetes J endoribonuclease L-PSP yjgF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP gnl|extdb|FAM24227-i1-1.1_001350 1408438.JADD01000028_gene954 6.61e-226 629.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,27DJ4@186827|Aerococcaceae 91061|Bacilli H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase gnl|extdb|FAM24227-i1-1.1_001351 883112.HMPREF9707_01280 2.58e-74 228.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,27E0E@186827|Aerococcaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran gnl|extdb|FAM24227-i1-1.1_001353 1122128.AUEE01000008_gene1804 2.77e-71 222.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HH7K@91061|Bacilli,4H1CQ@90964|Staphylococcaceae 91061|Bacilli T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg gnl|extdb|FAM24227-i1-1.1_001354 1087448.Eab7_1312 4.64e-52 167.0 COG0346@1|root,COG0346@2|Bacteria,1V7V5@1239|Firmicutes,4HJ9K@91061|Bacilli 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_001356 1408438.JADD01000028_gene951 2.18e-233 650.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,27DC6@186827|Aerococcaceae 91061|Bacilli L MgsA AAA+ ATPase C terminal rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N gnl|extdb|FAM24227-i1-1.1_001357 908337.HMPREF9257_1306 3.62e-151 439.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,27DM8@186827|Aerococcaceae 91061|Bacilli E Aminotransferase, class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 gnl|extdb|FAM24227-i1-1.1_001358 592010.GCWU000182_000273 1.07e-50 162.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli,27E8E@186827|Aerococcaceae 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 gnl|extdb|FAM24227-i1-1.1_001359 908337.HMPREF9257_1304 9.35e-227 629.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,27DFA@186827|Aerococcaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans gnl|extdb|FAM24227-i1-1.1_001360 1121024.AUCD01000023_gene708 2.61e-55 187.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,27FZ4@186828|Carnobacteriaceae 91061|Bacilli E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 gnl|extdb|FAM24227-i1-1.1_001361 1408438.JADD01000028_gene947 0.0 920.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,27DIB@186827|Aerococcaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 gnl|extdb|FAM24227-i1-1.1_001362 1449335.JQLG01000004_gene810 1.72e-205 582.0 COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,4HANC@91061|Bacilli,27FGU@186828|Carnobacteriaceae 91061|Bacilli E Pyridoxal-phosphate dependent enzyme dsdA - 4.3.1.18 ko:K01753 ko00260,map00260 - R00221 RC02600 ko00000,ko00001,ko01000 - - - PALP gnl|extdb|FAM24227-i1-1.1_001363 1408438.JADD01000028_gene946 4.12e-89 276.0 COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,4HJ8D@91061|Bacilli 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - - - - - - - - - - DAGK_cat gnl|extdb|FAM24227-i1-1.1_001364 592010.GCWU000182_000154 1.33e-87 268.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HFSN@91061|Bacilli,27DUB@186827|Aerococcaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 gnl|extdb|FAM24227-i1-1.1_001365 1408438.JADD01000028_gene944 0.0 1285.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,27DC4@186827|Aerococcaceae 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD gnl|extdb|FAM24227-i1-1.1_001366 1408438.JADD01000028_gene943 5.08e-49 156.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,27E4H@186827|Aerococcaceae 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 gnl|extdb|FAM24227-i1-1.1_001367 1408438.JADD01000028_gene942 1.5e-67 208.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,27DY2@186827|Aerococcaceae 91061|Bacilli L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX gnl|extdb|FAM24227-i1-1.1_001368 1121871.AUAT01000001_gene837 9.72e-42 139.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,27E2G@186827|Aerococcaceae 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 gnl|extdb|FAM24227-i1-1.1_001369 1408438.JADD01000028_gene940 9.58e-171 490.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,27DNV@186827|Aerococcaceae 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG gnl|extdb|FAM24227-i1-1.1_001370 1121871.AUAT01000001_gene835 1e-104 307.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,27DXZ@186827|Aerococcaceae 91061|Bacilli F Phosphoribulokinase / Uridine kinase family udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK gnl|extdb|FAM24227-i1-1.1_001371 1408438.JADD01000028_gene938 1.42e-92 272.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,27DUQ@186827|Aerococcaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N gnl|extdb|FAM24227-i1-1.1_001372 1121871.AUAT01000001_gene833 2.06e-63 205.0 COG4758@1|root,COG4758@2|Bacteria,1TUJF@1239|Firmicutes,4HIHB@91061|Bacilli,27DZK@186827|Aerococcaceae 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF - - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 gnl|extdb|FAM24227-i1-1.1_001373 592010.GCWU000182_000141 7.12e-119 354.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,27DDW@186827|Aerococcaceae 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 gnl|extdb|FAM24227-i1-1.1_001374 1121871.AUAT01000001_gene831 4.29e-109 318.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,27DMS@186827|Aerococcaceae 91061|Bacilli K helix_turn_helix, Lux Regulon vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg gnl|extdb|FAM24227-i1-1.1_001375 1408438.JADD01000028_gene934 4.94e-34 120.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,27E7U@186827|Aerococcaceae 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn gnl|extdb|FAM24227-i1-1.1_001376 1449338.JQLU01000005_gene3272 2.06e-257 736.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,27H8B@186828|Carnobacteriaceae 91061|Bacilli L Viral (Superfamily 1) RNA helicase - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C_2 gnl|extdb|FAM24227-i1-1.1_001377 1408438.JADD01000028_gene933 3.46e-167 475.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,27DPB@186827|Aerococcaceae 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC gnl|extdb|FAM24227-i1-1.1_001378 1408438.JADD01000028_gene932 7.48e-194 551.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,27EWK@186827|Aerococcaceae 91061|Bacilli E Pyridoxal-dependent decarboxylase, pyridoxal binding domain lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC gnl|extdb|FAM24227-i1-1.1_001379 1408438.JADD01000028_gene931 1.43e-145 417.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,27E93@186827|Aerococcaceae 91061|Bacilli EM Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS gnl|extdb|FAM24227-i1-1.1_001380 1408438.JADD01000028_gene930 6.97e-96 288.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N gnl|extdb|FAM24227-i1-1.1_001385 908337.HMPREF9257_1479 0.0 1159.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,27DKN@186827|Aerococcaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A gnl|extdb|FAM24227-i1-1.1_001386 1449343.JQLQ01000002_gene317 1.73e-146 419.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,27FBC@186828|Carnobacteriaceae 91061|Bacilli EM Substrate binding domain of ABC-type glycine betaine transport system proWX - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC gnl|extdb|FAM24227-i1-1.1_001388 1449343.JQLQ01000002_gene319 7.99e-134 384.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,27FTJ@186828|Carnobacteriaceae 91061|Bacilli E Domain in cystathionine beta-synthase and other proteins. proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS gnl|extdb|FAM24227-i1-1.1_001389 1449343.JQLQ01000002_gene320 4.42e-89 268.0 COG1174@1|root,COG1174@2|Bacteria,1UHWH@1239|Firmicutes,4HJIP@91061|Bacilli 91061|Bacilli P ABC transporter, permease protein - - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001390 883112.HMPREF9707_01427 6.8e-114 336.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,27DQG@186827|Aerococcaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS gnl|extdb|FAM24227-i1-1.1_001391 1408438.JADD01000002_gene308 7.13e-59 190.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,27DZI@186827|Aerococcaceae 91061|Bacilli H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE gnl|extdb|FAM24227-i1-1.1_001392 1121871.AUAT01000002_gene1471 3.19e-72 221.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,27DZM@186827|Aerococcaceae 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone gnl|extdb|FAM24227-i1-1.1_001393 908337.HMPREF9257_1474 6.04e-69 234.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,27E1X@186827|Aerococcaceae 91061|Bacilli L Replication initiation and membrane attachment protein, DnaB DnaD family dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 gnl|extdb|FAM24227-i1-1.1_001394 1408438.JADD01000002_gene305 4.55e-115 341.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,27DCG@186827|Aerococcaceae 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 gnl|extdb|FAM24227-i1-1.1_001396 1121871.AUAT01000002_gene1467 0.0 1098.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,27DFV@186827|Aerococcaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD gnl|extdb|FAM24227-i1-1.1_001397 1122143.AUEG01000005_gene1386 7.66e-45 149.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,27GJX@186828|Carnobacteriaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 gnl|extdb|FAM24227-i1-1.1_001399 883113.HMPREF9708_00941 5e-94 284.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,27ENH@186827|Aerococcaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 gnl|extdb|FAM24227-i1-1.1_001400 883113.HMPREF9708_00940 9.56e-77 237.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,27EEP@186827|Aerococcaceae 91061|Bacilli S ATPases associated with a variety of cellular activities ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001401 1122143.AUEG01000003_gene1000 2.14e-91 268.0 COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,4HH1K@91061|Bacilli,27GDJ@186828|Carnobacteriaceae 91061|Bacilli G Cupin domain yrkC - - - - - - - - - - - Cupin_2 gnl|extdb|FAM24227-i1-1.1_001403 1140003.I573_02116 1.17e-50 164.0 2CBZ2@1|root,32RUD@2|Bacteria,1VB2C@1239|Firmicutes,4HQTR@91061|Bacilli,4B3CH@81852|Enterococcaceae 91061|Bacilli S Protein of unknown function (DUF2871) - - - - - - - - - - - - DUF2871 gnl|extdb|FAM24227-i1-1.1_001404 1139996.OMQ_02433 1.71e-56 184.0 COG1309@1|root,COG1309@2|Bacteria,1VHYR@1239|Firmicutes,4HR0P@91061|Bacilli,4B2SH@81852|Enterococcaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N gnl|extdb|FAM24227-i1-1.1_001405 1175629.AJTG01000028_gene206 1.92e-187 530.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,27EJW@186827|Aerococcaceae 91061|Bacilli C Alanine dehydrogenase/PNT, N-terminal domain ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N gnl|extdb|FAM24227-i1-1.1_001406 655812.HMPREF0061_1369 1.68e-76 239.0 COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4HCA1@91061|Bacilli 91061|Bacilli S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 gnl|extdb|FAM24227-i1-1.1_001408 1196028.ALEF01000025_gene1694 1.2e-137 396.0 2CFXT@1|root,2ZAIF@2|Bacteria,1UZMK@1239|Firmicutes,4HDP0@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - Adenyl_transf,NTP_transf_2 gnl|extdb|FAM24227-i1-1.1_001410 278197.PEPE_0540 3.54e-34 129.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family sip - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase gnl|extdb|FAM24227-i1-1.1_001411 1121024.AUCD01000089_gene1023 6.34e-30 109.0 2EHWH@1|root,33BN3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001412 1185653.A1A1_09831 3.28e-16 72.8 COG2608@1|root,COG2608@2|Bacteria,1VFJ8@1239|Firmicutes,4HNY2@91061|Bacilli,26HY0@186818|Planococcaceae 91061|Bacilli C Heavy-metal-associated domain copZ - - - - - - - - - - - HMA gnl|extdb|FAM24227-i1-1.1_001415 1302863.I872_00425 6.03e-257 782.0 COG5635@1|root,COG5635@2|Bacteria,1TR89@1239|Firmicutes,4HW38@91061|Bacilli 91061|Bacilli T Nacht domain - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001417 877418.ATWV01000006_gene2047 3.45e-05 46.6 COG1002@1|root,COG1002@2|Bacteria,2J80D@203691|Spirochaetes 203691|Spirochaetes V Type II restriction enzyme, methylase subunits - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001418 1266845.Q783_04070 9.97e-247 697.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,27FUX@186828|Carnobacteriaceae 91061|Bacilli S Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG gnl|extdb|FAM24227-i1-1.1_001419 883112.HMPREF9707_01133 4.22e-47 153.0 COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,4HKDQ@91061|Bacilli 91061|Bacilli S Nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG-like gnl|extdb|FAM24227-i1-1.1_001421 1158609.I586_01852 7.63e-44 159.0 COG1061@1|root,COG1061@2|Bacteria,1U2DR@1239|Firmicutes,4HBX2@91061|Bacilli,4AZW6@81852|Enterococcaceae 91061|Bacilli KL DEAD-like helicases superfamily - - - - - - - - - - - - Eco57I,ResIII,T5orf172 gnl|extdb|FAM24227-i1-1.1_001381 883112.HMPREF9707_01422 4.16e-180 510.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli 91061|Bacilli G COG1363 Cellulase M and related proteins pepA - 3.4.11.7 ko:K01261,ko:K01269 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M42 gnl|extdb|FAM24227-i1-1.1_001382 908337.HMPREF9257_1482 1.79e-89 268.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli,27E00@186827|Aerococcaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind gnl|extdb|FAM24227-i1-1.1_001384 1408438.JADD01000002_gene311 3.53e-243 677.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,27DD8@186827|Aerococcaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M gnl|extdb|FAM24227-i1-1.1_001387 1449343.JQLQ01000002_gene318 2.41e-98 292.0 COG1174@1|root,COG1174@2|Bacteria,1TSX8@1239|Firmicutes,4HC1D@91061|Bacilli,27G2X@186828|Carnobacteriaceae 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001409 1158609.I586_00043 1.12e-20 90.1 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,4AZB3@81852|Enterococcaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase gnl|extdb|FAM24227-i1-1.1_001424 883112.HMPREF9707_00263 2.32e-312 878.0 COG1181@1|root,COG2918@1|root,COG1181@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,27DKU@186827|Aerococcaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshF - 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ATP-grasp_3,Dala_Dala_lig_C,GARS_A,Glu_cys_ligase gnl|extdb|FAM24227-i1-1.1_001426 883112.HMPREF9707_00262 1.72e-207 577.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,27DMX@186827|Aerococcaceae 91061|Bacilli H lipoate-protein ligase lplL - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C gnl|extdb|FAM24227-i1-1.1_001427 883112.HMPREF9707_00261 1.11e-204 572.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,27DZ2@186827|Aerococcaceae 91061|Bacilli G M42 glutamyl aminopeptidase ysdC - - - - - - - - - - - Peptidase_M42 gnl|extdb|FAM24227-i1-1.1_001428 1121024.AUCD01000022_gene910 4.55e-142 412.0 COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HBKZ@91061|Bacilli,27F8V@186828|Carnobacteriaceae 91061|Bacilli C Zinc-binding dehydrogenase qor - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 gnl|extdb|FAM24227-i1-1.1_001429 908337.HMPREF9257_0441 1.17e-234 655.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,27DFZ@186827|Aerococcaceae 91061|Bacilli C NADH oxidase noxE - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim gnl|extdb|FAM24227-i1-1.1_001430 908337.HMPREF9257_0459 3.53e-100 311.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,27DYG@186827|Aerococcaceae 91061|Bacilli U Bacterial ABC transporter protein EcsB ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB gnl|extdb|FAM24227-i1-1.1_001431 883113.HMPREF9708_00524 6.35e-115 336.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,27DGV@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001432 592010.GCWU000182_000786 5.78e-154 447.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,27DSY@186827|Aerococcaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein gnl|extdb|FAM24227-i1-1.1_001433 1121871.AUAT01000021_gene46 7.34e-12 75.9 COG3064@1|root,COG3064@2|Bacteria,1VP31@1239|Firmicutes,4HSGB@91061|Bacilli,27F13@186827|Aerococcaceae 91061|Bacilli M LPXTG cell wall anchor motif - - - - - - - - - - - - Gram_pos_anchor gnl|extdb|FAM24227-i1-1.1_001435 1158601.I585_04074 1.05e-14 77.0 COG3212@1|root,COG3212@2|Bacteria,1VBVH@1239|Firmicutes,4HNEY@91061|Bacilli,4B2K5@81852|Enterococcaceae 91061|Bacilli S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY gnl|extdb|FAM24227-i1-1.1_001436 477641.MODMU_3017 5.87e-23 99.4 COG1263@1|root,COG1263@2|Bacteria,2I5AF@201174|Actinobacteria 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001437 866775.HMPREF9243_0789 1.94e-08 63.9 COG3861@1|root,COG3861@2|Bacteria,1V5RZ@1239|Firmicutes,4HHAU@91061|Bacilli 91061|Bacilli S Heat induced stress protein YflT - - - - - - - - - - - - DUF2382,YflT gnl|extdb|FAM24227-i1-1.1_001438 1408438.JADD01000035_gene459 1.16e-104 316.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,27DUP@186827|Aerococcaceae 91061|Bacilli S ABC transporter substrate binding protein XK27_00670 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind gnl|extdb|FAM24227-i1-1.1_001439 1123302.KB904186_gene721 3.2e-117 346.0 COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases ytnP - - - - - - - - - - - Lactamase_B gnl|extdb|FAM24227-i1-1.1_001440 883112.HMPREF9707_00257 8.31e-71 219.0 COG4708@1|root,COG4708@2|Bacteria,1V22G@1239|Firmicutes,4HGG2@91061|Bacilli,27E21@186827|Aerococcaceae 91061|Bacilli S QueT transporter ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - QueT gnl|extdb|FAM24227-i1-1.1_001441 1002809.SSIL_3166 9.5e-46 155.0 COG1309@1|root,COG1309@2|Bacteria,1V1R2@1239|Firmicutes,4HFW2@91061|Bacilli,26EVM@186818|Planococcaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_8,TetR_N gnl|extdb|FAM24227-i1-1.1_001442 1121024.AUCD01000042_gene242 2.06e-135 390.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HACK@91061|Bacilli,27FZG@186828|Carnobacteriaceae 91061|Bacilli S Aldo/keto reductase family dkgB - - - - - - - - - - - Aldo_ket_red gnl|extdb|FAM24227-i1-1.1_001443 1123318.KB904587_gene589 1.43e-70 217.0 COG1487@1|root,COG1487@2|Bacteria,1VJCX@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF4411) - - - - - - - - - - - - DUF4411 gnl|extdb|FAM24227-i1-1.1_001444 1167632.AJTR01000007_gene848 2.53e-140 410.0 COG2856@1|root,COG2856@2|Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - HTH_3,Peptidase_M78 gnl|extdb|FAM24227-i1-1.1_001445 883112.HMPREF9707_00252 1.08e-101 299.0 COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,4HC4A@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane ntpD - - ko:K02120 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_D gnl|extdb|FAM24227-i1-1.1_001446 883112.HMPREF9707_00251 1.14e-283 781.0 COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,4HBJN@91061|Bacilli,27EF9@186827|Aerococcaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit ntpB - - ko:K02118 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_ab,ATP-synt_ab_N gnl|extdb|FAM24227-i1-1.1_001447 883112.HMPREF9707_00250 0.0 898.0 COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,4HBND@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit ntpA - 3.6.3.14,3.6.3.15 ko:K02117 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002,ko01000 3.A.2.2,3.A.2.3 - - ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn gnl|extdb|FAM24227-i1-1.1_001448 883112.HMPREF9707_00249 2.53e-43 143.0 COG1436@1|root,COG1436@2|Bacteria,1VAX7@1239|Firmicutes,4HMU4@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane ntpG - - ko:K02122 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_F gnl|extdb|FAM24227-i1-1.1_001449 883112.HMPREF9707_00248 3.78e-111 333.0 COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,4HD5K@91061|Bacilli 91061|Bacilli C subunit C ntpC - - ko:K02119 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - vATP-synt_AC39 gnl|extdb|FAM24227-i1-1.1_001450 883112.HMPREF9707_00247 2.3e-26 106.0 COG1390@1|root,COG1390@2|Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpE - - ko:K02121 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - vATP-synt_E gnl|extdb|FAM24227-i1-1.1_001451 883112.HMPREF9707_00246 4.01e-66 205.0 COG0636@1|root,COG0636@2|Bacteria,1V786@1239|Firmicutes,4HJAB@91061|Bacilli,27DZX@186827|Aerococcaceae 91061|Bacilli C ATP synthase subunit C - - - - - - - - - - - - ATP-synt_C gnl|extdb|FAM24227-i1-1.1_001452 883112.HMPREF9707_00245 1.19e-206 601.0 COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,4HDJH@91061|Bacilli,27DKV@186827|Aerococcaceae 91061|Bacilli C Belongs to the V-ATPase 116 kDa subunit family ntpI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02123 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - V_ATPase_I gnl|extdb|FAM24227-i1-1.1_001454 1266845.Q783_09980 2.24e-29 111.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_001455 908337.HMPREF9257_0849 3.23e-111 327.0 COG1737@1|root,COG1737@2|Bacteria,1V8RC@1239|Firmicutes,4HK5Y@91061|Bacilli 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS gnl|extdb|FAM24227-i1-1.1_001456 908337.HMPREF9257_0848 0.0 900.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,27EJX@186827|Aerococcaceae 91061|Bacilli G PTS system malX - 2.7.1.199,2.7.1.208 ko:K02790,ko:K02791,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00809 R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.3,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001458 1123304.AQYA01000031_gene2195 0.000219 43.1 COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,4HGX3@91061|Bacilli 91061|Bacilli K helix_turn_helix, arabinose operon control protein rhaR - - - - - - - - - - - AraC_binding,HTH_18 gnl|extdb|FAM24227-i1-1.1_001459 208596.CAR_c23600 2.38e-22 95.5 COG1457@1|root,COG1457@2|Bacteria,1VTCF@1239|Firmicutes,4HTY0@91061|Bacilli 91061|Bacilli F Belongs to the purine-cytosine permease (2.A.39) family - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001460 1449343.JQLQ01000002_gene164 1.65e-43 143.0 COG3254@1|root,COG3254@2|Bacteria,1VA1C@1239|Firmicutes,4HM5P@91061|Bacilli 91061|Bacilli G Involved in the anomeric conversion of L-rhamnose rhaM - 5.1.3.32 ko:K03534 - - R10819 RC00563 ko00000,ko01000 - - - rhaM gnl|extdb|FAM24227-i1-1.1_001462 1175629.AJTG01000005_gene690 1.36e-226 630.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,27EAN@186827|Aerococcaceae 91061|Bacilli C Malic enzyme, NAD binding domain - - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic gnl|extdb|FAM24227-i1-1.1_001463 1123318.KB904587_gene576 6.49e-95 285.0 COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,4HDMG@91061|Bacilli 91061|Bacilli E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate aroD GO:0003674,GO:0003824,GO:0003855,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I gnl|extdb|FAM24227-i1-1.1_001464 945021.TEH_05010 2.2e-213 595.0 COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,4HB6X@91061|Bacilli 91061|Bacilli C Belongs to the LDH2 MDH2 oxidoreductase family mdh - - - - - - - - - - - Ldh_2 gnl|extdb|FAM24227-i1-1.1_001465 1000588.HMPREF9965_1526 1.77e-26 100.0 2E660@1|root,330UP@2|Bacteria,1VFJD@1239|Firmicutes,4IEE7@91061|Bacilli,2TQ30@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001466 936154.STP_0718 1.85e-31 115.0 2E59Z@1|root,33028@2|Bacteria,1VFMU@1239|Firmicutes,4HQG9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001467 1123315.AUIP01000012_gene2035 4.46e-235 659.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH gnl|extdb|FAM24227-i1-1.1_001468 1552123.EP57_06560 1.18e-35 130.0 COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli 91061|Bacilli L DNA polymerase III polC_2 - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - BRCT,RNase_T gnl|extdb|FAM24227-i1-1.1_001469 1123311.KB904456_gene738 1.86e-39 141.0 COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HJDU@91061|Bacilli 91061|Bacilli S SNARE-like domain protein yjbF - - - - - - - - - - - SNARE_assoc gnl|extdb|FAM24227-i1-1.1_001471 663952.SDD27957_01140 4.04e-37 129.0 COG4043@1|root,COG4043@2|Bacteria,1VEJD@1239|Firmicutes,4HNU5@91061|Bacilli,1M9QN@119603|Streptococcus dysgalactiae group 91061|Bacilli S ASCH nudA - - - - - - - - - - - ASCH gnl|extdb|FAM24227-i1-1.1_001472 742765.HMPREF9457_02236 6.78e-126 365.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,27UR1@189330|Dorea 186801|Clostridia H Carbohydrate kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin gnl|extdb|FAM24227-i1-1.1_001473 457412.RSAG_02014 1.75e-83 253.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3WIVU@541000|Ruminococcaceae 186801|Clostridia H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI gnl|extdb|FAM24227-i1-1.1_001474 1007096.BAGW01000010_gene2223 9.23e-62 202.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,2N6DR@216572|Oscillospiraceae 186801|Clostridia H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK,TMP-TENI gnl|extdb|FAM24227-i1-1.1_001475 1007096.BAGW01000010_gene2222 7.55e-60 191.0 COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,2N781@216572|Oscillospiraceae 186801|Clostridia S Thiamine-precursor transporter protein (ThiW) thiW - - - - - - - - - - - ThiW gnl|extdb|FAM24227-i1-1.1_001476 1408438.JADD01000020_gene1479 3.09e-58 203.0 COG1388@1|root,COG1388@2|Bacteria,1V61Q@1239|Firmicutes,4HHT0@91061|Bacilli,27DYS@186827|Aerococcaceae 91061|Bacilli M LysM domain protein sip - - - - - - - - - - - LysM gnl|extdb|FAM24227-i1-1.1_001477 1175629.AJTG01000028_gene240 1.61e-85 257.0 COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,4HI24@91061|Bacilli,27EN2@186827|Aerococcaceae 91061|Bacilli P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp gnl|extdb|FAM24227-i1-1.1_001478 1175629.AJTG01000028_gene239 5.47e-90 268.0 COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,4HH2P@91061|Bacilli,27ENE@186827|Aerococcaceae 91061|Bacilli P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp gnl|extdb|FAM24227-i1-1.1_001479 883113.HMPREF9708_01435 2.44e-135 394.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,27DQU@186827|Aerococcaceae 91061|Bacilli GK ROK family glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK gnl|extdb|FAM24227-i1-1.1_001481 866775.HMPREF9243_1819 3.36e-117 346.0 COG2421@1|root,COG2421@2|Bacteria,1TQ67@1239|Firmicutes,4HA9D@91061|Bacilli 91061|Bacilli C Acetamidase formamidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - FmdA_AmdA gnl|extdb|FAM24227-i1-1.1_001482 1216932.CM240_1051 2.23e-109 345.0 28MBK@1|root,2ZAQ1@2|Bacteria,1TSWC@1239|Firmicutes,24A3B@186801|Clostridia,36J10@31979|Clostridiaceae 186801|Clostridia M Arylsulfotransferase Ig-like domain - - 2.8.2.22 ko:K01023 - - - - ko00000,ko01000 - - - Arylsulfotran_N,Arylsulfotrans gnl|extdb|FAM24227-i1-1.1_001483 1175629.AJTG01000002_gene1278 3.93e-95 280.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,27EWV@186827|Aerococcaceae 91061|Bacilli Q Isochorismatase family pncA - - - - - - - - - - - Isochorismatase gnl|extdb|FAM24227-i1-1.1_001484 1243664.CAVL020000054_gene3116 1.27e-39 147.0 COG1396@1|root,COG1396@2|Bacteria,1UM3W@1239|Firmicutes,4IUHF@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 gnl|extdb|FAM24227-i1-1.1_001485 984892.SPSE_1806 8.02e-10 72.0 COG3087@1|root,COG4932@1|root,COG3087@2|Bacteria,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,4GYDE@90964|Staphylococcaceae 91061|Bacilli M C-terminus of bacterial fibrinogen-binding adhesin - - - ko:K14194 ko05150,map05150 - - - ko00000,ko00001 - - - Collagen,Collagen_bind,Gram_pos_anchor,SdrD_B,SdrG_C_C,YSIRK_signal gnl|extdb|FAM24227-i1-1.1_001486 1123359.AUIQ01000067_gene1817 2.33e-114 336.0 COG0656@1|root,COG0656@2|Bacteria,1TPWT@1239|Firmicutes,4HCQY@91061|Bacilli,4B11D@81852|Enterococcaceae 91061|Bacilli S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red gnl|extdb|FAM24227-i1-1.1_001487 883110.HMPREF9260_00752 6.05e-189 544.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli,27DF8@186827|Aerococcaceae 91061|Bacilli J Amidase nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase gnl|extdb|FAM24227-i1-1.1_001489 883112.HMPREF9707_00017 6.09e-86 259.0 COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HJDU@91061|Bacilli,27DVP@186827|Aerococcaceae 91061|Bacilli S SNARE associated Golgi protein yjbF - - - - - - - - - - - SNARE_assoc gnl|extdb|FAM24227-i1-1.1_001491 1266845.Q783_09980 4.79e-66 207.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_001457 908337.HMPREF9257_0847 2.56e-220 615.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,27ENT@186827|Aerococcaceae 91061|Bacilli E Aminotransferase class I and II malY - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_001488 1121871.AUAT01000028_gene1242 1.52e-148 430.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,27DQ1@186827|Aerococcaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain - - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 gnl|extdb|FAM24227-i1-1.1_001490 1201292.DR75_881 4.01e-36 124.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,4B3DU@81852|Enterococcaceae 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic gnl|extdb|FAM24227-i1-1.1_001492 1121333.JMLH01000058_gene1725 7.56e-13 68.6 2DNNA@1|root,32Y8E@2|Bacteria,1UKCJ@1239|Firmicutes,3VUTA@526524|Erysipelotrichia 526524|Erysipelotrichia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001494 1123290.AUDQ01000032_gene3012 1.43e-109 321.0 COG0491@1|root,COG0491@2|Bacteria,1TSWY@1239|Firmicutes,4HE91@91061|Bacilli 91061|Bacilli S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B gnl|extdb|FAM24227-i1-1.1_001495 1121024.AUCD01000087_gene1045 8.63e-24 103.0 COG2062@1|root,COG5607@1|root,COG2062@2|Bacteria,COG5607@2|Bacteria,1U4WX@1239|Firmicutes,4IFE0@91061|Bacilli,27HFX@186828|Carnobacteriaceae 91061|Bacilli T Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 gnl|extdb|FAM24227-i1-1.1_001496 1175629.AJTG01000002_gene1246 2.22e-65 204.0 2F5ZF@1|root,33YHY@2|Bacteria,1VWUQ@1239|Firmicutes,4HXES@91061|Bacilli,27ESR@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001497 655812.HMPREF0061_0993 0.0 1224.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,27DTE@186827|Aerococcaceae 91061|Bacilli P potassium sodium efflux P-type ATPase, fungal-type - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase gnl|extdb|FAM24227-i1-1.1_001499 1121024.AUCD01000093_gene363 1.79e-315 881.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,27FFJ@186828|Carnobacteriaceae 91061|Bacilli P E1-E2 ATPase copB - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase gnl|extdb|FAM24227-i1-1.1_001500 35841.BT1A1_3006 1.78e-19 94.4 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD gnl|extdb|FAM24227-i1-1.1_001501 1175629.AJTG01000025_gene346 4.99e-81 245.0 COG3803@1|root,COG3803@2|Bacteria,1V3Y2@1239|Firmicutes,4HH81@91061|Bacilli 91061|Bacilli S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 gnl|extdb|FAM24227-i1-1.1_001502 883113.HMPREF9708_00775 9.46e-49 161.0 COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,4HJ82@91061|Bacilli,27E3M@186827|Aerococcaceae 91061|Bacilli S LURP-one-related yxjI - - - - - - - - - - - LOR gnl|extdb|FAM24227-i1-1.1_001503 1408438.JADD01000005_gene1196 4.04e-74 229.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,27E0M@186827|Aerococcaceae 91061|Bacilli U Belongs to the peptidase S26 family sipS - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 gnl|extdb|FAM24227-i1-1.1_001504 1122143.AUEG01000003_gene1032 1.41e-184 536.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,27FJA@186828|Carnobacteriaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_001505 1294142.CINTURNW_3519 1.27e-132 386.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36DBU@31979|Clostridiaceae 186801|Clostridia P Permease oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001506 1122143.AUEG01000003_gene1030 1.49e-152 439.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,27FGX@186828|Carnobacteriaceae 91061|Bacilli EP N-terminal TM domain of oligopeptide transport permease C oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N gnl|extdb|FAM24227-i1-1.1_001507 1298920.KI911353_gene774 4.72e-182 515.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,21YP2@1506553|Lachnoclostridium 186801|Clostridia P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_001508 1504823.CCMM01000007_gene510 5.78e-151 432.0 COG4608@1|root,COG4608@2|Bacteria,2NQIJ@2323|unclassified Bacteria 2|Bacteria E Oligopeptide/dipeptide transporter, C-terminal region oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_001509 883112.HMPREF9707_01111 1.61e-287 792.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,27DSN@186827|Aerococcaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b gnl|extdb|FAM24227-i1-1.1_001510 1121024.AUCD01000026_gene809 2.94e-24 98.6 COG0407@1|root,COG0407@2|Bacteria,1U2YV@1239|Firmicutes,4IEG7@91061|Bacilli,27HNQ@186828|Carnobacteriaceae 91061|Bacilli H Uroporphyrinogen decarboxylase (URO-D) - - - - - - - - - - - - URO-D gnl|extdb|FAM24227-i1-1.1_001511 866775.HMPREF9243_0668 6.64e-96 287.0 COG0834@1|root,COG0834@2|Bacteria,1UX4B@1239|Firmicutes,4HM91@91061|Bacilli 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins - - - ko:K16956,ko:K16957 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_001512 866775.HMPREF9243_0668 2.34e-05 47.4 COG0834@1|root,COG0834@2|Bacteria,1UX4B@1239|Firmicutes,4HM91@91061|Bacilli 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins - - - ko:K16956,ko:K16957 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_001513 866775.HMPREF9243_0667 2.94e-109 322.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein - - - ko:K16960 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.13 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001514 1158601.I585_00804 1.88e-149 454.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1UWY7@1239|Firmicutes,4I2VI@91061|Bacilli,4B1M0@81852|Enterococcaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - HTH_11,PRD,PTS_EIIA_2,PTS_IIB gnl|extdb|FAM24227-i1-1.1_001515 1408438.JADD01000010_gene1855 6.02e-46 154.0 COG1762@1|root,COG1762@2|Bacteria,1VBF9@1239|Firmicutes,4IQJM@91061|Bacilli 91061|Bacilli GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - PTS_EIIA_2 gnl|extdb|FAM24227-i1-1.1_001516 1408438.JADD01000010_gene1856 4.15e-45 148.0 COG1445@1|root,COG1445@2|Bacteria,1VASC@1239|Firmicutes,4HKYF@91061|Bacilli 91061|Bacilli G iib component frwB - 2.7.1.202 ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_IIB gnl|extdb|FAM24227-i1-1.1_001517 1158609.I586_03012 3.67e-209 583.0 COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,4I3KE@91061|Bacilli,4B156@81852|Enterococcaceae 91061|Bacilli U Phosphotransferase system, EIIC - - - - - - - - - - - - PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001518 1408438.JADD01000010_gene1858 6.19e-247 684.0 COG4573@1|root,COG4573@2|Bacteria,1TT0W@1239|Firmicutes,4HEEB@91061|Bacilli 91061|Bacilli G Tagatose 6 phosphate kinase - - - - - - - - - - - - Tagatose_6_P_K gnl|extdb|FAM24227-i1-1.1_001519 1408438.JADD01000010_gene1919 7.81e-64 205.0 COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,4HHZ7@91061|Bacilli 91061|Bacilli S hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 gnl|extdb|FAM24227-i1-1.1_001520 1408438.JADD01000010_gene1853 7.23e-99 300.0 COG0205@1|root,COG0205@2|Bacteria,1VRYX@1239|Firmicutes,4HUT2@91061|Bacilli,27EAU@186827|Aerococcaceae 91061|Bacilli G Phosphofructokinase - - - - - - - - - - - - PFK gnl|extdb|FAM24227-i1-1.1_001521 1408438.JADD01000010_gene1859 0.0 1013.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,27DC9@186827|Aerococcaceae 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N gnl|extdb|FAM24227-i1-1.1_001522 565655.ECBG_02896 5.21e-119 352.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4H9SS@91061|Bacilli,4B15Z@81852|Enterococcaceae 91061|Bacilli K Putative sugar-binding domain deoR_2 - - - - - - - - - - - HTH_24,Sigma70_r4,Sugar-bind gnl|extdb|FAM24227-i1-1.1_001523 908337.HMPREF9257_0040 9.08e-104 313.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4H9SS@91061|Bacilli,27EJT@186827|Aerococcaceae 91061|Bacilli K Putative sugar-binding domain deoR_2 - - - - - - - - - - - HTH_24,Sigma70_r4,Sugar-bind gnl|extdb|FAM24227-i1-1.1_001498 1449337.JQLL01000001_gene1778 3.47e-45 151.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli,27GP5@186828|Carnobacteriaceae 91061|Bacilli K Penicillinase repressor copY - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R gnl|extdb|FAM24227-i1-1.1_001524 1408438.JADD01000005_gene1208 1.37e-118 343.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,27DK7@186827|Aerococcaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N gnl|extdb|FAM24227-i1-1.1_001525 883112.HMPREF9707_01119 2.58e-40 134.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 gnl|extdb|FAM24227-i1-1.1_001526 592010.GCWU000182_000538 3.52e-304 839.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,27DCJ@186827|Aerococcaceae 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 gnl|extdb|FAM24227-i1-1.1_001528 945021.TEH_22380 6.21e-73 221.0 COG5015@1|root,COG5015@2|Bacteria,1TR2Q@1239|Firmicutes,4HHXT@91061|Bacilli 91061|Bacilli C Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx gnl|extdb|FAM24227-i1-1.1_001529 1139996.OMQ_00418 4.53e-66 205.0 COG4807@1|root,COG4807@2|Bacteria,1V4DA@1239|Firmicutes,4HH2A@91061|Bacilli,4AZQK@81852|Enterococcaceae 91061|Bacilli S Protein of unknown function (DUF1456) - - - - - - - - - - - - DUF1456 gnl|extdb|FAM24227-i1-1.1_001530 1449342.JQMR01000001_gene1325 2.74e-123 362.0 COG0564@1|root,COG0564@2|Bacteria,1TSPG@1239|Firmicutes,4HBGS@91061|Bacilli,27G45@186828|Carnobacteriaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA - 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2,S4_2 gnl|extdb|FAM24227-i1-1.1_001532 903814.ELI_3766 0.0002 44.7 COG0551@1|root,COG0551@2|Bacteria,1V93W@1239|Firmicutes,24CEN@186801|Clostridia,25Z2E@186806|Eubacteriaceae 186801|Clostridia L Nuclease-related domain - - - - - - - - - - - - NERD,zf-C4_Topoisom gnl|extdb|FAM24227-i1-1.1_001533 1408438.JADD01000014_gene585 2.36e-293 805.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,27DRQ@186827|Aerococcaceae 91061|Bacilli O Uncharacterized protein family (UPF0051) sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 gnl|extdb|FAM24227-i1-1.1_001534 1408438.JADD01000014_gene586 6.28e-54 175.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,27E3G@186827|Aerococcaceae 91061|Bacilli C NifU-like N terminal domain nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N gnl|extdb|FAM24227-i1-1.1_001535 1408438.JADD01000014_gene587 9.86e-184 524.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,27EI0@186827|Aerococcaceae 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 gnl|extdb|FAM24227-i1-1.1_001537 1408438.JADD01000014_gene589 1.17e-154 437.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,27DGD@186827|Aerococcaceae 91061|Bacilli O ATPases associated with a variety of cellular activities sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001540 1408438.JADD01000024_gene1284 1.08e-88 271.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,27DWN@186827|Aerococcaceae 91061|Bacilli K Cell envelope-related transcriptional attenuator domain brpA - - - - - - - - - - - LytR_cpsA_psr gnl|extdb|FAM24227-i1-1.1_001542 655812.HMPREF0061_0453 8.16e-79 244.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,27ER0@186827|Aerococcaceae 91061|Bacilli M Chain length determinant protein epsB - - - - - - - - - - - GNVR,Wzz gnl|extdb|FAM24227-i1-1.1_001543 655812.HMPREF0061_0452 4.43e-104 308.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,27EP2@186827|Aerococcaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA gnl|extdb|FAM24227-i1-1.1_001544 1408438.JADD01000012_gene1647 1.29e-83 258.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,27E3T@186827|Aerococcaceae 91061|Bacilli GM Capsular polysaccharide biosynthesis protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - gnl|extdb|FAM24227-i1-1.1_001545 655812.HMPREF0061_1831 4.65e-117 338.0 COG2148@1|root,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,4HAF1@91061|Bacilli,27EXS@186827|Aerococcaceae 91061|Bacilli M Bacterial sugar transferase capM - - ko:K13012 - - - - ko00000,ko01005 - - - Bac_transf gnl|extdb|FAM24227-i1-1.1_001546 1121324.CLIT_14c01200 2e-104 312.0 COG1215@1|root,COG1215@2|Bacteria,1V1CB@1239|Firmicutes,24EMU@186801|Clostridia 186801|Clostridia M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2 gnl|extdb|FAM24227-i1-1.1_001547 272558.10176337 1.01e-70 228.0 COG1216@1|root,COG1216@2|Bacteria,1V7WV@1239|Firmicutes,4HJ3H@91061|Bacilli,1ZIZF@1386|Bacillus 91061|Bacilli S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 gnl|extdb|FAM24227-i1-1.1_001548 536227.CcarbDRAFT_3651 4e-76 247.0 COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,36IK4@31979|Clostridiaceae 186801|Clostridia M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_001549 866775.HMPREF9243_0865 1.93e-58 202.0 2F20H@1|root,33UZN@2|Bacteria,1VV5C@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001550 545694.TREPR_0203 3.12e-49 174.0 COG1216@1|root,COG1216@2|Bacteria,2J8ZQ@203691|Spirochaetes 203691|Spirochaetes S PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 gnl|extdb|FAM24227-i1-1.1_001551 655811.HMPREF0078_1425 2.3e-136 410.0 COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia,22IDJ@1570339|Peptoniphilaceae 186801|Clostridia S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Polysacc_synt_C gnl|extdb|FAM24227-i1-1.1_001552 886377.Murru_1366 8.92e-09 58.5 COG1045@1|root,COG1045@2|Bacteria,4NRQU@976|Bacteroidetes,1IMH2@117743|Flavobacteriia 976|Bacteroidetes E Hexapeptide repeat of succinyl-transferase - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep gnl|extdb|FAM24227-i1-1.1_001553 1499683.CCFF01000017_gene2777 2.1e-186 525.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,36UJ5@31979|Clostridiaceae 186801|Clostridia M NAD-dependent epimerase dehydratase lspL - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd gnl|extdb|FAM24227-i1-1.1_001554 1229520.ADIAL_1214 1.04e-191 542.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,27FXT@186828|Carnobacteriaceae 91061|Bacilli M UDP binding domain ugd GO:0003674,GO:0003824,GO:0003979,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N gnl|extdb|FAM24227-i1-1.1_001555 1139996.OMQ_00489 1.64e-171 483.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,4B017@81852|Enterococcaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase gnl|extdb|FAM24227-i1-1.1_001536 1408438.JADD01000014_gene588 5.68e-154 448.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,27DTD@186827|Aerococcaceae 91061|Bacilli O Uncharacterized protein family (UPF0051) sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 gnl|extdb|FAM24227-i1-1.1_001541 1005704.HMPREF9968_2014 6.67e-226 646.0 COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4HAER@91061|Bacilli,1WPG8@1303|Streptococcus oralis 91061|Bacilli GM CoA-binding domain capD - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 gnl|extdb|FAM24227-i1-1.1_001557 883112.HMPREF9707_01492 3.43e-147 429.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,27DM9@186827|Aerococcaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 gnl|extdb|FAM24227-i1-1.1_001558 883113.HMPREF9708_00429 7.68e-94 293.0 COG3307@1|root,COG3307@2|Bacteria,1V4W4@1239|Firmicutes,4HGXV@91061|Bacilli,27E6A@186827|Aerococcaceae 91061|Bacilli M O-Antigen ligase - - - - - - - - - - - - Wzy_C gnl|extdb|FAM24227-i1-1.1_001559 1121871.AUAT01000002_gene1428 2.82e-95 280.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,27DDZ@186827|Aerococcaceae 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N gnl|extdb|FAM24227-i1-1.1_001560 592010.GCWU000182_001719 1.39e-32 113.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,27E7I@186827|Aerococcaceae 91061|Bacilli J Ribosomal protein L35 rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p gnl|extdb|FAM24227-i1-1.1_001561 883110.HMPREF9260_00780 1.96e-63 195.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,27E1M@186827|Aerococcaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 gnl|extdb|FAM24227-i1-1.1_001562 908337.HMPREF9257_1429 1.27e-298 828.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,27DBW@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein msbA_1 - - ko:K18887 ko02010,map02010 M00706 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_001563 908337.HMPREF9257_1428 7.38e-285 794.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27DMW@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein lmrA - - ko:K06147,ko:K18888 ko02010,map02010 M00706 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_001564 1408438.JADD01000003_gene163 6.17e-86 266.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,27ENK@186827|Aerococcaceae 91061|Bacilli E Prephenate dehydratase pheA - - - - - - - - - - - CM_2,PDT gnl|extdb|FAM24227-i1-1.1_001565 1408438.JADD01000003_gene164 1.04e-98 298.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,27EGP@186827|Aerococcaceae 91061|Bacilli E Prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH gnl|extdb|FAM24227-i1-1.1_001566 1154860.SAG0136_09560 2.65e-105 318.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli 91061|Bacilli S Transporter yocS - - ko:K03453 - - - - ko00000 2.A.28 - iYO844.BSU19350 SBF gnl|extdb|FAM24227-i1-1.1_001567 883112.HMPREF9707_01498 6.43e-73 228.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,27E1Q@186827|Aerococcaceae 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 gnl|extdb|FAM24227-i1-1.1_001568 764291.STRUR_1077 3.96e-22 95.9 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli 91061|Bacilli S Adenylate cyclase yjbK - - - - - - - - - - - CYTH gnl|extdb|FAM24227-i1-1.1_001570 908337.HMPREF9257_1425 8.9e-108 320.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,27DVC@186827|Aerococcaceae 91061|Bacilli H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase gnl|extdb|FAM24227-i1-1.1_001571 883112.HMPREF9707_01501 2.1e-40 143.0 2DWA8@1|root,33Z9M@2|Bacteria,1VXSY@1239|Firmicutes,4HXS8@91061|Bacilli,27EUS@186827|Aerococcaceae 91061|Bacilli S Thioredoxin - - - - - - - - - - - - Thioredoxin gnl|extdb|FAM24227-i1-1.1_001572 1121871.AUAT01000002_gene1420 1.56e-125 367.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,27DJA@186827|Aerococcaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 gnl|extdb|FAM24227-i1-1.1_001573 908337.HMPREF9257_1423 1.4e-224 630.0 COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4HASP@91061|Bacilli,27DDD@186827|Aerococcaceae 91061|Bacilli P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N gnl|extdb|FAM24227-i1-1.1_001574 1449342.JQMR01000001_gene863 3.16e-39 136.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,27GEM@186828|Carnobacteriaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 gnl|extdb|FAM24227-i1-1.1_001575 883112.HMPREF9707_01503 3.01e-182 515.0 COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,4HBDK@91061|Bacilli,27DFW@186827|Aerococcaceae 91061|Bacilli G M42 glutamyl aminopeptidase yhfE - - - - - - - - - - - Peptidase_M42 gnl|extdb|FAM24227-i1-1.1_001576 908337.HMPREF9257_1422 1.22e-27 111.0 2CE84@1|root,342DW@2|Bacteria,1VY91@1239|Firmicutes,4HWUZ@91061|Bacilli,27EU4@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - DivIVA gnl|extdb|FAM24227-i1-1.1_001577 592010.GCWU000182_001099 0.0 880.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,27DF5@186827|Aerococcaceae 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C gnl|extdb|FAM24227-i1-1.1_001578 1408438.JADD01000002_gene287 6.65e-48 154.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,27E2A@186827|Aerococcaceae 91061|Bacilli G phosphocarrier protein HPr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr gnl|extdb|FAM24227-i1-1.1_001579 1408438.JADD01000002_gene286 0.0 884.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,27DH4@186827|Aerococcaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C gnl|extdb|FAM24227-i1-1.1_001580 592010.GCWU000182_000919 9.62e-97 296.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,27DVM@186827|Aerococcaceae 91061|Bacilli HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 gnl|extdb|FAM24227-i1-1.1_001581 1118057.CAGX01000005_gene619 7.86e-39 137.0 COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia 186801|Clostridia S BioY family bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY gnl|extdb|FAM24227-i1-1.1_001582 883112.HMPREF9707_01507 1.13e-176 504.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,27DTB@186827|Aerococcaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_001583 883112.HMPREF9707_01508 6.76e-29 105.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,27E8D@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1797) ykuJ - - - - - - - - - - - DUF1797 gnl|extdb|FAM24227-i1-1.1_001584 1408438.JADD01000002_gene282 3.16e-82 247.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,27E1K@186827|Aerococcaceae 91061|Bacilli S HAD-hyrolase-like yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase gnl|extdb|FAM24227-i1-1.1_001585 883112.HMPREF9707_01510 1.52e-170 487.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,27DG2@186827|Aerococcaceae 91061|Bacilli S Ribosome biogenesis GTPase YqeH yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 gnl|extdb|FAM24227-i1-1.1_001586 883112.HMPREF9707_01511 1.15e-37 129.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,27E6E@186827|Aerococcaceae 91061|Bacilli J CRS1_YhbY yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY gnl|extdb|FAM24227-i1-1.1_001588 883112.HMPREF9707_01513 9.44e-56 182.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,27E1F@186827|Aerococcaceae 91061|Bacilli H Hydrolase, HD family yqeK - - - - - - - - - - - HD gnl|extdb|FAM24227-i1-1.1_001590 1408438.JADD01000002_gene276 1.43e-89 272.0 COG2227@1|root,COG2227@2|Bacteria,1V218@1239|Firmicutes,4ISKI@91061|Bacilli,27DWQ@186827|Aerococcaceae 91061|Bacilli H Methyltransferase domain protein - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 gnl|extdb|FAM24227-i1-1.1_001591 883113.HMPREF9708_00400 2.08e-100 310.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,27DUI@186827|Aerococcaceae 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 gnl|extdb|FAM24227-i1-1.1_001592 1408438.JADD01000002_gene274 1.45e-64 203.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,27E74@186827|Aerococcaceae 91061|Bacilli S Uncharacterized ACR, COG1399 ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 gnl|extdb|FAM24227-i1-1.1_001593 1449335.JQLG01000004_gene1883 7.4e-28 101.0 COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,27GR9@186828|Carnobacteriaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0003674,GO:0003735,GO:0005198 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p gnl|extdb|FAM24227-i1-1.1_001569 883112.HMPREF9707_01499 4.39e-119 345.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,27DP9@186827|Aerococcaceae 91061|Bacilli S RelA SpoT domain protein yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT gnl|extdb|FAM24227-i1-1.1_001587 908337.HMPREF9257_1407 4.53e-118 342.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,27E05@186827|Aerococcaceae 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like gnl|extdb|FAM24227-i1-1.1_001589 1408438.JADD01000002_gene277 1.08e-50 163.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,27E3V@186827|Aerococcaceae 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS gnl|extdb|FAM24227-i1-1.1_001594 883112.HMPREF9707_01146 1.57e-106 335.0 COG1388@1|root,COG1388@2|Bacteria,1UKE7@1239|Firmicutes,4ITHJ@91061|Bacilli 91061|Bacilli M Lysin motif - - 3.5.1.28 ko:K22409 - - - - ko00000,ko01000 - CBM50 - CHAP,LysM gnl|extdb|FAM24227-i1-1.1_001595 883112.HMPREF9707_01145 5.91e-31 116.0 COG0791@1|root,COG0791@2|Bacteria 2|Bacteria M cysteine-type peptidase activity K - 3.5.1.28 ko:K01449,ko:K21471 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01002,ko01011 - - - CHAP,NLPC_P60,Prok-JAB gnl|extdb|FAM24227-i1-1.1_001597 1408438.JADD01000012_gene1677 3.46e-142 409.0 COG1210@1|root,COG1210@2|Bacteria,1VSF8@1239|Firmicutes,4HV61@91061|Bacilli,27EEZ@186827|Aerococcaceae 91061|Bacilli M MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transferase gnl|extdb|FAM24227-i1-1.1_001598 1408438.JADD01000012_gene1675 7.36e-241 671.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,27EEN@186827|Aerococcaceae 91061|Bacilli M UDP binding domain - - - ko:K02474 ko00520,map00520 - R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N gnl|extdb|FAM24227-i1-1.1_001599 866775.HMPREF9243_0789 1.25e-32 130.0 COG3861@1|root,COG3861@2|Bacteria,1V5RZ@1239|Firmicutes,4HHAU@91061|Bacilli 91061|Bacilli S Heat induced stress protein YflT - - - - - - - - - - - - DUF2382,YflT gnl|extdb|FAM24227-i1-1.1_001600 655812.HMPREF0061_0015 5.61e-45 149.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,4HIMF@91061|Bacilli,27E7F@186827|Aerococcaceae 91061|Bacilli S Domain of unknown function (DUF956) manO - - - - - - - - - - - DUF956 gnl|extdb|FAM24227-i1-1.1_001601 655812.HMPREF0061_0014 1.32e-155 444.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,27DT2@186827|Aerococcaceae 91061|Bacilli G PTS system, mannose fructose sorbose family, IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA gnl|extdb|FAM24227-i1-1.1_001602 1175629.AJTG01000003_gene899 8.29e-117 342.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,27DUV@186827|Aerococcaceae 91061|Bacilli G PTS system sorbose-specific iic component manM - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor gnl|extdb|FAM24227-i1-1.1_001603 655812.HMPREF0061_0012 1.08e-155 446.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,27DG1@186827|Aerococcaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb gnl|extdb|FAM24227-i1-1.1_001604 388919.SSA_0383 5.93e-293 805.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,1WRC2@1305|Streptococcus sanguinis 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 gnl|extdb|FAM24227-i1-1.1_001605 1175629.AJTG01000028_gene227 9.09e-130 376.0 COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,4HDIH@91061|Bacilli 91061|Bacilli G hydrolase hmpP2 - - - - - - - - - - - Hydrolase_3 gnl|extdb|FAM24227-i1-1.1_001606 1179226.AJXO01000022_gene984 9.59e-73 224.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HM06@91061|Bacilli,4GYT5@90964|Staphylococcaceae 91061|Bacilli G Belongs to the phosphoglycerate mutase family gpmB - - - - - - - - - - - His_Phos_1 gnl|extdb|FAM24227-i1-1.1_001607 1449343.JQLQ01000002_gene280 2.39e-314 860.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,27FFY@186828|Carnobacteriaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family ascB - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 gnl|extdb|FAM24227-i1-1.1_001608 1198676.SMUGS5_04330 1.91e-243 694.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system bglP - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001609 1123298.KB904079_gene542 4.15e-99 298.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli 91061|Bacilli K antiterminator licT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD gnl|extdb|FAM24227-i1-1.1_001613 1232449.BAHV02000010_gene2626 2.82e-08 57.0 2DMWN@1|root,32U4R@2|Bacteria,1VCQG@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 gnl|extdb|FAM24227-i1-1.1_001614 904294.HMPREF9182_1629 1.44e-40 137.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli 91061|Bacilli G Phosphotransferase system cellobiose-specific component IIA - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA gnl|extdb|FAM24227-i1-1.1_001615 1123299.AUKZ01000004_gene348 3.02e-37 128.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli 91061|Bacilli G Phosphotransferase system cellobiose-specific component IIB licB_1 - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB gnl|extdb|FAM24227-i1-1.1_001616 1123306.KB904339_gene283 3.46e-146 447.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli 91061|Bacilli G transcriptional antiterminator - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB gnl|extdb|FAM24227-i1-1.1_001617 1123309.AQYB01000028_gene743 3.16e-269 744.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family gmuD - 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 gnl|extdb|FAM24227-i1-1.1_001618 883112.HMPREF9707_01361 0.0 970.0 COG1263@1|root,COG2190@1|root,COG1263@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,27DE3@186827|Aerococcaceae 91061|Bacilli G phosphotransferase system, EIIB - - 2.7.1.199 ko:K02777,ko:K02778,ko:K02779,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806,M00809 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.13,4.A.1.1.14,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001619 1041826.FCOL_05095 3.65e-07 59.7 COG1835@1|root,COG1835@2|Bacteria,4NUXQ@976|Bacteroidetes,1I5SN@117743|Flavobacteriia,2NVNW@237|Flavobacterium 976|Bacteroidetes I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 gnl|extdb|FAM24227-i1-1.1_001620 1449343.JQLQ01000002_gene1004 5.43e-49 164.0 COG1434@1|root,COG1434@2|Bacteria,1VI4S@1239|Firmicutes,4HNKM@91061|Bacilli 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 gnl|extdb|FAM24227-i1-1.1_001621 1408438.JADD01000002_gene324 8.09e-87 261.0 COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,4HCBK@91061|Bacilli,27DWU@186827|Aerococcaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yebE - - - - - - - - - - - DUF2179 gnl|extdb|FAM24227-i1-1.1_001622 435837.HMPREF0798_01196 3.4e-127 370.0 COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,4GXT7@90964|Staphylococcaceae 91061|Bacilli G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin gnl|extdb|FAM24227-i1-1.1_001611 996306.SSUR61_0331 1.76e-219 618.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,1WT58@1307|Streptococcus suis 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001623 1121871.AUAT01000005_gene1744 1.96e-86 267.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,27EBC@186827|Aerococcaceae 91061|Bacilli P NLPA lipoprotein metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_001624 1408438.JADD01000016_gene731 5.44e-89 265.0 COG0431@1|root,COG0431@2|Bacteria,1V2V7@1239|Firmicutes,4HFMV@91061|Bacilli,27EQW@186827|Aerococcaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - ko:K19784 - - - - ko00000 - - - FMN_red gnl|extdb|FAM24227-i1-1.1_001625 1408438.JADD01000003_gene225 0.0 2018.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,27DSV@186827|Aerococcaceae 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon gnl|extdb|FAM24227-i1-1.1_001626 1121871.AUAT01000009_gene968 1.16e-161 469.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,27DHX@186827|Aerococcaceae 91061|Bacilli M Peptidase family M50 rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 gnl|extdb|FAM24227-i1-1.1_001627 1121871.AUAT01000009_gene967 4.03e-96 290.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,27DTY@186827|Aerococcaceae 91061|Bacilli S Cytidylyltransferase family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 gnl|extdb|FAM24227-i1-1.1_001628 592010.GCWU000182_001377 2.17e-108 319.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,27DQF@186827|Aerococcaceae 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf gnl|extdb|FAM24227-i1-1.1_001629 883112.HMPREF9707_00509 6.49e-90 268.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,27DWY@186827|Aerococcaceae 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF gnl|extdb|FAM24227-i1-1.1_001630 1408438.JADD01000003_gene220 1.33e-142 405.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,27DQ6@186827|Aerococcaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase gnl|extdb|FAM24227-i1-1.1_001631 1408438.JADD01000003_gene219 2.47e-149 427.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,27DDI@186827|Aerococcaceae 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS gnl|extdb|FAM24227-i1-1.1_001632 883112.HMPREF9707_00506 7.73e-151 428.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,27DI7@186827|Aerococcaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 gnl|extdb|FAM24227-i1-1.1_001634 1408438.JADD01000009_gene1759 5.24e-160 457.0 COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4HAIX@91061|Bacilli,27DIU@186827|Aerococcaceae 91061|Bacilli S SigmaW regulon antibacterial yqfA - - - - - - - - - - - YdfA_immunity gnl|extdb|FAM24227-i1-1.1_001635 883113.HMPREF9708_01356 7.5e-29 113.0 COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,27E96@186827|Aerococcaceae 91061|Bacilli O NfeD-like C-terminal, partner-binding yqeZ - - ko:K07403 - - - - ko00000 - - - NfeD,SDH_sah gnl|extdb|FAM24227-i1-1.1_001636 698758.AXY_13120 4.57e-123 368.0 COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,4HGFS@91061|Bacilli 91061|Bacilli S hmm pf01594 XK27_12525 - - - - - - - - - - - AI-2E_transport gnl|extdb|FAM24227-i1-1.1_001637 1121871.AUAT01000009_gene956 0.0 1220.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,27DN1@186827|Aerococcaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N gnl|extdb|FAM24227-i1-1.1_001638 1121024.AUCD01000030_gene1295 1.13e-91 273.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,27G5N@186828|Carnobacteriaceae 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran gnl|extdb|FAM24227-i1-1.1_001639 386043.lwe1925 5.73e-72 218.0 COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,4HH64@91061|Bacilli,26KH2@186820|Listeriaceae 91061|Bacilli H methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - - MGS gnl|extdb|FAM24227-i1-1.1_001640 1449343.JQLQ01000002_gene2304 2.29e-78 237.0 COG0693@1|root,COG0693@2|Bacteria,1V3I7@1239|Firmicutes,4HFNG@91061|Bacilli,27G87@186828|Carnobacteriaceae 91061|Bacilli S DJ-1/PfpI family yfkM - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI gnl|extdb|FAM24227-i1-1.1_001642 1123304.AQYA01000029_gene1618 8.61e-127 369.0 COG2819@1|root,COG2819@2|Bacteria,1UZZZ@1239|Firmicutes,4HCWE@91061|Bacilli 91061|Bacilli S Putative esterase XK27_05670 - - ko:K07017 - - - - ko00000 - - - Esterase gnl|extdb|FAM24227-i1-1.1_001643 1117379.BABA_25101 4.28e-277 783.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family - - - - - - - - - - - - Glyco_hydro_3,Glyco_hydro_3_C gnl|extdb|FAM24227-i1-1.1_001644 1121871.AUAT01000009_gene954 3.53e-48 169.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,27E8S@186827|Aerococcaceae 91061|Bacilli S Dienelactone hydrolase family yitV - - ko:K06889 - - - - ko00000 - - - Hydrolase_4,Peptidase_S9 gnl|extdb|FAM24227-i1-1.1_001645 908337.HMPREF9257_1747 4.97e-128 371.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,27DUR@186827|Aerococcaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 gnl|extdb|FAM24227-i1-1.1_001648 883112.HMPREF9707_00501 5.2e-66 204.0 2BYUE@1|root,333XD@2|Bacteria,1VGGT@1239|Firmicutes,4HHWB@91061|Bacilli,27F54@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001649 350688.Clos_2303 9.86e-125 369.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,36E0G@31979|Clostridiaceae 186801|Clostridia S membrane - - - - - - - - - - - - Cons_hypoth698 gnl|extdb|FAM24227-i1-1.1_001650 1449337.JQLL01000001_gene1016 6.92e-13 63.9 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_001646 1408438.JADD01000011_gene1597 1.21e-180 513.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27DIN@186827|Aerococcaceae 91061|Bacilli E Receptor family ligand-binding protein livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 gnl|extdb|FAM24227-i1-1.1_001647 1121871.AUAT01000009_gene952 3.44e-108 323.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,27EAW@186827|Aerococcaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yitT - - - - - - - - - - - DUF2179,YitT_membrane gnl|extdb|FAM24227-i1-1.1_001651 1175629.AJTG01000028_gene238 1.73e-133 388.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,27EFY@186827|Aerococcaceae 91061|Bacilli C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase gnl|extdb|FAM24227-i1-1.1_001652 1449342.JQMR01000001_gene1050 1.37e-108 319.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,27FE0@186828|Carnobacteriaceae 91061|Bacilli K Transcriptional regulator yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg gnl|extdb|FAM24227-i1-1.1_001654 866775.HMPREF9243_1871 6.2e-75 231.0 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli,27E5H@186827|Aerococcaceae 91061|Bacilli S Nitroreductase family XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase gnl|extdb|FAM24227-i1-1.1_001655 226185.EF_0660 2.25e-127 383.0 COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,4IPM0@91061|Bacilli,4B0Q8@81852|Enterococcaceae 91061|Bacilli V MatE - - - - - - - - - - - - MatE gnl|extdb|FAM24227-i1-1.1_001656 1273538.G159_14145 9.45e-105 317.0 COG0657@1|root,COG0657@2|Bacteria,1TRYT@1239|Firmicutes,4HC3I@91061|Bacilli,26F97@186818|Planococcaceae 91061|Bacilli I Carboxylesterase family - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 gnl|extdb|FAM24227-i1-1.1_001657 1127131.WEISSC39_00975 5.5e-19 78.2 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 gnl|extdb|FAM24227-i1-1.1_001658 525318.HMPREF0497_0204 1.62e-44 145.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 gnl|extdb|FAM24227-i1-1.1_001659 1158607.UAU_00874 1.13e-06 46.2 2DF5N@1|root,2ZQJZ@2|Bacteria,1VNTI@1239|Firmicutes,4HS3C@91061|Bacilli,4B4CG@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001660 1229520.ADIAL_1071 3.81e-122 367.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,27G7H@186828|Carnobacteriaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA3 - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA gnl|extdb|FAM24227-i1-1.1_001661 586416.GZ22_04110 1.21e-117 348.0 COG3443@1|root,COG3443@2|Bacteria,1UI6E@1239|Firmicutes,4ISFG@91061|Bacilli 91061|Bacilli S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment zinT - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - Strep_his_triad,ZinT gnl|extdb|FAM24227-i1-1.1_001662 997346.HMPREF9374_3743 1.59e-48 165.0 COG1309@1|root,COG1309@2|Bacteria,1V3XC@1239|Firmicutes,4HFHH@91061|Bacilli,27DB4@186824|Thermoactinomycetaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N gnl|extdb|FAM24227-i1-1.1_001663 935836.JAEL01000019_gene888 5.25e-139 401.0 COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,1ZCRG@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component ybhF_1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 gnl|extdb|FAM24227-i1-1.1_001664 1449343.JQLQ01000002_gene2087 1.26e-181 528.0 COG3559@1|root,COG3559@2|Bacteria,1TPIG@1239|Firmicutes,4H9SK@91061|Bacilli,27FQR@186828|Carnobacteriaceae 91061|Bacilli M Exporter of polyketide antibiotics - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - gnl|extdb|FAM24227-i1-1.1_001665 1121024.AUCD01000017_gene621 1.27e-71 238.0 COG0584@1|root,COG1434@1|root,COG0584@2|Bacteria,COG1434@2|Bacteria,1V404@1239|Firmicutes,4HJN8@91061|Bacilli,27GKP@186828|Carnobacteriaceae 91061|Bacilli C Domain of unknown function - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - DUF4996,GDPD gnl|extdb|FAM24227-i1-1.1_001666 1408438.JADD01000014_gene574 2.77e-110 335.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27DIN@186827|Aerococcaceae 91061|Bacilli E Receptor family ligand-binding protein livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 gnl|extdb|FAM24227-i1-1.1_001667 1408438.JADD01000014_gene576 1.58e-109 333.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27DIN@186827|Aerococcaceae 91061|Bacilli E Receptor family ligand-binding protein livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 gnl|extdb|FAM24227-i1-1.1_001669 1280692.AUJL01000010_gene3002 2.66e-94 289.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,2489D@186801|Clostridia,36FMI@31979|Clostridiaceae 186801|Clostridia E Alanine dehydrogenase/PNT, C-terminal domain ceo - 1.5.1.24 ko:K00298 - - - - ko00000,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N gnl|extdb|FAM24227-i1-1.1_001672 1449335.JQLG01000004_gene1736 4.82e-49 173.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,27GXN@186828|Carnobacteriaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA gnl|extdb|FAM24227-i1-1.1_001673 485918.Cpin_2100 8.93e-31 113.0 arCOG12631@1|root,3172B@2|Bacteria,4NQ4C@976|Bacteroidetes,1IZ65@117747|Sphingobacteriia 976|Bacteroidetes S Bacterial PH domain - - - - - - - - - - - - bPH_1 gnl|extdb|FAM24227-i1-1.1_001674 1121871.AUAT01000006_gene1572 1.7e-129 370.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,27DQS@186827|Aerococcaceae 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 gnl|extdb|FAM24227-i1-1.1_001675 764291.STRUR_0416 6.56e-126 369.0 COG3817@1|root,COG3817@2|Bacteria,1TQ17@1239|Firmicutes,4HAJT@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF979) - - - - - - - - - - - - DUF979 gnl|extdb|FAM24227-i1-1.1_001676 1054460.SPPN_04355 1.31e-88 268.0 COG3819@1|root,COG3819@2|Bacteria,1TT00@1239|Firmicutes,4HE38@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF969) - - - - - - - - - - - - DUF969 gnl|extdb|FAM24227-i1-1.1_001677 1321779.HMPREF1984_01845 1.38e-30 117.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_7 gnl|extdb|FAM24227-i1-1.1_001678 1408438.JADD01000016_gene699 8.6e-26 106.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,27EYG@186827|Aerococcaceae 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 gnl|extdb|FAM24227-i1-1.1_001679 1408438.JADD01000002_gene361 2.78e-86 278.0 COG0726@1|root,COG0726@2|Bacteria,1V0YE@1239|Firmicutes,4HFKC@91061|Bacilli 91061|Bacilli G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 gnl|extdb|FAM24227-i1-1.1_001680 883081.HMPREF9698_00454 2.37e-70 227.0 COG1597@1|root,COG1597@2|Bacteria,1TQ9A@1239|Firmicutes,4HCPU@91061|Bacilli,27G3M@186828|Carnobacteriaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat gnl|extdb|FAM24227-i1-1.1_001681 1408438.JADD01000008_gene1496 6.25e-183 520.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,27DFC@186827|Aerococcaceae 91061|Bacilli E Aminotransferase, class I II patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_001682 1408438.JADD01000008_gene1495 2.11e-180 511.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,27DPX@186827|Aerococcaceae 91061|Bacilli E Cys/Met metabolism PLP-dependent enzyme metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP gnl|extdb|FAM24227-i1-1.1_001683 1122128.AUEE01000003_gene635 9.13e-139 402.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,4GZ4D@90964|Staphylococcaceae 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metAA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS gnl|extdb|FAM24227-i1-1.1_001670 1449342.JQMR01000001_gene2253 4.23e-06 53.5 COG5578@1|root,COG5578@2|Bacteria,1TV84@1239|Firmicutes,4I49H@91061|Bacilli,27HI5@186828|Carnobacteriaceae 91061|Bacilli S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 gnl|extdb|FAM24227-i1-1.1_001684 1139996.OMQ_02420 9.15e-35 130.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,4B153@81852|Enterococcaceae 91061|Bacilli K LytTr DNA-binding domain - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg gnl|extdb|FAM24227-i1-1.1_001686 1408438.JADD01000027_gene905 7.51e-110 322.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,27DRG@186827|Aerococcaceae 91061|Bacilli J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB gnl|extdb|FAM24227-i1-1.1_001687 883112.HMPREF9707_00871 5.66e-145 412.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,27DP0@186827|Aerococcaceae 91061|Bacilli D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 gnl|extdb|FAM24227-i1-1.1_001688 1121871.AUAT01000005_gene1752 1.99e-141 407.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,27DR1@186827|Aerococcaceae 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc gnl|extdb|FAM24227-i1-1.1_001689 1408438.JADD01000027_gene902 3.82e-33 115.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,27E7A@186827|Aerococcaceae 91061|Bacilli S Bacterial protein of unknown function (DUF951) yyzM - - - - - - - - - - - DUF951 gnl|extdb|FAM24227-i1-1.1_001690 1408438.JADD01000027_gene901 8.49e-219 608.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,27DIF@186827|Aerococcaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C gnl|extdb|FAM24227-i1-1.1_001691 883112.HMPREF9707_00867 1.97e-69 222.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HH7B@91061|Bacilli,27F4N@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1129) - - - - - - - - - - - - DUF1129 gnl|extdb|FAM24227-i1-1.1_001692 1408438.JADD01000027_gene899 9.14e-296 814.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,27DNA@186827|Aerococcaceae 91061|Bacilli F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH gnl|extdb|FAM24227-i1-1.1_001693 768486.EHR_05900 2.14e-36 147.0 COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,4AZE2@81852|Enterococcaceae 91061|Bacilli MNU defense response to other organism acmA GO:0005575,GO:0005576 - ko:K02395,ko:K19220,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM gnl|extdb|FAM24227-i1-1.1_001694 883112.HMPREF9707_00866 2.19e-114 333.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,27DR9@186827|Aerococcaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal vanR - - - - - - - - - - - Response_reg,Trans_reg_C gnl|extdb|FAM24227-i1-1.1_001695 883112.HMPREF9707_00865 4.36e-137 403.0 COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,4HARU@91061|Bacilli,27DXE@186827|Aerococcaceae 91061|Bacilli T ATPase histidine kinase DNA gyrase B HSP90 domain protein hpk31 - - - - - - - - - - - HATPase_c,HisKA gnl|extdb|FAM24227-i1-1.1_001696 883112.HMPREF9707_00864 4.34e-124 374.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,27DUN@186827|Aerococcaceae 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 gnl|extdb|FAM24227-i1-1.1_001698 1121105.ATXL01000001_gene221 2.69e-80 242.0 COG1670@1|root,COG1670@2|Bacteria,1VC3X@1239|Firmicutes,4HKVZ@91061|Bacilli,4B4BC@81852|Enterococcaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3,Acetyltransf_4 gnl|extdb|FAM24227-i1-1.1_001699 1121024.AUCD01000029_gene1276 0.0 1193.0 COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,4HBA8@91061|Bacilli,27FW7@186828|Carnobacteriaceae 91061|Bacilli S Peptidase M16C associated - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C gnl|extdb|FAM24227-i1-1.1_001700 1449342.JQMR01000001_gene1193 1.02e-150 452.0 COG4907@1|root,COG4907@2|Bacteria,1TRFK@1239|Firmicutes,4HBX9@91061|Bacilli,27FYJ@186828|Carnobacteriaceae 91061|Bacilli S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 gnl|extdb|FAM24227-i1-1.1_001703 1449342.JQMR01000001_gene1681 1.12e-49 172.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,27FYE@186828|Carnobacteriaceae 91061|Bacilli L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase gnl|extdb|FAM24227-i1-1.1_001704 1140002.I570_00510 3.57e-18 90.1 COG1396@1|root,COG1396@2|Bacteria,1V40H@1239|Firmicutes,4IPSY@91061|Bacilli,4B6R2@81852|Enterococcaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20373 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 gnl|extdb|FAM24227-i1-1.1_001705 883103.HMPREF9703_00416 9.43e-115 357.0 COG1132@1|root,COG1132@2|Bacteria,1V08F@1239|Firmicutes 1239|Firmicutes V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_001706 1449338.JQLU01000001_gene966 2.01e-302 826.0 COG3385@1|root,COG3385@2|Bacteria,1TPH7@1239|Firmicutes,4HB3I@91061|Bacilli,27H8U@186828|Carnobacteriaceae 91061|Bacilli L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 gnl|extdb|FAM24227-i1-1.1_001707 545693.BMQ_1627 1.11e-110 325.0 COG2820@1|root,COG2820@2|Bacteria,1UYBX@1239|Firmicutes,4I34R@91061|Bacilli,1ZKEW@1386|Bacillus 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 gnl|extdb|FAM24227-i1-1.1_001708 1227360.C176_11933 8.94e-60 186.0 COG1917@1|root,COG1917@2|Bacteria,1V8DR@1239|Firmicutes,4HJ1Z@91061|Bacilli,26FJN@186818|Planococcaceae 91061|Bacilli S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 gnl|extdb|FAM24227-i1-1.1_001709 945021.TEH_01300 2.56e-167 484.0 COG3385@1|root,COG3385@2|Bacteria,1TPH7@1239|Firmicutes,4HB3I@91061|Bacilli,4B0MN@81852|Enterococcaceae 91061|Bacilli L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 gnl|extdb|FAM24227-i1-1.1_001712 655812.HMPREF0061_1917 3.32e-46 155.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli,27F00@186827|Aerococcaceae 91061|Bacilli L Integrase core domain - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_001685 1160707.AJIK01000006_gene1044 1.58e-44 150.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,26FDE@186818|Planococcaceae 91061|Bacilli L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated adaB GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,Methyltransf_1N gnl|extdb|FAM24227-i1-1.1_001697 908337.HMPREF9257_0757 5.82e-90 267.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,27DYE@186827|Aerococcaceae 91061|Bacilli C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR gnl|extdb|FAM24227-i1-1.1_001713 592010.GCWU000182_000252 5.67e-168 474.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,27DE9@186827|Aerococcaceae 91061|Bacilli M Nucleotidyl transferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase gnl|extdb|FAM24227-i1-1.1_001714 1408438.JADD01000003_gene130 1.7e-161 464.0 COG0438@1|root,COG0438@2|Bacteria,1TR2W@1239|Firmicutes,4HCY9@91061|Bacilli,27DGA@186827|Aerococcaceae 91061|Bacilli M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_001715 883113.HMPREF9708_00478 6.57e-09 55.5 28RTP@1|root,2ZE61@2|Bacteria,1W4J7@1239|Firmicutes,4HZUM@91061|Bacilli,27F0I@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001717 1408438.JADD01000003_gene133 2.09e-75 228.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,27E5C@186827|Aerococcaceae 91061|Bacilli C Flavodoxin fld - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 gnl|extdb|FAM24227-i1-1.1_001718 443254.Marpi_1263 6.54e-167 475.0 COG1087@1|root,COG1087@2|Bacteria,2GCQI@200918|Thermotogae 200918|Thermotogae M Belongs to the NAD(P)-dependent epimerase dehydratase family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd gnl|extdb|FAM24227-i1-1.1_001719 1230342.CTM_01090 0.000954 49.3 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,36FHF@31979|Clostridiaceae 186801|Clostridia K cell envelope-related function transcriptional attenuator lytR - - - - - - - - - - - LytR_C,LytR_cpsA_psr gnl|extdb|FAM24227-i1-1.1_001720 908337.HMPREF9257_1449 7.03e-129 388.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,27DPR@186827|Aerococcaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr gnl|extdb|FAM24227-i1-1.1_001721 883112.HMPREF9707_00339 2.59e-126 375.0 COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli,27DEM@186827|Aerococcaceae 91061|Bacilli M Glycosyl transferases group 1 - - - ko:K19424 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_001722 908337.HMPREF9257_1447 1.01e-195 559.0 COG2244@1|root,COG2244@2|Bacteria,1UY3W@1239|Firmicutes,4HEKE@91061|Bacilli,27EFW@186827|Aerococcaceae 91061|Bacilli S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C gnl|extdb|FAM24227-i1-1.1_001724 883113.HMPREF9708_00471 1.49e-91 285.0 29ZQA@1|root,30MR2@2|Bacteria,1V5VY@1239|Firmicutes,4HHY8@91061|Bacilli,27DYT@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001725 1175629.AJTG01000002_gene1309 3.23e-123 357.0 COG0463@1|root,COG0463@2|Bacteria,1TSFF@1239|Firmicutes,4HCPR@91061|Bacilli,27ECU@186827|Aerococcaceae 91061|Bacilli M Glycosyltransferase like family 2 tuaG - - ko:K16698 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 gnl|extdb|FAM24227-i1-1.1_001727 1408438.JADD01000003_gene142 5.9e-154 441.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HUAD@91061|Bacilli,27EMJ@186827|Aerococcaceae 91061|Bacilli CH Acetohydroxy acid isomeroreductase, NADPH-binding domain - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C gnl|extdb|FAM24227-i1-1.1_001728 1408438.JADD01000005_gene1222 4.09e-314 878.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,27DRB@186827|Aerococcaceae 91061|Bacilli G Carbohydrate-binding module 48 (Isoamylase N-terminal domain) pulA - - - - - - - - - - - Alpha-amylase,Big_2,CBM_48,PUD,SLH gnl|extdb|FAM24227-i1-1.1_001729 1408438.JADD01000003_gene143 5.43e-45 151.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,27E49@186827|Aerococcaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 gnl|extdb|FAM24227-i1-1.1_001730 1408438.JADD01000003_gene144 8.58e-97 291.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,27DU2@186827|Aerococcaceae 91061|Bacilli S Putative threonine/serine exporter yjjP - - - - - - - - - - - ThrE gnl|extdb|FAM24227-i1-1.1_001731 883112.HMPREF9707_00347 5.45e-75 237.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,27E2J@186827|Aerococcaceae 91061|Bacilli S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX gnl|extdb|FAM24227-i1-1.1_001732 883112.HMPREF9707_00348 3.56e-169 485.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,27DFF@186827|Aerococcaceae 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 gnl|extdb|FAM24227-i1-1.1_001733 1121871.AUAT01000002_gene1434 9.18e-204 588.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,27DEH@186827|Aerococcaceae 91061|Bacilli V the current gene model (or a revised gene model) may contain a frame shift yfiB1 - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_001734 1408438.JADD01000003_gene149 2.8e-247 699.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HCVN@91061|Bacilli,27DPS@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_10035 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_001735 592010.GCWU000182_000985 3.85e-93 277.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,27DKT@186827|Aerococcaceae 91061|Bacilli L Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Transposase_mut gnl|extdb|FAM24227-i1-1.1_001716 883113.HMPREF9708_00477 1.85e-213 599.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,27DRP@186827|Aerococcaceae 91061|Bacilli E Thermophilic metalloprotease (M29) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 gnl|extdb|FAM24227-i1-1.1_001723 1175629.AJTG01000002_gene1307 1.43e-122 365.0 COG3307@1|root,COG3307@2|Bacteria,1V5WV@1239|Firmicutes,4HF4U@91061|Bacilli,27DJV@186827|Aerococcaceae 91061|Bacilli M O-Antigen ligase tuaE - - ko:K16705 - - - - ko00000 - - - Wzy_C gnl|extdb|FAM24227-i1-1.1_001736 883112.HMPREF9707_00722 9.69e-136 404.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,27EK6@186827|Aerococcaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_001737 1336234.JAGN01000013_gene175 1.2e-130 383.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,27F7A@186828|Carnobacteriaceae 91061|Bacilli H Bacterial lipoate protein ligase C-terminus lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C gnl|extdb|FAM24227-i1-1.1_001738 1461582.BN1048_02252 3.94e-142 412.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,4GYG0@90964|Staphylococcaceae 91061|Bacilli C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase gnl|extdb|FAM24227-i1-1.1_001739 1158612.I580_00805 9.52e-129 370.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HFM5@91061|Bacilli,4B1EJ@81852|Enterococcaceae 91061|Bacilli E ABC transporter - - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001740 1158608.I583_01354 2.23e-107 319.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HBM1@91061|Bacilli,4B66D@81852|Enterococcaceae 91061|Bacilli ET NMT1/THI5 like peb1A - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_001741 1201292.DR75_190 4.28e-96 287.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HE9C@91061|Bacilli,4B66C@81852|Enterococcaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component XK27_07620 - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001743 1408438.JADD01000019_gene862 1.2e-70 223.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,27DZW@186827|Aerococcaceae 91061|Bacilli S tRNA (adenine(22)-N(1))-methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK gnl|extdb|FAM24227-i1-1.1_001744 1408438.JADD01000019_gene863 4.76e-89 272.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,27DVR@186827|Aerococcaceae 91061|Bacilli S Dinuclear metal center protein, YbgI family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 gnl|extdb|FAM24227-i1-1.1_001745 1121871.AUAT01000004_gene1128 1.32e-221 619.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,27DS2@186827|Aerococcaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 gnl|extdb|FAM24227-i1-1.1_001746 1121024.AUCD01000017_gene629 4.25e-26 101.0 COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,4HPK2@91061|Bacilli,27HKI@186828|Carnobacteriaceae 91061|Bacilli S THIoesterase - - - - - - - - - - - - 4HBT gnl|extdb|FAM24227-i1-1.1_001747 883112.HMPREF9707_00651 5.83e-296 869.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,27DIG@186827|Aerococcaceae 91061|Bacilli L PD-(D/E)XK nuclease superfamily rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C gnl|extdb|FAM24227-i1-1.1_001748 592010.GCWU000182_000203 0.0 1125.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,27DFX@186827|Aerococcaceae 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C gnl|extdb|FAM24227-i1-1.1_001749 1095726.HMPREF1116_0678 1.58e-143 424.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli 91061|Bacilli L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_001750 1408438.JADD01000009_gene1833 3.92e-204 579.0 COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,4HAPK@91061|Bacilli,27DHW@186827|Aerococcaceae 91061|Bacilli S Putative glycosyl hydrolase domain - - - - - - - - - - - - DUF4015 gnl|extdb|FAM24227-i1-1.1_001751 1408438.JADD01000009_gene1832 5.8e-68 214.0 2EHCC@1|root,33B47@2|Bacteria,1VM35@1239|Firmicutes,4HR77@91061|Bacilli,27E92@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - YkyA gnl|extdb|FAM24227-i1-1.1_001752 1121871.AUAT01000004_gene1123 2.23e-48 160.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,27E1Y@186827|Aerococcaceae 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 gnl|extdb|FAM24227-i1-1.1_001753 592010.GCWU000182_001408 1.22e-115 343.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,27DQ5@186827|Aerococcaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 gnl|extdb|FAM24227-i1-1.1_001754 1408438.JADD01000009_gene1829 7.95e-116 337.0 COG1451@1|root,COG1451@2|Bacteria,1VCK6@1239|Firmicutes,4HGVM@91061|Bacilli,27DVD@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF2786) - - - - - - - - - - - - DUF2786 gnl|extdb|FAM24227-i1-1.1_001755 1121024.AUCD01000009_gene2038 5.06e-193 554.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,27FHV@186828|Carnobacteriaceae 91061|Bacilli G Pyruvate kinase, barrel domain - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK gnl|extdb|FAM24227-i1-1.1_001742 1201292.DR75_189 2.46e-93 279.0 COG0765@1|root,COG0765@2|Bacteria,1V14N@1239|Firmicutes,4HJ9W@91061|Bacilli,4B1DK@81852|Enterococcaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component - - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001756 1266845.Q783_09980 2.24e-29 111.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_001757 1122152.AUEI01000008_gene452 6.93e-06 50.8 COG0515@1|root,COG0515@2|Bacteria,1V7E2@1239|Firmicutes,4HJ1U@91061|Bacilli,3F5II@33958|Lactobacillaceae 91061|Bacilli KLT Protein kinase domain - - - - - - - - - - - - LANC_like,Pkinase gnl|extdb|FAM24227-i1-1.1_001759 908337.HMPREF9257_1115 0.0 899.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,27DCF@186827|Aerococcaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind gnl|extdb|FAM24227-i1-1.1_001760 883112.HMPREF9707_00788 1.19e-191 539.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,27DH2@186827|Aerococcaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d gnl|extdb|FAM24227-i1-1.1_001762 883112.HMPREF9707_00790 8.01e-79 245.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,27DX0@186827|Aerococcaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind gnl|extdb|FAM24227-i1-1.1_001763 883112.HMPREF9707_00791 1.41e-237 665.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,27DKR@186827|Aerococcaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 gnl|extdb|FAM24227-i1-1.1_001764 1121871.AUAT01000016_gene263 1.78e-107 317.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,27DXY@186827|Aerococcaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 gnl|extdb|FAM24227-i1-1.1_001765 1408438.JADD01000026_gene884 2.37e-227 672.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,27DM2@186827|Aerococcaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C gnl|extdb|FAM24227-i1-1.1_001766 1408438.JADD01000026_gene885 0.0 1342.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,27DJI@186827|Aerococcaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 gnl|extdb|FAM24227-i1-1.1_001767 1408438.JADD01000026_gene886 2.94e-136 414.0 COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,27DW9@186827|Aerococcaceae 91061|Bacilli MNU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - ko:K02395,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM gnl|extdb|FAM24227-i1-1.1_001768 883112.HMPREF9707_00796 3.21e-61 195.0 COG0275@1|root,COG0275@2|Bacteria,1UHPG@1239|Firmicutes,4IS5B@91061|Bacilli 91061|Bacilli M rRNA Methylase ytqB - - - - - - - - - - - rRNA_methylase gnl|extdb|FAM24227-i1-1.1_001769 663278.Ethha_0539 2.92e-44 167.0 COG4097@1|root,COG4097@2|Bacteria 2|Bacteria P nitric oxide dioxygenase activity - - - - - - - - - - - - FAD_binding_6,FAD_binding_8,Ferric_reduct,NAD_binding_1,NAD_binding_6 gnl|extdb|FAM24227-i1-1.1_001770 439292.Bsel_0269 1.22e-43 153.0 COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,4HS9W@91061|Bacilli 91061|Bacilli S FMN-binding domain protein - - - - - - - - - - - - FMN_bind gnl|extdb|FAM24227-i1-1.1_001771 883112.HMPREF9707_00799 2.54e-199 561.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,27DG0@186827|Aerococcaceae 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N gnl|extdb|FAM24227-i1-1.1_001772 908337.HMPREF9257_1130 3.07e-63 206.0 COG1575@1|root,COG1575@2|Bacteria,1VBD7@1239|Firmicutes,4HN4T@91061|Bacilli,27E47@186827|Aerococcaceae 91061|Bacilli H Belongs to the MenA family. Type 1 subfamily - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001773 220668.lp_1708 8.64e-06 49.3 COG3237@1|root,COG3237@2|Bacteria,1VZVB@1239|Firmicutes,4HYP0@91061|Bacilli,3F7E6@33958|Lactobacillaceae 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD gnl|extdb|FAM24227-i1-1.1_001761 1408438.JADD01000026_gene880 1.35e-65 204.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli,27F6R@186827|Aerococcaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD gnl|extdb|FAM24227-i1-1.1_001796 592010.GCWU000182_000262 2.37e-81 253.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,27DKT@186827|Aerococcaceae 91061|Bacilli L Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Transposase_mut gnl|extdb|FAM24227-i1-1.1_001797 1408438.JADD01000012_gene1660 1.12e-45 158.0 COG3619@1|root,COG3619@2|Bacteria,1TXR1@1239|Firmicutes,4I63F@91061|Bacilli,27F0V@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 gnl|extdb|FAM24227-i1-1.1_001799 1260356.D920_01777 1.01e-45 151.0 COG5646@1|root,COG5646@2|Bacteria,1V6QT@1239|Firmicutes,4HIUI@91061|Bacilli,4B3ET@81852|Enterococcaceae 91061|Bacilli S Domain of unknown function (DU1801) frataxin - - ko:K05937 - - - - ko00000 - - - DUF1801 gnl|extdb|FAM24227-i1-1.1_001800 1175629.AJTG01000028_gene229 2.02e-224 631.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,27EP1@186827|Aerococcaceae 91061|Bacilli G Phosphotransferase system, EIIC celD - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001801 945021.TEH_10960 7.57e-26 103.0 2E5MG@1|root,32WCE@2|Bacteria,1UHKX@1239|Firmicutes,4IS3T@91061|Bacilli,4B5X7@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001802 1175629.AJTG01000028_gene231 4.84e-44 145.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HNWK@91061|Bacilli,27E6I@186827|Aerococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit licA_1 - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA gnl|extdb|FAM24227-i1-1.1_001803 1175629.AJTG01000028_gene232 2.26e-46 152.0 COG1440@1|root,COG1440@2|Bacteria,1VDIJ@1239|Firmicutes,4HM19@91061|Bacilli,27F1M@186827|Aerococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit celB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB gnl|extdb|FAM24227-i1-1.1_001804 1121024.AUCD01000056_gene1067 2.81e-265 736.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,27G3C@186828|Carnobacteriaceae 91061|Bacilli G Glycosyl hydrolase family 1 bglC - 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 gnl|extdb|FAM24227-i1-1.1_001805 315750.BPUM_3663 3.05e-81 249.0 COG2188@1|root,COG2188@2|Bacteria,1V2M8@1239|Firmicutes,4HGRM@91061|Bacilli,1ZDVR@1386|Bacillus 91061|Bacilli K Transcriptional regulator yydK - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA gnl|extdb|FAM24227-i1-1.1_001806 1123359.AUIQ01000018_gene249 7.47e-302 828.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,4AZGA@81852|Enterococcaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 gnl|extdb|FAM24227-i1-1.1_001807 1449342.JQMR01000001_gene2004 1.09e-248 695.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,27FP3@186828|Carnobacteriaceae 91061|Bacilli T 5TM C-terminal transporter carbon starvation CstA cstA - - - - - - - - - - - CstA,CstA_5TM gnl|extdb|FAM24227-i1-1.1_001808 1175629.AJTG01000006_gene661 9.1e-168 475.0 COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,4H9QD@91061|Bacilli,27EDJ@186827|Aerococcaceae 91061|Bacilli E Amino acid kinase family arcC - 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - - AA_kinase gnl|extdb|FAM24227-i1-1.1_001809 1408226.T233_00039 6.82e-71 224.0 COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HDIC@91061|Bacilli,4B2CU@81852|Enterococcaceae 91061|Bacilli K LytTr DNA-binding domain lytT GO:0000156,GO:0000160,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg gnl|extdb|FAM24227-i1-1.1_001811 883113.HMPREF9708_00779 1.05e-51 170.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,27EPB@186827|Aerococcaceae 91061|Bacilli I Thioesterase superfamily ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 - - - - ko00000,ko01000 - - - 4HBT gnl|extdb|FAM24227-i1-1.1_001813 1139996.OMQ_02622 9.78e-46 157.0 COG1266@1|root,COG1266@2|Bacteria,1VKZ6@1239|Firmicutes,4HQSN@91061|Bacilli,4B4AC@81852|Enterococcaceae 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi gnl|extdb|FAM24227-i1-1.1_001815 1158607.UAU_02628 3.74e-18 78.6 COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,4HR7A@91061|Bacilli,4B3VZ@81852|Enterococcaceae 91061|Bacilli L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB gnl|extdb|FAM24227-i1-1.1_001816 650150.ERH_0741 6.19e-142 412.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,3VPJK@526524|Erysipelotrichia 526524|Erysipelotrichia S Phosphotransferase system, EIIC - - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 gnl|extdb|FAM24227-i1-1.1_001817 650150.ERH_0742 3.9e-146 422.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,3VUMF@526524|Erysipelotrichia 526524|Erysipelotrichia C D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C gnl|extdb|FAM24227-i1-1.1_001818 655812.HMPREF0061_1884 1.93e-82 254.0 COG2963@1|root,COG2963@2|Bacteria,1V2T5@1239|Firmicutes,4HFZ1@91061|Bacilli,27EJ8@186827|Aerococcaceae 91061|Bacilli L Homeodomain-like domain - - - - - - - - - - - - HTH_28,HTH_Tnp_1 gnl|extdb|FAM24227-i1-1.1_001819 908337.HMPREF9257_0861 1.27e-56 181.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,27F4J@186827|Aerococcaceae 91061|Bacilli L HTH-like domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 gnl|extdb|FAM24227-i1-1.1_001820 1121024.AUCD01000132_gene1626 1.66e-40 139.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,27GPD@186828|Carnobacteriaceae 91061|Bacilli L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 gnl|extdb|FAM24227-i1-1.1_001821 908337.HMPREF9257_1415 6.75e-148 432.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HBY9@91061|Bacilli,27EIW@186827|Aerococcaceae 91061|Bacilli V MacB-like periplasmic core domain yknZ - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD gnl|extdb|FAM24227-i1-1.1_001823 883113.HMPREF9708_01185 3.97e-106 329.0 COG0845@1|root,COG0845@2|Bacteria,1VBR9@1239|Firmicutes,4HG5X@91061|Bacilli,27ECH@186827|Aerococcaceae 91061|Bacilli M Biotin-lipoyl like - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 gnl|extdb|FAM24227-i1-1.1_001824 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_001810 176279.SERP2024 8.94e-189 550.0 COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,4GX5C@90964|Staphylococcaceae 91061|Bacilli T Member of the two-component regulatory system LytR LytS that probably regulates genes involved in cell wall metabolism lytS - 2.7.13.3 ko:K07704 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase,SpoVT_C gnl|extdb|FAM24227-i1-1.1_001822 908337.HMPREF9257_1416 7.74e-115 336.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,27EJF@186827|Aerococcaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001825 592010.GCWU000182_000452 8.06e-220 618.0 COG0770@1|root,COG0770@2|Bacteria,1TRG9@1239|Firmicutes,4HAMY@91061|Bacilli,27DE1@186827|Aerococcaceae 91061|Bacilli M Mur ligase middle domain protein murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M gnl|extdb|FAM24227-i1-1.1_001826 1121871.AUAT01000014_gene381 8.63e-123 353.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli,27DUZ@186827|Aerococcaceae 91061|Bacilli S CobB/CobQ-like glutamine amidotransferase domain cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 gnl|extdb|FAM24227-i1-1.1_001827 638301.HMPREF0444_0999 2.12e-245 694.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,27FBU@186828|Carnobacteriaceae 91061|Bacilli E Oligopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N gnl|extdb|FAM24227-i1-1.1_001828 908337.HMPREF9257_1375 2.9e-84 256.0 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,27ENJ@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 gnl|extdb|FAM24227-i1-1.1_001829 592010.GCWU000182_000419 1.94e-89 288.0 28M9V@1|root,33TRW@2|Bacteria,1VUC1@1239|Firmicutes,4HVUY@91061|Bacilli,27EN5@186827|Aerococcaceae 91061|Bacilli S Domain of unknown function (DUF5068) - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001830 883113.HMPREF9708_01226 1.38e-127 380.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,27DR0@186827|Aerococcaceae 91061|Bacilli S AI-2E family transporter XK27_05220 - - - - - - - - - - - AI-2E_transport gnl|extdb|FAM24227-i1-1.1_001831 1121871.AUAT01000023_gene1060 1.16e-118 353.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,27DVG@186827|Aerococcaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase gnl|extdb|FAM24227-i1-1.1_001833 908337.HMPREF9257_1661 7.58e-229 639.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,27DEV@186827|Aerococcaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b gnl|extdb|FAM24227-i1-1.1_001834 1121871.AUAT01000011_gene557 1.31e-102 299.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,27DSW@186827|Aerococcaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase gnl|extdb|FAM24227-i1-1.1_001835 883112.HMPREF9707_00370 4.13e-79 242.0 COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,27E81@186827|Aerococcaceae 91061|Bacilli J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C gnl|extdb|FAM24227-i1-1.1_001836 1121871.AUAT01000011_gene560 4e-52 168.0 COG5341@1|root,COG5341@2|Bacteria,1VCR8@1239|Firmicutes,4HKP0@91061|Bacilli,27E89@186827|Aerococcaceae 91061|Bacilli S NusG domain II - - - - - - - - - - - - NusG_II gnl|extdb|FAM24227-i1-1.1_001837 1385510.N781_18225 1.7e-51 167.0 2CHCP@1|root,32S5R@2|Bacteria,1V3HI@1239|Firmicutes,4HGYA@91061|Bacilli,2YAIU@289201|Pontibacillus 91061|Bacilli S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 gnl|extdb|FAM24227-i1-1.1_001838 1121871.AUAT01000037_gene1333 2.19e-114 340.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,27EKS@186827|Aerococcaceae 91061|Bacilli H UbiA prenyltransferase family ubiA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA gnl|extdb|FAM24227-i1-1.1_001840 1123304.AQYA01000028_gene1732 1.75e-30 122.0 COG4939@1|root,COG4939@2|Bacteria,1TSWI@1239|Firmicutes,4HEJH@91061|Bacilli 91061|Bacilli M FMN_bind - - - ko:K20379 ko02024,map02024 - - - ko00000,ko00001 - - - FMN_bind gnl|extdb|FAM24227-i1-1.1_001841 592010.GCWU000182_000952 6.21e-90 278.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,27EHB@186827|Aerococcaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt gnl|extdb|FAM24227-i1-1.1_001842 908337.HMPREF9257_1673 0.0 903.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,27EKI@186827|Aerococcaceae 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DoxX,Pyr_redox_2 gnl|extdb|FAM24227-i1-1.1_001844 883112.HMPREF9707_00365 1.14e-122 363.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,27E0A@186827|Aerococcaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 gnl|extdb|FAM24227-i1-1.1_001845 883112.HMPREF9707_00366 2.29e-36 127.0 COG4980@1|root,COG4980@2|Bacteria,1VF0X@1239|Firmicutes,4HP1X@91061|Bacilli,27F64@186827|Aerococcaceae 91061|Bacilli S YtxH-like protein - - - - - - - - - - - - YtxH gnl|extdb|FAM24227-i1-1.1_001846 1122146.AUHP01000009_gene831 1.22e-64 200.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,3F6K5@33958|Lactobacillaceae 91061|Bacilli FG histidine triad hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT gnl|extdb|FAM24227-i1-1.1_001847 883113.HMPREF9708_00201 1.89e-41 149.0 2C30J@1|root,332HD@2|Bacteria,1VGUU@1239|Firmicutes,4HQAZ@91061|Bacilli,27E6K@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001848 1121871.AUAT01000037_gene1338 9.03e-75 229.0 COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,4HG1H@91061|Bacilli,27EQR@186827|Aerococcaceae 91061|Bacilli S Heptaprenyl diphosphate synthase component I hepA - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - Hpre_diP_synt_I gnl|extdb|FAM24227-i1-1.1_001832 1408438.JADD01000018_gene640 1.8e-137 395.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,27DT9@186827|Aerococcaceae 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA gnl|extdb|FAM24227-i1-1.1_001839 1121871.AUAT01000037_gene1334 1.63e-150 436.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,27EM2@186827|Aerococcaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE gnl|extdb|FAM24227-i1-1.1_001850 562981.HMPREF0428_01861 4.84e-08 54.7 2E3K1@1|root,32YIA@2|Bacteria,1VHW3@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001851 655812.HMPREF0061_0847 1.1e-128 381.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HFJ7@91061|Bacilli,27EA1@186827|Aerococcaceae 91061|Bacilli C Iron-containing alcohol dehydrogenase - - 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 - R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 - - - Fe-ADH gnl|extdb|FAM24227-i1-1.1_001852 1408438.JADD01000002_gene366 4.87e-129 371.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,27DN6@186827|Aerococcaceae 91061|Bacilli E ATPases associated with a variety of cellular activities glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001856 866775.HMPREF9243_0209 3.06e-29 113.0 2ETWI@1|root,3311F@2|Bacteria,1VHYS@1239|Firmicutes,4HQXB@91061|Bacilli,27F58@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001857 1121870.AUAA01000038_gene2829 0.000268 43.5 COG1476@1|root,COG1476@2|Bacteria,4PKS7@976|Bacteroidetes,1I6P5@117743|Flavobacteriia 976|Bacteroidetes K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 gnl|extdb|FAM24227-i1-1.1_001858 883112.HMPREF9707_00096 9.64e-140 417.0 COG4529@1|root,COG4529@2|Bacteria,1UZWK@1239|Firmicutes,4HDAF@91061|Bacilli 91061|Bacilli S FAD-NAD(P)-binding - - - - - - - - - - - - NAD_binding_9 gnl|extdb|FAM24227-i1-1.1_001860 208596.CAR_c15280 3.83e-185 526.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4HA5T@91061|Bacilli,27H5Y@186828|Carnobacteriaceae 91061|Bacilli C Metalloenzyme superfamily - - - - - - - - - - - - Metalloenzyme gnl|extdb|FAM24227-i1-1.1_001861 208596.CAR_c15290 1.25e-135 399.0 COG3457@1|root,COG3457@2|Bacteria,1TSX7@1239|Firmicutes,4HCY0@91061|Bacilli,27GZM@186828|Carnobacteriaceae 91061|Bacilli E Alanine racemase, N-terminal domain - - - - - - - - - - - - Ala_racemase_N gnl|extdb|FAM24227-i1-1.1_001862 1140002.I570_00633 3.55e-11 62.8 2BJ4V@1|root,32DDZ@2|Bacteria,1UP04@1239|Firmicutes,4IUW9@91061|Bacilli,4B427@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - PRD gnl|extdb|FAM24227-i1-1.1_001865 208596.CAR_c15330 5.75e-146 418.0 COG1735@1|root,COG1735@2|Bacteria,1TS8I@1239|Firmicutes,4HC5T@91061|Bacilli,27GKR@186828|Carnobacteriaceae 91061|Bacilli S Phosphotriesterase family php - - ko:K07048 - - - - ko00000 - - - PTE gnl|extdb|FAM24227-i1-1.1_001866 208596.CAR_c15340 2.57e-197 560.0 2CGY9@1|root,2Z8E9@2|Bacteria,1TQKB@1239|Firmicutes,4HBZ1@91061|Bacilli,27H3B@186828|Carnobacteriaceae 91061|Bacilli S Protein of unknown function - - - - - - - - - - - - YhfT gnl|extdb|FAM24227-i1-1.1_001867 1140002.I570_00638 2.67e-50 162.0 2CDRP@1|root,32N2F@2|Bacteria,1VA2X@1239|Firmicutes,4HK7H@91061|Bacilli,4B3SK@81852|Enterococcaceae 91061|Bacilli S Protein of unknown function DUF2620 - - - - - - - - - - - - DUF2620 gnl|extdb|FAM24227-i1-1.1_001868 208596.CAR_c15360 2.52e-72 234.0 COG0154@1|root,COG0154@2|Bacteria,1V1V1@1239|Firmicutes,4HI6G@91061|Bacilli,27HBU@186828|Carnobacteriaceae 91061|Bacilli J Amidase - - - - - - - - - - - - Amidase gnl|extdb|FAM24227-i1-1.1_001869 1175629.AJTG01000031_gene1414 4.48e-22 92.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,27ES1@186827|Aerococcaceae 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_001870 883113.HMPREF9708_01421 1.14e-22 95.5 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,27ES1@186827|Aerococcaceae 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_001853 655812.HMPREF0061_0578 4.31e-178 524.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,27DG8@186827|Aerococcaceae 91061|Bacilli P Bacterial periplasmic substrate-binding proteins glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 gnl|extdb|FAM24227-i1-1.1_001859 1280689.AUJC01000003_gene1368 9.65e-160 468.0 COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia,36H4V@31979|Clostridiaceae 186801|Clostridia V beta-lactamase - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase,Cu_amine_oxidN1,DUF3471 gnl|extdb|FAM24227-i1-1.1_001863 208596.CAR_c15310 4.6e-99 300.0 COG0715@1|root,COG0715@2|Bacteria,1V2J5@1239|Firmicutes,4HHM0@91061|Bacilli 91061|Bacilli P YhfZ C-terminal domain - - - - - - - - - - - - HTH_41,YhfZ_C gnl|extdb|FAM24227-i1-1.1_001864 1140002.I570_00635 2.01e-150 435.0 COG4100@1|root,COG4100@2|Bacteria,1TSSP@1239|Firmicutes,4ISTX@91061|Bacilli,4AZB0@81852|Enterococcaceae 91061|Bacilli P Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 gnl|extdb|FAM24227-i1-1.1_001872 1122128.AUEE01000006_gene2058 3.64e-34 119.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,4GYPD@90964|Staphylococcaceae 91061|Bacilli L Transposase for ISSha1 - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_001873 1408226.T233_00742 7.65e-58 215.0 COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,4AZE2@81852|Enterococcaceae 91061|Bacilli MNU defense response to other organism acmA GO:0005575,GO:0005576 - ko:K02395,ko:K19220,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM gnl|extdb|FAM24227-i1-1.1_001874 638301.HMPREF0444_0038 2.26e-268 749.0 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,27FN8@186828|Carnobacteriaceae 91061|Bacilli C Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP gnl|extdb|FAM24227-i1-1.1_001875 1158607.UAU_03764 3.8e-35 120.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,4B3D4@81852|Enterococcaceae 91061|Bacilli K Cold shock cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD gnl|extdb|FAM24227-i1-1.1_001877 1408438.JADD01000002_gene331 1.65e-98 295.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,27ES6@186827|Aerococcaceae 91061|Bacilli C Nitroreductase family nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase gnl|extdb|FAM24227-i1-1.1_001878 211110.gbs1694 4.18e-173 490.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4H9VS@91061|Bacilli 91061|Bacilli G Dihydroxyacetone kinase dhaK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 gnl|extdb|FAM24227-i1-1.1_001879 391295.SSU05_1958 1.65e-74 229.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli,1WSN0@1307|Streptococcus suis 91061|Bacilli S Dak2 dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 gnl|extdb|FAM24227-i1-1.1_001880 218495.SUB0545 1.56e-49 160.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes 1239|Firmicutes S dihydroxyacetone kinase, phosphotransfer subunit dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 - - - EIIA-man gnl|extdb|FAM24227-i1-1.1_001881 1000570.HMPREF9966_1354 5.16e-100 297.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,42E9F@671232|Streptococcus anginosus group 91061|Bacilli P Major intrinsic protein glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP gnl|extdb|FAM24227-i1-1.1_001882 1154860.SAG0136_10685 7.75e-273 757.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N gnl|extdb|FAM24227-i1-1.1_001883 655812.HMPREF0061_1080 6.5e-235 669.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,27EIC@186827|Aerococcaceae 91061|Bacilli C C-terminal domain of alpha-glycerophosphate oxidase glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C gnl|extdb|FAM24227-i1-1.1_001884 1123314.AUIO01000003_gene1153 1.77e-189 540.0 COG0366@1|root,COG0366@2|Bacteria,1U7JS@1239|Firmicutes,4HF0J@91061|Bacilli 91061|Bacilli G Alpha amylase malS - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase gnl|extdb|FAM24227-i1-1.1_001885 1121871.AUAT01000007_gene1617 2.91e-211 593.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,27DS9@186827|Aerococcaceae 91061|Bacilli G maltodextrin-binding protein MdxE mdxE - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - iYO844.BSU34610 SBP_bac_8 gnl|extdb|FAM24227-i1-1.1_001886 908337.HMPREF9257_0470 1.31e-229 642.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,27DD2@186827|Aerococcaceae 91061|Bacilli P ABC transporter, permease protein malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001887 1121871.AUAT01000007_gene1620 6.34e-163 460.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli,27DR4@186827|Aerococcaceae 91061|Bacilli P ABC transporter, permease protein malD GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043211,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_001888 592010.GCWU000182_001212 2.24e-45 161.0 COG5521@1|root,COG5521@2|Bacteria,1V7S4@1239|Firmicutes,4HGZG@91061|Bacilli,27E8Q@186827|Aerococcaceae 91061|Bacilli S maltodextrose utilization protein MalA malA - - - - - - - - - - - DUF1189 gnl|extdb|FAM24227-i1-1.1_001889 1139219.I569_02477 3.5e-196 551.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,4AZ72@81852|Enterococcaceae 91061|Bacilli E TOBE domain msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 gnl|extdb|FAM24227-i1-1.1_001890 592010.GCWU000182_001616 3.06e-199 560.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,27DNH@186827|Aerococcaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 gnl|extdb|FAM24227-i1-1.1_001891 883114.HMPREF9709_00199 4.16e-135 392.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,22JB8@1570339|Peptoniphilaceae 186801|Clostridia S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red gnl|extdb|FAM24227-i1-1.1_001892 883113.HMPREF9708_01224 5.09e-50 165.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,27EQG@186827|Aerococcaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 gnl|extdb|FAM24227-i1-1.1_001893 1122128.AUEE01000006_gene2058 6.89e-34 118.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,4GYPD@90964|Staphylococcaceae 91061|Bacilli L Transposase for ISSha1 - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_001895 908337.HMPREF9257_0138 5.71e-176 504.0 COG0668@1|root,COG0668@2|Bacteria,1TQXJ@1239|Firmicutes,4HCK2@91061|Bacilli,27DBU@186827|Aerococcaceae 91061|Bacilli M Conserved TM helix ygxB - - - - - - - - - - - TM_helix gnl|extdb|FAM24227-i1-1.1_001896 1121024.AUCD01000056_gene1065 8.31e-146 418.0 COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,27H36@186828|Carnobacteriaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase yhxD - - - - - - - - - - - adh_short_C2 gnl|extdb|FAM24227-i1-1.1_001897 1229520.ADIAL_1214 8.49e-191 540.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,27FXT@186828|Carnobacteriaceae 91061|Bacilli M UDP binding domain ugd GO:0003674,GO:0003824,GO:0003979,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N gnl|extdb|FAM24227-i1-1.1_001898 866775.HMPREF9243_0729 4.08e-277 774.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,27DE3@186827|Aerococcaceae 91061|Bacilli G phosphotransferase system, EIIB ptsG - 2.7.1.199,2.7.1.208 ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.3 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001899 866775.HMPREF9243_0728 8.4e-128 367.0 COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,4HBPF@91061|Bacilli,27DXI@186827|Aerococcaceae 91061|Bacilli G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) nanE - 5.1.3.9 ko:K01788 ko00520,map00520 - R02087 RC00290 ko00000,ko00001,ko01000 - - - NanE gnl|extdb|FAM24227-i1-1.1_001900 883103.HMPREF9703_00647 1.48e-84 261.0 COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,4HFAM@91061|Bacilli,27HV9@186828|Carnobacteriaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS gnl|extdb|FAM24227-i1-1.1_001901 743719.PaelaDRAFT_4154 1e-72 229.0 COG1266@1|root,COG1266@2|Bacteria,1TYWG@1239|Firmicutes,4I827@91061|Bacilli,26YN3@186822|Paenibacillaceae 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi gnl|extdb|FAM24227-i1-1.1_001902 565655.ECBG_01553 0.0 1188.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,4AZHB@81852|Enterococcaceae 91061|Bacilli G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N gnl|extdb|FAM24227-i1-1.1_001903 883113.HMPREF9708_00261 1.08e-66 211.0 COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,27EN0@186827|Aerococcaceae 91061|Bacilli O Cytochrome C biogenesis protein transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD gnl|extdb|FAM24227-i1-1.1_001904 592010.GCWU000182_001535 1.38e-35 132.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,27E39@186827|Aerococcaceae 91061|Bacilli CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin gnl|extdb|FAM24227-i1-1.1_001905 1449337.JQLL01000001_gene1858 1.22e-62 218.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,27FMT@186828|Carnobacteriaceae 91061|Bacilli G FGGY family of carbohydrate kinases, N-terminal domain gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N gnl|extdb|FAM24227-i1-1.1_001906 360911.EAT1b_1206 1.77e-15 76.3 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3WG6A@539002|Bacillales incertae sedis 91061|Bacilli G 6-phosphogluconate dehydrogenase - - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 gnl|extdb|FAM24227-i1-1.1_001909 1123309.AQYB01000028_gene745 2.33e-06 50.4 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli 91061|Bacilli G transcriptional antiterminator - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB gnl|extdb|FAM24227-i1-1.1_001910 866775.HMPREF9243_0755 1.34e-38 135.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - ThrE_2 gnl|extdb|FAM24227-i1-1.1_001911 883112.HMPREF9707_00256 1.28e-74 234.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,27DU2@186827|Aerococcaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE gnl|extdb|FAM24227-i1-1.1_001912 1121024.AUCD01000007_gene1983 4.05e-279 783.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,27FJ8@186828|Carnobacteriaceae 91061|Bacilli P E1-E2 ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase gnl|extdb|FAM24227-i1-1.1_001914 1499685.CCFJ01000041_gene819 0.0 935.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZCU8@1386|Bacillus 91061|Bacilli P E1-E2 ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase gnl|extdb|FAM24227-i1-1.1_001915 1121024.AUCD01000093_gene361 2.94e-37 127.0 COG2846@1|root,COG2846@2|Bacteria,1V6WD@1239|Firmicutes,4HJ48@91061|Bacilli,27GJ9@186828|Carnobacteriaceae 91061|Bacilli D Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - ko:K07322 - - - - ko00000 - - - - gnl|extdb|FAM24227-i1-1.1_001916 1499685.CCFJ01000039_gene1201 4.54e-32 113.0 COG2608@1|root,COG2608@2|Bacteria,1VG8U@1239|Firmicutes,4HNAN@91061|Bacilli,1ZR31@1386|Bacillus 91061|Bacilli P Heavy-metal-associated domain - - - - - - - - - - - - HMA gnl|extdb|FAM24227-i1-1.1_001894 1157490.EL26_00490 3.99e-08 51.6 COG1942@1|root,COG1942@2|Bacteria,1U4P7@1239|Firmicutes,4I3V1@91061|Bacilli,27AJV@186823|Alicyclobacillaceae 91061|Bacilli S Tautomerase enzyme - - - - - - - - - - - - Tautomerase gnl|extdb|FAM24227-i1-1.1_001913 1449338.JQLU01000001_gene941 1.7e-89 269.0 COG0664@1|root,COG0664@2|Bacteria,1U9VC@1239|Firmicutes,4HBWK@91061|Bacilli,27GZ6@186828|Carnobacteriaceae 91061|Bacilli T helix_turn_helix, cAMP Regulatory protein - - - ko:K21562 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding gnl|extdb|FAM24227-i1-1.1_001917 883112.HMPREF9707_00464 6.22e-301 833.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,27DKG@186827|Aerococcaceae 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL gnl|extdb|FAM24227-i1-1.1_001918 883113.HMPREF9708_00068 1.81e-52 174.0 COG3859@1|root,COG3859@2|Bacteria,1VE0U@1239|Firmicutes,4HKNA@91061|Bacilli,27E1V@186827|Aerococcaceae 91061|Bacilli S Thiamine transporter protein (Thia_YuaJ) - - - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ gnl|extdb|FAM24227-i1-1.1_001919 1121105.ATXL01000011_gene1945 0.00022 44.7 2C5BC@1|root,2ZPT0@2|Bacteria,1W4YZ@1239|Firmicutes,4I1Z3@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001920 208596.CAR_c15540 2.94e-59 200.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,27FD2@186828|Carnobacteriaceae 91061|Bacilli K Cell envelope-related transcriptional attenuator domain brpA - - - - - - - - - - - LytR_cpsA_psr gnl|extdb|FAM24227-i1-1.1_001921 883112.HMPREF9707_00467 8.05e-121 348.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,27DTQ@186827|Aerococcaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin gnl|extdb|FAM24227-i1-1.1_001922 592010.GCWU000182_000123 2.08e-25 95.5 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,27E7X@186827|Aerococcaceae 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 gnl|extdb|FAM24227-i1-1.1_001923 1121871.AUAT01000001_gene806 0.0 943.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,27DRU@186827|Aerococcaceae 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII gnl|extdb|FAM24227-i1-1.1_001924 883112.HMPREF9707_00470 2.27e-137 399.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,27DM6@186827|Aerococcaceae 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N gnl|extdb|FAM24227-i1-1.1_001925 883112.HMPREF9707_00471 3.11e-174 503.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,27DCH@186827|Aerococcaceae 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB gnl|extdb|FAM24227-i1-1.1_001926 883112.HMPREF9707_00472 2.64e-101 302.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,27DU7@186827|Aerococcaceae 91061|Bacilli T Sigma factor PP2C-like phosphatases stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 gnl|extdb|FAM24227-i1-1.1_001927 883112.HMPREF9707_00473 7.72e-298 833.0 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27DCX@186827|Aerococcaceae 91061|Bacilli KLT Protein kinase domain prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase gnl|extdb|FAM24227-i1-1.1_001928 883113.HMPREF9708_00059 8.63e-126 368.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,27DD4@186827|Aerococcaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N gnl|extdb|FAM24227-i1-1.1_001929 883112.HMPREF9707_00475 4.99e-100 295.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,27DXN@186827|Aerococcaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim gnl|extdb|FAM24227-i1-1.1_001930 1408438.JADD01000023_gene17 3.13e-68 216.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,27E3K@186827|Aerococcaceae 91061|Bacilli H Thiamin pyrophosphokinase, vitamin B1 binding domain thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic gnl|extdb|FAM24227-i1-1.1_001931 908337.HMPREF9257_1256 8.63e-82 257.0 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,27EMQ@186827|Aerococcaceae 91061|Bacilli C D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C gnl|extdb|FAM24227-i1-1.1_001932 1408438.JADD01000023_gene15 3.37e-34 117.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 gnl|extdb|FAM24227-i1-1.1_001933 1408438.JADD01000023_gene14 2.27e-60 187.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,27E3C@186827|Aerococcaceae 91061|Bacilli S Asp23 family, cell envelope-related function yloU - - - - - - - - - - - Asp23 gnl|extdb|FAM24227-i1-1.1_001934 592010.GCWU000182_000111 8.4e-252 708.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,27DSE@186827|Aerococcaceae 91061|Bacilli S DAK2 domain fusion protein YloV yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 gnl|extdb|FAM24227-i1-1.1_001935 592010.GCWU000182_000110 2.1e-297 833.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,27DFR@186827|Aerococcaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge gnl|extdb|FAM24227-i1-1.1_001936 592010.GCWU000182_000109 4.46e-147 424.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,27DSM@186827|Aerococcaceae 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis gnl|extdb|FAM24227-i1-1.1_001937 698758.AXY_17360 0.0 1171.0 COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal gnl|extdb|FAM24227-i1-1.1_001940 1158607.UAU_04004 0.000789 45.4 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HK15@91061|Bacilli,4B0P3@81852|Enterococcaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA gnl|extdb|FAM24227-i1-1.1_001942 1449335.JQLG01000004_gene556 5.65e-49 174.0 2EFWI@1|root,339NT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001943 655812.HMPREF0061_1527 2.07e-182 521.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,27ECN@186827|Aerococcaceae 91061|Bacilli L Protein of unknown function (DUF1722) uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - DUF1722,UvdE gnl|extdb|FAM24227-i1-1.1_001944 1266845.Q783_08830 5.58e-108 317.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,27G0W@186828|Carnobacteriaceae 91061|Bacilli V ATPases associated with a variety of cellular activities lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_001945 1266845.Q783_08835 4.17e-157 452.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,27FMB@186828|Carnobacteriaceae 91061|Bacilli V FtsX-like permease family yxeA - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD gnl|extdb|FAM24227-i1-1.1_001946 655812.HMPREF0061_1572 2.62e-59 190.0 COG1309@1|root,COG1309@2|Bacteria,1VCQD@1239|Firmicutes,4HMVC@91061|Bacilli 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N gnl|extdb|FAM24227-i1-1.1_001949 1122129.AUEF01000001_gene925 6.92e-21 98.6 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,4GZ3K@90964|Staphylococcaceae 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD gnl|extdb|FAM24227-i1-1.1_001950 1395587.P364_0127175 4.6e-19 81.6 COG0640@1|root,COG0640@2|Bacteria,1VF14@1239|Firmicutes,4HP8Z@91061|Bacilli,26YZT@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_20,HTH_5 gnl|extdb|FAM24227-i1-1.1_001951 1449335.JQLG01000004_gene817 5.93e-134 387.0 COG1307@1|root,COG1307@2|Bacteria,1TQQG@1239|Firmicutes,4HBFM@91061|Bacilli,27HPH@186828|Carnobacteriaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV gnl|extdb|FAM24227-i1-1.1_001952 37659.JNLN01000001_gene2363 2.83e-16 90.1 2EBI4@1|root,335IJ@2|Bacteria,1VEYS@1239|Firmicutes,24NZF@186801|Clostridia 186801|Clostridia S TerB-C domain - - - - - - - - - - - - TerB_C gnl|extdb|FAM24227-i1-1.1_001953 37659.JNLN01000001_gene2361 1.44e-189 561.0 COG1201@1|root,COG1201@2|Bacteria,1UHYQ@1239|Firmicutes,25E79@186801|Clostridia,36F0R@31979|Clostridiaceae 186801|Clostridia L DEAD DEAH box helicase - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C gnl|extdb|FAM24227-i1-1.1_001954 938278.CAJO01000061_gene979 4e-194 552.0 COG1135@1|root,COG1135@2|Bacteria,1TQPH@1239|Firmicutes,248JX@186801|Clostridia 186801|Clostridia P P-loop Domain of unknown function (DUF2791) - - - - - - - - - - - - DUF2791 gnl|extdb|FAM24227-i1-1.1_001941 565655.ECBG_00276 2.05e-45 160.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HK15@91061|Bacilli,4B0P3@81852|Enterococcaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA gnl|extdb|FAM24227-i1-1.1_001955 1408438.JADD01000006_gene1010 4.44e-19 86.7 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,27F2Z@186827|Aerococcaceae 91061|Bacilli P NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_001956 908337.HMPREF9257_0757 6.75e-79 239.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,27DYE@186827|Aerococcaceae 91061|Bacilli C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR gnl|extdb|FAM24227-i1-1.1_001957 1449343.JQLQ01000002_gene2435 3.71e-83 246.0 COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,4HJ7X@91061|Bacilli,27G7D@186828|Carnobacteriaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gloA - 4.4.1.5 ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 M00491 R02530 RC00004,RC00740 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.16,3.A.1.1.2 - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_001958 994573.T472_0204290 2.13e-74 233.0 COG0730@1|root,COG0730@2|Bacteria,1UCVY@1239|Firmicutes,24BST@186801|Clostridia,36RJG@31979|Clostridiaceae 186801|Clostridia S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE gnl|extdb|FAM24227-i1-1.1_001959 1121105.ATXL01000003_gene842 3.51e-143 412.0 COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,4HC5J@91061|Bacilli,4AZN1@81852|Enterococcaceae 91061|Bacilli K Bacterial regulatory helix-turn-helix protein, lysR family cpsY - - - - - - - - - - - HTH_1,LysR_substrate gnl|extdb|FAM24227-i1-1.1_001960 1121105.ATXL01000003_gene843 5.22e-220 614.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,4B0B6@81852|Enterococcaceae 91061|Bacilli E Methionine synthase XK27_05470 - - - - - - - - - - - Meth_synt_2 gnl|extdb|FAM24227-i1-1.1_001963 1449343.JQLQ01000002_gene2434 8.03e-165 463.0 COG0625@1|root,COG0625@2|Bacteria,1TPZ7@1239|Firmicutes,4HD0K@91061|Bacilli,27FUU@186828|Carnobacteriaceae 91061|Bacilli O Glutathione S-transferase, N-terminal domain gst - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N,GST_N_2 gnl|extdb|FAM24227-i1-1.1_001964 945021.TEH_13710 1.78e-51 173.0 COG2153@1|root,COG3663@1|root,COG2153@2|Bacteria,COG3663@2|Bacteria,1V6GI@1239|Firmicutes,4HH33@91061|Bacilli,4B5ZE@81852|Enterococcaceae 91061|Bacilli L Uracil DNA glycosylase superfamily - - 3.2.2.28 ko:K03649 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Acetyltransf_10,UDG gnl|extdb|FAM24227-i1-1.1_001965 1121864.OMO_00363 2.23e-33 126.0 COG1073@1|root,COG1073@2|Bacteria,1V5W8@1239|Firmicutes 1239|Firmicutes S alpha beta - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001966 592010.GCWU000182_001580 1.48e-61 204.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,27DX6@186827|Aerococcaceae 91061|Bacilli S EDD domain protein, DegV family XK27_08360 - - - - - - - - - - - DegV gnl|extdb|FAM24227-i1-1.1_001968 565653.EGBG_00359 3.75e-126 371.0 COG1609@1|root,COG1609@2|Bacteria,1TSIJ@1239|Firmicutes,4HC90@91061|Bacilli,4B2F7@81852|Enterococcaceae 91061|Bacilli K helix_turn _helix lactose operon repressor scrR - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4 gnl|extdb|FAM24227-i1-1.1_001969 1336234.JAGN01000034_gene950 5.97e-233 652.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,27FIH@186828|Carnobacteriaceae 91061|Bacilli G phosphotransferase system, EIIB sacP - 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC gnl|extdb|FAM24227-i1-1.1_001970 883103.HMPREF9703_00865 1.6e-223 630.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,27FJR@186828|Carnobacteriaceae 91061|Bacilli G Glycosyl hydrolases family 32 sacA - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N gnl|extdb|FAM24227-i1-1.1_001971 626369.HMPREF0446_01412 3.84e-98 308.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,27FKK@186828|Carnobacteriaceae 91061|Bacilli S Transporter associated domain hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 gnl|extdb|FAM24227-i1-1.1_001972 1121024.AUCD01000007_gene1976 3.42e-69 216.0 COG2897@1|root,COG2897@2|Bacteria 2|Bacteria P thiosulfate sulfurtransferase activity - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese gnl|extdb|FAM24227-i1-1.1_001973 1449342.JQMR01000001_gene243 8.16e-33 117.0 COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,4HIWV@91061|Bacilli,27GX5@186828|Carnobacteriaceae 91061|Bacilli C Domain of Unknown Function (DUF326) - - - - - - - - - - - - DUF326 gnl|extdb|FAM24227-i1-1.1_001974 1121024.AUCD01000028_gene1316 7.57e-158 459.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,27G24@186828|Carnobacteriaceae 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth gnl|extdb|FAM24227-i1-1.1_001962 1408438.JADD01000010_gene1930 5.67e-229 648.0 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,27EGX@186827|Aerococcaceae 91061|Bacilli P Sodium/hydrogen exchanger family nhaP - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C gnl|extdb|FAM24227-i1-1.1_001967 1449343.JQLQ01000002_gene2430 2.86e-215 602.0 COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,4HCSV@91061|Bacilli,27F74@186828|Carnobacteriaceae 91061|Bacilli I NAD(P)H binding domain of trans-2-enoyl-CoA reductase fabV - 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase gnl|extdb|FAM24227-i1-1.1_001975 1408438.JADD01000013_gene1750 3.58e-264 726.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,27DBS@186827|Aerococcaceae 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - iSB619.SA_RS02960 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 gnl|extdb|FAM24227-i1-1.1_001976 1408438.JADD01000013_gene1749 0.0 1204.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,27DIY@186827|Aerococcaceae 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 gnl|extdb|FAM24227-i1-1.1_001977 883112.HMPREF9707_00179 5.44e-104 301.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,27DVZ@186827|Aerococcaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 gnl|extdb|FAM24227-i1-1.1_001978 883110.HMPREF9260_01512 3.57e-86 254.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,27DTU@186827|Aerococcaceae 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 gnl|extdb|FAM24227-i1-1.1_001979 1121871.AUAT01000010_gene688 2.34e-33 117.0 COG2388@1|root,COG2388@2|Bacteria,1U608@1239|Firmicutes,4I626@91061|Bacilli,27E5M@186827|Aerococcaceae 91061|Bacilli S GCN5-related N-acetyl-transferase - - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG gnl|extdb|FAM24227-i1-1.1_001980 1408438.JADD01000013_gene1745 5.14e-301 828.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,27DGB@186827|Aerococcaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon gnl|extdb|FAM24227-i1-1.1_001981 592010.GCWU000182_001882 5.68e-118 348.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,27DJU@186827|Aerococcaceae 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 gnl|extdb|FAM24227-i1-1.1_001982 655812.HMPREF0061_0170 2.57e-213 607.0 COG4670@1|root,COG4670@2|Bacteria,1TP5H@1239|Firmicutes,4IS4T@91061|Bacilli,27E9U@186827|Aerococcaceae 91061|Bacilli I Belongs to the 3-oxoacid CoA-transferase family pct - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans gnl|extdb|FAM24227-i1-1.1_001983 655812.HMPREF0061_0172 1.43e-175 496.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,27EMB@186827|Aerococcaceae 91061|Bacilli C Nitronate monooxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO gnl|extdb|FAM24227-i1-1.1_001984 655812.HMPREF0061_0173 5.48e-173 488.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,27EQ9@186827|Aerococcaceae 91061|Bacilli K LysR substrate binding domain protein - - - - - - - - - - - - HTH_1,LysR_substrate gnl|extdb|FAM24227-i1-1.1_001985 655812.HMPREF0061_0174 5.06e-119 347.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,27EQK@186827|Aerococcaceae 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 gnl|extdb|FAM24227-i1-1.1_001986 655812.HMPREF0061_0175 4.83e-251 693.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,27EDV@186827|Aerococcaceae 91061|Bacilli I Beta-ketoacyl synthase, N-terminal domain fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N gnl|extdb|FAM24227-i1-1.1_001987 655812.HMPREF0061_0176 0.0 1149.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,27EHJ@186827|Aerococcaceae 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 gnl|extdb|FAM24227-i1-1.1_001988 655812.HMPREF0061_0177 2.34e-252 696.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,27EBY@186827|Aerococcaceae 91061|Bacilli C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.6 ko:K00252,ko:K18244 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N gnl|extdb|FAM24227-i1-1.1_001989 1179226.AJXO01000074_gene2675 1.14e-198 569.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,4GYMI@90964|Staphylococcaceae 91061|Bacilli IQ AMP-binding enzyme - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C gnl|extdb|FAM24227-i1-1.1_001990 1175629.AJTG01000005_gene745 2.23e-178 507.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli 91061|Bacilli G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase gnl|extdb|FAM24227-i1-1.1_001992 1122927.KB895423_gene3747 7.29e-98 293.0 COG1028@1|root,COG1028@2|Bacteria,1UJNN@1239|Firmicutes,4HFTZ@91061|Bacilli,26VGN@186822|Paenibacillaceae 91061|Bacilli IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG3 - 1.1.1.100,1.1.1.385 ko:K00059,ko:K19548 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572,M00787 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10917,R11671 RC00029,RC00117,RC00154 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 gnl|extdb|FAM24227-i1-1.1_001993 1408438.JADD01000006_gene982 3.83e-104 311.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli 91061|Bacilli P Belongs to the NlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_001994 908337.HMPREF9257_1380 5.32e-86 255.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,27E08@186827|Aerococcaceae 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS gnl|extdb|FAM24227-i1-1.1_001995 1132509.C447_07743 9.34e-10 60.8 arCOG10731@1|root,arCOG10731@2157|Archaea,2XVNQ@28890|Euryarchaeota,23UMX@183963|Halobacteria 183963|Halobacteria S Sugar-transfer associated ATP-grasp - - - - - - - - - - - - ATPgrasp_ST gnl|extdb|FAM24227-i1-1.1_001996 1408438.JADD01000042_gene682 1.42e-124 378.0 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1UZDP@1239|Firmicutes,4ITUP@91061|Bacilli,27E1D@186827|Aerococcaceae 91061|Bacilli M CW_7 repeat - - - - - - - - - - - - CHAP,CW_7,Glucosaminidase,LysM gnl|extdb|FAM24227-i1-1.1_001997 866775.HMPREF9243_0213 6.5e-18 77.4 2EK5K@1|root,33DW0@2|Bacteria,1VKGK@1239|Firmicutes,4HRYF@91061|Bacilli,27E8G@186827|Aerococcaceae 91061|Bacilli S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 gnl|extdb|FAM24227-i1-1.1_001998 1408438.JADD01000042_gene684 0.000116 44.3 2DTCD@1|root,33JPQ@2|Bacteria,1VPUB@1239|Firmicutes,4HSDK@91061|Bacilli,27E9G@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_001999 866775.HMPREF9243_0211 1.22e-22 89.4 2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,4HRAS@91061|Bacilli,27E8C@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF2922) - - - - - - - - - - - - DUF2922 gnl|extdb|FAM24227-i1-1.1_002001 883113.HMPREF9708_00623 8.1e-261 730.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,27DI3@186827|Aerococcaceae 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 oppA2 - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_002002 638301.HMPREF0444_1582 4.07e-170 489.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HEAQ@91061|Bacilli,27H80@186828|Carnobacteriaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides - - 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 gnl|extdb|FAM24227-i1-1.1_002003 1121105.ATXL01000006_gene1325 7.13e-11 64.3 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,4B0H2@81852|Enterococcaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA2 - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_002004 883113.HMPREF9708_00625 1.28e-161 459.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,27DMK@186827|Aerococcaceae 91061|Bacilli P ABC transporter, permease protein oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_002005 883113.HMPREF9708_00626 9.44e-178 504.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,27DBP@186827|Aerococcaceae 91061|Bacilli P ABC transporter, permease protein oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N gnl|extdb|FAM24227-i1-1.1_002006 883113.HMPREF9708_00627 5.68e-178 504.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,27DRA@186827|Aerococcaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_002007 1121871.AUAT01000011_gene522 2.95e-141 407.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,27DMC@186827|Aerococcaceae 91061|Bacilli P ABC transporter, ATP-binding protein oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_002008 1408438.JADD01000034_gene478 2.8e-182 531.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,27DTW@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1002) - - - - - - - - - - - - DUF1002,DUF4767 gnl|extdb|FAM24227-i1-1.1_002009 1265845.PWEIH_00430 3.22e-31 114.0 COG4308@1|root,COG4308@2|Bacteria 2|Bacteria Q Limonene-1,2-epoxide hydrolase catalytic domain - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2,SnoaL_2 gnl|extdb|FAM24227-i1-1.1_002010 1423815.BACR01000010_gene622 7.29e-53 170.0 COG3613@1|root,COG3613@2|Bacteria,1VB16@1239|Firmicutes,4IFT1@91061|Bacilli,3F6YF@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base - - - - - - - - - - - - Nuc_deoxyrib_tr gnl|extdb|FAM24227-i1-1.1_002013 655812.HMPREF0061_0453 1.76e-75 236.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,27ER0@186827|Aerococcaceae 91061|Bacilli M Chain length determinant protein epsB - - - - - - - - - - - GNVR,Wzz gnl|extdb|FAM24227-i1-1.1_002014 655812.HMPREF0061_0452 1.17e-93 281.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,27EP2@186827|Aerococcaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA gnl|extdb|FAM24227-i1-1.1_002016 1123500.ATUU01000004_gene1109 2.37e-10 61.6 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,4AXA0@81850|Leuconostocaceae 91061|Bacilli GM Capsular polysaccharide biosynthesis protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - gnl|extdb|FAM24227-i1-1.1_002017 655812.HMPREF0061_1831 1.88e-116 337.0 COG2148@1|root,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,4HAF1@91061|Bacilli,27EXS@186827|Aerococcaceae 91061|Bacilli M Bacterial sugar transferase capM - - ko:K13012 - - - - ko00000,ko01005 - - - Bac_transf gnl|extdb|FAM24227-i1-1.1_002018 655812.HMPREF0061_1832 1.62e-112 333.0 COG0451@1|root,COG0451@2|Bacteria,1V1S9@1239|Firmicutes,4HDRB@91061|Bacilli,27EVV@186827|Aerococcaceae 91061|Bacilli M NAD dependent epimerase dehydratase family protein cap5N - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,RmlD_sub_bind gnl|extdb|FAM24227-i1-1.1_002019 315730.BcerKBAB4_5067 1.54e-112 339.0 COG0438@1|root,COG0438@2|Bacteria,1UBE1@1239|Firmicutes,4HCY8@91061|Bacilli,1ZHMJ@1386|Bacillus 91061|Bacilli M Glycosyl transferase 4-like - - - ko:K13004 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - Glyco_trans_4_2,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_002020 1345023.M467_10530 1.29e-246 685.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,3WFGU@539002|Bacillales incertae sedis 91061|Bacilli M UDP-glucose GDP-mannose dehydrogenase - - - ko:K02474 ko00520,map00520 - R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N gnl|extdb|FAM24227-i1-1.1_002021 994573.T472_0204645 8.67e-196 547.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,36F9F@31979|Clostridiaceae 186801|Clostridia GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - 5.1.3.2,5.1.3.20,5.1.3.7 ko:K01784,ko:K02473,ko:K03274 ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100 M00064,M00361,M00362,M00632 R00291,R00418,R02984,R05176 RC00289,RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase,GDP_Man_Dehyd gnl|extdb|FAM24227-i1-1.1_002022 536227.CcarbDRAFT_3651 2.17e-132 390.0 COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,36IK4@31979|Clostridiaceae 186801|Clostridia M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_002023 518637.EUBIFOR_00107 2.61e-60 206.0 COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,3VQQY@526524|Erysipelotrichia 526524|Erysipelotrichia M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 gnl|extdb|FAM24227-i1-1.1_002024 933115.GPDM_03005 6.57e-27 107.0 COG1045@1|root,COG1045@2|Bacteria,1VD7R@1239|Firmicutes,4HYK3@91061|Bacilli 91061|Bacilli E Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep gnl|extdb|FAM24227-i1-1.1_002025 1235755.ANAM01000003_gene789 7.01e-74 244.0 COG1807@1|root,COG1807@2|Bacteria,1VDYT@1239|Firmicutes,4HN3A@91061|Bacilli,4H113@90964|Staphylococcaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002026 883113.HMPREF9708_00473 1.7e-121 370.0 COG2244@1|root,COG2244@2|Bacteria,1UY3W@1239|Firmicutes,4HEKE@91061|Bacilli,27EFW@186827|Aerococcaceae 91061|Bacilli S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C gnl|extdb|FAM24227-i1-1.1_002011 697329.Rumal_3428 8.77e-89 270.0 COG1484@1|root,COG1484@2|Bacteria,1TRWF@1239|Firmicutes,24FIP@186801|Clostridia,3WJT5@541000|Ruminococcaceae 186801|Clostridia L PFAM IstB domain protein ATP-binding protein istB2 - - - - - - - - - - - IstB_IS21 gnl|extdb|FAM24227-i1-1.1_002027 1121865.OMW_01250 9.67e-127 377.0 COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,4HDE3@91061|Bacilli,4B0BK@81852|Enterococcaceae 91061|Bacilli GK ROK family xylR - - - - - - - - - - - HTH_24,MarR,ROK gnl|extdb|FAM24227-i1-1.1_002028 1121865.OMW_01249 1.57e-235 657.0 COG2115@1|root,COG2115@2|Bacteria,1TQW2@1239|Firmicutes,4H9WG@91061|Bacilli,4B1PJ@81852|Enterococcaceae 91061|Bacilli G Belongs to the xylose isomerase family xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 gnl|extdb|FAM24227-i1-1.1_002029 1123315.AUIP01000023_gene1161 7.95e-215 609.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4HBRJ@91061|Bacilli 91061|Bacilli G xylulose kinase xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU17610 FGGY_C,FGGY_N gnl|extdb|FAM24227-i1-1.1_002030 272563.CD630_30710 0.0 1067.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia 186801|Clostridia G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.177 ko:K01811 - - - - ko00000,ko01000 - GH31 - DUF5110,Glyco_hydro_31 gnl|extdb|FAM24227-i1-1.1_002031 879305.HMPREF9290_0727 6.39e-224 647.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,22IQ4@1570339|Peptoniphilaceae 186801|Clostridia G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.177 ko:K01811 - - - - ko00000,ko01000 - GH31 - DUF5110,Glyco_hydro_31 gnl|extdb|FAM24227-i1-1.1_002032 1158607.UAU_00768 5.04e-64 200.0 COG3444@1|root,COG3444@2|Bacteria,1V8BP@1239|Firmicutes,4I36N@91061|Bacilli,4B3M7@81852|Enterococcaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - - - - - - - - - - - PTSIIB_sorb gnl|extdb|FAM24227-i1-1.1_002033 879305.HMPREF9290_0725 2.55e-122 356.0 COG3715@1|root,COG3715@2|Bacteria,1TSJD@1239|Firmicutes,25C3D@186801|Clostridia 186801|Clostridia G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor gnl|extdb|FAM24227-i1-1.1_002035 879305.HMPREF9290_0723 8.1e-45 150.0 COG2893@1|root,COG2893@2|Bacteria,1VG8P@1239|Firmicutes,24QR2@186801|Clostridia,22HZQ@1570339|Peptoniphilaceae 186801|Clostridia G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man gnl|extdb|FAM24227-i1-1.1_002036 1321778.HMPREF1982_00855 8.65e-271 775.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia 186801|Clostridia G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - DUF4968,DUF5110,Glyco_hydro_31 gnl|extdb|FAM24227-i1-1.1_002037 908337.HMPREF9257_1412 1.72e-121 356.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,27DS1@186827|Aerococcaceae 91061|Bacilli I NAD binding domain protein glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 gnl|extdb|FAM24227-i1-1.1_002039 866775.HMPREF9243_0303 1.21e-19 86.7 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli 91061|Bacilli S phosphatase phosphohexomutase - - - - - - - - - - - - HAD_2 gnl|extdb|FAM24227-i1-1.1_002040 1123308.KB904550_gene383 2.07e-16 79.0 COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,4HKIV@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant 3 - - - - - - - - - - - - HAD_2 gnl|extdb|FAM24227-i1-1.1_002034 879305.HMPREF9290_0724 2.93e-132 382.0 COG3716@1|root,COG3716@2|Bacteria,1TSQF@1239|Firmicutes,249FW@186801|Clostridia,22IGH@1570339|Peptoniphilaceae 186801|Clostridia G PTS system mannose/fructose/sorbose family IID component - - - ko:K02747 ko00052,ko02060,map00052,map02060 M00277 R08366 RC00017 ko00000,ko00001,ko00002,ko02000 4.A.6.1.4 - - EIID-AGA gnl|extdb|FAM24227-i1-1.1_002038 866775.HMPREF9243_0303 8.38e-32 121.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli 91061|Bacilli S phosphatase phosphohexomutase - - - - - - - - - - - - HAD_2 gnl|extdb|FAM24227-i1-1.1_002042 908337.HMPREF9257_0188 1.54e-118 349.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,27DQ0@186827|Aerococcaceae 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation - - - - - - - - - - - - FtsX gnl|extdb|FAM24227-i1-1.1_002043 1408438.JADD01000013_gene1698 3.63e-112 327.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,27DEX@186827|Aerococcaceae 91061|Bacilli D ABC transporter ftsE GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_002044 1408438.JADD01000013_gene1697 1.66e-181 513.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,27DIP@186827|Aerococcaceae 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 gnl|extdb|FAM24227-i1-1.1_002045 883112.HMPREF9707_01056 0.0 1335.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,27DGQ@186827|Aerococcaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW gnl|extdb|FAM24227-i1-1.1_002046 1408438.JADD01000013_gene1695 4.74e-98 288.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,27DPM@186827|Aerococcaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE gnl|extdb|FAM24227-i1-1.1_002047 883112.HMPREF9707_00067 2.9e-76 236.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,27DRD@186827|Aerococcaceae 91061|Bacilli P TrkA-N domain ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N gnl|extdb|FAM24227-i1-1.1_002048 883112.HMPREF9707_00066 1.01e-164 478.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,27DVA@186827|Aerococcaceae 91061|Bacilli P Cation transport protein ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH gnl|extdb|FAM24227-i1-1.1_002050 1408438.JADD01000013_gene1694 8.7e-70 222.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,27E2R@186827|Aerococcaceae 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran gnl|extdb|FAM24227-i1-1.1_002052 1122129.AUEF01000012_gene1173 3.08e-63 200.0 COG0431@1|root,COG0431@2|Bacteria,1TPDX@1239|Firmicutes,4HE2D@91061|Bacilli,4GYYI@90964|Staphylococcaceae 91061|Bacilli S NADPH-dependent FMN reductase - - 1.5.1.38 ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 - R05706,R07210,R10206 RC00126,RC01779,RC02556 ko00000,ko00001,ko01000 - - iSB619.SA_RS01880 FMN_red gnl|extdb|FAM24227-i1-1.1_002053 1461582.BN1048_01792 5.36e-168 479.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,4GY62@90964|Staphylococcaceae 91061|Bacilli C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase gnl|extdb|FAM24227-i1-1.1_002054 866775.HMPREF9243_0930 1.19e-148 430.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase gnl|extdb|FAM24227-i1-1.1_002055 883112.HMPREF9707_00063 2.59e-91 279.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,27DX6@186827|Aerococcaceae 91061|Bacilli S EDD domain protein, DegV family XK27_08360 - - - - - - - - - - - DegV gnl|extdb|FAM24227-i1-1.1_002056 1408438.JADD01000013_gene1690 8.37e-91 272.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,27DXR@186827|Aerococcaceae 91061|Bacilli S Uncharacterized protein family UPF0029 yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 gnl|extdb|FAM24227-i1-1.1_002057 883112.HMPREF9707_00061 4.2e-98 296.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,27DX6@186827|Aerococcaceae 91061|Bacilli S EDD domain protein, DegV family XK27_08360 - - - - - - - - - - - DegV gnl|extdb|FAM24227-i1-1.1_002051 1408438.JADD01000013_gene1693 2.45e-176 508.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,27DIK@186827|Aerococcaceae 91061|Bacilli L helicase superfamily c-terminal domain comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII gnl|extdb|FAM24227-i1-1.1_002059 1121871.AUAT01000005_gene1724 0.0 1207.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,27DTH@186827|Aerococcaceae 91061|Bacilli O ATPase family associated with various cellular activities (AAA) clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR gnl|extdb|FAM24227-i1-1.1_002060 883110.HMPREF9260_01718 1.77e-66 206.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,27DWW@186827|Aerococcaceae 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR gnl|extdb|FAM24227-i1-1.1_002061 655812.HMPREF0061_0458 2.09e-115 350.0 COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,4HGFS@91061|Bacilli,27EB3@186827|Aerococcaceae 91061|Bacilli S AI-2E family transporter XK27_12525 - - - - - - - - - - - AI-2E_transport gnl|extdb|FAM24227-i1-1.1_002062 1408438.JADD01000005_gene1242 4.02e-97 299.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002063 1123230.ARQJ01000025_gene2419 1.13e-79 240.0 COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,4HIHC@91061|Bacilli 91061|Bacilli L phosphatase homologous to the C-terminal domain of histone macroH2A1 ymdB - - - - - - - - - - - Macro gnl|extdb|FAM24227-i1-1.1_002064 575594.ACOH01000003_gene669 8.9e-76 234.0 COG2231@1|root,COG2231@2|Bacteria,1V4SG@1239|Firmicutes,4HI5U@91061|Bacilli,3F62T@33958|Lactobacillaceae 91061|Bacilli L Base excision DNA repair protein, HhH-GPD family nth2 - - ko:K07457 - - - - ko00000 - - - HhH-GPD gnl|extdb|FAM24227-i1-1.1_002065 1121871.AUAT01000032_gene475 6.03e-170 508.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,27DU5@186827|Aerococcaceae 91061|Bacilli V FtsX-like permease family XK27_05700 - - ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - FtsX gnl|extdb|FAM24227-i1-1.1_002066 908337.HMPREF9257_0496 3.26e-113 332.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,27DKK@186827|Aerococcaceae 91061|Bacilli V ATPases associated with a variety of cellular activities XK27_05695 - - ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_002067 458233.MCCL_0281 1.3e-86 266.0 COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HGDC@91061|Bacilli,4H19P@90964|Staphylococcaceae 91061|Bacilli T Histidine kinase nsaS - 2.7.13.3 ko:K19081 ko02020,map02020 M00734,M00737 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c gnl|extdb|FAM24227-i1-1.1_002068 1121871.AUAT01000032_gene471 2.24e-92 277.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,27DWS@186827|Aerococcaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal graR - - ko:K19082 ko02020,map02020 M00734,M00737 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C gnl|extdb|FAM24227-i1-1.1_002069 1123359.AUIQ01000025_gene28 3.42e-219 617.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli 91061|Bacilli E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 gnl|extdb|FAM24227-i1-1.1_002070 908337.HMPREF9257_1511 1.95e-187 543.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,27DNE@186827|Aerococcaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_002058 655812.HMPREF0061_1458 8.06e-109 325.0 COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes 1239|Firmicutes S Transporter, auxin efflux carrier (AEC) family protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans gnl|extdb|FAM24227-i1-1.1_002071 592010.GCWU000182_000914 1.05e-237 663.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,27DCB@186827|Aerococcaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N gnl|extdb|FAM24227-i1-1.1_002074 1122143.AUEG01000003_gene916 2.71e-05 44.3 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_002075 883112.HMPREF9707_00722 1.62e-31 122.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,27EK6@186827|Aerococcaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_002076 873449.STRCR_0488 1.54e-253 704.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh gnl|extdb|FAM24227-i1-1.1_002077 1160707.AJIK01000003_gene737 2.97e-154 448.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli,26EQX@186818|Planococcaceae 91061|Bacilli C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) acoC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding gnl|extdb|FAM24227-i1-1.1_002078 866775.HMPREF9243_1526 1.89e-204 570.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit acoB - - ko:K21417 - - - - ko00000,ko01000 - - - Transket_pyr,Transketolase_C gnl|extdb|FAM24227-i1-1.1_002079 1160707.AJIK01000003_gene735 9.41e-192 539.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli,26DM3@186818|Planococcaceae 91061|Bacilli C dehydrogenase E1 component acoA - - ko:K21416 - - - - ko00000,ko01000 - - - E1_dh gnl|extdb|FAM24227-i1-1.1_002080 699248.SRA_06251 7.29e-183 525.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli 91061|Bacilli C Dehydrogenase pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim gnl|extdb|FAM24227-i1-1.1_002081 1160707.AJIK01000003_gene733 0.0 920.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,26E4B@186818|Planococcaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N gnl|extdb|FAM24227-i1-1.1_002082 1121864.OMO_00264 7.75e-120 365.0 COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,4HUF7@91061|Bacilli,4B1RJ@81852|Enterococcaceae 91061|Bacilli K Bacterial regulatory protein, Fis family acoR - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat gnl|extdb|FAM24227-i1-1.1_002083 1121105.ATXL01000005_gene182 7.8e-51 181.0 COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,4HUF7@91061|Bacilli,4B1RJ@81852|Enterococcaceae 91061|Bacilli K Bacterial regulatory protein, Fis family acoR - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat gnl|extdb|FAM24227-i1-1.1_002072 556261.HMPREF0240_00696 1.71e-113 335.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,36EBG@31979|Clostridiaceae 186801|Clostridia E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase gnl|extdb|FAM24227-i1-1.1_002073 1280688.AUJB01000015_gene429 1.37e-188 535.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3NHHR@46205|Pseudobutyrivibrio 186801|Clostridia E Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate dapL - 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_002084 1336234.JAGN01000025_gene729 8.63e-15 68.6 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3 gnl|extdb|FAM24227-i1-1.1_002085 883113.HMPREF9708_00087 2.64e-209 602.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27DQN@186827|Aerococcaceae 91061|Bacilli V ABC transporter transmembrane region yheI - - ko:K18216,ko:K18889 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_002086 883113.HMPREF9708_00086 8.71e-230 654.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27DFI@186827|Aerococcaceae 91061|Bacilli V ABC transporter transmembrane region yheH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K18217,ko:K18890 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_002087 883112.HMPREF9707_00454 6.06e-111 325.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HFDZ@91061|Bacilli,27DG3@186827|Aerococcaceae 91061|Bacilli G Phosphoglycerate mutase family pgm3 - - - - - - - - - - - His_Phos_1 gnl|extdb|FAM24227-i1-1.1_002088 1121871.AUAT01000001_gene820 5.85e-114 339.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,27ED2@186827|Aerococcaceae 91061|Bacilli S Belongs to the UPF0761 family - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB gnl|extdb|FAM24227-i1-1.1_002089 883112.HMPREF9707_00456 9.64e-200 563.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,27DC0@186827|Aerococcaceae 91061|Bacilli D Cell cycle protein, FtsW RodA SpoVE family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE gnl|extdb|FAM24227-i1-1.1_002091 1408438.JADD01000022_gene66 3.37e-107 323.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,27E1H@186827|Aerococcaceae 91061|Bacilli L DNA polymerase III, delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta gnl|extdb|FAM24227-i1-1.1_002092 1408438.JADD01000022_gene67 8.04e-21 85.5 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,27E8M@186827|Aerococcaceae 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p gnl|extdb|FAM24227-i1-1.1_002093 1408438.JADD01000022_gene69 0.0 1102.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,27DSI@186827|Aerococcaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB gnl|extdb|FAM24227-i1-1.1_002094 883112.HMPREF9707_00461 1.81e-257 733.0 COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli 91061|Bacilli I Acyltransferase oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 gnl|extdb|FAM24227-i1-1.1_002095 1121105.ATXL01000011_gene1940 7.15e-48 154.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,4B309@81852|Enterococcaceae 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 gnl|extdb|FAM24227-i1-1.1_002096 883112.HMPREF9707_00463 0.0 1070.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,27DJ7@186827|Aerococcaceae 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 gnl|extdb|FAM24227-i1-1.1_002097 1336234.JAGN01000025_gene729 8.63e-15 68.6 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3 gnl|extdb|FAM24227-i1-1.1_002090 883112.HMPREF9707_00457 1.64e-27 102.0 COG0509@1|root,COG0509@2|Bacteria,1VAMB@1239|Firmicutes,4I62X@91061|Bacilli,27EVQ@186827|Aerococcaceae 91061|Bacilli E Glycine cleavage H-protein - - - - - - - - - - - - GCV_H gnl|extdb|FAM24227-i1-1.1_002098 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002099 1123290.AUDQ01000007_gene2083 1.8e-136 393.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HACK@91061|Bacilli,26D3F@186818|Planococcaceae 91061|Bacilli S Aldo/keto reductase family dkgB - - - - - - - - - - - Aldo_ket_red gnl|extdb|FAM24227-i1-1.1_002100 485913.Krac_5451 0.000113 44.7 2DQ3G@1|root,334K8@2|Bacteria,2G77Z@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF2568) - - - - - - - - - - - - DUF2568 gnl|extdb|FAM24227-i1-1.1_002101 698758.AXY_17360 2.53e-223 681.0 COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal gnl|extdb|FAM24227-i1-1.1_002102 1382305.AZUC01000013_gene2809 9.49e-30 127.0 COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,4HHE1@91061|Bacilli 91061|Bacilli O Belongs to the serpin family - - - ko:K13963 ko05146,map05146 - - - ko00000,ko00001 - - - Serpin gnl|extdb|FAM24227-i1-1.1_002103 1121871.AUAT01000005_gene1759 7.85e-66 218.0 COG2367@1|root,COG2367@2|Bacteria,1V9PM@1239|Firmicutes,4I6BS@91061|Bacilli,27E0P@186827|Aerococcaceae 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 gnl|extdb|FAM24227-i1-1.1_002104 883112.HMPREF9707_00285 1.8e-71 223.0 COG2755@1|root,COG2755@2|Bacteria,1V2BU@1239|Firmicutes,4HFRU@91061|Bacilli 91061|Bacilli E G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 gnl|extdb|FAM24227-i1-1.1_002105 997296.PB1_04105 2.83e-37 131.0 COG3238@1|root,COG3238@2|Bacteria,1V6IR@1239|Firmicutes,4HI8A@91061|Bacilli,1ZH6I@1386|Bacillus 91061|Bacilli S Putative inner membrane exporter, YdcZ - - - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ gnl|extdb|FAM24227-i1-1.1_002106 1232430.CAVG010000154_gene1615 2.08e-99 307.0 COG0560@1|root,COG0560@2|Bacteria,1UW6W@1239|Firmicutes,4HF7Y@91061|Bacilli 91061|Bacilli E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD gnl|extdb|FAM24227-i1-1.1_002107 1121871.AUAT01000023_gene1063 1.77e-65 206.0 COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,4HM36@91061|Bacilli,27E6N@186827|Aerococcaceae 91061|Bacilli S DJ-1/PfpI family thiJ - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI gnl|extdb|FAM24227-i1-1.1_002108 883112.HMPREF9707_00286 2.61e-78 245.0 COG4990@1|root,COG4990@2|Bacteria,1VDCP@1239|Firmicutes,4HNSJ@91061|Bacilli,27EES@186827|Aerococcaceae 91061|Bacilli S Papain-like cysteine protease AvrRpt2 - - - - - - - - - - - - Amidase_3,Peptidase_C39_2,SH3_3 gnl|extdb|FAM24227-i1-1.1_002109 634994.GCWU000323_02765 6.32e-64 199.0 COG0394@1|root,COG0394@2|Bacteria,37CG2@32066|Fusobacteria 32066|Fusobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc gnl|extdb|FAM24227-i1-1.1_002110 1121024.AUCD01000024_gene765 9.98e-114 335.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,27G1J@186828|Carnobacteriaceae 91061|Bacilli E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase gnl|extdb|FAM24227-i1-1.1_002111 1122143.AUEG01000021_gene1215 2.38e-196 556.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,27FNJ@186828|Carnobacteriaceae 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh gnl|extdb|FAM24227-i1-1.1_002112 1121024.AUCD01000038_gene437 3.34e-116 349.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,27FY0@186828|Carnobacteriaceae 91061|Bacilli P Cation efflux family czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux gnl|extdb|FAM24227-i1-1.1_002113 1408438.JADD01000005_gene1229 3.82e-206 583.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,27DH6@186827|Aerococcaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 gnl|extdb|FAM24227-i1-1.1_002114 1266845.Q783_09980 2.24e-29 111.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002115 1158612.I580_01300 1.26e-73 230.0 COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,4IQ6M@91061|Bacilli,4B2P3@81852|Enterococcaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg gnl|extdb|FAM24227-i1-1.1_002116 1158607.UAU_00281 4e-110 338.0 COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,4IIXD@91061|Bacilli,4B049@81852|Enterococcaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c_5 gnl|extdb|FAM24227-i1-1.1_002117 1308866.J416_12779 0.0 1035.0 COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,4HA45@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C gnl|extdb|FAM24227-i1-1.1_002118 1123359.AUIQ01000018_gene252 0.0 965.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HCAH@91061|Bacilli,4B3XN@81852|Enterococcaceae 91061|Bacilli G Glycosyl hydrolase family 3 C-terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Glyco_hydro_3,Glyco_hydro_3_C gnl|extdb|FAM24227-i1-1.1_002121 592010.GCWU000182_001590 2.95e-117 349.0 COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,4H9Q4@91061|Bacilli 91061|Bacilli M Glycosyltransferase like family 2 XK27_01805 - - - - - - - - - - - Glycos_transf_2 gnl|extdb|FAM24227-i1-1.1_002122 585203.SMSK564_1742 8.17e-201 563.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,2TPGY@28037|Streptococcus mitis 91061|Bacilli M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 gnl|extdb|FAM24227-i1-1.1_002123 1175629.AJTG01000031_gene1604 3.01e-26 107.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,27ECN@186827|Aerococcaceae 91061|Bacilli L Protein of unknown function (DUF1722) uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - DUF1722,UvdE gnl|extdb|FAM24227-i1-1.1_002124 398512.JQKC01000012_gene243 4.13e-15 76.6 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,24BHY@186801|Clostridia,3WNSC@541000|Ruminococcaceae 186801|Clostridia L PFAM UV-endonuclease UvdE uvdE - - ko:K13281 - - - - ko00000,ko01000 - - - DUF1722,UvdE gnl|extdb|FAM24227-i1-1.1_002125 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002120 391295.SSU05_2146 3.13e-81 244.0 28NMC@1|root,32YYJ@2|Bacteria,1UPWH@1239|Firmicutes 1239|Firmicutes S GtrA-like protein - - - - - - - - - - - - GtrA gnl|extdb|FAM24227-i1-1.1_002119 1158610.UC3_02752 1.14e-315 890.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,4AZJE@81852|Enterococcaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family bglB - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C gnl|extdb|FAM24227-i1-1.1_002127 565655.ECBG_02727 8.69e-59 187.0 COG0454@1|root,COG0456@2|Bacteria,1V1RG@1239|Firmicutes,4HFN7@91061|Bacilli,4B31W@81852|Enterococcaceae 91061|Bacilli K Protease synthase and sporulation negative regulatory protein pai 1 paiA - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 gnl|extdb|FAM24227-i1-1.1_002130 883110.HMPREF9260_01777 3.25e-116 363.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,27DH5@186827|Aerococcaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_002134 883114.HMPREF9709_01337 1.11e-10 69.3 COG1396@1|root,COG1396@2|Bacteria,1V9U4@1239|Firmicutes,257IM@186801|Clostridia 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002136 1408438.JADD01000029_gene1367 0.0 910.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,27ECC@186827|Aerococcaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB gnl|extdb|FAM24227-i1-1.1_002137 1408438.JADD01000029_gene1368 1.09e-128 375.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,27EKR@186827|Aerococcaceae 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB gnl|extdb|FAM24227-i1-1.1_002138 638301.HMPREF0444_1607 8.08e-82 252.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,27G4V@186828|Carnobacteriaceae 91061|Bacilli K DeoR C terminal sensor domain fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR gnl|extdb|FAM24227-i1-1.1_002139 883103.HMPREF9703_01687 1.55e-39 145.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,27G88@186828|Carnobacteriaceae 91061|Bacilli E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 gnl|extdb|FAM24227-i1-1.1_002140 1179226.AJXO01000040_gene2002 1.37e-17 81.6 COG2364@1|root,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,4HG9V@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002141 1229520.ADIAL_2021 6.03e-198 558.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,27FJJ@186828|Carnobacteriaceae 91061|Bacilli C 4Fe-4S double cluster binding domain queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 gnl|extdb|FAM24227-i1-1.1_002144 1408438.JADD01000011_gene1613 7.38e-270 744.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,27DR2@186827|Aerococcaceae 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI gnl|extdb|FAM24227-i1-1.1_002145 592010.GCWU000182_001644 1.89e-53 171.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,27E24@186827|Aerococcaceae 91061|Bacilli J S1 RNA binding domain yugI - - ko:K07570 - - - - ko00000 - - - S1 gnl|extdb|FAM24227-i1-1.1_002146 1408438.JADD01000011_gene1611 9.2e-99 291.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,27DTP@186827|Aerococcaceae 91061|Bacilli O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase gnl|extdb|FAM24227-i1-1.1_002147 883112.HMPREF9707_01590 6.5e-62 196.0 COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,4HHA6@91061|Bacilli,27E37@186827|Aerococcaceae 91061|Bacilli S Divergent PAP2 family yuiD - - ko:K09775 - - - - ko00000 - - - DUF212 gnl|extdb|FAM24227-i1-1.1_002148 1408438.JADD01000011_gene1609 1.45e-153 441.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,27DNW@186827|Aerococcaceae 91061|Bacilli C L-lysine 6-monooxygenase (NADPH-requiring) yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 gnl|extdb|FAM24227-i1-1.1_002149 1408438.JADD01000011_gene1608 9.95e-89 265.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,27ENF@186827|Aerococcaceae 91061|Bacilli I Phosphatidylglycerophosphatase A pgpA - - - - - - - - - - - PgpA gnl|extdb|FAM24227-i1-1.1_002150 1408438.JADD01000011_gene1607 1.44e-45 157.0 COG4478@1|root,COG4478@2|Bacteria,1V7UW@1239|Firmicutes,4HHBQ@91061|Bacilli,27F3H@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1461) ylfI - - - - - - - - - - - DUF1461 gnl|extdb|FAM24227-i1-1.1_002151 1408438.JADD01000011_gene1606 2.05e-97 292.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,27DTK@186827|Aerococcaceae 91061|Bacilli G Haloacid dehalogenase-like hydrolase nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like gnl|extdb|FAM24227-i1-1.1_002152 592010.GCWU000182_001651 2.38e-45 157.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,27E5J@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF1027) yutD - - - - - - - - - - - DUF1027 gnl|extdb|FAM24227-i1-1.1_002153 908337.HMPREF9257_0310 1.32e-165 481.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,27DU8@186827|Aerococcaceae 91061|Bacilli F Calcineurin-like phosphoesterase yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos gnl|extdb|FAM24227-i1-1.1_002154 883112.HMPREF9707_01585 3.77e-43 150.0 COG1183@1|root,COG1183@2|Bacteria,1TX6N@1239|Firmicutes,4I634@91061|Bacilli,27EXA@186827|Aerococcaceae 91061|Bacilli I phosphatidylcholine synthase activity - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002155 592010.GCWU000182_000531 5.26e-105 313.0 COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,4HC4E@91061|Bacilli,27DFQ@186827|Aerococcaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 yitS - - - - - - - - - - - DegV gnl|extdb|FAM24227-i1-1.1_002156 883112.HMPREF9707_01583 1.42e-64 217.0 COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes 1239|Firmicutes I Alpha Beta - - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 gnl|extdb|FAM24227-i1-1.1_002158 1408438.JADD01000011_gene1596 8.63e-136 393.0 COG0726@1|root,COG0726@2|Bacteria,1TS3D@1239|Firmicutes,4HAVF@91061|Bacilli,27E0I@186827|Aerococcaceae 91061|Bacilli G Polysaccharide deacetylase pdaA_2 - 3.5.1.104 ko:K01567,ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 gnl|extdb|FAM24227-i1-1.1_002159 883113.HMPREF9708_01129 2.68e-37 134.0 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli 91061|Bacilli M acetyltransferase pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 gnl|extdb|FAM24227-i1-1.1_002162 1450694.BTS2_2403 5.87e-32 114.0 COG2963@1|root,COG2963@2|Bacteria,1VP6M@1239|Firmicutes,4HRHX@91061|Bacilli,1ZIZ1@1386|Bacillus 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 gnl|extdb|FAM24227-i1-1.1_002164 1121871.AUAT01000025_gene1192 2.12e-280 783.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,27EAP@186827|Aerococcaceae 91061|Bacilli C hmm pf01266 - - - - - - - - - - - - FAD_binding_2,FMN_bind gnl|extdb|FAM24227-i1-1.1_002165 491915.Aflv_2434 7.6e-33 116.0 COG2963@1|root,COG2963@2|Bacteria,1VIEV@1239|Firmicutes,4HJSC@91061|Bacilli,21X3B@150247|Anoxybacillus 91061|Bacilli L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 gnl|extdb|FAM24227-i1-1.1_002166 1033733.CAEK01000002_gene92 4.85e-09 60.8 29PCN@1|root,30AAW@2|Bacteria,1V1IN@1239|Firmicutes,25NK1@186801|Clostridia,22IFZ@1570339|Peptoniphilaceae 186801|Clostridia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002167 1336234.JAGN01000042_gene487 1.16e-50 171.0 2ADW4@1|root,313N4@2|Bacteria,1V790@1239|Firmicutes,4HQX4@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF4230) - - - - - - - - - - - - DUF4230 gnl|extdb|FAM24227-i1-1.1_002171 1139996.OMQ_02035 2.89e-77 233.0 COG1764@1|root,COG1764@2|Bacteria,1V7KG@1239|Firmicutes,4HJ7U@91061|Bacilli,4B6IK@81852|Enterococcaceae 91061|Bacilli O OsmC-like protein ohr - - - - - - - - - - - OsmC gnl|extdb|FAM24227-i1-1.1_002172 1139996.OMQ_02034 1.41e-77 239.0 COG0664@1|root,COG0664@2|Bacteria,1TTDI@1239|Firmicutes,4I42J@91061|Bacilli,4B52B@81852|Enterococcaceae 91061|Bacilli K Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - HTH_Crp_2,cNMP_binding gnl|extdb|FAM24227-i1-1.1_002174 1158601.I585_01334 5.87e-50 160.0 COG3414@1|root,COG3414@2|Bacteria 2|Bacteria G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB gnl|extdb|FAM24227-i1-1.1_002175 1158601.I585_01333 1.74e-243 676.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HA1Q@91061|Bacilli,4AZER@81852|Enterococcaceae 91061|Bacilli G PTS system sugar-specific permease component - - - - - - - - - - - - EIIC-GAT gnl|extdb|FAM24227-i1-1.1_002176 1266845.Q783_09980 2.24e-29 111.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002163 558169.AGAV01000003_gene2893 1.59e-76 236.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli 91061|Bacilli L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve gnl|extdb|FAM24227-i1-1.1_002177 883112.HMPREF9707_00489 5.23e-292 813.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,27EAG@186827|Aerococcaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA1 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_002178 1408438.JADD01000023_gene9 5.43e-92 276.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,27DUK@186827|Aerococcaceae 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm gnl|extdb|FAM24227-i1-1.1_002179 883112.HMPREF9707_00491 7.29e-306 894.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,27DS5@186827|Aerococcaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge gnl|extdb|FAM24227-i1-1.1_002180 592010.GCWU000182_000096 1.34e-88 271.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HCEA@91061|Bacilli,27DZZ@186827|Aerococcaceae 91061|Bacilli S Cof-like hydrolase - - - - - - - - - - - - Hydrolase_3 gnl|extdb|FAM24227-i1-1.1_002181 592010.GCWU000182_000095 5.5e-179 506.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,27DHJ@186827|Aerococcaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N gnl|extdb|FAM24227-i1-1.1_002183 655812.HMPREF0061_1058 9.2e-79 248.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HCDH@91061|Bacilli,27DY0@186827|Aerococcaceae 91061|Bacilli P ABC 3 transport family mntC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 M00318,M00319,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15,3.A.1.15.6 - - ABC-3 gnl|extdb|FAM24227-i1-1.1_002184 1121871.AUAT01000007_gene1675 4.65e-79 245.0 COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli,27DWI@186827|Aerococcaceae 91061|Bacilli P ATPases associated with a variety of cellular activities mntB - 3.6.3.35 ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 M00243,M00244,M00319,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15 - iYO844.BSU30760 ABC_tran gnl|extdb|FAM24227-i1-1.1_002185 908337.HMPREF9257_0376 4.2e-95 290.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,27DEA@186827|Aerococcaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family troA - - ko:K11707 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA gnl|extdb|FAM24227-i1-1.1_002186 1121871.AUAT01000007_gene1673 2.47e-46 157.0 COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HI7T@91061|Bacilli,27E66@186827|Aerococcaceae 91061|Bacilli K Helix-turn-helix diphteria tox regulatory element mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA gnl|extdb|FAM24227-i1-1.1_002187 1121871.AUAT01000001_gene780 2.8e-248 694.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,27DQ4@186827|Aerococcaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB gnl|extdb|FAM24227-i1-1.1_002188 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002182 908337.HMPREF9257_0379 2.79e-82 256.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,27DY3@186827|Aerococcaceae 91061|Bacilli P ABC 3 transport family mntD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11709,ko:K19976 ko02010,map02010 M00319,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15 - - ABC-3 gnl|extdb|FAM24227-i1-1.1_002189 655812.HMPREF0061_1734 0.0 993.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,27ECE@186827|Aerococcaceae 91061|Bacilli C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain spxB - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N gnl|extdb|FAM24227-i1-1.1_002190 1536773.R70331_23030 0.000432 44.7 COG1846@1|root,COG1846@2|Bacteria,1V1U2@1239|Firmicutes,4HGE4@91061|Bacilli,26RX6@186822|Paenibacillaceae 91061|Bacilli K MarR family transcriptional regulator - - - - - - - - - - - - MarR gnl|extdb|FAM24227-i1-1.1_002191 655812.HMPREF0061_1780 2.03e-271 744.0 COG0446@1|root,COG0446@2|Bacteria,1TRNN@1239|Firmicutes,4HE8X@91061|Bacilli 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Reductase_C gnl|extdb|FAM24227-i1-1.1_002192 1408438.JADD01000049_gene868 1.6e-125 358.0 COG4300@1|root,COG4300@2|Bacteria,1TPQX@1239|Firmicutes,4HAME@91061|Bacilli,27EGB@186827|Aerococcaceae 91061|Bacilli P Cadmium resistance transporter cadD - - - - - - - - - - - Cad gnl|extdb|FAM24227-i1-1.1_002193 879212.DespoDRAFT_00360 4.73e-31 124.0 COG1404@1|root,COG1404@2|Bacteria,1ND93@1224|Proteobacteria,42NPY@68525|delta/epsilon subdivisions,2WMGV@28221|Deltaproteobacteria,2MMRI@213118|Desulfobacterales 28221|Deltaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 gnl|extdb|FAM24227-i1-1.1_002194 879212.DespoDRAFT_00360 3.58e-27 113.0 COG1404@1|root,COG1404@2|Bacteria,1ND93@1224|Proteobacteria,42NPY@68525|delta/epsilon subdivisions,2WMGV@28221|Deltaproteobacteria,2MMRI@213118|Desulfobacterales 28221|Deltaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 gnl|extdb|FAM24227-i1-1.1_002198 883103.HMPREF9703_00702 3.43e-40 138.0 COG2963@1|root,COG2963@2|Bacteria,1V35U@1239|Firmicutes,4HHRN@91061|Bacilli,27GJT@186828|Carnobacteriaceae 91061|Bacilli L Helix-turn-helix domain - - - ko:K07483,ko:K07497 - - - - ko00000 - - - HTH_28,HTH_Tnp_1 gnl|extdb|FAM24227-i1-1.1_002200 1175629.AJTG01000017_gene1694 2.24e-287 790.0 2E79A@1|root,331SV@2|Bacteria,1VYA9@1239|Firmicutes,4HXIP@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002202 227882.SAV_3724 3.34e-14 71.2 2CJRK@1|root,2ZKE1@2|Bacteria,2GY04@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002199 1158614.I592_00885 5.24e-18 78.2 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,4B2YG@81852|Enterococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA gnl|extdb|FAM24227-i1-1.1_002204 1158609.I586_01337 5.33e-67 216.0 2BBX7@1|root,325FQ@2|Bacteria,1UIYR@1239|Firmicutes,4ISXF@91061|Bacilli,4B6MV@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002205 1175629.AJTG01000002_gene1324 9.6e-161 468.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,27DPV@186827|Aerococcaceae 91061|Bacilli E Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans gnl|extdb|FAM24227-i1-1.1_002206 883081.HMPREF9698_00590 1.76e-44 150.0 2ENFB@1|root,3342N@2|Bacteria,1VIM9@1239|Firmicutes,4HR10@91061|Bacilli,27HJ1@186828|Carnobacteriaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002207 883081.HMPREF9698_00589 4.02e-132 387.0 COG0613@1|root,COG0613@2|Bacteria,1V2U3@1239|Firmicutes,4HGR8@91061|Bacilli,27H00@186828|Carnobacteriaceae 91061|Bacilli S DNA polymerase alpha chain like domain - - - - - - - - - - - - PHP gnl|extdb|FAM24227-i1-1.1_002208 596315.HMPREF0634_1316 5.73e-233 650.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,25QQE@186804|Peptostreptococcaceae 186801|Clostridia F Permease family pbuX - - ko:K03458,ko:K16345 - - - - ko00000,ko02000 2.A.40,2.A.40.4.2 - - Xan_ur_permease gnl|extdb|FAM24227-i1-1.1_002209 1219626.HMPREF1639_09230 2.91e-88 264.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,25TEU@186804|Peptostreptococcaceae 186801|Clostridia F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran gnl|extdb|FAM24227-i1-1.1_002210 1121947.AUHK01000017_gene13 9.23e-33 114.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,22HRC@1570339|Peptoniphilaceae 186801|Clostridia K DNA-binding helix-turn-helix protein - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 gnl|extdb|FAM24227-i1-1.1_002212 1121871.AUAT01000004_gene1105 1.09e-66 207.0 2B1UF@1|root,31UAF@2|Bacteria,1V4WF@1239|Firmicutes,4HI2Y@91061|Bacilli,27EQT@186827|Aerococcaceae 91061|Bacilli S An automated process has identified a potential problem with this gene model - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002213 908337.HMPREF9257_0893 5.2e-144 411.0 arCOG09719@1|root,2Z7NA@2|Bacteria,1TSE4@1239|Firmicutes,4HE46@91061|Bacilli,27EJM@186827|Aerococcaceae 91061|Bacilli S Protein of unknown function (DUF3100) - - - - - - - - - - - - DUF3100 gnl|extdb|FAM24227-i1-1.1_002215 1122149.BACN01000093_gene1673 1.02e-29 109.0 COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,3F88S@33958|Lactobacillaceae 91061|Bacilli P Rhodanese Homology Domain XK27_05625 - - - - - - - - - - - Rhodanese gnl|extdb|FAM24227-i1-1.1_002216 1033734.CAET01000038_gene73 5.1e-58 181.0 2DMTK@1|root,32TKW@2|Bacteria,1VA3N@1239|Firmicutes,4HMQA@91061|Bacilli,1ZHN3@1386|Bacillus 91061|Bacilli - - XK27_02555 - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002217 279010.BL02071 1.68e-08 55.1 COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,1ZHWJ@1386|Bacillus 91061|Bacilli M FR47-like protein M1-753 - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,FR47 gnl|extdb|FAM24227-i1-1.1_002219 592010.GCWU000182_000398 1.07e-59 191.0 COG1670@1|root,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,4HJXI@91061|Bacilli,27E78@186827|Aerococcaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 gnl|extdb|FAM24227-i1-1.1_002220 1175629.AJTG01000022_gene1757 4.46e-163 463.0 COG1957@1|root,COG1957@2|Bacteria,1TQUN@1239|Firmicutes,4HD26@91061|Bacilli 91061|Bacilli F Inosine-uridine nucleoside N-ribohydrolase - - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro gnl|extdb|FAM24227-i1-1.1_002214 1408438.JADD01000012_gene1656 1.95e-205 579.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HE6F@91061|Bacilli,27EF4@186827|Aerococcaceae 91061|Bacilli S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 gnl|extdb|FAM24227-i1-1.1_002218 1399115.U719_08260 0.000119 46.2 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli 91061|Bacilli M Sortase and related acyltransferases - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 gnl|extdb|FAM24227-i1-1.1_002224 1141106.CAIB01000145_gene1287 6.23e-77 238.0 2C1MG@1|root,31CZM@2|Bacteria,1V6SE@1239|Firmicutes,4HJIS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002225 1141106.CAIB01000145_gene1286 1.28e-56 192.0 2BHZU@1|root,32C4E@2|Bacteria,1V745@1239|Firmicutes,4HMDN@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002226 1141106.CAIB01000145_gene1285 3.49e-144 442.0 28JJU@1|root,2Z9CS@2|Bacteria,1TPJQ@1239|Firmicutes,4HCK9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002227 388919.SSA_1817 1.97e-244 717.0 COG1100@1|root,COG1100@2|Bacteria,1TR11@1239|Firmicutes,4HDF4@91061|Bacilli 91061|Bacilli L Z1 domain - - - - - - - - - - - - Z1 gnl|extdb|FAM24227-i1-1.1_002228 334413.FMG_P0144 1.13e-126 377.0 2DBEF@1|root,2Z8SA@2|Bacteria,1V1J3@1239|Firmicutes,24FU9@186801|Clostridia 186801|Clostridia S NgoFVII restriction endonuclease - - - - - - - - - - - - RE_NgoFVII gnl|extdb|FAM24227-i1-1.1_002229 1123315.AUIP01000008_gene729 1.91e-186 530.0 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,4HC1I@91061|Bacilli 91061|Bacilli H cytosine-specific methyltransferase nlaXM - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase gnl|extdb|FAM24227-i1-1.1_002230 1432847.V5URQ5_9VIRU 9.94e-150 433.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage 10239|Viruses S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002231 1336234.JAGN01000025_gene729 8.63e-15 68.6 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3 gnl|extdb|FAM24227-i1-1.1_002222 388919.SSA_1812 1.99e-155 452.0 COG0270@1|root,COG0270@2|Bacteria,1UED5@1239|Firmicutes,4IQ47@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase gnl|extdb|FAM24227-i1-1.1_002223 1141106.CAIB01000145_gene1288 4.73e-18 90.9 2EJD9@1|root,33D4A@2|Bacteria,1UJTP@1239|Firmicutes,4HRTU@91061|Bacilli 91061|Bacilli S NgoFVII restriction endonuclease - - - - - - - - - - - - RE_NgoFVII gnl|extdb|FAM24227-i1-1.1_002232 1175629.AJTG01000004_gene777 8.25e-88 269.0 COG1409@1|root,COG1409@2|Bacteria,1UZZS@1239|Firmicutes,4HA7Y@91061|Bacilli,27ES0@186827|Aerococcaceae 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos gnl|extdb|FAM24227-i1-1.1_002233 1123299.AUKZ01000025_gene1740 2.48e-77 239.0 COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,4HI8N@91061|Bacilli 91061|Bacilli K Transcriptional XK27_03105 - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR gnl|extdb|FAM24227-i1-1.1_002235 1235279.C772_01952 3.61e-77 233.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,26ETJ@186818|Planococcaceae 91061|Bacilli T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS gnl|extdb|FAM24227-i1-1.1_002236 1408438.JADD01000003_gene226 0.0 1152.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,27ED9@186827|Aerococcaceae 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase gnl|extdb|FAM24227-i1-1.1_002237 1121871.AUAT01000007_gene1614 1.18e-227 644.0 COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,4HCHB@91061|Bacilli,27DRR@186827|Aerococcaceae 91061|Bacilli G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 gnl|extdb|FAM24227-i1-1.1_002238 1336234.JAGN01000038_gene382 4.05e-102 310.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,27GFR@186828|Carnobacteriaceae 91061|Bacilli K helix_turn _helix lactose operon repressor malR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 gnl|extdb|FAM24227-i1-1.1_002239 883114.HMPREF9709_00763 3.81e-135 390.0 COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia,22IXK@1570339|Peptoniphilaceae 186801|Clostridia S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 gnl|extdb|FAM24227-i1-1.1_002240 626369.HMPREF0446_00165 4.13e-20 84.0 COG4545@1|root,COG4545@2|Bacteria,1TX5X@1239|Firmicutes,4HSQP@91061|Bacilli 91061|Bacilli O Glutaredoxin-related protein - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002241 883112.HMPREF9707_00358 1.26e-60 189.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,27E1N@186827|Aerococcaceae 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 gnl|extdb|FAM24227-i1-1.1_002242 1408438.JADD01000003_gene230 1.82e-72 219.0 COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,4HJ7X@91061|Bacilli,27DZ8@186827|Aerococcaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gloA - 4.4.1.5 ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 M00491 R02530 RC00004,RC00740 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.16,3.A.1.1.2 - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_002243 1336234.JAGN01000025_gene729 8.63e-15 68.6 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3 gnl|extdb|FAM24227-i1-1.1_002244 883103.HMPREF9703_01124 1.97e-77 242.0 COG2116@1|root,COG2116@2|Bacteria,1V164@1239|Firmicutes,4HCK8@91061|Bacilli,27G9B@186828|Carnobacteriaceae 91061|Bacilli P Formate/nitrite transporter - - - ko:K02598 - - - - ko00000,ko02000 1.A.16.3 - - Form_Nir_trans gnl|extdb|FAM24227-i1-1.1_002245 268407.PWYN_11055 9.7e-87 274.0 COG1680@1|root,COG1680@2|Bacteria,1V8KF@1239|Firmicutes,4HIEX@91061|Bacilli,26VFI@186822|Paenibacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase gnl|extdb|FAM24227-i1-1.1_002246 565653.EGBG_01911 3.2e-77 238.0 COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HAJ4@91061|Bacilli,4B26Q@81852|Enterococcaceae 91061|Bacilli S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 gnl|extdb|FAM24227-i1-1.1_002247 1266845.Q783_06235 7.01e-67 206.0 COG4876@1|root,COG4876@2|Bacteria,1V4YD@1239|Firmicutes,4HIK1@91061|Bacilli,27I0N@186828|Carnobacteriaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2188) ydaT - - - - - - - - - - - DUF2188 gnl|extdb|FAM24227-i1-1.1_002248 1121871.AUAT01000012_gene594 9.89e-115 341.0 COG3768@1|root,COG3768@2|Bacteria,1V39W@1239|Firmicutes,4HTFY@91061|Bacilli,27EAD@186827|Aerococcaceae 91061|Bacilli S Domain of unknown function (DUF697) - - - - - - - - - - - - DUF697 gnl|extdb|FAM24227-i1-1.1_002249 1235755.ANAM01000001_gene172 3.26e-126 367.0 COG1464@1|root,COG1464@2|Bacteria,1TRMB@1239|Firmicutes,4HF2D@91061|Bacilli,4GYHR@90964|Staphylococcaceae 91061|Bacilli P NLPA lipoprotein metQ3 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_002250 1121024.AUCD01000013_gene151 1.03e-118 344.0 COG2011@1|root,COG2011@2|Bacteria,1TSJS@1239|Firmicutes,4HDYE@91061|Bacilli,27FR9@186828|Carnobacteriaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component metI1 - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_002251 1121024.AUCD01000013_gene152 1.4e-108 320.0 COG1135@1|root,COG1135@2|Bacteria,1TT0A@1239|Firmicutes,4HDXU@91061|Bacilli,27FD5@186828|Carnobacteriaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN2 - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_002252 1408438.JADD01000024_gene1292 6.08e-114 345.0 COG0025@1|root,COG0025@2|Bacteria,1TVSQ@1239|Firmicutes,4HD3H@91061|Bacilli,27DRE@186827|Aerococcaceae 91061|Bacilli P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger gnl|extdb|FAM24227-i1-1.1_002253 416269.APL_1881 2.41e-180 513.0 COG0151@1|root,COG0151@2|Bacteria,1R9D4@1224|Proteobacteria,1SCM1@1236|Gammaproteobacteria,1Y7Y7@135625|Pasteurellales 135625|Pasteurellales F Phosphoribosylglycinamide synthetase of Bacteria UniRef RepID A6VP22_ACTSZ Z012_06890 - - - - - - - - - - - ATP-grasp_4 gnl|extdb|FAM24227-i1-1.1_002254 1408438.JADD01000024_gene1287 1.66e-128 370.0 COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,4HB4B@91061|Bacilli,27DDX@186827|Aerococcaceae 91061|Bacilli S Putative esterase XK27_05675 - - - - - - - - - - - Esterase gnl|extdb|FAM24227-i1-1.1_002255 1122147.AUEH01000042_gene750 3.56e-50 162.0 COG3304@1|root,COG3304@2|Bacteria,1VADH@1239|Firmicutes,4HKHX@91061|Bacilli,3F7HH@33958|Lactobacillaceae 91061|Bacilli S Inner membrane component domain - - - - - - - - - - - - YccF gnl|extdb|FAM24227-i1-1.1_002256 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002258 908337.HMPREF9257_0042 2.15e-116 338.0 COG0149@1|root,COG0149@2|Bacteria,1UZAR@1239|Firmicutes,4HBA2@91061|Bacilli,27DHV@186827|Aerococcaceae 91061|Bacilli G Triose-phosphate isomerase tpiA_2 - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM,ThiG gnl|extdb|FAM24227-i1-1.1_002259 908337.HMPREF9257_0043 3.7e-92 272.0 COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,4HHPU@91061|Bacilli,27DZ6@186827|Aerococcaceae 91061|Bacilli S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 gnl|extdb|FAM24227-i1-1.1_002261 945021.TEH_04290 6.91e-46 149.0 COG3414@1|root,COG3414@2|Bacteria,1VCNU@1239|Firmicutes,4HM3X@91061|Bacilli,4B331@81852|Enterococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB gnl|extdb|FAM24227-i1-1.1_002262 945021.TEH_04300 6.22e-237 662.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HA1Q@91061|Bacilli,4AZER@81852|Enterococcaceae 91061|Bacilli G PTS system sugar-specific permease component - - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT gnl|extdb|FAM24227-i1-1.1_002263 945021.TEH_04310 4.17e-34 125.0 2E35G@1|root,32Y5F@2|Bacteria,1VGNI@1239|Firmicutes,4HYTU@91061|Bacilli,4B0WI@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002264 945021.TEH_04320 7.06e-101 298.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,4B1BS@81852|Enterococcaceae 91061|Bacilli G Class II Aldolase and Adducin N-terminal domain - - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II gnl|extdb|FAM24227-i1-1.1_002265 1552123.EP57_02640 6.44e-37 137.0 COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,4HARD@91061|Bacilli 91061|Bacilli K Transcriptional araR - - ko:K02103 - - - - ko00000,ko03000 - - - GntR,Peripla_BP_1,Peripla_BP_3 gnl|extdb|FAM24227-i1-1.1_002267 1266845.Q783_10770 2.75e-108 318.0 COG1484@1|root,COG1484@2|Bacteria,1UYIT@1239|Firmicutes,4HC2H@91061|Bacilli,27HBR@186828|Carnobacteriaceae 91061|Bacilli L Bacterial dnaA protein - - - - - - - - - - - - IstB_IS21 gnl|extdb|FAM24227-i1-1.1_002268 1266845.Q783_06960 1.04e-124 372.0 COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,4HC33@91061|Bacilli,27HIR@186828|Carnobacteriaceae 91061|Bacilli L PFAM Integrase, catalytic core - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002257 945021.TEH_10010 4.72e-138 397.0 COG0191@1|root,COG0191@2|Bacteria,1TRQY@1239|Firmicutes,4HC8E@91061|Bacilli,4B6BZ@81852|Enterococcaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II gatY - 4.1.2.13,4.1.2.40 ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01069,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase gnl|extdb|FAM24227-i1-1.1_002260 1071073.KI530536_gene967 1.12e-35 128.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HIAB@91061|Bacilli,1ZHIF@1386|Bacillus 91061|Bacilli GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 gnl|extdb|FAM24227-i1-1.1_002269 1408438.JADD01000003_gene150 1.5e-130 370.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,27DT8@186827|Aerococcaceae 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 gnl|extdb|FAM24227-i1-1.1_002270 883113.HMPREF9708_00289 4.18e-249 707.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,27DGX@186827|Aerococcaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,PUD gnl|extdb|FAM24227-i1-1.1_002271 1123359.AUIQ01000014_gene745 3.45e-44 152.0 COG1926@1|root,COG1926@2|Bacteria,1V256@1239|Firmicutes,4HIFY@91061|Bacilli 91061|Bacilli S Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran gnl|extdb|FAM24227-i1-1.1_002273 592010.GCWU000182_000412 6.25e-287 800.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,27DIA@186827|Aerococcaceae 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS gnl|extdb|FAM24227-i1-1.1_002274 1229520.ADIAL_0722 1.53e-102 301.0 COG1584@1|root,COG1584@2|Bacteria,1TSYX@1239|Firmicutes,4HEDP@91061|Bacilli,27GNS@186828|Carnobacteriaceae 91061|Bacilli S GPR1/FUN34/yaaH family - - - ko:K07034 - - - - ko00000 - - - Grp1_Fun34_YaaH gnl|extdb|FAM24227-i1-1.1_002275 1121085.AUCI01000011_gene1693 2.65e-06 51.6 COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,4HDPM@91061|Bacilli,1ZR5K@1386|Bacillus 91061|Bacilli S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt gnl|extdb|FAM24227-i1-1.1_002277 866775.HMPREF9243_1871 6.96e-23 92.8 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli,27E5H@186827|Aerococcaceae 91061|Bacilli S Nitroreductase family XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase gnl|extdb|FAM24227-i1-1.1_002278 1175629.AJTG01000007_gene1216 8.88e-06 48.1 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli,27E5H@186827|Aerococcaceae 91061|Bacilli S Nitroreductase family XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase gnl|extdb|FAM24227-i1-1.1_002272 1174504.AJTN02000156_gene1111 2.18e-52 171.0 COG1853@1|root,COG1853@2|Bacteria,1V7DF@1239|Firmicutes,4IQIK@91061|Bacilli 91061|Bacilli S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct gnl|extdb|FAM24227-i1-1.1_002279 1121024.AUCD01000032_gene1905 4.09e-276 759.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,27FAK@186828|Carnobacteriaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N gnl|extdb|FAM24227-i1-1.1_002280 1408438.JADD01000002_gene268 4.58e-286 791.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,4HBTQ@91061|Bacilli,27DCV@186827|Aerococcaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N gnl|extdb|FAM24227-i1-1.1_002281 1408438.JADD01000002_gene269 4.18e-146 415.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,27DQ8@186827|Aerococcaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM gnl|extdb|FAM24227-i1-1.1_002282 1121871.AUAT01000002_gene1390 3.06e-220 615.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,27DQY@186827|Aerococcaceae 91061|Bacilli G Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK gnl|extdb|FAM24227-i1-1.1_002283 883112.HMPREF9707_01521 2.72e-176 498.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,27EGJ@186827|Aerococcaceae 91061|Bacilli G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N gnl|extdb|FAM24227-i1-1.1_002284 1408438.JADD01000002_gene272 1.07e-125 371.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,27DNF@186827|Aerococcaceae 91061|Bacilli K Putative sugar-binding domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind gnl|extdb|FAM24227-i1-1.1_002285 883112.HMPREF9707_01519 1.95e-123 353.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,27DPQ@186827|Aerococcaceae 91061|Bacilli OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease gnl|extdb|FAM24227-i1-1.1_002286 1121024.AUCD01000013_gene138 5.2e-158 462.0 COG1409@1|root,COG1409@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,27GYT@186828|Carnobacteriaceae 91061|Bacilli S Purple acid Phosphatase, N-terminal domain ppe1 - - - - - - - - - - - Metallophos,Pur_ac_phosph_N,SLH,fn3 gnl|extdb|FAM24227-i1-1.1_002288 1121024.AUCD01000009_gene2035 1.27e-87 268.0 COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HHQX@91061|Bacilli,27HEZ@186828|Carnobacteriaceae 91061|Bacilli E Histidinol phosphatase and related hydrolases of the PHP family hisK - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - - gnl|extdb|FAM24227-i1-1.1_002289 1151292.QEW_2841 1.25e-71 223.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,2496B@186801|Clostridia 186801|Clostridia F Hydrolase, nudix family - - - - - - - - - - - - NUDIX,Nudix_N gnl|extdb|FAM24227-i1-1.1_002291 883112.HMPREF9707_01530 2.32e-13 65.9 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,27E9E@186827|Aerococcaceae 91061|Bacilli U Preprotein translocase SecG subunit secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG gnl|extdb|FAM24227-i1-1.1_002292 908337.HMPREF9257_1657 1.09e-68 219.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,27E0H@186827|Aerococcaceae 91061|Bacilli S Alpha/beta hydrolase family est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 gnl|extdb|FAM24227-i1-1.1_002293 883110.HMPREF9260_00949 0.0 944.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,27DK9@186827|Aerococcaceae 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 gnl|extdb|FAM24227-i1-1.1_002294 592010.GCWU000182_000382 3.11e-78 235.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,27E0Q@186827|Aerococcaceae 91061|Bacilli O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB gnl|extdb|FAM24227-i1-1.1_002290 927691.AEMI01000013_gene736 1.5e-31 113.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli 91061|Bacilli K Transcriptional regulator czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 gnl|extdb|FAM24227-i1-1.1_002295 1408438.JADD01000015_gene780 3.65e-97 293.0 28H7K@1|root,2Z7JT@2|Bacteria,1UPH1@1239|Firmicutes,4HE88@91061|Bacilli 91061|Bacilli P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system - - - ko:K02526 - - - - ko00000,ko02000 2.A.10.1 - - KdgT gnl|extdb|FAM24227-i1-1.1_002297 1128398.Curi_c19030 5.55e-32 120.0 COG1309@1|root,COG1309@2|Bacteria,1V6GJ@1239|Firmicutes,24J0S@186801|Clostridia,269CC@186813|unclassified Clostridiales 186801|Clostridia K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N gnl|extdb|FAM24227-i1-1.1_002298 1321820.HMPREF1983_00441 1.62e-133 388.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,3WEZV@539002|Bacillales incertae sedis 91061|Bacilli L PFAM Integrase catalytic region - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002300 1395513.P343_17030 2.46e-40 157.0 COG4097@1|root,COG4097@2|Bacteria,1UM4G@1239|Firmicutes,4IUNU@91061|Bacilli 91061|Bacilli P FAD-binding domain - - - - - - - - - - - - FAD_binding_8,NAD_binding_1 gnl|extdb|FAM24227-i1-1.1_002301 138119.DSY1210 6.32e-225 644.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,261F5@186807|Peptococcaceae 186801|Clostridia V ABC-type multidrug transport system, ATPase and permease component - - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_002302 138119.DSY1262 1.11e-12 68.9 COG1846@1|root,COG1846@2|Bacteria,1VFN4@1239|Firmicutes,24J33@186801|Clostridia 186801|Clostridia K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_34 gnl|extdb|FAM24227-i1-1.1_002303 1408438.JADD01000024_gene1293 3.08e-54 180.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,27F2Z@186827|Aerococcaceae 91061|Bacilli P NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 gnl|extdb|FAM24227-i1-1.1_002304 1266845.Q783_09980 2.24e-29 111.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002306 592010.GCWU000182_000408 1.87e-142 419.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli,27DHG@186827|Aerococcaceae 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red gnl|extdb|FAM24227-i1-1.1_002307 883112.HMPREF9707_00383 1.12e-128 368.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,27DBX@186827|Aerococcaceae 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase gnl|extdb|FAM24227-i1-1.1_002308 883112.HMPREF9707_00382 4.86e-232 645.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,27EH9@186827|Aerococcaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT gnl|extdb|FAM24227-i1-1.1_002309 1408438.JADD01000018_gene647 3.65e-124 367.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,27DTT@186827|Aerococcaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC gnl|extdb|FAM24227-i1-1.1_002310 592010.GCWU000182_000446 1.2e-90 277.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,27E0W@186827|Aerococcaceae 91061|Bacilli J Belongs to the protein N5-glutamine methyltransferase family prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS gnl|extdb|FAM24227-i1-1.1_002311 1121871.AUAT01000014_gene385 1.31e-207 580.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,27DD6@186827|Aerococcaceae 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 gnl|extdb|FAM24227-i1-1.1_002312 908337.HMPREF9257_1370 2.45e-109 317.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,27DSA@186827|Aerococcaceae 91061|Bacilli F Thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK gnl|extdb|FAM24227-i1-1.1_002305 592010.GCWU000182_000407 9.21e-145 423.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,27DHY@186827|Aerococcaceae 91061|Bacilli I Hydroxymethylglutaryl-coenzyme A synthase N terminal mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N gnl|extdb|FAM24227-i1-1.1_002313 1449337.JQLL01000001_gene1092 3.29e-189 531.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,27FTA@186828|Carnobacteriaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus gnl|extdb|FAM24227-i1-1.1_002314 1123274.KB899418_gene2327 7.71e-22 95.9 COG2247@1|root,COG2247@2|Bacteria 2|Bacteria M cell wall organization - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CW_binding_2,Glucosaminidase gnl|extdb|FAM24227-i1-1.1_002315 883112.HMPREF9707_00500 1.51e-64 198.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,27DZJ@186827|Aerococcaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 gnl|extdb|FAM24227-i1-1.1_002316 1121871.AUAT01000001_gene768 1.39e-106 312.0 COG1174@1|root,COG1174@2|Bacteria,1TQ5C@1239|Firmicutes,4HAVM@91061|Bacilli,27DYV@186827|Aerococcaceae 91061|Bacilli E ABC transporter, permease protein opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33800 BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_002317 908337.HMPREF9257_1227 7.46e-115 340.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HARV@91061|Bacilli,27DUM@186827|Aerococcaceae 91061|Bacilli M ABC transporter, substrate-binding protein, QAT family opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12835 OpuAC gnl|extdb|FAM24227-i1-1.1_002318 1423806.JCM15457_1518 4e-93 278.0 COG1174@1|root,COG1174@2|Bacteria,1TSX8@1239|Firmicutes,4HC1D@91061|Bacilli,3F4EM@33958|Lactobacillaceae 91061|Bacilli E ABC transporter permease opuCB - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_002319 1121871.AUAT01000001_gene771 5.77e-179 511.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,27DFJ@186827|Aerococcaceae 91061|Bacilli E ABC transporter, ATP-binding protein opuCA - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12845,iYO844.BSU33730 ABC_tran,CBS gnl|extdb|FAM24227-i1-1.1_002321 1121871.AUAT01000001_gene773 4.61e-73 224.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,27DXT@186827|Aerococcaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM gnl|extdb|FAM24227-i1-1.1_002322 592010.GCWU000182_000079 7.71e-32 113.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,27E6W@186827|Aerococcaceae 91061|Bacilli S KH domain ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 gnl|extdb|FAM24227-i1-1.1_002323 883112.HMPREF9707_00496 6.32e-47 151.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,27E34@186827|Aerococcaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 gnl|extdb|FAM24227-i1-1.1_002320 592010.GCWU000182_000072 5.66e-127 366.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,27DQR@186827|Aerococcaceae 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT gnl|extdb|FAM24227-i1-1.1_002324 1449342.JQMR01000001_gene365 8.36e-200 567.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,27FC8@186828|Carnobacteriaceae 91061|Bacilli L Transposase isp - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_002325 1121105.ATXL01000016_gene1617 2.36e-218 603.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,4AZ62@81852|Enterococcaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family mntA - - ko:K19975,ko:K19976 ko02010,map02010 M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.15 - - ZnuA gnl|extdb|FAM24227-i1-1.1_002326 888064.HMPREF9088_0866 4.53e-182 509.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,4B67W@81852|Enterococcaceae 91061|Bacilli P ABC transporter permease mtsB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K19976 ko02010,map02010 M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.15 - - ABC-3 gnl|extdb|FAM24227-i1-1.1_002327 888064.HMPREF9088_0867 1.23e-170 476.0 COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli,4B00Y@81852|Enterococcaceae 91061|Bacilli P ABC transporter, ATP-binding protein mntB - 3.6.3.35 ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 M00243,M00244,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15 - - ABC_tran gnl|extdb|FAM24227-i1-1.1_002328 888064.HMPREF9088_0868 0.0 995.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,4AZ7U@81852|Enterococcaceae 91061|Bacilli U H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp gnl|extdb|FAM24227-i1-1.1_002329 1121105.ATXL01000016_gene1612 1.17e-95 279.0 COG0589@1|root,COG0589@2|Bacteria,1V8UY@1239|Firmicutes,4HK2J@91061|Bacilli,4B39N@81852|Enterococcaceae 91061|Bacilli T Universal stress protein family - - - - - - - - - - - - Usp gnl|extdb|FAM24227-i1-1.1_002330 1140002.I570_02950 7.75e-20 86.7 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,4B1EX@81852|Enterococcaceae 91061|Bacilli L Integrase core domain tra981A - - ko:K07497 - - - - ko00000 - - - HTH_21,rve gnl|extdb|FAM24227-i1-1.1_002331 1158614.I592_03974 1.86e-36 128.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,4B1EX@81852|Enterococcaceae 91061|Bacilli L Integrase core domain is18 - - - - - - - - - - - HTH_21,rve,rve_3 gnl|extdb|FAM24227-i1-1.1_002334 240302.BN982_01631 4.51e-105 319.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002335 1229520.ADIAL_0052 3.5e-40 145.0 2DCP1@1|root,2ZETC@2|Bacteria,1W36U@1239|Firmicutes,4HZUP@91061|Bacilli,27HRT@186828|Carnobacteriaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002336 1229520.ADIAL_0053 2.49e-147 421.0 COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,4IQFR@91061|Bacilli,27GAJ@186828|Carnobacteriaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran gnl|extdb|FAM24227-i1-1.1_002337 1229520.ADIAL_0054 2.08e-53 170.0 COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,4HKVW@91061|Bacilli,27GKT@186828|Carnobacteriaceae 91061|Bacilli K Bacterial regulatory proteins, gntR family - - - - - - - - - - - - GntR gnl|extdb|FAM24227-i1-1.1_002338 406124.ACPC01000020_gene3933 1.58e-06 47.8 2BGET@1|root,32ACM@2|Bacteria,1UCQV@1239|Firmicutes,4IP72@91061|Bacilli,1ZPH2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002339 1121024.AUCD01000081_gene1442 2.15e-49 165.0 COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,4HCFH@91061|Bacilli,27FZR@186828|Carnobacteriaceae 91061|Bacilli L IstB-like ATP binding N-terminal - - - - - - - - - - - - IstB_IS21,IstB_IS21_ATP gnl|extdb|FAM24227-i1-1.1_002340 655812.HMPREF0061_0336 1.17e-155 448.0 COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,4HB6H@91061|Bacilli 91061|Bacilli L Integrase core domain - - - - - - - - - - - - HTH_23,rve gnl|extdb|FAM24227-i1-1.1_002341 1118057.CAGX01000073_gene180 6.18e-80 247.0 COG1484@1|root,COG1484@2|Bacteria,1TRWF@1239|Firmicutes,24FIP@186801|Clostridia,22IC3@1570339|Peptoniphilaceae 186801|Clostridia L Bacterial dnaA protein - - - - - - - - - - - - IstB_IS21 gnl|extdb|FAM24227-i1-1.1_002342 1121024.AUCD01000097_gene1448 8.69e-57 185.0 COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,4HCFH@91061|Bacilli,27FZR@186828|Carnobacteriaceae 91061|Bacilli L IstB-like ATP binding N-terminal - - - - - - - - - - - - IstB_IS21,IstB_IS21_ATP gnl|extdb|FAM24227-i1-1.1_002343 1121024.AUCD01000097_gene1449 4.23e-217 617.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli,27FJI@186828|Carnobacteriaceae 91061|Bacilli L Integrase core domain - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002346 883110.HMPREF9260_00622 3.12e-198 555.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,27DCD@186827|Aerococcaceae 91061|Bacilli EP Oligopeptide/dipeptide transporter, C-terminal region oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_002347 883110.HMPREF9260_00623 7.48e-153 437.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,27DP1@186827|Aerococcaceae 91061|Bacilli EP N-terminal TM domain of oligopeptide transport permease C oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N gnl|extdb|FAM24227-i1-1.1_002348 883110.HMPREF9260_00624 3.37e-167 473.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,27DPA@186827|Aerococcaceae 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component oppB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_002349 1408438.JADD01000014_gene576 3.73e-132 391.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27DIN@186827|Aerococcaceae 91061|Bacilli E Receptor family ligand-binding protein livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 gnl|extdb|FAM24227-i1-1.1_002350 1122129.AUEF01000014_gene1370 2.82e-121 358.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,4GXJ0@90964|Staphylococcaceae 91061|Bacilli E COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 gnl|extdb|FAM24227-i1-1.1_002345 883110.HMPREF9260_00621 1.16e-155 444.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,27DHS@186827|Aerococcaceae 91061|Bacilli E Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_002353 883112.HMPREF9707_01023 1.48e-71 220.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,27DYZ@186827|Aerococcaceae 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam gnl|extdb|FAM24227-i1-1.1_002354 1408438.JADD01000006_gene978 3.07e-19 83.6 2EMDH@1|root,33F2E@2|Bacteria,1TX6C@1239|Firmicutes,4I62W@91061|Bacilli,27EVA@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002355 1122143.AUEG01000014_gene1941 0.0 1337.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,27FS5@186828|Carnobacteriaceae 91061|Bacilli F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN gnl|extdb|FAM24227-i1-1.1_002356 945021.TEH_12510 9.77e-81 246.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4HH26@91061|Bacilli,4B2AB@81852|Enterococcaceae 91061|Bacilli S Cobalamin adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans gnl|extdb|FAM24227-i1-1.1_002357 626369.HMPREF0446_01375 7.66e-52 171.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli,27GCZ@186828|Carnobacteriaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - ECF_trnsprt gnl|extdb|FAM24227-i1-1.1_002358 883112.HMPREF9707_00284 5.71e-34 122.0 2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 gnl|extdb|FAM24227-i1-1.1_002352 1175629.AJTG01000028_gene178 4.86e-99 291.0 COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli,27DXJ@186827|Aerococcaceae 91061|Bacilli L Uracil DNA glycosylase superfamily ung2 - - - - - - - - - - - UDG gnl|extdb|FAM24227-i1-1.1_002359 1384057.CD33_18220 9.9e-21 98.2 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,3IXRC@400634|Lysinibacillus 91061|Bacilli S nuclease - - - - - - - - - - - - NERD gnl|extdb|FAM24227-i1-1.1_002360 883112.HMPREF9707_00019 4.72e-120 352.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,27DV6@186827|Aerococcaceae 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N gnl|extdb|FAM24227-i1-1.1_002361 883112.HMPREF9707_00020 2.69e-89 279.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,27DV2@186827|Aerococcaceae 91061|Bacilli S YbbR-like protein ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR gnl|extdb|FAM24227-i1-1.1_002362 592010.GCWU000182_000627 5.11e-258 715.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,27DKP@186827|Aerococcaceae 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV gnl|extdb|FAM24227-i1-1.1_002363 1408438.JADD01000029_gene1358 3.31e-75 239.0 COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,4HGQ9@91061|Bacilli,27E1J@186827|Aerococcaceae 91061|Bacilli Q Methyltransferase domain rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 gnl|extdb|FAM24227-i1-1.1_002364 1408438.JADD01000013_gene1752 4.86e-13 63.5 COG2826@1|root,COG2826@2|Bacteria 2|Bacteria L transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002365 1121024.AUCD01000037_gene427 1.17e-208 588.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,27FUI@186828|Carnobacteriaceae 91061|Bacilli S HI0933-like protein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like gnl|extdb|FAM24227-i1-1.1_002366 1175629.AJTG01000031_gene1429 1.78e-71 221.0 2A1RE@1|root,30PZZ@2|Bacteria,1V46H@1239|Firmicutes,4IR0Y@91061|Bacilli,27DZE@186827|Aerococcaceae 91061|Bacilli - - - - - ko:K16788 - - - - ko00000,ko02000 2.A.88.5 - - - gnl|extdb|FAM24227-i1-1.1_002369 1175629.AJTG01000031_gene1428 3.19e-62 197.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,27E2U@186827|Aerococcaceae 91061|Bacilli S 3H domain yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 gnl|extdb|FAM24227-i1-1.1_002370 883110.HMPREF9260_01689 2.73e-86 255.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,27DV3@186827|Aerococcaceae 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 gnl|extdb|FAM24227-i1-1.1_002371 1408438.JADD01000012_gene1683 3e-75 226.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,27DZ7@186827|Aerococcaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 gnl|extdb|FAM24227-i1-1.1_002372 1340434.AXVA01000007_gene5195 2.57e-07 59.7 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD gnl|extdb|FAM24227-i1-1.1_002373 1229520.ADIAL_1934 4.86e-114 338.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,27FHA@186828|Carnobacteriaceae 91061|Bacilli G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB gnl|extdb|FAM24227-i1-1.1_002375 1123359.AUIQ01000011_gene1020 4.56e-29 121.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD gnl|extdb|FAM24227-i1-1.1_002376 883112.HMPREF9707_01112 7.01e-54 181.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,27E5Y@186827|Aerococcaceae 91061|Bacilli O Universal bacterial protein YeaZ yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 gnl|extdb|FAM24227-i1-1.1_002377 883112.HMPREF9707_01113 1.36e-52 173.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,27E79@186827|Aerococcaceae 91061|Bacilli K Acetyltransferase (GNAT) domain rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 gnl|extdb|FAM24227-i1-1.1_002378 883112.HMPREF9707_01114 2.72e-21 90.5 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 gnl|extdb|FAM24227-i1-1.1_002379 1408438.JADD01000005_gene1205 6.63e-167 475.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,27DHB@186827|Aerococcaceae 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 gnl|extdb|FAM24227-i1-1.1_002374 592010.GCWU000182_000661 7.24e-56 181.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,27EPB@186827|Aerococcaceae 91061|Bacilli I Thioesterase superfamily ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 - - - - ko00000,ko01000 - - - 4HBT gnl|extdb|FAM24227-i1-1.1_002380 169963.lmo2189 1.49e-08 64.3 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,26K8B@186820|Listeriaceae 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA gnl|extdb|FAM24227-i1-1.1_002381 883112.HMPREF9707_01418 0.0 882.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,27DM5@186827|Aerococcaceae 91061|Bacilli E Oligopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N gnl|extdb|FAM24227-i1-1.1_002385 1175629.AJTG01000031_gene1403 1.2e-117 338.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HKAA@91061|Bacilli,27EXD@186827|Aerococcaceae 91061|Bacilli E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI gnl|extdb|FAM24227-i1-1.1_002387 1175629.AJTG01000031_gene1401 4.67e-161 453.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,27EH2@186827|Aerococcaceae 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA gnl|extdb|FAM24227-i1-1.1_002389 1131730.BAVI_00265 6.24e-40 142.0 28PQ5@1|root,2ZCCA@2|Bacteria,1V1RW@1239|Firmicutes,4HGAM@91061|Bacilli,1ZFQB@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2812) - - - - - - - - - - - - DUF2812 gnl|extdb|FAM24227-i1-1.1_002390 565653.EGBG_00735 1.52e-32 119.0 2CKMR@1|root,32VKF@2|Bacteria,1VAAV@1239|Firmicutes,4HXBV@91061|Bacilli,4B6PJ@81852|Enterococcaceae 91061|Bacilli S Putative zincin peptidase - - - - - - - - - - - - DUF3267 gnl|extdb|FAM24227-i1-1.1_002391 655812.HMPREF0061_0178 4.69e-86 253.0 COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,4HJ7X@91061|Bacilli,27DZ8@186827|Aerococcaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gloA - 4.4.1.5 ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 M00491 R02530 RC00004,RC00740 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.16,3.A.1.1.2 - - Glyoxalase gnl|extdb|FAM24227-i1-1.1_002388 1121085.AUCI01000007_gene1151 1.19e-32 116.0 COG1695@1|root,COG1695@2|Bacteria,1VANP@1239|Firmicutes,4HKRZ@91061|Bacilli,1ZIEN@1386|Bacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR gnl|extdb|FAM24227-i1-1.1_002394 1235755.ANAM01000003_gene856 7.22e-34 134.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,4H0B4@90964|Staphylococcaceae 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD gnl|extdb|FAM24227-i1-1.1_002395 1408438.JADD01000005_gene1206 6.53e-315 876.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,27DCE@186827|Aerococcaceae 91061|Bacilli S ABC transporter, ATP-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn gnl|extdb|FAM24227-i1-1.1_002396 1121871.AUAT01000001_gene854 1.38e-36 135.0 29PFW@1|root,30AE1@2|Bacteria,1U6IP@1239|Firmicutes,4IGB2@91061|Bacilli,27EWT@186827|Aerococcaceae 91061|Bacilli - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002397 1121871.AUAT01000001_gene792 1.82e-32 114.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,27E5N@186827|Aerococcaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding gnl|extdb|FAM24227-i1-1.1_002398 883112.HMPREF9707_00484 9.38e-201 560.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,27DJN@186827|Aerococcaceae 91061|Bacilli P Oligopeptide/dipeptide transporter, C-terminal region oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_002399 883112.HMPREF9707_00485 1.05e-193 541.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,27DPU@186827|Aerococcaceae 91061|Bacilli E Oligopeptide/dipeptide transporter, C-terminal region oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY gnl|extdb|FAM24227-i1-1.1_002400 908337.HMPREF9257_1247 2.59e-183 515.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,27DI9@186827|Aerococcaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component oppB - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 gnl|extdb|FAM24227-i1-1.1_002401 883112.HMPREF9707_00487 2.52e-155 444.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HA7I@91061|Bacilli,27DCW@186827|Aerococcaceae 91061|Bacilli EP N-terminal TM domain of oligopeptide transport permease C oppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N gnl|extdb|FAM24227-i1-1.1_002402 1336234.JAGN01000025_gene729 8.63e-15 68.6 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3 gnl|extdb|FAM24227-i1-1.1_002404 411483.FAEPRAA2165_03263 1.08e-69 240.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,248P6@186801|Clostridia 186801|Clostridia V abc transporter atp-binding protein - - - - - - - - - - - - ABC_membrane,ABC_tran gnl|extdb|FAM24227-i1-1.1_002405 1284708.HMPREF1634_03685 9.96e-84 290.0 COG0515@1|root,COG0515@2|Bacteria,1TSH3@1239|Firmicutes,24KVJ@186801|Clostridia 186801|Clostridia KLT Lanthionine synthetase C-like protein - - - - - - - - - - - - LANC_like,Pkinase gnl|extdb|FAM24227-i1-1.1_002406 883113.HMPREF9708_01421 5.58e-48 162.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,27ES1@186827|Aerococcaceae 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002411 293826.Amet_1406 3.41e-36 139.0 2E32G@1|root,32Y2Q@2|Bacteria,1VH34@1239|Firmicutes,24X2A@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002412 395495.Lcho_1314 6.83e-61 202.0 28KAG@1|root,2Z9XS@2|Bacteria,1QUUC@1224|Proteobacteria,2VX9E@28216|Betaproteobacteria 28216|Betaproteobacteria S Abortive infection C-terminus - - - - - - - - - - - - Abi_C gnl|extdb|FAM24227-i1-1.1_002413 428125.CLOLEP_02314 2.03e-67 226.0 2DBQ2@1|root,2ZABR@2|Bacteria,1TR5Z@1239|Firmicutes,24U5A@186801|Clostridia,3WKZ9@541000|Ruminococcaceae 186801|Clostridia S COG NOG15996 non supervised orthologous group - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002414 1288.SXYLSMQ121_1026 0.000164 49.3 COG1357@1|root,COG1357@2|Bacteria,1VAPB@1239|Firmicutes,4HH43@91061|Bacilli,4GZBF@90964|Staphylococcaceae 91061|Bacilli S Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide,Pentapeptide_4 gnl|extdb|FAM24227-i1-1.1_002415 658086.HMPREF0994_04127 2.57e-38 134.0 COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,27NWY@186928|unclassified Lachnospiraceae 186801|Clostridia K Acetyltransferase (GNAT) domain - - - ko:K03826 - - - - ko00000,ko01000 - - - Acetyltransf_10,Acetyltransf_7 gnl|extdb|FAM24227-i1-1.1_002416 1179226.AJXO01000075_gene2895 3.43e-15 77.4 COG2963@1|root,COG2963@2|Bacteria,1V2T5@1239|Firmicutes,4HFZ1@91061|Bacilli,4H1B5@90964|Staphylococcaceae 91061|Bacilli L Transposase - - - - - - - - - - - - HTH_28,HTH_Tnp_1 gnl|extdb|FAM24227-i1-1.1_002418 106648.BBLJ01000085_gene4448 4.15e-186 519.0 COG1708@1|root,COG1708@2|Bacteria,1QVMI@1224|Proteobacteria,1RU4E@1236|Gammaproteobacteria,3NSZE@468|Moraxellaceae 1236|Gammaproteobacteria H Domain of unknown function (DUF4111) - - 2.7.7.47 ko:K00984 - - - - ko00000,ko01000,ko01504 - - - DUF4111,NTP_transf_2 gnl|extdb|FAM24227-i1-1.1_002419 1035184.HMPREF1042_0699 2.22e-107 318.0 2DKY4@1|root,30URY@2|Bacteria,1V2IU@1239|Firmicutes,4ITR4@91061|Bacilli,42E1J@671232|Streptococcus anginosus group 91061|Bacilli S Domain of unknown function (DUF4037) - - - - - - - - - - - - DUF4037,NTP_transf_2 gnl|extdb|FAM24227-i1-1.1_002427 1449335.JQLG01000004_gene1164 3.78e-10 62.8 COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,4HAJS@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 gnl|extdb|FAM24227-i1-1.1_002428 226185.EF_0782 1.84e-82 268.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,4B042@81852|Enterococcaceae 91061|Bacilli K Sigma-54 factor, Activator interacting domain (AID) rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD gnl|extdb|FAM24227-i1-1.1_002429 1449337.JQLL01000001_gene1016 1.8e-13 65.5 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002430 1408438.JADD01000029_gene1373 4.26e-57 186.0 COG0204@1|root,COG0204@2|Bacteria,1V5X9@1239|Firmicutes,4HHBW@91061|Bacilli 91061|Bacilli I Acyl-transferase - - - - - - - - - - - - - gnl|extdb|FAM24227-i1-1.1_002431 1408438.JADD01000029_gene1374 1.47e-66 212.0 COG1215@1|root,COG1215@2|Bacteria,1UIAX@1239|Firmicutes,4ITN6@91061|Bacilli 91061|Bacilli M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 gnl|extdb|FAM24227-i1-1.1_002433 1121105.ATXL01000038_gene534 1.5e-21 87.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli,4B3J9@81852|Enterococcaceae 91061|Bacilli L Integrase core domain - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002434 883112.HMPREF9707_00489 1.93e-294 819.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,27EAG@186827|Aerococcaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle oppA1 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 gnl|extdb|FAM24227-i1-1.1_002435 1449337.JQLL01000001_gene1016 6.92e-13 63.9 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002436 1266845.Q783_11760 1.06e-62 207.0 COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,4HC33@91061|Bacilli,27HIR@186828|Carnobacteriaceae 91061|Bacilli L PFAM Integrase, catalytic core - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002437 565653.EGBG_02255 9.15e-120 347.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,4AZK0@81852|Enterococcaceae 91061|Bacilli G Class II Aldolase and Adducin N-terminal domain araD - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II gnl|extdb|FAM24227-i1-1.1_002438 1122128.AUEE01000008_gene1803 8.09e-44 161.0 COG4585@1|root,COG4585@2|Bacteria,1UUZ9@1239|Firmicutes,4HJHM@91061|Bacilli,4H0KZ@90964|Staphylococcaceae 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c_5,HisKA_3 gnl|extdb|FAM24227-i1-1.1_002440 1121105.ATXL01000017_gene1609 3.91e-38 133.0 COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,4HCFH@91061|Bacilli 91061|Bacilli L COG1484 DNA replication protein - - - - - - - - - - - - IstB_IS21,IstB_IS21_ATP gnl|extdb|FAM24227-i1-1.1_002441 1229520.ADIAL_0004 0.0 983.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli,27FJI@186828|Carnobacteriaceae 91061|Bacilli L Integrase core domain - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002442 883081.HMPREF9698_00897 1.67e-264 729.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,27FQC@186828|Carnobacteriaceae 91061|Bacilli L Reverse transcriptase (RNA-dependent DNA polymerase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 gnl|extdb|FAM24227-i1-1.1_002443 1336234.JAGN01000025_gene729 8.63e-15 68.6 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3 gnl|extdb|FAM24227-i1-1.1_002458 1121024.AUCD01000067_gene695 4.03e-232 647.0 COG3385@1|root,COG3385@2|Bacteria,1TPH7@1239|Firmicutes,4HB3I@91061|Bacilli,27H8U@186828|Carnobacteriaceae 91061|Bacilli L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 gnl|extdb|FAM24227-i1-1.1_002459 1121024.AUCD01000067_gene695 1.44e-255 706.0 COG3385@1|root,COG3385@2|Bacteria,1TPH7@1239|Firmicutes,4HB3I@91061|Bacilli,27H8U@186828|Carnobacteriaceae 91061|Bacilli L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 gnl|extdb|FAM24227-i1-1.1_002460 1229520.ADIAL_0469 1.24e-148 437.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,27FC8@186828|Carnobacteriaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_002461 698758.AXY_03720 5.87e-11 57.4 COG2826@1|root,COG2826@2|Bacteria 2|Bacteria L transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002462 1423816.BACQ01000062_gene2396 1.04e-82 251.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase kdgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase gnl|extdb|FAM24227-i1-1.1_002463 1158601.I585_01335 1.35e-31 117.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system - - 2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279 R03232,R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5.1 - - HTH_11,Mga,PEP-utilisers_N,PEP-utilizers,PRD,PTS-HPr,PTS_EIIA_2,PTS_IIB gnl|extdb|FAM24227-i1-1.1_002464 1121864.OMO_02298 2.63e-221 617.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,4B0EH@81852|Enterococcaceae 91061|Bacilli L to GB X15145, SP P26998, PID 1340164, GB X15145, SP P26998, and PID 1340164 B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut gnl|extdb|FAM24227-i1-1.1_002465 1449342.JQMR01000001_gene643 2.1e-123 370.0 COG3547@1|root,COG3547@2|Bacteria,1URDM@1239|Firmicutes,4I4Q1@91061|Bacilli,27HJH@186828|Carnobacteriaceae 91061|Bacilli L Transposase (IS116 IS110 IS902 family) - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 gnl|extdb|FAM24227-i1-1.1_002466 1035187.HMPREF9959_1922 1.24e-138 409.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,2TP04@28037|Streptococcus mitis 91061|Bacilli L zinc-finger of transposase IS204/IS1001/IS1096/IS1165 - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 gnl|extdb|FAM24227-i1-1.1_002467 883112.HMPREF9707_00598 1e-136 399.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,27EPK@186827|Aerococcaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002469 1408438.JADD01000013_gene1752 4.86e-13 63.5 COG2826@1|root,COG2826@2|Bacteria 2|Bacteria L transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002470 558169.AGAV01000005_gene2565 3.65e-92 278.0 COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,4HCFH@91061|Bacilli 91061|Bacilli L COG1484 DNA replication protein - - - - - - - - - - - - IstB_IS21,IstB_IS21_ATP gnl|extdb|FAM24227-i1-1.1_002471 398511.BpOF4_03680 2.43e-21 93.6 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli,1ZHE4@1386|Bacillus 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002472 1410626.JHXB01000005_gene1345 6.92e-104 314.0 COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,24B89@186801|Clostridia,27Q3Y@186928|unclassified Lachnospiraceae 186801|Clostridia L HTH-like domain - - - - - - - - - - - - HTH_21,rve,rve_2 gnl|extdb|FAM24227-i1-1.1_002473 1140001.I571_00552 2.43e-189 526.0 COG2801@1|root,COG2801@2|Bacteria,1TPEH@1239|Firmicutes,4HCHG@91061|Bacilli,4B04U@81852|Enterococcaceae 91061|Bacilli L Integrase core domain - - - - - - - - - - - - HTH_21,rve,rve_3 gnl|extdb|FAM24227-i1-1.1_002474 655812.HMPREF0061_1917 1.3e-168 474.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli,27F00@186827|Aerococcaceae 91061|Bacilli L Integrase core domain - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002476 1140001.I571_01927 1.05e-150 429.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli,4B15P@81852|Enterococcaceae 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002477 1266845.Q783_09980 2.24e-29 111.0 COG2826@1|root,COG2826@2|Bacteria,1TWVR@1239|Firmicutes,4HCM1@91061|Bacilli 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002478 416870.llmg_0703 2.47e-32 125.0 COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,4HG6W@91061|Bacilli 91061|Bacilli L FOG Transposase and inactivated - - - - - - - - - - - - DDE_Tnp_1 gnl|extdb|FAM24227-i1-1.1_002479 398511.BpOF4_03680 2.81e-77 246.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli,1ZHE4@1386|Bacillus 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002483 1449335.JQLG01000004_gene247 4.24e-36 135.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli,27FJI@186828|Carnobacteriaceae 91061|Bacilli L Integrase core domain - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002484 1122128.AUEE01000016_gene2069 2.17e-43 155.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli,4H0PN@90964|Staphylococcaceae 91061|Bacilli L Integrase core domain - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002485 398511.BpOF4_03680 9.95e-22 94.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli,1ZHE4@1386|Bacillus 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002486 558169.AGAV01000005_gene2566 2.09e-15 76.3 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002488 1175629.AJTG01000031_gene1414 3.04e-41 142.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,27ES1@186827|Aerococcaceae 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002489 1121105.ATXL01000017_gene1609 2.82e-19 85.1 COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,4HCFH@91061|Bacilli 91061|Bacilli L COG1484 DNA replication protein - - - - - - - - - - - - IstB_IS21,IstB_IS21_ATP gnl|extdb|FAM24227-i1-1.1_002490 1121105.ATXL01000038_gene534 1.5e-21 87.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli,4B3J9@81852|Enterococcaceae 91061|Bacilli L Integrase core domain - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve gnl|extdb|FAM24227-i1-1.1_002491 1123284.KB899066_gene1456 7.28e-32 122.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,4HA39@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - rve gnl|extdb|FAM24227-i1-1.1_002492 1123359.AUIQ01000005_gene1345 2.93e-27 108.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,4B0HK@81852|Enterococcaceae 91061|Bacilli L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut gnl|extdb|FAM24227-i1-1.1_002493 883081.HMPREF9698_00474 1.84e-27 108.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,27FPR@186828|Carnobacteriaceae 91061|Bacilli L L COG3328 Transposase and inactivated derivatives - - - - - - - - - - - - Transposase_mut gnl|extdb|FAM24227-i1-1.1_002494 883081.HMPREF9698_00474 1.32e-27 109.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,27FPR@186828|Carnobacteriaceae 91061|Bacilli L L COG3328 Transposase and inactivated derivatives - - - - - - - - - - - - Transposase_mut ## 2224 queries scanned ## Total time (seconds): 4.618920564651489 ## Rate: 481.50 q/s