# emapper version: emapper-1.0.3-35-g63c274b emapper DB: 2.0 # command: ./emapper.py --cpu 6 -i /data/shared/emapper_jobs/user_data/MM__t8l94e6/query_seqs.fa --output query_seqs.fa --output_dir /data/shared/emapper_jobs/user_data/MM__t8l94e6 -m diamond -d none --tax_scope auto --go_evidence non-electronic --target_orthologs all --seed_ortholog_evalue 0.001 --seed_ortholog_score 60 --query-cover 20 --subject-cover 0 --override --temp_dir /data/shared/emapper_jobs/user_data/MM__t8l94e6 # time: Sat May 30 11:20:01 2020 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction gnl|extdb|FAM19036-p1-1.1_000001 1171373.PACID_32510 2.5e-220 771.2 Propionibacteriales ybdL GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.6.1.17,2.6.1.88 ko:K14267,ko:K14287 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475,R08618 RC00006,RC00025 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv0858c Bacteria 2GJ7R@201174,4DN5T@85009,COG0436@1,COG0436@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme gnl|extdb|FAM19036-p1-1.1_000003 1122997.AUDD01000022_gene2166 5.7e-48 196.8 Actinobacteria Bacteria 2EJ20@1,2GR1E@201174,33CT5@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000004 1122998.AUHZ01000014_gene482 8e-143 513.5 Propionibacteriales Bacteria 2GJJX@201174,4DNS3@85009,COG0787@1,COG0787@2 NA|NA|NA M Alanine racemase, N-terminal domain gnl|extdb|FAM19036-p1-1.1_000011 1171373.PACID_32420 4e-142 510.8 Propionibacteriales nfo GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJJQ@201174,4DN5G@85009,COG0648@1,COG0648@2 NA|NA|NA L Xylose isomerase-like TIM barrel gnl|extdb|FAM19036-p1-1.1_000013 1171373.PACID_32400 0.0 1248.4 Actinobacteria PPA2234 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,COG1022@1,COG1022@2 NA|NA|NA I AMP-dependent synthetase and ligase gnl|extdb|FAM19036-p1-1.1_000014 1171373.PACID_32390 2.1e-69 268.1 Actinobacteria 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 R07459,R07461 RC00043 ko00000,ko00001,ko01000 Bacteria 2IH0R@201174,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain gnl|extdb|FAM19036-p1-1.1_000015 1171373.PACID_32380 2.7e-150 538.1 Propionibacteriales ko:K07243 ko00000,ko02000 2.A.108.1,2.A.108.2 Bacteria 2GJ22@201174,4DPYF@85009,COG0672@1,COG0672@2 NA|NA|NA P Iron permease FTR1 family gnl|extdb|FAM19036-p1-1.1_000016 1171373.PACID_32370 6e-212 743.4 Propionibacteriales ycdO GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511 ko:K07224 ko00000,ko02000 2.A.108.2.3 Bacteria 2GJPY@201174,4DNVH@85009,COG2822@1,COG2822@2 NA|NA|NA P Imelysin gnl|extdb|FAM19036-p1-1.1_000017 1171373.PACID_32360 4e-251 873.6 Propionibacteriales efeN ko:K16301 ko00000,ko01000,ko02000 2.A.108.2.3 Bacteria 2GIUB@201174,4DNFJ@85009,COG2837@1,COG2837@2 NA|NA|NA P Dyp-type peroxidase family gnl|extdb|FAM19036-p1-1.1_000018 1171373.PACID_32350 1.1e-46 192.2 Propionibacteriales rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IQHD@201174,4DRPR@85009,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA gnl|extdb|FAM19036-p1-1.1_000019 1171373.PACID_32340 3.6e-66 258.1 Propionibacteriales ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GMM3@201174,4DQ95@85009,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein gnl|extdb|FAM19036-p1-1.1_000020 1171373.PACID_32330 4e-34 150.2 Propionibacteriales rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 2IQ92@201174,4DRVS@85009,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit gnl|extdb|FAM19036-p1-1.1_000021 1171373.PACID_32320 1.1e-74 285.8 Propionibacteriales rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKX7@201174,4DQYG@85009,COG0359@1,COG0359@2 NA|NA|NA J binds to the 23S rRNA gnl|extdb|FAM19036-p1-1.1_000022 33876.JNXY01000016_gene7082 1.1e-08 67.0 Micromonosporales Bacteria 2IKMG@201174,4DDSK@85008,COG1514@1,COG1514@2 NA|NA|NA J 2'-5' RNA ligase superfamily gnl|extdb|FAM19036-p1-1.1_000023 1171373.PACID_32290 6.4e-146 523.5 Propionibacteriales uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJVG@201174,4DQ00@85009,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin gnl|extdb|FAM19036-p1-1.1_000024 1171373.PACID_32280 1.6e-124 452.2 Actinobacteria viuB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0015688,GO:0015891,GO:0016020,GO:0016491,GO:0016722,GO:0016723,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033212,GO:0033554,GO:0042592,GO:0042594,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0051716,GO:0052851,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0098771,GO:1901678 Bacteria 2GN5R@201174,COG2375@1,COG2375@2 NA|NA|NA P siderophore-interacting protein gnl|extdb|FAM19036-p1-1.1_000025 1171373.PACID_32260 4.2e-203 713.8 Propionibacteriales namA 1.6.99.1 ko:K00354 R00282 RC00001 ko00000,ko01000 Bacteria 2GK8E@201174,4DP05@85009,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family gnl|extdb|FAM19036-p1-1.1_000026 1171373.PACID_32250 1.1e-65 255.8 Propionibacteriales Bacteria 2IMHW@201174,4DVIM@85009,COG3011@1,COG3011@2 NA|NA|NA S Protein of unknown function, DUF393 gnl|extdb|FAM19036-p1-1.1_000027 1171373.PACID_32240 2.6e-45 187.6 Propionibacteriales ko:K09780 ko00000 Bacteria 2HZH9@201174,4DST8@85009,COG2350@1,COG2350@2 NA|NA|NA S YCII-related domain gnl|extdb|FAM19036-p1-1.1_000028 1171373.PACID_32230 1.3e-162 578.9 Propionibacteriales czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 2GMRZ@201174,4DNBF@85009,COG1230@1,COG1230@2 NA|NA|NA P Cation efflux family gnl|extdb|FAM19036-p1-1.1_000029 1171373.PACID_32220 1.1e-201 709.1 Propionibacteriales cvpA Bacteria 2GJ92@201174,4DPBR@85009,COG0265@1,COG0265@2 NA|NA|NA O Colicin V production protein gnl|extdb|FAM19036-p1-1.1_000031 1171373.PACID_32200 3.2e-235 820.8 Propionibacteriales yibF Bacteria 2GKJ4@201174,4DQ4D@85009,COG5438@1,COG5438@2 NA|NA|NA S YibE/F-like protein gnl|extdb|FAM19036-p1-1.1_000033 1171373.PACID_32180 1e-125 456.1 Propionibacteriales Bacteria 2GIZB@201174,4DP6U@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM19036-p1-1.1_000034 1171373.PACID_32170 4.5e-165 587.8 Propionibacteriales 3.4.13.21,3.4.15.6 ko:K05995,ko:K13282 R09722 RC00064,RC00141 ko00000,ko01000,ko01002 Bacteria 2IG1C@201174,4DSB5@85009,COG4242@1,COG4242@2 NA|NA|NA PQ Belongs to the peptidase S51 family gnl|extdb|FAM19036-p1-1.1_000035 1171373.PACID_32160 4.2e-170 604.0 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJV7@201174,4DPZH@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_000036 1171373.PACID_32150 8.3e-249 865.9 Propionibacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2IGP4@201174,4DTPH@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_000037 1171373.PACID_32140 4.6e-177 627.1 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GKBJ@201174,4DU5P@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000040 1171373.PACID_32110 0.0 1401.7 Propionibacteriales ko:K09955 ko00000 Bacteria 2GM60@201174,4DT57@85009,COG3533@1,COG3533@2 NA|NA|NA P Beta-L-arabinofuranosidase, GH127 gnl|extdb|FAM19036-p1-1.1_000041 1171373.PACID_32100 0.0 1337.4 Actinobacteria rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 2GJJ1@201174,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase gnl|extdb|FAM19036-p1-1.1_000042 1171373.PACID_32090 2.1e-163 581.6 Propionibacteriales ocd GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.5.1.1,1.5.1.49,4.3.1.12 ko:K01750,ko:K19742,ko:K19743 ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230 R00671,R01246,R01249,R02201,R02203 RC00135,RC00354 ko00000,ko00001,ko01000 Bacteria 2GJ0U@201174,4DRK2@85009,COG2423@1,COG2423@2 NA|NA|NA E Ornithine cyclodeaminase/mu-crystallin family gnl|extdb|FAM19036-p1-1.1_000044 1171373.PACID_32070 1e-81 309.3 Propionibacteriales ptpA GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 2IM0Q@201174,4DR9C@85009,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family gnl|extdb|FAM19036-p1-1.1_000045 1171373.PACID_32060 0.0 1114.0 Propionibacteriales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4DPYM@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM19036-p1-1.1_000048 1171373.PACID_32030 0.0 1272.3 Propionibacteriales 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 2GKC3@201174,4DP98@85009,COG0737@1,COG0737@2 NA|NA|NA F 5'-nucleotidase, C-terminal domain gnl|extdb|FAM19036-p1-1.1_000049 1171373.PACID_32020 0.0 1164.1 Actinobacteria treA 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,COG0366@1,COG0366@2 NA|NA|NA G alpha amylase, catalytic gnl|extdb|FAM19036-p1-1.1_000050 1171373.PACID_32000 8.7e-143 513.1 Propionibacteriales ko:K10119 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GNQW@201174,4DUCB@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000051 1171373.PACID_31990 3.2e-164 584.3 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GKJI@201174,4DWRG@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000053 1171373.PACID_31970 2.2e-205 721.5 Actinobacteria Bacteria 2GNFJ@201174,COG1940@1,COG1940@2 NA|NA|NA GK ROK family gnl|extdb|FAM19036-p1-1.1_000054 1171373.PACID_31960 2.5e-278 964.1 Propionibacteriales ko:K03929 ko00000,ko01000 CE10 Bacteria 2GJCN@201174,4DNPT@85009,COG2272@1,COG2272@2 NA|NA|NA I Carboxylesterase family gnl|extdb|FAM19036-p1-1.1_000056 1171373.PACID_31940 7.7e-137 493.4 Actinobacteria Bacteria 2F8FT@1,2I7S1@201174,340UH@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000057 1171373.PACID_31930 2e-124 451.8 Actinobacteria mgtC ko:K07507 ko00000,ko02000 9.B.20 Bacteria 2GJF0@201174,COG1285@1,COG1285@2 NA|NA|NA S PFAM MgtC SapB transporter gnl|extdb|FAM19036-p1-1.1_000058 1171373.PACID_31910 7.6e-169 599.7 Actinobacteria ugpA ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GKJI@201174,COG1175@1,COG1175@2 NA|NA|NA G PFAM binding-protein-dependent transport systems inner membrane component gnl|extdb|FAM19036-p1-1.1_000060 1171373.PACID_31890 1.2e-263 915.2 Actinobacteria ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 2ICW1@201174,COG1653@1,COG1653@2 NA|NA|NA G ABC transporter substrate-binding protein gnl|extdb|FAM19036-p1-1.1_000061 1171373.PACID_31880 1.2e-222 778.9 Bacteria Bacteria COG1524@1,COG1524@2 NA|NA|NA S mannose-ethanolamine phosphotransferase activity gnl|extdb|FAM19036-p1-1.1_000062 1171373.PACID_31860 0.0 1417.9 Actinobacteria bgl2 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 2GJ5H@201174,COG1472@1,COG1472@2 NA|NA|NA G hydrolase, family 3 gnl|extdb|FAM19036-p1-1.1_000063 1171373.PACID_31840 0.0 1681.8 Actinobacteria 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 2GP4V@201174,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family gnl|extdb|FAM19036-p1-1.1_000064 1171373.PACID_31830 4.1e-269 933.7 Propionibacteriales acm 3.2.1.17 ko:K01185,ko:K07273 ko00000,ko01000 Bacteria 2GKS0@201174,4DNA2@85009,COG3757@1,COG3757@2,COG5479@1,COG5479@2 NA|NA|NA M Glycosyl hydrolases family 25 gnl|extdb|FAM19036-p1-1.1_000065 1171373.PACID_31820 1.7e-162 578.6 Actinobacteria 3.5.1.105 ko:K03478 ko00000,ko01000 Bacteria 2I8JK@201174,COG3394@1,COG3394@2 NA|NA|NA G YdjC-like protein gnl|extdb|FAM19036-p1-1.1_000067 1171373.PACID_31800 0.0 1222.2 Propionibacteriales malL 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 2GKS4@201174,4DPT7@85009,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain gnl|extdb|FAM19036-p1-1.1_000068 1171373.PACID_31790 1.4e-187 662.1 Propionibacteriales Bacteria 2GJV7@201174,4DT3I@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_000069 1171373.PACID_31780 0.0 2263.4 Actinobacteria Bacteria 2ICNN@201174,COG3979@1,COG3979@2 NA|NA|NA G chitinase gnl|extdb|FAM19036-p1-1.1_000070 1171373.PACID_31780 2.8e-16 90.5 Actinobacteria Bacteria 2ICNN@201174,COG3979@1,COG3979@2 NA|NA|NA G chitinase gnl|extdb|FAM19036-p1-1.1_000071 1171373.PACID_31770 8e-225 786.2 Propionibacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GM4E@201174,4DQVH@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_000072 1171373.PACID_31760 9.4e-234 815.8 Propionibacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GM4E@201174,4DQVH@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_000073 1171373.PACID_31750 6e-170 603.6 Propionibacteriales thuF ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10237,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00204,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GM6N@201174,4DNTC@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000074 1171373.PACID_31740 6.2e-160 570.1 Propionibacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GKEE@201174,4DMZB@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000075 1171373.PACID_31730 3e-104 384.4 Actinobacteria Bacteria 2I63M@201174,COG2911@1,COG2911@2 NA|NA|NA G Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_000076 1171373.PACID_31720 1.1e-178 632.5 Actinobacteria ko:K09155 ko00000 Bacteria 2H9GN@201174,COG2461@1,COG2461@2 NA|NA|NA S hemerythrin HHE cation binding domain gnl|extdb|FAM19036-p1-1.1_000078 1171373.PACID_31690 4.5e-129 467.2 Actinobacteria Bacteria 2GPT2@201174,COG2345@1,COG2345@2 NA|NA|NA K IclR helix-turn-helix domain gnl|extdb|FAM19036-p1-1.1_000079 1171373.PACID_31680 1.6e-131 475.3 Actinobacteria 3.5.1.28 ko:K11066,ko:K12287 ko00000,ko01000,ko01011,ko02044 Bacteria 2I6U6@201174,COG3023@1,COG3023@2 NA|NA|NA V N-acetylmuramoyl-L-alanine amidase gnl|extdb|FAM19036-p1-1.1_000082 1171373.PACID_31560 0.0 1100.9 Actinobacteria fruA 3.2.1.26,3.2.1.65,3.2.1.80 ko:K01193,ko:K01212,ko:K03332 ko00051,ko00052,ko00500,ko01100,map00051,map00052,map00500,map01100 R00801,R00802,R00879,R02410,R03635,R03921,R05624,R06088,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 GH32 Bacteria 2GJ9T@201174,COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family gnl|extdb|FAM19036-p1-1.1_000083 1171373.PACID_31550 4e-117 427.6 Propionibacteriales Bacteria 2GIZ3@201174,4DPSU@85009,COG1814@1,COG1814@2 NA|NA|NA S VIT family gnl|extdb|FAM19036-p1-1.1_000084 1171373.PACID_31540 7.3e-121 439.9 Propionibacteriales Bacteria 2GN73@201174,4DQR7@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM19036-p1-1.1_000085 1171373.PACID_31530 2.1e-169 601.7 Actinobacteria Bacteria 2H8CD@201174,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor gnl|extdb|FAM19036-p1-1.1_000086 1171373.PACID_31520 3.3e-143 514.6 Actinobacteria apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 2GN6F@201174,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein gnl|extdb|FAM19036-p1-1.1_000089 1171373.PACID_31480 3.2e-261 907.5 Propionibacteriales Bacteria 2GU7G@201174,4DQSY@85009,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases gnl|extdb|FAM19036-p1-1.1_000090 1171373.PACID_31470 1.1e-125 456.1 Actinobacteria ko:K07090 ko00000 Bacteria 2GJCC@201174,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM19036-p1-1.1_000091 367299.JOEE01000006_gene755 9.3e-214 749.6 Intrasporangiaceae hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GP6Y@201174,4FG4F@85021,COG0286@1,COG0286@2 NA|NA|NA V HsdM N-terminal domain gnl|extdb|FAM19036-p1-1.1_000092 326424.FRAAL3318 5.6e-65 255.0 Actinobacteria hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 2IN0M@201174,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain gnl|extdb|FAM19036-p1-1.1_000094 443906.CMM_2901 7.7e-69 268.9 Bacteria Bacteria 2EWNF@1,33Q0C@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000097 1120934.KB894442_gene4193 1.7e-08 65.5 Actinobacteria Bacteria 28W32@1,2GZII@201174,2ZI3Y@2 NA|NA|NA S Protein of unknown function (DUF2283) gnl|extdb|FAM19036-p1-1.1_000100 1176165.CAJD01000007_gene155 6.1e-168 597.0 Brevibacteriaceae Bacteria 2IAJ1@201174,4FATA@85019,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain gnl|extdb|FAM19036-p1-1.1_000101 1370125.AUWT01000029_gene735 1.3e-58 232.6 Mycobacteriaceae ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 23AGT@1762,2ID5E@201174,COG1487@1,COG1487@2 NA|NA|NA S Domain of unknown function (DUF4411) gnl|extdb|FAM19036-p1-1.1_000102 585531.HMPREF0063_11125 0.0 1328.9 Actinobacteria hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2I2FC@201174,COG4096@1,COG4096@2 NA|NA|NA L Type III restriction enzyme res subunit gnl|extdb|FAM19036-p1-1.1_000103 223184.AS25_13045 1.9e-24 119.0 Micrococcaceae Bacteria 1WA3S@1268,2GRAD@201174,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain gnl|extdb|FAM19036-p1-1.1_000104 1171373.PACID_31450 0.0 1366.7 Propionibacteriales pacS GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2GIRF@201174,4DPNE@85009,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase gnl|extdb|FAM19036-p1-1.1_000107 1171373.PACID_31420 1.4e-289 1001.5 Propionibacteriales ybdK_1 Bacteria 2GKCT@201174,4DNRR@85009,COG2170@1,COG2170@2 NA|NA|NA S glutamate--cysteine ligase gnl|extdb|FAM19036-p1-1.1_000108 1171373.PACID_31410 3.6e-93 347.4 Actinobacteria Bacteria 2IHR8@201174,COG3832@1,COG3832@2 NA|NA|NA S Activator of hsp90 atpase 1 family protein gnl|extdb|FAM19036-p1-1.1_000109 1171373.PACID_31400 1.4e-53 215.3 Bacteria Bacteria COG0640@1,COG0640@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM19036-p1-1.1_000110 1171373.PACID_31390 0.0 1693.3 Propionibacteriales 2.4.1.64 ko:K05342 ko00500,ko01100,map00500,map01100 R02727 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 2GKEV@201174,4DNX8@85009,COG1554@1,COG1554@2 NA|NA|NA G Glycosyl hydrolase family 65 central catalytic domain gnl|extdb|FAM19036-p1-1.1_000112 1171373.PACID_31370 1.5e-117 429.1 Propionibacteriales ehuC ko:K02029,ko:K09971 ko02010,map02010 M00232,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 Bacteria 2GJJ9@201174,4DQBU@85009,COG0765@1,COG0765@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000113 1171373.PACID_31360 1.8e-108 398.7 Actinobacteria ehuD ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GM0I@201174,COG0765@1,COG0765@2 NA|NA|NA E amino acid ABC transporter gnl|extdb|FAM19036-p1-1.1_000114 1171373.PACID_31350 1.5e-132 478.8 Actinobacteria 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2GIZW@201174,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein gnl|extdb|FAM19036-p1-1.1_000117 1171373.PACID_31330 8.2e-133 479.9 Propionibacteriales 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 Bacteria 2HRMA@201174,4DSII@85009,COG3473@1,COG3473@2 NA|NA|NA Q Catalyzes the conversion of maleate to fumarate gnl|extdb|FAM19036-p1-1.1_000118 1171373.PACID_31320 1.3e-171 609.0 Propionibacteriales Bacteria 2GP09@201174,4DRRR@85009,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain gnl|extdb|FAM19036-p1-1.1_000119 1171373.PACID_31310 3.4e-237 827.4 Propionibacteriales 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GKPZ@201174,4DTAR@85009,COG0154@1,COG0154@2 NA|NA|NA J Amidase gnl|extdb|FAM19036-p1-1.1_000120 1171373.PACID_31300 1.4e-92 345.5 Propionibacteriales MA20_34860 ko:K09143 ko00000 Bacteria 2I8JP@201174,4DSWZ@85009,COG2164@1,COG2164@2 NA|NA|NA S Protein of unknown function (DUF3830) gnl|extdb|FAM19036-p1-1.1_000121 1171373.PACID_31290 2.3e-136 491.5 Actinobacteria cypM_2 Bacteria 2I7S0@201174,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain gnl|extdb|FAM19036-p1-1.1_000122 1171373.PACID_31280 7.7e-72 276.9 Actinobacteria Bacteria 2EQJT@1,2IDGV@201174,33I5T@2 NA|NA|NA S AbiEi antitoxin C-terminal domain gnl|extdb|FAM19036-p1-1.1_000123 1171373.PACID_31270 2.1e-137 495.0 Actinobacteria Bacteria 2H4TG@201174,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system gnl|extdb|FAM19036-p1-1.1_000124 1171373.PACID_31260 1.2e-266 925.2 Propionibacteriales gabD3 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4DNDH@85009,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_000125 1171373.PACID_31250 2e-244 851.3 Propionibacteriales gabT 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GIS9@201174,4DTQT@85009,COG0160@1,COG0160@2 NA|NA|NA E Aminotransferase class-III gnl|extdb|FAM19036-p1-1.1_000126 1171373.PACID_31240 1.5e-124 452.2 Propionibacteriales Bacteria 2GMZ9@201174,4DRKH@85009,COG1802@1,COG1802@2 NA|NA|NA K FCD gnl|extdb|FAM19036-p1-1.1_000127 1171373.PACID_31230 1.4e-239 835.1 Propionibacteriales eutD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.4.13.9,3.5.4.44 ko:K01271,ko:K15783 ko00260,ko01100,map00260,map01100 R09800 RC02661 ko00000,ko00001,ko01000,ko01002 Bacteria 2GM7D@201174,4DUSQ@85009,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain gnl|extdb|FAM19036-p1-1.1_000128 1171373.PACID_31220 4.6e-238 830.1 Propionibacteriales ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 R01939 RC00006 ko00000,ko00001,ko01000 Bacteria 2GITW@201174,4DPAN@85009,COG1167@1,COG1167@2 NA|NA|NA EK Alanine-glyoxylate amino-transferase gnl|extdb|FAM19036-p1-1.1_000129 1171373.PACID_31210 1.1e-220 772.3 Propionibacteriales argE 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8IJ@201174,4DRD4@85009,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain gnl|extdb|FAM19036-p1-1.1_000130 1171373.PACID_31200 6.5e-265 919.5 Propionibacteriales proP ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,4DPQY@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM19036-p1-1.1_000131 1171373.PACID_31170 1.2e-266 925.2 Actinobacteria fucA 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 2I650@201174,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase gnl|extdb|FAM19036-p1-1.1_000132 1171373.PACID_31160 1.6e-232 811.6 Propionibacteriales Bacteria 2GNN6@201174,4DQEC@85009,COG3934@1,COG3934@2 NA|NA|NA G Belongs to the glycosyl hydrolase 5 (cellulase A) family gnl|extdb|FAM19036-p1-1.1_000133 1171373.PACID_31150 0.0 2103.2 Propionibacteriales 3.2.1.24 ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 GH38 Bacteria 2GM02@201174,4DPRM@85009,COG0383@1,COG0383@2 NA|NA|NA G Alpha mannosidase, middle domain gnl|extdb|FAM19036-p1-1.1_000135 1171373.PACID_31130 1.3e-281 975.3 Propionibacteriales 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMMA@201174,4DUG3@85009,COG1232@1,COG1232@2 NA|NA|NA H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX gnl|extdb|FAM19036-p1-1.1_000136 1171373.PACID_31120 2.7e-197 694.5 Propionibacteriales pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GK3W@201174,4DNN1@85009,COG1071@1,COG1071@2 NA|NA|NA C dehydrogenase, E1 component gnl|extdb|FAM19036-p1-1.1_000138 1171373.PACID_31100 1.9e-217 761.9 Propionibacteriales pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GM0D@201174,4DPHS@85009,COG0508@1,COG0508@2 NA|NA|NA C e3 binding domain gnl|extdb|FAM19036-p1-1.1_000139 1171373.PACID_31090 1.2e-75 290.4 Actinobacteria Bacteria 2GR5S@201174,COG5164@1,COG5164@2 NA|NA|NA K Domain of unknown function (DUF4282) gnl|extdb|FAM19036-p1-1.1_000141 1171373.PACID_31070 1.4e-116 425.6 Propionibacteriales Bacteria 28MIG@1,2IGFB@201174,2ZAV8@2,4DQAF@85009 NA|NA|NA S EcsC protein family gnl|extdb|FAM19036-p1-1.1_000142 1171373.PACID_31060 2.8e-156 557.8 Propionibacteriales aat 2.3.2.6 ko:K00684 R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 Bacteria 2IFT7@201174,4DQD7@85009,COG2360@1,COG2360@2 NA|NA|NA O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine gnl|extdb|FAM19036-p1-1.1_000144 1171373.PACID_31040 5.9e-177 626.7 Propionibacteriales pheA 1.3.1.12,4.2.1.51,5.4.99.5 ko:K04517,ko:K04518,ko:K14170 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQ5@201174,4DN8Z@85009,COG0077@1,COG0077@2 NA|NA|NA E Prephenate dehydratase gnl|extdb|FAM19036-p1-1.1_000146 1171373.PACID_31020 6.9e-242 842.8 Propionibacteriales serS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIWP@201174,4DNQN@85009,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) gnl|extdb|FAM19036-p1-1.1_000148 1171373.PACID_31000 1.9e-272 944.5 Propionibacteriales bglA 3.2.1.21,3.2.1.23 ko:K01190,ko:K05350 ko00052,ko00460,ko00500,ko00511,ko00600,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00511,map00600,map00940,map01100,map01110 R00026,R01105,R01678,R02558,R02887,R02985,R03355,R03527,R04783,R04949,R04998,R06114,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00452,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 Bacteria 2GJAF@201174,4DP9T@85009,COG2723@1,COG2723@2,COG3934@1,COG3934@2 NA|NA|NA G Glycosyl hydrolase family 1 gnl|extdb|FAM19036-p1-1.1_000149 1171373.PACID_31000 0.0 1312.0 Propionibacteriales bglA 3.2.1.21,3.2.1.23 ko:K01190,ko:K05350 ko00052,ko00460,ko00500,ko00511,ko00600,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00511,map00600,map00940,map01100,map01110 R00026,R01105,R01678,R02558,R02887,R02985,R03355,R03527,R04783,R04949,R04998,R06114,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00452,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 Bacteria 2GJAF@201174,4DP9T@85009,COG2723@1,COG2723@2,COG3934@1,COG3934@2 NA|NA|NA G Glycosyl hydrolase family 1 gnl|extdb|FAM19036-p1-1.1_000150 1171373.PACID_30990 1.7e-148 531.9 Propionibacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJ5X@201174,4DT19@85009,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000151 1171373.PACID_30980 1.5e-167 595.5 Actinobacteria ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GJ70@201174,COG1175@1,COG1175@2 NA|NA|NA G PFAM binding-protein-dependent transport systems inner membrane component gnl|extdb|FAM19036-p1-1.1_000152 1171373.PACID_30970 1.7e-206 725.3 Actinobacteria ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GZ1E@201174,COG1653@1,COG1653@2 NA|NA|NA G solute-binding protein gnl|extdb|FAM19036-p1-1.1_000153 1171373.PACID_30950 1.3e-148 532.7 Propionibacteriales Bacteria 2GJHF@201174,4DNQJ@85009,COG1609@1,COG1609@2 NA|NA|NA K periplasmic binding protein LacI transcriptional regulator gnl|extdb|FAM19036-p1-1.1_000154 1171373.PACID_30940 4.1e-147 527.3 Propionibacteriales Bacteria 2GP42@201174,4DQHS@85009,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase gnl|extdb|FAM19036-p1-1.1_000155 1171373.PACID_30930 8.9e-84 316.2 Bacteria Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation gnl|extdb|FAM19036-p1-1.1_000156 1171373.PACID_30920 0.0 1171.4 Actinobacteria nhaP ko:K03316 ko00000 2.A.36 Bacteria 2I9RZ@201174,COG0025@1,COG0025@2 NA|NA|NA P Sodium/hydrogen exchanger family gnl|extdb|FAM19036-p1-1.1_000157 1171373.PACID_30910 1.5e-217 761.9 Propionibacteriales Bacteria 2GK22@201174,4DQEZ@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000158 1171373.PACID_30900 3.1e-275 953.7 Propionibacteriales argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iSBO_1134.SBO_3210,iSbBS512_1146.SbBS512_E3599 Bacteria 2GK96@201174,4DNHA@85009,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 2 subfamily gnl|extdb|FAM19036-p1-1.1_000159 1171373.PACID_30890 3.7e-190 670.6 Propionibacteriales qor 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 2GN47@201174,4DNH8@85009,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase gnl|extdb|FAM19036-p1-1.1_000165 1171373.PACID_30810 1.8e-195 688.3 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4DNIR@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_000169 1171373.PACID_30770 1.8e-127 461.8 Propionibacteriales Bacteria 2GJ4I@201174,4DVK3@85009,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family gnl|extdb|FAM19036-p1-1.1_000171 1171373.PACID_30750 1.1e-133 482.6 Propionibacteriales glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2GNM5@201174,4DRS8@85009,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase gnl|extdb|FAM19036-p1-1.1_000172 1171373.PACID_30740 0.0 1211.8 Propionibacteriales yuxL 3.4.19.1 ko:K01303 ko00000,ko01000,ko01002 Bacteria 2GMMM@201174,4DPKW@85009,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU WD40-like Beta Propeller Repeat gnl|extdb|FAM19036-p1-1.1_000173 1171373.PACID_30730 2.1e-188 664.8 Propionibacteriales yfmJ ko:K07119 ko00000 Bacteria 2GKR8@201174,4DNKF@85009,COG2130@1,COG2130@2 NA|NA|NA S N-terminal domain of oxidoreductase gnl|extdb|FAM19036-p1-1.1_000174 1171373.PACID_30710 0.0 1337.0 Propionibacteriales 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 2IA2H@201174,4DWT2@85009,COG0296@1,COG0296@2 NA|NA|NA G Alpha amylase, C-terminal all-beta domain gnl|extdb|FAM19036-p1-1.1_000176 1171373.PACID_30690 9.2e-92 342.8 Propionibacteriales ybaK ko:K03976,ko:K19055 ko00000,ko01000,ko03016 Bacteria 2GKUX@201174,4DR3S@85009,COG2606@1,COG2606@2 NA|NA|NA S Aminoacyl-tRNA editing domain gnl|extdb|FAM19036-p1-1.1_000177 1122998.AUHZ01000011_gene539 3.6e-85 321.6 Propionibacteriales 4.2.1.153,4.2.1.56 ko:K09709,ko:K18291 ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200 M00376 R02491,R09282 RC00730,RC02479 ko00000,ko00001,ko00002,ko01000 Bacteria 2HF9K@201174,4DRXZ@85009,COG3777@1,COG3777@2 NA|NA|NA S 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity gnl|extdb|FAM19036-p1-1.1_000178 1171373.PACID_30650 1e-116 426.0 Propionibacteriales upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 Bacteria 2GPJE@201174,4DPRI@85009,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate gnl|extdb|FAM19036-p1-1.1_000185 1171373.PACID_30530 1.8e-289 1001.1 Propionibacteriales Bacteria 2GN1H@201174,4DP8S@85009,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM19036-p1-1.1_000186 1171373.PACID_30520 8.8e-171 606.3 Propionibacteriales proWY ko:K05845 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GJWY@201174,4DNRX@85009,COG1732@1,COG1732@2 NA|NA|NA M Substrate binding domain of ABC-type glycine betaine transport system gnl|extdb|FAM19036-p1-1.1_000187 1171373.PACID_30510 5e-114 417.2 Propionibacteriales ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GYTC@201174,4DQDG@85009,COG1174@1,COG1174@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000188 1171373.PACID_30500 1.6e-101 375.6 Propionibacteriales ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GMU0@201174,4DQQZ@85009,COG1174@1,COG1174@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000189 1171373.PACID_30490 1.6e-200 705.3 Propionibacteriales ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GJHI@201174,4DPZM@85009,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter gnl|extdb|FAM19036-p1-1.1_000190 1171373.PACID_30470 2.3e-268 931.0 Propionibacteriales ko:K11105 ko00000,ko02000 2.A.36.6 Bacteria 2GJ9B@201174,4DN3N@85009,COG3263@1,COG3263@2 NA|NA|NA P TrkA-C domain gnl|extdb|FAM19036-p1-1.1_000191 1171373.PACID_30460 5.3e-82 310.5 Actinobacteria Bacteria 2E1BJ@1,2GXNF@201174,32WRF@2 NA|NA|NA S LytR cell envelope-related transcriptional attenuator gnl|extdb|FAM19036-p1-1.1_000192 1171373.PACID_30450 2.4e-49 201.1 Propionibacteriales Bacteria 2IKJX@201174,32SQA@2,4DR6N@85009,COG5450@1 NA|NA|NA K Transcription regulator of the Arc MetJ class gnl|extdb|FAM19036-p1-1.1_000193 1171373.PACID_30440 5e-277 959.9 Propionibacteriales yjgR ko:K06915 ko00000 Bacteria 2GM12@201174,4DNQR@85009,COG0433@1,COG0433@2 NA|NA|NA M Bacterial protein of unknown function (DUF853) gnl|extdb|FAM19036-p1-1.1_000195 1171373.PACID_30420 3.1e-139 501.1 Bacteria Bacteria COG2852@1,COG2852@2 NA|NA|NA L Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_000196 1171373.PACID_30410 4e-47 193.7 Bacteria azlD Bacteria COG1687@1,COG1687@2 NA|NA|NA E Branched-chain amino acid transport protein (AzlD) gnl|extdb|FAM19036-p1-1.1_000197 1171373.PACID_30400 3.6e-137 494.2 Propionibacteriales azlC Bacteria 2IFI6@201174,4DRFF@85009,COG1296@1,COG1296@2 NA|NA|NA E AzlC protein gnl|extdb|FAM19036-p1-1.1_000198 1171373.PACID_30380 6.2e-185 653.7 Bacteria puhA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 ko:K13991 ko02020,map02020 ko00000,ko00001,ko00194 Bacteria COG3861@1,COG3861@2 NA|NA|NA S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity gnl|extdb|FAM19036-p1-1.1_000199 1171373.PACID_30370 6.1e-112 410.2 Actinobacteria rlpA ko:K03642,ko:K21688 ko00000 Bacteria 2GSPY@201174,COG0797@1,COG0797@2 NA|NA|NA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides gnl|extdb|FAM19036-p1-1.1_000200 1171373.PACID_30360 4.1e-279 966.8 Propionibacteriales Bacteria 2I6Q0@201174,4DX27@85009,COG5479@1,COG5479@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase gnl|extdb|FAM19036-p1-1.1_000201 1121933.AUHH01000067_gene2023 8.9e-13 80.9 Bacteria Bacteria 2ETYI@1,33MFN@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000202 1171373.PACID_30340 3e-75 287.7 Actinobacteria Bacteria 2IMQ7@201174,COG1942@1,COG1942@2 NA|NA|NA S tautomerase gnl|extdb|FAM19036-p1-1.1_000203 1171373.PACID_30330 1.7e-169 602.1 Propionibacteriales 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2HZ7D@201174,4DQDY@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM19036-p1-1.1_000204 1171373.PACID_30320 1.8e-176 625.2 Propionibacteriales Bacteria 2IAXV@201174,4DQBH@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold gnl|extdb|FAM19036-p1-1.1_000205 1171373.PACID_30310 2.3e-164 584.7 Propionibacteriales tesB ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 2GJ1B@201174,4DN4N@85009,COG1946@1,COG1946@2 NA|NA|NA I Acyl-CoA thioesterase gnl|extdb|FAM19036-p1-1.1_000206 754252.PFREUD_22470 1.5e-183 649.4 Propionibacteriales dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0030246,GO:0042221,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 2.7.1.121,2.7.1.209,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K20901 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059,R11460 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJV9@201174,4DN06@85009,COG2376@1,COG2376@2 NA|NA|NA G Dihydroxyacetone kinase gnl|extdb|FAM19036-p1-1.1_000207 1171373.PACID_30290 5.8e-194 683.3 Actinobacteria 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC7@201174,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_000208 1171373.PACID_30280 2.6e-107 394.8 Propionibacteriales deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 R01066 RC00436,RC00437 ko00000,ko00001,ko01000 iSB619.SA_RS00835 Bacteria 2GJIR@201174,4DRHH@85009,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate gnl|extdb|FAM19036-p1-1.1_000209 1171373.PACID_30270 3.9e-165 587.4 Actinobacteria ko:K05346 ko00000,ko03000 Bacteria 2GMIM@201174,COG2390@1,COG2390@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_000211 1171373.PACID_30250 0.0 1088.6 Propionibacteriales Bacteria 2I41D@201174,4DQK0@85009,COG1069@1,COG1069@2 NA|NA|NA G FGGY family of carbohydrate kinases, N-terminal domain gnl|extdb|FAM19036-p1-1.1_000212 1171373.PACID_30090 1.2e-121 442.6 Propionibacteriales ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 2GMHX@201174,4DSGT@85009,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) gnl|extdb|FAM19036-p1-1.1_000213 1171373.PACID_30080 7.1e-147 526.6 Bacteria GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria COG0671@1,COG0671@2 NA|NA|NA I phosphatidate phosphatase activity gnl|extdb|FAM19036-p1-1.1_000214 1171373.PACID_30070 4.6e-152 543.9 Propionibacteriales uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJVG@201174,4DQ00@85009,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin gnl|extdb|FAM19036-p1-1.1_000215 1171373.PACID_30060 3.9e-119 434.1 Propionibacteriales Bacteria 2GN73@201174,4DQR7@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM19036-p1-1.1_000216 1171373.PACID_30050 1.2e-159 569.3 Propionibacteriales Bacteria 2H8CD@201174,4DQEI@85009,COG0642@1,COG2205@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain gnl|extdb|FAM19036-p1-1.1_000217 1171373.PACID_30040 1.4e-217 761.9 Actinobacteria Bacteria 2GIZG@201174,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 gnl|extdb|FAM19036-p1-1.1_000218 1171373.PACID_30030 0.0 1235.3 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups gnl|extdb|FAM19036-p1-1.1_000219 1171373.PACID_30020 1.4e-81 309.3 Propionibacteriales dedA ko:K03975 ko00000 Bacteria 2GKGR@201174,4DWRJ@85009,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein gnl|extdb|FAM19036-p1-1.1_000222 1122997.AUDD01000026_gene1222 1.5e-150 539.3 Actinobacteria vraB 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GM29@201174,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family gnl|extdb|FAM19036-p1-1.1_000223 1121334.KB911066_gene1015 3.1e-78 298.5 Ruminococcaceae MA20_34180 ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00436 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 Bacteria 1TRM6@1239,248CG@186801,3WHGU@541000,COG1116@1,COG1116@2 NA|NA|NA P ABC transporter gnl|extdb|FAM19036-p1-1.1_000225 1121334.KB911066_gene1013 1.5e-106 392.9 Clostridia MA20_34190 ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UYBA@1239,24D4Q@186801,COG0715@1,COG0715@2 NA|NA|NA P TIGRFAM ABC transporter, substrate-binding protein, aliphatic gnl|extdb|FAM19036-p1-1.1_000226 1423734.JCM14202_30 4.6e-82 311.6 Bacilli 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TQ7W@1239,4HDEC@91061,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM19036-p1-1.1_000227 1121334.KB911066_gene1011 1.1e-36 159.5 Clostridia ko:K09128 ko00000 Bacteria 1V4V4@1239,24Z1C@186801,COG1786@1,COG1786@2 NA|NA|NA S Protein of unknown function DUF126 gnl|extdb|FAM19036-p1-1.1_000228 1105031.HMPREF1141_1992 1.1e-169 602.8 Clostridiaceae ko:K09123 ko00000 Bacteria 1UJDG@1239,24DTH@186801,36GZJ@31979,COG1679@1,COG1679@2 NA|NA|NA S Protein of unknown function (DUF521) gnl|extdb|FAM19036-p1-1.1_000229 1089453.GOSPT_042_00520 6.6e-128 464.2 Gordoniaceae atzC 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 Bacteria 2GKKM@201174,4GAP9@85026,COG0402@1,COG0402@2 NA|NA|NA F Amidohydrolase family gnl|extdb|FAM19036-p1-1.1_000230 1463820.JOGW01000025_gene2825 3.9e-56 224.6 Actinobacteria Bacteria 29129@1,2IG4P@201174,2ZNPT@2 NA|NA|NA S Protein of unknown function (DUF1097) gnl|extdb|FAM19036-p1-1.1_000233 1171373.PACID_29850 8.8e-108 396.4 Actinobacteria Bacteria 2H5Y7@201174,COG1540@1,COG1540@2 NA|NA|NA S 5-oxoprolinase (ATP-hydrolyzing) activity gnl|extdb|FAM19036-p1-1.1_000234 1171373.PACID_29840 4.8e-204 716.8 Actinobacteria Bacteria 28IW2@1,2IA78@201174,2Z8UC@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000235 1171373.PACID_29830 6e-123 446.8 Propionibacteriales Bacteria 2GJ2N@201174,4DNTM@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM19036-p1-1.1_000238 1386089.N865_18660 2.6e-23 115.9 Intrasporangiaceae Bacteria 2I8QG@201174,4FHDG@85021,COG0642@1,COG2205@2 NA|NA|NA T Domain of unknown function (DUF4118) gnl|extdb|FAM19036-p1-1.1_000239 1171373.PACID_29790 2e-210 738.4 Propionibacteriales ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 2GP5W@201174,4DQR2@85009,COG2807@1,COG2807@2 NA|NA|NA P Major Facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000241 1171373.PACID_29770 2.8e-29 134.0 Bacteria chaB ko:K06197 ko00000 Bacteria COG4572@1,COG4572@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000242 1171373.PACID_29750 2.3e-32 144.4 Propionibacteriales Bacteria 2DPE5@1,2IQE8@201174,331QG@2,4DS9W@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000243 1171373.PACID_29740 4.4e-41 173.3 Propionibacteriales Bacteria 2DJKR@1,2I86F@201174,32YT5@2,4DSW1@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000245 1171373.PACID_29720 0.0 1494.9 Propionibacteriales katG GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006282,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009893,GO:0009987,GO:0010035,GO:0010604,GO:0016020,GO:0016209,GO:0016491,GO:0016675,GO:0016677,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019219,GO:0019222,GO:0020012,GO:0020037,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0036094,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043168,GO:0043207,GO:0044237,GO:0044248,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045739,GO:0045935,GO:0046677,GO:0046906,GO:0048037,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0051186,GO:0051187,GO:0051287,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0060255,GO:0065007,GO:0070301,GO:0070402,GO:0070404,GO:0070887,GO:0071236,GO:0071944,GO:0072593,GO:0075136,GO:0080090,GO:0080134,GO:0080135,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1901700,GO:1901701,GO:1990748,GO:2001020,GO:2001022 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 Bacteria 2GJFP@201174,4DNVX@85009,COG0376@1,COG0376@2 NA|NA|NA P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity gnl|extdb|FAM19036-p1-1.1_000246 1171373.PACID_29710 4.9e-53 213.8 Propionibacteriales Bacteria 2DMMR@1,2IQA6@201174,32SHV@2,4DRR1@85009 NA|NA|NA S Putative Actinobacterial Holin-X, holin superfamily III gnl|extdb|FAM19036-p1-1.1_000248 1171373.PACID_29690 2.8e-45 187.6 Propionibacteriales Bacteria 2E5JX@1,2GRDA@201174,330B5@2,4DS5C@85009 NA|NA|NA S Protein of unknown function (DUF4235) gnl|extdb|FAM19036-p1-1.1_000249 1171373.PACID_29680 4.2e-187 660.6 Propionibacteriales rbn ko:K03466,ko:K07058 ko00000,ko03036 3.A.12 Bacteria 2GM6P@201174,4DP5Z@85009,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB gnl|extdb|FAM19036-p1-1.1_000250 882086.SacxiDRAFT_2044 2e-58 232.6 Pseudonocardiales Bacteria 29WM0@1,2HRZT@201174,30I7P@2,4EBJQ@85010 NA|NA|NA S PFAM Transposase DDE domain gnl|extdb|FAM19036-p1-1.1_000251 1171373.PACID_29660 8.2e-148 529.6 Propionibacteriales Bacteria 2GKT2@201174,4DQTC@85009,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM19036-p1-1.1_000252 1171373.PACID_29650 6e-94 350.1 Propionibacteriales dps ko:K04047 ko00000,ko03036 Bacteria 2IFDP@201174,4DQZR@85009,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family gnl|extdb|FAM19036-p1-1.1_000253 1171373.PACID_29640 6.1e-224 783.1 Propionibacteriales 1.18.1.3,1.7.1.15 ko:K00362,ko:K00529 ko00071,ko00360,ko00910,ko01120,ko01220,map00071,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R02000,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJKT@201174,4DTQP@85009,COG0446@1,COG0446@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase gnl|extdb|FAM19036-p1-1.1_000254 1171373.PACID_29630 1.4e-164 585.5 Propionibacteriales Bacteria 2GJU1@201174,4DWNK@85009,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain gnl|extdb|FAM19036-p1-1.1_000255 1171373.PACID_29620 2.2e-245 854.4 Propionibacteriales cypC 1.11.2.4,1.14.14.1 ko:K00493,ko:K15629 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 R03629,R04121,R05259,R09740 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 Bacteria 2GKHM@201174,4DQNX@85009,COG2124@1,COG2124@2 NA|NA|NA Q Cytochrome P450 gnl|extdb|FAM19036-p1-1.1_000256 1171373.PACID_29610 6.7e-181 639.8 Propionibacteriales ligD GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJPX@201174,4DPAG@85009,COG3285@1,COG3285@2 NA|NA|NA L DNA polymerase LigD polymerase domain gnl|extdb|FAM19036-p1-1.1_000257 1171373.PACID_29590 7.8e-88 329.7 Actinobacteria ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2IQ78@201174,COG0834@1,COG0834@2 NA|NA|NA ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain gnl|extdb|FAM19036-p1-1.1_000258 1171373.PACID_29580 7.7e-183 646.4 Actinobacteria 2.5.1.105 ko:K04088,ko:K06897 ko00790,map00790 M00742 R10339 RC00121 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKPR@201174,COG0053@1,COG0053@2 NA|NA|NA P Co Zn Cd cation transporters gnl|extdb|FAM19036-p1-1.1_000259 1171373.PACID_29570 0.0 1384.8 Propionibacteriales katE 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 Bacteria 2GITN@201174,4DP8F@85009,COG0753@1,COG0753@2 NA|NA|NA P Serves to protect cells from the toxic effects of hydrogen peroxide gnl|extdb|FAM19036-p1-1.1_000260 1171373.PACID_29560 1.3e-119 435.6 Propionibacteriales ko:K02282 ko00000,ko02035,ko02044 Bacteria 2IJB1@201174,4DR8P@85009,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_000262 1171373.PACID_29540 0.0 1110.9 Propionibacteriales nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 2GKIK@201174,4DNTA@85009,COG3004@1,COG3004@2 NA|NA|NA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons gnl|extdb|FAM19036-p1-1.1_000269 1171373.PACID_29470 1e-116 426.0 Bacteria hom 1.1.1.3,1.1.1.399,1.1.1.95,2.7.4.1,2.7.6.5,3.1.7.2,4.3.1.19 ko:K00003,ko:K00058,ko:K00937,ko:K01139,ko:K01754 ko00190,ko00230,ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,map00190,map00230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018 M00017,M00018,M00020,M00570 R00220,R00336,R00429,R00996,R01513,R01773,R01775 RC00002,RC00031,RC00078,RC00087,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019,ko04147 Bacteria COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance gnl|extdb|FAM19036-p1-1.1_000270 1171373.PACID_29460 2.1e-272 944.5 Actinobacteria norM ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2HXQ6@201174,COG0534@1,COG0534@2 NA|NA|NA V Na -driven multidrug efflux pump gnl|extdb|FAM19036-p1-1.1_000271 1171373.PACID_29450 1.6e-105 388.7 Propionibacteriales polC 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IB3N@201174,4DWQX@85009,COG0847@1,COG0847@2 NA|NA|NA L EXOIII gnl|extdb|FAM19036-p1-1.1_000272 1171373.PACID_29440 2.5e-135 488.0 Propionibacteriales cobB ko:K12410 ko00000,ko01000 Bacteria 2IJ46@201174,4DQQ7@85009,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form gnl|extdb|FAM19036-p1-1.1_000273 1171373.PACID_29430 0.0 1122.1 Propionibacteriales ko:K09384 ko00000 Bacteria 2H3MV@201174,4DQ1P@85009,COG0507@1,COG0507@2,COG1112@1,COG1112@2 NA|NA|NA L Nuclease-related domain gnl|extdb|FAM19036-p1-1.1_000274 1171373.PACID_29420 0.0 1943.7 Propionibacteriales rpoD ko:K03086 ko00000,ko03021 Bacteria 2GK3Z@201174,4DN2F@85009,COG0568@1,COG0568@2,COG1061@1,COG1061@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth gnl|extdb|FAM19036-p1-1.1_000275 1171373.PACID_29410 4.3e-112 410.6 Propionibacteriales frcK ko:K02173 ko00000 Bacteria 2I9H4@201174,4DR2H@85009,COG0572@1,COG0572@2 NA|NA|NA F Fructose transport system kinase gnl|extdb|FAM19036-p1-1.1_000276 1171373.PACID_29400 8.4e-306 1055.4 Propionibacteriales Bacteria 2I41D@201174,4DQK0@85009,COG1069@1,COG1069@2 NA|NA|NA G FGGY family of carbohydrate kinases, N-terminal domain gnl|extdb|FAM19036-p1-1.1_000277 1171373.PACID_29390 1.6e-176 625.2 Actinobacteria aes GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008126,GO:0008150,GO:0008152,GO:0009056,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0034338,GO:0043086,GO:0043433,GO:0044092,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050790,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0051336,GO:0051346,GO:0052689,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K01066 ko00000,ko01000 Bacteria 2GKX2@201174,COG0657@1,COG0657@2 NA|NA|NA I Alpha beta hydrolase gnl|extdb|FAM19036-p1-1.1_000278 1171373.PACID_29380 4.8e-63 246.9 Propionibacteriales fkbP 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2IHQC@201174,4DQUT@85009,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans gnl|extdb|FAM19036-p1-1.1_000279 1171373.PACID_29370 3.1e-150 537.7 Bacteria yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 ko:K09861 ko00000 Bacteria COG3022@1,COG3022@2 NA|NA|NA S response to hydroperoxide gnl|extdb|FAM19036-p1-1.1_000280 1171373.PACID_29360 6.7e-266 922.9 Actinobacteria phoN Bacteria 2I3WQ@201174,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily gnl|extdb|FAM19036-p1-1.1_000281 1171373.PACID_29350 1.1e-192 679.1 Actinobacteria Bacteria 2I90K@201174,COG4402@1,COG4402@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2330) gnl|extdb|FAM19036-p1-1.1_000283 1171373.PACID_29330 1.9e-197 694.9 Propionibacteriales dppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GIXV@201174,4DT32@85009,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily gnl|extdb|FAM19036-p1-1.1_000284 1171373.PACID_29320 1.9e-181 641.7 Propionibacteriales oppC ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GJ9E@201174,4DUIF@85009,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000285 1171373.PACID_29310 1.7e-152 545.4 Propionibacteriales dppB ko:K02033,ko:K13890,ko:K15581,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00348,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.11,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GJ2C@201174,4DTQF@85009,COG0601@1,COG0601@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000286 1171373.PACID_29300 0.0 1114.4 Actinobacteria ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GIUH@201174,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter substrate-binding protein gnl|extdb|FAM19036-p1-1.1_000287 1171373.PACID_29280 1.7e-67 262.3 Actinobacteria 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 2IS8M@201174,COG4894@1,COG4894@2 NA|NA|NA S Scramblase gnl|extdb|FAM19036-p1-1.1_000288 1171373.PACID_29270 3.9e-96 357.5 Actinobacteria 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 2IS8M@201174,COG4894@1,COG4894@2 NA|NA|NA S Scramblase gnl|extdb|FAM19036-p1-1.1_000289 1171373.PACID_29260 1.7e-96 358.6 Bacteria 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria COG4894@1,COG4894@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000290 1171373.PACID_29250 8.4e-111 406.4 Actinobacteria Bacteria 2B21Q@1,2IMTW@201174,31UIJ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000291 1171373.PACID_29240 1.1e-110 406.4 Bacteria effR Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM19036-p1-1.1_000292 1171373.PACID_29230 1.9e-172 611.7 Propionibacteriales mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWK@201174,4DQ81@85009,COG2040@1,COG2040@2 NA|NA|NA E Homocysteine S-methyltransferase gnl|extdb|FAM19036-p1-1.1_000293 1171373.PACID_29220 5.8e-264 916.4 Propionibacteriales mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K11733,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10,2.A.3.1.2 Bacteria 2I2DX@201174,4DWZH@85009,COG0833@1,COG0833@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM19036-p1-1.1_000298 1171373.PACID_29170 0.0 1474.5 Propionibacteriales pon1 2.4.1.129,2.7.11.1,3.4.16.4 ko:K05365,ko:K05366,ko:K12132 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01001,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4DPA4@85009,COG0744@1,COG0744@2,COG2815@1,COG2815@2 NA|NA|NA M Transglycosylase gnl|extdb|FAM19036-p1-1.1_000299 1292373.H640_01373 3.1e-39 167.5 Propionibacteriales whiB4 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0030312,GO:0043254,GO:0044087,GO:0044464,GO:0047134,GO:0048037,GO:0050789,GO:0050794,GO:0051128,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071944,GO:0090034,GO:0097159,GO:1901363 ko:K18955 ko00000,ko03000 Bacteria 2CC1Y@1,2IQEP@201174,32TCV@2,4DRQS@85009 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA gnl|extdb|FAM19036-p1-1.1_000300 1171373.PACID_29150 6e-27 125.9 Propionibacteriales Bacteria 2E3JZ@1,2GQIX@201174,32YI8@2,4DS7G@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000301 1171373.PACID_29140 5.1e-70 270.4 Propionibacteriales yabJ Bacteria 2IHNE@201174,4DQIS@85009,COG0251@1,COG0251@2 NA|NA|NA J YjgF/chorismate_mutase-like, putative endoribonuclease gnl|extdb|FAM19036-p1-1.1_000302 1171373.PACID_29130 1.4e-111 409.1 Propionibacteriales crp GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 2GMPN@201174,4DMXW@85009,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein gnl|extdb|FAM19036-p1-1.1_000304 1171373.PACID_29110 6.8e-92 343.6 Bacteria ko:K02199 ko00000,ko03110 Bacteria COG0526@1,COG0526@2 NA|NA|NA CO cell redox homeostasis gnl|extdb|FAM19036-p1-1.1_000306 1171373.PACID_29090 3.2e-78 297.7 Propionibacteriales Bacteria 2DPPE@1,2IN30@201174,332VJ@2,4DSE1@85009 NA|NA|NA S Putative Actinobacterial Holin-X, holin superfamily III gnl|extdb|FAM19036-p1-1.1_000307 1171373.PACID_29080 4.4e-143 513.8 Bacteria Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase gnl|extdb|FAM19036-p1-1.1_000308 1171373.PACID_29070 3e-190 671.0 Propionibacteriales ko:K03593 ko00000,ko03029,ko03036 Bacteria 2I2TA@201174,4DQT2@85009,COG0489@1,COG0489@2 NA|NA|NA D protein tyrosine kinase activity gnl|extdb|FAM19036-p1-1.1_000309 1171373.PACID_29060 1.8e-240 838.2 Propionibacteriales cpaF ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GKKJ@201174,4DN5K@85009,COG4962@1,COG4962@2 NA|NA|NA U Type II/IV secretion system protein gnl|extdb|FAM19036-p1-1.1_000311 1171373.PACID_29040 1.3e-123 449.1 Bacteria gspF ko:K12510,ko:K12511 ko00000,ko02044 Bacteria COG2064@1,COG2064@2 NA|NA|NA NU Type II secretion system (T2SS), protein F gnl|extdb|FAM19036-p1-1.1_000313 1171373.PACID_29020 1.4e-45 188.7 Actinobacteria GO:0008150,GO:0010941,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044531,GO:0044532,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0060548,GO:0065007 Bacteria 2EGB2@1,2GT7C@201174,33A2X@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000314 1171373.PACID_29010 4.8e-56 223.8 Bacteria Bacteria 2DRBM@1,33B4F@2 NA|NA|NA S TIGRFAM helicase secretion neighborhood TadE-like protein gnl|extdb|FAM19036-p1-1.1_000316 1171373.PACID_28990 1.2e-227 795.4 Actinobacteria Bacteria 2GQVV@201174,COG4637@1,COG4637@2 NA|NA|NA GM ATP-binding protein gnl|extdb|FAM19036-p1-1.1_000317 882082.SaccyDRAFT_2672 1.1e-19 102.4 Actinobacteria ko:K06893 ko00000 Bacteria 2IHRJ@201174,COG3631@1,COG3631@2 NA|NA|NA S Ketosteroid isomerase-related protein gnl|extdb|FAM19036-p1-1.1_000318 882082.SaccyDRAFT_2672 1.7e-26 125.6 Actinobacteria ko:K06893 ko00000 Bacteria 2IHRJ@201174,COG3631@1,COG3631@2 NA|NA|NA S Ketosteroid isomerase-related protein gnl|extdb|FAM19036-p1-1.1_000319 1171373.PACID_28960 1.6e-39 168.3 Actinobacteria Bacteria 2EBXP@1,2I70R@201174,335X1@2 NA|NA|NA S Antitoxin component of a toxin-antitoxin (TA) module gnl|extdb|FAM19036-p1-1.1_000320 1171373.PACID_28950 2.6e-39 167.5 Propionibacteriales ko:K06218 ko00000,ko02048 Bacteria 2IRES@201174,4DVZ9@85009,COG2026@1,COG2026@2 NA|NA|NA DJ ParE toxin of type II toxin-antitoxin system, parDE gnl|extdb|FAM19036-p1-1.1_000321 1171373.PACID_28940 8.2e-57 226.1 Actinobacteria vapB43 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 2.1.1.63 ko:K10778 ko00000,ko01000,ko03000,ko03400 Bacteria 2H0ZR@201174,COG3905@1,COG3905@2 NA|NA|NA K Ribbon-helix-helix protein, copG family gnl|extdb|FAM19036-p1-1.1_000322 1171373.PACID_28930 1.1e-43 182.2 Actinobacteria Bacteria 2DZ3F@1,2GYRG@201174,34CAH@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000324 1171373.PACID_28900 1.5e-288 998.0 Propionibacteriales rsmC ko:K00612 ko00000,ko01000 Bacteria 2GJPP@201174,4DNCS@85009,COG2890@1,COG2890@2 NA|NA|NA J Methyltransferase small domain gnl|extdb|FAM19036-p1-1.1_000325 1171373.PACID_28890 1.3e-50 205.3 Actinobacteria Bacteria 2GS7C@201174,COG4309@1,COG4309@2 NA|NA|NA S Uncharacterized conserved protein (DUF2249) gnl|extdb|FAM19036-p1-1.1_000326 1171373.PACID_28880 0.0 1741.1 Propionibacteriales topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJU7@201174,4DN7K@85009,COG0550@1,COG0550@2,COG1754@1,COG1754@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone gnl|extdb|FAM19036-p1-1.1_000327 1032480.MLP_49660 4.6e-54 219.2 Bacteria ygiF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.1.25 ko:K18446 ko00000,ko01000 Bacteria COG3025@1,COG3025@2 NA|NA|NA S triphosphatase activity gnl|extdb|FAM19036-p1-1.1_000328 1171373.PACID_28860 2.4e-90 338.6 Propionibacteriales tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNTI@201174,4DNXP@85009,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis gnl|extdb|FAM19036-p1-1.1_000330 1171373.PACID_28840 5.4e-139 500.4 Actinobacteria ko:K15977 ko00000 Bacteria 2GV27@201174,COG2259@1,COG2259@2 NA|NA|NA S DoxX gnl|extdb|FAM19036-p1-1.1_000334 1171373.PACID_28800 0.0 1156.4 Propionibacteriales Bacteria 2GMUR@201174,4DPPG@85009,COG4805@1,COG4805@2 NA|NA|NA S Bacterial protein of unknown function (DUF885) gnl|extdb|FAM19036-p1-1.1_000336 1171373.PACID_28780 2.6e-117 427.9 Propionibacteriales Bacteria 2HQ3W@201174,4DVFA@85009,COG5516@1,COG5516@2 NA|NA|NA S Putative stress-induced transcription regulator gnl|extdb|FAM19036-p1-1.1_000339 1171373.PACID_28750 3.2e-253 880.6 Propionibacteriales 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK23@201174,4DP12@85009,COG1231@1,COG1231@2 NA|NA|NA E amine oxidase gnl|extdb|FAM19036-p1-1.1_000340 1171373.PACID_28740 1.8e-101 375.2 Propionibacteriales Bacteria 2GNFR@201174,4DQXC@85009,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase gnl|extdb|FAM19036-p1-1.1_000343 1171373.PACID_28710 1.1e-161 575.9 Actinobacteria pabC 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GN5Z@201174,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase gnl|extdb|FAM19036-p1-1.1_000344 1171373.PACID_28700 0.0 1163.7 Propionibacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GNKN@201174,4DPH8@85009,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle gnl|extdb|FAM19036-p1-1.1_000345 1171373.PACID_28690 8.6e-190 669.5 Propionibacteriales ko:K02033,ko:K12369 ko02010,ko02024,map02010,map02024 M00239,M00324 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GM72@201174,4DPH9@85009,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000346 1171373.PACID_28680 2.6e-153 548.1 Propionibacteriales ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GKAW@201174,4DPB4@85009,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000347 1171373.PACID_28670 1.1e-308 1065.1 Actinobacteria ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,COG1123@1,COG4172@2 NA|NA|NA P ATPase activity gnl|extdb|FAM19036-p1-1.1_000348 1171373.PACID_28660 4.7e-193 680.2 Propionibacteriales ldcA 3.4.17.13 ko:K01297 ko00000,ko01000,ko01002,ko01011 Bacteria 2HFIX@201174,4DUE1@85009,COG1619@1,COG1619@2 NA|NA|NA V LD-carboxypeptidase gnl|extdb|FAM19036-p1-1.1_000349 1171373.PACID_28650 5.4e-75 287.0 Propionibacteriales ko:K03719 ko00000,ko03000,ko03036 Bacteria 2GK3G@201174,4DQJS@85009,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type gnl|extdb|FAM19036-p1-1.1_000350 1171373.PACID_28640 4.1e-164 583.9 Actinobacteria 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 2I4PD@201174,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family gnl|extdb|FAM19036-p1-1.1_000351 1171373.PACID_28630 2.9e-201 707.6 Actinobacteria Bacteria 2DBHC@1,2I9EG@201174,2Z98E@2 NA|NA|NA S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase gnl|extdb|FAM19036-p1-1.1_000352 1171373.PACID_28620 1.1e-152 545.8 Propionibacteriales 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 2I4PD@201174,4DV7Y@85009,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family gnl|extdb|FAM19036-p1-1.1_000353 1171373.PACID_28610 6.2e-117 426.8 Actinobacteria Bacteria 2IFH7@201174,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain gnl|extdb|FAM19036-p1-1.1_000354 1171373.PACID_28600 6.5e-54 216.5 Propionibacteriales glnB ko:K04751 ko02020,map02020 ko00000,ko00001 Bacteria 2IKN1@201174,4DR0Z@85009,COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family gnl|extdb|FAM19036-p1-1.1_000355 1171373.PACID_28590 2.2e-233 814.7 Propionibacteriales amt ko:K03320 ko00000,ko02000 1.A.11 iNJ661.Rv2920c Bacteria 2GIZK@201174,4DNW9@85009,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family gnl|extdb|FAM19036-p1-1.1_000356 1171373.PACID_28580 1.4e-149 535.8 Actinobacteria Bacteria 2GJTM@201174,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM19036-p1-1.1_000358 1171373.PACID_28560 7.6e-88 329.7 Bacteria sixA 3.6.1.55 ko:K03574,ko:K08296 ko00000,ko01000,ko03400 Bacteria COG2062@1,COG2062@2 NA|NA|NA T phosphohistidine phosphatase, SixA gnl|extdb|FAM19036-p1-1.1_000359 1171373.PACID_28550 3.5e-196 690.6 Actinobacteria axeA GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005975,GO:0005976,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009308,GO:0009987,GO:0010383,GO:0010410,GO:0016787,GO:0016788,GO:0016999,GO:0017144,GO:0019213,GO:0019752,GO:0030653,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043645,GO:0044036,GO:0044106,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0045491,GO:0046483,GO:0046555,GO:0046872,GO:0047739,GO:0052689,GO:0071554,GO:0071704,GO:0072338,GO:1901266,GO:1901360,GO:1901564 3.1.1.41 ko:K01060 ko00311,ko01130,map00311,map01130 R03062 RC00020,RC00041 ko00000,ko00001,ko01000 Bacteria 2GNHH@201174,COG3458@1,COG3458@2 NA|NA|NA Q acetyl xylan esterase gnl|extdb|FAM19036-p1-1.1_000360 1171373.PACID_28540 3.9e-187 660.6 Actinobacteria 2.1.1.113 ko:K00590 ko00000,ko01000,ko02048 Bacteria 2I5QP@201174,COG0863@1,COG0863@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family gnl|extdb|FAM19036-p1-1.1_000362 1171373.PACID_28520 1.6e-239 835.1 Propionibacteriales dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2GJPH@201174,4DN2Y@85009,COG2027@1,COG2027@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase gnl|extdb|FAM19036-p1-1.1_000363 1171373.PACID_28510 2.9e-150 538.1 Propionibacteriales tilS GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJR4@201174,4DQ41@85009,COG0037@1,COG0037@2 NA|NA|NA D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine gnl|extdb|FAM19036-p1-1.1_000364 1171373.PACID_28500 1.2e-97 362.5 Propionibacteriales hpt 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GMDZ@201174,4DN1D@85009,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family gnl|extdb|FAM19036-p1-1.1_000365 1171373.PACID_28490 0.0 1236.9 Propionibacteriales ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2GJ4Q@201174,4DP9B@85009,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins gnl|extdb|FAM19036-p1-1.1_000367 1171373.PACID_28470 9.8e-147 526.2 Propionibacteriales folP 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDQ@201174,4DPQM@85009,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives gnl|extdb|FAM19036-p1-1.1_000368 1171373.PACID_28460 9.4e-62 242.7 Actinobacteria folB GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840 R03503,R03504,R11037,R11073 RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 2IHSW@201174,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin gnl|extdb|FAM19036-p1-1.1_000369 1171373.PACID_28450 1.1e-101 375.9 Propionibacteriales folK 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 Bacteria 2H3G6@201174,4DQ88@85009,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) gnl|extdb|FAM19036-p1-1.1_000370 1122138.AQUZ01000014_gene7014 1.2e-14 86.7 Propionibacteriales Bacteria 2DRQG@1,2HZCF@201174,33CMQ@2,4DS2T@85009 NA|NA|NA S Protein of unknown function (DUF3180) gnl|extdb|FAM19036-p1-1.1_000372 1171373.PACID_28420 1.3e-218 765.4 Propionibacteriales nuoD GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00333,ko:K05579,ko:K13378 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GKEZ@201174,4DSY9@85009,COG0649@1,COG0649@2 NA|NA|NA C Belongs to the complex I 49 kDa subunit family gnl|extdb|FAM19036-p1-1.1_000373 1171373.PACID_28410 2.8e-51 207.6 Propionibacteriales lsr Bacteria 2C4MW@1,2IQ6A@201174,32RKK@2,4DRM6@85009 NA|NA|NA S Lsr2 gnl|extdb|FAM19036-p1-1.1_000374 1171373.PACID_28400 0.0 1614.0 Propionibacteriales clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2GJ77@201174,4DPBH@85009,COG0542@1,COG0542@2 NA|NA|NA O C-terminal, D2-small domain, of ClpB protein gnl|extdb|FAM19036-p1-1.1_000376 1292373.H640_01111 1.6e-46 192.2 Propionibacteriales vsr ko:K07458 ko00000,ko01000,ko03400 Bacteria 2IKPY@201174,4DSJ6@85009,COG3727@1,COG3727@2 NA|NA|NA L DNA mismatch endonuclease Vsr gnl|extdb|FAM19036-p1-1.1_000377 1292373.H640_01106 1.3e-234 819.7 Propionibacteriales Bacteria 2I8GF@201174,4DV8E@85009,COG1100@1,COG1100@2 NA|NA|NA L Z1 domain gnl|extdb|FAM19036-p1-1.1_000378 1463854.JOHT01000003_gene5863 1.7e-22 113.6 Actinobacteria Bacteria 2C6HZ@1,2IEAM@201174,32RIB@2 NA|NA|NA S Putative PD-(D/E)XK family member, (DUF4420) gnl|extdb|FAM19036-p1-1.1_000379 1122998.AUHZ01000008_gene1455 3.1e-182 645.2 Actinobacteria Bacteria 28JJU@1,2IFY1@201174,2Z9CS@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000380 1171373.PACID_28360 2.4e-79 302.4 Actinobacteria Bacteria 2DGRS@1,2HATB@201174,2ZX1P@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000381 1292373.H640_01086 2.4e-53 215.7 Bacteria Bacteria 2ES8K@1,33JT9@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000382 1171373.PACID_28370 0.0 1166.4 Actinobacteria Bacteria 28JJU@1,2IFY1@201174,2Z9CS@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000383 1171373.PACID_28360 6.5e-162 576.6 Actinobacteria Bacteria 2DGRS@1,2HATB@201174,2ZX1P@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000384 1292373.H640_01086 1.9e-48 199.5 Bacteria Bacteria 2ES8K@1,33JT9@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000387 1171373.PACID_28320 8.7e-116 422.9 Bacteria ko:K07118 ko00000 Bacteria COG0702@1,COG0702@2 NA|NA|NA GM epimerase gnl|extdb|FAM19036-p1-1.1_000388 1171373.PACID_28310 3.6e-283 980.3 Propionibacteriales Bacteria 2GU7G@201174,4DQSY@85009,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases gnl|extdb|FAM19036-p1-1.1_000389 1171373.PACID_28300 1.2e-273 948.7 Propionibacteriales Bacteria 2GIUM@201174,4DPK1@85009,COG0477@1,COG0477@2 NA|NA|NA P major facilitator superfamily gnl|extdb|FAM19036-p1-1.1_000390 1171373.PACID_28290 2.8e-160 571.2 Propionibacteriales ko:K07071 ko00000 Bacteria 2GJS0@201174,4DQ87@85009,COG1090@1,COG1090@2 NA|NA|NA S Domain of unknown function (DUF1731) gnl|extdb|FAM19036-p1-1.1_000391 1171373.PACID_28280 3.4e-118 431.0 Actinobacteria gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 2GJYG@201174,COG0705@1,COG0705@2 NA|NA|NA NU Rhomboid family gnl|extdb|FAM19036-p1-1.1_000392 1171373.PACID_28270 6.8e-83 313.5 Propionibacteriales pabB 2.6.1.85,2.7.1.48,4.1.3.27 ko:K00876,ko:K01657,ko:K13950 ko00240,ko00400,ko00405,ko00790,ko00983,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00240,map00400,map00405,map00790,map00983,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R00985,R00986,R01548,R01549,R01716,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00010,RC00017,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GTAB@201174,4DWPY@85009,COG0572@1,COG0572@2 NA|NA|NA F uridine kinase gnl|extdb|FAM19036-p1-1.1_000393 1171373.PACID_28260 4.4e-181 640.6 Propionibacteriales tbpA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015888,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0030975,GO:0030976,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0045117,GO:0048037,GO:0050662,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0071702,GO:0071705,GO:0072348,GO:0097159,GO:1901363,GO:1901681 ko:K02064 ko02010,map02010 M00191 ko00000,ko00001,ko00002,ko02000 3.A.1.19 iAPECO1_1312.APECO1_1914,iSFxv_1172.SFxv_0065,iUTI89_1310.UTI89_C0076 Bacteria 2GMWD@201174,4DPM5@85009,COG4143@1,COG4143@2 NA|NA|NA H Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_000394 1171373.PACID_28250 5.2e-301 1039.6 Propionibacteriales thiP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 ko:K02063 ko02010,map02010 M00191 ko00000,ko00001,ko00002,ko02000 3.A.1.19 iAPECO1_1312.APECO1_1915,iECIAI1_1343.ECIAI1_0067,iECO103_1326.ECO103_0068,iECO111_1330.ECO111_0069,iECO26_1355.ECO26_0069,iECOK1_1307.ECOK1_0068,iECS88_1305.ECS88_0072,iECSE_1348.ECSE_0067,iECUMN_1333.ECUMN_0068,iPC815.YPO0521,iSF_1195.SF0062,iSFxv_1172.SFxv_0064,iS_1188.S0064,iUMN146_1321.UM146_23130,iUTI89_1310.UTI89_C0075 Bacteria 2GKDH@201174,4DPNQ@85009,COG1178@1,COG1178@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000395 1171373.PACID_28240 8e-156 556.6 Propionibacteriales fbpC 3.6.3.30,3.6.3.31 ko:K02010,ko:K02052,ko:K02062,ko:K11072 ko02010,ko02024,map02010,map02024 M00190,M00191,M00193,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11,3.A.1.11.1,3.A.1.19 Bacteria 2GJCM@201174,4DPQS@85009,COG3842@1,COG3842@2 NA|NA|NA E ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_000396 1171373.PACID_28230 2.6e-136 491.5 Actinobacteria 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 2HVNP@201174,COG0412@1,COG0412@2 NA|NA|NA Q dienelactone hydrolase gnl|extdb|FAM19036-p1-1.1_000398 1171373.PACID_28210 5.5e-234 816.6 Propionibacteriales hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158 Bacteria 2GJSH@201174,4DNRS@85009,COG0001@1,COG0001@2 NA|NA|NA H Glutamate-1-semialdehyde aminotransferase gnl|extdb|FAM19036-p1-1.1_000400 1171373.PACID_28190 1.2e-130 472.6 Bacteria hemD GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01719,ko:K01749,ko:K02496,ko:K13542,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0187,iSBO_1134.SBO_3815 Bacteria COG1587@1,COG1587@2 NA|NA|NA H uroporphyrinogen-III synthase activity gnl|extdb|FAM19036-p1-1.1_000401 1171373.PACID_28170 6.2e-170 603.6 Propionibacteriales hemC 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMWI@201174,4DN1M@85009,COG0181@1,COG0181@2 NA|NA|NA H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps gnl|extdb|FAM19036-p1-1.1_000402 1171373.PACID_28160 4.6e-263 913.3 Propionibacteriales hemG 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMMA@201174,4DNZH@85009,COG1232@1,COG1232@2 NA|NA|NA H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX gnl|extdb|FAM19036-p1-1.1_000403 1171373.PACID_28150 1.3e-204 718.8 Propionibacteriales hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0016 Bacteria 2GMY6@201174,4DP2Q@85009,COG0407@1,COG0407@2 NA|NA|NA H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III gnl|extdb|FAM19036-p1-1.1_000405 1171373.PACID_28130 0.0 1272.7 Propionibacteriales hemH GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJTQ@201174,4DNBP@85009,COG0276@1,COG0276@2,COG3253@1,COG3253@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX gnl|extdb|FAM19036-p1-1.1_000406 1171373.PACID_28120 3.5e-71 275.0 Propionibacteriales Bacteria 2E5CN@1,2IRF6@201174,3304R@2,4DS88@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000407 1171373.PACID_28110 1.4e-187 662.1 Propionibacteriales disA 2.7.7.85 ko:K07067 ko00000,ko01000 Bacteria 2GJ41@201174,4DNMZ@85009,COG1623@1,COG1623@2 NA|NA|NA L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process gnl|extdb|FAM19036-p1-1.1_000408 1171373.PACID_28100 3.1e-262 910.6 Propionibacteriales radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 2GMQ0@201174,4DNF3@85009,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function gnl|extdb|FAM19036-p1-1.1_000409 1171373.PACID_28090 4.3e-152 543.9 Propionibacteriales Bacteria 2I3FS@201174,4DUVY@85009,COG0500@1,COG0500@2 NA|NA|NA H Methyltransferase domain gnl|extdb|FAM19036-p1-1.1_000410 1171373.PACID_28080 6.6e-124 449.9 Propionibacteriales Bacteria 2DC18@1,2IBBW@201174,2ZCCT@2,4DUJG@85009 NA|NA|NA S Glyoxalase-like domain gnl|extdb|FAM19036-p1-1.1_000411 1171373.PACID_28070 5.9e-157 560.1 Actinobacteria Bacteria 2GJ6E@201174,COG1082@1,COG1082@2 NA|NA|NA G PFAM Xylose isomerase domain protein TIM barrel gnl|extdb|FAM19036-p1-1.1_000414 1171373.PACID_28040 1.7e-189 668.7 Propionibacteriales asd GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3708c Bacteria 2GJJ8@201174,4DNGU@85009,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate gnl|extdb|FAM19036-p1-1.1_000415 1171373.PACID_28030 1.6e-135 488.8 Propionibacteriales proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ7D@201174,4DNEJ@85009,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline gnl|extdb|FAM19036-p1-1.1_000418 1171373.PACID_28010 4e-113 414.1 Propionibacteriales rex GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K01926 ko00000,ko03000 Bacteria 2GMV2@201174,4DPX5@85009,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state gnl|extdb|FAM19036-p1-1.1_000419 1171373.PACID_27990 2.6e-289 1000.7 Propionibacteriales hemD GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 ko:K02302,ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJZ@201174,4DNP0@85009,COG0007@1,COG0007@2,COG1587@1,COG1587@2 NA|NA|NA H Uroporphyrinogen-III synthase HemD gnl|extdb|FAM19036-p1-1.1_000420 1171373.PACID_27980 1.3e-125 455.7 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 3.1.3.3,3.1.3.73 ko:K02226,ko:K22305 ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130 M00122 R00582,R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMXF@201174,4DPM9@85009,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family gnl|extdb|FAM19036-p1-1.1_000423 1171373.PACID_27950 0.0 1100.1 Propionibacteriales resB ko:K07399 ko00000 Bacteria 2GMGH@201174,4DN12@85009,COG1333@1,COG1333@2 NA|NA|NA O ResB-like family gnl|extdb|FAM19036-p1-1.1_000424 1171373.PACID_27940 7e-167 593.2 Propionibacteriales ccsA GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 Bacteria 2GJR1@201174,4DNN5@85009,COG0755@1,COG0755@2 NA|NA|NA O Cytochrome C assembly protein gnl|extdb|FAM19036-p1-1.1_000425 1171373.PACID_27930 1.6e-94 352.1 Bacteria Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation gnl|extdb|FAM19036-p1-1.1_000426 1171373.PACID_27920 1.8e-184 651.7 Actinobacteria Bacteria 2GU3U@201174,COG5401@1,COG5401@2 NA|NA|NA K Sporulation and spore germination gnl|extdb|FAM19036-p1-1.1_000427 1171373.PACID_27910 2.1e-143 515.0 Propionibacteriales ko:K07124 ko00000 Bacteria 2GKJE@201174,4DQMD@85009,COG0300@1,COG0300@2 NA|NA|NA S KR domain gnl|extdb|FAM19036-p1-1.1_000429 1171373.PACID_27890 0.0 1226.5 Propionibacteriales ko:K06994 ko00000 Bacteria 2GIRQ@201174,4DNWE@85009,COG2409@1,COG2409@2 NA|NA|NA S MMPL family gnl|extdb|FAM19036-p1-1.1_000430 1171373.PACID_27880 0.0 1103.6 Propionibacteriales ko:K03316 ko00000 2.A.36 Bacteria 2GIUT@201174,4DPNW@85009,COG0025@1,COG0025@2 NA|NA|NA P Sodium/hydrogen exchanger family gnl|extdb|FAM19036-p1-1.1_000432 1171373.PACID_27860 0.0 1239.9 Propionibacteriales ilvD GO:0003674,GO:0003824,GO:0004160,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1259,iECIAI39_1322.ECIAI39_3015 Bacteria 2GJIJ@201174,4DN1H@85009,COG0129@1,COG0129@2 NA|NA|NA EG Belongs to the IlvD Edd family gnl|extdb|FAM19036-p1-1.1_000433 1171373.PACID_27850 4e-109 401.0 Actinobacteria Bacteria 2FGE6@1,2H9GR@201174,348A9@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000434 1171373.PACID_27840 2e-269 934.5 Propionibacteriales mtr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657 1.8.1.15,1.8.1.4 ko:K00382,ko:K17883 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GNSR@201174,4DPYH@85009,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gnl|extdb|FAM19036-p1-1.1_000435 1171373.PACID_27830 1.2e-182 645.6 Propionibacteriales viuB_2 Bacteria 2GK5X@201174,4DPDD@85009,COG2375@1,COG2375@2 NA|NA|NA P Siderophore-interacting protein gnl|extdb|FAM19036-p1-1.1_000436 1171373.PACID_27820 6.8e-153 546.6 Propionibacteriales 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 2GJ49@201174,4DQ2B@85009,COG1120@1,COG1120@2 NA|NA|NA HP ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_000437 1171373.PACID_27810 8e-141 506.9 Propionibacteriales ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GJ7A@201174,4DP8K@85009,COG4779@1,COG4779@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM19036-p1-1.1_000438 1171373.PACID_27800 4e-169 600.9 Propionibacteriales fepD ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GJB9@201174,4DPB5@85009,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM19036-p1-1.1_000439 1171373.PACID_27790 9.7e-176 622.9 Propionibacteriales ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2IA3G@201174,4DQPF@85009,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein gnl|extdb|FAM19036-p1-1.1_000440 1171373.PACID_27780 4.5e-311 1072.8 Bacteria troA ko:K09815 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 Bacteria COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family gnl|extdb|FAM19036-p1-1.1_000443 1171373.PACID_27750 5e-146 523.9 Propionibacteriales mtsC ko:K09819 M00243 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 2GJ7H@201174,4DTF4@85009,COG1108@1,COG1108@2 NA|NA|NA P ABC 3 transport family gnl|extdb|FAM19036-p1-1.1_000445 1171373.PACID_27730 3.9e-139 500.7 Actinobacteria Bacteria 2IEKU@201174,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family gnl|extdb|FAM19036-p1-1.1_000446 1171373.PACID_27720 8e-175 619.8 Propionibacteriales cobW ko:K02234 ko00000,ko00001 Bacteria 2GKDR@201174,4DQ3X@85009,COG0523@1,COG0523@2 NA|NA|NA S Cobalamin synthesis protein cobW C-terminal domain gnl|extdb|FAM19036-p1-1.1_000447 1171373.PACID_27700 1.7e-23 114.4 Propionibacteriales rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFV@201174,4DS46@85009,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family gnl|extdb|FAM19036-p1-1.1_000451 1171373.PACID_27670 1.3e-23 114.8 Propionibacteriales rpmF ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2DRA3@1,2GQK2@201174,33AVR@2,4DSJG@85009 NA|NA|NA J Ribosomal L32p protein family gnl|extdb|FAM19036-p1-1.1_000452 1171373.PACID_27640 2.9e-37 160.6 Propionibacteriales rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQAT@201174,4DRIY@85009,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family gnl|extdb|FAM19036-p1-1.1_000453 1171373.PACID_27630 2.5e-141 508.1 Propionibacteriales pstB GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005315,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008144,GO:0008150,GO:0008509,GO:0010921,GO:0015075,GO:0015103,GO:0015114,GO:0015291,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035303,GO:0035435,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363 3.6.3.27,3.6.3.55 ko:K02036,ko:K02068,ko:K06857 ko02010,map02010 M00186,M00211,M00222 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.2,3.A.1.6.4,3.A.1.7 iLJ478.TM1261,iSB619.SA_RS06920 Bacteria 2GJQ3@201174,4DN0B@85009,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system gnl|extdb|FAM19036-p1-1.1_000454 1171373.PACID_27620 6.5e-157 560.1 Propionibacteriales pstA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051704,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iJN746.PP_2658,iPC815.YPO4115,iYL1228.KPN_04131,iZ_1308.Z5217 Bacteria 2I2F2@201174,4DPD3@85009,COG0581@1,COG0581@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000455 1171373.PACID_27610 2.1e-156 558.5 Propionibacteriales pstC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0009314,GO:0009628,GO:0010921,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0034220,GO:0035303,GO:0035435,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051704,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iAF987.Gmet_2702,ic_1306.c4652 Bacteria 2GJDA@201174,4DNZF@85009,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane gnl|extdb|FAM19036-p1-1.1_000456 1171373.PACID_27600 5e-173 614.0 Propionibacteriales pstS GO:0002682,GO:0002683,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0015698,GO:0016020,GO:0016036,GO:0030312,GO:0031347,GO:0031348,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035821,GO:0040007,GO:0042594,GO:0043207,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0044464,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071496,GO:0071944,GO:0075136,GO:0080134 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 2GJXD@201174,4DNCV@85009,COG0226@1,COG0226@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import gnl|extdb|FAM19036-p1-1.1_000457 1171373.PACID_27590 9.2e-172 609.4 Propionibacteriales mutT 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574,ko:K08296 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNRV@201174,4DQI9@85009,COG0494@1,COG0494@2,COG2062@1,COG2062@2 NA|NA|NA L Phosphoglycerate mutase family gnl|extdb|FAM19036-p1-1.1_000458 1171373.PACID_27580 0.0 1387.1 Propionibacteriales ppk 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GJ0B@201174,4DNIH@85009,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) gnl|extdb|FAM19036-p1-1.1_000459 1171373.PACID_27570 8e-117 426.4 Propionibacteriales Bacteria 2GJGU@201174,4DN15@85009,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal gnl|extdb|FAM19036-p1-1.1_000460 1171373.PACID_27560 5.9e-177 626.7 Propionibacteriales Bacteria 2E40M@1,2GRE0@201174,32YXE@2,4DSEX@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000461 1171373.PACID_27550 3.3e-91 340.9 Propionibacteriales Bacteria 2IKQP@201174,4DV0V@85009,COG4405@1,COG4405@2 NA|NA|NA S ASCH gnl|extdb|FAM19036-p1-1.1_000462 1171373.PACID_27540 1.4e-150 538.9 Propionibacteriales Bacteria 2GNR5@201174,4DPQW@85009,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase gnl|extdb|FAM19036-p1-1.1_000463 1176165.CAJD01000019_gene1541 3.4e-52 210.7 Actinobacteria Bacteria 2IR8D@201174,COG3339@1,COG3339@2 NA|NA|NA O Conserved Protein gnl|extdb|FAM19036-p1-1.1_000464 1176165.CAJD01000019_gene1540 2.9e-75 288.1 Brevibacteriaceae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKRX@201174,4FAE5@85019,COG0597@1,COG0597@2 NA|NA|NA MU Signal peptidase (SPase) II gnl|extdb|FAM19036-p1-1.1_000465 1176165.CAJD01000019_gene1539 0.0 1149.4 Brevibacteriaceae ko:K12954 ko00000,ko01000 3.A.3 Bacteria 2GIRF@201174,4F95G@85019,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase gnl|extdb|FAM19036-p1-1.1_000466 1032480.MLP_37390 5.4e-59 233.4 Propionibacteriales cmtR GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K21885 ko00000,ko03000 Bacteria 2IMDE@201174,4DS0B@85009,COG0640@1,COG0640@2 NA|NA|NA K Bacterial regulatory protein, arsR family gnl|extdb|FAM19036-p1-1.1_000467 1125718.HMPREF1318_2297 1.4e-51 209.1 Actinobacteria Bacteria 2ES5Q@1,2I8VS@201174,33JQH@2,4D4RB@85005 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000468 1115803.HMPREF1129_2239 2.7e-161 575.1 Actinobacteria Bacteria 2C2JI@1,2GPC5@201174,32VE2@2,4D3B5@85005 NA|NA|NA S Relaxase/Mobilisation nuclease domain gnl|extdb|FAM19036-p1-1.1_000469 1027371.GOALK_060_00870 4.7e-84 317.4 Actinobacteria Bacteria 2C2HK@1,2IH1X@201174,33PEK@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000471 1287475.HMPREF1650_11500 9e-37 159.1 Corynebacteriaceae Bacteria 22QJ0@1653,2EQVZ@1,2ITFR@201174,33IFS@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000472 1121020.JIAG01000004_gene2055 7.4e-24 115.9 Actinobacteria Bacteria 2FI5A@1,2H78A@201174,349Y0@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000473 1121020.JIAG01000004_gene2054 1.7e-260 904.8 Micrococcaceae Bacteria 1WA76@1268,2I8IZ@201174,COG1961@1,COG1961@2 NA|NA|NA L Recombinase gnl|extdb|FAM19036-p1-1.1_000474 1171373.PACID_27540 1.1e-39 168.7 Propionibacteriales Bacteria 2GNR5@201174,4DPQW@85009,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase gnl|extdb|FAM19036-p1-1.1_000475 1171373.PACID_27530 4.4e-250 870.2 Actinobacteria cmr 2.7.4.9 ko:K00943,ko:K08217,ko:K18833 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 br01600,ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.2,2.A.1.21.22 Bacteria 2GJSA@201174,COG2270@1,COG2270@2 NA|NA|NA C Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000478 1410634.JHVD01000007_gene1054 1.6e-09 67.8 Propionibacteriales Bacteria 2B542@1,2HZHK@201174,31XXJ@2,4DSU8@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000479 1171373.PACID_27490 2.8e-98 364.4 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GKGF@201174,4DQW9@85009,COG4044@1,COG4044@2 NA|NA|NA S May play a role in the intracellular transport of hydrophobic ligands gnl|extdb|FAM19036-p1-1.1_000480 1171373.PACID_27480 1.2e-177 629.0 Propionibacteriales ygfZ GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GKP0@201174,4DN39@85009,COG0354@1,COG0354@2 NA|NA|NA S Belongs to the GcvT family gnl|extdb|FAM19036-p1-1.1_000481 1171373.PACID_27470 5.5e-256 889.8 Propionibacteriales wcaJ ko:K03606 ko05111,map05111 ko00000,ko00001 Bacteria 2INA8@201174,4DUPC@85009,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase gnl|extdb|FAM19036-p1-1.1_000482 1171373.PACID_27460 1.9e-149 535.4 Propionibacteriales Bacteria 2GXGF@201174,4DP9F@85009,COG1376@1,COG1376@2,COG3103@1,COG3103@2 NA|NA|NA M L,D-transpeptidase catalytic domain gnl|extdb|FAM19036-p1-1.1_000483 1171373.PACID_27450 0.0 1229.9 Propionibacteriales typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 2GJUJ@201174,4DP68@85009,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA gnl|extdb|FAM19036-p1-1.1_000484 1171373.PACID_27440 2.5e-58 231.1 Bacteria ko:K07171 ko00000,ko01000,ko02048 Bacteria COG2337@1,COG2337@2 NA|NA|NA T Toxic component of a toxin-antitoxin (TA) module gnl|extdb|FAM19036-p1-1.1_000485 1120944.JONS01000048_gene2988 8.8e-17 93.6 Actinobacteria Bacteria 2C03A@1,2GMCC@201174,2Z86B@2,4D6Y3@85005 NA|NA|NA S Domain of unknown function (DUF4291) gnl|extdb|FAM19036-p1-1.1_000486 77635.BISU_0778 1.3e-16 91.7 Bifidobacteriales Bacteria 2EGTM@1,2GWY1@201174,33AJR@2,4D2NX@85004 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000487 1171373.PACID_27410 6.2e-304 1049.3 Propionibacteriales cdr ko:K04085 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Bacteria 2H7WY@201174,4DQ82@85009,COG0446@1,COG0446@2,COG0607@1,COG0607@2 NA|NA|NA T Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM19036-p1-1.1_000488 1171373.PACID_27400 5.4e-40 169.9 Actinobacteria ko:K21600 ko00000,ko03000 Bacteria 2IQ7U@201174,COG1937@1,COG1937@2 NA|NA|NA S protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_000489 1171373.PACID_27390 7.1e-87 327.0 Propionibacteriales Bacteria 2DMMI@1,2IKP6@201174,32SFN@2,4DR24@85009 NA|NA|NA S Protein of unknown function (DUF3151) gnl|extdb|FAM19036-p1-1.1_000490 1171373.PACID_27380 5.7e-163 580.1 Actinobacteria Bacteria 2GX9W@201174,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase gnl|extdb|FAM19036-p1-1.1_000492 1171373.PACID_27360 8.8e-63 246.1 Actinobacteria ko:K19686 ko00000,ko01000,ko02048 Bacteria 2IS39@201174,COG3742@1,COG3742@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase gnl|extdb|FAM19036-p1-1.1_000493 1171373.PACID_27350 4.8e-38 163.3 Actinobacteria vapB30 GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 ko:K19687 ko00000,ko02048 Bacteria 2GW0J@201174,COG4423@1,COG4423@2 NA|NA|NA S regulation of biological process gnl|extdb|FAM19036-p1-1.1_000495 1171373.PACID_27320 3.4e-269 933.7 Propionibacteriales purB 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKBR@201174,4DNYZ@85009,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily gnl|extdb|FAM19036-p1-1.1_000496 1171373.PACID_27310 1.3e-168 599.0 Propionibacteriales oxyR ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 2H6E4@201174,4DRMB@85009,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family gnl|extdb|FAM19036-p1-1.1_000497 1171373.PACID_27300 1.1e-300 1038.5 Propionibacteriales ahpF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 ko:K03387 ko00000,ko01000 Bacteria 2H4AX@201174,4DWPW@85009,COG3634@1,COG3634@2 NA|NA|NA O Pyridine nucleotide-disulphide oxidoreductase gnl|extdb|FAM19036-p1-1.1_000498 1171373.PACID_27290 1.1e-106 392.5 Actinobacteria ahpC GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM74@201174,COG0450@1,COG0450@2 NA|NA|NA O alkyl hydroperoxide reductase gnl|extdb|FAM19036-p1-1.1_000499 1171373.PACID_27280 1.9e-219 768.5 Propionibacteriales purS GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13,6.3.5.3 ko:K01923,ko:K01945,ko:K01952,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04463,R04591 RC00010,RC00064,RC00090,RC00162,RC00166,RC01160 ko00000,ko00001,ko00002,ko01000,ko03000 iYO844.BSU06460 Bacteria 2GK3H@201174,4DP92@85009,COG0152@1,COG0152@2,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM19036-p1-1.1_000500 1171373.PACID_27270 7e-124 449.9 Propionibacteriales purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJY@201174,4DNEU@85009,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM19036-p1-1.1_000501 1171373.PACID_27260 0.0 1135.9 Propionibacteriales sir GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,1.8.7.1 ko:K00366,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00531 R00790,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJRN@201174,4DP25@85009,COG0155@1,COG0155@2 NA|NA|NA C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family gnl|extdb|FAM19036-p1-1.1_000503 1171373.PACID_27240 1.2e-261 908.7 Propionibacteriales ko:K03293,ko:K11738 ko00000,ko02000 2.A.3.1,2.A.3.1.8 Bacteria 2GJ0X@201174,4DTIR@85009,COG1113@1,COG1113@2 NA|NA|NA E COG1113 Gamma-aminobutyrate permease and related permeases gnl|extdb|FAM19036-p1-1.1_000504 1171373.PACID_27230 2.5e-178 631.3 Bacteria ansA GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0033345,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 iECO103_1326.ECO103_1961,iSF_1195.SF1456,iS_1188.S1571,iYL1228.KPN_01203 Bacteria COG0252@1,COG0252@2 NA|NA|NA EJ asparaginase activity gnl|extdb|FAM19036-p1-1.1_000505 1171373.PACID_27220 9.1e-210 736.1 Propionibacteriales yjjL Bacteria 2I2F7@201174,4DN2K@85009,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000506 1171373.PACID_27210 1.8e-187 661.8 Propionibacteriales argK GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 ko:K07588 ko00000,ko01000 Bacteria 2GME8@201174,4DP5N@85009,COG1703@1,COG1703@2 NA|NA|NA E ArgK protein gnl|extdb|FAM19036-p1-1.1_000507 1171373.PACID_27200 0.0 1516.1 Propionibacteriales purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKG6@201174,4DN9Q@85009,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM19036-p1-1.1_000508 1171373.PACID_27190 1.9e-133 481.9 Propionibacteriales hflC Bacteria 2GKFP@201174,4DTAB@85009,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues gnl|extdb|FAM19036-p1-1.1_000509 1171373.PACID_27180 5.9e-140 503.4 Actinobacteria Bacteria 29J5I@1,2I9N8@201174,3062Y@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000511 1171373.PACID_27160 7.4e-180 636.3 Bacteria Bacteria COG2852@1,COG2852@2 NA|NA|NA L Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_000512 1171373.PACID_27150 4.9e-254 883.2 Propionibacteriales argE Bacteria 2GM84@201174,4DMZ8@85009,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain gnl|extdb|FAM19036-p1-1.1_000513 1171373.PACID_27140 1.2e-217 762.3 Propionibacteriales Bacteria 2GMHP@201174,4DNQ2@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000514 1171373.PACID_27130 4.8e-290 1003.0 Propionibacteriales purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GK6I@201174,4DN2S@85009,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine gnl|extdb|FAM19036-p1-1.1_000515 1171373.PACID_27120 1.4e-203 715.3 Propionibacteriales purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 2GJNY@201174,4DMYH@85009,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase gnl|extdb|FAM19036-p1-1.1_000516 1292373.H640_00732 1.1e-19 102.1 Propionibacteriales Bacteria 2EGRW@1,2HZH3@201174,33AI2@2,4DSSH@85009 NA|NA|NA S Protein of unknown function (DUF3073) gnl|extdb|FAM19036-p1-1.1_000517 1171373.PACID_27100 5.1e-181 640.2 Propionibacteriales Bacteria 2GIVB@201174,4DP02@85009,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 gnl|extdb|FAM19036-p1-1.1_000518 1171373.PACID_27090 4.2e-234 817.0 Propionibacteriales gtsA ko:K17315 ko02010,map02010 M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 Bacteria 2HZ6D@201174,4DPBX@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_000519 1171373.PACID_27080 8.6e-162 576.2 Propionibacteriales gtsB ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GJWM@201174,4DPW2@85009,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000520 1171373.PACID_27070 4.7e-160 570.5 Propionibacteriales gtsC ko:K02026,ko:K17317 ko02010,map02010 M00207,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.24,3.A.1.1.30 Bacteria 2GJNN@201174,4DPMB@85009,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000521 1171373.PACID_27060 1.8e-214 751.9 Propionibacteriales ko:K01997,ko:K11956 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GMAY@201174,4DNAX@85009,COG0559@1,COG0559@2 NA|NA|NA P Branched-chain amino acid transport system / permease component gnl|extdb|FAM19036-p1-1.1_000522 1171373.PACID_27050 4.5e-180 637.1 Propionibacteriales livM ko:K01998,ko:K11955 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GJB3@201174,4DNKR@85009,COG4177@1,COG4177@2 NA|NA|NA E Branched-chain amino acid transport system / permease component gnl|extdb|FAM19036-p1-1.1_000523 1171373.PACID_27040 1e-193 682.6 Propionibacteriales natA ko:K01995,ko:K11957 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GMEE@201174,4DN7C@85009,COG0411@1,COG0411@2 NA|NA|NA E Branched-chain amino acid ATP-binding cassette transporter gnl|extdb|FAM19036-p1-1.1_000524 1171373.PACID_27030 8.9e-133 479.6 Propionibacteriales livF ko:K01996,ko:K11958 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GKSQ@201174,4DPW5@85009,COG0410@1,COG0410@2 NA|NA|NA E ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_000525 1171373.PACID_27020 3.4e-204 717.6 Propionibacteriales natB ko:K01999,ko:K11954 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GM00@201174,4DPSP@85009,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region gnl|extdb|FAM19036-p1-1.1_000528 1171373.PACID_26980 4.1e-113 414.1 Actinobacteria ko:K07118 ko00000 Bacteria 2GKNN@201174,COG0702@1,COG0702@2 NA|NA|NA GM epimerase dehydratase gnl|extdb|FAM19036-p1-1.1_000530 1171373.PACID_26960 1.1e-65 258.1 Actinobacteria Bacteria 2I692@201174,COG3103@1,COG3103@2 NA|NA|NA T Sh3 type 3 domain protein gnl|extdb|FAM19036-p1-1.1_000540 443906.CMM_2222 1.6e-37 162.5 Actinobacteria ko:K18831 ko00000,ko02048,ko03000 Bacteria 2IR22@201174,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase gnl|extdb|FAM19036-p1-1.1_000548 446465.Bfae_16880 4.5e-80 305.8 Actinobacteria Bacteria 28NJJ@1,2IBUV@201174,2ZBKQ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000550 408672.NBCG_03013 4.3e-53 215.7 Propionibacteriales Bacteria 2GISN@201174,4DNBK@85009,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family gnl|extdb|FAM19036-p1-1.1_000552 1171373.PACID_26910 2.9e-98 364.4 Bacteria Bacteria COG3832@1,COG3832@2 NA|NA|NA J glyoxalase III activity gnl|extdb|FAM19036-p1-1.1_000554 1171373.PACID_26890 8.7e-256 889.0 Propionibacteriales pvdL ko:K21183 M00827,M00828,M00832 ko00000,ko00001,ko00002 Bacteria 2I19B@201174,4DVU8@85009,COG1020@1,COG1020@2 NA|NA|NA Q Condensation domain gnl|extdb|FAM19036-p1-1.1_000555 1171373.PACID_26880 2e-146 525.0 Actinobacteria Bacteria 2IA2Y@201174,COG0596@1,COG0596@2 NA|NA|NA S Alpha beta hydrolase gnl|extdb|FAM19036-p1-1.1_000556 1171373.PACID_26870 2e-212 745.0 Propionibacteriales tetV ko:K18215 ko00000,ko01504,ko02000 2.A.1.21.3 Bacteria 2GJPT@201174,4DN7I@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000557 1171373.PACID_26860 1.7e-63 248.4 Actinobacteria Bacteria 2DPEX@1,2IR24@201174,331T0@2 NA|NA|NA S Domain of unknown function (DUF4440) gnl|extdb|FAM19036-p1-1.1_000558 935845.JADQ01000004_gene1970 2.7e-75 289.3 Paenibacillaceae bvdR 1.3.1.24 ko:K00214 ko00860,ko01100,ko01110,map00860,map01100,map01110 R02391,R02393 RC01983 ko00000,ko00001,ko01000 Bacteria 1UGN1@1239,26S5V@186822,4HTCD@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold gnl|extdb|FAM19036-p1-1.1_000559 1171373.PACID_26850 1.6e-165 589.0 Actinobacteria ugt 2.4.1.173 ko:K05841 ko00000,ko01000,ko01003 GT1 Bacteria 2GJMF@201174,COG1819@1,COG1819@2 NA|NA|NA CG glycosyl gnl|extdb|FAM19036-p1-1.1_000560 1171373.PACID_26820 2.6e-175 621.3 Propionibacteriales Bacteria 2GIZC@201174,4DPM0@85009,COG2378@1,COG2378@2 NA|NA|NA K Helix-turn-helix type 11 domain protein gnl|extdb|FAM19036-p1-1.1_000561 1171373.PACID_26810 0.0 1552.0 Propionibacteriales uvrA2 Bacteria 2GJUV@201174,4DTER@85009,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter gnl|extdb|FAM19036-p1-1.1_000562 1171373.PACID_26800 1.2e-178 632.5 Propionibacteriales Bacteria 2ECUS@1,2HWUQ@201174,336S8@2,4DVHY@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000564 1171373.PACID_26780 0.0 1652.5 Actinobacteria 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMN4@201174,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate gnl|extdb|FAM19036-p1-1.1_000565 1171373.PACID_26770 1.9e-96 358.6 Propionibacteriales ko:K07118 ko00000 Bacteria 2I234@201174,4DUWN@85009,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family gnl|extdb|FAM19036-p1-1.1_000566 1171373.PACID_26760 4.7e-103 380.6 Propionibacteriales Bacteria 2I03U@201174,4DVHF@85009,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family gnl|extdb|FAM19036-p1-1.1_000567 1171373.PACID_26750 1.9e-86 325.1 Actinobacteria Bacteria 2B3T5@1,2GX8Z@201174,31WGV@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000568 1171373.PACID_26740 5.8e-262 909.8 Propionibacteriales Bacteria 2GU7G@201174,4DQSY@85009,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases gnl|extdb|FAM19036-p1-1.1_000569 1171373.PACID_26720 1e-204 719.2 Actinobacteria fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWD@201174,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) gnl|extdb|FAM19036-p1-1.1_000570 1171373.PACID_26710 1.7e-204 718.4 Actinobacteria mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2I71T@201174,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase gnl|extdb|FAM19036-p1-1.1_000571 1171373.PACID_26700 1.3e-166 592.4 Actinobacteria mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJEH@201174,COG3407@1,COG3407@2 NA|NA|NA I decarboxylase gnl|extdb|FAM19036-p1-1.1_000572 1171373.PACID_26690 1.5e-192 678.7 Actinobacteria mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 2IAQ7@201174,COG1577@1,COG1577@2 NA|NA|NA I mevalonate kinase gnl|extdb|FAM19036-p1-1.1_000574 1122998.AUHZ01000002_gene2053 9.9e-69 266.5 Propionibacteriales ssuE 1.5.1.38 ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 R05706,R07210,R10206 RC00126,RC01779,RC02556 ko00000,ko00001,ko01000 Bacteria 2IHWU@201174,4DQNQ@85009,COG0431@1,COG0431@2 NA|NA|NA S FMN reductase gnl|extdb|FAM19036-p1-1.1_000575 1171373.PACID_26650 9e-181 639.4 Propionibacteriales Bacteria 2H356@201174,4DWKN@85009,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase gnl|extdb|FAM19036-p1-1.1_000576 1171373.PACID_26640 2.6e-146 524.6 Propionibacteriales nagD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 ko:K02566 ko00000 Bacteria 2GJG6@201174,4DPRD@85009,COG0647@1,COG0647@2 NA|NA|NA G Belongs to the HAD-like hydrolase superfamily gnl|extdb|FAM19036-p1-1.1_000577 1171373.PACID_26630 4.5e-288 996.5 Bacteria ko:K07001 ko00000 Bacteria COG1752@1,COG1752@2 NA|NA|NA M Esterase of the alpha-beta hydrolase superfamily gnl|extdb|FAM19036-p1-1.1_000578 1171373.PACID_26620 3.6e-154 550.8 Actinobacteria Bacteria 2CR6U@1,2IRNY@201174,32SNH@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000580 1171373.PACID_26600 1.1e-228 798.9 Actinobacteria galK 2.7.1.157,2.7.1.6 ko:K00849,ko:K18674 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2H2AH@201174,COG0153@1,COG0153@2 NA|NA|NA G Belongs to the GHMP kinase family gnl|extdb|FAM19036-p1-1.1_000583 1171373.PACID_26570 2.1e-71 275.0 Bacteria dhaM GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033554,GO:0033558,GO:0034983,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047324,GO:0050896,GO:0051716,GO:0071704,GO:0098732,GO:0140096,GO:1901564 2.7.1.121,2.7.1.202,2.7.3.9 ko:K02768,ko:K05881,ko:K08483,ko:K11183 ko00051,ko00561,ko01100,ko01120,ko02060,map00051,map00561,map01100,map01120,map02060 M00273 R01012,R03232 RC00015,RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 iECs_1301.ECs1703,iSF_1195.SF1201,iS_1188.S1285,iUTI89_1310.UTI89_C1391,iZ_1308.Z1969 Bacteria COG3412@1,COG3412@2 NA|NA|NA S phosphoenolpyruvate-glycerone phosphotransferase activity gnl|extdb|FAM19036-p1-1.1_000584 1171373.PACID_26560 9.1e-97 359.8 Propionibacteriales dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 R01012 RC00015,RC00017 ko00000,ko00001,ko01000 iECUMN_1333.ECUMN_1495 Bacteria 2HEQ9@201174,4DQSR@85009,COG1461@1,COG1461@2 NA|NA|NA S Dak2 gnl|extdb|FAM19036-p1-1.1_000585 1171373.PACID_26550 1.8e-184 651.7 Propionibacteriales dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 Bacteria 2GJV9@201174,4DN06@85009,COG2376@1,COG2376@2 NA|NA|NA G Dihydroxyacetone kinase gnl|extdb|FAM19036-p1-1.1_000587 1171373.PACID_26530 5.5e-145 520.4 Propionibacteriales menA GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737 Bacteria 2GJBS@201174,4DNAI@85009,COG1575@1,COG1575@2 NA|NA|NA H Belongs to the MenA family. Type 1 subfamily gnl|extdb|FAM19036-p1-1.1_000588 1171373.PACID_26520 2.7e-45 187.6 Bacteria lsrG 5.3.1.32 ko:K11530 ko02024,map02024 ko00000,ko00001,ko01000 Bacteria COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase gnl|extdb|FAM19036-p1-1.1_000589 1171373.PACID_26510 0.0 1126.3 Propionibacteriales exsA ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GJWP@201174,4DWN0@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM19036-p1-1.1_000590 1171373.PACID_26500 0.0 1231.9 Actinobacteria Bacteria 2HF5B@201174,COG2251@1,COG2251@2 NA|NA|NA V RecB family gnl|extdb|FAM19036-p1-1.1_000591 1171373.PACID_26490 1.7e-129 468.8 Propionibacteriales ubiE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0040007,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Bacteria 2GKFZ@201174,4DNP2@85009,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) gnl|extdb|FAM19036-p1-1.1_000592 1171373.PACID_26480 3.4e-112 411.0 Propionibacteriales ccmA 3.6.3.27,3.6.3.55 ko:K01990,ko:K06021,ko:K06857 ko02010,map02010 M00186,M00254 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.6.2,3.A.1.6.4 Bacteria 2IJGC@201174,4DQSV@85009,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM19036-p1-1.1_000594 1171373.PACID_26460 7.2e-65 253.4 Bacteria Bacteria COG2732@1,COG2732@2 NA|NA|NA K (Barnase) inhibitor gnl|extdb|FAM19036-p1-1.1_000596 1171373.PACID_26440 2.1e-69 268.1 Actinobacteria Bacteria 2B4QC@1,2GYZY@201174,31XGN@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000598 1171373.PACID_26420 6.4e-251 872.8 Propionibacteriales 1.3.99.38 ko:K21401 ko00000,ko01000 Bacteria 2GKGH@201174,4DPE1@85009,COG0644@1,COG0644@2 NA|NA|NA C FAD binding domain gnl|extdb|FAM19036-p1-1.1_000599 1171373.PACID_26410 3.9e-60 237.3 Propionibacteriales nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044464,GO:0050136,GO:0055114,GO:0071944,GO:0098796,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IFDT@201174,4DWQZ@85009,COG0838@1,COG0838@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain gnl|extdb|FAM19036-p1-1.1_000600 1171373.PACID_26400 3.9e-107 394.0 Propionibacteriales nuoB 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GJP5@201174,4DWQ1@85009,COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000602 1171373.PACID_26380 2.9e-233 814.3 Propionibacteriales nuoD 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2I5QS@201174,4DWNZ@85009,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000603 1171373.PACID_26370 8.1e-137 493.0 Propionibacteriales nuoE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 ko:K00334,ko:K00335,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 2GKG0@201174,4DN2R@85009,COG1905@1,COG1905@2 NA|NA|NA C Thioredoxin-like [2Fe-2S] ferredoxin gnl|extdb|FAM19036-p1-1.1_000604 1171373.PACID_26360 7.1e-261 906.0 Propionibacteriales nuoF 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GMMC@201174,4DPP6@85009,COG1894@1,COG1894@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain gnl|extdb|FAM19036-p1-1.1_000605 1171373.PACID_26350 0.0 1468.4 Propionibacteriales nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GJGX@201174,4DNGW@85009,COG1034@1,COG1034@2 NA|NA|NA C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region gnl|extdb|FAM19036-p1-1.1_000606 1171373.PACID_26340 2e-218 765.0 Propionibacteriales nuoH 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iNJ661.Rv3152 Bacteria 2GIVY@201174,4DNAD@85009,COG1005@1,COG1005@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone gnl|extdb|FAM19036-p1-1.1_000607 1171373.PACID_26330 1.4e-106 392.1 Propionibacteriales nuoI GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 ko:K00337,ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iNJ661.Rv3153 Bacteria 2GJNU@201174,4DP1W@85009,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000608 1171373.PACID_26320 5.7e-128 463.8 Propionibacteriales nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GKRS@201174,4DPPF@85009,COG0839@1,COG0839@2 NA|NA|NA C Belongs to the complex I subunit 6 family gnl|extdb|FAM19036-p1-1.1_000609 1171373.PACID_26310 1.2e-43 182.2 Propionibacteriales nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340,ko:K05576 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IKV7@201174,4DRR0@85009,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000611 1171373.PACID_26290 3.1e-273 947.2 Propionibacteriales nuoM GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iSDY_1059.SDY_2473 Bacteria 2GKBN@201174,4DPXE@85009,COG1008@1,COG1008@2 NA|NA|NA C Proton-conducting membrane transporter gnl|extdb|FAM19036-p1-1.1_000612 1171373.PACID_26280 1.5e-286 991.5 Propionibacteriales nuoN GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GMGX@201174,4DNIM@85009,COG1007@1,COG1007@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000613 1171373.PACID_26270 1.4e-173 615.5 Propionibacteriales hepS GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 R09247 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 2GMB4@201174,4DNPE@85009,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family gnl|extdb|FAM19036-p1-1.1_000614 1171373.PACID_26260 2.1e-307 1060.8 Propionibacteriales Bacteria 2GIWQ@201174,4DNNH@85009,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM19036-p1-1.1_000615 1171373.PACID_26250 7.1e-267 926.0 Propionibacteriales eutB 4.3.1.7 ko:K03735 ko00564,ko01100,map00564,map01100 R00749 RC00370 ko00000,ko00001,ko01000 Bacteria 2GY0C@201174,4DNW5@85009,COG4303@1,COG4303@2 NA|NA|NA E Ethanolamine ammonia lyase large subunit (EutB) gnl|extdb|FAM19036-p1-1.1_000616 1171373.PACID_26240 3.6e-132 477.6 Propionibacteriales eutC GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0008851,GO:0009350,GO:0016829,GO:0016840,GO:0016841,GO:0019842,GO:0031419,GO:0032991,GO:0036094,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363,GO:1902494 4.3.1.7 ko:K03736 ko00564,ko01100,map00564,map01100 R00749 RC00370 ko00000,ko00001,ko01000 Bacteria 2IB7Y@201174,4DQC4@85009,COG4302@1,COG4302@2 NA|NA|NA E Ethanolamine ammonia-lyase light chain (EutC) gnl|extdb|FAM19036-p1-1.1_000618 1171373.PACID_26220 8.9e-168 596.3 Propionibacteriales ko:K02058 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 2GJ0Z@201174,4DQJY@85009,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein domain gnl|extdb|FAM19036-p1-1.1_000619 1171373.PACID_26210 6e-280 969.5 Propionibacteriales ytfR 3.6.3.17 ko:K02056 M00221 ko00000,ko00002,ko01000,ko02000 3.A.1.2 iECED1_1282.ECED1_5085 Bacteria 2GJ3F@201174,4DNDA@85009,COG1129@1,COG1129@2 NA|NA|NA G ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_000621 1171373.PACID_26190 1.1e-190 672.5 Propionibacteriales yjfF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 iECW_1372.ECW_m4592,iEKO11_1354.EKO11_4080,iWFL_1372.ECW_m4592 Bacteria 2GJDW@201174,4DQ7E@85009,COG1172@1,COG1172@2 NA|NA|NA G Branched-chain amino acid transport system / permease component gnl|extdb|FAM19036-p1-1.1_000622 1171373.PACID_26170 0.0 1378.2 Propionibacteriales pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 2GNJY@201174,4DQ4I@85009,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 gnl|extdb|FAM19036-p1-1.1_000624 1171373.PACID_26150 0.0 1221.1 Propionibacteriales korA 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXV@201174,4DPBE@85009,COG0674@1,COG0674@2,COG1014@1,COG1014@2 NA|NA|NA C ferredoxin oxidoreductase gnl|extdb|FAM19036-p1-1.1_000625 1171373.PACID_26140 5e-78 297.0 Bacteria 1.12.1.2,1.6.5.3 ko:K00331,ko:K18006,ko:K18007 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000626 1171373.PACID_26130 7.6e-91 339.7 Bacteria nuoC 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000627 1171373.PACID_26120 2.6e-63 247.7 Actinobacteria nuoI 1.6.5.3 ko:K00338,ko:K03615,ko:K05580 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GPSS@201174,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000630 1171373.PACID_26090 1.1e-172 612.5 Propionibacteriales exoA 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKIS@201174,4DNS6@85009,COG0708@1,COG0708@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family gnl|extdb|FAM19036-p1-1.1_000631 1171373.PACID_26080 2e-80 305.1 Propionibacteriales trpF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K09767 ko00000 Bacteria 2IFIU@201174,4DQT9@85009,COG1666@1,COG1666@2 NA|NA|NA S Belongs to the UPF0234 family gnl|extdb|FAM19036-p1-1.1_000635 1171373.PACID_26040 1.1e-25 121.7 Actinobacteria rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFG@201174,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family gnl|extdb|FAM19036-p1-1.1_000636 1171373.PACID_26030 3.5e-79 300.8 Propionibacteriales Bacteria 2GMVC@201174,4DRU6@85009,COG2030@1,COG2030@2 NA|NA|NA I N-terminal half of MaoC dehydratase gnl|extdb|FAM19036-p1-1.1_000637 1171373.PACID_26020 2.3e-81 308.1 Propionibacteriales hadB Bacteria 2IFCJ@201174,4DRH0@85009,COG2030@1,COG2030@2 NA|NA|NA I MaoC like domain gnl|extdb|FAM19036-p1-1.1_000638 1171373.PACID_26010 2.3e-223 781.2 Propionibacteriales murB GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 iECED1_1282.ECED1_4683,iECUMN_1333.ECUMN_4498_AT6,iLF82_1304.LF82_1416,iNRG857_1313.NRG857_19845 Bacteria 2GIV2@201174,4DNF7@85009,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation gnl|extdb|FAM19036-p1-1.1_000639 1171373.PACID_26000 2.3e-245 854.4 Propionibacteriales aspT ko:K00375 ko00000,ko03000 Bacteria 2GKVK@201174,4DNSD@85009,COG1167@1,COG1167@2 NA|NA|NA EK Alanine-glyoxylate amino-transferase gnl|extdb|FAM19036-p1-1.1_000641 1171373.PACID_25980 3.9e-79 301.2 Propionibacteriales secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GQFP@201174,4DSA3@85009,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation gnl|extdb|FAM19036-p1-1.1_000642 1171373.PACID_25970 4.1e-154 550.8 Propionibacteriales nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2GJFW@201174,4DPR5@85009,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination gnl|extdb|FAM19036-p1-1.1_000643 1171373.PACID_25960 2.3e-72 278.1 Propionibacteriales rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFCK@201174,4DQC0@85009,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors gnl|extdb|FAM19036-p1-1.1_000644 1171373.PACID_25950 3.2e-124 451.1 Propionibacteriales rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM51@201174,4DNBG@85009,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release gnl|extdb|FAM19036-p1-1.1_000645 1171373.PACID_25940 3.4e-79 301.2 Propionibacteriales rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM0V@201174,4DQF9@85009,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors gnl|extdb|FAM19036-p1-1.1_000646 1171373.PACID_25930 1.8e-44 185.3 Propionibacteriales rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKNW@201174,4DQS8@85009,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation gnl|extdb|FAM19036-p1-1.1_000647 1171373.PACID_25920 0.0 2328.5 Propionibacteriales rpoB GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJ81@201174,4DMYN@85009,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM19036-p1-1.1_000648 1171373.PACID_25910 0.0 2546.5 Propionibacteriales rpoC GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GKWF@201174,4DP2S@85009,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM19036-p1-1.1_000651 1171373.PACID_25880 1.8e-181 641.7 Actinobacteria ygjR GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114,GO:0102497 ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 2IIQ1@201174,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase NAD-binding domain protein gnl|extdb|FAM19036-p1-1.1_000652 1171373.PACID_25870 1.3e-60 238.8 Propionibacteriales rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHUF@201174,4DQR6@85009,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit gnl|extdb|FAM19036-p1-1.1_000653 1171373.PACID_25860 6.6e-81 306.6 Propionibacteriales rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMVW@201174,4DQ8Q@85009,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA gnl|extdb|FAM19036-p1-1.1_000654 1171373.PACID_25850 0.0 1390.6 Propionibacteriales fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 2GKB3@201174,4DNTK@85009,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome gnl|extdb|FAM19036-p1-1.1_000655 1171373.PACID_25830 7.7e-227 792.7 Propionibacteriales tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02358 ko00000,ko03012,ko03029,ko04147 Bacteria 2GK4T@201174,4DP42@85009,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis gnl|extdb|FAM19036-p1-1.1_000656 1171373.PACID_25820 0.0 1260.4 Propionibacteriales Bacteria 2GKB5@201174,4DT2E@85009,COG4425@1,COG4425@2 NA|NA|NA S Alpha/beta-hydrolase family N-terminus gnl|extdb|FAM19036-p1-1.1_000657 1171373.PACID_25810 7.4e-97 359.8 Actinobacteria Bacteria 2II1I@201174,COG2318@1,COG2318@2 NA|NA|NA S Protein of unknown function (DUF664) gnl|extdb|FAM19036-p1-1.1_000658 1171373.PACID_25800 0.0 1135.6 Actinobacteria glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECIAI39_1322.ECIAI39_0637 Bacteria 2H1TZ@201174,COG0008@1,COG0008@2 NA|NA|NA J tRNA synthetases class I (E and Q), anti-codon binding domain gnl|extdb|FAM19036-p1-1.1_000659 1171373.PACID_25780 6.4e-271 939.5 Propionibacteriales gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iNJ661.Rv2992c Bacteria 2GJJS@201174,4DPQP@85009,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gnl|extdb|FAM19036-p1-1.1_000660 1171373.PACID_25770 1.2e-51 208.8 Propionibacteriales rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRA@201174,4DQJR@85009,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes gnl|extdb|FAM19036-p1-1.1_000661 1171373.PACID_25760 2.9e-98 364.8 Propionibacteriales rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJXT@201174,4DNWZ@85009,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit gnl|extdb|FAM19036-p1-1.1_000662 1171373.PACID_25750 2e-158 565.1 Propionibacteriales rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02926 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJYJ@201174,4DN59@85009,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel gnl|extdb|FAM19036-p1-1.1_000663 1171373.PACID_25740 3.7e-48 197.2 Propionibacteriales rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ7V@201174,4DR9N@85009,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome gnl|extdb|FAM19036-p1-1.1_000664 1171373.PACID_25730 1.9e-155 555.1 Propionibacteriales rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK7R@201174,4DN2A@85009,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity gnl|extdb|FAM19036-p1-1.1_000665 1122997.AUDD01000005_gene1817 7.5e-48 196.1 Propionibacteriales rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKMS@201174,4DR2Q@85009,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA gnl|extdb|FAM19036-p1-1.1_000666 1171373.PACID_25710 9.8e-77 292.7 Propionibacteriales rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IM3J@201174,4DQNW@85009,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome gnl|extdb|FAM19036-p1-1.1_000667 1171373.PACID_25700 4.4e-96 357.8 Propionibacteriales rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GKF1@201174,4DNUB@85009,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation gnl|extdb|FAM19036-p1-1.1_000668 1171373.PACID_25690 3.3e-76 290.8 Propionibacteriales rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFEI@201174,4DQ7S@85009,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs gnl|extdb|FAM19036-p1-1.1_000669 1171373.PACID_25680 3.4e-33 147.1 Propionibacteriales rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ6V@201174,4DRUK@85009,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family gnl|extdb|FAM19036-p1-1.1_000670 1171373.PACID_25670 1.3e-41 175.3 Propionibacteriales rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ68@201174,4DRI1@85009,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA gnl|extdb|FAM19036-p1-1.1_000672 1171373.PACID_25650 5.3e-198 696.8 Actinobacteria Bacteria 2GJ5Q@201174,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein LacI transcriptional regulator gnl|extdb|FAM19036-p1-1.1_000673 1171373.PACID_25640 7e-227 793.1 Propionibacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GK2W@201174,4DPBD@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_000674 1171373.PACID_25620 1.5e-156 558.9 Propionibacteriales amyD ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GKJI@201174,4DTAT@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000675 1171373.PACID_25610 2.6e-161 574.7 Propionibacteriales ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 Bacteria 2GITV@201174,4DPGZ@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000676 1171373.PACID_25600 0.0 1612.8 Actinobacteria uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GNMW@201174,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate gnl|extdb|FAM19036-p1-1.1_000677 1171373.PACID_25590 3.2e-62 244.2 Propionibacteriales rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHNX@201174,4DQTB@85009,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome gnl|extdb|FAM19036-p1-1.1_000678 1171373.PACID_25580 1e-60 239.2 Propionibacteriales rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKP2@201174,4DRJP@85009,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit gnl|extdb|FAM19036-p1-1.1_000679 1171373.PACID_25570 2.9e-116 424.5 Propionibacteriales rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW7@201174,4DNUQ@85009,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits gnl|extdb|FAM19036-p1-1.1_000680 1171373.PACID_25560 1.1e-28 131.7 Actinobacteria rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ8R@201174,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site gnl|extdb|FAM19036-p1-1.1_000681 1171373.PACID_25550 8.6e-69 266.2 Propionibacteriales rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHQZ@201174,4DQQ1@85009,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit gnl|extdb|FAM19036-p1-1.1_000682 1171373.PACID_25540 2.4e-95 354.8 Propionibacteriales rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK35@201174,4DNFZ@85009,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center gnl|extdb|FAM19036-p1-1.1_000683 1171373.PACID_25530 1.4e-60 238.8 Propionibacteriales rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKTX@201174,4DR5B@85009,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance gnl|extdb|FAM19036-p1-1.1_000684 1171373.PACID_25520 3.8e-103 380.9 Propionibacteriales rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW8@201174,4DNXT@85009,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body gnl|extdb|FAM19036-p1-1.1_000685 1171373.PACID_25510 9.2e-23 112.1 Propionibacteriales rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQV0@201174,4DSCE@85009,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 gnl|extdb|FAM19036-p1-1.1_000686 1171373.PACID_25500 7.3e-74 283.1 Propionibacteriales rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2II6M@201174,4DQND@85009,COG0200@1,COG0200@2 NA|NA|NA J binds to the 23S rRNA gnl|extdb|FAM19036-p1-1.1_000687 1171373.PACID_25490 2.2e-179 634.8 Actinobacteria appB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ2C@201174,COG0601@1,COG0601@2 NA|NA|NA EP PFAM binding-protein-dependent transport systems inner membrane component gnl|extdb|FAM19036-p1-1.1_000688 1171373.PACID_25480 6.8e-152 543.5 Actinobacteria dppC ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GJ9E@201174,COG1173@1,COG1173@2 NA|NA|NA EP PFAM binding-protein-dependent transport systems inner membrane component gnl|extdb|FAM19036-p1-1.1_000689 1171373.PACID_25470 0.0 1373.6 Propionibacteriales oppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,4DN37@85009,COG1123@1,COG4172@2 NA|NA|NA O Belongs to the ABC transporter superfamily gnl|extdb|FAM19036-p1-1.1_000691 1171373.PACID_25450 4.2e-104 384.0 Bacteria Bacteria 2E7VQ@1,332AI@2 NA|NA|NA S Bacterial PH domain gnl|extdb|FAM19036-p1-1.1_000692 1171373.PACID_25440 2.3e-243 847.8 Propionibacteriales secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 2GJ26@201174,4DN3Y@85009,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently gnl|extdb|FAM19036-p1-1.1_000693 1171373.PACID_25430 5e-99 367.1 Propionibacteriales adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJ7T@201174,4DP2T@85009,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism gnl|extdb|FAM19036-p1-1.1_000694 1171373.PACID_25420 1.3e-159 568.9 Propionibacteriales map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2GKKB@201174,4DNQ9@85009,COG0024@1,COG0024@2 NA|NA|NA J Methionine aminopeptidase gnl|extdb|FAM19036-p1-1.1_000695 1171373.PACID_25410 7.3e-158 563.1 Actinobacteria 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 2I9NK@201174,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_000696 1122997.AUDD01000005_gene1787 6.3e-18 97.1 Propionibacteriales Bacteria 2HP3B@201174,4DSH5@85009,COG4758@1,COG4758@2 NA|NA|NA S Domain of unknown function (DUF1707) gnl|extdb|FAM19036-p1-1.1_000697 1171373.PACID_25390 3.1e-33 147.1 Propionibacteriales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 2IQ4B@201174,4DRMG@85009,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex gnl|extdb|FAM19036-p1-1.1_000698 1171373.PACID_25380 1.8e-13 80.5 Actinobacteria rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GWMH@201174,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family gnl|extdb|FAM19036-p1-1.1_000699 1171373.PACID_25370 2.5e-59 234.6 Propionibacteriales rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHPN@201174,4DQUI@85009,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits gnl|extdb|FAM19036-p1-1.1_000700 1171373.PACID_25360 5.6e-68 263.5 Propionibacteriales rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFFC@201174,4DQ7M@85009,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome gnl|extdb|FAM19036-p1-1.1_000701 1171373.PACID_25350 5.7e-109 400.2 Propionibacteriales rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GIRX@201174,4DP75@85009,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit gnl|extdb|FAM19036-p1-1.1_000702 1171373.PACID_25330 4.4e-186 657.1 Propionibacteriales rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJJ5@201174,4DNW6@85009,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM19036-p1-1.1_000703 1171373.PACID_25320 6.2e-65 253.8 Propionibacteriales rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHV2@201174,4DQBP@85009,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 gnl|extdb|FAM19036-p1-1.1_000704 1171373.PACID_25310 7.5e-233 812.8 Propionibacteriales ko:K14335 ko00000,ko01000,ko01003 GT4 Bacteria 2GNYW@201174,4DPGM@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM19036-p1-1.1_000705 1122998.AUHZ01000002_gene2163 6.6e-71 273.9 Bacteria Bacteria 28U76@1,2ZGCU@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000706 1171373.PACID_25290 2e-126 458.4 Actinobacteria guaA_1 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GNA6@201174,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase gnl|extdb|FAM19036-p1-1.1_000707 1171373.PACID_25280 1.6e-119 435.3 Propionibacteriales sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 2GJV8@201174,4DQ3N@85009,COG0605@1,COG0605@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems gnl|extdb|FAM19036-p1-1.1_000708 1171373.PACID_25270 4.3e-107 394.4 Propionibacteriales ko:K16784,ko:K16785,ko:K16786,ko:K16787,ko:K16927 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GMK1@201174,4DQPM@85009,COG1122@1,COG1122@2 NA|NA|NA P ECF transporter, substrate-specific component gnl|extdb|FAM19036-p1-1.1_000709 1171373.PACID_25260 0.0 1082.0 Actinobacteria ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,COG1122@1,COG1122@2 NA|NA|NA P part of an ABC transporter complex. Responsible for energy coupling to the transport system gnl|extdb|FAM19036-p1-1.1_000710 1171373.PACID_25250 8.8e-216 756.1 Propionibacteriales ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GKHK@201174,4DPHW@85009,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein gnl|extdb|FAM19036-p1-1.1_000711 1171373.PACID_25240 2.7e-88 331.6 Actinobacteria Bacteria 2GSAU@201174,COG1657@1,COG1657@2 NA|NA|NA I PFAM Prenyltransferase squalene oxidase gnl|extdb|FAM19036-p1-1.1_000712 1171373.PACID_25230 2.7e-108 397.9 Propionibacteriales rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2IFG7@201174,4DNX6@85009,COG2813@1,COG2813@2 NA|NA|NA J Ribosomal protein L11 methyltransferase (PrmA) gnl|extdb|FAM19036-p1-1.1_000713 1171373.PACID_25220 2.8e-165 587.8 Propionibacteriales truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2GJ6C@201174,4DPSE@85009,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs gnl|extdb|FAM19036-p1-1.1_000715 1171373.PACID_25200 6.4e-79 300.1 Propionibacteriales Bacteria 2GR49@201174,4DSWQ@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM19036-p1-1.1_000716 1171373.PACID_25190 2.1e-244 851.7 Propionibacteriales Bacteria 2GJSC@201174,4DN0Z@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000717 1171373.PACID_25180 3.6e-67 260.8 Propionibacteriales yccF Bacteria 2IKS5@201174,4DRE0@85009,COG3304@1,COG3304@2 NA|NA|NA S Inner membrane component domain gnl|extdb|FAM19036-p1-1.1_000718 1171373.PACID_25170 1.2e-79 302.4 Propionibacteriales rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFG1@201174,4DQET@85009,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly gnl|extdb|FAM19036-p1-1.1_000719 1171373.PACID_25160 1.8e-87 328.6 Propionibacteriales rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GNDY@201174,4DQN0@85009,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family gnl|extdb|FAM19036-p1-1.1_000720 1171373.PACID_25150 1.1e-124 452.6 Propionibacteriales Bacteria 2I431@201174,4DQIY@85009,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM19036-p1-1.1_000721 1171373.PACID_25140 1.5e-250 871.7 Propionibacteriales glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iAF987.Gmet_1886,iLJ478.TM0184,iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 2GN87@201174,4DNFP@85009,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gnl|extdb|FAM19036-p1-1.1_000723 1171373.PACID_25120 1.1e-186 659.1 Propionibacteriales coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 2GIRR@201174,4DPFH@85009,COG1072@1,COG1072@2 NA|NA|NA H pantothenate kinase activity gnl|extdb|FAM19036-p1-1.1_000724 1171373.PACID_25110 9e-150 536.2 Propionibacteriales Bacteria 2GK7A@201174,4DP7U@85009,COG0500@1,COG2226@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family gnl|extdb|FAM19036-p1-1.1_000725 1171373.PACID_25100 0.0 1210.7 Propionibacteriales glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 2GKH0@201174,4DNBT@85009,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gnl|extdb|FAM19036-p1-1.1_000726 1171373.PACID_25090 6.5e-57 226.5 Propionibacteriales acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQF6@201174,4DRCQ@85009,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein gnl|extdb|FAM19036-p1-1.1_000727 1171373.PACID_25080 7.1e-264 916.0 Propionibacteriales nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2GJHB@201174,4DN6W@85009,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration gnl|extdb|FAM19036-p1-1.1_000728 1171373.PACID_25070 1.6e-224 785.0 Propionibacteriales mgtA GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K12583 ko00000,ko01000,ko01003 GT4 Bacteria 2GIZG@201174,4DNSP@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM19036-p1-1.1_000729 1171373.PACID_25060 1.8e-288 998.4 Propionibacteriales deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4DNT3@85009,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase gnl|extdb|FAM19036-p1-1.1_000731 1171373.PACID_25040 4.8e-128 463.8 Propionibacteriales yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 2GMTM@201174,4DQ98@85009,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family gnl|extdb|FAM19036-p1-1.1_000732 1171373.PACID_25030 8.2e-96 356.3 Propionibacteriales rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128,2.3.1.234 ko:K01409,ko:K03789,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03009,ko03016 Bacteria 2HZJR@201174,4DS7Z@85009,COG0454@1,COG0456@2 NA|NA|NA K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 gnl|extdb|FAM19036-p1-1.1_000733 1171373.PACID_25020 1.9e-189 668.3 Propionibacteriales tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GJ98@201174,4DP6P@85009,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction gnl|extdb|FAM19036-p1-1.1_000734 1171373.PACID_25010 1.2e-263 915.2 Propionibacteriales pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 2HCVR@201174,4DWUZ@85009,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family gnl|extdb|FAM19036-p1-1.1_000735 1171373.PACID_25000 8.1e-223 779.2 Bacteria pflA 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 Bacteria COG1180@1,COG1180@2 NA|NA|NA C glycyl-radical enzyme activating activity gnl|extdb|FAM19036-p1-1.1_000736 1171373.PACID_24990 3.4e-111 407.5 Actinobacteria ko:K06990,ko:K09141 ko00000,ko04812 Bacteria 2ISCW@201174,COG2078@1,COG2078@2 NA|NA|NA S AMMECR1 gnl|extdb|FAM19036-p1-1.1_000737 1171373.PACID_24980 1.1e-150 539.3 Bacteria ko:K06990 ko00000,ko04812 Bacteria COG1355@1,COG1355@2 NA|NA|NA C regulation of microtubule-based process gnl|extdb|FAM19036-p1-1.1_000738 1171373.PACID_24970 1.1e-94 352.4 Actinobacteria mutT 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2INEI@201174,COG1051@1,COG1051@2 NA|NA|NA F NTP pyrophosphohydrolases including oxidative damage repair enzymes gnl|extdb|FAM19036-p1-1.1_000739 1171373.PACID_24960 3.5e-219 767.3 Propionibacteriales Bacteria 2GK97@201174,4DPMI@85009,COG2265@1,COG2265@2 NA|NA|NA J COG0500 SAM-dependent methyltransferases gnl|extdb|FAM19036-p1-1.1_000740 1171373.PACID_24950 7.1e-113 413.3 Propionibacteriales Z012_10940 ko:K09807 ko00000 Bacteria 2I888@201174,4DWJD@85009,COG3471@1,COG3471@2 NA|NA|NA S Protein of unknown function (DUF541) gnl|extdb|FAM19036-p1-1.1_000741 1171373.PACID_24940 8.8e-47 192.6 Propionibacteriales groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IKTH@201174,4DR0X@85009,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter gnl|extdb|FAM19036-p1-1.1_000742 1171373.PACID_24930 2.1e-288 997.7 Propionibacteriales groL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2GKC9@201174,4DNCJ@85009,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions gnl|extdb|FAM19036-p1-1.1_000743 1171373.PACID_24920 1.6e-226 792.0 Actinobacteria ko:K14337,ko:K14339 ko00000,ko01000,ko01003 Bacteria 2DBIT@1,2GN03@201174,2Z9GU@2 NA|NA|NA S Carotene biosynthesis associated membrane protein gnl|extdb|FAM19036-p1-1.1_000744 1171373.PACID_24910 2.9e-290 1003.8 Propionibacteriales guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GITZ@201174,4DN68@85009,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth gnl|extdb|FAM19036-p1-1.1_000745 1171373.PACID_24900 2.8e-207 727.6 Propionibacteriales guaB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKVS@201174,4DN1G@85009,COG0516@1,COG0516@2 NA|NA|NA F IMP dehydrogenase / GMP reductase domain gnl|extdb|FAM19036-p1-1.1_000746 1171373.PACID_24880 3.4e-49 200.7 Propionibacteriales tyrA 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQ46@201174,4DRPY@85009,COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase type II gnl|extdb|FAM19036-p1-1.1_000747 1171373.PACID_24870 2.2e-86 325.1 Propionibacteriales cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0840 Bacteria 2IHW5@201174,4DSPI@85009,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) gnl|extdb|FAM19036-p1-1.1_000748 1171373.PACID_24860 5.8e-299 1032.7 Propionibacteriales guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 2GM09@201174,4DPFU@85009,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP gnl|extdb|FAM19036-p1-1.1_000749 1171373.PACID_24850 2e-49 201.4 Propionibacteriales Bacteria 2GWIA@201174,4DSQM@85009,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain gnl|extdb|FAM19036-p1-1.1_000751 1171373.PACID_24830 2.1e-208 731.5 Propionibacteriales Bacteria 2GIVS@201174,4DS1M@85009,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain gnl|extdb|FAM19036-p1-1.1_000752 1171373.PACID_24820 3.1e-243 847.4 Propionibacteriales tcsS3 Bacteria 2GJ4J@201174,4DNII@85009,COG1983@1,COG1983@2,COG4585@1,COG4585@2 NA|NA|NA T PspC domain gnl|extdb|FAM19036-p1-1.1_000753 1171373.PACID_24810 4.9e-117 427.2 Propionibacteriales degU ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2GIVA@201174,4DQ1R@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_000754 1171373.PACID_24800 2.4e-40 171.0 Actinobacteria MA20_40075 Bacteria 2GQR5@201174,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein gnl|extdb|FAM19036-p1-1.1_000757 1171373.PACID_24770 2.3e-190 671.4 Propionibacteriales metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GJ9P@201174,4DPWT@85009,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system gnl|extdb|FAM19036-p1-1.1_000758 1171373.PACID_24760 5.2e-173 613.6 Propionibacteriales metQ_3 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GMNI@201174,4DPJ9@85009,COG1464@1,COG1464@2 NA|NA|NA P NLPA lipoprotein gnl|extdb|FAM19036-p1-1.1_000759 1171373.PACID_24730 0.0 1590.9 Propionibacteriales pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GISS@201174,4DP2M@85009,COG0210@1,COG0210@2 NA|NA|NA L UvrD-like helicase C-terminal domain gnl|extdb|FAM19036-p1-1.1_000760 1171373.PACID_24720 2.1e-173 615.1 Propionibacteriales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GXEC@201174,4DRF9@85009,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 gnl|extdb|FAM19036-p1-1.1_000761 1171373.PACID_24710 3.9e-215 753.8 Propionibacteriales sucC 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKSB@201174,4DN8B@85009,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit gnl|extdb|FAM19036-p1-1.1_000762 1171373.PACID_24700 4.4e-158 563.9 Propionibacteriales sucD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01902,ko:K02381 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK00@201174,4DN33@85009,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit gnl|extdb|FAM19036-p1-1.1_000763 1171373.PACID_24690 5.7e-293 1013.1 Bacteria Bacteria 2CEJR@1,34283@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000764 1171373.PACID_24680 7.5e-115 420.2 Propionibacteriales Bacteria 2I39E@201174,4DX1A@85009,COG3266@1,COG3266@2 NA|NA|NA S domain, Protein gnl|extdb|FAM19036-p1-1.1_000765 1171373.PACID_24670 1.8e-199 701.8 Propionibacteriales ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iLJ478.TM1828,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 Bacteria 2GKAX@201174,4DNKD@85009,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate gnl|extdb|FAM19036-p1-1.1_000766 1171373.PACID_24660 6.9e-113 413.3 Propionibacteriales ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950 Bacteria 2GKC5@201174,4DQ6E@85009,COG0307@1,COG0307@2 NA|NA|NA H riboflavin synthase, alpha gnl|extdb|FAM19036-p1-1.1_000767 1171373.PACID_24650 6e-249 866.3 Propionibacteriales ribA 3.5.4.25,4.1.99.12 ko:K01497,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWJ@201174,4DNA4@85009,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate gnl|extdb|FAM19036-p1-1.1_000768 1171373.PACID_24640 3.3e-83 314.3 Propionibacteriales ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 Bacteria 2II1Z@201174,4DQTS@85009,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin gnl|extdb|FAM19036-p1-1.1_000769 1171373.PACID_24630 3.4e-103 380.9 Propionibacteriales purN GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564 2.1.2.2,2.1.2.3,3.5.4.10 ko:K00602,ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04325,R04326,R04560 RC00026,RC00197,RC00263,RC00456,RC01128 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2H8QB@201174,4DPAW@85009,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate gnl|extdb|FAM19036-p1-1.1_000770 1171373.PACID_24620 2.1e-293 1014.2 Propionibacteriales purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS04230,iJN678.purH Bacteria 2GJWU@201174,4DP1R@85009,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH gnl|extdb|FAM19036-p1-1.1_000771 1171373.PACID_24610 9.7e-169 599.4 Actinobacteria Bacteria 2DXWE@1,2H8B6@201174,346YS@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000772 1171373.PACID_24600 1.3e-159 568.9 Propionibacteriales folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZS@201174,4DNC5@85009,COG0190@1,COG0190@2 NA|NA|NA H Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate gnl|extdb|FAM19036-p1-1.1_000774 1171373.PACID_24580 6.1e-252 876.3 Actinobacteria pduP 1.2.1.87 ko:K13922 ko00640,map00640 R09097 RC00004,RC00184 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2291,iECED1_1282.ECED1_3458 Bacteria 2GJI2@201174,COG1012@1,COG1012@2 NA|NA|NA C Dehydrogenase gnl|extdb|FAM19036-p1-1.1_000775 1171373.PACID_24560 4.2e-178 630.6 Propionibacteriales mdh GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJHS@201174,4DN1I@85009,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate gnl|extdb|FAM19036-p1-1.1_000776 1171373.PACID_24550 9.6e-165 586.3 Propionibacteriales purU 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 2GM0G@201174,4DP82@85009,COG0788@1,COG0788@2 NA|NA|NA F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) gnl|extdb|FAM19036-p1-1.1_000777 1171373.PACID_24540 0.0 1461.0 Propionibacteriales icd 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ1C@201174,4DPVX@85009,COG2838@1,COG2838@2 NA|NA|NA C Isocitrate dehydrogenase gnl|extdb|FAM19036-p1-1.1_000778 1171373.PACID_24530 4.3e-150 537.3 Actinobacteria 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 2GS4Q@201174,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_000779 1171373.PACID_24520 6.1e-244 849.7 Propionibacteriales ytfL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 2GKN5@201174,4DPDV@85009,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain gnl|extdb|FAM19036-p1-1.1_000781 1171373.PACID_24500 5.2e-177 627.1 Propionibacteriales ko:K07335 ko00000 Bacteria 2GMFS@201174,4DP1A@85009,COG1744@1,COG1744@2 NA|NA|NA S ABC transporter substrate-binding protein PnrA-like gnl|extdb|FAM19036-p1-1.1_000782 1171373.PACID_24490 1.3e-298 1031.6 Propionibacteriales rbsA 3.6.3.17 ko:K02056 M00221 ko00000,ko00002,ko01000,ko02000 3.A.1.2 Bacteria 2H7KJ@201174,4DN52@85009,COG3845@1,COG3845@2 NA|NA|NA S ABC transporter, ATP-binding protein gnl|extdb|FAM19036-p1-1.1_000783 1171373.PACID_24480 2.6e-236 824.3 Propionibacteriales ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 2GKAZ@201174,4DNPP@85009,COG4603@1,COG4603@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family gnl|extdb|FAM19036-p1-1.1_000784 1171373.PACID_24470 1.3e-217 762.3 Propionibacteriales ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 2GKMB@201174,4DN21@85009,COG1079@1,COG1079@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family gnl|extdb|FAM19036-p1-1.1_000785 1171373.PACID_24460 1.1e-73 282.3 Propionibacteriales cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 2IHP7@201174,4DRAA@85009,COG0295@1,COG0295@2 NA|NA|NA F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis gnl|extdb|FAM19036-p1-1.1_000786 1171373.PACID_24450 4.4e-188 663.7 Propionibacteriales rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GK53@201174,4DR5Z@85009,COG0328@1,COG0328@2,COG4994@1,COG4994@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids gnl|extdb|FAM19036-p1-1.1_000787 1171373.PACID_24440 0.0 1245.0 Propionibacteriales metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK4S@201174,4DNQ0@85009,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation gnl|extdb|FAM19036-p1-1.1_000788 1171373.PACID_24430 5.5e-110 403.7 Propionibacteriales 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GM18@201174,4DQW6@85009,COG0572@1,COG0572@2 NA|NA|NA F ATP-binding protein gnl|extdb|FAM19036-p1-1.1_000789 1171373.PACID_24420 2.2e-207 728.0 Propionibacteriales 5.1.1.4 ko:K01777 ko00330,ko01100,map00330,map01100 R01255 RC00479 ko00000,ko00001,ko01000 Bacteria 2GM47@201174,4DNIG@85009,COG3938@1,COG3938@2 NA|NA|NA E Proline racemase gnl|extdb|FAM19036-p1-1.1_000790 1171373.PACID_24410 6.2e-89 333.6 Bacteria Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_000791 1171373.PACID_24400 3.1e-138 497.7 Actinobacteria prdB 1.21.4.1,1.21.4.2 ko:K10672,ko:K10794 ko00330,map00330 R02825 RC00790 ko00000,ko00001,ko01000 Bacteria 2GQU6@201174,COG1978@1,COG1978@2 NA|NA|NA S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) gnl|extdb|FAM19036-p1-1.1_000792 1171373.PACID_24390 4.9e-27 126.3 Actinobacteria Bacteria 2D4QX@1,2H7E1@201174,33CC8@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000793 1171373.PACID_24380 0.0 1116.3 Bacteria prdA 1.21.4.1 ko:K10793 ko00330,map00330 R02825 RC00790 ko00000,ko00001,ko01000 Bacteria COG0252@1,COG0252@2,COG5275@1,COG5275@2 NA|NA|NA S DNA clamp loader activity gnl|extdb|FAM19036-p1-1.1_000795 1171373.PACID_24360 2.6e-233 814.3 Propionibacteriales argD 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKE9@201174,4DNMX@85009,COG4992@1,COG4992@2 NA|NA|NA E Aminotransferase class-III gnl|extdb|FAM19036-p1-1.1_000796 1171373.PACID_24340 8.8e-307 1058.9 Propionibacteriales yciQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GNW7@201174,4DS0U@85009,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) gnl|extdb|FAM19036-p1-1.1_000798 1171373.PACID_24310 0.0 1104.7 Propionibacteriales pgcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ3Q@201174,4DMY7@85009,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, C-terminal domain gnl|extdb|FAM19036-p1-1.1_000799 1171373.PACID_24300 4.9e-148 530.4 Propionibacteriales punA GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 2GKEI@201174,4DMXP@85009,COG0005@1,COG0005@2 NA|NA|NA F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate gnl|extdb|FAM19036-p1-1.1_000800 1171373.PACID_24290 3.5e-255 887.1 Propionibacteriales lpdA GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GMP7@201174,4DNPF@85009,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM19036-p1-1.1_000801 1171373.PACID_24280 2.1e-134 485.0 Propionibacteriales Bacteria 2A4ZY@1,2GMC5@201174,30TN1@2,4DP8P@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000802 1171373.PACID_24270 0.0 1163.7 Propionibacteriales accA 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIZP@201174,4DMZN@85009,COG4770@1,COG4770@2 NA|NA|NA I Biotin carboxylase C-terminal domain gnl|extdb|FAM19036-p1-1.1_000803 1171373.PACID_24260 3.9e-87 327.4 Propionibacteriales 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2GURX@201174,4DVQ5@85009,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain gnl|extdb|FAM19036-p1-1.1_000804 1171373.PACID_24250 2.5e-144 518.1 Actinobacteria thiD 2.7.1.35,2.7.1.49,2.7.4.7 ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 M00127 R00174,R01909,R02493,R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKZM@201174,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase gnl|extdb|FAM19036-p1-1.1_000805 1171373.PACID_24240 2.6e-213 747.7 Propionibacteriales Bacteria 2GK0T@201174,4DVC5@85009,COG3214@1,COG3214@2 NA|NA|NA S Winged helix DNA-binding domain gnl|extdb|FAM19036-p1-1.1_000806 1171373.PACID_24230 2.7e-123 448.0 Propionibacteriales Bacteria 2GKK7@201174,4DRYB@85009,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM19036-p1-1.1_000807 1171373.PACID_24220 1.9e-239 834.7 Propionibacteriales arcA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 2GJTR@201174,4DNHZ@85009,COG2235@1,COG2235@2 NA|NA|NA E Amidinotransferase gnl|extdb|FAM19036-p1-1.1_000808 765123.HMPREF9621_02000 1.8e-13 82.4 Bacteria Bacteria COG2235@1,COG2235@2 NA|NA|NA E arginine gnl|extdb|FAM19036-p1-1.1_000809 1171373.PACID_24200 2.2e-119 434.9 Propionibacteriales maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2GNI0@201174,4DQJD@85009,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein gnl|extdb|FAM19036-p1-1.1_000811 1171373.PACID_24180 2.2e-301 1040.8 Propionibacteriales pccB GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494 2.1.3.1,2.1.3.15,6.4.1.3 ko:K01966,ko:K17489 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R00353,R01859 RC00040,RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRU@201174,4DNBQ@85009,COG4799@1,COG4799@2 NA|NA|NA I Carboxyl transferase domain gnl|extdb|FAM19036-p1-1.1_000813 1171373.PACID_24160 1.1e-132 479.2 Propionibacteriales Bacteria 2GZK5@201174,4DR4C@85009,COG3340@1,COG3340@2 NA|NA|NA E Peptidase family S51 gnl|extdb|FAM19036-p1-1.1_000814 1171373.PACID_24150 1.4e-76 292.4 Propionibacteriales Bacteria 2GK6Y@201174,4DRJ7@85009,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain gnl|extdb|FAM19036-p1-1.1_000815 1171373.PACID_24140 1.4e-242 845.1 Propionibacteriales purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 2GJCU@201174,4DPHF@85009,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) gnl|extdb|FAM19036-p1-1.1_000816 1171373.PACID_24130 1.6e-100 372.1 Propionibacteriales purE GO:0008150,GO:0040007 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iJN678.purE,iNJ661.Rv3275c Bacteria 2IFFD@201174,4DQ6R@85009,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) gnl|extdb|FAM19036-p1-1.1_000819 1171373.PACID_24110 1.5e-186 658.7 Propionibacteriales exoA Bacteria 2GMWF@201174,4DQ16@85009,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 21 gnl|extdb|FAM19036-p1-1.1_000820 1171373.PACID_24100 4.4e-62 243.8 Bacteria Bacteria COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase gnl|extdb|FAM19036-p1-1.1_000821 1171373.PACID_24100 3e-36 157.9 Bacteria Bacteria COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase gnl|extdb|FAM19036-p1-1.1_000822 1171373.PACID_24090 1.6e-202 711.8 Propionibacteriales manC 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRM@201174,4DPTJ@85009,COG0836@1,COG0836@2 NA|NA|NA M Nucleotidyl transferase gnl|extdb|FAM19036-p1-1.1_000823 1171373.PACID_24080 3.9e-76 290.8 Bacteria Bacteria 2956M@1,2ZSJ3@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000824 1171373.PACID_24060 5.1e-43 179.9 Propionibacteriales whiB2 ko:K18955 ko00000,ko03000 Bacteria 2CC1Y@1,2IQ4Q@201174,32RUK@2,4DRN7@85009 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA gnl|extdb|FAM19036-p1-1.1_000825 1171373.PACID_24050 0.0 2095.5 Propionibacteriales Bacteria 2GIUN@201174,4DN93@85009,COG1216@1,COG1216@2 NA|NA|NA S PFAM Glycosyl transferase family 2 gnl|extdb|FAM19036-p1-1.1_000826 1032480.MLP_39260 8.3e-18 98.6 Propionibacteriales dedD ko:K02520,ko:K03749,ko:K06204,ko:K16291 ko02026,map02026 ko00000,ko00001,ko01002,ko01011,ko03000,ko03009,ko03012,ko03021,ko03029 Bacteria 2HC8A@201174,4DRQT@85009,COG3147@1,COG3147@2 NA|NA|NA S Non-essential cell division protein that could be required for efficient cell constriction gnl|extdb|FAM19036-p1-1.1_000827 1171373.PACID_24030 9.7e-60 236.1 Propionibacteriales MA20_43655 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2GR5W@201174,4DS4T@85009,COG3824@1,COG3824@2 NA|NA|NA S Zincin-like metallopeptidase gnl|extdb|FAM19036-p1-1.1_000828 1171373.PACID_24020 2.8e-69 267.7 Propionibacteriales Bacteria 2C7XW@1,2IQ5R@201174,32RR4@2,4DRSS@85009 NA|NA|NA S Protein of unknown function (DUF3499) gnl|extdb|FAM19036-p1-1.1_000829 1171373.PACID_24010 1.2e-35 155.2 Propionibacteriales ycaR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 ko:K00912,ko:K09791 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2HUT7@201174,4DSPV@85009,COG2835@1,COG2835@2 NA|NA|NA S Trm112p-like protein gnl|extdb|FAM19036-p1-1.1_000830 1171373.PACID_24000 1.2e-191 675.6 Propionibacteriales 5.3.1.8,5.3.1.9 ko:K15916 ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R01819,R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMG0@201174,4DMZS@85009,COG1737@1,COG1737@2 NA|NA|NA K Bacterial phospho-glucose isomerase C-terminal SIS domain gnl|extdb|FAM19036-p1-1.1_000831 1171373.PACID_23990 1e-165 589.3 Propionibacteriales cat Bacteria 2GKSG@201174,4DPUX@85009,COG0053@1,COG0053@2 NA|NA|NA P Cation efflux family gnl|extdb|FAM19036-p1-1.1_000832 1171373.PACID_23980 2.9e-90 337.8 Propionibacteriales aroQ 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 iIT341.HP1038 Bacteria 2INEE@201174,4DWR0@85009,COG0757@1,COG0757@2 NA|NA|NA E Catalyzes a trans-dehydration via an enolate intermediate gnl|extdb|FAM19036-p1-1.1_000833 1171373.PACID_23970 3.2e-42 177.2 Bacteria Bacteria 2CAFG@1,32ZDZ@2 NA|NA|NA S Protein of unknown function (DUF3039) gnl|extdb|FAM19036-p1-1.1_000835 1171373.PACID_23940 0.0 1461.4 Propionibacteriales malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 ko:K00700,ko:K00705,ko:K02438,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R02110,R02111,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13,GH77 iJN678.malQ Bacteria 2GM5Z@201174,4DPPR@85009,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase gnl|extdb|FAM19036-p1-1.1_000836 1171373.PACID_23930 1.4e-38 165.2 Propionibacteriales hup GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 2IKQR@201174,4DSEF@85009,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family gnl|extdb|FAM19036-p1-1.1_000837 1171373.PACID_23920 1.6e-249 868.2 Propionibacteriales pncB 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 2GJAT@201174,4DN3A@85009,COG1488@1,COG1488@2 NA|NA|NA H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP gnl|extdb|FAM19036-p1-1.1_000838 1171373.PACID_23910 1.3e-51 208.8 Actinobacteria clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 ko:K06891 ko00000 Bacteria 2IQ3Z@201174,COG2127@1,COG2127@2 NA|NA|NA S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation gnl|extdb|FAM19036-p1-1.1_000839 1120954.ATXE01000003_gene572 1.7e-23 116.3 Bacteria Bacteria 2E4AX@1,32Z6K@2 NA|NA|NA S Domain of unknown function (DUF2017) gnl|extdb|FAM19036-p1-1.1_000842 1120954.ATXE01000003_gene575 1.4e-21 109.0 Actinobacteria Bacteria 2DSIG@1,2H0P5@201174,33G9P@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000843 1171373.PACID_23860 4.8e-162 577.0 Propionibacteriales murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0042802,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 2GN4I@201174,4DP8J@85009,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis gnl|extdb|FAM19036-p1-1.1_000845 1171373.PACID_23840 9.8e-112 409.5 Propionibacteriales rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2GM2B@201174,4DQ0I@85009,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions gnl|extdb|FAM19036-p1-1.1_000846 1171373.PACID_23830 7.8e-162 576.2 Propionibacteriales thyA 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKY0@201174,4DPMT@85009,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis gnl|extdb|FAM19036-p1-1.1_000848 1171373.PACID_23810 4.7e-263 913.3 Propionibacteriales dinB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 2GKBI@201174,4DN0X@85009,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII gnl|extdb|FAM19036-p1-1.1_000849 1171373.PACID_23800 2.4e-109 401.4 Propionibacteriales Bacteria 2GW5J@201174,4DRV2@85009,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain gnl|extdb|FAM19036-p1-1.1_000851 1171373.PACID_23780 1.2e-85 322.4 Propionibacteriales bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 ko00000,ko01000 iPC815.YPO3064 Bacteria 2IHZ6@201174,4DQGR@85009,COG1225@1,COG1225@2 NA|NA|NA O Redoxin gnl|extdb|FAM19036-p1-1.1_000852 1171373.PACID_23770 3.7e-92 344.4 Bacteria Bacteria 296K5@1,2ZTVJ@2 NA|NA|NA S Protein of unknown function (DUF3618) gnl|extdb|FAM19036-p1-1.1_000857 1171373.PACID_23730 4.2e-135 487.3 Propionibacteriales cobQ ko:K07009 ko00000 iSB619.SA_RS09800 Bacteria 2GKPV@201174,4DUT1@85009,COG3442@1,COG3442@2 NA|NA|NA S CobB/CobQ-like glutamine amidotransferase domain gnl|extdb|FAM19036-p1-1.1_000858 1171373.PACID_23720 1.8e-240 838.2 Propionibacteriales murE 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2I2TV@201174,4DU2N@85009,COG0769@1,COG0769@2 NA|NA|NA M Domain of unknown function (DUF1727) gnl|extdb|FAM19036-p1-1.1_000860 1171373.PACID_23690 1.1e-294 1018.5 Propionibacteriales dinB_2 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 2GMZ3@201174,4DNV5@85009,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family gnl|extdb|FAM19036-p1-1.1_000861 1171373.PACID_23680 0.0 2268.4 Propionibacteriales dnaE2 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 ko:K00960,ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ1P@201174,4DNZC@85009,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase gnl|extdb|FAM19036-p1-1.1_000862 1171373.PACID_23670 1.5e-79 302.0 Bacteria phnB2 ko:K04750 ko00000 Bacteria COG2764@1,COG2764@2 NA|NA|NA E glyoxalase bleomycin resistance protein dioxygenase gnl|extdb|FAM19036-p1-1.1_000863 1171373.PACID_23660 0.0 1101.7 Propionibacteriales ko:K03294 ko00000 2.A.3.2 Bacteria 2GJ75@201174,4DN3R@85009,COG0531@1,COG0531@2 NA|NA|NA E C-terminus of AA_permease gnl|extdb|FAM19036-p1-1.1_000864 1171373.PACID_23650 0.0 1568.9 Propionibacteriales uvrA2 Bacteria 2GJUV@201174,4DN67@85009,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter gnl|extdb|FAM19036-p1-1.1_000866 1171373.PACID_03220 2.5e-247 860.9 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_000869 1171373.PACID_23620 4.1e-80 303.9 Actinobacteria gloA 3.2.2.1 ko:K01239,ko:K08234 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 2IFKS@201174,COG0346@1,COG0346@2 NA|NA|NA E glyoxalase bleomycin resistance protein dioxygenase gnl|extdb|FAM19036-p1-1.1_000870 1171373.PACID_23610 2.8e-82 311.2 Propionibacteriales Bacteria 2HR2U@201174,4DVRJ@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM19036-p1-1.1_000871 1171373.PACID_23600 5.7e-155 553.5 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,4DTG1@85009,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM19036-p1-1.1_000872 1171373.PACID_23590 1.6e-112 412.1 Actinobacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJGH@201174,COG0842@1,COG0842@2 NA|NA|NA V transport, permease protein gnl|extdb|FAM19036-p1-1.1_000873 1171373.PACID_23580 1.5e-91 342.0 Propionibacteriales tdsD Bacteria 2IHY1@201174,4DVVQ@85009,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family gnl|extdb|FAM19036-p1-1.1_000874 1171373.PACID_23570 1.6e-267 928.3 Actinobacteria cycA ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 Bacteria 2GJ0X@201174,COG1113@1,COG1113@2 NA|NA|NA E amino acid gnl|extdb|FAM19036-p1-1.1_000875 1171373.PACID_23560 2.4e-112 411.4 Bacteria Bacteria 2ENA9@1,33FXZ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000876 1171373.PACID_23550 1.4e-119 435.6 Actinobacteria hrtA ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GNB3@201174,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter gnl|extdb|FAM19036-p1-1.1_000877 1171373.PACID_23540 1.3e-180 639.0 Actinobacteria hrtB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02004,ko:K09813 ko02010,map02010 M00257,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1 Bacteria 2GMC4@201174,COG0577@1,COG0577@2 NA|NA|NA V ABC-type antimicrobial peptide transport system, permease component gnl|extdb|FAM19036-p1-1.1_000879 1171373.PACID_23520 3.6e-103 380.9 Propionibacteriales hrrA Bacteria 2GJRY@201174,4DQ5B@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_000880 1171373.PACID_23510 1e-104 386.0 Propionibacteriales pcm 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 2GJ3I@201174,4DR4F@85009,COG2518@1,COG2518@2 NA|NA|NA O Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) gnl|extdb|FAM19036-p1-1.1_000881 1171373.PACID_23500 8.5e-44 182.6 Bacteria Bacteria 2C3CF@1,32RRR@2 NA|NA|NA S Protein of unknown function (DUF3175) gnl|extdb|FAM19036-p1-1.1_000882 1171373.PACID_23370 0.0 1306.6 Actinobacteria Bacteria 2IBDU@201174,COG0553@1,COG0553@2 NA|NA|NA L helicase gnl|extdb|FAM19036-p1-1.1_000883 1171373.PACID_23350 4.3e-144 517.3 Propionibacteriales Bacteria 2GJS3@201174,4DPQ7@85009,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM19036-p1-1.1_000886 1171373.PACID_23320 1.6e-123 448.7 Propionibacteriales 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 2H7J9@201174,4DQ6W@85009,COG1794@1,COG1794@2 NA|NA|NA M Asp/Glu/Hydantoin racemase gnl|extdb|FAM19036-p1-1.1_000888 436229.JOEH01000026_gene2454 3.9e-57 227.6 Streptacidiphilus yjhE Bacteria 2C3KP@1,2IFTZ@201174,2NI3W@228398,2Z802@2 NA|NA|NA S phage tail protein gnl|extdb|FAM19036-p1-1.1_000889 1171373.PACID_23290 2.2e-124 451.8 Propionibacteriales tam GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0030798,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 2.1.1.144,2.1.1.197 ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c17460,iSDY_1059.SDY_1625,ic_1306.c1942 Bacteria 2GJMG@201174,4DP5H@85009,COG4106@1,COG4106@2 NA|NA|NA S Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate gnl|extdb|FAM19036-p1-1.1_000893 1171373.PACID_23250 4.1e-245 853.6 Actinobacteria Bacteria 2GKR5@201174,COG2339@1,COG2339@2 NA|NA|NA NU membrane gnl|extdb|FAM19036-p1-1.1_000894 1171373.PACID_23240 7.3e-81 306.6 Propionibacteriales ssb2 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GQIQ@201174,4DS96@85009,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein gnl|extdb|FAM19036-p1-1.1_000895 1171373.PACID_23230 0.0 1127.1 Propionibacteriales yjjK GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 2GKBQ@201174,4DNB9@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM19036-p1-1.1_000896 1171373.PACID_23220 0.0 1914.4 Propionibacteriales Bacteria 2GKI9@201174,4DN5D@85009,COG0247@1,COG0247@2,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain gnl|extdb|FAM19036-p1-1.1_000897 1171373.PACID_23210 1.4e-81 308.9 Propionibacteriales Bacteria 2GP6A@201174,4DR7Q@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM19036-p1-1.1_000898 1171373.PACID_23200 0.0 1244.2 Propionibacteriales fadD11_1 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4DNTY@85009,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme gnl|extdb|FAM19036-p1-1.1_000899 1171373.PACID_23190 0.0 1247.3 Propionibacteriales fadD11_1 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4DNTY@85009,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme gnl|extdb|FAM19036-p1-1.1_000900 1171373.PACID_23180 1.1e-164 585.9 Propionibacteriales ko:K07107 ko00000,ko01000 Bacteria 2IFAK@201174,4DRTF@85009,COG0824@1,COG0824@2 NA|NA|NA S Acyl-ACP thioesterase gnl|extdb|FAM19036-p1-1.1_000902 1171373.PACID_23160 3e-218 764.2 Propionibacteriales yfmO ko:K08221 ko00000,ko02000 2.A.1.32 Bacteria 2GK1K@201174,4DMYY@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000903 1171373.PACID_23150 9.9e-94 349.4 Propionibacteriales 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 2II7F@201174,4DRQV@85009,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_000904 1171373.PACID_23140 4.6e-274 949.9 Propionibacteriales gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 2GJ2J@201174,4DQ33@85009,COG0362@1,COG0362@2 NA|NA|NA G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnl|extdb|FAM19036-p1-1.1_000906 1171373.PACID_23120 0.0 1731.5 Propionibacteriales pepN 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ4@201174,4DNEA@85009,COG0308@1,COG0308@2 NA|NA|NA E ERAP1-like C-terminal domain gnl|extdb|FAM19036-p1-1.1_000908 1171373.PACID_23100 0.0 1464.1 Propionibacteriales ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJUY@201174,4DNKM@85009,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA gnl|extdb|FAM19036-p1-1.1_000909 1171373.PACID_23090 9.3e-112 409.5 Actinobacteria Bacteria 2I90W@201174,COG1670@1,COG1670@2 NA|NA|NA J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins gnl|extdb|FAM19036-p1-1.1_000910 1171373.PACID_23080 4.3e-247 860.1 Actinobacteria Bacteria 2GNXZ@201174,COG4552@1,COG4552@2 NA|NA|NA S N-acetyltransferase gnl|extdb|FAM19036-p1-1.1_000911 1171373.PACID_23070 8.9e-86 322.8 Propionibacteriales rpiB GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005576,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2465c Bacteria 2GKJG@201174,4DQHW@85009,COG0698@1,COG0698@2 NA|NA|NA G Ribose 5-phosphate isomerase gnl|extdb|FAM19036-p1-1.1_000913 1171373.PACID_23050 7.3e-160 569.7 Propionibacteriales nei1 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K05522,ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKUI@201174,4DN81@85009,COG0266@1,COG0266@2 NA|NA|NA L Belongs to the FPG family gnl|extdb|FAM19036-p1-1.1_000916 1171373.PACID_23020 9.7e-144 516.2 Propionibacteriales Bacteria 2I2NQ@201174,4DW4Z@85009,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family gnl|extdb|FAM19036-p1-1.1_000919 1171373.PACID_22800 6.8e-238 829.7 Propionibacteriales tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K03545 ko00000 Bacteria 2GJIG@201174,4DP8U@85009,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase gnl|extdb|FAM19036-p1-1.1_000920 1171373.PACID_22790 4e-225 787.3 Propionibacteriales tqsA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944 ko:K11744 ko00000 Bacteria 2GM01@201174,4DT6M@85009,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter gnl|extdb|FAM19036-p1-1.1_000921 1171373.PACID_22780 6.2e-108 396.7 Propionibacteriales clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK5C@201174,4DNFI@85009,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins gnl|extdb|FAM19036-p1-1.1_000922 1171373.PACID_22770 1.3e-120 439.1 Propionibacteriales clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKNK@201174,4DNRI@85009,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins gnl|extdb|FAM19036-p1-1.1_000923 1171373.PACID_22760 2.4e-242 844.3 Propionibacteriales clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2GJXQ@201174,4DP0T@85009,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP gnl|extdb|FAM19036-p1-1.1_000925 1171373.PACID_22740 0.0 2161.7 Propionibacteriales tri1 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08676 ko00000,ko01000,ko01002 Bacteria 2GJKW@201174,4DU16@85009,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog gnl|extdb|FAM19036-p1-1.1_000926 1171373.PACID_22730 4.1e-109 400.6 Propionibacteriales Bacteria 2I1DJ@201174,4DR02@85009,COG2318@1,COG2318@2 NA|NA|NA S Protein of unknown function (DUF664) gnl|extdb|FAM19036-p1-1.1_000927 1171373.PACID_22720 4.1e-101 374.0 Actinobacteria adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IJ2R@201174,COG0563@1,COG0563@2 NA|NA|NA F adenylate kinase activity gnl|extdb|FAM19036-p1-1.1_000928 1171373.PACID_22710 0.0 1789.2 Propionibacteriales valS 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK8H@201174,4DNR2@85009,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner gnl|extdb|FAM19036-p1-1.1_000929 1171373.PACID_22700 7.9e-127 459.9 Propionibacteriales pknE_1 Bacteria 2GKH8@201174,4DSCN@85009,COG1651@1,COG1651@2 NA|NA|NA O Thioredoxin gnl|extdb|FAM19036-p1-1.1_000930 1171373.PACID_22690 7.5e-140 503.1 Propionibacteriales pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31,3.5.99.6 ko:K01057,ko:K02003,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008,M00258 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 Bacteria 2GMQ2@201174,4DQAQ@85009,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase gnl|extdb|FAM19036-p1-1.1_000931 1171373.PACID_22680 2.2e-185 654.8 Propionibacteriales opcA Bacteria 2GJ1H@201174,4DP29@85009,COG3429@1,COG3429@2 NA|NA|NA G Glucose-6-phosphate dehydrogenase subunit gnl|extdb|FAM19036-p1-1.1_000933 1171373.PACID_22660 3.7e-182 644.0 Propionibacteriales ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Bacteria 2GJMY@201174,4DN8H@85009,COG0109@1,COG0109@2 NA|NA|NA O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group gnl|extdb|FAM19036-p1-1.1_000935 1171373.PACID_22640 3.5e-132 477.6 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GN6S@201174,4DQ7H@85009,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein gnl|extdb|FAM19036-p1-1.1_000937 1171373.PACID_22620 0.0 1537.3 Propionibacteriales hppA 3.6.1.1 ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 3.A.10.1 Bacteria 2GN8B@201174,4DPFE@85009,COG3808@1,COG3808@2 NA|NA|NA C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force gnl|extdb|FAM19036-p1-1.1_000938 1122998.AUHZ01000004_gene1187 1.6e-177 628.6 Propionibacteriales malR Bacteria 2GJRG@201174,4DNR0@85009,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain gnl|extdb|FAM19036-p1-1.1_000939 1171373.PACID_22570 1.7e-162 578.6 Actinobacteria malG GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 ko:K10110,ko:K15772 ko02010,map02010 M00194,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22 iLJ478.TM1202,iSSON_1240.SSON_4210,iYL1228.KPN_04421 Bacteria 2I2EZ@201174,COG3833@1,COG3833@2 NA|NA|NA P PFAM binding-protein-dependent transport systems inner membrane component gnl|extdb|FAM19036-p1-1.1_000940 1122998.AUHZ01000004_gene1189 1.2e-299 1035.0 Actinobacteria malF GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 ko:K10109,ko:K15771 ko02010,map02010 M00194,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22 iZ_1308.Z5631 Bacteria 2GJGB@201174,COG1175@1,COG1175@2 NA|NA|NA G PFAM binding-protein-dependent transport systems inner membrane component gnl|extdb|FAM19036-p1-1.1_000941 1171373.PACID_22540 1.1e-218 765.8 Bacteria ko:K02027,ko:K15770 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria COG2182@1,COG2182@2 NA|NA|NA G maltose binding gnl|extdb|FAM19036-p1-1.1_000942 1171373.PACID_22520 1.8e-137 495.4 Propionibacteriales sufR Bacteria 2GN8W@201174,4DQCB@85009,COG2345@1,COG2345@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_000945 1171373.PACID_22490 1e-59 235.7 Actinobacteria hcaC 1.7.1.15 ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 2IQK7@201174,COG2146@1,COG2146@2 NA|NA|NA P Rieske 2Fe-2S gnl|extdb|FAM19036-p1-1.1_000946 1171373.PACID_22480 4.6e-140 503.8 Propionibacteriales sufC ko:K09013 ko00000,ko02000 Bacteria 2GKB7@201174,4DNC0@85009,COG0396@1,COG0396@2 NA|NA|NA O assembly ATPase gnl|extdb|FAM19036-p1-1.1_000947 1171373.PACID_22470 7e-242 842.8 Propionibacteriales sufS 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 2GIVK@201174,4DNCW@85009,COG0520@1,COG0520@2 NA|NA|NA E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family gnl|extdb|FAM19036-p1-1.1_000948 1171373.PACID_22460 7.8e-85 319.7 Propionibacteriales iscU ko:K04488 ko00000 Bacteria 2IHY9@201174,4DQS7@85009,COG0822@1,COG0822@2 NA|NA|NA C NifU-like N terminal domain gnl|extdb|FAM19036-p1-1.1_000951 1171373.PACID_22420 4.1e-237 827.0 Actinobacteria GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 2IRY0@201174,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease gnl|extdb|FAM19036-p1-1.1_000952 1171373.PACID_22410 7.1e-145 520.0 Propionibacteriales ypfJ ko:K07054 ko00000 Bacteria 2H3UT@201174,4DQBN@85009,COG2321@1,COG2321@2 NA|NA|NA S Putative neutral zinc metallopeptidase gnl|extdb|FAM19036-p1-1.1_000953 1157632.AQWQ01000014_gene3521 6.4e-47 194.1 Actinobacteria maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 2GNUB@201174,COG0110@1,COG0110@2 NA|NA|NA M Acetyltransferase (isoleucine patch gnl|extdb|FAM19036-p1-1.1_000956 1171373.PACID_22370 1.6e-296 1024.6 Propionibacteriales ybiT Bacteria 2GKQ4@201174,4DPPB@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM19036-p1-1.1_000957 1170318.PALO_03290 1.3e-12 79.7 Bacteria Bacteria 2E4I7@1,32ZDA@2 NA|NA|NA S Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_000959 1171373.PACID_22340 3.6e-129 467.6 Propionibacteriales Bacteria 2GMEH@201174,4DNZG@85009,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM19036-p1-1.1_000962 1171373.PACID_22310 2.1e-118 431.8 Propionibacteriales Bacteria 2GK6C@201174,4DPI8@85009,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM19036-p1-1.1_000963 1171373.PACID_22300 1e-142 512.7 Propionibacteriales inhA GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208,ko:K11611 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJ65@201174,4DNM7@85009,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH gnl|extdb|FAM19036-p1-1.1_000964 1171373.PACID_22290 8.9e-124 449.5 Actinobacteria Bacteria 2I2JR@201174,COG2334@1,COG2334@2 NA|NA|NA S Aminoglycoside phosphotransferase gnl|extdb|FAM19036-p1-1.1_000965 1171373.PACID_22280 6.5e-268 929.5 Propionibacteriales aspA 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 Bacteria 2I2HG@201174,4DPWH@85009,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus gnl|extdb|FAM19036-p1-1.1_000967 1171373.PACID_22270 5.4e-195 686.8 Propionibacteriales dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 2GIRV@201174,4DND1@85009,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) gnl|extdb|FAM19036-p1-1.1_000968 1171373.PACID_22250 1.8e-142 511.9 Propionibacteriales modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028,ko:K05776 ko02010,map02010 M00189,M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 2GIXX@201174,4DNDT@85009,COG1119@1,COG1119@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_000969 1171373.PACID_22240 6.7e-84 316.6 Propionibacteriales nfeD ko:K07340 ko00000 Bacteria 2IHZU@201174,4DRK6@85009,COG1585@1,COG1585@2 NA|NA|NA OU NfeD-like C-terminal, partner-binding gnl|extdb|FAM19036-p1-1.1_000971 1171373.PACID_22220 2.1e-177 628.2 Propionibacteriales ko:K03453,ko:K14347 ko00000,ko02000,ko04147 2.A.28,2.A.93.1 Bacteria 2GJQU@201174,4DT11@85009,COG0385@1,COG0385@2 NA|NA|NA S SBF-like CPA transporter family (DUF4137) gnl|extdb|FAM19036-p1-1.1_000972 1171373.PACID_22210 3.5e-146 524.2 Propionibacteriales spoU2 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ12@201174,4DN3T@85009,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family gnl|extdb|FAM19036-p1-1.1_000973 1121939.L861_22815 5.6e-10 70.9 Oceanospirillales 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 1N458@1224,1RNYG@1236,1XJ2D@135619,COG3550@1,COG3550@2 NA|NA|NA S HipA-like C-terminal domain gnl|extdb|FAM19036-p1-1.1_000974 1171373.PACID_22180 8.1e-45 186.0 Propionibacteriales Bacteria 2GR1C@201174,4DVV0@85009,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM19036-p1-1.1_000975 1171373.PACID_22170 1.9e-120 438.3 Propionibacteriales def 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2GJ87@201174,4DQAV@85009,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions gnl|extdb|FAM19036-p1-1.1_000976 1171373.PACID_22160 3.4e-202 710.7 Bacteria 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria COG2706@1,COG2706@2 NA|NA|NA G 6-phosphogluconolactonase activity gnl|extdb|FAM19036-p1-1.1_000977 1171373.PACID_22150 2.9e-176 624.4 Propionibacteriales xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4DN7T@85009,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family. XerC subfamily gnl|extdb|FAM19036-p1-1.1_000978 1171373.PACID_22140 3.7e-190 670.6 Propionibacteriales Bacteria 2IQ64@201174,4DRV5@85009,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 gnl|extdb|FAM19036-p1-1.1_000979 1171373.PACID_22130 0.0 1095.1 Actinobacteria CP_1020 Bacteria 2GNAG@201174,COG4715@1,COG4715@2 NA|NA|NA S Zinc finger, swim domain protein gnl|extdb|FAM19036-p1-1.1_000980 1171373.PACID_22120 1e-171 609.4 Propionibacteriales Bacteria 2GK1P@201174,4DPS2@85009,COG2425@1,COG2425@2 NA|NA|NA S VWA domain containing CoxE-like protein gnl|extdb|FAM19036-p1-1.1_000982 1171373.PACID_22100 3.4e-192 677.6 Propionibacteriales yehL Bacteria 2GMBP@201174,4DPAU@85009,COG0714@1,COG0714@2 NA|NA|NA S AAA domain (dynein-related subfamily) gnl|extdb|FAM19036-p1-1.1_000983 369723.Strop_2883 2.2e-54 219.2 Micromonosporales JD73_20480 Bacteria 2HIEQ@201174,4D9WJ@85008,COG3831@1,COG3831@2 NA|NA|NA S Domain of unknown function (DUF4132) gnl|extdb|FAM19036-p1-1.1_000984 1136417.AZWE01000024_gene705 4.7e-119 435.6 Micromonosporales JD73_20480 Bacteria 2HIEQ@201174,4D9WJ@85008,COG3831@1,COG3831@2 NA|NA|NA S Domain of unknown function (DUF4132) gnl|extdb|FAM19036-p1-1.1_000985 1171373.PACID_22070 1.9e-140 505.4 Propionibacteriales rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMYC@201174,4DP30@85009,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family gnl|extdb|FAM19036-p1-1.1_000986 1171373.PACID_22060 6.4e-140 503.4 Propionibacteriales tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02357 ko00000,ko03012,ko03029 Bacteria 2GK4M@201174,4DNDW@85009,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome gnl|extdb|FAM19036-p1-1.1_000987 1171373.PACID_22050 8.1e-131 473.0 Propionibacteriales pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2GKWQ@201174,4DNEC@85009,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP gnl|extdb|FAM19036-p1-1.1_000988 1171373.PACID_22040 2.4e-90 338.2 Propionibacteriales frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2GJ9J@201174,4DNKY@85009,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another gnl|extdb|FAM19036-p1-1.1_000989 1171373.PACID_22030 1.4e-153 548.9 Propionibacteriales cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNWK@201174,4DQ6M@85009,COG4589@1,COG4589@2 NA|NA|NA S Belongs to the CDS family gnl|extdb|FAM19036-p1-1.1_000990 1171373.PACID_22020 3.9e-234 817.0 Propionibacteriales rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2GJ48@201174,4DPW3@85009,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs gnl|extdb|FAM19036-p1-1.1_000991 1171373.PACID_22010 8.9e-256 889.0 Propionibacteriales gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKXG@201174,4DP86@85009,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family gnl|extdb|FAM19036-p1-1.1_000992 1171373.PACID_22000 4.8e-273 946.4 Propionibacteriales Bacteria 2GK3A@201174,4DQ5N@85009,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM19036-p1-1.1_000993 1171373.PACID_21990 4.1e-234 817.0 Propionibacteriales rseP ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJT@201174,4DPDA@85009,COG0750@1,COG0750@2 NA|NA|NA M Peptidase family M50 gnl|extdb|FAM19036-p1-1.1_000994 1171373.PACID_21980 6.7e-212 743.0 Propionibacteriales ispG GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS06430,iJN678.gcpE Bacteria 2GK2S@201174,4DP7G@85009,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate gnl|extdb|FAM19036-p1-1.1_000995 1171373.PACID_21970 1.2e-162 578.9 Propionibacteriales ko:K06976 ko00000 Bacteria 2GMD2@201174,4DP1G@85009,COG3393@1,COG3393@2 NA|NA|NA S Domain of unknown function (DUF4081) gnl|extdb|FAM19036-p1-1.1_000997 1171373.PACID_21950 0.0 1343.9 Propionibacteriales cotA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.10.3.4,1.16.3.3,1.7.2.1 ko:K00368,ko:K06324,ko:K20219 ko00380,ko00910,ko01120,map00380,map00910,map01120 M00529 R00074,R00783,R00785 RC00086,RC00767,RC02319 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJ4@201174,4DPUK@85009,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase gnl|extdb|FAM19036-p1-1.1_000998 1171373.PACID_21940 1.1e-310 1071.6 Propionibacteriales gcs2 Bacteria 2GN0J@201174,4DPFA@85009,COG2308@1,COG2308@2 NA|NA|NA S Circularly permuted ATP-grasp type 2 gnl|extdb|FAM19036-p1-1.1_000999 1171373.PACID_21930 3.5e-163 580.9 Propionibacteriales MA20_32425 Bacteria 2GN0T@201174,4DP16@85009,COG2307@1,COG2307@2 NA|NA|NA S A predicted alpha-helical domain with a conserved ER motif. gnl|extdb|FAM19036-p1-1.1_001000 1171373.PACID_21920 1.1e-163 582.4 Propionibacteriales Bacteria 2GN5D@201174,4DQH4@85009,COG1305@1,COG1305@2 NA|NA|NA E Bacterial transglutaminase-like N-terminal region gnl|extdb|FAM19036-p1-1.1_001002 1171373.PACID_21900 0.0 1161.7 Propionibacteriales proS GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9G@201174,4DN8W@85009,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS gnl|extdb|FAM19036-p1-1.1_001003 1171373.PACID_21890 2.2e-93 348.2 Propionibacteriales Bacteria 2GNZF@201174,4DRUE@85009,COG5516@1,COG5516@2 NA|NA|NA S CGNR zinc finger gnl|extdb|FAM19036-p1-1.1_001006 1171373.PACID_21860 9.2e-84 316.2 Actinobacteria rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 2I9BT@201174,COG0779@1,COG0779@2 NA|NA|NA S Required for maturation of 30S ribosomal subunits gnl|extdb|FAM19036-p1-1.1_001007 1171373.PACID_21850 2.2e-179 634.8 Propionibacteriales nusA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 2GJDJ@201174,4DN47@85009,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination gnl|extdb|FAM19036-p1-1.1_001008 1171373.PACID_21840 5.3e-43 179.9 Bacteria ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria COG2740@1,COG2740@2 NA|NA|NA K Nucleic-acid-binding protein implicated in transcription termination gnl|extdb|FAM19036-p1-1.1_001009 1171373.PACID_21830 0.0 1220.3 Propionibacteriales infB ko:K02519 ko00000,ko03012,ko03029 Bacteria 2GKPH@201174,4DN57@85009,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gnl|extdb|FAM19036-p1-1.1_001010 1171373.PACID_21820 0.0 1225.7 Propionibacteriales ubiB ko:K03688 ko00000 Bacteria 2GJQ6@201174,4DQX3@85009,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family gnl|extdb|FAM19036-p1-1.1_001012 1171373.PACID_21800 6.2e-260 902.9 Bacteria egsA 1.1.1.261 ko:K00096 ko00564,map00564 R05679,R05680 RC00029 ko00000,ko00001,ko01000 Bacteria COG0371@1,COG0371@2 NA|NA|NA C Dehydrogenase gnl|extdb|FAM19036-p1-1.1_001013 1171373.PACID_21790 2.6e-43 181.0 Bacteria ptsH ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria COG1925@1,COG1925@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system gnl|extdb|FAM19036-p1-1.1_001014 1171373.PACID_21780 8.6e-60 236.1 Actinobacteria srlB 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 Bacteria 2GZXY@201174,COG3731@1,COG3731@2 NA|NA|NA G PTS system glucitol/sorbitol-specific IIA component gnl|extdb|FAM19036-p1-1.1_001016 1171373.PACID_21760 3.3e-106 391.0 Actinobacteria srlA GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 iSBO_1134.SBO_2816 Bacteria 2GJ0C@201174,COG3730@1,COG3730@2 NA|NA|NA G PTS system enzyme II sorbitol-specific factor gnl|extdb|FAM19036-p1-1.1_001017 1171373.PACID_21750 8.1e-85 319.7 Actinobacteria gutM GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02466 ko00000 Bacteria 2HBG3@201174,COG4578@1,COG4578@2 NA|NA|NA K Glucitol operon activator protein (GutM) gnl|extdb|FAM19036-p1-1.1_001018 1171373.PACID_21740 0.0 1229.2 Actinobacteria srlR2 2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K03491 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279 R03232,R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1 Bacteria 2H2QN@201174,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA GKT PRD domain gnl|extdb|FAM19036-p1-1.1_001019 1171373.PACID_21730 2.7e-139 501.5 Propionibacteriales truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 2GJZK@201174,4DPKY@85009,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs gnl|extdb|FAM19036-p1-1.1_001020 1171373.PACID_21720 2.8e-35 154.1 Actinobacteria Bacteria 2GXCS@201174,COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 gnl|extdb|FAM19036-p1-1.1_001021 1171373.PACID_21710 3.8e-67 260.8 Bacteria ko:K07075 ko00000 Bacteria COG1669@1,COG1669@2 NA|NA|NA S nucleotidyltransferase activity gnl|extdb|FAM19036-p1-1.1_001022 1171373.PACID_21700 1.4e-175 622.1 Propionibacteriales ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQF@201174,4DNXK@85009,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family gnl|extdb|FAM19036-p1-1.1_001023 1171373.PACID_21690 2.2e-41 174.5 Propionibacteriales rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQA0@201174,4DS16@85009,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome gnl|extdb|FAM19036-p1-1.1_001024 1171373.PACID_02680 2.2e-229 801.2 Actinobacteria Bacteria 2I8Z0@201174,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives gnl|extdb|FAM19036-p1-1.1_001025 1171373.PACID_21680 0.0 1409.0 Propionibacteriales pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2GIT2@201174,4DP91@85009,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction gnl|extdb|FAM19036-p1-1.1_001026 1171373.PACID_21670 5.6e-135 486.9 Propionibacteriales dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iYO844.BSU22490 Bacteria 2GM2T@201174,4DNG2@85009,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate gnl|extdb|FAM19036-p1-1.1_001027 1171373.PACID_21660 1.2e-109 402.9 Bacteria Bacteria 2DR5D@1,33A8R@2 NA|NA|NA S Protein of unknown function (DUF2993) gnl|extdb|FAM19036-p1-1.1_001028 1171373.PACID_21650 0.0 1143.6 Propionibacteriales poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 2GJ20@201174,4DQ50@85009,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM19036-p1-1.1_001029 1171373.PACID_21640 8.3e-105 386.3 Propionibacteriales Bacteria 2I2XB@201174,4DQWV@85009,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family gnl|extdb|FAM19036-p1-1.1_001030 1171373.PACID_21630 0.0 1105.9 Propionibacteriales rnj GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GIW7@201174,4DMZI@85009,COG0595@1,COG0595@2 NA|NA|NA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay gnl|extdb|FAM19036-p1-1.1_001031 1171373.PACID_21620 7.9e-30 135.6 Actinobacteria rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQNU@201174,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family gnl|extdb|FAM19036-p1-1.1_001032 1171373.PACID_21600 3.6e-82 310.8 Bacteria ko:K03976 ko00000,ko01000,ko03016 Bacteria COG2606@1,COG2606@2 NA|NA|NA S Cys-tRNA(Pro) hydrolase activity gnl|extdb|FAM19036-p1-1.1_001033 1171373.PACID_21610 0.0 1479.9 Propionibacteriales recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKA3@201174,4DNNB@85009,COG1200@1,COG1200@2 NA|NA|NA L ATP-dependent DNA helicase RecG gnl|extdb|FAM19036-p1-1.1_001034 1171373.PACID_21590 1.4e-77 295.4 Propionibacteriales ko:K07005 ko00000 Bacteria 2IQ9Y@201174,4DVJV@85009,COG3467@1,COG3467@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase gnl|extdb|FAM19036-p1-1.1_001035 1171373.PACID_21580 1.3e-106 392.5 Propionibacteriales rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2GQ3G@201174,4DQZ1@85009,COG0742@1,COG0742@2 NA|NA|NA L Conserved hypothetical protein 95 gnl|extdb|FAM19036-p1-1.1_001036 1171373.PACID_21570 2.8e-82 311.2 Propionibacteriales coaD GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN1S@201174,4DR12@85009,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate gnl|extdb|FAM19036-p1-1.1_001037 1171373.PACID_21560 5.1e-101 373.6 Propionibacteriales yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 2GJTS@201174,4DQUU@85009,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 gnl|extdb|FAM19036-p1-1.1_001038 1171373.PACID_21550 4.8e-30 136.3 Propionibacteriales rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2GQP3@201174,4DS4H@85009,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family gnl|extdb|FAM19036-p1-1.1_001039 1171373.PACID_21540 5.4e-144 516.9 Propionibacteriales rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2GKER@201174,4DN7J@85009,COG0571@1,COG0571@2 NA|NA|NA K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism gnl|extdb|FAM19036-p1-1.1_001040 1171373.PACID_21530 6.9e-161 573.2 Propionibacteriales fpg GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJNT@201174,4DN5R@85009,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates gnl|extdb|FAM19036-p1-1.1_001041 1171373.PACID_21520 2.9e-159 567.8 Actinobacteria morA2 Bacteria 2GJQ7@201174,COG0656@1,COG0656@2 NA|NA|NA K aldo keto reductase gnl|extdb|FAM19036-p1-1.1_001042 1171373.PACID_21510 3.8e-86 323.9 Actinobacteria Bacteria 2IFSF@201174,COG1917@1,COG1917@2 NA|NA|NA IQ conserved protein, contains double-stranded beta-helix domain gnl|extdb|FAM19036-p1-1.1_001044 1171373.PACID_21490 1.1e-65 255.8 Actinobacteria Bacteria 2IR4U@201174,COG4334@1,COG4334@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2255) gnl|extdb|FAM19036-p1-1.1_001045 1171373.PACID_21480 4.8e-160 570.5 Propionibacteriales Bacteria 2GJS3@201174,4DQCP@85009,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM19036-p1-1.1_001049 1171373.PACID_21400 2.4e-217 761.1 Actinobacteria Bacteria 2GP6Q@201174,COG0627@1,COG0627@2 NA|NA|NA S Esterase gnl|extdb|FAM19036-p1-1.1_001050 1171373.PACID_21390 2.5e-241 841.3 Propionibacteriales ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2GK4R@201174,4DNUI@85009,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY gnl|extdb|FAM19036-p1-1.1_001051 1171373.PACID_21380 5.9e-227 793.1 Propionibacteriales 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKRZ@201174,4DP0W@85009,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family gnl|extdb|FAM19036-p1-1.1_001052 1171373.PACID_21370 1.8e-66 258.5 Propionibacteriales rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IKU0@201174,4DQZU@85009,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family gnl|extdb|FAM19036-p1-1.1_001053 1171373.PACID_21360 3.7e-38 163.7 Propionibacteriales CP_0960 GO:0008150,GO:0040007 ko:K06960 ko00000 Bacteria 2IQ4C@201174,4DSI2@85009,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family gnl|extdb|FAM19036-p1-1.1_001054 1171373.PACID_21350 2.4e-90 338.2 Propionibacteriales rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 2GK4I@201174,4DRZ5@85009,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes gnl|extdb|FAM19036-p1-1.1_001057 1171373.PACID_21320 0.0 1390.2 Propionibacteriales sdhA 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ45@201174,4DN0E@85009,COG1053@1,COG1053@2 NA|NA|NA C succinate dehydrogenase gnl|extdb|FAM19036-p1-1.1_001058 1171373.PACID_21310 1.3e-145 522.3 Propionibacteriales frdB 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJPS@201174,4DPU6@85009,COG0479@1,COG0479@2 NA|NA|NA C Succinate dehydrogenase fumarate reductase gnl|extdb|FAM19036-p1-1.1_001059 1171373.PACID_21300 2e-58 231.5 Propionibacteriales rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRT@201174,4DQSW@85009,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site gnl|extdb|FAM19036-p1-1.1_001060 1171373.PACID_21290 1.1e-147 529.3 Propionibacteriales lepB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GIYN@201174,4DQK9@85009,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family gnl|extdb|FAM19036-p1-1.1_001062 1171373.PACID_21270 4.2e-52 210.3 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2AFXT@1,2IKPZ@201174,3161G@2,4DR0E@85009 NA|NA|NA S Protein of unknown function (DUF2469) gnl|extdb|FAM19036-p1-1.1_001063 1171373.PACID_21260 2.8e-78 297.7 Propionibacteriales yraN ko:K07460 ko00000 Bacteria 2IQ3X@201174,4DRQN@85009,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family gnl|extdb|FAM19036-p1-1.1_001064 1171373.PACID_21250 2.1e-285 987.6 Propionibacteriales comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K06400,ko:K07391 ko00000 Bacteria 2GJIQ@201174,4DNC3@85009,COG0606@1,COG0606@2 NA|NA|NA O Magnesium chelatase, subunit ChlI C-terminal gnl|extdb|FAM19036-p1-1.1_001065 1171373.PACID_21240 1.2e-216 758.8 Propionibacteriales dprA 5.99.1.2 ko:K03168,ko:K04096 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKDA@201174,4DUGW@85009,COG0758@1,COG0758@2 NA|NA|NA LU DNA recombination-mediator protein A gnl|extdb|FAM19036-p1-1.1_001066 1171373.PACID_21230 9.3e-308 1062.0 Actinobacteria araB 2.7.1.16,2.7.1.17,2.7.1.5 ko:K00848,ko:K00853,ko:K00854 ko00040,ko00051,ko01100,ko01120,map00040,map00051,map01100,map01120 M00014 R01526,R01639,R01902,R02439,R03014 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 2GVSJ@201174,COG1070@1,COG1070@2 NA|NA|NA G Carbohydrate kinase gnl|extdb|FAM19036-p1-1.1_001067 1171373.PACID_21220 2.4e-305 1053.9 Propionibacteriales abfA 3.2.1.55 ko:K01209 ko00520,map00520 R01762 ko00000,ko00001,ko01000 GH51 Bacteria 2GMAK@201174,4DPIB@85009,COG3534@1,COG3534@2 NA|NA|NA G Alpha-L-arabinofuranosidase C-terminus gnl|extdb|FAM19036-p1-1.1_001069 1171373.PACID_21200 2.6e-172 611.3 Propionibacteriales amyD ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GKJI@201174,4DTAT@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001070 1171373.PACID_21190 2e-155 555.1 Propionibacteriales ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 Bacteria 2GITV@201174,4DPGZ@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001071 1170318.PALO_00335 1.3e-188 665.6 Propionibacteriales Bacteria 2GJ5Q@201174,4DN1S@85009,COG1609@1,COG1609@2 NA|NA|NA K periplasmic binding protein LacI transcriptional regulator gnl|extdb|FAM19036-p1-1.1_001072 1171373.PACID_21170 0.0 1272.3 Propionibacteriales ko:K09955 ko00000 Bacteria 2GM60@201174,4DPBU@85009,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 gnl|extdb|FAM19036-p1-1.1_001073 1284679.HMPREF1626_07985 3.2e-99 368.2 Actinobacteria ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJNN@201174,COG0395@1,COG0395@2 NA|NA|NA G PFAM binding-protein-dependent transport systems inner membrane component gnl|extdb|FAM19036-p1-1.1_001076 1171373.PACID_21140 8.7e-187 659.4 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJV7@201174,4DPZH@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_001078 1171373.PACID_21110 6.4e-136 490.0 Propionibacteriales araD 4.1.2.17,4.1.2.19,5.1.3.4 ko:K01628,ko:K01629,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R01785,R02262,R02263,R05850 RC00438,RC00599,RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNI6@201174,4DNAZ@85009,COG0235@1,COG0235@2 NA|NA|NA G Class II Aldolase and Adducin N-terminal domain gnl|extdb|FAM19036-p1-1.1_001079 1171373.PACID_21100 1.9e-294 1017.7 Propionibacteriales araA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 R01761 RC00516 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060 Bacteria 2GJNB@201174,4DPD0@85009,COG2160@1,COG2160@2 NA|NA|NA G Catalyzes the conversion of L-arabinose to L-ribulose gnl|extdb|FAM19036-p1-1.1_001080 1171373.PACID_21090 1.5e-186 658.7 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4DQ8P@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_001082 1171373.PACID_21040 1.1e-261 908.7 Propionibacteriales dapE2 Bacteria 2GKKW@201174,4DNTG@85009,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain gnl|extdb|FAM19036-p1-1.1_001083 1171373.PACID_21030 2.2e-251 874.4 Propionibacteriales gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GKST@201174,4DWPU@85009,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain gnl|extdb|FAM19036-p1-1.1_001084 1171373.PACID_21020 1e-176 625.9 Propionibacteriales Bacteria 2GMNA@201174,4DPF5@85009,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM19036-p1-1.1_001085 1171373.PACID_21010 1.5e-106 392.1 Propionibacteriales Bacteria 298YA@1,2GIYI@201174,2ZW25@2,4DQQ2@85009 NA|NA|NA S Protein of unknown function (DUF3090) gnl|extdb|FAM19036-p1-1.1_001086 1171373.PACID_21000 6.5e-122 443.4 Propionibacteriales pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 2GMBT@201174,4DQFV@85009,COG3201@1,COG3201@2 NA|NA|NA H Nicotinamide mononucleotide transporter gnl|extdb|FAM19036-p1-1.1_001087 1171373.PACID_20990 2.4e-40 171.0 Propionibacteriales hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860 Bacteria 2IQ4D@201174,4DRHZ@85009,COG0140@1,COG0140@2 NA|NA|NA E phosphoribosyl-ATP diphosphatase activity gnl|extdb|FAM19036-p1-1.1_001088 1171373.PACID_20980 6.7e-156 556.6 Propionibacteriales hisG GO:0000105,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003879,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0052803,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNAX@201174,4DTZ7@85009,COG0040@1,COG0040@2 NA|NA|NA E ATP phosphoribosyltransferase gnl|extdb|FAM19036-p1-1.1_001090 1171373.PACID_20960 2.8e-82 311.2 Bacteria Bacteria 2DYNQ@1,34AGE@2 NA|NA|NA S SseB protein N-terminal domain gnl|extdb|FAM19036-p1-1.1_001095 1171373.PACID_20920 2.5e-108 398.3 Propionibacteriales Bacteria 2GKX5@201174,4DNAU@85009,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat gnl|extdb|FAM19036-p1-1.1_001096 1171373.PACID_20910 1.5e-183 648.7 Propionibacteriales yutF GO:0000121,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030145,GO:0042578,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0071704,GO:1901575 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 R03024 RC00151 ko00000,ko00001,ko01000 Bacteria 2GK7V@201174,4DPB1@85009,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase gnl|extdb|FAM19036-p1-1.1_001097 1171373.PACID_20900 4.9e-92 344.0 Propionibacteriales bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 2GJ53@201174,4DRM2@85009,COG1268@1,COG1268@2 NA|NA|NA S BioY family gnl|extdb|FAM19036-p1-1.1_001098 1171373.PACID_20890 2.5e-124 451.4 Propionibacteriales ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4DQ9U@85009,COG1122@1,COG1122@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_001099 1171373.PACID_20880 2.6e-115 421.4 Actinobacteria bioN ko:K16783 ko02010,map02010 M00581 ko00000,ko00001,ko00002,ko02000 3.A.1.25.1 Bacteria 2IQMQ@201174,COG0619@1,COG0619@2 NA|NA|NA P ABC-type cobalt transport system permease component CbiQ gnl|extdb|FAM19036-p1-1.1_001100 1171373.PACID_20870 2.4e-130 471.5 Propionibacteriales tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 2GJVT@201174,4DPUY@85009,COG1189@1,COG1189@2 NA|NA|NA J FtsJ-like methyltransferase gnl|extdb|FAM19036-p1-1.1_001102 1171373.PACID_20850 6.1e-294 1016.1 Propionibacteriales recN GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 2GIVG@201174,4DN95@85009,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA gnl|extdb|FAM19036-p1-1.1_001103 1171373.PACID_20840 0.0 1139.4 Propionibacteriales pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 2GJ13@201174,4DP71@85009,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates gnl|extdb|FAM19036-p1-1.1_001104 1171373.PACID_20830 9.3e-135 486.1 Propionibacteriales nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 2GNW6@201174,4DR6U@85009,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain gnl|extdb|FAM19036-p1-1.1_001105 1171373.PACID_20820 1.3e-168 599.0 Propionibacteriales xerD GO:0008150,GO:0040007 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4DNSC@85009,COG4974@1,COG4974@2 NA|NA|NA L tyrosine recombinase gnl|extdb|FAM19036-p1-1.1_001106 1171373.PACID_20810 2.7e-171 607.8 Propionibacteriales soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GJX3@201174,4DP0V@85009,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ gnl|extdb|FAM19036-p1-1.1_001107 1171373.PACID_20800 2.8e-55 221.1 Propionibacteriales Bacteria 2E3JK@1,2GS0Y@201174,32YHZ@2,4DRQ0@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001108 1171373.PACID_20790 7.1e-138 496.5 Propionibacteriales rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2GJ4N@201174,4DNT7@85009,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family gnl|extdb|FAM19036-p1-1.1_001110 1171373.PACID_20770 1.7e-198 698.4 Actinobacteria gluQ 6.1.1.17 ko:K01885,ko:K01894 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 2GKMT@201174,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gnl|extdb|FAM19036-p1-1.1_001111 1171373.PACID_20760 6.3e-182 643.3 Propionibacteriales pafB ko:K13572 ko00000,ko03051 Bacteria 2GM46@201174,4DNBD@85009,COG2378@1,COG2378@2 NA|NA|NA K WYL domain gnl|extdb|FAM19036-p1-1.1_001112 1171373.PACID_20750 1.5e-172 612.1 Propionibacteriales pafC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K13573 ko00000,ko03051 Bacteria 2GMAU@201174,4DP7N@85009,COG2378@1,COG2378@2 NA|NA|NA K WYL domain gnl|extdb|FAM19036-p1-1.1_001117 1171373.PACID_20700 0.0 1781.5 Propionibacteriales helY GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K03727 ko00000,ko01000 Bacteria 2GJEX@201174,4DN1B@85009,COG4581@1,COG4581@2 NA|NA|NA L DSHCT gnl|extdb|FAM19036-p1-1.1_001118 1171373.PACID_20690 2.8e-137 494.6 Propionibacteriales hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRP@201174,4DPEF@85009,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit gnl|extdb|FAM19036-p1-1.1_001119 1171373.PACID_20680 1e-66 259.2 Actinobacteria hit ko:K02503 ko00000,ko04147 Bacteria 2IHPT@201174,COG0537@1,COG0537@2 NA|NA|NA FG Histidine triad (Hit) protein gnl|extdb|FAM19036-p1-1.1_001120 1171373.PACID_20670 0.0 1193.7 Propionibacteriales ilvB 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKU4@201174,4DNJX@85009,COG0028@1,COG0028@2 NA|NA|NA E Thiamine pyrophosphate enzyme, central domain gnl|extdb|FAM19036-p1-1.1_001121 1171373.PACID_20650 9.2e-84 316.2 Propionibacteriales ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ilvN,iJN678.ilvN Bacteria 2GJCH@201174,4DQCD@85009,COG0440@1,COG0440@2 NA|NA|NA E Acetolactate synthase gnl|extdb|FAM19036-p1-1.1_001122 1171373.PACID_20640 4.2e-197 693.7 Propionibacteriales ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXA@201174,4DNFA@85009,COG0059@1,COG0059@2 NA|NA|NA EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate gnl|extdb|FAM19036-p1-1.1_001123 1171373.PACID_20630 4.6e-105 387.1 Propionibacteriales Bacteria 2I80B@201174,4DQJK@85009,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase activity gnl|extdb|FAM19036-p1-1.1_001124 1171373.PACID_20620 6.9e-90 336.7 Propionibacteriales Bacteria 2EBIV@1,2IHZS@201174,335JA@2,4DRF2@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001125 1171373.PACID_20610 1.3e-189 669.5 Propionibacteriales yuaG ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 Bacteria 2GK9I@201174,4DNKB@85009,COG2268@1,COG2268@2 NA|NA|NA S Flotillin gnl|extdb|FAM19036-p1-1.1_001126 1171373.PACID_20600 1.5e-192 678.7 Propionibacteriales leuB 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GK44@201174,4DPJF@85009,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate gnl|extdb|FAM19036-p1-1.1_001127 1171373.PACID_20590 5.6e-208 729.9 Propionibacteriales ilvE GO:0000082,GO:0000278,GO:0003674,GO:0003824,GO:0004084,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006573,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008283,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009082,GO:0009083,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0022402,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903047 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKJ1@201174,4DPRZ@85009,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase gnl|extdb|FAM19036-p1-1.1_001128 1171373.PACID_20580 1.6e-304 1051.2 Propionibacteriales cimA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GKYT@201174,4DNDJ@85009,COG0119@1,COG0119@2 NA|NA|NA E Belongs to the alpha-IPM synthase homocitrate synthase family gnl|extdb|FAM19036-p1-1.1_001129 1171373.PACID_20570 1.5e-231 808.5 Propionibacteriales deoA GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iHN637.CLJU_RS08925,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 Bacteria 2GJH5@201174,4DNE9@85009,COG0213@1,COG0213@2 NA|NA|NA F Pyrimidine nucleoside phosphorylase C-terminal domain gnl|extdb|FAM19036-p1-1.1_001130 1171373.PACID_20560 2.3e-150 538.1 Propionibacteriales fahA Bacteria 2GN2G@201174,4DPHV@85009,COG0179@1,COG0179@2 NA|NA|NA Q Domain of unknown function (DUF2437) gnl|extdb|FAM19036-p1-1.1_001131 1171373.PACID_20550 4.8e-171 607.1 Propionibacteriales ko:K07052 ko00000 Bacteria 2GR9Y@201174,4DWVR@85009,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM19036-p1-1.1_001134 1171373.PACID_20520 9.1e-122 443.0 Propionibacteriales ltbR Bacteria 2GKB0@201174,4DP77@85009,COG1414@1,COG1414@2 NA|NA|NA K helix_turn_helix isocitrate lyase regulation gnl|extdb|FAM19036-p1-1.1_001135 1171373.PACID_20510 1.3e-273 948.3 Propionibacteriales leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0030312,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531 Bacteria 2GKT7@201174,4DNZM@85009,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate gnl|extdb|FAM19036-p1-1.1_001136 1171373.PACID_20500 7e-112 409.8 Propionibacteriales leuD GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2987c Bacteria 2GJ8Z@201174,4DPSM@85009,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate gnl|extdb|FAM19036-p1-1.1_001137 1171373.PACID_20490 2.2e-147 528.1 Propionibacteriales plsC2 Bacteria 2GKVA@201174,4DQUS@85009,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases gnl|extdb|FAM19036-p1-1.1_001139 1122998.AUHZ01000015_gene105 3.9e-41 174.5 Propionibacteriales Bacteria 2CQFE@1,2GRVK@201174,32SM3@2,4DS6W@85009 NA|NA|NA S Protein of unknown function (DUF3515) gnl|extdb|FAM19036-p1-1.1_001140 1171373.PACID_20450 4.5e-177 627.1 Propionibacteriales thiL GO:0008150,GO:0040007 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2977c,iYO844.BSU05900 Bacteria 2GP6E@201174,4DNV9@85009,COG0611@1,COG0611@2 NA|NA|NA H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 gnl|extdb|FAM19036-p1-1.1_001142 1171373.PACID_20430 1.3e-101 375.9 Bacteria Bacteria COG3152@1,COG3152@2 NA|NA|NA L Membrane gnl|extdb|FAM19036-p1-1.1_001143 1171373.PACID_20420 3.9e-90 337.8 Actinobacteria Bacteria 2IQHK@201174,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) gnl|extdb|FAM19036-p1-1.1_001144 1171373.PACID_20410 3.6e-83 314.3 Actinobacteria Bacteria 2IQHK@201174,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) gnl|extdb|FAM19036-p1-1.1_001146 1171373.PACID_20390 1.4e-201 708.8 Propionibacteriales prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2GJ0F@201174,4DPCH@85009,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA gnl|extdb|FAM19036-p1-1.1_001147 1171373.PACID_20380 2.9e-125 454.5 Propionibacteriales ftsE GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJE1@201174,4DNHN@85009,COG2884@1,COG2884@2 NA|NA|NA D cell division ATP-binding protein FtsE gnl|extdb|FAM19036-p1-1.1_001148 1171373.PACID_20370 3.5e-149 534.3 Propionibacteriales ftsX GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJMA@201174,4DQWR@85009,COG2177@1,COG2177@2 NA|NA|NA D Part of the ABC transporter FtsEX involved in cellular division gnl|extdb|FAM19036-p1-1.1_001149 1171373.PACID_20360 1e-84 319.3 Propionibacteriales smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 2GJX1@201174,4DQQA@85009,COG0691@1,COG0691@2 NA|NA|NA O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA gnl|extdb|FAM19036-p1-1.1_001151 1171373.PACID_20340 1.4e-212 745.3 Propionibacteriales argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIW0@201174,4DN1T@85009,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate gnl|extdb|FAM19036-p1-1.1_001152 1171373.PACID_20330 2.5e-172 611.3 Propionibacteriales argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784 Bacteria 2GKDS@201174,4DPCE@85009,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily gnl|extdb|FAM19036-p1-1.1_001153 1171373.PACID_20320 2.4e-231 807.7 Propionibacteriales argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKE9@201174,4DNMX@85009,COG4992@1,COG4992@2 NA|NA|NA E Aminotransferase class-III gnl|extdb|FAM19036-p1-1.1_001154 1171373.PACID_20310 3.7e-168 597.4 Propionibacteriales argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ6H@201174,4DNNE@85009,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline gnl|extdb|FAM19036-p1-1.1_001155 1171373.PACID_20300 1.2e-266 925.2 Propionibacteriales argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argH Bacteria 2GJ2A@201174,4DPEP@85009,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase gnl|extdb|FAM19036-p1-1.1_001156 1171373.PACID_20290 9.8e-115 419.5 Actinobacteria ko:K09940 ko00000 Bacteria 2IH69@201174,COG3296@1,COG3296@2 NA|NA|NA S Domain of unknown function (DUF1707) gnl|extdb|FAM19036-p1-1.1_001158 1171373.PACID_20280 1.4e-104 385.6 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07735 ko00000,ko03000 Bacteria 2GNRA@201174,4DR8I@85009,COG1678@1,COG1678@2 NA|NA|NA K Uncharacterized ACR, COG1678 gnl|extdb|FAM19036-p1-1.1_001159 1171373.PACID_20270 9.7e-132 476.1 Propionibacteriales Bacteria 2GJE6@201174,4DP53@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM19036-p1-1.1_001160 1171373.PACID_20260 4.3e-289 1000.0 Propionibacteriales mtrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.7.13.3 ko:K02484,ko:K07653,ko:K07654 ko02020,map02020 M00460,M00461 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GJ2D@201174,4DPTV@85009,COG5000@1,COG5000@2,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_001161 1122998.AUHZ01000012_gene248 6.4e-169 600.9 Propionibacteriales lpqB GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 Bacteria 2GJ5Y@201174,4DQ1Z@85009,COG5401@1,COG5401@2 NA|NA|NA M Sporulation and spore germination gnl|extdb|FAM19036-p1-1.1_001163 1171373.PACID_20230 1.7e-108 398.7 Propionibacteriales hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 2GMYF@201174,4DQCT@85009,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase gnl|extdb|FAM19036-p1-1.1_001167 767029.HMPREF9154_1513 7.9e-19 100.5 Bacteria Bacteria 2DGDU@1,2ZVJF@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001168 1171373.PACID_20180 2.4e-83 314.7 Propionibacteriales Bacteria 2GS2W@201174,4DSAG@85009,COG3832@1,COG3832@2 NA|NA|NA S Protein of unknown function (DUF2505) gnl|extdb|FAM19036-p1-1.1_001170 1171373.PACID_20160 2.4e-175 621.3 Bacteria Bacteria 2AXBP@1,31PAU@2 NA|NA|NA S IrrE N-terminal-like domain gnl|extdb|FAM19036-p1-1.1_001171 1171373.PACID_20150 1e-204 719.2 Propionibacteriales trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9A@201174,4DTIS@85009,COG0180@1,COG0180@2 NA|NA|NA J tRNA synthetases class I (W and Y) gnl|extdb|FAM19036-p1-1.1_001172 1171373.PACID_20140 2.5e-269 934.5 Propionibacteriales deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4DNNT@85009,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family gnl|extdb|FAM19036-p1-1.1_001174 1171373.PACID_20120 1.1e-33 148.7 Propionibacteriales Bacteria 2E3M2@1,2GQQW@201174,32YJA@2,4DS75@85009 NA|NA|NA S Protein of unknown function (DUF3107) gnl|extdb|FAM19036-p1-1.1_001175 1171373.PACID_20110 8.4e-157 559.7 Propionibacteriales prpB10 Bacteria 2GKDM@201174,4DN5I@85009,COG0631@1,COG0631@2 NA|NA|NA T Serine/threonine phosphatases, family 2C, catalytic domain gnl|extdb|FAM19036-p1-1.1_001176 1171373.PACID_20100 1.9e-32 144.4 Actinobacteria cspC ko:K03704 ko00000,ko03000 Bacteria 2GQRU@201174,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein gnl|extdb|FAM19036-p1-1.1_001177 1171373.PACID_20090 0.0 2040.4 Propionibacteriales uvrD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJD0@201174,4DPY8@85009,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily gnl|extdb|FAM19036-p1-1.1_001178 1171373.PACID_20080 0.0 2088.5 Propionibacteriales uvrD2 3.6.4.12 ko:K03657,ko:K07465 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GM2E@201174,4DP1P@85009,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily gnl|extdb|FAM19036-p1-1.1_001180 1171373.PACID_20070 0.0 1211.1 Propionibacteriales recD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GIX1@201174,4DPY9@85009,COG0507@1,COG0507@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD gnl|extdb|FAM19036-p1-1.1_001182 1171373.PACID_20050 0.0 1480.3 Propionibacteriales recC 3.1.11.5 ko:K03583 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNVB@201174,4DNIF@85009,COG1330@1,COG1330@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity gnl|extdb|FAM19036-p1-1.1_001183 1171373.PACID_20050 3e-94 351.3 Propionibacteriales recC 3.1.11.5 ko:K03583 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNVB@201174,4DNIF@85009,COG1330@1,COG1330@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity gnl|extdb|FAM19036-p1-1.1_001184 1171373.PACID_20050 9.8e-33 146.0 Propionibacteriales recC 3.1.11.5 ko:K03583 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNVB@201174,4DNIF@85009,COG1330@1,COG1330@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity gnl|extdb|FAM19036-p1-1.1_001185 1171373.PACID_20040 0.0 1361.3 Propionibacteriales uvrD2 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKRW@201174,4DNWV@85009,COG0210@1,COG0210@2 NA|NA|NA L HRDC domain gnl|extdb|FAM19036-p1-1.1_001187 1171373.PACID_20020 2.3e-94 351.7 Propionibacteriales ko:K07043 ko00000 Bacteria 2GMP6@201174,4DQV0@85009,COG1451@1,COG1451@2 NA|NA|NA S Protein of unknown function DUF45 gnl|extdb|FAM19036-p1-1.1_001188 1171373.PACID_20010 1.9e-264 917.9 Propionibacteriales Bacteria 2GJ9K@201174,4DN9A@85009,COG5282@1,COG5282@2 NA|NA|NA S Zincin-like metallopeptidase gnl|extdb|FAM19036-p1-1.1_001190 1171373.PACID_19990 3.5e-100 370.9 Propionibacteriales Bacteria 2DA1Q@1,2GKR3@201174,32TUF@2,4DRDD@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001191 1171373.PACID_19980 0.0 1441.8 Propionibacteriales GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.4.1.266 ko:K09118,ko:K13693 ko00000,ko01000,ko01003 GT81 Bacteria 2GMP3@201174,4DQ0K@85009,COG0589@1,COG0589@2,COG1615@1,COG1615@2 NA|NA|NA T Uncharacterised protein family (UPF0182) gnl|extdb|FAM19036-p1-1.1_001192 1171373.PACID_19980 2.2e-110 404.8 Propionibacteriales GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.4.1.266 ko:K09118,ko:K13693 ko00000,ko01000,ko01003 GT81 Bacteria 2GMP3@201174,4DQ0K@85009,COG0589@1,COG0589@2,COG1615@1,COG1615@2 NA|NA|NA T Uncharacterised protein family (UPF0182) gnl|extdb|FAM19036-p1-1.1_001193 1171373.PACID_19970 0.0 1573.1 Actinobacteria 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 2GJ5H@201174,COG1472@1,COG1472@2 NA|NA|NA G hydrolase, family 3 gnl|extdb|FAM19036-p1-1.1_001196 1171373.PACID_19940 2e-132 478.4 Actinobacteria Bacteria 2DBXI@1,2GJN1@201174,2ZBQ3@2 NA|NA|NA S membrane gnl|extdb|FAM19036-p1-1.1_001197 1171373.PACID_19930 1.8e-281 974.5 Actinobacteria ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ4B@201174,COG0747@1,COG0747@2 NA|NA|NA E Extracellular solute-binding protein, family 5 gnl|extdb|FAM19036-p1-1.1_001198 1171373.PACID_19920 5.8e-156 557.0 Propionibacteriales oppB4 ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GK0Z@201174,4DPAR@85009,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001199 1171373.PACID_19910 4e-142 510.8 Propionibacteriales oppC4 ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GNQ5@201174,4DUYT@85009,COG1173@1,COG1173@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001200 1122997.AUDD01000012_gene1970 2.5e-112 411.8 Propionibacteriales ko:K02031 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GIXV@201174,4DX38@85009,COG0444@1,COG0444@2 NA|NA|NA EP ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_001201 1122997.AUDD01000012_gene1969 9e-102 376.7 Propionibacteriales sapF ko:K02032,ko:K19230 ko01503,ko02010,ko02024,map01503,map02010,map02024 M00239,M00739 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.5 Bacteria 2H4BW@201174,4DX37@85009,COG4608@1,COG4608@2 NA|NA|NA E ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_001202 1171373.PACID_19890 3.7e-221 773.9 Propionibacteriales serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 iYL1228.KPN_03348 Bacteria 2GJGA@201174,4DPHP@85009,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM19036-p1-1.1_001203 1171373.PACID_19880 1.5e-146 525.4 Propionibacteriales hisN GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 ko:K05602 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKZZ@201174,4DNRF@85009,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family gnl|extdb|FAM19036-p1-1.1_001204 1171373.PACID_19870 2.9e-284 983.8 Propionibacteriales Bacteria 2GK9N@201174,4DT28@85009,COG2939@1,COG2939@2 NA|NA|NA E Serine carboxypeptidase gnl|extdb|FAM19036-p1-1.1_001205 1171373.PACID_19860 7.2e-186 656.4 Propionibacteriales rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 2GJ37@201174,4DNJ3@85009,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit gnl|extdb|FAM19036-p1-1.1_001206 1171373.PACID_19850 4.2e-215 753.8 Propionibacteriales aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJKX@201174,4DNC2@85009,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate gnl|extdb|FAM19036-p1-1.1_001207 1171373.PACID_19840 4.5e-95 354.0 Bacteria doxX ko:K15977 ko00000 Bacteria COG2259@1,COG2259@2 NA|NA|NA S methylamine metabolic process gnl|extdb|FAM19036-p1-1.1_001208 1171373.PACID_19830 4.8e-117 427.2 Propionibacteriales sigH GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 ko:K03088 ko00000,ko03021 Bacteria 2GJ02@201174,4DMYC@85009,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily gnl|extdb|FAM19036-p1-1.1_001209 754252.PFREUD_10210 3.3e-10 70.9 Bacteria rsrA GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 Bacteria COG5662@1,COG5662@2 NA|NA|NA K AntiSigma factor gnl|extdb|FAM19036-p1-1.1_001210 1171373.PACID_19800 6.3e-279 966.1 Propionibacteriales pdtaS GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K00936 M00839 ko00000,ko00002,ko01000,ko01001,ko02022 Bacteria 2GKMP@201174,4DPYA@85009,COG3920@1,COG3920@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_001211 1171373.PACID_19790 9.4e-42 175.6 Propionibacteriales whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K18955 ko00000,ko03000 Bacteria 2DMIE@1,2IQCG@201174,32RSG@2,4DRG4@85009 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA gnl|extdb|FAM19036-p1-1.1_001213 1171373.PACID_19770 1.9e-25 120.9 Bacteria Bacteria 2E460@1,32Z20@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001215 1171373.PACID_19750 3e-251 874.0 Actinobacteria Bacteria 2GN1J@201174,COG5650@1,COG5650@2 NA|NA|NA S Glycosyltransferase family 87 gnl|extdb|FAM19036-p1-1.1_001216 1171373.PACID_19740 1e-196 692.6 Propionibacteriales fas6 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2GKJH@201174,4DPM7@85009,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family gnl|extdb|FAM19036-p1-1.1_001218 1171373.PACID_19720 7.7e-274 949.1 Propionibacteriales lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKAI@201174,4DPUN@85009,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine gnl|extdb|FAM19036-p1-1.1_001219 1171373.PACID_19700 9e-248 862.4 Propionibacteriales hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 2GIX9@201174,4DPCG@85009,COG0460@1,COG0460@2 NA|NA|NA E Homoserine dehydrogenase gnl|extdb|FAM19036-p1-1.1_001220 1171373.PACID_19690 1.2e-166 592.4 Propionibacteriales thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 2GKIW@201174,4DP8I@85009,COG0083@1,COG0083@2 NA|NA|NA E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate gnl|extdb|FAM19036-p1-1.1_001221 1171373.PACID_19680 2.4e-268 931.4 Propionibacteriales rho GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 2GIWY@201174,4DN0N@85009,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template gnl|extdb|FAM19036-p1-1.1_001222 1171373.PACID_19670 1.1e-35 155.2 Propionibacteriales rpmE GO:0008150,GO:0040007 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ4I@201174,4DRWY@85009,COG0254@1,COG0254@2 NA|NA|NA J Binds the 23S rRNA gnl|extdb|FAM19036-p1-1.1_001225 1171373.PACID_19640 6.1e-130 470.3 Propionibacteriales ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2GK2X@201174,4DQKX@85009,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine gnl|extdb|FAM19036-p1-1.1_001226 1171373.PACID_19630 1.2e-195 689.1 Propionibacteriales tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2GIT7@201174,4DPQZ@85009,COG0472@1,COG0472@2 NA|NA|NA M Glycosyl transferase family 4 gnl|extdb|FAM19036-p1-1.1_001227 1171373.PACID_19620 1.6e-238 831.6 Actinobacteria wbbX ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 2IDYC@201174,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups gnl|extdb|FAM19036-p1-1.1_001228 1171373.PACID_19610 1.8e-257 894.8 Propionibacteriales ko:K03328 ko00000 2.A.66.2 Bacteria 2H55P@201174,4DUU7@85009,COG2244@1,COG2244@2 NA|NA|NA M Polysaccharide biosynthesis protein gnl|extdb|FAM19036-p1-1.1_001229 1171373.PACID_19600 1.1e-262 912.1 Actinobacteria flgK 3.5.1.56 ko:K02388,ko:K02390,ko:K02396,ko:K03418,ko:K07004,ko:K21012 ko00630,ko02025,ko02040,map00630,map02025,map02040 R02509 RC00111,RC00731 ko00000,ko00001,ko01000,ko02035 Bacteria 2IFH6@201174,COG1749@1,COG1749@2 NA|NA|NA N Domain of unknown function (DUF4082) gnl|extdb|FAM19036-p1-1.1_001230 1171373.PACID_19590 0.0 1191.8 Propionibacteriales Bacteria 2I5Z7@201174,4DR9J@85009,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase family 2 gnl|extdb|FAM19036-p1-1.1_001231 1122997.AUDD01000004_gene1235 3.6e-124 451.4 Actinobacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2H43R@201174,COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process gnl|extdb|FAM19036-p1-1.1_001232 1171373.PACID_19570 2.9e-117 427.9 Actinobacteria Bacteria 2EDAP@1,2GZW4@201174,33771@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001233 1171373.PACID_19560 6.1e-130 470.3 Bacteria ko:K16554 ko05111,map05111 ko00000,ko00001,ko02000 8.A.3.1 Bacteria COG3206@1,COG3206@2 NA|NA|NA M extracellular polysaccharide biosynthetic process gnl|extdb|FAM19036-p1-1.1_001234 1171373.PACID_19550 2.6e-228 797.7 Actinobacteria Bacteria 2ICRB@201174,COG3307@1,COG3307@2 NA|NA|NA M PFAM O-antigen polymerase gnl|extdb|FAM19036-p1-1.1_001235 1171373.PACID_19540 1.4e-264 918.3 Actinobacteria 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 2GSQI@201174,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase gnl|extdb|FAM19036-p1-1.1_001236 1171373.PACID_19530 1.7e-226 791.6 Bacteria VP1463 Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups gnl|extdb|FAM19036-p1-1.1_001237 1171373.PACID_19520 0.0 1252.7 Propionibacteriales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJIM@201174,4DQH7@85009,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase gnl|extdb|FAM19036-p1-1.1_001238 1171373.PACID_19510 2.9e-238 830.9 Actinobacteria Bacteria 2IDYB@201174,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM19036-p1-1.1_001239 1171373.PACID_19500 2.6e-277 960.7 Bacteria Bacteria COG2120@1,COG2120@2 NA|NA|NA S N-acetylglucosaminylinositol deacetylase activity gnl|extdb|FAM19036-p1-1.1_001240 1171373.PACID_19490 8.1e-282 975.7 Propionibacteriales Bacteria 2HF02@201174,4DTHG@85009,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain gnl|extdb|FAM19036-p1-1.1_001241 1171373.PACID_19480 2.2e-151 541.6 Bacteria Bacteria COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family gnl|extdb|FAM19036-p1-1.1_001242 1171373.PACID_19470 3.7e-182 644.0 Bacteria nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria COG0171@1,COG0171@2 NA|NA|NA H NAD+ synthase (glutamine-hydrolyzing) activity gnl|extdb|FAM19036-p1-1.1_001243 1171373.PACID_19460 0.0 1350.9 Propionibacteriales asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJIM@201174,4DQH7@85009,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase gnl|extdb|FAM19036-p1-1.1_001244 1171373.PACID_19450 1e-38 165.6 Propionibacteriales acpP-7 Bacteria 2H7G5@201174,4DW64@85009,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis gnl|extdb|FAM19036-p1-1.1_001245 1171373.PACID_19440 8.3e-81 306.6 Actinobacteria 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 2GQAY@201174,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) gnl|extdb|FAM19036-p1-1.1_001247 1171373.PACID_19420 1.7e-41 174.9 Bacteria atpI ko:K02116 ko00000,ko00194 3.A.2.1 Bacteria COG5336@1,COG5336@2 NA|NA|NA C function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex gnl|extdb|FAM19036-p1-1.1_001249 1171373.PACID_19400 4.2e-30 136.7 Propionibacteriales atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GQI6@201174,4DS2C@85009,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation gnl|extdb|FAM19036-p1-1.1_001251 1171373.PACID_19380 1.3e-140 505.8 Propionibacteriales atpH ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GMJ5@201174,4DRAU@85009,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation gnl|extdb|FAM19036-p1-1.1_001252 1171373.PACID_19370 1.4e-308 1064.7 Propionibacteriales atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2GJRJ@201174,4DNCI@85009,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit gnl|extdb|FAM19036-p1-1.1_001253 1171373.PACID_19360 5.3e-159 567.0 Propionibacteriales atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 2GJ7Q@201174,4DN4I@85009,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex gnl|extdb|FAM19036-p1-1.1_001254 1171373.PACID_19350 1.3e-276 958.4 Propionibacteriales atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 2GIY6@201174,4DMY1@85009,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits gnl|extdb|FAM19036-p1-1.1_001255 1171373.PACID_19340 5.1e-69 266.9 Bacteria atpC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria COG0355@1,COG0355@2 NA|NA|NA C proton-transporting ATP synthase activity, rotational mechanism gnl|extdb|FAM19036-p1-1.1_001256 1171373.PACID_19330 2e-83 315.1 Bacteria Bacteria 2E6YX@1,331I5@2 NA|NA|NA S Protein of unknown function (DUF2550) gnl|extdb|FAM19036-p1-1.1_001257 1171373.PACID_19320 1.7e-122 445.3 Propionibacteriales yvqK 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMHN@201174,4DNZ5@85009,COG2096@1,COG2096@2 NA|NA|NA S Cobalamin adenosyltransferase gnl|extdb|FAM19036-p1-1.1_001258 1171373.PACID_19310 1.1e-116 426.0 Propionibacteriales ppiB 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 2GN8G@201174,4DR6Z@85009,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gnl|extdb|FAM19036-p1-1.1_001259 1171373.PACID_19300 5.6e-160 570.1 Propionibacteriales ybfF ko:K01175 ko00000,ko01000 Bacteria 2I5QQ@201174,4DWZK@85009,COG2267@1,COG2267@2 NA|NA|NA I Thioesterase domain gnl|extdb|FAM19036-p1-1.1_001261 1171373.PACID_19280 1.4e-135 488.8 Propionibacteriales nucS ko:K07503 ko00000,ko01000 Bacteria 2GIYB@201174,4DN0H@85009,COG1637@1,COG1637@2 NA|NA|NA L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures gnl|extdb|FAM19036-p1-1.1_001263 1171373.PACID_19260 3.7e-84 317.4 Propionibacteriales mce 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIPR@201174,4DQPV@85009,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gnl|extdb|FAM19036-p1-1.1_001265 1171373.PACID_19240 9.4e-92 342.8 Propionibacteriales Bacteria 2IA1C@201174,4DR83@85009,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain gnl|extdb|FAM19036-p1-1.1_001266 1171373.PACID_19220 9.7e-297 1025.4 Propionibacteriales pgm GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711 Bacteria 2H1PI@201174,4DNWG@85009,COG0033@1,COG0033@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, C-terminal domain gnl|extdb|FAM19036-p1-1.1_001268 1171373.PACID_19200 1.6e-131 475.3 Propionibacteriales pgmB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009292,GO:0009294,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0033554,GO:0042221,GO:0043167,GO:0043169,GO:0044238,GO:0044764,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704 2.4.1.64,5.4.2.6 ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R02727,R02728,R11310 RC00049,RC00408 ko00000,ko00001,ko01000 GH65 Bacteria 2I2IT@201174,4DQSF@85009,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase gnl|extdb|FAM19036-p1-1.1_001270 1171373.PACID_19180 0.0 1250.7 Actinobacteria crr GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009892,GO:0009898,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045912,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071944,GO:0080090,GO:0098552,GO:0098562 ko:K02755,ko:K02756,ko:K02757,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 e_coli_core.b2417,iAF1260.b2417,iAPECO1_1312.APECO1_4128,iB21_1397.B21_02278,iBWG_1329.BWG_2179,iE2348C_1286.E2348C_2603,iEC042_1314.EC042_2626,iEC55989_1330.EC55989_2707,iECABU_c1320.ECABU_c27380,iECBD_1354.ECBD_1264,iECB_1328.ECB_02317,iECDH10B_1368.ECDH10B_2582,iECDH1ME8569_1439.ECDH1ME8569_2351,iECD_1391.ECD_02317,iECED1_1282.ECED1_2861,iECH74115_1262.ECH74115_3648,iECIAI1_1343.ECIAI1_2475,iECIAI39_1322.ECIAI39_2563,iECNA114_1301.ECNA114_2494,iECO103_1326.ECO103_2936,iECO111_1330.ECO111_3147,iECO26_1355.ECO26_3470,iECOK1_1307.ECOK1_2734,iECS88_1305.ECS88_2607,iECSE_1348.ECSE_2708,iECSF_1327.ECSF_2281,iECSP_1301.ECSP_3365,iECUMN_1333.ECUMN_2739,iECW_1372.ECW_m2646,iEKO11_1354.EKO11_1311,iETEC_1333.ETEC_2530,iEcDH1_1363.EcDH1_1244,iEcE24377_1341.EcE24377A_2704,iEcHS_1320.EcHS_A2552,iEcSMS35_1347.EcSMS35_2572,iEcolC_1368.EcolC_1261,iG2583_1286.G2583_2949,iJO1366.b2417,iJR904.b2417,iLF82_1304.LF82_0357,iNRG857_1313.NRG857_12120,iSFV_1184.SFV_2469,iSF_1195.SF2472,iSFxv_1172.SFxv_2721,iSSON_1240.SSON_2506,iS_1188.S2618,iUMN146_1321.UM146_04535,iUMNK88_1353.UMNK88_3019,iUTI89_1310.UTI89_C2751,iWFL_1372.ECW_m2646,iY75_1357.Y75_RS12665,ic_1306.c2952 Bacteria 2GK6B@201174,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G Pts system gnl|extdb|FAM19036-p1-1.1_001271 1171373.PACID_19160 0.0 1404.0 Propionibacteriales glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 2GJ5C@201174,4DPZS@85009,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position gnl|extdb|FAM19036-p1-1.1_001274 1171373.PACID_19130 0.0 1749.9 Propionibacteriales glgP GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1,2.4.1.8 ko:K00688,ko:K00691 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R01555,R02111 RC00049 ko00000,ko00001,ko01000 GH65,GT35 Bacteria 2GIVZ@201174,4DPQE@85009,COG0058@1,COG0058@2 NA|NA|NA G Protein of unknown function (DUF3417) gnl|extdb|FAM19036-p1-1.1_001275 1171373.PACID_19100 0.0 1456.0 Propionibacteriales glgX 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2GJ00@201174,4DPSB@85009,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family gnl|extdb|FAM19036-p1-1.1_001276 1171373.PACID_19090 1.2e-200 705.7 Propionibacteriales iscS GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2GKUT@201174,4DNQT@85009,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V gnl|extdb|FAM19036-p1-1.1_001277 1171373.PACID_19080 4.5e-205 720.3 Propionibacteriales mnmA 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 2GIUQ@201174,4DPXG@85009,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 gnl|extdb|FAM19036-p1-1.1_001278 1171373.PACID_19070 7e-165 586.6 Propionibacteriales 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMPS@201174,4DN0J@85009,COG0620@1,COG0620@2 NA|NA|NA E Methionine synthase, vitamin-B12 independent gnl|extdb|FAM19036-p1-1.1_001280 1171373.PACID_19050 7.5e-138 496.5 Actinobacteria ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2GN33@201174,COG1116@1,COG1116@2 NA|NA|NA P ABC transporter gnl|extdb|FAM19036-p1-1.1_001281 1171373.PACID_19040 3.3e-122 444.5 Actinobacteria Z012_04125 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K15599 ko02010,map02010 M00442 ko00000,ko00001,ko00002,ko02000 3.A.1.17.3,3.A.1.17.6 Bacteria 2GKKZ@201174,COG0600@1,COG0600@2 NA|NA|NA P ABC-type nitrate sulfonate bicarbonate transport system permease component gnl|extdb|FAM19036-p1-1.1_001282 1171373.PACID_19030 5.6e-178 630.2 Bacteria ko:K02051,ko:K15598 ko02010,map02010 M00188,M00442 ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6 Bacteria COG0715@1,COG0715@2 NA|NA|NA P thiamine-containing compound biosynthetic process gnl|extdb|FAM19036-p1-1.1_001284 1171373.PACID_19010 5e-113 413.7 Propionibacteriales ilvA 1.3.1.12,4.3.1.19 ko:K01754,ko:K04517 ko00260,ko00290,ko00400,ko00401,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map00400,map00401,map01100,map01110,map01130,map01200,map01230 M00025,M00570 R00220,R00996,R01728 RC00125,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 2I3KF@201174,4DR5N@85009,COG2061@1,COG2061@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA gnl|extdb|FAM19036-p1-1.1_001285 1171373.PACID_19000 9.8e-46 189.1 Actinobacteria gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2IQJN@201174,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gnl|extdb|FAM19036-p1-1.1_001286 1171373.PACID_18990 7.2e-286 989.2 Propionibacteriales gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJK5@201174,4DN5B@85009,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gnl|extdb|FAM19036-p1-1.1_001287 1171373.PACID_18980 1.3e-282 978.4 Propionibacteriales gatB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJJH@201174,4DNB4@85009,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gnl|extdb|FAM19036-p1-1.1_001289 1171373.PACID_18960 4.6e-117 427.2 Propionibacteriales 1.17.1.9,1.7.7.2 ko:K00123,ko:K00367,ko:K18558 ko00630,ko00680,ko00720,ko00910,ko01100,ko01120,ko01200,map00630,map00680,map00720,map00910,map01100,map01120,map01200 M00173,M00531 R00402,R00519,R00791 RC00045,RC02796,RC02812 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ62@201174,4DR20@85009,COG0243@1,COG0243@2 NA|NA|NA C molybdopterin cofactor binding gnl|extdb|FAM19036-p1-1.1_001290 1171373.PACID_26740 4.4e-241 840.5 Propionibacteriales Bacteria 2GU7G@201174,4DQSY@85009,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases gnl|extdb|FAM19036-p1-1.1_001291 1171373.PACID_18290 2.4e-62 244.6 Propionibacteriales hisI GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1606 Bacteria 2IKKU@201174,4DR51@85009,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP gnl|extdb|FAM19036-p1-1.1_001292 1171373.PACID_18280 4.1e-300 1036.6 Propionibacteriales trpE 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJT@201174,4DQ56@85009,COG0147@1,COG0147@2 NA|NA|NA E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia gnl|extdb|FAM19036-p1-1.1_001293 1171373.PACID_18270 6.4e-97 360.1 Bacteria Bacteria 2EGC7@1,33A40@2 NA|NA|NA S Trp biosynthesis associated, transmembrane protein, oprn chp gnl|extdb|FAM19036-p1-1.1_001294 1120954.ATXE01000002_gene1072 1.1e-12 79.0 Propionibacteriales Bacteria 290XR@1,2HZG0@201174,31XZ9@2,4DSNF@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001295 1171373.PACID_18250 2.7e-138 498.0 Propionibacteriales trpC GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.20 ko:K01609,ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03508 RC00209,RC00210,RC00700,RC00701,RC00944,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIVV@201174,4DNTB@85009,COG0134@1,COG0134@2 NA|NA|NA E Indole-3-glycerol phosphate synthase gnl|extdb|FAM19036-p1-1.1_001297 1171373.PACID_18230 2e-152 545.0 Propionibacteriales trpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN6T@201174,4DNGE@85009,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate gnl|extdb|FAM19036-p1-1.1_001298 1171373.PACID_18220 1.3e-168 599.0 Propionibacteriales lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 2GKSS@201174,4DP3T@85009,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins gnl|extdb|FAM19036-p1-1.1_001299 1171373.PACID_18210 0.0 3003.4 Propionibacteriales gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 2GN09@201174,4DP8G@85009,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2 NA|NA|NA E GXGXG motif gnl|extdb|FAM19036-p1-1.1_001300 1171373.PACID_18200 9.7e-288 995.3 Propionibacteriales gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 2GJ0A@201174,4DNI1@85009,COG0493@1,COG0493@2 NA|NA|NA E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gnl|extdb|FAM19036-p1-1.1_001301 1171373.PACID_18190 1.1e-184 652.5 Propionibacteriales celR ko:K02529 ko00000,ko03000 Bacteria 2GJV7@201174,4DPSW@85009,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein domain gnl|extdb|FAM19036-p1-1.1_001304 1171373.PACID_18160 6.3e-171 606.7 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GMV4@201174,4DN9U@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001305 1171373.PACID_18150 4.6e-241 840.1 Propionibacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4DNPR@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_001307 1171373.PACID_18130 3.1e-119 434.5 Bacteria Bacteria COG3247@1,COG3247@2 NA|NA|NA U response to pH gnl|extdb|FAM19036-p1-1.1_001308 1171373.PACID_18120 0.0 2406.7 Propionibacteriales dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ1P@201174,4DTRE@85009,COG0587@1,COG0587@2 NA|NA|NA L Bacterial DNA polymerase III alpha subunit gnl|extdb|FAM19036-p1-1.1_001309 1171373.PACID_18110 1.1e-95 355.9 Propionibacteriales Bacteria 2EGQJ@1,2GY1F@201174,33AGQ@2,4DSTI@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001310 1171373.PACID_18100 2e-236 824.7 Propionibacteriales hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1599 Bacteria 2GKKA@201174,4DMY2@85009,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine gnl|extdb|FAM19036-p1-1.1_001311 1171373.PACID_18090 5.7e-222 776.5 Propionibacteriales hisC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ9W@201174,4DPP5@85009,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily gnl|extdb|FAM19036-p1-1.1_001312 1171373.PACID_18080 1.1e-110 406.0 Propionibacteriales hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 2GKMD@201174,4DNSZ@85009,COG0131@1,COG0131@2 NA|NA|NA E Imidazoleglycerol-phosphate dehydratase gnl|extdb|FAM19036-p1-1.1_001313 1171373.PACID_18070 6.3e-119 433.3 Propionibacteriales hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIYS@201174,4DPJU@85009,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR gnl|extdb|FAM19036-p1-1.1_001314 1171373.PACID_18060 7.8e-140 503.1 Propionibacteriales hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4V@201174,4DMXV@85009,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase gnl|extdb|FAM19036-p1-1.1_001315 1171373.PACID_18050 9e-131 473.0 Propionibacteriales yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2GJ4G@201174,4DN3U@85009,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein gnl|extdb|FAM19036-p1-1.1_001316 1171373.PACID_18040 1.3e-96 359.0 Propionibacteriales ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJI5@201174,4DQAA@85009,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group gnl|extdb|FAM19036-p1-1.1_001317 1171373.PACID_18030 1.8e-102 378.6 Propionibacteriales ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GN17@201174,4DQ7Y@85009,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB gnl|extdb|FAM19036-p1-1.1_001318 1171373.PACID_18020 2.9e-190 671.0 Propionibacteriales ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJZF@201174,4DP63@85009,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing gnl|extdb|FAM19036-p1-1.1_001319 1171373.PACID_18010 3e-64 251.1 Propionibacteriales yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GXK0@201174,4DSPJ@85009,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase subunit gnl|extdb|FAM19036-p1-1.1_001320 1171373.PACID_18000 1.2e-308 1065.1 Propionibacteriales secD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2GJTT@201174,4DP94@85009,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA gnl|extdb|FAM19036-p1-1.1_001321 1171373.PACID_17990 5.3e-193 680.2 Propionibacteriales secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2GJRS@201174,4DPBJ@85009,COG0341@1,COG0341@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA gnl|extdb|FAM19036-p1-1.1_001322 1171373.PACID_17980 3e-93 347.8 Propionibacteriales apt 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 2IM7C@201174,4DQZW@85009,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis gnl|extdb|FAM19036-p1-1.1_001323 1171373.PACID_17970 1.8e-193 681.8 Propionibacteriales ko:K10716 ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 2GKB8@201174,4DPPQ@85009,COG1226@1,COG1226@2 NA|NA|NA P Ion channel gnl|extdb|FAM19036-p1-1.1_001324 1171373.PACID_17960 0.0 1544.6 Propionibacteriales relA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 Bacteria 2GJYQ@201174,4DNJH@85009,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance gnl|extdb|FAM19036-p1-1.1_001325 1171373.PACID_17950 4.1e-267 926.8 Actinobacteria thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRY@201174,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase gnl|extdb|FAM19036-p1-1.1_001326 1171373.PACID_17940 1.6e-214 751.9 Propionibacteriales Bacteria 2GJBD@201174,4DNC8@85009,COG1196@1,COG1196@2 NA|NA|NA D Domain of Unknown Function (DUF349) gnl|extdb|FAM19036-p1-1.1_001328 1171373.PACID_17920 1.8e-259 901.4 Propionibacteriales hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIYJ@201174,4DP1N@85009,COG0124@1,COG0124@2 NA|NA|NA J Histidine--tRNA ligase gnl|extdb|FAM19036-p1-1.1_001330 1171373.PACID_17900 1.4e-116 425.6 Actinobacteria Bacteria 2GP92@201174,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_001331 1171373.PACID_17890 4.7e-199 700.3 Actinobacteria Bacteria 28IW2@1,2IA78@201174,2Z8UC@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001332 1171373.PACID_17880 5.8e-163 580.1 Propionibacteriales 3.4.11.5 ko:K01259,ko:K06889,ko:K21193 ko00330,ko01059,map00330,map01059 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 2I2KG@201174,4DWFR@85009,COG1073@1,COG1073@2 NA|NA|NA S Alpha/beta hydrolase family gnl|extdb|FAM19036-p1-1.1_001333 1171373.PACID_17870 0.0 1225.3 Propionibacteriales aspS GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJHU@201174,4DPC4@85009,COG0173@1,COG0173@2 NA|NA|NA J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) gnl|extdb|FAM19036-p1-1.1_001334 1171373.PACID_17860 9.5e-61 239.2 Actinobacteria Bacteria 2IKXW@201174,COG3824@1,COG3824@2 NA|NA|NA S protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_001335 1171373.PACID_17850 2.6e-146 524.6 Propionibacteriales iphP 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 2GK28@201174,4DS4X@85009,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family gnl|extdb|FAM19036-p1-1.1_001336 1171373.PACID_17840 1.4e-248 865.1 Propionibacteriales rarA ko:K07478 ko00000 Bacteria 2GKDP@201174,4DP5Q@85009,COG2256@1,COG2256@2 NA|NA|NA L MgsA AAA+ ATPase C terminal gnl|extdb|FAM19036-p1-1.1_001337 1035308.AQYY01000001_gene3332 1.6e-10 74.7 Bacteria Bacteria 2DXTK@1,346GX@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001338 1171373.PACID_17820 5e-56 223.8 Propionibacteriales WQ51_05790 Bacteria 2II1J@201174,4DS6Z@85009,COG4768@1,COG4768@2 NA|NA|NA S Bacterial protein of unknown function (DUF948) gnl|extdb|FAM19036-p1-1.1_001340 1171373.PACID_17800 0.0 1751.9 Propionibacteriales alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIUG@201174,4DP1M@85009,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain gnl|extdb|FAM19036-p1-1.1_001341 1171373.PACID_17790 3.3e-74 284.3 Actinobacteria yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 2IQB0@201174,COG0816@1,COG0816@2 NA|NA|NA L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA gnl|extdb|FAM19036-p1-1.1_001342 1171373.PACID_17780 2.8e-207 727.6 Propionibacteriales mltG ko:K07082 ko00000 Bacteria 2GKGQ@201174,4DN3K@85009,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation gnl|extdb|FAM19036-p1-1.1_001343 1171373.PACID_17770 3.5e-146 524.2 Propionibacteriales aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2552c Bacteria 2GPQQ@201174,4DQSP@85009,COG0169@1,COG0169@2 NA|NA|NA E Shikimate dehydrogenase substrate binding domain gnl|extdb|FAM19036-p1-1.1_001344 1171373.PACID_17760 5.8e-222 776.5 Propionibacteriales aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976 Bacteria 2GJJN@201174,4DPU4@85009,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system gnl|extdb|FAM19036-p1-1.1_001345 1171373.PACID_17750 3.3e-95 354.4 Propionibacteriales aroK GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2GRFW@201174,4DR1Q@85009,COG0703@1,COG0703@2 NA|NA|NA E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate gnl|extdb|FAM19036-p1-1.1_001346 1171373.PACID_17740 1.8e-201 708.4 Propionibacteriales aroB GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIUZ@201174,4DN6F@85009,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) gnl|extdb|FAM19036-p1-1.1_001347 1171373.PACID_17730 2.4e-58 232.3 Bacteria ko:K21919 ko00000,ko04121 Bacteria COG1357@1,COG1357@2 NA|NA|NA S protein homooligomerization gnl|extdb|FAM19036-p1-1.1_001348 1171373.PACID_17720 8.8e-104 382.9 Propionibacteriales efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 2GJMS@201174,4DPJT@85009,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase gnl|extdb|FAM19036-p1-1.1_001350 1171373.PACID_17700 4.6e-49 200.3 Propionibacteriales mihF 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IKPU@201174,4DRRY@85009,COG0099@1,COG0099@2 NA|NA|NA J integration host factor gnl|extdb|FAM19036-p1-1.1_001351 1171373.PACID_17690 1.2e-93 349.4 Propionibacteriales gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2GK2M@201174,4DQBB@85009,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP gnl|extdb|FAM19036-p1-1.1_001352 1171373.PACID_17680 5.6e-53 213.4 Propionibacteriales rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IQHU@201174,4DRNP@85009,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gnl|extdb|FAM19036-p1-1.1_001353 1171373.PACID_17670 4.5e-222 776.9 Propionibacteriales coaBC GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJGJ@201174,4DNHQ@85009,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine gnl|extdb|FAM19036-p1-1.1_001354 1171373.PACID_17660 3.5e-227 793.9 Propionibacteriales metK GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4U@201174,4DN34@85009,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme gnl|extdb|FAM19036-p1-1.1_001355 1171373.PACID_17650 0.0 2971.4 Propionibacteriales lhr GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 ko:K03724 ko00000,ko01000,ko03400 Bacteria 2GJG3@201174,4DPDX@85009,COG1201@1,COG1201@2 NA|NA|NA L DEAD/H associated gnl|extdb|FAM19036-p1-1.1_001356 1171373.PACID_17640 6.9e-150 536.6 Propionibacteriales nei GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K05522 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKCW@201174,4DQGF@85009,COG0266@1,COG0266@2 NA|NA|NA L Formamidopyrimidine-DNA glycosylase N-terminal domain gnl|extdb|FAM19036-p1-1.1_001357 1171373.PACID_17630 4.5e-42 176.8 Propionibacteriales Bacteria 2IQ8Z@201174,4DVP8@85009,COG4118@1,COG4118@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module gnl|extdb|FAM19036-p1-1.1_001358 1171373.PACID_17620 2.9e-67 261.2 Propionibacteriales Bacteria 2IGMY@201174,4DRKE@85009,COG1487@1,COG1487@2 NA|NA|NA S PIN domain gnl|extdb|FAM19036-p1-1.1_001359 1171373.PACID_17610 2.9e-54 217.6 Bacteria ko:K07171 ko00000,ko01000,ko02048 Bacteria COG2337@1,COG2337@2 NA|NA|NA T Toxic component of a toxin-antitoxin (TA) module gnl|extdb|FAM19036-p1-1.1_001362 1171373.PACID_17590 0.0 1318.9 Propionibacteriales priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKES@201174,4DNMW@85009,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA gnl|extdb|FAM19036-p1-1.1_001363 1171373.PACID_17580 2.7e-174 617.8 Propionibacteriales fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 ko:K00604,ko:K03500 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000,ko03009 iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Bacteria 2GKH5@201174,4DN9I@85009,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus gnl|extdb|FAM19036-p1-1.1_001364 1171373.PACID_17570 7.7e-255 885.9 Propionibacteriales sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,5.3.1.9 ko:K01810,ko:K03500 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2GM21@201174,4DP4E@85009,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA JK Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family gnl|extdb|FAM19036-p1-1.1_001365 1171373.PACID_17560 1.9e-118 431.8 Propionibacteriales rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZ9@201174,4DNZI@85009,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family gnl|extdb|FAM19036-p1-1.1_001367 1171373.PACID_17540 0.0 2294.6 Actinobacteria metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM5Q@201174,COG0646@1,COG0646@2,COG1410@1,COG1410@2 NA|NA|NA E Methionine synthase gnl|extdb|FAM19036-p1-1.1_001368 1171373.PACID_17530 0.0 1077.0 Propionibacteriales trmI GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.219,2.1.1.220 ko:K07442 ko00000,ko01000,ko03016 Bacteria 2GJPD@201174,4DNGH@85009,COG0637@1,COG0637@2,COG2519@1,COG2519@2 NA|NA|NA J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA gnl|extdb|FAM19036-p1-1.1_001370 1171373.PACID_17510 3.5e-146 524.2 Propionibacteriales prcB GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 ko:K03433 ko03050,map03050 M00342,M00343 ko00000,ko00001,ko00002,ko01000,ko01002,ko03051 Bacteria 2GJ60@201174,4DPD6@85009,COG0638@1,COG0638@2 NA|NA|NA O Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation gnl|extdb|FAM19036-p1-1.1_001371 1171373.PACID_17500 3.2e-116 424.5 Propionibacteriales prcA GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 ko:K03432 ko03050,map03050 M00342,M00343 ko00000,ko00001,ko00002,ko01000,ko01002,ko03051 Bacteria 2GKZ1@201174,4DMZ3@85009,COG0638@1,COG0638@2 NA|NA|NA O Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation gnl|extdb|FAM19036-p1-1.1_001372 1171373.PACID_17490 1.9e-203 714.9 Propionibacteriales tyrA 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKB4@201174,4DNB5@85009,COG0287@1,COG0287@2 NA|NA|NA E Prephenate dehydrogenase gnl|extdb|FAM19036-p1-1.1_001373 1171373.PACID_17480 5.9e-121 440.3 Actinobacteria cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945,ko:K03977 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2H3SI@201174,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily gnl|extdb|FAM19036-p1-1.1_001374 1171373.PACID_17470 2.9e-254 884.0 Propionibacteriales der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2GJ8J@201174,4DNFK@85009,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis gnl|extdb|FAM19036-p1-1.1_001375 1171373.PACID_17460 0.0 1380.5 Propionibacteriales Bacteria 2GK30@201174,4DP18@85009,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase gnl|extdb|FAM19036-p1-1.1_001376 1171373.PACID_17450 7.8e-73 279.6 Propionibacteriales osmC ko:K04063 ko00000 Bacteria 2IFFB@201174,4DRBU@85009,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein gnl|extdb|FAM19036-p1-1.1_001377 1171373.PACID_17440 7.3e-117 426.8 Actinobacteria mutT3 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2IKSQ@201174,COG0494@1,COG0494@2 NA|NA|NA L carboxylic ester hydrolase activity gnl|extdb|FAM19036-p1-1.1_001379 1171373.PACID_17420 0.0 1550.8 Actinobacteria hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GKAQ@201174,COG0286@1,COG0286@2 NA|NA|NA V Type I restriction-modification system methyltransferase subunit gnl|extdb|FAM19036-p1-1.1_001380 1032480.MLP_45880 2e-82 312.4 Actinobacteria hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 2ISX2@201174,COG0732@1,COG0732@2 NA|NA|NA L Type I restriction modification DNA specificity domain gnl|extdb|FAM19036-p1-1.1_001381 1171373.PACID_03220 2.5e-247 860.9 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_001383 1171373.PACID_17380 0.0 1949.1 Propionibacteriales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2HI69@201174,4DPUS@85009,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification gnl|extdb|FAM19036-p1-1.1_001384 1171373.PACID_17370 9.7e-132 476.1 Bacteria ko:K07043 ko00000 Bacteria COG1451@1,COG1451@2 NA|NA|NA S Protein of unknown function DUF45 gnl|extdb|FAM19036-p1-1.1_001385 411473.RUMCAL_00631 3.9e-12 78.6 Ruminococcaceae Bacteria 1TV7M@1239,259W5@186801,29Z7W@1,30M5Y@2,3WQT2@541000 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001386 1171373.PACID_17330 1.9e-226 791.6 Bacteria GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria COG1403@1,COG1403@2 NA|NA|NA V endonuclease activity gnl|extdb|FAM19036-p1-1.1_001387 1171373.PACID_17320 1e-265 922.2 Propionibacteriales Bacteria 2I2IK@201174,4DNG5@85009,COG2227@1,COG2227@2 NA|NA|NA H RNA repair, ligase-Pnkp-associating, region of Hen1 gnl|extdb|FAM19036-p1-1.1_001388 1171373.PACID_17310 0.0 1626.7 Propionibacteriales prpA 3.1.3.16 ko:K01090 ko00000,ko01000 Bacteria 2GMB5@201174,4DNS0@85009,COG0639@1,COG0639@2,COG4639@1,COG4639@2 NA|NA|NA T PNKP adenylyltransferase domain, ligase domain gnl|extdb|FAM19036-p1-1.1_001390 1171373.PACID_17290 5.6e-59 233.4 Propionibacteriales Bacteria 2IQEW@201174,4DSDY@85009,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor gnl|extdb|FAM19036-p1-1.1_001391 1171373.PACID_17280 1.3e-98 365.5 Propionibacteriales Bacteria 2IHZ7@201174,4DQPQ@85009,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain gnl|extdb|FAM19036-p1-1.1_001392 1171373.PACID_17270 3.8e-72 277.3 Actinobacteria Bacteria 2CHCP@1,2IRB0@201174,32S5R@2 NA|NA|NA S Domain of unknown function (DU1801) gnl|extdb|FAM19036-p1-1.1_001393 1171373.PACID_17260 2.7e-66 257.7 Actinobacteria ko:K06996 ko00000 Bacteria 2IRXF@201174,COG3324@1,COG3324@2 NA|NA|NA S glyoxalase bleomycin resistance protein dioxygenase gnl|extdb|FAM19036-p1-1.1_001394 1171373.PACID_17250 1.8e-226 791.6 Propionibacteriales rocD GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 ko:K00819,ko:K00821 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 iYO844.BSU40340 Bacteria 2GK0J@201174,4DP5V@85009,COG4992@1,COG4992@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gnl|extdb|FAM19036-p1-1.1_001395 1171373.PACID_17240 2.9e-117 427.9 Actinobacteria Bacteria 2GTRU@201174,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_001396 1171373.PACID_17230 6.9e-110 404.4 Propionibacteriales Bacteria 2GK5U@201174,4DPV2@85009,COG0277@1,COG0277@2 NA|NA|NA C PFAM FAD linked oxidase domain protein gnl|extdb|FAM19036-p1-1.1_001397 1171373.PACID_17210 6.8e-84 316.6 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM19036-p1-1.1_001398 1171373.PACID_17200 4.3e-94 350.5 Propionibacteriales Bacteria 2IHSU@201174,4DRAB@85009,COG1247@1,COG1247@2 NA|NA|NA M FR47-like protein gnl|extdb|FAM19036-p1-1.1_001399 1171373.PACID_17190 1.2e-120 439.1 Propionibacteriales pksA Bacteria 2IRD6@201174,4DST5@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_001401 1171373.PACID_17160 5.9e-103 380.2 Actinobacteria dhaS Bacteria 2IJXG@201174,COG1309@1,COG1309@2 NA|NA|NA K Psort location Cytoplasmic, score gnl|extdb|FAM19036-p1-1.1_001402 1171373.PACID_17150 1e-181 642.5 Actinobacteria Bacteria 28H6R@1,2I9RC@201174,2Z7J3@2 NA|NA|NA S Psort location CytoplasmicMembrane, score gnl|extdb|FAM19036-p1-1.1_001403 1171373.PACID_17140 1.3e-176 625.5 Propionibacteriales Bacteria 2E7X6@1,2HJMK@201174,332BR@2,4DSV9@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001404 1122998.AUHZ01000007_gene2513 4.8e-49 200.7 Actinobacteria Bacteria 2EG78@1,2H7YN@201174,31B6M@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001405 1171373.PACID_17130 1.6e-166 592.0 Actinobacteria 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 2I3AM@201174,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid gnl|extdb|FAM19036-p1-1.1_001406 1171373.PACID_17120 9.7e-45 186.0 Propionibacteriales ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 2GJBE@201174,4DRE5@85009,COG1734@1,COG1734@2 NA|NA|NA T Prokaryotic dksA/traR C4-type zinc finger gnl|extdb|FAM19036-p1-1.1_001407 1171373.PACID_17110 1.2e-247 862.1 Actinobacteria 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 2IH51@201174,COG3550@1,COG3550@2 NA|NA|NA S HipA domain protein gnl|extdb|FAM19036-p1-1.1_001408 1171373.PACID_17100 1.7e-38 164.9 Bacteria ko:K07729 ko00000,ko03000 Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM19036-p1-1.1_001409 1171373.PACID_17090 1e-56 226.1 Propionibacteriales Bacteria 29ZSZ@1,2I02V@201174,30MTZ@2,4DV7M@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001410 1171373.PACID_17090 1.8e-82 312.0 Propionibacteriales Bacteria 29ZSZ@1,2I02V@201174,30MTZ@2,4DV7M@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001412 1171373.PACID_17080 7.7e-67 259.6 Propionibacteriales Bacteria 2IFDE@201174,4DQIU@85009,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein gnl|extdb|FAM19036-p1-1.1_001413 1171373.PACID_17060 1.3e-64 252.3 Actinobacteria Bacteria 2IHYP@201174,COG0346@1,COG0346@2 NA|NA|NA E glyoxalase bleomycin resistance protein dioxygenase gnl|extdb|FAM19036-p1-1.1_001416 1122998.AUHZ01000007_gene2510 3.8e-107 395.2 Actinobacteria cadA Bacteria 2GIRF@201174,COG2217@1,COG2217@2 NA|NA|NA P Heavy metal translocating P-type atpase gnl|extdb|FAM19036-p1-1.1_001417 1171373.PACID_17020 6.7e-159 566.6 Bacteria supH Bacteria COG0561@1,COG0561@2 NA|NA|NA Q phosphatase activity gnl|extdb|FAM19036-p1-1.1_001418 1171373.PACID_17010 7.7e-157 559.7 Propionibacteriales dkgB Bacteria 2GJQ7@201174,4DT39@85009,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family gnl|extdb|FAM19036-p1-1.1_001419 1171373.PACID_17000 1.8e-226 791.6 Actinobacteria 2.8.3.18 ko:K18118 ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R10343 RC00012,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2IAMG@201174,COG0427@1,COG0427@2 NA|NA|NA C acetyl-CoA hydrolase gnl|extdb|FAM19036-p1-1.1_001420 1171373.PACID_16990 1.1e-244 852.0 Propionibacteriales metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 2GKNJ@201174,4DNSW@85009,COG2021@1,COG2021@2 NA|NA|NA E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine gnl|extdb|FAM19036-p1-1.1_001421 1171373.PACID_16980 4.6e-114 417.2 Propionibacteriales metW 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 2IDZY@201174,4DUY7@85009,COG0500@1,COG2226@2 NA|NA|NA Q Methionine biosynthesis protein MetW gnl|extdb|FAM19036-p1-1.1_001424 1171373.PACID_16950 2.6e-146 524.6 Propionibacteriales dpm1 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 2I2FA@201174,4DNYS@85009,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 gnl|extdb|FAM19036-p1-1.1_001425 1171373.PACID_16940 2.3e-56 224.6 Propionibacteriales rbpA GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 2CNY9@1,2IMK6@201174,32SI2@2,4DQUX@85009 NA|NA|NA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters gnl|extdb|FAM19036-p1-1.1_001426 1122997.AUDD01000004_gene1307 1.5e-109 402.5 Propionibacteriales glpQ2 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2GJ5W@201174,4DQB5@85009,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase gnl|extdb|FAM19036-p1-1.1_001427 1171373.PACID_16920 5.5e-137 493.8 Propionibacteriales pdxY GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008478,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042817,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_1723 Bacteria 2HS59@201174,4DNVS@85009,COG2240@1,COG2240@2 NA|NA|NA H Belongs to the pyridoxine kinase family gnl|extdb|FAM19036-p1-1.1_001428 1171373.PACID_16910 1.8e-289 1001.1 Propionibacteriales murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJPW@201174,4DP2I@85009,COG0766@1,COG0766@2 NA|NA|NA M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) gnl|extdb|FAM19036-p1-1.1_001429 1171373.PACID_16890 2e-266 924.5 Propionibacteriales lpdA 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GIXY@201174,4DNBU@85009,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM19036-p1-1.1_001430 1171373.PACID_16880 0.0 1310.8 Propionibacteriales cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K06200 ko00000 Bacteria 2GIYX@201174,4DN9Z@85009,COG1966@1,COG1966@2 NA|NA|NA T 5TM C-terminal transporter carbon starvation CstA gnl|extdb|FAM19036-p1-1.1_001433 1171373.PACID_16830 1.5e-278 964.9 Propionibacteriales ko:K03294 ko00000 2.A.3.2 Bacteria 2GJ75@201174,4DN3R@85009,COG0531@1,COG0531@2 NA|NA|NA E C-terminus of AA_permease gnl|extdb|FAM19036-p1-1.1_001434 1171373.PACID_16820 0.0 1174.5 Actinobacteria Bacteria 2GNW3@201174,COG5498@1,COG5498@2 NA|NA|NA M glycoside hydrolase family 81 gnl|extdb|FAM19036-p1-1.1_001435 1122997.AUDD01000004_gene1300 4.8e-102 377.5 Propionibacteriales bcsA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016020,GO:0016051,GO:0030243,GO:0030244,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:0090540,GO:1901576 2.4.1.12 ko:K00694,ko:K02005,ko:K20541 ko00500,ko01100,ko02026,map00500,map01100,map02026 R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria 2GKFI@201174,4DPBK@85009,COG0845@1,COG0845@2,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family group 2 gnl|extdb|FAM19036-p1-1.1_001436 1171373.PACID_16800 0.0 1111.3 Actinobacteria bcsA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016020,GO:0016051,GO:0030243,GO:0030244,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:0090540,GO:1901576 2.4.1.12 ko:K00694,ko:K20541 ko00500,ko01100,ko02026,map00500,map01100,map02026 R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria 2GKFI@201174,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 gnl|extdb|FAM19036-p1-1.1_001437 1171373.PACID_16790 3.9e-51 207.6 Actinobacteria prfA ko:K02835,ko:K15034 ko00000,ko03012 Bacteria 2I7Z4@201174,COG0216@1,COG0216@2 NA|NA|NA J chain release factor gnl|extdb|FAM19036-p1-1.1_001438 1171373.PACID_16780 9.5e-155 552.7 Propionibacteriales ung GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GK1I@201174,4DNFH@85009,COG1573@1,COG1573@2 NA|NA|NA L Uracil DNA glycosylase superfamily gnl|extdb|FAM19036-p1-1.1_001439 1171373.PACID_16770 3.9e-180 637.5 Propionibacteriales pac ko:K07184 ko00000 Bacteria 2I2N7@201174,4DQ83@85009,COG1938@1,COG1938@2 NA|NA|NA S PAC2 family gnl|extdb|FAM19036-p1-1.1_001440 1171373.PACID_16760 7.9e-277 959.1 Actinobacteria hscA Bacteria 2I90R@201174,COG0443@1,COG0443@2 NA|NA|NA O Belongs to the heat shock protein 70 family gnl|extdb|FAM19036-p1-1.1_001441 1171373.PACID_16750 3.7e-257 893.6 Propionibacteriales ko:K07576 ko00000 Bacteria 2HEXB@201174,4DQ4R@85009,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain gnl|extdb|FAM19036-p1-1.1_001444 1122997.AUDD01000004_gene1293 8.9e-119 433.7 Propionibacteriales ybbD 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM43@201174,4DQDD@85009,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain gnl|extdb|FAM19036-p1-1.1_001445 1171373.PACID_16710 8.6e-154 549.7 Propionibacteriales Bacteria 2GJ3K@201174,4DNXQ@85009,COG1597@1,COG1597@2 NA|NA|NA I diacylglycerol kinase gnl|extdb|FAM19036-p1-1.1_001447 1171373.PACID_16690 4.8e-111 407.1 Propionibacteriales yciO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2GNEW@201174,4DNCR@85009,COG0009@1,COG0009@2 NA|NA|NA J Belongs to the SUA5 family gnl|extdb|FAM19036-p1-1.1_001449 1171373.PACID_16670 2.1e-235 821.2 Propionibacteriales pfp 2.7.1.90 ko:K00895 ko00010,ko00030,ko00051,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map01100,map01110,map01120,map01130 R00764,R02073 RC00017 ko00000,ko00001,ko01000 Bacteria 2GK6W@201174,4DPPT@85009,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions gnl|extdb|FAM19036-p1-1.1_001450 1171373.PACID_16660 1.4e-163 582.4 Propionibacteriales yhjD GO:0003674,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015920,GO:0016020,GO:0016021,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0033036,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1901264,GO:1901505 ko:K07058 ko00000 Bacteria 2GN79@201174,4DS0K@85009,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB gnl|extdb|FAM19036-p1-1.1_001451 1171373.PACID_16650 2.1e-97 361.7 Propionibacteriales merR2 Bacteria 2GM67@201174,4DPQ2@85009,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM19036-p1-1.1_001452 1171373.PACID_16640 9.7e-77 292.7 Propionibacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03617,ko:K08999 ko00000 Bacteria 2GN26@201174,4DQGH@85009,COG1259@1,COG1259@2 NA|NA|NA S Bifunctional nuclease gnl|extdb|FAM19036-p1-1.1_001453 1171373.PACID_16630 6e-123 446.8 Propionibacteriales merR1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 Bacteria 2HBV6@201174,4DQDI@85009,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM19036-p1-1.1_001454 1171373.PACID_16620 1e-85 322.8 Propionibacteriales Bacteria 2GK99@201174,4DR1A@85009,COG1716@1,COG1716@2 NA|NA|NA T zinc-ribbon domain gnl|extdb|FAM19036-p1-1.1_001455 1171373.PACID_16610 1.2e-64 252.3 Bacteria gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 iNJ661.Rv1826 Bacteria COG0509@1,COG0509@2 NA|NA|NA E glycine decarboxylation via glycine cleavage system gnl|extdb|FAM19036-p1-1.1_001456 1171373.PACID_16600 4.3e-127 460.7 Propionibacteriales GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GJ3C@201174,4DR07@85009,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) gnl|extdb|FAM19036-p1-1.1_001457 1171373.PACID_16590 3.9e-43 180.6 Propionibacteriales sbp Bacteria 2IKJW@201174,4DR0I@85009,COG3856@1,COG3856@2 NA|NA|NA S Protein of unknown function (DUF1290) gnl|extdb|FAM19036-p1-1.1_001458 1171373.PACID_16580 4.5e-125 454.1 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GMS5@201174,4DR0G@85009,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) gnl|extdb|FAM19036-p1-1.1_001459 1171373.PACID_16570 8e-109 399.8 Propionibacteriales pgsA GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GM3F@201174,4DQ8M@85009,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family gnl|extdb|FAM19036-p1-1.1_001460 1171373.PACID_16560 1.1e-242 845.5 Propionibacteriales pimA GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 ko:K08256 R11702 ko00000,ko01000,ko01003 GT4 Bacteria 2GKQ8@201174,4DNV1@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM19036-p1-1.1_001461 1171373.PACID_16550 9.4e-169 599.4 Propionibacteriales htrB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 ko:K02517,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2GM7B@201174,4DR30@85009,COG1560@1,COG1560@2 NA|NA|NA M Bacterial lipid A biosynthesis acyltransferase gnl|extdb|FAM19036-p1-1.1_001462 1171373.PACID_16540 3.3e-112 411.0 Propionibacteriales pgsA1 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 ko:K00995,ko:K00999 ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070 R01801,R01802 RC00002,RC00017,RC00078,RC02795 ko00000,ko00001,ko01000 Bacteria 2GYKW@201174,4DP2F@85009,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family gnl|extdb|FAM19036-p1-1.1_001463 1171373.PACID_16530 4.8e-113 413.7 Propionibacteriales hit GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 ko:K19710 ko00230,map00230 R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 Bacteria 2GJT5@201174,4DQ7R@85009,COG0537@1,COG0537@2 NA|NA|NA FG HIT domain gnl|extdb|FAM19036-p1-1.1_001464 1171373.PACID_16520 0.0 1362.8 Propionibacteriales thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GKTC@201174,4DN38@85009,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) gnl|extdb|FAM19036-p1-1.1_001465 1171373.PACID_16510 7.7e-202 709.5 Propionibacteriales adhA 1.1.1.1 ko:K13953,ko:K13979 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 2GNVQ@201174,4DNV3@85009,COG1064@1,COG1064@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM19036-p1-1.1_001466 1121017.AUFG01000023_gene2137 3.4e-75 288.5 Actinobacteria Bacteria 2GMW5@201174,COG4124@1,COG4124@2 NA|NA|NA G Belongs to the glycosyl hydrolase 26 family gnl|extdb|FAM19036-p1-1.1_001467 1287475.HMPREF1650_11685 8.8e-07 60.8 Corynebacteriaceae ylcC 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 22MJ4@1653,2GRRH@201174,COG3764@1,COG3764@2 NA|NA|NA M Sortase (surface protein transpeptidase) gnl|extdb|FAM19036-p1-1.1_001470 1171373.PACID_16440 6.8e-136 490.0 Actinobacteria 3.5.1.104 ko:K22278 ko00000,ko01000 Bacteria 2HEQK@201174,COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase gnl|extdb|FAM19036-p1-1.1_001475 1171373.PACID_16390 7.9e-137 493.0 Bacteria Bacteria COG2138@1,COG2138@2 NA|NA|NA S sirohydrochlorin cobaltochelatase activity gnl|extdb|FAM19036-p1-1.1_001476 1171373.PACID_16380 6.1e-165 586.6 Propionibacteriales 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GKRN@201174,4DNFS@85009,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) gnl|extdb|FAM19036-p1-1.1_001477 1171373.PACID_16370 3.3e-79 300.8 Propionibacteriales msrB 1.8.4.12 ko:K07305 ko00000,ko01000 Bacteria 2IHV0@201174,4DQU8@85009,COG0229@1,COG0229@2 NA|NA|NA O Peptide-methionine (R)-S-oxide reductase gnl|extdb|FAM19036-p1-1.1_001480 1171373.PACID_16340 0.0 1261.5 Propionibacteriales dxs GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_0456,iIT341.HP0354,iJN746.PP_0527 Bacteria 2GMFA@201174,4DNP5@85009,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) gnl|extdb|FAM19036-p1-1.1_001481 1171373.PACID_16330 0.0 1790.4 Propionibacteriales acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJD5@201174,4DPP4@85009,COG1048@1,COG1048@2 NA|NA|NA C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate gnl|extdb|FAM19036-p1-1.1_001482 1171373.PACID_16320 3.4e-35 153.7 Actinobacteria Bacteria 28ZZN@1,2GXJY@201174,2ZMPZ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001483 1171373.PACID_16310 8.6e-226 789.3 Propionibacteriales trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 2GIR3@201174,4DN2V@85009,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family gnl|extdb|FAM19036-p1-1.1_001484 1171373.PACID_16300 0.0 1251.5 Propionibacteriales ydaO Bacteria 2GK5V@201174,4DP47@85009,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM19036-p1-1.1_001485 1171373.PACID_16290 1.6e-123 448.7 Propionibacteriales ceoB ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2GK4N@201174,4DNXX@85009,COG0569@1,COG0569@2 NA|NA|NA P TrkA-N domain gnl|extdb|FAM19036-p1-1.1_001486 1171373.PACID_16280 2.7e-120 438.0 Propionibacteriales trkA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2GKB9@201174,4DN0P@85009,COG0569@1,COG0569@2 NA|NA|NA P TrkA-C domain gnl|extdb|FAM19036-p1-1.1_001487 1171373.PACID_16270 3.2e-65 254.2 Actinobacteria 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IHRX@201174,COG1200@1,COG1200@2 NA|NA|NA KL Nucleic acid binding, OB-fold, tRNA gnl|extdb|FAM19036-p1-1.1_001489 1171373.PACID_16250 1.6e-76 292.0 Propionibacteriales dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IHYY@201174,4DQW7@85009,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA gnl|extdb|FAM19036-p1-1.1_001490 1171373.PACID_16240 3.9e-85 320.9 Propionibacteriales Bacteria 2E4C2@1,2IFS5@201174,32Z7M@2,4DRWV@85009 NA|NA|NA S Protein of unknown function (DUF3093) gnl|extdb|FAM19036-p1-1.1_001491 1171373.PACID_16230 3.8e-41 173.7 Propionibacteriales Bacteria 2DR0Y@1,2GWIF@201174,339QH@2,4DSU4@85009 NA|NA|NA S Protein of unknown function (DUF4235) gnl|extdb|FAM19036-p1-1.1_001492 1171373.PACID_16220 7.9e-48 196.1 Propionibacteriales Bacteria 2ATJW@1,2I810@201174,32RNQ@2,4DR4Y@85009 NA|NA|NA S Domain of unknown function (DUF4193) gnl|extdb|FAM19036-p1-1.1_001493 1171373.PACID_16210 1.6e-192 678.7 Propionibacteriales GO:0008150,GO:0040007 Bacteria 28PUQ@1,2HJT8@201174,2ZCFK@2,4DVN8@85009 NA|NA|NA S Protein of unknown function (DUF3071) gnl|extdb|FAM19036-p1-1.1_001494 1171373.PACID_16200 5e-223 780.0 Propionibacteriales Bacteria 2GISU@201174,4DNS7@85009,COG1524@1,COG1524@2 NA|NA|NA S type I phosphodiesterase nucleotide pyrophosphatase gnl|extdb|FAM19036-p1-1.1_001495 1171373.PACID_16190 5.3e-102 377.1 Propionibacteriales Bacteria 29850@1,2GKR1@201174,2ZVAX@2,4DQC6@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001497 1171373.PACID_16160 2.2e-209 734.6 Propionibacteriales Bacteria 2GKPS@201174,4DRV8@85009,COG4850@1,COG4850@2 NA|NA|NA S Uncharacterized conserved protein (DUF2183) gnl|extdb|FAM19036-p1-1.1_001498 1171373.PACID_16150 0.0 1598.9 Propionibacteriales gyrA GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJ2Q@201174,4DPNM@85009,COG0188@1,COG0188@2 NA|NA|NA L DNA Topoisomerase IV gnl|extdb|FAM19036-p1-1.1_001499 1171373.PACID_16140 3e-68 264.6 Propionibacteriales cah 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 2GM1M@201174,4DQAC@85009,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide gnl|extdb|FAM19036-p1-1.1_001500 1171373.PACID_16130 2.4e-158 565.5 Actinobacteria Bacteria 2DQCH@1,2IEJC@201174,335YP@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001502 1171373.PACID_16110 0.0 1391.3 Propionibacteriales gyrB2 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GM1E@201174,4DN70@85009,COG0187@1,COG0187@2 NA|NA|NA L TopoisomeraseII gnl|extdb|FAM19036-p1-1.1_001503 1171373.PACID_16100 6.4e-30 136.0 Propionibacteriales Bacteria 2E39Y@1,2GQJA@201174,32Y9G@2,4DSBB@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001504 1171373.PACID_16090 7e-98 363.2 Propionibacteriales Bacteria 2I2E3@201174,4DSE0@85009,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_001505 1171373.PACID_16080 2e-205 721.8 Propionibacteriales sigA ko:K03086 ko00000,ko03021 Bacteria 2GK3Z@201174,4DN2F@85009,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth gnl|extdb|FAM19036-p1-1.1_001506 1171373.PACID_16070 7.6e-169 599.7 Propionibacteriales sigA ko:K03086 ko00000,ko03021 Bacteria 2GK3Z@201174,4DNNR@85009,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released gnl|extdb|FAM19036-p1-1.1_001507 1171373.PACID_16060 0.0 2494.2 Propionibacteriales hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 ko00000,ko01000 Bacteria 2GIWX@201174,4DNBR@85009,COG1643@1,COG1643@2 NA|NA|NA L ATP-dependent helicase hrpA gnl|extdb|FAM19036-p1-1.1_001508 1171373.PACID_16050 4.4e-115 420.6 Bacteria Bacteria COG4758@1,COG4758@2 NA|NA|NA KT membrane gnl|extdb|FAM19036-p1-1.1_001509 1171373.PACID_16040 1e-159 569.3 Bacteria GO:0001666,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044464,GO:0050896,GO:0070482,GO:0071944 Bacteria COG0589@1,COG0589@2 NA|NA|NA T AMP binding gnl|extdb|FAM19036-p1-1.1_001510 1171373.PACID_16030 2.5e-172 611.3 Propionibacteriales Bacteria 2EB78@1,2IR56@201174,3357V@2,4DVJ6@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001511 1171373.PACID_16020 4.6e-108 397.1 Propionibacteriales dcd GO:0003674,GO:0003824,GO:0004170,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0033973,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 iPC815.YPO1525 Bacteria 2GKQQ@201174,4DNI0@85009,COG0717@1,COG0717@2 NA|NA|NA F Belongs to the dCTP deaminase family gnl|extdb|FAM19036-p1-1.1_001512 1171373.PACID_16010 0.0 1889.8 Propionibacteriales nrdJ 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2GKX9@201174,4DP4H@85009,COG0209@1,COG0209@2 NA|NA|NA F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen gnl|extdb|FAM19036-p1-1.1_001513 1171373.PACID_16000 6.3e-93 346.7 Propionibacteriales nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 2IHU9@201174,4DQJU@85009,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes gnl|extdb|FAM19036-p1-1.1_001516 1171373.PACID_15960 8.8e-262 909.1 Propionibacteriales hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K03665 ko00000,ko03009 Bacteria 2GK55@201174,4DNPS@85009,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis gnl|extdb|FAM19036-p1-1.1_001517 1171373.PACID_15950 3.9e-145 520.8 Propionibacteriales dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 2GKUD@201174,4DN7Z@85009,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan gnl|extdb|FAM19036-p1-1.1_001518 1171373.PACID_15940 5.2e-170 603.6 Propionibacteriales miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2GKFT@201174,4DP56@85009,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) gnl|extdb|FAM19036-p1-1.1_001519 1171373.PACID_15930 2.2e-09 67.8 Actinobacteria GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 Bacteria 2EJAX@1,2GWPN@201174,33D21@2 NA|NA|NA S MT0933-like antitoxin protein gnl|extdb|FAM19036-p1-1.1_001520 1171373.PACID_15290 9.8e-272 942.2 Propionibacteriales miaB 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2GJEV@201174,4DNBY@85009,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine gnl|extdb|FAM19036-p1-1.1_001521 1171373.PACID_15280 8.4e-181 639.4 Propionibacteriales galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0H@201174,4DP9G@85009,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase gnl|extdb|FAM19036-p1-1.1_001524 1171373.PACID_15250 7.6e-194 682.9 Propionibacteriales recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 2GJ4P@201174,4DPDK@85009,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage gnl|extdb|FAM19036-p1-1.1_001525 1122138.AQUZ01000010_gene5099 6.4e-14 82.8 Propionibacteriales Bacteria 2AU8K@1,2HZCZ@201174,31JVT@2,4DS5N@85009 NA|NA|NA S Protein of unknown function (DUF3046) gnl|extdb|FAM19036-p1-1.1_001527 1171373.PACID_15220 1.2e-37 162.2 Propionibacteriales clgR GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 2GR3F@201174,4DS8T@85009,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM19036-p1-1.1_001528 1171373.PACID_15210 2.8e-79 301.2 Propionibacteriales cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 2IQ8T@201174,4DS1E@85009,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family gnl|extdb|FAM19036-p1-1.1_001529 1171373.PACID_15200 2.6e-106 391.3 Propionibacteriales pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GK5D@201174,4DQPW@85009,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family gnl|extdb|FAM19036-p1-1.1_001531 1171373.PACID_15180 2.9e-153 547.7 Propionibacteriales Bacteria 2GW7W@201174,4DN5P@85009,COG3001@1,COG3001@2 NA|NA|NA G Fructosamine kinase gnl|extdb|FAM19036-p1-1.1_001532 1171373.PACID_15170 5.1e-124 450.3 Actinobacteria Bacteria 2B600@1,2H1C5@201174,31YW8@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001534 1171373.PACID_15150 1.2e-58 232.3 Bacteria Bacteria COG4430@1,COG4430@2 NA|NA|NA F Bacteriocin-protection, YdeI or OmpD-Associated gnl|extdb|FAM19036-p1-1.1_001535 1171373.PACID_15140 6.9e-89 333.2 Propionibacteriales Bacteria 2IQ25@201174,4DW95@85009,COG1708@1,COG1708@2 NA|NA|NA S Uncharacterised protein family (UPF0158) gnl|extdb|FAM19036-p1-1.1_001536 1171373.PACID_15130 2e-115 421.8 Bacteria pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria COG0461@1,COG0461@2 NA|NA|NA F orotate phosphoribosyltransferase activity gnl|extdb|FAM19036-p1-1.1_001537 1171373.PACID_15120 1.2e-123 449.1 Actinobacteria pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 2IPX2@201174,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) gnl|extdb|FAM19036-p1-1.1_001538 1171373.PACID_15110 1.1e-175 622.5 Propionibacteriales pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 2GKC6@201174,4DV5U@85009,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate gnl|extdb|FAM19036-p1-1.1_001539 1171373.PACID_15100 3e-153 547.7 Propionibacteriales pyrK 1.3.1.14,3.5.2.3 ko:K01465,ko:K02823,ko:K05784,ko:K17828 ko00240,ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00240,map00362,map00364,map00622,map01100,map01120,map01220 M00051,M00551 R01869,R01993,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00051,RC00270,RC00632,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17580 Bacteria 2HQ24@201174,4DWEP@85009,COG0543@1,COG0543@2 NA|NA|NA C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) gnl|extdb|FAM19036-p1-1.1_001540 1171373.PACID_15090 0.0 2090.5 Propionibacteriales carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK5N@201174,4DNSQ@85009,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthetase ammonia chain gnl|extdb|FAM19036-p1-1.1_001541 1171373.PACID_15080 3.4e-227 793.9 Propionibacteriales carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 2GKFA@201174,4DNY4@85009,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family gnl|extdb|FAM19036-p1-1.1_001544 1171373.PACID_15050 1.1e-69 269.2 Propionibacteriales yqeY ko:K09117 ko00000 Bacteria 2IFFJ@201174,4DR27@85009,COG1610@1,COG1610@2 NA|NA|NA S Yqey-like protein gnl|extdb|FAM19036-p1-1.1_001545 1171373.PACID_15040 3.9e-195 687.2 Propionibacteriales yghZ ko:K19265 ko00000,ko01000 Bacteria 2GMT5@201174,4DNMA@85009,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM19036-p1-1.1_001547 1171373.PACID_15020 0.0 1882.8 Propionibacteriales aceE GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJRE@201174,4DNUA@85009,COG2609@1,COG2609@2 NA|NA|NA C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) gnl|extdb|FAM19036-p1-1.1_001549 1171373.PACID_15000 2.6e-58 231.1 Actinobacteria Bacteria 2GSU0@201174,COG1433@1,COG1433@2 NA|NA|NA S Dinitrogenase iron-molybdenum cofactor gnl|extdb|FAM19036-p1-1.1_001550 1171373.PACID_14990 8.5e-165 586.3 Propionibacteriales panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 2I3AM@201174,4DUY3@85009,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid gnl|extdb|FAM19036-p1-1.1_001551 1171373.PACID_14980 3.6e-147 527.7 Propionibacteriales fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180,2.3.1.39 ko:K00645,ko:K00648 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082,M00083 R01626,R10707,R11671 RC00004,RC00039,RC02727,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GME0@201174,4DT30@85009,COG0331@1,COG0331@2 NA|NA|NA I Acyl transferase domain gnl|extdb|FAM19036-p1-1.1_001552 1171373.PACID_14970 6.2e-185 653.3 Propionibacteriales fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJP8@201174,4DP78@85009,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids gnl|extdb|FAM19036-p1-1.1_001553 1171373.PACID_14960 2.2e-35 154.5 Propionibacteriales acpP ko:K02078 ko00000,ko00001 Bacteria 2IQ43@201174,4DVYA@85009,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis gnl|extdb|FAM19036-p1-1.1_001554 1171373.PACID_14950 1.5e-239 835.1 Propionibacteriales fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GIY4@201174,4DN2J@85009,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP gnl|extdb|FAM19036-p1-1.1_001555 1171373.PACID_14940 1.8e-95 355.1 Propionibacteriales Bacteria 299E4@1,2GM90@201174,2ZWGX@2,4DQ7U@85009 NA|NA|NA S Protein of unknown function (DUF3145) gnl|extdb|FAM19036-p1-1.1_001556 1171373.PACID_14930 1.1e-124 452.6 Propionibacteriales yggS 2.5.1.3 ko:K00788,ko:K06997 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMRJ@201174,4DQBA@85009,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis gnl|extdb|FAM19036-p1-1.1_001559 1171373.PACID_14900 1.3e-201 708.8 Propionibacteriales Bacteria 2GKSJ@201174,4DQEK@85009,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 gnl|extdb|FAM19036-p1-1.1_001562 1171373.PACID_14870 1.2e-157 562.4 Propionibacteriales Bacteria 2GP42@201174,4DR0A@85009,COG0561@1,COG0561@2 NA|NA|NA J hydrolases of the HAD superfamily gnl|extdb|FAM19036-p1-1.1_001564 1171373.PACID_18700 3.2e-95 354.4 Actinobacteria yqaB Bacteria 2IGK9@201174,COG3981@1,COG3981@2 NA|NA|NA L Gcn5-related n-acetyltransferase gnl|extdb|FAM19036-p1-1.1_001565 1171373.PACID_18690 7.8e-203 713.0 Propionibacteriales ko:K03455 ko00000 2.A.37 Bacteria 2GIRC@201174,4DQ8X@85009,COG0475@1,COG0475@2 NA|NA|NA P Sodium/hydrogen exchanger family gnl|extdb|FAM19036-p1-1.1_001566 1171373.PACID_18680 4.9e-311 1072.8 Actinobacteria Bacteria 2GJ09@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_001568 1171373.PACID_18660 9.6e-187 659.8 Propionibacteriales Bacteria 2GM6E@201174,4DWKP@85009,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase gnl|extdb|FAM19036-p1-1.1_001569 1171373.PACID_18660 7e-56 223.0 Propionibacteriales Bacteria 2GM6E@201174,4DWKP@85009,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase gnl|extdb|FAM19036-p1-1.1_001571 1171373.PACID_18640 5.7e-155 553.5 Propionibacteriales lysG GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003700,GO:0005488,GO:0006275,GO:0006355,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K05596 ko00000,ko03000,ko03036 Bacteria 2GJEC@201174,4DQ1J@85009,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family gnl|extdb|FAM19036-p1-1.1_001573 1171373.PACID_18620 2.2e-105 388.3 Propionibacteriales pdxT GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 iHN637.CLJU_RS19495 Bacteria 2GNYG@201174,4DQFC@85009,COG0311@1,COG0311@2 NA|NA|NA H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS gnl|extdb|FAM19036-p1-1.1_001574 1171373.PACID_18610 2.8e-160 571.2 Propionibacteriales pdxS GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 ko:K06215 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 Bacteria 2GK1T@201174,4DNEB@85009,COG0214@1,COG0214@2 NA|NA|NA H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively gnl|extdb|FAM19036-p1-1.1_001576 1171373.PACID_18590 1.1e-85 322.8 Bacteria Bacteria 2CESX@1,348PT@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001577 1171373.PACID_18580 2e-169 601.7 Actinobacteria cysK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIXE@201174,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family gnl|extdb|FAM19036-p1-1.1_001578 1171373.PACID_18570 1.3e-160 572.4 Propionibacteriales otsB 3.1.3.12 ko:K01087 ko00500,ko01100,map00500,map01100 R02778 RC00017 ko00000,ko00001,ko01000 Bacteria 2GMKW@201174,4DNQI@85009,COG1877@1,COG1877@2 NA|NA|NA G Removes the phosphate from trehalose 6-phosphate to produce free trehalose gnl|extdb|FAM19036-p1-1.1_001579 1171373.PACID_18560 8.7e-270 935.6 Propionibacteriales otsA GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K16055 ko00500,ko01100,map00500,map01100 R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT20 Bacteria 2GMX7@201174,4DNDY@85009,COG0380@1,COG0380@2 NA|NA|NA G Glycosyltransferase family 20 gnl|extdb|FAM19036-p1-1.1_001580 1171373.PACID_18550 7e-287 992.6 Propionibacteriales ydiF Bacteria 2GJHN@201174,4DPS7@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM19036-p1-1.1_001583 1171373.PACID_18530 1.4e-95 355.5 Bacteria Bacteria 2EFFR@1,3398G@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001584 1171373.PACID_18520 1.1e-102 379.4 Bacteria ko:K03086,ko:K03087,ko:K03093 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria COG0568@1,COG0568@2 NA|NA|NA K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released gnl|extdb|FAM19036-p1-1.1_001585 1171373.PACID_18510 0.0 1173.7 Propionibacteriales dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFX@201174,4DN6K@85009,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication gnl|extdb|FAM19036-p1-1.1_001586 1171373.PACID_18500 6.2e-210 736.5 Actinobacteria dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 Bacteria 2GJ8F@201174,COG0232@1,COG0232@2 NA|NA|NA F Deoxyguanosinetriphosphate triphosphohydrolase-like protein gnl|extdb|FAM19036-p1-1.1_001590 1171373.PACID_26740 2.3e-221 775.0 Propionibacteriales Bacteria 2GU7G@201174,4DQSY@85009,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases gnl|extdb|FAM19036-p1-1.1_001591 1171373.PACID_18420 5.2e-144 516.9 Propionibacteriales sdhB 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJPS@201174,4DPU6@85009,COG0479@1,COG0479@2 NA|NA|NA C Succinate dehydrogenase fumarate reductase gnl|extdb|FAM19036-p1-1.1_001593 1171373.PACID_18400 2.2e-137 495.0 Propionibacteriales sdhC_1 ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 28HIR@1,2I860@201174,30UAY@2,4DWJ7@85009 NA|NA|NA C succinate dehydrogenase gnl|extdb|FAM19036-p1-1.1_001594 1171373.PACID_18390 4e-283 979.9 Propionibacteriales gadB 4.1.1.15 ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 M00027 R00261,R00489,R01682,R02466 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKIH@201174,4DPUT@85009,COG0076@1,COG0076@2 NA|NA|NA E Pyridoxal-dependent decarboxylase conserved domain gnl|extdb|FAM19036-p1-1.1_001595 1171373.PACID_18380 8.5e-128 463.0 Actinobacteria 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2GNMT@201174,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F nicotinate-nucleotide adenylyltransferase activity gnl|extdb|FAM19036-p1-1.1_001596 1171373.PACID_18370 2.1e-196 691.4 Propionibacteriales nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS12020 Bacteria 2GM59@201174,4DNNM@85009,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate gnl|extdb|FAM19036-p1-1.1_001597 1171373.PACID_18360 0.0 1077.4 Propionibacteriales nadB GO:0008150,GO:0040007 1.3.5.4,1.4.3.16 ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1595 Bacteria 2I2IJ@201174,4DN9N@85009,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate gnl|extdb|FAM19036-p1-1.1_001599 1171373.PACID_18340 6.1e-287 992.6 Propionibacteriales glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria 2GIT3@201174,4DPNB@85009,COG0423@1,COG0423@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family gnl|extdb|FAM19036-p1-1.1_001600 1171373.PACID_18330 1.5e-52 211.8 Bacteria Bacteria COG2329@1,COG2329@2 NA|NA|NA S heme oxygenase (decyclizing) activity gnl|extdb|FAM19036-p1-1.1_001601 1171373.PACID_18320 1.2e-73 282.3 Propionibacteriales zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711,ko:K09823 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 2IKS3@201174,4DQZK@85009,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family gnl|extdb|FAM19036-p1-1.1_001602 1400520.LFAB_15560 4.8e-47 194.9 Lactobacillaceae Bacteria 1UPXV@1239,2EH72@1,33AYW@2,3F95D@33958,4HY5A@91061 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001608 1171373.PACID_14480 0.0 1252.3 Actinobacteria ohyA GO:0000166,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0010033,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0033993,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0050896,GO:0070542,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901700 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 2GKZ8@201174,COG4716@1,COG4716@2 NA|NA|NA S MCRA family gnl|extdb|FAM19036-p1-1.1_001609 1171373.PACID_14470 3.4e-153 547.7 Actinobacteria Bacteria 2GIS3@201174,COG0604@1,COG0604@2 NA|NA|NA C alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_001610 1171373.PACID_14460 2.2e-139 501.5 Propionibacteriales recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GK81@201174,4DP6A@85009,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination gnl|extdb|FAM19036-p1-1.1_001611 1171373.PACID_14450 0.0 1676.4 Propionibacteriales vpr GO:0005575,GO:0005576 ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 2GK3D@201174,4DTXD@85009,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family gnl|extdb|FAM19036-p1-1.1_001612 1171373.PACID_14440 9.8e-111 406.0 Actinobacteria Bacteria 2GY1D@201174,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family gnl|extdb|FAM19036-p1-1.1_001613 1122997.AUDD01000014_gene1449 1.1e-144 519.2 Propionibacteriales uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2GIXF@201174,4DPW4@85009,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids gnl|extdb|FAM19036-p1-1.1_001614 1171373.PACID_14420 2e-157 561.6 Propionibacteriales Bacteria 2HQD2@201174,4DVEM@85009,COG0121@1,COG0121@2 NA|NA|NA S Glutamine amidotransferases class-II gnl|extdb|FAM19036-p1-1.1_001615 1171373.PACID_14410 6.8e-135 486.9 Propionibacteriales ko:K02029,ko:K10007 ko02010,map02010 M00233,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GNBH@201174,4DQVW@85009,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001616 1171373.PACID_14400 2.6e-107 394.8 Propionibacteriales glnM GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GNUR@201174,4DR1N@85009,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001617 1171373.PACID_14390 5.3e-170 603.6 Actinobacteria ko:K10005 ko02010,map02010 M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 Bacteria 2GJH8@201174,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family gnl|extdb|FAM19036-p1-1.1_001618 1171373.PACID_14380 0.0 1179.9 Propionibacteriales leuA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GISX@201174,4DMZU@85009,COG0119@1,COG0119@2 NA|NA|NA E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) gnl|extdb|FAM19036-p1-1.1_001620 1171373.PACID_14350 7e-195 686.4 Propionibacteriales era GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043021,GO:0043024,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070181,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:1901363 ko:K03595 ko00000,ko03009,ko03029 Bacteria 2GJJE@201174,4DNEH@85009,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism gnl|extdb|FAM19036-p1-1.1_001621 1171373.PACID_14340 2.1e-233 814.7 Propionibacteriales corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GIWR@201174,4DNND@85009,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain gnl|extdb|FAM19036-p1-1.1_001622 1171373.PACID_14330 1.1e-83 315.8 Propionibacteriales ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2GMUF@201174,4DQJA@85009,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA gnl|extdb|FAM19036-p1-1.1_001623 1171373.PACID_14310 1.6e-200 705.3 Propionibacteriales phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 2GK0W@201174,4DPI2@85009,COG1702@1,COG1702@2 NA|NA|NA T PhoH-like protein gnl|extdb|FAM19036-p1-1.1_001624 1171373.PACID_14320 3.3e-203 714.1 Propionibacteriales 2.7.1.89 ko:K07251 ko00730,ko01100,map00730,map01100 R02134 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2I1JS@201174,4DSVT@85009,COG0510@1,COG0510@2 NA|NA|NA M thiamine kinase activity gnl|extdb|FAM19036-p1-1.1_001625 1171373.PACID_14300 1e-53 215.7 Actinobacteria Bacteria 2CH19@1,2IRW2@201174,33DEK@2 NA|NA|NA S Immunity protein 51 gnl|extdb|FAM19036-p1-1.1_001626 1171373.PACID_14290 1.3e-105 389.0 Bacteria yafE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase gnl|extdb|FAM19036-p1-1.1_001628 1171373.PACID_14270 1.6e-106 392.1 Bacteria ybzH Bacteria COG0640@1,COG0640@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM19036-p1-1.1_001629 1171373.PACID_14260 7.1e-189 666.4 Propionibacteriales pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 2GNBX@201174,4DQ1B@85009,COG0596@1,COG0596@2 NA|NA|NA S Belongs to the peptidase S33 family gnl|extdb|FAM19036-p1-1.1_001630 1171373.PACID_14250 8.5e-128 463.0 Actinobacteria yhhQ ko:K09125 ko00000 Bacteria 2IFDB@201174,COG1738@1,COG1738@2 NA|NA|NA S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage gnl|extdb|FAM19036-p1-1.1_001632 1171373.PACID_14230 1.2e-64 252.3 Actinobacteria Bacteria 2GUMH@201174,COG5611@1,COG5611@2 NA|NA|NA S PIN domain gnl|extdb|FAM19036-p1-1.1_001633 1171373.PACID_14220 4.7e-211 740.3 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I9MY@201174,4DQIN@85009,COG1668@1,COG1668@2 NA|NA|NA CP ABC-2 family transporter protein gnl|extdb|FAM19036-p1-1.1_001634 1171373.PACID_14210 1.1e-167 595.9 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I2DK@201174,4DP66@85009,COG4152@1,COG4152@2 NA|NA|NA S ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_001635 1171373.PACID_14200 2.3e-111 408.3 Propionibacteriales Bacteria 2GJ46@201174,4DQGA@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_001636 1171373.PACID_14190 1.3e-225 788.9 Propionibacteriales Bacteria 2GJEG@201174,4DRHK@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_001637 1171373.PACID_14180 6.7e-245 852.8 Actinobacteria tgt 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 2GMWY@201174,COG0343@1,COG0343@2 NA|NA|NA J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) gnl|extdb|FAM19036-p1-1.1_001638 1171373.PACID_14170 3.4e-158 564.3 Propionibacteriales rhtA_1 ko:K11939 ko00000,ko02000 2.A.7.3.6 Bacteria 2GJKB@201174,4DQPD@85009,COG5006@1,COG5006@2 NA|NA|NA S EamA-like transporter family gnl|extdb|FAM19036-p1-1.1_001639 1171373.PACID_14160 1.8e-210 738.4 Actinobacteria 2.3.1.209,2.7.7.23,2.7.7.83 ko:K00972,ko:K21379 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00361,M00362 R00416 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2H30P@201174,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain gnl|extdb|FAM19036-p1-1.1_001640 1171373.PACID_14150 0.0 1391.7 Propionibacteriales recQ 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJSS@201174,4DNK3@85009,COG0514@1,COG0514@2,COG1040@1,COG1040@2 NA|NA|NA L Type III restriction enzyme, res subunit gnl|extdb|FAM19036-p1-1.1_001641 1171373.PACID_14140 1.5e-65 255.4 Actinobacteria ko:K15977 ko00000 Bacteria 2GUAH@201174,COG2259@1,COG2259@2 NA|NA|NA S DoxX gnl|extdb|FAM19036-p1-1.1_001642 1171373.PACID_14130 0.0 1166.8 Propionibacteriales mtlA 2.7.1.197,2.7.1.202 ko:K02768,ko:K02798,ko:K02799,ko:K02800,ko:K11183 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273,M00274 R02704,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 Bacteria 2GMYR@201174,4DPTM@85009,COG2213@1,COG2213@2,COG4668@1,COG4668@2 NA|NA|NA G Phosphotransferase system, EIIC gnl|extdb|FAM19036-p1-1.1_001643 1171373.PACID_14120 8.4e-201 706.1 Propionibacteriales 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC7@201174,4DT4V@85009,COG1063@1,COG1063@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM19036-p1-1.1_001644 1171373.PACID_14110 1.7e-123 448.7 Propionibacteriales rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 1.13.12.16,2.1.1.193 ko:K00459,ko:K09761 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000,ko03009 Bacteria 2GTKX@201174,4DQEM@85009,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit gnl|extdb|FAM19036-p1-1.1_001645 1171373.PACID_14100 1.7e-210 738.4 Propionibacteriales dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03686 ko00000,ko03029,ko03110 Bacteria 2GK69@201174,4DPD2@85009,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins gnl|extdb|FAM19036-p1-1.1_001646 1171373.PACID_14090 5.5e-181 640.2 Propionibacteriales hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 2GKF5@201174,4DP2Y@85009,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons gnl|extdb|FAM19036-p1-1.1_001647 1171373.PACID_14080 1.2e-151 542.3 Actinobacteria blaB3 Bacteria 2GMHY@201174,COG0491@1,COG0491@2 NA|NA|NA S beta-lactamase domain protein gnl|extdb|FAM19036-p1-1.1_001649 1121272.KB903249_gene1698 1.3e-19 104.4 Micromonosporales Bacteria 29WDW@1,2I444@201174,30HZK@2,4DKEH@85008 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001650 1122997.AUDD01000014_gene1473 3e-158 564.3 Propionibacteriales suhB2 3.1.3.25,3.1.3.7 ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 M00131 R00188,R00508,R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GP74@201174,4DQB7@85009,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family gnl|extdb|FAM19036-p1-1.1_001651 1171373.PACID_14050 4.6e-157 560.5 Propionibacteriales trpH GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0097657,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 2GIZ5@201174,4DN6Z@85009,COG0613@1,COG0613@2 NA|NA|NA S Protein of unknown function (DUF3097) gnl|extdb|FAM19036-p1-1.1_001652 1171373.PACID_14040 1.2e-219 768.8 Propionibacteriales hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 2GJXX@201174,4DN32@85009,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound gnl|extdb|FAM19036-p1-1.1_001653 1171373.PACID_14030 8.1e-222 776.2 Propionibacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GMUM@201174,4DQ1V@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_001655 1171373.PACID_14010 7e-153 546.6 Propionibacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GK1V@201174,4DQI4@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001657 1171373.PACID_13990 7.7e-247 859.4 Propionibacteriales ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,4DPNV@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM19036-p1-1.1_001658 1171373.PACID_13980 6.8e-113 413.3 Propionibacteriales Bacteria 2HD07@201174,4DSG2@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_001659 1171373.PACID_13970 1.2e-166 592.4 Propionibacteriales yjjC ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKEH@201174,4DPD1@85009,COG1131@1,COG1131@2 NA|NA|NA V PFAM ABC transporter related gnl|extdb|FAM19036-p1-1.1_001660 1171373.PACID_13960 7.8e-291 1005.7 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMSI@201174,4DPHI@85009,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide gnl|extdb|FAM19036-p1-1.1_001661 1171373.PACID_13950 0.0 1301.6 Propionibacteriales acs 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJCG@201174,4DPMA@85009,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA gnl|extdb|FAM19036-p1-1.1_001662 1171373.PACID_13940 0.0 1309.7 Propionibacteriales acs 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJCG@201174,4DPMA@85009,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA gnl|extdb|FAM19036-p1-1.1_001664 1171373.PACID_13920 2.6e-188 664.5 Propionibacteriales menB GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK5G@201174,4DNED@85009,COG0447@1,COG0447@2 NA|NA|NA H Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily gnl|extdb|FAM19036-p1-1.1_001666 1171373.PACID_13900 3.7e-232 810.4 Propionibacteriales menF 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKE8@201174,4DPGF@85009,COG1169@1,COG1169@2 NA|NA|NA HQ Isochorismate synthase gnl|extdb|FAM19036-p1-1.1_001669 1171373.PACID_13870 4.9e-94 350.5 Propionibacteriales 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2IFHQ@201174,4DTIP@85009,COG0174@1,COG0174@2 NA|NA|NA E DinB superfamily gnl|extdb|FAM19036-p1-1.1_001670 1171373.PACID_13860 1.1e-85 322.4 Propionibacteriales Bacteria 2IFMD@201174,4DQC3@85009,COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity gnl|extdb|FAM19036-p1-1.1_001671 1171373.PACID_13850 3e-27 127.1 Bacteria ko:K07746 ko00000,ko02048 Bacteria COG3609@1,COG3609@2 NA|NA|NA K positive regulation of growth gnl|extdb|FAM19036-p1-1.1_001675 1171373.PACID_13820 3.7e-36 157.1 Propionibacteriales rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ73@201174,4DS53@85009,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA gnl|extdb|FAM19036-p1-1.1_001677 1171373.PACID_13800 3.3e-303 1047.0 Propionibacteriales sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03086 ko00000,ko03021 Bacteria 2GIU5@201174,4DP3W@85009,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit gnl|extdb|FAM19036-p1-1.1_001678 1171373.PACID_13790 0.0 1402.1 Propionibacteriales comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2GJGR@201174,4DP9N@85009,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein gnl|extdb|FAM19036-p1-1.1_001680 1171373.PACID_13770 0.0 1693.7 Propionibacteriales leuS 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJI1@201174,4DNGN@85009,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family gnl|extdb|FAM19036-p1-1.1_001681 1122998.AUHZ01000020_gene1727 3.8e-79 302.0 Propionibacteriales Bacteria 2AR9G@1,2GN9V@201174,31GJC@2,4DRVD@85009 NA|NA|NA S Domain of unknown function (DUF4192) gnl|extdb|FAM19036-p1-1.1_001683 1171373.PACID_13740 1.4e-130 472.2 Propionibacteriales frnE 5.3.4.1 ko:K01829 ko00000,ko01000 Bacteria 2GNBC@201174,4DQ7I@85009,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain gnl|extdb|FAM19036-p1-1.1_001684 1035308.AQYY01000002_gene409 1.1e-157 562.8 Peptococcaceae 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,24AY7@186801,261CX@186807,COG1063@1,COG1063@2 NA|NA|NA E PFAM Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM19036-p1-1.1_001685 1171373.PACID_13720 1.9e-89 335.1 Propionibacteriales guaD 3.5.4.3,3.5.4.33 ko:K01487,ko:K11991 ko00230,ko01100,map00230,map01100 R01676,R10223 RC00204,RC00477 ko00000,ko00001,ko01000,ko03016 Bacteria 2INAI@201174,4DQQ8@85009,COG0590@1,COG0590@2 NA|NA|NA FJ MafB19-like deaminase gnl|extdb|FAM19036-p1-1.1_001686 1171373.PACID_13710 5.7e-69 266.9 Actinobacteria Bacteria 2E7J0@1,2GTP6@201174,33219@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001687 1171373.PACID_13700 2.1e-100 371.7 Propionibacteriales Bacteria 2GJHD@201174,4DQB9@85009,COG1309@1,COG1309@2 NA|NA|NA K PFAM regulatory protein TetR gnl|extdb|FAM19036-p1-1.1_001688 1171373.PACID_13690 4.2e-261 906.7 Propionibacteriales ko:K07039,ko:K09858 ko00000 Bacteria 2GMVI@201174,4DSJP@85009,COG3012@1,COG3012@2 NA|NA|NA S Plasmid pRiA4b ORF-3-like protein gnl|extdb|FAM19036-p1-1.1_001689 1171373.PACID_13680 1.5e-166 592.0 Actinobacteria Bacteria 2GIZE@201174,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM19036-p1-1.1_001690 1171373.PACID_13670 8e-182 642.9 Actinobacteria Bacteria 2BVU5@1,2HZF5@201174,2Z9FH@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001691 1171373.PACID_13660 6.8e-270 936.0 Actinobacteria purA1 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 2HNV8@201174,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP gnl|extdb|FAM19036-p1-1.1_001692 1171373.PACID_13650 5e-100 370.5 Actinobacteria 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2IDV8@201174,COG1051@1,COG1051@2 NA|NA|NA F belongs to the nudix hydrolase family gnl|extdb|FAM19036-p1-1.1_001694 525309.HMPREF0494_0063 1e-38 166.4 Lactobacillaceae Bacteria 1U7EZ@1239,2AGDM@1,316JD@2,3F9I6@33958,4IHAX@91061 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001696 1171373.PACID_13610 6.9e-126 456.8 Bacteria ko:K07506 ko00000,ko03000 Bacteria COG4977@1,COG4977@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM19036-p1-1.1_001698 1171373.PACID_13580 1.4e-185 655.6 Actinobacteria Bacteria 29AVK@1,2H334@201174,2ZXUS@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001699 1171373.PACID_13570 1.9e-74 285.0 Propionibacteriales ko:K07032 ko00000 Bacteria 2IMDZ@201174,4DSXA@85009,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gnl|extdb|FAM19036-p1-1.1_001700 1171373.PACID_13560 1.5e-294 1018.1 Propionibacteriales ydiF Bacteria 2GJHN@201174,4DPS7@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM19036-p1-1.1_001701 1171373.PACID_13550 1.1e-59 235.7 Propionibacteriales Bacteria 2IKPX@201174,4DRBT@85009,COG4898@1,COG4898@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2200) gnl|extdb|FAM19036-p1-1.1_001703 1171373.PACID_13530 6.6e-57 226.5 Propionibacteriales ko:K07343 ko00000 Bacteria 2IKKV@201174,4DSB4@85009,COG3070@1,COG3070@2 NA|NA|NA K TfoX N-terminal domain gnl|extdb|FAM19036-p1-1.1_001704 1171373.PACID_13520 8.4e-37 159.1 Actinobacteria Bacteria 2DD8U@1,2GZ7Z@201174,2ZH36@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001705 1171373.PACID_13510 3.8e-41 173.7 Actinobacteria Bacteria 2ESE5@1,2IS59@201174,33JYU@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001707 1171373.PACID_13480 5.7e-77 293.5 Propionibacteriales lrp ko:K03719 ko00000,ko03000,ko03036 Bacteria 2IG2K@201174,4DS0H@85009,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type gnl|extdb|FAM19036-p1-1.1_001708 1171373.PACID_13470 8.6e-108 396.4 Propionibacteriales Bacteria 2GNNU@201174,4DVAY@85009,COG1280@1,COG1280@2 NA|NA|NA E LysE type translocator gnl|extdb|FAM19036-p1-1.1_001711 1043205.AFYF01000024_gene556 4.1e-14 83.6 Intrasporangiaceae Bacteria 2II0A@201174,4FGIY@85021,COG1247@1,COG1247@2 NA|NA|NA M -acetyltransferase gnl|extdb|FAM19036-p1-1.1_001713 1121353.H924_12870 6.2e-113 413.7 Corynebacteriaceae ko:K02315 ko00000,ko03032 Bacteria 22MBX@1653,2IA1S@201174,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein gnl|extdb|FAM19036-p1-1.1_001714 1121353.H924_12865 2.6e-222 778.1 Corynebacteriaceae Bacteria 22KVX@1653,2GM4J@201174,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM19036-p1-1.1_001716 1209984.BN978_05393 9e-113 413.7 Mycobacteriaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2398X@1762,2IEZB@201174,COG0210@1,COG0210@2 NA|NA|NA L DNA helicase gnl|extdb|FAM19036-p1-1.1_001717 1209984.BN978_05394 3.5e-182 644.8 Mycobacteriaceae ko:K07459 ko00000 Bacteria 2365M@1762,2IAVY@201174,COG3950@1,COG3950@2 NA|NA|NA L AAA ATPase domain gnl|extdb|FAM19036-p1-1.1_001718 1224164.B843_03665 0.0 1339.7 Corynebacteriaceae 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 22M6R@1653,2I8IG@201174,COG1061@1,COG1061@2 NA|NA|NA KL protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_001719 504474.cu1796 1.2e-264 919.1 Corynebacteriaceae modA 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 22MHD@1653,2I8FH@201174,COG2189@1,COG2189@2 NA|NA|NA L Adenine specific DNA methylase Mod gnl|extdb|FAM19036-p1-1.1_001720 1463900.JOIX01000005_gene1114 9.1e-11 73.9 Actinobacteria Bacteria 2HX7D@201174,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_001725 1171373.PACID_13390 6.3e-64 250.0 Propionibacteriales rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2IKZ3@201174,4DR96@85009,COG0799@1,COG0799@2 NA|NA|NA S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation gnl|extdb|FAM19036-p1-1.1_001727 1171373.PACID_13360 3.3e-220 770.8 Propionibacteriales proA GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0293,iNJ661.Rv2427c,iYO844.BSU13130 Bacteria 2GISA@201174,4DNEG@85009,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate gnl|extdb|FAM19036-p1-1.1_001728 1171373.PACID_13350 1.8e-212 745.0 Propionibacteriales proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM8U@201174,4DNUG@85009,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate gnl|extdb|FAM19036-p1-1.1_001729 1171373.PACID_13340 6.1e-285 986.1 Propionibacteriales obg GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 ko:K03979 ko00000,ko01000,ko03009 Bacteria 2GISB@201174,4DNZK@85009,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control gnl|extdb|FAM19036-p1-1.1_001731 1171373.PACID_13320 3.5e-42 177.2 Propionibacteriales rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQDI@201174,4DRNG@85009,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family gnl|extdb|FAM19036-p1-1.1_001732 1122997.AUDD01000009_gene257 1.3e-45 188.7 Propionibacteriales rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ9A@201174,4DRJ6@85009,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 gnl|extdb|FAM19036-p1-1.1_001733 1171373.PACID_13300 1.1e-292 1012.7 Propionibacteriales rne GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2GMM5@201174,4DPJ7@85009,COG1530@1,COG1530@2 NA|NA|NA J Ribonuclease E/G family gnl|extdb|FAM19036-p1-1.1_001735 1171373.PACID_13280 1e-301 1042.0 Propionibacteriales nagA 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM43@201174,4DNRP@85009,COG1472@1,COG1472@2 NA|NA|NA G PFAM glycoside hydrolase, family 3 domain protein gnl|extdb|FAM19036-p1-1.1_001736 1171373.PACID_13270 0.0 1354.0 Propionibacteriales Bacteria 2GJY1@201174,4DNWJ@85009,COG1032@1,COG1032@2 NA|NA|NA C Elongator protein 3, MiaB family, Radical SAM gnl|extdb|FAM19036-p1-1.1_001737 1171373.PACID_13260 4.6e-76 290.4 Propionibacteriales ndk 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 2IFBU@201174,4DQR5@85009,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate gnl|extdb|FAM19036-p1-1.1_001738 1171373.PACID_13250 2.1e-55 221.5 Propionibacteriales Bacteria 2E69F@1,2I8BN@201174,330XE@2,4DSB3@85009 NA|NA|NA S Protein of unknown function (DUF4233) gnl|extdb|FAM19036-p1-1.1_001739 1171373.PACID_13240 8.6e-276 955.7 Propionibacteriales folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJP2@201174,4DNMV@85009,COG0285@1,COG0285@2 NA|NA|NA H Mur ligase middle domain gnl|extdb|FAM19036-p1-1.1_001740 1171373.PACID_13230 4.9e-60 236.9 Propionibacteriales rbpA Bacteria 2CNY9@1,2IKKZ@201174,31GEE@2,4DQSD@85009 NA|NA|NA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters gnl|extdb|FAM19036-p1-1.1_001742 1171373.PACID_13210 4.2e-141 507.3 Propionibacteriales tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXZ@201174,4DP7B@85009,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) gnl|extdb|FAM19036-p1-1.1_001743 1171373.PACID_13200 2.2e-221 774.6 Propionibacteriales pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJC6@201174,4DNJD@85009,COG0126@1,COG0126@2 NA|NA|NA G Belongs to the phosphoglycerate kinase family gnl|extdb|FAM19036-p1-1.1_001744 1171373.PACID_13190 5.4e-189 666.8 Propionibacteriales gap 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJK4@201174,4DNQ8@85009,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gnl|extdb|FAM19036-p1-1.1_001745 1171373.PACID_13180 1.1e-175 622.5 Propionibacteriales whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 ko:K09762 ko00000 Bacteria 2GJZU@201174,4DNGS@85009,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation gnl|extdb|FAM19036-p1-1.1_001747 1171373.PACID_13160 5.1e-159 567.0 Propionibacteriales rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 2GMWB@201174,4DPVQ@85009,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities gnl|extdb|FAM19036-p1-1.1_001748 1171373.PACID_13150 0.0 1345.9 Propionibacteriales uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GIS4@201174,4DN4X@85009,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gnl|extdb|FAM19036-p1-1.1_001749 1171373.PACID_13140 6.4e-142 510.0 Bacteria 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria COG0406@1,COG0406@2 NA|NA|NA G alpha-ribazole phosphatase activity gnl|extdb|FAM19036-p1-1.1_001750 1171373.PACID_13130 2.5e-68 264.6 Actinobacteria Bacteria 2IKSY@201174,COG2146@1,COG2146@2 NA|NA|NA P Rieske 2Fe-2S gnl|extdb|FAM19036-p1-1.1_001751 1171373.PACID_13120 1.1e-54 219.2 Propionibacteriales Bacteria 2E89B@1,2I0A6@201174,332N6@2,4DSMD@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001752 1171373.PACID_13110 0.0 1983.4 Propionibacteriales uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJUV@201174,4DN4J@85009,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate gnl|extdb|FAM19036-p1-1.1_001754 1171373.PACID_13090 1e-163 582.8 Propionibacteriales terC ko:K05794 ko00000 Bacteria 2GIWU@201174,4DNU5@85009,COG0861@1,COG0861@2 NA|NA|NA P Membrane protein TerC gnl|extdb|FAM19036-p1-1.1_001755 1171373.PACID_13080 0.0 1261.9 Propionibacteriales uvrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJ03@201174,4DN5W@85009,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage gnl|extdb|FAM19036-p1-1.1_001758 1171373.PACID_13040 2e-240 838.2 Propionibacteriales rpsA ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJAK@201174,4DPIM@85009,COG0539@1,COG0539@2 NA|NA|NA J ribosomal protein gnl|extdb|FAM19036-p1-1.1_001759 1171373.PACID_13030 5.4e-122 443.7 Propionibacteriales ylcC 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GPPJ@201174,4DSRG@85009,COG3764@1,COG3764@2 NA|NA|NA M Sortase (surface protein transpeptidase) gnl|extdb|FAM19036-p1-1.1_001761 1171373.PACID_13020 1.7e-122 445.3 Actinobacteria dld ko:K18930 ko00000 Bacteria 2GKI9@201174,COG0247@1,COG0247@2,COG0277@1,COG0277@2,COG0479@1,COG0479@2 NA|NA|NA C FAD linked oxidase gnl|extdb|FAM19036-p1-1.1_001762 1171373.PACID_13010 0.0 1732.2 Propionibacteriales polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJY2@201174,4DNJG@85009,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity gnl|extdb|FAM19036-p1-1.1_001763 1171373.PACID_13000 5e-139 500.4 Propionibacteriales cobF 2.1.1.130,2.1.1.151,2.1.1.152 ko:K02228,ko:K03394 ko00860,ko01100,map00860,map01100 R03948,R05219,R05808 RC00003,RC00923,RC01035,RC01662,RC02890 ko00000,ko00001,ko01000 Bacteria 2GJFA@201174,4DNC4@85009,COG2243@1,COG2243@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases gnl|extdb|FAM19036-p1-1.1_001764 1171373.PACID_12990 1.6e-73 282.0 Bacteria ydiI Bacteria COG2050@1,COG2050@2 NA|NA|NA Q thiolester hydrolase activity gnl|extdb|FAM19036-p1-1.1_001765 1171373.PACID_12980 3.6e-96 357.8 Propionibacteriales pdtaR GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 ko:K22010 M00839 ko00000,ko00002,ko02022 Bacteria 2GK7T@201174,4DNU7@85009,COG3707@1,COG3707@2 NA|NA|NA T ANTAR gnl|extdb|FAM19036-p1-1.1_001767 1171373.PACID_12960 8e-271 939.1 Propionibacteriales pyk GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 Bacteria 2GJY8@201174,4DPR2@85009,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family gnl|extdb|FAM19036-p1-1.1_001768 1171373.PACID_12950 6.9e-178 629.8 Propionibacteriales rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 2GIY1@201174,4DN88@85009,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil gnl|extdb|FAM19036-p1-1.1_001770 1171373.PACID_12930 2.7e-73 281.2 Propionibacteriales dksA ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 2GJBE@201174,4DR4Q@85009,COG1734@1,COG1734@2 NA|NA|NA T Prokaryotic dksA/traR C4-type zinc finger gnl|extdb|FAM19036-p1-1.1_001771 1171373.PACID_12920 1e-68 267.3 Bacteria wag31 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 Bacteria COG3599@1,COG3599@2 NA|NA|NA D regulation of cell shape gnl|extdb|FAM19036-p1-1.1_001772 1171373.PACID_12910 2e-43 181.4 Bacteria yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria COG0762@1,COG0762@2 NA|NA|NA D integral membrane protein gnl|extdb|FAM19036-p1-1.1_001773 1171373.PACID_12900 5.3e-98 363.6 Propionibacteriales sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 2GNVH@201174,4DR13@85009,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA gnl|extdb|FAM19036-p1-1.1_001774 1171373.PACID_12890 4.4e-146 523.9 Propionibacteriales yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 2GN1M@201174,4DR2J@85009,COG1496@1,COG1496@2 NA|NA|NA S Multi-copper polyphenol oxidoreductase laccase gnl|extdb|FAM19036-p1-1.1_001775 1171373.PACID_12880 1e-194 686.0 Propionibacteriales ftsZ GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 2GJWC@201174,4DND0@85009,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity gnl|extdb|FAM19036-p1-1.1_001776 1171373.PACID_12870 6.7e-109 400.2 Propionibacteriales ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 ko:K01921,ko:K03589,ko:K06438 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 2H4A4@201174,4DRPK@85009,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein FtsQ gnl|extdb|FAM19036-p1-1.1_001777 1171373.PACID_12860 4.6e-274 949.9 Propionibacteriales murC GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2I2E7@201174,4DNNN@85009,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family gnl|extdb|FAM19036-p1-1.1_001778 1171373.PACID_12850 8.3e-210 736.1 Propionibacteriales murG 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232 Bacteria 2GJEM@201174,4DN0T@85009,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) gnl|extdb|FAM19036-p1-1.1_001780 1171373.PACID_12830 2.5e-283 980.7 Propionibacteriales murD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2155c Bacteria 2GJZA@201174,4DNTV@85009,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) gnl|extdb|FAM19036-p1-1.1_001781 1171373.PACID_12820 4.2e-200 703.7 Propionibacteriales mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 2GNEH@201174,4DNZ9@85009,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gnl|extdb|FAM19036-p1-1.1_001782 1171373.PACID_12810 4.2e-267 926.8 Propionibacteriales murF 4.99.1.1,4.99.1.9,6.3.2.10 ko:K01772,ko:K01929 ko00300,ko00550,ko00860,ko01100,ko01110,ko01502,map00300,map00550,map00860,map01100,map01110,map01502 M00121 R00310,R04573,R04617,R11329 RC00064,RC00141,RC01012 ko00000,ko00001,ko00002,ko01000,ko01011 Bacteria 2GK0Y@201174,4DNW8@85009,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein gnl|extdb|FAM19036-p1-1.1_001783 1171373.PACID_12800 7.2e-297 1025.8 Propionibacteriales murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2158c Bacteria 2GIS2@201174,4DN64@85009,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan gnl|extdb|FAM19036-p1-1.1_001785 1171373.PACID_12780 1.1e-66 259.2 Actinobacteria ftsL ko:K05589,ko:K12065 ko00000,ko02044,ko03036 3.A.7.11.1 Bacteria 2GXRG@201174,COG2919@1,COG2919@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic gnl|extdb|FAM19036-p1-1.1_001786 1171373.PACID_12770 2.1e-177 628.2 Propionibacteriales rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 2GJGK@201174,4DPXU@85009,COG0275@1,COG0275@2 NA|NA|NA M Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA gnl|extdb|FAM19036-p1-1.1_001787 1171373.PACID_12760 3.2e-74 284.3 Propionibacteriales mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 2IHUB@201174,4DQJP@85009,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family gnl|extdb|FAM19036-p1-1.1_001789 1171373.PACID_12740 3.3e-228 797.3 Propionibacteriales Bacteria 2GIWE@201174,4DNDP@85009,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 gnl|extdb|FAM19036-p1-1.1_001790 1171373.PACID_12730 0.0 1340.9 Propionibacteriales Bacteria 2HQBB@201174,4DNMN@85009,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues gnl|extdb|FAM19036-p1-1.1_001791 754252.PFREUD_15610 2e-09 68.9 Bacteria Bacteria 2E49S@1,32Z5G@2 NA|NA|NA S Protein of unknown function (DUF3040) gnl|extdb|FAM19036-p1-1.1_001792 1171373.PACID_12710 1.4e-214 751.9 Propionibacteriales gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 iSFV_1184.SFV_2953 Bacteria 2GJ47@201174,4DNKG@85009,COG0404@1,COG0404@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine gnl|extdb|FAM19036-p1-1.1_001793 1171373.PACID_12700 1e-63 249.2 Propionibacteriales gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 2IKN2@201174,4DR5S@85009,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gnl|extdb|FAM19036-p1-1.1_001794 1171373.PACID_12690 0.0 1978.0 Propionibacteriales gcvP GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3318 Bacteria 2GJ11@201174,4DNP8@85009,COG0403@1,COG0403@2,COG1003@1,COG1003@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gnl|extdb|FAM19036-p1-1.1_001795 1171373.PACID_12680 7.2e-172 609.8 Propionibacteriales nodI ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 Bacteria 2GIY8@201174,4DPYJ@85009,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM19036-p1-1.1_001796 1171373.PACID_12670 1.3e-159 568.9 Propionibacteriales nodJ ko:K09694 ko02010,map02010 M00252 ko00000,ko00001,ko00002,ko02000 3.A.1.102 Bacteria 2GVC2@201174,4DQNH@85009,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter gnl|extdb|FAM19036-p1-1.1_001798 1171373.PACID_12650 1.5e-118 432.2 Propionibacteriales ko:K19776 ko00000,ko03000 Bacteria 2GKBM@201174,4DQBS@85009,COG2186@1,COG2186@2 NA|NA|NA K FCD gnl|extdb|FAM19036-p1-1.1_001799 1171373.PACID_12640 2.3e-98 364.8 Propionibacteriales gntK 1.1.1.343,1.1.1.44,2.7.1.12,3.1.1.31 ko:K00033,ko:K00851,ko:K01057 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R01528,R01737,R02035,R10221 RC00001,RC00002,RC00017,RC00537,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMW2@201174,4DQ7A@85009,COG3265@1,COG3265@2 NA|NA|NA G Shikimate kinase gnl|extdb|FAM19036-p1-1.1_001800 1171373.PACID_12630 5.6e-237 826.6 Propionibacteriales gnuT ko:K03299 ko00000,ko02000 2.A.8 Bacteria 2GITQ@201174,4DN1V@85009,COG2610@1,COG2610@2 NA|NA|NA EG GntP family permease gnl|extdb|FAM19036-p1-1.1_001801 1171373.PACID_12620 1.9e-166 591.7 Propionibacteriales gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2DH@201174,4DN6Y@85009,COG1023@1,COG1023@2 NA|NA|NA G 6-phosphogluconate dehydrogenase, decarboxylating gnl|extdb|FAM19036-p1-1.1_001802 1171373.PACID_12610 3e-72 277.7 Propionibacteriales ibpA ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2IHVJ@201174,4DQU3@85009,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) gnl|extdb|FAM19036-p1-1.1_001803 1171373.PACID_12600 3.3e-124 451.1 Bacteria Bacteria COG0596@1,COG0596@2 NA|NA|NA S hydrolase activity, acting on ester bonds gnl|extdb|FAM19036-p1-1.1_001804 1171373.PACID_12590 1.7e-148 531.9 Propionibacteriales ssuB2 ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00436 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 Bacteria 2IG4B@201174,4DWPA@85009,COG1116@1,COG1116@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_001806 1171373.PACID_12570 6.8e-196 689.9 Actinobacteria ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2IHFG@201174,COG0715@1,COG0715@2 NA|NA|NA P NMT1-like family gnl|extdb|FAM19036-p1-1.1_001808 1171373.PACID_12540 0.0 1434.9 Propionibacteriales Bacteria 2GK30@201174,4DPXT@85009,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase gnl|extdb|FAM19036-p1-1.1_001809 1171373.PACID_12530 4.6e-171 607.1 Propionibacteriales metF GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJTN@201174,4DPM1@85009,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase gnl|extdb|FAM19036-p1-1.1_001810 1171373.PACID_12520 1.7e-199 701.8 Propionibacteriales idsA 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2GJEK@201174,4DNU8@85009,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family gnl|extdb|FAM19036-p1-1.1_001811 1171373.PACID_12510 1.1e-121 442.6 Actinobacteria thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iJN678.thiE,iNJ661.Rv0414c Bacteria 2GKCN@201174,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) gnl|extdb|FAM19036-p1-1.1_001813 1171373.PACID_12490 1.9e-227 795.0 Propionibacteriales Bacteria 2GJ1J@201174,4DPC3@85009,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM19036-p1-1.1_001814 1171373.PACID_12480 2.5e-164 584.7 Propionibacteriales ydeD Bacteria 2I8X5@201174,4DPV8@85009,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM19036-p1-1.1_001815 1171373.PACID_12470 2.5e-126 458.0 Propionibacteriales Bacteria 2GNHK@201174,4DQBG@85009,COG2220@1,COG2220@2 NA|NA|NA S Beta-lactamase superfamily domain gnl|extdb|FAM19036-p1-1.1_001816 1171373.PACID_12460 3.9e-262 910.2 Propionibacteriales aroH 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJBX@201174,4DNES@85009,COG3200@1,COG3200@2 NA|NA|NA E Belongs to the class-II DAHP synthase family gnl|extdb|FAM19036-p1-1.1_001817 1171373.PACID_12450 2.2e-122 444.9 Propionibacteriales degU ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2GIVA@201174,4DPAM@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_001818 1171373.PACID_12440 3.6e-211 740.7 Propionibacteriales Bacteria 2GJ4J@201174,4DNBA@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase-like ATPases gnl|extdb|FAM19036-p1-1.1_001819 1171373.PACID_12430 7.3e-102 377.1 Bacteria 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria COG0204@1,COG0204@2 NA|NA|NA I Acyl-transferase gnl|extdb|FAM19036-p1-1.1_001820 1171373.PACID_12420 4.6e-148 530.4 Propionibacteriales plsC2 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJ6V@201174,4DP1S@85009,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase gnl|extdb|FAM19036-p1-1.1_001821 1171373.PACID_12410 5.3e-206 723.4 Propionibacteriales glk 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJCQ@201174,4DNXD@85009,COG1940@1,COG1940@2 NA|NA|NA GK ROK family gnl|extdb|FAM19036-p1-1.1_001822 1171373.PACID_12400 8.1e-125 453.8 Propionibacteriales ko:K21471,ko:K21473 ko00000,ko01000,ko01002,ko01011 Bacteria 2GIWB@201174,4DQU1@85009,COG0791@1,COG0791@2,COG3883@1,COG3883@2 NA|NA|NA M NlpC/P60 family gnl|extdb|FAM19036-p1-1.1_001823 1171373.PACID_12380 0.0 1173.3 Propionibacteriales cho GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 ko:K02342,ko:K03763,ko:K05984 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GMC0@201174,4DNVQ@85009,COG0322@1,COG0322@2,COG2176@1,COG2176@2 NA|NA|NA L DNA polymerase III, epsilon subunit gnl|extdb|FAM19036-p1-1.1_001824 1171373.PACID_12370 8.7e-41 172.6 Actinobacteria QU41_18010 2.4.2.18 ko:K00766,ko:K03719 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000,ko03000,ko03036 Bacteria 2IQD4@201174,COG1522@1,COG1522@2 NA|NA|NA K AsnC family gnl|extdb|FAM19036-p1-1.1_001826 1171373.PACID_12350 3e-95 354.4 Propionibacteriales ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 2IFUE@201174,4DQA4@85009,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gnl|extdb|FAM19036-p1-1.1_001827 1171373.PACID_12340 4.1e-70 271.9 Propionibacteriales rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GXD5@201174,4DVXM@85009,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel gnl|extdb|FAM19036-p1-1.1_001829 754252.PFREUD_15810 1.3e-24 120.2 Bacteria pppA 3.4.23.43 ko:K02654 M00331 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria COG1989@1,COG1989@2 NA|NA|NA NOU aspartic-type endopeptidase activity gnl|extdb|FAM19036-p1-1.1_001830 1171373.PACID_12310 1.2e-192 679.1 Propionibacteriales trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM4G@201174,4DP4R@85009,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) gnl|extdb|FAM19036-p1-1.1_001831 1171373.PACID_12300 7.2e-71 273.1 Propionibacteriales GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 2II71@201174,4DQR3@85009,COG0784@1,COG0784@2 NA|NA|NA T cheY-homologous receiver domain gnl|extdb|FAM19036-p1-1.1_001834 1171373.PACID_12270 7.1e-200 703.0 Propionibacteriales qcrA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03890,ko:K15878 ko00190,ko01100,map00190,map01100 M00151 ko00000,ko00001,ko00002 iAF987.Gmet_0538 Bacteria 2GIX6@201174,4DNGA@85009,COG0723@1,COG0723@2 NA|NA|NA C Rieske [2Fe-2S] domain gnl|extdb|FAM19036-p1-1.1_001835 1171373.PACID_12260 0.0 1172.9 Propionibacteriales petD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944 ko:K00412,ko:K02635,ko:K02637,ko:K03887,ko:K03891,ko:K15879 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 ko00000,ko00001,ko00002,ko00194,ko03029 Bacteria 2GJ1E@201174,4DNCY@85009,COG1290@1,COG1290@2 NA|NA|NA C Cytochrome b gnl|extdb|FAM19036-p1-1.1_001836 1171373.PACID_12250 3.1e-59 234.2 Propionibacteriales ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 ko:K00567,ko:K07443 ko00000,ko01000,ko03400 Bacteria 2I07B@201174,4DW31@85009,COG3695@1,COG3695@2 NA|NA|NA L 6-O-methylguanine DNA methyltransferase, DNA binding domain gnl|extdb|FAM19036-p1-1.1_001837 1171373.PACID_12240 4.2e-275 953.4 Propionibacteriales guaC GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016020,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iEC042_1314.EC042_0103,iECIAI39_1322.ECIAI39_0105,iECUMN_1333.ECUMN_0102 Bacteria 2GNDC@201174,4DN4P@85009,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F IMP dehydrogenase GMP reductase gnl|extdb|FAM19036-p1-1.1_001838 1171373.PACID_12230 1.7e-69 268.5 Propionibacteriales ctaF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2D9MJ@1,2ISCJ@201174,32TTI@2,4DWW4@85009 NA|NA|NA C Belongs to the cytochrome c oxidase bacterial subunit CtaF family gnl|extdb|FAM19036-p1-1.1_001841 1171373.PACID_12200 1.5e-61 241.9 Propionibacteriales erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 2IHR0@201174,4DR9B@85009,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family gnl|extdb|FAM19036-p1-1.1_001842 1171373.PACID_12190 7.6e-197 693.0 Bacteria glxK GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria COG1929@1,COG1929@2 NA|NA|NA G organic acid phosphorylation gnl|extdb|FAM19036-p1-1.1_001843 1171373.PACID_12180 1.6e-45 188.3 Propionibacteriales Bacteria 2E7WR@1,2I8C0@201174,332BD@2,4DS76@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001844 1171373.PACID_12170 6.9e-131 473.4 Propionibacteriales pspA ko:K03969 ko00000 Bacteria 2GP0K@201174,4DPJS@85009,COG1842@1,COG1842@2 NA|NA|NA KT PspA/IM30 family gnl|extdb|FAM19036-p1-1.1_001845 1171373.PACID_12160 4.4e-102 377.5 Propionibacteriales GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 Bacteria 2AN86@1,2HWWU@201174,31D67@2,4DRVQ@85009 NA|NA|NA S Protein of unknown function (DUF3043) gnl|extdb|FAM19036-p1-1.1_001846 267747.PPA0696 2.2e-10 71.2 Propionibacteriales Bacteria 2EFWK@1,2IQXQ@201174,339NW@2,4DSKV@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001851 1171373.PACID_12110 0.0 1271.9 Propionibacteriales GO:0008150,GO:0040007 ko:K02351,ko:K07245 ko00000,ko02000 9.B.62.1 Bacteria 2GKIR@201174,4DPN3@85009,COG3336@1,COG3336@2 NA|NA|NA P Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) gnl|extdb|FAM19036-p1-1.1_001852 1171373.PACID_12100 0.0 1359.7 Propionibacteriales 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2GIRF@201174,4DN8M@85009,COG2217@1,COG2217@2 NA|NA|NA P Heavy-metal-associated domain gnl|extdb|FAM19036-p1-1.1_001853 1171373.PACID_12090 8.8e-176 622.9 Propionibacteriales lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 2GKD4@201174,4DPBB@85009,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives gnl|extdb|FAM19036-p1-1.1_001854 1171373.PACID_12080 4.8e-121 440.7 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2AUFS@1,2GIXC@201174,31K3Y@2,4DQHR@85009 NA|NA|NA S Domain of unknown function (DUF4191) gnl|extdb|FAM19036-p1-1.1_001856 1171373.PACID_12060 1.2e-74 285.8 Propionibacteriales Bacteria 2IHPB@201174,4DWIB@85009,COG0517@1,COG0517@2 NA|NA|NA S Domain in cystathionine beta-synthase and other proteins. gnl|extdb|FAM19036-p1-1.1_001857 1171373.PACID_12050 1.8e-108 398.7 Propionibacteriales Bacteria 2HKKQ@201174,4DSGH@85009,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein gnl|extdb|FAM19036-p1-1.1_001858 1171373.PACID_12040 6.3e-210 736.5 Bacteria 2.4.1.11 ko:K16150 ko00500,ko01100,map00500,map01100 R00292 RC00005 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups gnl|extdb|FAM19036-p1-1.1_001859 1171373.PACID_12030 6.8e-72 276.6 Propionibacteriales Bacteria 2HZE5@201174,4DSBQ@85009,COG1714@1,COG1714@2 NA|NA|NA S RDD family gnl|extdb|FAM19036-p1-1.1_001860 1171373.PACID_12020 2.4e-210 738.0 Propionibacteriales Bacteria 28K27@1,2I942@201174,2Z9RK@2,4DWE9@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001861 1171373.PACID_12010 8.2e-284 982.2 Propionibacteriales glnA GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GMN1@201174,4DNAS@85009,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase gnl|extdb|FAM19036-p1-1.1_001862 1370125.AUWT01000066_gene3706 9.2e-30 136.0 Mycobacteriaceae ko:K07334 ko00000,ko02048 Bacteria 23BGB@1762,2IT6K@201174,COG3549@1,COG3549@2 NA|NA|NA S RelE-like toxin of type II toxin-antitoxin system HigB gnl|extdb|FAM19036-p1-1.1_001863 1171373.PACID_11990 2.4e-47 194.5 Actinobacteria higA ko:K21498 ko00000,ko02048 Bacteria 2IR2S@201174,COG3093@1,COG3093@2 NA|NA|NA K Addiction module antidote protein, HigA gnl|extdb|FAM19036-p1-1.1_001864 1171373.PACID_11980 3e-171 607.8 Actinobacteria Bacteria 2GMGZ@201174,COG1434@1,COG1434@2 NA|NA|NA V DUF218 domain gnl|extdb|FAM19036-p1-1.1_001865 1171373.PACID_11970 8.4e-148 529.6 Propionibacteriales yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKHZ@201174,4DN28@85009,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family gnl|extdb|FAM19036-p1-1.1_001866 1171373.PACID_11960 5.6e-215 753.4 Bacteria yjjP Bacteria COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA H response to peptide gnl|extdb|FAM19036-p1-1.1_001867 1171373.PACID_11950 0.0 1786.2 Propionibacteriales glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 ko00000,ko01000 Bacteria 2GJ91@201174,4DPAV@85009,COG1391@1,COG1391@2 NA|NA|NA H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell gnl|extdb|FAM19036-p1-1.1_001868 1171373.PACID_11940 1.1e-124 452.6 Bacteria Bacteria COG3255@1,COG3255@2 NA|NA|NA I Sterol carrier protein gnl|extdb|FAM19036-p1-1.1_001870 1171373.PACID_11920 2.5e-134 485.0 Propionibacteriales Bacteria 2DYIV@1,2I04P@201174,34A0Z@2,4DVNC@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001871 1171373.PACID_11910 2.2e-167 594.7 Propionibacteriales map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2GKIZ@201174,4DN75@85009,COG0024@1,COG0024@2 NA|NA|NA J Methionine aminopeptidase gnl|extdb|FAM19036-p1-1.1_001872 1171373.PACID_11900 1.8e-206 724.9 Propionibacteriales corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 2GKNZ@201174,4DPRY@85009,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein gnl|extdb|FAM19036-p1-1.1_001873 1051006.HMPREF1162_1050 7.6e-26 125.2 Propionibacteriales ko:K19720 ko04611,ko04926,ko04933,ko04974,ko05146,map04611,map04926,map04933,map04974,map05146 ko00000,ko00001,ko00536 Bacteria 2AUYC@1,2IJE4@201174,31KMU@2,4DVBZ@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001875 1171373.PACID_11880 1.4e-126 459.1 Actinobacteria ko:K07164 ko00000 Bacteria 2GP84@201174,COG1579@1,COG1579@2 NA|NA|NA S Zn-ribbon protein, possibly nucleic acid-binding gnl|extdb|FAM19036-p1-1.1_001876 1171373.PACID_11870 1.2e-244 852.0 Actinobacteria Bacteria 2GNUF@201174,COG0531@1,COG0531@2 NA|NA|NA E amino acid gnl|extdb|FAM19036-p1-1.1_001877 1171373.PACID_11860 1.5e-171 608.6 Actinobacteria Bacteria 2GP6F@201174,COG0388@1,COG0388@2 NA|NA|NA S Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates gnl|extdb|FAM19036-p1-1.1_001878 1171373.PACID_11850 3.6e-249 867.1 Propionibacteriales gabT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GIS9@201174,4DPFZ@85009,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gnl|extdb|FAM19036-p1-1.1_001879 1171373.PACID_11840 4.9e-135 487.3 Propionibacteriales hemD 2.1.1.107,4.2.1.75 ko:K01719,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKMM@201174,4DP10@85009,COG1587@1,COG1587@2 NA|NA|NA HK Uroporphyrinogen-III synthase HemD gnl|extdb|FAM19036-p1-1.1_001881 1171373.PACID_11810 3.9e-159 567.4 Bacteria ctaB 2.5.1.141 ko:K02257,ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07411,R07412 RC00769,RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 3.D.4.4 Bacteria COG1612@1,COG1612@2 NA|NA|NA O heme a metabolic process gnl|extdb|FAM19036-p1-1.1_001882 1171373.PACID_11800 6.3e-114 416.8 Bacteria Bacteria COG2227@1,COG2227@2 NA|NA|NA H 3-demethylubiquinone-9 3-O-methyltransferase activity gnl|extdb|FAM19036-p1-1.1_001883 1171373.PACID_11790 1.3e-71 275.8 Propionibacteriales Bacteria 2CAW2@1,2IB15@201174,32RS7@2,4DQMM@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001884 1171373.PACID_11780 2.2e-177 628.6 Propionibacteriales mgtE Bacteria 2GMMK@201174,4DPA3@85009,COG2239@1,COG2239@2 NA|NA|NA P MgtE intracellular N domain gnl|extdb|FAM19036-p1-1.1_001885 1171373.PACID_11770 4.6e-81 307.4 Propionibacteriales Bacteria 2GJRV@201174,4DQT8@85009,COG4420@1,COG4420@2 NA|NA|NA S Protein of unknown function (DUF1003) gnl|extdb|FAM19036-p1-1.1_001886 1171373.PACID_11760 1.9e-209 734.9 Propionibacteriales mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040007,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K02612,ko:K03593,ko:K04488 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001,ko03029,ko03036 Bacteria 2GJUZ@201174,4DNNW@85009,COG0489@1,COG0489@2,COG2151@1,COG2151@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP gnl|extdb|FAM19036-p1-1.1_001887 1171373.PACID_11750 6.8e-48 196.8 Propionibacteriales tatB GO:0008150,GO:0040007 ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2IR0U@201174,4DRKC@85009,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation gnl|extdb|FAM19036-p1-1.1_001888 1171373.PACID_11740 3.4e-155 554.3 Propionibacteriales dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ34@201174,4DNA0@85009,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) gnl|extdb|FAM19036-p1-1.1_001889 1171373.PACID_11730 3.5e-112 411.0 Propionibacteriales safC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 2GPEV@201174,4DNEI@85009,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase gnl|extdb|FAM19036-p1-1.1_001892 1171373.PACID_11710 6.3e-99 366.7 Propionibacteriales Bacteria 2GNZF@201174,4DR2P@85009,COG5516@1,COG5516@2 NA|NA|NA S Putative stress-induced transcription regulator gnl|extdb|FAM19036-p1-1.1_001893 1171373.PACID_11700 5.7e-241 839.7 Propionibacteriales glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2768 Bacteria 2I2EF@201174,4DPN8@85009,COG0448@1,COG0448@2 NA|NA|NA G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans gnl|extdb|FAM19036-p1-1.1_001894 1171373.PACID_11690 9.1e-228 795.8 Propionibacteriales glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 2I2EE@201174,4DN2C@85009,COG0297@1,COG0297@2 NA|NA|NA G Glycosyl transferases group 1 gnl|extdb|FAM19036-p1-1.1_001895 1171373.PACID_11680 8.4e-23 112.1 Actinobacteria Bacteria 2E39N@1,2GQFF@201174,32Y97@2 NA|NA|NA S Protein of unknown function (DUF3117) gnl|extdb|FAM19036-p1-1.1_001896 1171373.PACID_11670 3.5e-46 190.7 Propionibacteriales Bacteria 2DR5U@1,2GX63@201174,33AAR@2,4DWZI@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001897 1171373.PACID_11660 2e-143 515.0 Propionibacteriales fmt2 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2GKJH@201174,4DPM7@85009,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family gnl|extdb|FAM19036-p1-1.1_001898 1171373.PACID_11650 5.4e-211 740.0 Propionibacteriales dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK09@201174,4DN9X@85009,COG0624@1,COG0624@2 NA|NA|NA E Succinyl-diaminopimelate desuccinylase gnl|extdb|FAM19036-p1-1.1_001899 1171373.PACID_11640 2e-177 628.2 Propionibacteriales dapD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1201c Bacteria 2GIZ9@201174,4DMZE@85009,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA gnl|extdb|FAM19036-p1-1.1_001901 1171373.PACID_11620 1.5e-142 512.3 Actinobacteria Bacteria 2GJTM@201174,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM19036-p1-1.1_001902 1171373.PACID_11610 8e-210 736.1 Propionibacteriales dapC Bacteria 2GJMI@201174,4DNQA@85009,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II gnl|extdb|FAM19036-p1-1.1_001903 1171373.PACID_11600 2.4e-58 231.1 Actinobacteria fdxA ko:K05524 ko00000 Bacteria 2IKVN@201174,COG1146@1,COG1146@2 NA|NA|NA C Ferredoxin gnl|extdb|FAM19036-p1-1.1_001904 1171373.PACID_11590 0.0 1127.9 Propionibacteriales vanW Bacteria 2GISH@201174,4DN8K@85009,COG2720@1,COG2720@2 NA|NA|NA V Putative peptidoglycan binding domain gnl|extdb|FAM19036-p1-1.1_001905 1171373.PACID_11580 1.1e-239 835.5 Propionibacteriales yfeW GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008658,GO:0009002,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1901681 3.4.16.4 ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2GJQG@201174,4DPYC@85009,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM19036-p1-1.1_001906 1171373.PACID_11570 1.7e-265 921.4 Propionibacteriales pntB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 iSBO_1134.SBO_1534,iYL1228.KPN_01527 Bacteria 2GNKB@201174,4DT4M@85009,COG1282@1,COG1282@2 NA|NA|NA C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane gnl|extdb|FAM19036-p1-1.1_001907 1171373.PACID_11560 3.6e-269 933.7 Propionibacteriales pntA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 iEcE24377_1341.EcE24377A_1810 Bacteria 2I2FZ@201174,4DNG1@85009,COG3288@1,COG3288@2 NA|NA|NA C NAD(P) transhydrogenase, alpha subunit gnl|extdb|FAM19036-p1-1.1_001908 1171373.PACID_11550 1.5e-239 835.1 Propionibacteriales pimH Bacteria 2I2EY@201174,4DNW0@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_001909 1171373.PACID_11540 4e-78 297.4 Propionibacteriales Bacteria 2IFQ9@201174,4DS13@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM19036-p1-1.1_001911 1171373.PACID_11500 2.4e-204 718.0 Bacteria GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria COG1403@1,COG1403@2 NA|NA|NA V endonuclease activity gnl|extdb|FAM19036-p1-1.1_001912 1171373.PACID_11490 0.0 1370.5 Propionibacteriales tkt GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ1K@201174,4DN1Y@85009,COG0021@1,COG0021@2 NA|NA|NA G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate gnl|extdb|FAM19036-p1-1.1_001913 1171373.PACID_11480 0.0 1161.7 Propionibacteriales araB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008741,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046373,GO:0046835,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 iBWG_1329.BWG_0059,iECH74115_1262.ECH74115_0068,iECSP_1301.ECSP_0067,iECs_1301.ECs0067,iG2583_1286.G2583_0066,iPC815.YPO2254,iZ_1308.Z0072 Bacteria 2H531@201174,4DP9J@85009,COG1069@1,COG1069@2 NA|NA|NA G FGGY family of carbohydrate kinases, C-terminal domain gnl|extdb|FAM19036-p1-1.1_001914 1171373.PACID_11470 1.4e-261 908.3 Propionibacteriales egsA 1.1.1.261 ko:K00096 ko00564,map00564 R05679,R05680 RC00029 ko00000,ko00001,ko01000 Bacteria 2GKWA@201174,4DQ5E@85009,COG0371@1,COG0371@2 NA|NA|NA C Iron-containing alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_001915 1171373.PACID_11460 1.3e-309 1068.1 Propionibacteriales Bacteria 2I41D@201174,4DQK0@85009,COG1069@1,COG1069@2 NA|NA|NA G FGGY family of carbohydrate kinases, N-terminal domain gnl|extdb|FAM19036-p1-1.1_001916 1171373.PACID_11450 7.4e-163 579.7 Propionibacteriales araL 3.1.3.41 ko:K01101,ko:K02101,ko:K02566 ko00627,ko01120,map00627,map01120 R03024 RC00151 ko00000,ko00001,ko01000 Bacteria 2IBHB@201174,4DQQ5@85009,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase gnl|extdb|FAM19036-p1-1.1_001917 1171373.PACID_11440 2.8e-175 621.3 Actinobacteria Bacteria 2IBQ6@201174,2ZYP7@2,arCOG04584@1 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001918 1171373.PACID_11430 2.7e-85 321.2 Actinobacteria rpiB GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIDQ@201174,COG0698@1,COG0698@2 NA|NA|NA G Ribose 5-phosphate isomerase gnl|extdb|FAM19036-p1-1.1_001919 1171373.PACID_11420 4.5e-133 480.7 Propionibacteriales Bacteria 2IBBZ@201174,4DQU0@85009,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain gnl|extdb|FAM19036-p1-1.1_001920 1171373.PACID_11410 1.9e-89 335.1 Propionibacteriales gpt 2.4.2.22 ko:K00769,ko:K07101 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 2GN86@201174,4DRPW@85009,COG2236@1,COG2236@2 NA|NA|NA F Phosphoribosyl transferase domain gnl|extdb|FAM19036-p1-1.1_001921 1171373.PACID_11400 1.8e-309 1067.8 Propionibacteriales dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0030246,GO:0042221,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 2.7.1.121,2.7.1.209,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K20901 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059,R11460 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJV9@201174,4DN06@85009,COG2376@1,COG2376@2 NA|NA|NA G Dihydroxyacetone kinase gnl|extdb|FAM19036-p1-1.1_001922 1171373.PACID_11390 3e-198 697.6 Propionibacteriales tdh Bacteria 2GKC7@201174,4DRH1@85009,COG1063@1,COG1063@2 NA|NA|NA E Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM19036-p1-1.1_001923 1171373.PACID_11380 0.0 2266.9 Propionibacteriales putA 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 Bacteria 2GM5R@201174,4DQ4S@85009,COG0506@1,COG0506@2,COG1012@1,COG1012@2 NA|NA|NA C Proline dehydrogenase gnl|extdb|FAM19036-p1-1.1_001924 1171373.PACID_11370 7.4e-264 916.0 Propionibacteriales ko:K03457 ko00000 2.A.39 Bacteria 2GJ6B@201174,4DNUH@85009,COG1457@1,COG1457@2 NA|NA|NA F Belongs to the purine-cytosine permease (2.A.39) family gnl|extdb|FAM19036-p1-1.1_001925 1171373.PACID_11360 3.3e-103 380.9 Propionibacteriales Bacteria 2IN6N@201174,4DRFV@85009,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family gnl|extdb|FAM19036-p1-1.1_001926 1171373.PACID_11350 9.4e-148 529.6 Propionibacteriales psaA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 2GM1K@201174,4DVAK@85009,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic gnl|extdb|FAM19036-p1-1.1_001927 1171373.PACID_11340 3.7e-151 540.8 Propionibacteriales fhuC ko:K02074,ko:K06994,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2GP3A@201174,4DTXB@85009,COG1121@1,COG1121@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_001929 1171373.PACID_11320 2.6e-45 188.0 Actinobacteria ywzG Bacteria 2IQSE@201174,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR family protein gnl|extdb|FAM19036-p1-1.1_001930 1171373.PACID_11310 2.1e-199 701.8 Actinobacteria Bacteria 2CA5R@1,2GM6V@201174,2Z81H@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001931 1171373.PACID_11300 8.1e-139 500.0 Propionibacteriales pknD ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJQW@201174,4DQ7J@85009,COG0834@1,COG0834@2 NA|NA|NA ET amino acid gnl|extdb|FAM19036-p1-1.1_001932 1171373.PACID_11290 1.3e-139 502.7 Propionibacteriales pknD ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJQW@201174,4DQ7J@85009,COG0834@1,COG0834@2 NA|NA|NA ET amino acid gnl|extdb|FAM19036-p1-1.1_001933 1171373.PACID_11280 2.5e-135 488.4 Propionibacteriales pknD ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJQW@201174,4DQ7J@85009,COG0834@1,COG0834@2 NA|NA|NA ET amino acid gnl|extdb|FAM19036-p1-1.1_001934 1171373.PACID_11270 1.3e-157 562.4 Propionibacteriales yecS ko:K02029,ko:K10009 ko02010,map02010 M00234,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14 Bacteria 2GJJ9@201174,4DQAE@85009,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001940 1171373.PACID_11210 0.0 1437.6 Propionibacteriales mutB 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM65@201174,4DWYX@85009,COG1884@1,COG1884@2,COG2185@1,COG2185@2 NA|NA|NA I Methylmalonyl-CoA mutase gnl|extdb|FAM19036-p1-1.1_001941 1171373.PACID_11200 0.0 1239.2 Propionibacteriales mutA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944 2.7.7.7,5.4.99.2,5.4.99.63 ko:K01847,ko:K03763,ko:K14447 ko00230,ko00240,ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko03030,ko03430,ko03440,map00230,map00240,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map03030,map03430,map03440 M00260,M00373,M00376,M00741 R00375,R00376,R00377,R00378,R00833,R09292 RC00395,RC02795,RC02835 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GNBQ@201174,4DNT9@85009,COG1884@1,COG1884@2 NA|NA|NA I Methylmalonyl-CoA mutase gnl|extdb|FAM19036-p1-1.1_001942 1171373.PACID_11180 2.5e-180 637.9 Propionibacteriales pldB 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Bacteria 2GPA8@201174,4DRD1@85009,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 gnl|extdb|FAM19036-p1-1.1_001944 1171373.PACID_11160 1.7e-253 881.3 Propionibacteriales nplT 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 2GJUT@201174,4DT3W@85009,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain gnl|extdb|FAM19036-p1-1.1_001946 1171373.PACID_11140 1.2e-83 315.8 Propionibacteriales tpx GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 2II20@201174,4DQU5@85009,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides gnl|extdb|FAM19036-p1-1.1_001947 1171373.PACID_11130 4.3e-175 620.5 Propionibacteriales mocA 1.1.1.91 ko:K05882 ko00000,ko01000 Bacteria 2GMNA@201174,4DUK1@85009,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM19036-p1-1.1_001948 1171373.PACID_11120 9.2e-183 646.4 Propionibacteriales Bacteria 2GISM@201174,4DPIE@85009,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase gnl|extdb|FAM19036-p1-1.1_001949 1171373.PACID_11110 1.3e-85 322.4 Propionibacteriales Bacteria 2IGKE@201174,4DWV6@85009,COG2716@1,COG2716@2 NA|NA|NA E ACT domain gnl|extdb|FAM19036-p1-1.1_001952 1171373.PACID_11080 4.8e-75 287.0 Actinobacteria Bacteria 2CEMW@1,2ISZX@201174,348ZF@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001953 1171373.PACID_11070 1.2e-140 505.8 Bacteria Bacteria COG5607@1,COG5607@2 NA|NA|NA F PFAM CHAD domain containing protein gnl|extdb|FAM19036-p1-1.1_001954 1171373.PACID_11060 1.8e-273 948.0 Propionibacteriales proP ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,4DPQY@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM19036-p1-1.1_001955 1171373.PACID_11050 1.4e-270 938.3 Propionibacteriales proP ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,4DPQY@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM19036-p1-1.1_001956 1171373.PACID_11040 4.8e-158 563.9 Actinobacteria 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 2GN47@201174,COG0604@1,COG0604@2 NA|NA|NA C NAD(P)H quinone oxidoreductase, PIG3 family gnl|extdb|FAM19036-p1-1.1_001957 1171373.PACID_11030 1.2e-118 432.6 Actinobacteria Bacteria 2GJRY@201174,COG2197@1,COG2197@2 NA|NA|NA T response regulator gnl|extdb|FAM19036-p1-1.1_001959 1171373.PACID_11010 2.3e-127 461.8 Bacteria Bacteria COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_001960 1171373.PACID_11000 6.1e-263 912.9 Bacteria Bacteria COG1511@1,COG1511@2 NA|NA|NA Q domain protein gnl|extdb|FAM19036-p1-1.1_001961 1122997.AUDD01000006_gene31 3.6e-81 307.8 Propionibacteriales pncA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 ko:K08281,ko:K12132 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000,ko01001 iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802 Bacteria 2IFQW@201174,4DQD6@85009,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family gnl|extdb|FAM19036-p1-1.1_001962 1171373.PACID_10990 1.8e-104 385.2 Propionibacteriales ogt 2.1.1.63 ko:K00567 ko00000,ko01000,ko03400 Bacteria 2GKA9@201174,4DQTU@85009,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated gnl|extdb|FAM19036-p1-1.1_001963 1171373.PACID_10980 8.4e-87 326.2 Propionibacteriales Bacteria 2II47@201174,4DRDP@85009,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 gnl|extdb|FAM19036-p1-1.1_001964 1171373.PACID_10970 5.8e-82 310.5 Propionibacteriales Bacteria 2GR7H@201174,4DRC6@85009,COG2105@1,COG2105@2 NA|NA|NA S PFAM AIG2 family protein gnl|extdb|FAM19036-p1-1.1_001965 1451261.AS96_08305 2.2e-13 82.4 Actinobacteria Bacteria 2C06K@1,2IQHH@201174,32TKK@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001966 1121952.ATXT01000003_gene2507 1.1e-97 362.8 Microbacteriaceae Bacteria 2GNRS@201174,4FP95@85023,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family gnl|extdb|FAM19036-p1-1.1_001968 1171373.PACID_10930 1.3e-115 422.5 Propionibacteriales ymdC 2.7.1.95 ko:K00897,ko:K19299 br01600,ko00000,ko01000,ko01504 Bacteria 2HIED@201174,4DSIB@85009,COG3231@1,COG3231@2 NA|NA|NA J Phosphotransferase enzyme family gnl|extdb|FAM19036-p1-1.1_001969 1171373.PACID_10920 3.8e-93 347.4 Bacteria Bacteria COG1514@1,COG1514@2 NA|NA|NA J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester gnl|extdb|FAM19036-p1-1.1_001970 1171373.PACID_10910 2.4e-162 578.2 Bacteria Bacteria COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase gnl|extdb|FAM19036-p1-1.1_001971 1171373.PACID_10900 1e-92 346.3 Propionibacteriales Bacteria 2GN4K@201174,4DQBQ@85009,COG4832@1,COG4832@2 NA|NA|NA S GyrI-like small molecule binding domain gnl|extdb|FAM19036-p1-1.1_001972 1171373.PACID_10890 3.4e-103 380.9 Propionibacteriales Bacteria 2GKX0@201174,4DQP6@85009,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain gnl|extdb|FAM19036-p1-1.1_001973 1171373.PACID_10880 2e-100 371.7 Actinobacteria Bacteria 2IHF8@201174,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain gnl|extdb|FAM19036-p1-1.1_001974 1171373.PACID_10860 1.9e-44 185.3 Actinobacteria ko:K07064 ko00000 Bacteria 2IMQU@201174,COG1848@1,COG1848@2 NA|NA|NA S PIN domain gnl|extdb|FAM19036-p1-1.1_001975 593907.Celgi_0698 1.5e-62 245.7 Actinobacteria Bacteria 2IFNE@201174,COG0457@1,COG0457@2 NA|NA|NA S Tetratrico peptide repeat gnl|extdb|FAM19036-p1-1.1_001976 1171373.PACID_10840 8.3e-148 529.6 Propionibacteriales Bacteria 2I2DJ@201174,4DQ42@85009,COG3153@1,COG3153@2 NA|NA|NA S acetyltransferase gnl|extdb|FAM19036-p1-1.1_001977 1171373.PACID_10830 1e-72 279.3 Propionibacteriales GnaT 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria 2IR11@201174,4DVEQ@85009,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_001978 1171373.PACID_10820 1.8e-56 224.9 Actinobacteria Bacteria 2IRY1@201174,COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 gnl|extdb|FAM19036-p1-1.1_001979 1171373.PACID_10810 9.1e-53 212.6 Actinobacteria ko:K07075 ko00000 Bacteria 2IP8Y@201174,COG1669@1,COG1669@2 NA|NA|NA K Nucleotidyltransferase domain gnl|extdb|FAM19036-p1-1.1_001980 1171373.PACID_10800 2.3e-37 161.0 Actinobacteria Bacteria 2AP12@1,2GZ7H@201174,31E2A@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001982 1171373.PACID_22590 3.9e-237 827.0 Propionibacteriales Bacteria 2GM8F@201174,4DV2N@85009,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain gnl|extdb|FAM19036-p1-1.1_001983 1464048.JNZS01000003_gene1170 1.1e-88 334.3 Actinobacteria Bacteria 2BWH2@1,2H1NM@201174,32SU4@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001984 43354.JOIJ01000009_gene2914 1.1e-93 349.7 Pseudonocardiales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,4E04Y@85010,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter gnl|extdb|FAM19036-p1-1.1_001985 1171373.PACID_23800 3.8e-70 271.2 Propionibacteriales Bacteria 2GW5J@201174,4DRV2@85009,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain gnl|extdb|FAM19036-p1-1.1_001986 1416752.AYME01000002_gene919 1.7e-70 272.3 Microbacteriaceae Bacteria 2IFQM@201174,4FR6C@85023,COG3226@1,COG3226@2 NA|NA|NA K tetR family gnl|extdb|FAM19036-p1-1.1_001987 1171373.PACID_10540 1.9e-195 688.3 Propionibacteriales ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 2GIXI@201174,4DP3C@85009,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner gnl|extdb|FAM19036-p1-1.1_001988 1171373.PACID_10530 7.1e-180 636.3 Propionibacteriales ubiG Bacteria 2IIAX@201174,4DSFE@85009,COG3865@1,COG3865@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase gnl|extdb|FAM19036-p1-1.1_001989 1171373.PACID_10520 0.0 1390.2 Actinobacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IB3W@201174,COG0577@1,COG0577@2 NA|NA|NA V Efflux ABC transporter, permease protein gnl|extdb|FAM19036-p1-1.1_001991 1171373.PACID_10500 8.3e-243 845.9 Propionibacteriales apeB GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 ko:K01267 ko00000,ko01000,ko01002,ko04131 Bacteria 2GKW4@201174,4DPTA@85009,COG1362@1,COG1362@2 NA|NA|NA E Aminopeptidase I zinc metalloprotease (M18) gnl|extdb|FAM19036-p1-1.1_001992 1171373.PACID_10490 3e-205 721.1 Propionibacteriales rmuC ko:K09760 ko00000 Bacteria 2GP4U@201174,4DN8P@85009,COG1322@1,COG1322@2 NA|NA|NA S RmuC family gnl|extdb|FAM19036-p1-1.1_001993 1122997.AUDD01000030_gene217 3.9e-144 517.7 Propionibacteriales ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 2GIZ7@201174,4DP0N@85009,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis gnl|extdb|FAM19036-p1-1.1_001994 1171373.PACID_10480 1.8e-221 775.0 Propionibacteriales xseA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJAS@201174,4DNJ0@85009,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides gnl|extdb|FAM19036-p1-1.1_001995 1171373.PACID_10470 2.2e-38 164.5 Propionibacteriales xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GR0U@201174,4DS6T@85009,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides gnl|extdb|FAM19036-p1-1.1_001997 1171373.PACID_10450 4.1e-256 890.2 Propionibacteriales phoH ko:K07175 ko00000 Bacteria 2GK8U@201174,4DNRD@85009,COG1875@1,COG1875@2 NA|NA|NA T phosphate starvation-inducible protein PhoH gnl|extdb|FAM19036-p1-1.1_001998 1171373.PACID_10440 2.6e-126 458.0 Propionibacteriales yplQ ko:K11068 ko00000,ko02042 Bacteria 2GJGQ@201174,4DQ8R@85009,COG1272@1,COG1272@2 NA|NA|NA S Haemolysin-III related gnl|extdb|FAM19036-p1-1.1_001999 1171373.PACID_10430 5.8e-157 560.1 Propionibacteriales uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0033850,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 ko:K00806,ko:K12503 ko00900,ko01110,map00900,map01110 R06447,R08528 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2GJCP@201174,4DPJB@85009,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids gnl|extdb|FAM19036-p1-1.1_002000 1171373.PACID_10420 0.0 1389.8 Propionibacteriales yyaL ko:K06888 ko00000 Bacteria 2IE03@201174,4DWN1@85009,COG1331@1,COG1331@2 NA|NA|NA O Protein of unknown function, DUF255 gnl|extdb|FAM19036-p1-1.1_002002 1171373.PACID_10400 8.4e-78 296.2 Propionibacteriales Bacteria 2DRBP@1,2GX78@201174,33B4I@2,4DSVD@85009 NA|NA|NA S Domain of unknown function (DUF4307) gnl|extdb|FAM19036-p1-1.1_002003 1171373.PACID_10390 1.9e-86 325.1 Propionibacteriales greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 2GNZV@201174,4DQI3@85009,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides gnl|extdb|FAM19036-p1-1.1_002004 1122998.AUHZ01000026_gene36 3.2e-96 358.6 Propionibacteriales Bacteria 2B5R0@1,2IPMA@201174,31YKI@2,4DR93@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002005 1171373.PACID_10370 2.4e-164 585.1 Propionibacteriales GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K20469 ko00000,ko02000 2.A.86.1.7 Bacteria 2GK0H@201174,4DNK8@85009,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter gnl|extdb|FAM19036-p1-1.1_002006 1171373.PACID_10360 1.6e-128 465.3 Propionibacteriales ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ9Z@201174,4DN2B@85009,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gnl|extdb|FAM19036-p1-1.1_002007 1171373.PACID_10350 1.9e-123 448.4 Propionibacteriales msrA 1.8.4.11 ko:K07304 ko00000,ko01000 Bacteria 2GJ1S@201174,4DQ8G@85009,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine gnl|extdb|FAM19036-p1-1.1_002014 1171373.PACID_10270 3.2e-239 833.9 Propionibacteriales tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJPR@201174,4DNWH@85009,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) gnl|extdb|FAM19036-p1-1.1_002015 1171373.PACID_10260 1.6e-91 342.0 Propionibacteriales argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 2GKA5@201174,4DQUP@85009,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes gnl|extdb|FAM19036-p1-1.1_002016 1171373.PACID_10250 3.7e-108 397.5 Propionibacteriales tetR Bacteria 2HAGC@201174,4DS43@85009,COG1309@1,COG1309@2 NA|NA|NA K Tetracyclin repressor, C-terminal all-alpha domain gnl|extdb|FAM19036-p1-1.1_002017 1171373.PACID_10240 1.2e-205 722.2 Propionibacteriales bioB 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 iYO844.BSU30200 Bacteria 2GIUE@201174,4DQ0R@85009,COG0502@1,COG0502@2 NA|NA|NA H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism gnl|extdb|FAM19036-p1-1.1_002018 1171373.PACID_10230 0.0 1656.7 Propionibacteriales pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GMFD@201174,4DPEJ@85009,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily gnl|extdb|FAM19036-p1-1.1_002019 1171373.PACID_10220 3.1e-214 750.7 Propionibacteriales pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJGG@201174,4DPA8@85009,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily gnl|extdb|FAM19036-p1-1.1_002020 1171373.PACID_10210 1.3e-268 932.2 Actinobacteria Bacteria 2GJII@201174,COG5373@1,COG5373@2 NA|NA|NA D Predicted membrane protein (DUF2339) gnl|extdb|FAM19036-p1-1.1_002021 1171373.PACID_10200 2.9e-148 531.2 Actinobacteria tsnR 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJI6@201174,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gnl|extdb|FAM19036-p1-1.1_002022 1171373.PACID_10190 2e-56 224.9 Propionibacteriales rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHTN@201174,4DQY2@85009,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit gnl|extdb|FAM19036-p1-1.1_002023 1171373.PACID_10180 9.7e-29 132.1 Propionibacteriales rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQZW@201174,4DSHV@85009,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family gnl|extdb|FAM19036-p1-1.1_002024 765123.HMPREF9621_01330 2e-93 349.0 Propionibacteriales infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2GJGT@201174,4DNG8@85009,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins gnl|extdb|FAM19036-p1-1.1_002029 1171373.PACID_10130 1.2e-164 585.9 Bacteria Bacteria 299UX@1,2ZWWZ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002030 1171373.PACID_10120 9.7e-129 466.1 Propionibacteriales 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2GPP2@201174,4DQE2@85009,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain gnl|extdb|FAM19036-p1-1.1_002035 1171373.PACID_10070 2.4e-102 378.3 Propionibacteriales pepA ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ3@201174,4DQN3@85009,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like peptidase domain gnl|extdb|FAM19036-p1-1.1_002036 1171373.PACID_10070 3.2e-59 234.6 Propionibacteriales pepA ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ3@201174,4DQN3@85009,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like peptidase domain gnl|extdb|FAM19036-p1-1.1_002037 1171373.PACID_10060 2.6e-186 657.9 Actinobacteria yfeX ko:K07223 ko00000 Bacteria 2GMNJ@201174,COG2837@1,COG2837@2 NA|NA|NA P peroxidase gnl|extdb|FAM19036-p1-1.1_002038 1171373.PACID_10050 2e-146 525.0 Actinobacteria lin Bacteria 2GJMK@201174,COG1659@1,COG1659@2 NA|NA|NA S Bacteriocin gnl|extdb|FAM19036-p1-1.1_002040 1171373.PACID_10030 3.4e-161 574.3 Propionibacteriales ppx GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2GJBN@201174,4DQ85@85009,COG0248@1,COG0248@2 NA|NA|NA FP Ppx/GppA phosphatase family gnl|extdb|FAM19036-p1-1.1_002041 1171373.PACID_10020 2.1e-94 351.7 Propionibacteriales ppx2 3.6.1.11,3.6.1.40 ko:K01524,ko:K09009 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2I8CS@201174,4DQUA@85009,COG1507@1,COG1507@2 NA|NA|NA S Protein of unknown function (DUF501) gnl|extdb|FAM19036-p1-1.1_002042 1171373.PACID_10010 1.6e-88 332.0 Bacteria divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria COG2919@1,COG2919@2 NA|NA|NA D cell cycle gnl|extdb|FAM19036-p1-1.1_002043 1171373.PACID_10000 1.2e-236 825.5 Propionibacteriales eno 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2GJAY@201174,4DPWS@85009,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis gnl|extdb|FAM19036-p1-1.1_002045 1171373.PACID_09980 3.3e-87 327.8 Actinobacteria ppiD 5.2.1.8 ko:K03770,ko:K07533 ko00000,ko01000,ko03110 Bacteria 2ICFD@201174,COG0760@1,COG0760@2 NA|NA|NA O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation gnl|extdb|FAM19036-p1-1.1_002046 1171373.PACID_09970 0.0 2325.4 Propionibacteriales mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ42@201174,4DNWF@85009,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site gnl|extdb|FAM19036-p1-1.1_002047 1171373.PACID_09960 4.5e-106 390.6 Propionibacteriales pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 2GKCV@201174,4DPFB@85009,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis gnl|extdb|FAM19036-p1-1.1_002048 1171373.PACID_09950 1.5e-101 375.6 Propionibacteriales ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2GJPJ@201174,4DQEY@85009,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance gnl|extdb|FAM19036-p1-1.1_002049 1171373.PACID_09940 7.3e-175 619.8 Propionibacteriales prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ9S@201174,4DP73@85009,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) gnl|extdb|FAM19036-p1-1.1_002050 1122997.AUDD01000023_gene1430 1.4e-254 885.2 Propionibacteriales glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528,ko:K16203 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko01002 3.A.1.5.2 iJN678.glmU,iLJ478.TM1629 Bacteria 2GJS1@201174,4DNA1@85009,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain gnl|extdb|FAM19036-p1-1.1_002053 1171373.PACID_09900 4.6e-91 340.5 Propionibacteriales pecS Bacteria 2GJ6W@201174,4DQK5@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM19036-p1-1.1_002054 1171373.PACID_09890 1.9e-159 568.5 Propionibacteriales ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 2GKXD@201174,4DPS0@85009,COG1947@1,COG1947@2 NA|NA|NA I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol gnl|extdb|FAM19036-p1-1.1_002055 1171373.PACID_09880 1.9e-150 538.5 Propionibacteriales ksgA 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 2GKBT@201174,4DN5S@85009,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits gnl|extdb|FAM19036-p1-1.1_002056 1171373.PACID_09870 4.5e-163 580.5 Propionibacteriales tatD ko:K03424 ko00000,ko01000 Bacteria 2GMJJ@201174,4DPJ5@85009,COG0084@1,COG0084@2 NA|NA|NA L TatD related DNase gnl|extdb|FAM19036-p1-1.1_002057 1171373.PACID_09860 2.2e-151 541.6 Propionibacteriales rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 2GJ9Q@201174,4DN3D@85009,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA gnl|extdb|FAM19036-p1-1.1_002059 1171373.PACID_09840 2.7e-277 960.7 Propionibacteriales rutG GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082 ko:K02824,ko:K09016 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.1.3 iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189 Bacteria 2GMH6@201174,4DP9E@85009,COG2233@1,COG2233@2 NA|NA|NA F Permease family gnl|extdb|FAM19036-p1-1.1_002060 1171373.PACID_09830 8e-219 766.1 Propionibacteriales Bacteria 2GJQK@201174,4DPFW@85009,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase gnl|extdb|FAM19036-p1-1.1_002061 1171373.PACID_09820 1.3e-287 995.0 Propionibacteriales ybgK Bacteria 2GITH@201174,4DQVB@85009,COG1984@1,COG1984@2,COG2049@1,COG2049@2 NA|NA|NA E Allophanate hydrolase subunit 2 gnl|extdb|FAM19036-p1-1.1_002062 1171373.PACID_09810 2.7e-121 441.4 Propionibacteriales lamB ko:K07160 ko00000 Bacteria 2GJA1@201174,4DQF0@85009,COG1540@1,COG1540@2 NA|NA|NA S Belongs to the UPF0271 (lamB) family gnl|extdb|FAM19036-p1-1.1_002063 1171373.PACID_09800 1.6e-294 1018.1 Actinobacteria Bacteria 2GN91@201174,COG3044@1,COG3044@2 NA|NA|NA T ATPase of the ABC class gnl|extdb|FAM19036-p1-1.1_002064 1171373.PACID_09790 3.8e-25 120.2 Bacteria csbD Bacteria COG3237@1,COG3237@2 NA|NA|NA K CsbD-like gnl|extdb|FAM19036-p1-1.1_002065 1171373.PACID_09780 6.4e-106 390.2 Actinobacteria Bacteria 2DBAJ@1,2IFGB@201174,2Z83A@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002066 1171373.PACID_09770 2.2e-243 847.8 Actinobacteria Bacteria 2H4CN@201174,COG1020@1,COG1020@2 NA|NA|NA Q D-alanine [D-alanyl carrier protein] ligase activity gnl|extdb|FAM19036-p1-1.1_002067 1171373.PACID_09760 4.9e-187 660.2 Actinobacteria ko:K01066 ko00000,ko01000 Bacteria 2I6Z1@201174,COG0657@1,COG0657@2 NA|NA|NA I Esterase gnl|extdb|FAM19036-p1-1.1_002068 1171373.PACID_09750 8.9e-229 799.3 Propionibacteriales Bacteria 2GIXR@201174,4DNF6@85009,COG4585@1,COG4585@2 NA|NA|NA T Putative sensor gnl|extdb|FAM19036-p1-1.1_002069 1171373.PACID_09740 6.4e-111 406.8 Propionibacteriales Bacteria 2GM61@201174,4DQBV@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_002070 1171373.PACID_09730 3.1e-184 651.0 Propionibacteriales gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJK4@201174,4DNQ8@85009,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gnl|extdb|FAM19036-p1-1.1_002071 1171373.PACID_09720 2.9e-97 361.3 Actinobacteria Bacteria 2HX7D@201174,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002072 1171373.PACID_09710 3e-32 144.1 Bacteria Bacteria COG3548@1,COG3548@2 NA|NA|NA S protein homotetramerization gnl|extdb|FAM19036-p1-1.1_002073 1171373.PACID_09710 2.2e-57 228.0 Bacteria Bacteria COG3548@1,COG3548@2 NA|NA|NA S protein homotetramerization gnl|extdb|FAM19036-p1-1.1_002074 1171373.PACID_09700 5e-96 357.1 Propionibacteriales 3.5.1.124 ko:K05520 ko00000,ko01000,ko01002 Bacteria 2GMMW@201174,4DRYP@85009,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family gnl|extdb|FAM19036-p1-1.1_002076 1171373.PACID_09680 1.2e-167 595.9 Actinobacteria Bacteria 2GMKH@201174,COG0789@1,COG0789@2,COG1413@1,COG1413@2 NA|NA|NA CK transcriptional gnl|extdb|FAM19036-p1-1.1_002077 1171373.PACID_09670 3.2e-113 414.5 Propionibacteriales 4.4.1.32 ko:K02289 ko00196,ko01100,map00196,map01100 ko00000,ko00001,ko00194,ko01000 Bacteria 2GITU@201174,4DVW4@85009,COG1413@1,COG1413@2 NA|NA|NA C HEAT repeats gnl|extdb|FAM19036-p1-1.1_002078 1171373.PACID_09660 1.7e-85 322.0 Actinobacteria Bacteria 2IDXB@201174,COG1309@1,COG1309@2 NA|NA|NA K Bacterial transcriptional repressor C-terminal gnl|extdb|FAM19036-p1-1.1_002079 1171373.PACID_09650 3.3e-217 760.8 Propionibacteriales kasA GO:0001666,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009628,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019367,GO:0019752,GO:0030312,GO:0030497,GO:0032787,GO:0034645,GO:0036293,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0070482,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.3.1.179 ko:K09458,ko:K11609 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GIY4@201174,4DN2J@85009,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP gnl|extdb|FAM19036-p1-1.1_002080 1171373.PACID_09640 7.4e-163 579.7 Propionibacteriales ko:K09164 ko00000 Bacteria 2GK08@201174,4DRRS@85009,COG3358@1,COG3358@2 NA|NA|NA S Protein of unknown function (DUF1684) gnl|extdb|FAM19036-p1-1.1_002082 1171373.PACID_09620 0.0 1104.0 Propionibacteriales 1.3.99.4 ko:K05898 ko00984,ko01100,ko01120,map00984,map01100,map01120 R09884 RC00991 ko00000,ko00001,ko01000 Bacteria 2GIXG@201174,4DP1I@85009,COG1053@1,COG1053@2 NA|NA|NA C catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione gnl|extdb|FAM19036-p1-1.1_002083 1171373.PACID_09610 4.1e-189 667.2 Actinobacteria Bacteria 2I8ND@201174,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase gnl|extdb|FAM19036-p1-1.1_002084 1171373.PACID_09600 8.6e-51 206.1 Actinobacteria Bacteria 2IQ55@201174,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002085 1171373.PACID_09590 6.1e-151 540.0 Propionibacteriales ko:K21006 ko02025,map02025 ko00000,ko00001 Bacteria 2GM86@201174,4DQKQ@85009,COG3868@1,COG3868@2 NA|NA|NA S Glycoside-hydrolase family GH114 gnl|extdb|FAM19036-p1-1.1_002087 1171373.PACID_09570 0.0 2126.3 Propionibacteriales helZ 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2GISC@201174,4DT04@85009,COG0553@1,COG0553@2,COG4715@1,COG4715@2 NA|NA|NA KL SNF2 family N-terminal domain gnl|extdb|FAM19036-p1-1.1_002088 1171373.PACID_09560 9e-121 439.5 Propionibacteriales GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 Bacteria 2IQW2@201174,4DRJD@85009,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_002089 1171373.PACID_09550 1.7e-146 525.4 Propionibacteriales Bacteria 2GMPU@201174,4DS3N@85009,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM19036-p1-1.1_002090 1171373.PACID_09540 1.4e-215 755.4 Propionibacteriales aspB Bacteria 2GJ7R@201174,4DPVC@85009,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II gnl|extdb|FAM19036-p1-1.1_002092 1171373.PACID_03410 1.9e-197 694.9 Propionibacteriales Bacteria 2IAHV@201174,4DUEP@85009,COG3335@1,COG3335@2,COG3415@1,COG3415@2 NA|NA|NA L Winged helix-turn helix gnl|extdb|FAM19036-p1-1.1_002093 1151122.AQYD01000005_gene3673 5.5e-105 387.5 Microbacteriaceae ubiA 2.5.1.133,2.5.1.62 ko:K04040 ko00860,ko01100,ko01110,map00860,map01100,map01110 R06284,R09067,R11514,R11517 RC00020 ko00000,ko00001,ko01000,ko01006 Bacteria 2GKJ2@201174,4FKV3@85023,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family gnl|extdb|FAM19036-p1-1.1_002095 1194165.CAJF01000007_gene566 3e-22 111.3 Microbacteriaceae crtYe ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2GQFT@201174,4FQ7G@85023,COG3266@1,COG3266@2 NA|NA|NA S lycopene cyclase gnl|extdb|FAM19036-p1-1.1_002096 1194165.CAJF01000007_gene567 5.5e-185 654.1 Microbacteriaceae crtI 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 ko:K10027,ko:K20611 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 2GJAV@201174,4FMBC@85023,COG1233@1,COG1233@2 NA|NA|NA Q Flavin containing amine oxidoreductase gnl|extdb|FAM19036-p1-1.1_002097 1194165.CAJF01000007_gene568 1.5e-78 299.7 Microbacteriaceae crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 ko:K00801,ko:K02291,ko:K10208 ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130 M00097 R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177 RC00362,RC00796,RC01101,RC02839,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2I4YZ@201174,4FM0D@85023,COG1562@1,COG1562@2 NA|NA|NA I Squalene/phytoene synthase gnl|extdb|FAM19036-p1-1.1_002100 714083.JH370377_gene1449 1.4e-41 176.0 Microbacteriaceae Bacteria 2IRM4@201174,4FS9R@85023,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM19036-p1-1.1_002101 1122175.ATXU01000009_gene1835 4.4e-50 204.1 Microbacteriaceae Bacteria 2IM15@201174,3195F@2,4FP9Z@85023,arCOG05276@1 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002102 1416752.AYME01000019_gene39 8.7e-224 783.5 Microbacteriaceae ko:K06994 ko00000 Bacteria 2GIRQ@201174,4FK9T@85023,COG2409@1,COG2409@2 NA|NA|NA S MMPL family gnl|extdb|FAM19036-p1-1.1_002104 1348338.ADILRU_2493 6.9e-19 100.5 Microbacteriaceae wcoO Bacteria 2IIZ2@201174,4FNV1@85023,COG1030@1,COG1030@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002106 1171373.PACID_03220 2.5e-247 860.9 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_002108 1171373.PACID_03300 2.5e-269 934.1 Propionibacteriales Bacteria 2GJUG@201174,4DU0T@85009,COG3385@1,COG3385@2 NA|NA|NA L Transposase DDE domain group 1 gnl|extdb|FAM19036-p1-1.1_002110 930171.Asphe3_22480 5.9e-141 506.9 Actinobacteria Bacteria 28JTD@1,2IB6M@201174,2Z9IP@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002111 1121933.AUHH01000008_gene1174 7.6e-256 889.4 Propionibacteriales Bacteria 2GM5W@201174,4DP1Q@85009,COG3451@1,COG3451@2 NA|NA|NA U Type IV secretory pathway, VirB4 gnl|extdb|FAM19036-p1-1.1_002112 1121933.AUHH01000008_gene1173 6.8e-77 293.5 Propionibacteriales Bacteria 29K3G@1,2IINK@201174,3070W@2,4DSVC@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002113 1121933.AUHH01000008_gene1172 0.0 1104.4 Propionibacteriales Bacteria 2GNQ7@201174,4DNM4@85009,COG3505@1,COG3505@2 NA|NA|NA U Type IV secretory pathway VirD4 gnl|extdb|FAM19036-p1-1.1_002114 1184609.KILIM_019_00520 1.6e-76 292.0 Actinobacteria ssb2 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2IMCN@201174,COG0629@1,COG0629@2 NA|NA|NA L single-stranded DNA binding gnl|extdb|FAM19036-p1-1.1_002116 930171.Asphe3_22540 5.3e-28 129.8 Actinobacteria Bacteria 2EBC3@1,2GUEZ@201174,335CU@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002119 1122997.AUDD01000021_gene2209 7.8e-111 407.1 Actinobacteria Bacteria 2HD2H@201174,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family gnl|extdb|FAM19036-p1-1.1_002122 1429046.RR21198_4301 9.4e-34 150.6 Actinobacteria 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2IPSX@201174,COG2357@1,COG2357@2 NA|NA|NA S Region found in RelA / SpoT proteins gnl|extdb|FAM19036-p1-1.1_002123 888050.HMPREF9004_1846 1.4e-09 68.9 Bacteria 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria COG2357@1,COG2357@2 NA|NA|NA S guanosine tetraphosphate metabolic process gnl|extdb|FAM19036-p1-1.1_002124 446469.Sked_16220 1.5e-08 66.6 Bacteria Bacteria 290BF@1,2ZN0Z@2 NA|NA|NA S Helix-turn-helix XRE-family like proteins gnl|extdb|FAM19036-p1-1.1_002133 714083.JH370377_gene1344 6.2e-50 204.5 Actinobacteria Bacteria 2E37I@1,2IKDS@201174,32Y78@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002134 29306.JOBE01000087_gene3937 6.7e-15 87.8 Actinobacteria ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GTDH@201174,COG0629@1,COG0629@2 NA|NA|NA L single-stranded DNA binding gnl|extdb|FAM19036-p1-1.1_002137 1410634.JHVD01000032_gene426 9.1e-41 172.9 Propionibacteriales Bacteria 2E0Z5@1,2IR2P@201174,32WFJ@2,4DVDC@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002147 1115632.JAFW01000001_gene424 2.4e-169 602.1 Actinobacteria dcm 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 2GJS2@201174,COG0270@1,COG0270@2 NA|NA|NA L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family gnl|extdb|FAM19036-p1-1.1_002154 281090.Lxx24020 1.2e-77 297.4 Microbacteriaceae Bacteria 2IB7D@201174,4FMQD@85023,COG4626@1,COG4626@2 NA|NA|NA S Terminase gnl|extdb|FAM19036-p1-1.1_002155 1122237.AUGQ01000016_gene2607 2.2e-141 509.6 Actinobacteria Bacteria 2I9PX@201174,COG4695@1,COG4695@2 NA|NA|NA S Phage portal protein gnl|extdb|FAM19036-p1-1.1_002156 1415166.NONO_c17790 8.8e-43 180.6 Nocardiaceae ko:K06904 ko00000 Bacteria 2IC7D@201174,4FZGZ@85025,COG3740@1,COG3740@2 NA|NA|NA S Caudovirus prohead serine protease gnl|extdb|FAM19036-p1-1.1_002157 640132.Srot_1164 3.5e-89 335.5 Actinobacteria xkdG Bacteria 2ICZP@201174,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family gnl|extdb|FAM19036-p1-1.1_002159 1120945.ATUW01000025_gene1202 3.8e-13 81.6 Actinobacteria Bacteria 28XFC@1,2IPP5@201174,2ZJCX@2,4D6W5@85005 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002163 994479.GL877878_gene3339 8.5e-34 150.6 Pseudonocardiales Bacteria 2ARPD@1,2HZMH@201174,31H05@2,4ECZG@85010 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002167 646529.Desaci_1311 4.1e-51 210.7 Clostridia Bacteria 1UHTF@1239,25ECD@186801,COG5280@1,COG5280@2 NA|NA|NA M Tail tape measure protein, TP901 family gnl|extdb|FAM19036-p1-1.1_002173 504553.B5LGB8_9CAUD 6.5e-92 344.0 Siphoviridae GO:0005575,GO:0018995,GO:0020002,GO:0033643,GO:0033644,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279 Viruses 4QAK6@10239,4QKKV@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidoglycan catabolic process gnl|extdb|FAM19036-p1-1.1_002179 1171373.PACID_09480 1.6e-140 505.4 Propionibacteriales Bacteria 2ETNC@1,2GKI3@201174,33M63@2,4DS5B@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002181 1171373.PACID_09460 3.4e-236 823.9 Propionibacteriales moeA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 2GJC3@201174,4DNAW@85009,COG0303@1,COG0303@2 NA|NA|NA H MoeA domain protein domain I and II gnl|extdb|FAM19036-p1-1.1_002183 1171373.PACID_09440 1.3e-34 152.1 Actinobacteria fmdB Bacteria 2IQHE@201174,COG2331@1,COG2331@2 NA|NA|NA S Regulatory protein, FmdB family gnl|extdb|FAM19036-p1-1.1_002184 1171373.PACID_09430 5.5e-72 277.3 Bacteria cpaB ko:K02279 ko00000,ko02035,ko02044 Bacteria COG3745@1,COG3745@2 NA|NA|NA U Flp pilus assembly protein CpaB gnl|extdb|FAM19036-p1-1.1_002185 1171373.PACID_09420 1.3e-55 222.2 Propionibacteriales mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 2IQDN@201174,4DRP7@85009,COG1970@1,COG1970@2 NA|NA|NA M Large-conductance mechanosensitive channel, MscL gnl|extdb|FAM19036-p1-1.1_002187 1171373.PACID_09400 4.5e-266 923.3 Propionibacteriales ugp 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2G3@201174,4DPKI@85009,COG4284@1,COG4284@2 NA|NA|NA G UTP--glucose-1-phosphate uridylyltransferase gnl|extdb|FAM19036-p1-1.1_002188 1171373.PACID_02680 2.2e-229 801.2 Actinobacteria Bacteria 2I8Z0@201174,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives gnl|extdb|FAM19036-p1-1.1_002190 1171373.PACID_09380 5.5e-178 630.2 Propionibacteriales idhA 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2H22V@201174,4DWKJ@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM19036-p1-1.1_002192 1171373.PACID_09360 5.9e-235 819.7 Actinobacteria Bacteria 2GK0F@201174,COG0673@1,COG0673@2 NA|NA|NA E oxidoreductase gnl|extdb|FAM19036-p1-1.1_002195 1171373.PACID_09330 0.0 1265.8 Propionibacteriales iolD GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 R08603 RC02331 ko00000,ko00001,ko01000 iYO844.BSU39730 Bacteria 2GMCJ@201174,4DQ59@85009,COG3962@1,COG3962@2 NA|NA|NA E Thiamine pyrophosphate enzyme, central domain gnl|extdb|FAM19036-p1-1.1_002196 1171373.PACID_09320 1.2e-173 615.5 Propionibacteriales iolB 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 R08503 RC00541 ko00000,ko00001,ko01000 Bacteria 2GM8S@201174,4DQKK@85009,COG3718@1,COG3718@2 NA|NA|NA G KduI/IolB family gnl|extdb|FAM19036-p1-1.1_002197 1171373.PACID_09310 8.7e-159 566.2 Propionibacteriales Bacteria 2GKTN@201174,4DN9P@85009,COG1830@1,COG1830@2 NA|NA|NA G deoxyribose-phosphate aldolase gnl|extdb|FAM19036-p1-1.1_002198 1171373.PACID_09300 2.5e-186 657.9 Propionibacteriales iolC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 R05661 RC00002,RC00017 ko00000,ko00001,ko01000 iYO844.BSU39740 Bacteria 2GM3N@201174,4DNFD@85009,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM19036-p1-1.1_002199 1171373.PACID_09290 1.3e-209 735.3 Propionibacteriales tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMF9@201174,4DTCS@85009,COG0176@1,COG0176@2 NA|NA|NA H Transaldolase/Fructose-6-phosphate aldolase gnl|extdb|FAM19036-p1-1.1_002201 1171373.PACID_09270 6.2e-154 550.1 Propionibacteriales ko:K13611,ko:K15676 ko00000,ko01004,ko01008 Bacteria 2IBQJ@201174,4DR85@85009,COG0500@1,COG2226@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family gnl|extdb|FAM19036-p1-1.1_002202 1171373.PACID_09260 8.3e-128 463.0 Propionibacteriales ideR GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356,ko:K03709 M00729 ko00000,ko00002,ko01000,ko01002,ko03000,ko03400 Bacteria 2GKMC@201174,4DP20@85009,COG1321@1,COG1321@2 NA|NA|NA K Helix-turn-helix diphteria tox regulatory element gnl|extdb|FAM19036-p1-1.1_002203 1171373.PACID_09250 1.3e-212 745.3 Propionibacteriales nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 iNJ661.Rv3332 Bacteria 2GK1E@201174,4DPBF@85009,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family gnl|extdb|FAM19036-p1-1.1_002204 1171373.PACID_09240 1.1e-211 742.3 Propionibacteriales serC GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKYK@201174,4DP4I@85009,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine gnl|extdb|FAM19036-p1-1.1_002206 1032480.MLP_46170 2.7e-35 155.6 Bacteria Bacteria 2DXQJ@1,34615@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002208 1171373.PACID_09190 3.2e-42 177.6 Bacteria Bacteria 2DCEY@1,2ZDVV@2 NA|NA|NA S Protein of unknown function (DUF2530) gnl|extdb|FAM19036-p1-1.1_002209 1171373.PACID_09180 1.7e-159 568.5 Propionibacteriales Bacteria 28NWB@1,2GJ74@201174,2ZBU7@2,4DQ8F@85009 NA|NA|NA S Protein of unknown function (DUF3027) gnl|extdb|FAM19036-p1-1.1_002210 1171373.PACID_09170 1.4e-65 255.4 Propionibacteriales cspB ko:K03704 ko00000,ko03000 Bacteria 2IKXN@201174,4DQZ2@85009,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain gnl|extdb|FAM19036-p1-1.1_002211 1171373.PACID_09160 1.3e-142 512.3 Propionibacteriales nagB 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK7F@201174,4DN4K@85009,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion gnl|extdb|FAM19036-p1-1.1_002213 1171373.PACID_09140 0.0 1358.2 Propionibacteriales Bacteria 2GURQ@201174,4DP0U@85009,COG2378@1,COG2378@2 NA|NA|NA K Helicase conserved C-terminal domain gnl|extdb|FAM19036-p1-1.1_002214 1171373.PACID_09130 0.0 1100.5 Propionibacteriales ercc3 3.6.4.12 ko:K10843 ko03022,ko03420,map03022,map03420 M00290 ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GIR9@201174,4DNIW@85009,COG1061@1,COG1061@2 NA|NA|NA L ERCC3/RAD25/XPB C-terminal helicase gnl|extdb|FAM19036-p1-1.1_002215 1171373.PACID_09120 5.2e-127 460.3 Propionibacteriales cutC ko:K06201 ko00000 Bacteria 2GKI8@201174,4DQWU@85009,COG3142@1,COG3142@2 NA|NA|NA P CutC family gnl|extdb|FAM19036-p1-1.1_002218 1171373.PACID_09080 5.9e-98 363.6 Propionibacteriales oprF ko:K03640 ko00000,ko02000 2.C.1.2 Bacteria 2HJR3@201174,4DWEB@85009,COG2885@1,COG2885@2 NA|NA|NA M OmpA family gnl|extdb|FAM19036-p1-1.1_002219 1171373.PACID_09070 9.1e-183 646.0 Propionibacteriales Bacteria 2I47R@201174,4DX0K@85009,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002220 1171373.PACID_09060 2.3e-290 1004.2 Propionibacteriales groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2GKC9@201174,4DNNQ@85009,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions gnl|extdb|FAM19036-p1-1.1_002222 1171373.PACID_09040 6.9e-228 796.2 Propionibacteriales manA GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,5.3.1.8,5.4.2.8 ko:K01809,ko:K01840,ko:K04035 ko00051,ko00520,ko00860,ko01100,ko01110,ko01130,map00051,map00520,map00860,map01100,map01110,map01130 M00114 R01818,R01819,R06265,R06266,R06267,R10068 RC00376,RC00408,RC00741,RC01491,RC01492,RC03042 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801 Bacteria 2GJXC@201174,4DPWV@85009,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase, class I gnl|extdb|FAM19036-p1-1.1_002223 1171373.PACID_09020 2.3e-86 324.7 Actinobacteria luxS GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJVF@201174,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) gnl|extdb|FAM19036-p1-1.1_002228 1122997.AUDD01000018_gene2299 8e-165 587.0 Actinobacteria 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2IAGX@201174,COG0467@1,COG0467@2 NA|NA|NA LT AAA domain gnl|extdb|FAM19036-p1-1.1_002236 1122997.AUDD01000001_gene2417 2.7e-133 481.9 Propionibacteriales Bacteria 2HD2H@201174,4DUUF@85009,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase family gnl|extdb|FAM19036-p1-1.1_002238 1171373.PACID_09000 4.1e-141 507.3 Propionibacteriales Bacteria 2GM5T@201174,4DQPT@85009,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain gnl|extdb|FAM19036-p1-1.1_002239 1171373.PACID_08990 3.7e-145 520.8 Propionibacteriales fecB ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GYJE@201174,4DPCN@85009,COG0614@1,COG0614@2 NA|NA|NA P ABC-type Fe3 -hydroxamate transport system, periplasmic component gnl|extdb|FAM19036-p1-1.1_002241 1171373.PACID_08970 6.1e-105 386.7 Propionibacteriales cobU 2.4.2.21,2.7.1.156,2.7.7.62 ko:K00768,ko:K02231 ko00860,ko01100,map00860,map01100 M00122 R04148,R05221,R05222,R06558 RC00002,RC00033,RC00063,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM8Q@201174,4DQRD@85009,COG2087@1,COG2087@2 NA|NA|NA H Cobinamide kinase / cobinamide phosphate guanyltransferase gnl|extdb|FAM19036-p1-1.1_002242 1171373.PACID_08960 7.7e-200 703.0 Propionibacteriales cobT 2.4.2.21 ko:K00768 ko00860,ko01100,map00860,map01100 M00122 R04148 RC00033,RC00063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ16@201174,4DNBW@85009,COG2038@1,COG2038@2 NA|NA|NA H Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) gnl|extdb|FAM19036-p1-1.1_002243 1171373.PACID_08950 2.4e-130 471.5 Propionibacteriales cobK 1.3.1.106,1.3.1.54,1.3.1.76,2.1.1.131,2.1.1.132,3.7.1.12,4.99.1.4 ko:K00595,ko:K02304,ko:K05895,ko:K05934,ko:K13541 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947,R05149,R05150,R05180,R05809,R05812,R07772 RC00003,RC01012,RC01034,RC01279,RC01280,RC01293,RC01545,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMYZ@201174,4DPKR@85009,COG2099@1,COG2099@2 NA|NA|NA H reductase gnl|extdb|FAM19036-p1-1.1_002244 1171373.PACID_08940 1.9e-144 518.5 Propionibacteriales cysG GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.3,4.99.1.4 ko:K02302,ko:K02303,ko:K02304,ko:K03795,ko:K04719,ko:K13542 ko00740,ko00860,ko01100,ko01110,ko01120,map00740,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947,R05807,R09083 RC00003,RC00435,RC00871,RC01012,RC01034,RC01861,RC02413 ko00000,ko00001,ko00002,ko01000 iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158 Bacteria 2GK3B@201174,4DN4H@85009,COG0007@1,COG0007@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases gnl|extdb|FAM19036-p1-1.1_002245 1171373.PACID_08930 0.0 1696.4 Propionibacteriales cobB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.6.1.9,4.1.1.81,6.3.5.11,6.3.5.9 ko:K00817,ko:K02224,ko:K04720 ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01120,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01120,map01130,map01230 M00026 R00694,R00734,R03243,R05224,R05815,R06530 RC00006,RC00010,RC00517,RC00888,RC01301 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ3R@201174,4DN94@85009,COG0079@1,COG0079@2,COG1797@1,COG1797@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source gnl|extdb|FAM19036-p1-1.1_002246 1171373.PACID_08920 9.2e-115 419.5 Propionibacteriales cobO 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2849c Bacteria 2GNJQ@201174,4DNYI@85009,COG2109@1,COG2109@2 NA|NA|NA H ATP:corrinoid adenosyltransferase BtuR/CobO/CobP gnl|extdb|FAM19036-p1-1.1_002247 1171373.PACID_08910 7.2e-109 399.8 Propionibacteriales cobL 2.1.1.132 ko:K00595 ko00860,ko01100,map00860,map01100 R05149 RC00003,RC01279 ko00000,ko00001,ko01000 Bacteria 2GM8G@201174,4DNG6@85009,COG2242@1,COG2242@2 NA|NA|NA H Precorrin-6y C5,15-methyltransferase gnl|extdb|FAM19036-p1-1.1_002248 1171373.PACID_08900 3.8e-148 530.8 Propionibacteriales cbiO GO:0000041,GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006824,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0022857,GO:0030001,GO:0030554,GO:0031224,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072511,GO:0090482,GO:0097159,GO:0097367,GO:0098533,GO:0098656,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902494,GO:1902495,GO:1904949,GO:1990351 2.1.1.195 ko:K02006,ko:K02188,ko:K16786 ko00860,ko01100,ko02010,map00860,map01100,map02010 M00245,M00246,M00582 R07773 RC00003,RC02051 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4DN9V@85009,COG1122@1,COG1122@2 NA|NA|NA P Part of an ABC transporter complex. Responsible for energy coupling to the transport system gnl|extdb|FAM19036-p1-1.1_002249 1171373.PACID_08890 1e-145 522.7 Propionibacteriales cbiQ GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02008 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 2GP2M@201174,4DQAX@85009,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein gnl|extdb|FAM19036-p1-1.1_002250 1171373.PACID_08880 5.3e-72 276.9 Actinobacteria cbiN GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02009 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18 Bacteria 2GRJ6@201174,COG1930@1,COG1930@2 NA|NA|NA P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import gnl|extdb|FAM19036-p1-1.1_002251 1171373.PACID_08870 1e-128 466.1 Propionibacteriales cbiM GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02007 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 2GK2U@201174,4DNYF@85009,COG0310@1,COG0310@2 NA|NA|NA P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import gnl|extdb|FAM19036-p1-1.1_002252 1171373.PACID_08860 8.5e-111 406.4 Propionibacteriales cobH 1.7.7.1,2.1.1.130,2.1.1.151,5.4.99.60,5.4.99.61 ko:K00366,ko:K03394,ko:K06042 ko00860,ko00910,ko01100,ko01120,map00860,map00910,map01100,map01120 M00531 R00790,R03948,R05177,R05808,R05814 RC00003,RC00176,RC01035,RC01292,RC01662,RC01980 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK0B@201174,4DPQK@85009,COG2082@1,COG2082@2 NA|NA|NA H Precorrin-8X methylmutase gnl|extdb|FAM19036-p1-1.1_002253 1171373.PACID_08850 2.4e-153 548.1 Actinobacteria Bacteria 2FC2C@1,2H4PU@201174,3446A@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002254 1171373.PACID_08840 5.9e-236 823.2 Propionibacteriales cysG GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,2.1.1.131,3.7.1.12,4.99.1.3,4.99.1.4 ko:K02006,ko:K02302,ko:K02303,ko:K02304,ko:K03794,ko:K03795,ko:K13541 ko00860,ko01100,ko01110,ko01120,ko02010,map00860,map01100,map01110,map01120,map02010 M00121,M00245,M00246 R02864,R03194,R03947,R05180,R05807,R05809,R07772 RC00003,RC00871,RC01012,RC01034,RC01293,RC01545,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158 Bacteria 2GS51@201174,4DWKH@85009,COG1648@1,COG1648@2,COG2138@1,COG2138@2 NA|NA|NA H Putative NAD(P)-binding gnl|extdb|FAM19036-p1-1.1_002255 1171373.PACID_08830 0.0 1618.6 Propionibacteriales cobJ 2.1.1.131,2.1.1.132,2.1.1.133,2.1.1.271,2.6.1.9,3.7.1.12 ko:K00595,ko:K00817,ko:K02189,ko:K05936,ko:K13541 ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243,R05149,R05180,R05181,R05809,R05810,R07772 RC00003,RC00006,RC00888,RC01279,RC01293,RC01294,RC01545,RC02049,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GMIR@201174,4DPRG@85009,COG1010@1,COG1010@2,COG2073@1,COG2073@2,COG2241@1,COG2241@2 NA|NA|NA H precorrin-3B C17-methyltransferase gnl|extdb|FAM19036-p1-1.1_002256 1171373.PACID_08820 1.7e-159 568.5 Propionibacteriales cobM 1.3.1.76,2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,4.99.1.4 ko:K02304,ko:K05936,ko:K13541 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947,R05180,R05181,R05809,R05810,R07772 RC00003,RC01012,RC01034,RC01293,RC01294,RC01545,RC02049,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ97@201174,4DPG8@85009,COG2875@1,COG2875@2 NA|NA|NA H Belongs to the precorrin methyltransferase family gnl|extdb|FAM19036-p1-1.1_002257 1171373.PACID_08810 4.8e-129 467.2 Actinobacteria cobI 2.1.1.130,2.1.1.151,2.1.1.152 ko:K02228,ko:K03394 ko00860,ko01100,map00860,map01100 R03948,R05219,R05808 RC00003,RC00923,RC01035,RC01662,RC02890 ko00000,ko00001,ko01000 Bacteria 2GUI0@201174,COG2243@1,COG2243@2 NA|NA|NA H Precorrin-2 C(20)-methyltransferase gnl|extdb|FAM19036-p1-1.1_002258 1171373.PACID_08800 8.7e-281 972.2 Propionibacteriales cobQ GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS15780,iJN678.cbiP,iYL1228.KPN_03184 Bacteria 2GJ1W@201174,4DPU3@85009,COG1492@1,COG1492@2 NA|NA|NA H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation gnl|extdb|FAM19036-p1-1.1_002259 1171373.PACID_08790 7.2e-189 666.4 Propionibacteriales cobD 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMB8@201174,4DNIT@85009,COG1270@1,COG1270@2 NA|NA|NA H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group gnl|extdb|FAM19036-p1-1.1_002261 1171373.PACID_08770 1e-205 722.6 Propionibacteriales Bacteria 2GNBG@201174,4DPJ2@85009,COG4585@1,COG4585@2 NA|NA|NA T histidine kinase, dimerisation and phosphoacceptor region gnl|extdb|FAM19036-p1-1.1_002262 1171373.PACID_08760 1.3e-134 485.7 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJDP@201174,4DPR9@85009,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM19036-p1-1.1_002263 1171373.PACID_08750 1.1e-139 502.7 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2INE4@201174,4DNYD@85009,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component gnl|extdb|FAM19036-p1-1.1_002264 146922.JOFU01000015_gene3714 4.6e-08 63.9 Actinobacteria Bacteria 2DU45@1,2GPBC@201174,33NVP@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002265 1171373.PACID_08740 9.9e-103 379.4 Actinobacteria 3.1.3.85,5.4.2.11,5.4.2.12 ko:K01834,ko:K15634,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2IN3J@201174,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family gnl|extdb|FAM19036-p1-1.1_002266 1171373.PACID_08730 9.1e-156 556.2 Propionibacteriales folP2 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJNI@201174,4DNDN@85009,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives gnl|extdb|FAM19036-p1-1.1_002267 1171373.PACID_08720 1e-102 379.4 Propionibacteriales tcsR2 ko:K07693 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko02022 Bacteria 2GJ9U@201174,4DQ4U@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_002268 1171373.PACID_08710 1.3e-178 632.5 Propionibacteriales 2.7.13.3 ko:K07778 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GKRM@201174,4DPQ8@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_002269 1171373.PACID_08700 9.5e-130 469.5 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GK5F@201174,4DT7W@85009,COG0842@1,COG0842@2 NA|NA|NA V Abc-2 type transporter gnl|extdb|FAM19036-p1-1.1_002270 1171373.PACID_08690 3.8e-137 494.2 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJ0Y@201174,4DNFU@85009,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter gnl|extdb|FAM19036-p1-1.1_002271 1171373.PACID_08680 5.5e-76 290.4 Actinobacteria ymdB Bacteria 2IFEC@201174,COG2110@1,COG2110@2 NA|NA|NA S domain protein gnl|extdb|FAM19036-p1-1.1_002272 1171373.PACID_08670 2.6e-136 491.5 Propionibacteriales Bacteria 2IP88@201174,4DVGS@85009,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein gnl|extdb|FAM19036-p1-1.1_002274 1171373.PACID_08650 2e-194 684.9 Propionibacteriales tdh GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 ko:K00060 ko00260,map00260 R01465 RC00525 ko00000,ko00001,ko01000 iEC042_1314.EC042_3926,iECUMN_1333.ECUMN_4133,iPC815.YPO0060 Bacteria 2GKC7@201174,4DPQ5@85009,COG1063@1,COG1063@2 NA|NA|NA C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate gnl|extdb|FAM19036-p1-1.1_002276 1122997.AUDD01000010_gene713 2.2e-176 624.8 Propionibacteriales ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria 2GKBJ@201174,4DTXE@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002277 1171373.PACID_08620 1.9e-250 871.3 Propionibacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GNJW@201174,4DSCB@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_002278 1122997.AUDD01000010_gene715 0.0 1511.1 Propionibacteriales priA ko:K02565,ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 2GJNE@201174,4DQ3F@85009,COG0673@1,COG0673@2,COG1940@1,COG1940@2,COG2512@1,COG2512@2 NA|NA|NA GK Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM19036-p1-1.1_002279 1171373.PACID_08600 2.6e-277 960.7 Propionibacteriales sdaA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 2GJPA@201174,4DPVP@85009,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain gnl|extdb|FAM19036-p1-1.1_002280 1171373.PACID_08590 5.4e-166 590.1 Propionibacteriales 3.1.4.55 ko:K06167 ko00440,map00440 R10205 RC00296 ko00000,ko00001,ko01000 Bacteria 2I5W8@201174,4DVCM@85009,COG1235@1,COG1235@2 NA|NA|NA S Beta-lactamase superfamily domain gnl|extdb|FAM19036-p1-1.1_002281 1171373.PACID_08580 9.3e-107 392.9 Bacteria pgmB 3.1.3.18,5.4.2.6 ko:K01091,ko:K01838 ko00500,ko00630,ko01100,ko01110,ko01130,map00500,map00630,map01100,map01110,map01130 R01334,R02728,R11310 RC00017,RC00408 ko00000,ko00001,ko01000 Bacteria COG0637@1,COG0637@2 NA|NA|NA S phosphonoacetaldehyde hydrolase activity gnl|extdb|FAM19036-p1-1.1_002282 1171373.PACID_08570 1.2e-105 389.0 Actinobacteria 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2IJNS@201174,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_002283 1171373.PACID_08560 2.2e-280 971.1 Propionibacteriales Bacteria 2GIUM@201174,4DPK1@85009,COG0477@1,COG0477@2 NA|NA|NA P major facilitator superfamily gnl|extdb|FAM19036-p1-1.1_002285 1171373.PACID_08530 1.9e-203 714.9 Propionibacteriales msiK ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 2GJCM@201174,4DN4V@85009,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily gnl|extdb|FAM19036-p1-1.1_002286 1171373.PACID_08520 7.1e-172 609.8 Bacteria Bacteria COG2852@1,COG2852@2 NA|NA|NA L Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002287 1171373.PACID_08510 5.6e-58 231.5 Actinobacteria Bacteria 2I4F1@201174,COG3103@1,COG4991@2 NA|NA|NA T sh3 domain protein gnl|extdb|FAM19036-p1-1.1_002289 1171373.PACID_08490 6e-80 304.3 Propionibacteriales tagH 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01081,ko:K01119 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 2I3RJ@201174,4DR7V@85009,COG3103@1,COG3103@2 NA|NA|NA T sh3 domain protein gnl|extdb|FAM19036-p1-1.1_002290 1171373.PACID_08480 2.3e-100 371.7 Bacteria Bacteria 2EN49@1,33FSC@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002291 1171373.PACID_08470 4.6e-164 583.9 Actinobacteria Bacteria 2I77K@201174,COG1302@1,COG1302@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002292 1170318.PALO_08675 2.4e-10 70.9 Bacteria Bacteria 2EN1U@1,33FQ1@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002293 1171373.PACID_08450 2.2e-91 341.7 Propionibacteriales Bacteria 2IMA3@201174,4DSM4@85009,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function gnl|extdb|FAM19036-p1-1.1_002295 1171373.PACID_08430 1.8e-246 858.2 Propionibacteriales inaA ko:K02848 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2GIX0@201174,4DNTH@85009,COG3642@1,COG3642@2 NA|NA|NA T Domain of unknown function (DUF4032) gnl|extdb|FAM19036-p1-1.1_002297 1171373.PACID_08410 1.6e-282 978.0 Propionibacteriales cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJF2@201174,4DP8C@85009,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family gnl|extdb|FAM19036-p1-1.1_002298 1171373.PACID_08400 1.2e-172 612.5 Propionibacteriales rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJMR@201174,4DNYC@85009,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gnl|extdb|FAM19036-p1-1.1_002299 1171373.PACID_08390 9.5e-125 453.0 Actinobacteria Bacteria 2HWAV@201174,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase gnl|extdb|FAM19036-p1-1.1_002300 1171373.PACID_08380 9.1e-199 699.5 Propionibacteriales ygaY Bacteria 2GMWE@201174,4DUZN@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002301 1171373.PACID_08340 2e-280 971.1 Propionibacteriales glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK7U@201174,4DPXC@85009,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism gnl|extdb|FAM19036-p1-1.1_002303 1171373.PACID_08320 6.1e-297 1026.2 Propionibacteriales yciQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GNW7@201174,4DPRX@85009,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) gnl|extdb|FAM19036-p1-1.1_002304 1171373.PACID_08310 1.1e-164 586.6 Propionibacteriales ko:K07054 ko00000 Bacteria 2H3UT@201174,4DS8D@85009,COG2321@1,COG2321@2 NA|NA|NA S Putative neutral zinc metallopeptidase gnl|extdb|FAM19036-p1-1.1_002305 1171373.PACID_08300 1.1e-87 329.3 Propionibacteriales ispF GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.1.1.228,2.7.7.60,4.6.1.12 ko:K00554,ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05633,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iNJ661.Rv3581c Bacteria 2II8H@201174,4DQIJ@85009,COG0245@1,COG0245@2 NA|NA|NA I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) gnl|extdb|FAM19036-p1-1.1_002306 1171373.PACID_08290 1.1e-131 476.1 Propionibacteriales ispD GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNHP@201174,4DS1C@85009,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) gnl|extdb|FAM19036-p1-1.1_002307 1122998.AUHZ01000006_gene736 2.4e-82 312.0 Actinobacteria tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2IK9F@201174,COG0149@1,COG0149@2 NA|NA|NA G triose-phosphate isomerase activity gnl|extdb|FAM19036-p1-1.1_002308 1171373.PACID_08170 1.8e-170 605.1 Actinobacteria ko:K05346 ko00000,ko03000 Bacteria 2GMIM@201174,COG2390@1,COG2390@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002309 1171373.PACID_08150 2.1e-199 701.4 Actinobacteria gpsA 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJSD@201174,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase gnl|extdb|FAM19036-p1-1.1_002310 1171373.PACID_08140 1.4e-44 185.3 Actinobacteria 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 Bacteria 2GQN9@201174,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit gnl|extdb|FAM19036-p1-1.1_002311 1171373.PACID_08130 4.6e-277 959.9 Actinobacteria ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 Bacteria 2IBG5@201174,COG3775@1,COG3775@2 NA|NA|NA G PTS system Galactitol-specific IIC component gnl|extdb|FAM19036-p1-1.1_002313 1171373.PACID_08110 4e-78 297.4 Bacteria gatA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015791,GO:0015796,GO:0015850,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090584 2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K03491 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279 R03232,R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1 iECIAI39_1322.ECIAI39_0923 Bacteria COG1762@1,COG1762@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system gnl|extdb|FAM19036-p1-1.1_002314 1171373.PACID_08100 8.9e-81 306.2 Propionibacteriales carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K07736 ko00000,ko03000 Bacteria 2GKSU@201174,4DN6V@85009,COG1329@1,COG1329@2 NA|NA|NA K CarD-like/TRCF domain gnl|extdb|FAM19036-p1-1.1_002315 1171373.PACID_08080 2.1e-68 265.4 Propionibacteriales Bacteria 2E56G@1,2GX1H@201174,32ZZ6@2,4DSRT@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002316 1171373.PACID_08070 1.4e-121 442.2 Propionibacteriales Bacteria 2GKFS@201174,4DNN6@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM19036-p1-1.1_002318 1171373.PACID_08050 1.6e-117 428.7 Propionibacteriales phoU ko:K02039 ko00000 Bacteria 2GKAD@201174,4DQEB@85009,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake gnl|extdb|FAM19036-p1-1.1_002319 1171373.PACID_08040 2.3e-144 518.1 Propionibacteriales gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GK8F@201174,4DND2@85009,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gnl|extdb|FAM19036-p1-1.1_002320 1171373.PACID_08030 2.3e-38 164.5 Actinobacteria ptsH ko:K03488,ko:K11189 ko00000,ko02000,ko03000 4.A.2.1 Bacteria 2GQX6@201174,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein hpr gnl|extdb|FAM19036-p1-1.1_002322 1171373.PACID_08010 1.3e-134 485.7 Propionibacteriales Bacteria 2GMGQ@201174,4DPFM@85009,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM19036-p1-1.1_002323 1171373.PACID_08000 4.9e-23 114.0 Actinobacteria yngHB 2.1.3.1,6.4.1.1 ko:K01958,ko:K02160,ko:K17490 ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230 M00082,M00173,M00376 R00344,R00353,R00742 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 2I77H@201174,COG1038@1,COG1038@2 NA|NA|NA C Biotin-lipoyl like gnl|extdb|FAM19036-p1-1.1_002324 1171373.PACID_07990 2.9e-35 154.1 Bacteria 2.1.3.1 ko:K17489 ko00640,map00640 R00353 RC00040 ko00000,ko00001,ko01000 Bacteria 2EJZC@1,33DPX@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002325 1171373.PACID_07980 1.9e-297 1027.7 Actinobacteria mmdA 2.1.3.1,2.1.3.15,6.4.1.3 ko:K01966,ko:K17489 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R00353,R01859 RC00040,RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0716 Bacteria 2GIRU@201174,COG4799@1,COG4799@2 NA|NA|NA I Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta gnl|extdb|FAM19036-p1-1.1_002326 1171373.PACID_07970 7.5e-288 995.7 Propionibacteriales oadA 2.1.3.1,4.1.1.3,6.4.1.1 ko:K01571,ko:K01960,ko:K03416 ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00217,R00344,R00353,R00930 RC00040,RC00097,RC00367 ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 iLJ478.TM0128 Bacteria 2IASR@201174,4DWP1@85009,COG5016@1,COG5016@2 NA|NA|NA C Conserved carboxylase domain gnl|extdb|FAM19036-p1-1.1_002327 1171373.PACID_07960 1.2e-191 675.6 Propionibacteriales fbaA GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z4263 Bacteria 2GM5P@201174,4DPKE@85009,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class II gnl|extdb|FAM19036-p1-1.1_002330 1171373.PACID_07930 9.6e-138 496.1 Propionibacteriales dedA ko:K03975 ko00000 Bacteria 2GKGR@201174,4DQX9@85009,COG0586@1,COG0586@2 NA|NA|NA I SNARE associated Golgi protein gnl|extdb|FAM19036-p1-1.1_002331 1171373.PACID_07920 1.1e-54 219.9 Actinobacteria Bacteria 2EJKH@1,2IRVG@201174,33DBG@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002332 1171373.PACID_07910 0.0 2416.3 Propionibacteriales Bacteria 2GN7G@201174,4DP00@85009,COG3291@1,COG3291@2 NA|NA|NA S Repeats in polycystic kidney disease 1 (PKD1) and other proteins gnl|extdb|FAM19036-p1-1.1_002333 1171373.PACID_07900 1e-219 769.2 Actinobacteria Bacteria 2CD7Z@1,2GNGQ@201174,30EQS@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002334 1171373.PACID_07890 3.8e-260 903.7 Propionibacteriales wcoI 2.7.10.2 ko:K08253,ko:K16692 ko00000,ko01000,ko01001 Bacteria 2GJ1Y@201174,4DMYV@85009,COG0489@1,COG0489@2,COG3944@1,COG3944@2 NA|NA|NA DM AAA domain gnl|extdb|FAM19036-p1-1.1_002336 1171373.PACID_07870 0.0 1406.7 Propionibacteriales algG 3.2.1.4,5.1.3.37 ko:K01179,ko:K01795 ko00051,ko00500,ko01100,map00051,map00500,map01100 R06200,R08693,R11307,R11308 RC00509 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 2I9HA@201174,4DVEJ@85009,COG3291@1,COG3291@2,COG3420@1,COG3420@2 NA|NA|NA P Right handed beta helix region gnl|extdb|FAM19036-p1-1.1_002337 1171373.PACID_07860 4.2e-189 667.2 Actinobacteria gumI 2.4.1.251 ko:K13658 R09734 RC00005,RC00049 ko00000,ko01000,ko01003 Bacteria 2IAJJ@201174,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups gnl|extdb|FAM19036-p1-1.1_002338 1171373.PACID_07850 3.5e-108 397.9 Propionibacteriales Bacteria 2GNFE@201174,4DRZH@85009,COG0558@1,COG0558@2 NA|NA|NA I CDP-alcohol phosphatidyltransferase gnl|extdb|FAM19036-p1-1.1_002339 1171373.PACID_07840 2e-219 768.1 Actinobacteria wcoF Bacteria 2HAAS@201174,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 gnl|extdb|FAM19036-p1-1.1_002340 1171373.PACID_07830 1.3e-173 615.5 Bacteria 2.4.1.289 ko:K07011,ko:K16870 ko00000,ko01000,ko01003 Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 gnl|extdb|FAM19036-p1-1.1_002342 1171373.PACID_07810 6.9e-181 639.8 Actinobacteria Bacteria 2IG08@201174,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase, group 2 family protein gnl|extdb|FAM19036-p1-1.1_002344 1171373.PACID_07790 1.1e-120 439.5 Propionibacteriales ko:K03744 ko00000 Bacteria 2GPS4@201174,4DR1W@85009,COG1704@1,COG1704@2 NA|NA|NA S LemA family gnl|extdb|FAM19036-p1-1.1_002345 1171373.PACID_07780 3.5e-104 384.4 Bacteria srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria COG3764@1,COG3764@2 NA|NA|NA M Sortase family gnl|extdb|FAM19036-p1-1.1_002348 1171373.PACID_07750 2.4e-221 774.6 Actinobacteria aspB ko:K10907 ko00000,ko01000,ko01007 Bacteria 2GJ7R@201174,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM19036-p1-1.1_002349 1171373.PACID_07740 5.2e-292 1009.6 Propionibacteriales gbsA 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4DN0G@85009,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_002350 1171373.PACID_07730 0.0 1196.8 Propionibacteriales betA 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJAU@201174,4DP81@85009,COG2303@1,COG2303@2 NA|NA|NA C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate gnl|extdb|FAM19036-p1-1.1_002351 1171373.PACID_07720 3.2e-110 404.4 Actinobacteria ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GMQT@201174,COG1174@1,COG1174@2 NA|NA|NA E ABC transporter permease gnl|extdb|FAM19036-p1-1.1_002352 1171373.PACID_07710 8.5e-232 809.3 Actinobacteria opuCA ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iYO844.BSU33730 Bacteria 2GJHI@201174,COG0517@1,COG0517@2,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter gnl|extdb|FAM19036-p1-1.1_002353 1171373.PACID_07700 1.1e-120 439.5 Actinobacteria opuBB ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2H9I7@201174,COG1174@1,COG1174@2 NA|NA|NA E ABC-type proline glycine betaine transport systems, permease component gnl|extdb|FAM19036-p1-1.1_002354 1171373.PACID_07690 1.2e-183 649.0 Actinobacteria yehZ GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 ko:K05845 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iE2348C_1286.E2348C_2278,iEC55989_1330.EC55989_2381,iECIAI39_1322.ECIAI39_0865,iECO103_1326.ECO103_2607,iECSE_1348.ECSE_2399 Bacteria 2GJWY@201174,COG1732@1,COG1732@2 NA|NA|NA M Glycine betaine gnl|extdb|FAM19036-p1-1.1_002355 1171373.PACID_07680 2.7e-121 441.4 Actinobacteria Bacteria 29XMB@1,2IK48@201174,30JCK@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002356 1171373.PACID_07670 4.5e-166 590.5 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GRE8@201174,4DUEC@85009,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_002357 1171373.PACID_07660 1.6e-67 261.9 Propionibacteriales gntR1 ko:K07979 ko00000,ko03000 Bacteria 2IQKP@201174,4DVSI@85009,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor gnl|extdb|FAM19036-p1-1.1_002359 1292373.H640_04303 1.3e-122 446.0 Propionibacteriales proW ko:K02001,ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GKRF@201174,4DNV4@85009,COG4176@1,COG4176@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002362 1171373.PACID_05190 8.6e-64 250.0 Actinobacteria Bacteria 2II40@201174,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score gnl|extdb|FAM19036-p1-1.1_002363 1171373.PACID_33750 1.3e-44 186.4 Actinobacteria Bacteria 2II40@201174,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score gnl|extdb|FAM19036-p1-1.1_002364 1033736.CAHK01000059_gene433 9.9e-17 94.0 Brevibacteriaceae Bacteria 2IMGY@201174,4F940@85019,COG0515@1,COG0515@2 NA|NA|NA KLT Domain of unknown function (DUF4352) gnl|extdb|FAM19036-p1-1.1_002366 1171373.PACID_07560 0.0 1170.2 Actinobacteria Bacteria 2IBQ1@201174,COG0286@1,COG0286@2 NA|NA|NA V site-specific DNA-methyltransferase (adenine-specific) activity gnl|extdb|FAM19036-p1-1.1_002367 1171373.PACID_07550 2.7e-310 1070.5 Actinobacteria hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GKAQ@201174,COG0286@1,COG0286@2 NA|NA|NA V Type I restriction-modification system methyltransferase subunit gnl|extdb|FAM19036-p1-1.1_002368 479431.Namu_1103 6.5e-77 294.7 Frankiales 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 2IRWB@201174,4EU9U@85013,COG0732@1,COG0732@2 NA|NA|NA L Type I restriction modification DNA specificity domain gnl|extdb|FAM19036-p1-1.1_002369 1171373.PACID_07530 0.0 2020.0 Propionibacteriales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2HI69@201174,4DPUS@85009,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification gnl|extdb|FAM19036-p1-1.1_002370 1171373.PACID_07520 0.0 1720.7 Actinobacteria Bacteria 2IQVX@201174,COG5635@1,COG5635@2 NA|NA|NA T Nacht domain gnl|extdb|FAM19036-p1-1.1_002371 31964.CMS2187 5e-07 60.5 Actinobacteria Bacteria 2E8MQ@1,2H0MZ@201174,34A41@2 NA|NA|NA S Ribbon-helix-helix protein, copG family gnl|extdb|FAM19036-p1-1.1_002373 1171373.PACID_07480 5.2e-140 503.8 Propionibacteriales qorB 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 2GJB8@201174,4DQRI@85009,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family gnl|extdb|FAM19036-p1-1.1_002374 1171373.PACID_07470 7.5e-121 439.9 Propionibacteriales Bacteria 2GQPK@201174,4DR62@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002376 1171373.PACID_07450 3.9e-261 907.5 Propionibacteriales yhgE ko:K01421 ko00000 Bacteria 2GKEM@201174,4DQ2G@85009,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein gnl|extdb|FAM19036-p1-1.1_002377 1171373.PACID_07440 2.1e-85 321.6 Actinobacteria hsp20 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2IHVJ@201174,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family gnl|extdb|FAM19036-p1-1.1_002378 1171373.PACID_07430 4.2e-180 637.1 Propionibacteriales Bacteria 2I47R@201174,4DX0K@85009,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002379 1171373.PACID_07420 6.7e-251 872.8 Propionibacteriales celF 3.2.1.86 ko:K01222 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT4 Bacteria 2GK80@201174,4DQ21@85009,COG1486@1,COG1486@2 NA|NA|NA G Family 4 glycosyl hydrolase gnl|extdb|FAM19036-p1-1.1_002380 1171373.PACID_07410 3.3e-130 471.1 Propionibacteriales Bacteria 2GMAJ@201174,4DUHK@85009,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain gnl|extdb|FAM19036-p1-1.1_002381 1171373.PACID_07400 3.8e-212 743.8 Actinobacteria Bacteria 2GKQP@201174,COG0524@1,COG0524@2 NA|NA|NA G Carbohydrate kinase gnl|extdb|FAM19036-p1-1.1_002382 1171373.PACID_07390 4.5e-255 886.7 Propionibacteriales msmE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GP9H@201174,4DQ07@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_002384 1171373.PACID_07370 2.6e-133 481.5 Propionibacteriales ko:K10119 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GJNN@201174,4DPVF@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002385 1171373.PACID_07360 0.0 1538.5 Propionibacteriales clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2GJ73@201174,4DN44@85009,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE gnl|extdb|FAM19036-p1-1.1_002386 1171373.PACID_07350 1.3e-241 842.0 Bacteria ugpB ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria COG1653@1,COG1653@2 NA|NA|NA G carbohydrate transport gnl|extdb|FAM19036-p1-1.1_002387 1171373.PACID_07340 7.8e-163 579.7 Propionibacteriales ugpE ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 2GMTH@201174,4DU5W@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002388 1171373.PACID_07330 1e-157 562.8 Propionibacteriales ugpA ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GKJI@201174,4DQWD@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002389 1171373.PACID_07320 1.1e-130 472.6 Actinobacteria cof 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2HZD0@201174,COG0561@1,COG0561@2 NA|NA|NA T HAD hydrolase, family IIB gnl|extdb|FAM19036-p1-1.1_002390 1171373.PACID_07280 2.9e-154 551.2 Actinobacteria fda 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 Bacteria 2GN1A@201174,COG3588@1,COG3588@2 NA|NA|NA G Aldolase gnl|extdb|FAM19036-p1-1.1_002391 1171373.PACID_07270 2.7e-72 278.1 Bacteria dszD Bacteria COG1853@1,COG1853@2 NA|NA|NA S FMN binding gnl|extdb|FAM19036-p1-1.1_002396 1171373.PACID_07230 5e-114 417.2 Propionibacteriales Bacteria 2GJ46@201174,4DQC2@85009,COG2197@1,COG2197@2 NA|NA|NA T response regulator gnl|extdb|FAM19036-p1-1.1_002397 1171373.PACID_07220 9.5e-52 209.5 Bacteria Bacteria COG4767@1,COG4767@2 NA|NA|NA V VanZ like family gnl|extdb|FAM19036-p1-1.1_002398 1171373.PACID_07190 4.6e-111 407.5 Propionibacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4DNEX@85009,COG1136@1,COG1136@2 NA|NA|NA V COG1136 ABC-type antimicrobial peptide transport system, ATPase component gnl|extdb|FAM19036-p1-1.1_002399 1171373.PACID_07180 1.7e-223 782.7 Propionibacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJTZ@201174,4DQ29@85009,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain gnl|extdb|FAM19036-p1-1.1_002402 1171373.PACID_07150 8.5e-282 975.7 Actinobacteria ko:K03281,ko:K07085 ko00000 2.A.49,2.A.81 Bacteria 2GKDW@201174,COG0569@1,COG0569@2,COG2985@1,COG2985@2 NA|NA|NA P TrkA C-terminal domain protein gnl|extdb|FAM19036-p1-1.1_002403 1171373.PACID_07140 1.1e-135 489.2 Actinobacteria budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 2IBRH@201174,COG3527@1,COG3527@2 NA|NA|NA Q Belongs to the alpha-acetolactate decarboxylase family gnl|extdb|FAM19036-p1-1.1_002404 1171373.PACID_07130 7.3e-197 693.0 Actinobacteria Bacteria 2GNFX@201174,COG1063@1,COG1063@2 NA|NA|NA E Dehydrogenase gnl|extdb|FAM19036-p1-1.1_002405 1171373.PACID_07120 7.3e-74 283.1 Propionibacteriales hspR ko:K13640 ko00000,ko03000 Bacteria 2IQJ4@201174,4DVMZ@85009,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM19036-p1-1.1_002406 1171373.PACID_07110 1.1e-185 656.0 Propionibacteriales dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2GJKK@201174,4DNFB@85009,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins gnl|extdb|FAM19036-p1-1.1_002407 1171373.PACID_07100 2.8e-112 411.4 Actinobacteria grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K02652,ko:K03687 ko00000,ko02035,ko02044,ko03029,ko03110 3.A.15.2 Bacteria 2GP4F@201174,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ gnl|extdb|FAM19036-p1-1.1_002408 1171373.PACID_07090 0.0 1167.1 Propionibacteriales dnaK ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2GJTY@201174,4DP1V@85009,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein gnl|extdb|FAM19036-p1-1.1_002409 1171373.PACID_07080 3.7e-24 117.1 Actinobacteria Bacteria 2EITI@1,2GWHZ@201174,33CIU@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002410 1171373.PACID_07070 7.4e-174 616.7 Propionibacteriales pitA ko:K03306 ko00000 2.A.20 Bacteria 2GJHK@201174,4DND5@85009,COG0306@1,COG0306@2 NA|NA|NA P Phosphate transporter family gnl|extdb|FAM19036-p1-1.1_002411 1171373.PACID_07060 1.7e-128 465.3 Propionibacteriales Bacteria 2GIZB@201174,4DNE1@85009,COG0745@1,COG0745@2 NA|NA|NA T response regulator gnl|extdb|FAM19036-p1-1.1_002413 1171373.PACID_07040 2.5e-113 414.8 Propionibacteriales deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4,5.4.2.8 ko:K01619,ko:K01840 ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130 M00114 R01066,R01818 RC00408,RC00436,RC00437 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS00835 Bacteria 2GJIR@201174,4DNUJ@85009,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate gnl|extdb|FAM19036-p1-1.1_002414 1171373.PACID_07030 6.6e-144 516.5 Actinobacteria ko:K09992 ko00000 Bacteria 2IR9E@201174,COG3828@1,COG3828@2 NA|NA|NA S Trehalose utilisation gnl|extdb|FAM19036-p1-1.1_002415 1171373.PACID_07020 1.1e-201 709.5 Actinobacteria Bacteria 2GPZ0@201174,COG1716@1,COG1716@2 NA|NA|NA T (FHA) domain gnl|extdb|FAM19036-p1-1.1_002416 1171373.PACID_07000 0.0 1720.3 Propionibacteriales ppdK 2.7.3.13,2.7.9.1 ko:K01006,ko:K22424 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK73@201174,4DPDB@85009,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Belongs to the PEP-utilizing enzyme family gnl|extdb|FAM19036-p1-1.1_002417 1171373.PACID_06990 4.8e-165 587.0 Actinobacteria yqfL 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 2IDD1@201174,COG1806@1,COG1806@2 NA|NA|NA S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the gnl|extdb|FAM19036-p1-1.1_002419 1171373.PACID_06970 7.5e-155 553.1 Propionibacteriales serB 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 Bacteria 2GJDH@201174,4DN8I@85009,COG0560@1,COG0560@2 NA|NA|NA E phosphoserine phosphatase gnl|extdb|FAM19036-p1-1.1_002420 1171373.PACID_06960 3.3e-163 580.9 Actinobacteria yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.2.1.9,5.1.3.15 ko:K01687,ko:K01792 ko00010,ko00290,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00010,map00290,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R01209,R02739,R04441,R05070 RC00468,RC00563,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIUH@201174,COG0676@1,COG0676@2 NA|NA|NA G Belongs to the glucose-6-phosphate 1-epimerase family gnl|extdb|FAM19036-p1-1.1_002421 1171373.PACID_06950 3e-292 1010.4 Propionibacteriales cat1 GO:0003674,GO:0003824,GO:0003986,GO:0006082,GO:0006083,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008410,GO:0008775,GO:0009987,GO:0016289,GO:0016740,GO:0016782,GO:0016787,GO:0016788,GO:0016790,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043821,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0071704 2.8.3.18,3.1.2.1 ko:K01067,ko:K18118,ko:K22214 ko00020,ko00620,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00640,map00650,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00227,R10343,R11773 RC00004,RC00012,RC00014 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1125,iECIAI1_1343.ECIAI1_3040,iECSE_1348.ECSE_3182,iECW_1372.ECW_m3175,iEKO11_1354.EKO11_0812,iWFL_1372.ECW_m3175 Bacteria 2I9EB@201174,4DPYR@85009,COG0427@1,COG0427@2 NA|NA|NA C Acetyl-CoA hydrolase/transferase N-terminal domain gnl|extdb|FAM19036-p1-1.1_002422 1171373.PACID_06940 2.6e-121 441.4 Actinobacteria 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 2HFGX@201174,COG0546@1,COG0546@2 NA|NA|NA T hydrolase gnl|extdb|FAM19036-p1-1.1_002423 1171373.PACID_06880 1.2e-104 386.0 Propionibacteriales Bacteria 2GP92@201174,4DQYF@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002424 1171373.PACID_06870 4.9e-126 457.2 Propionibacteriales ybhF_2 ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I2I7@201174,4DQ62@85009,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter gnl|extdb|FAM19036-p1-1.1_002425 1171373.PACID_06860 1.7e-128 465.3 Propionibacteriales ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJ7Y@201174,4DN5F@85009,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein gnl|extdb|FAM19036-p1-1.1_002426 1410634.JHVD01000002_gene140 1.4e-06 60.1 Bacteria Bacteria 2DEXG@1,2ZPNB@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002427 1171373.PACID_06840 2.3e-139 501.5 Actinobacteria oppD3 ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2IBPT@201174,COG4608@1,COG4608@2 NA|NA|NA E ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_002428 1171373.PACID_06830 1.1e-267 928.7 Propionibacteriales amiB 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 2GKPZ@201174,4DP6D@85009,COG0154@1,COG0154@2 NA|NA|NA J Belongs to the amidase family gnl|extdb|FAM19036-p1-1.1_002430 1171373.PACID_06810 1.1e-80 305.8 Actinobacteria Bacteria 2IP1P@201174,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002434 1171373.PACID_06760 7.2e-136 490.0 Actinobacteria proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKMG@201174,COG0345@1,COG0345@2 NA|NA|NA E NADP oxidoreductase coenzyme F420-dependent gnl|extdb|FAM19036-p1-1.1_002435 1171373.PACID_06750 3.5e-191 674.1 Propionibacteriales adhA 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 2GNVQ@201174,4DP32@85009,COG1064@1,COG1064@2 NA|NA|NA S Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM19036-p1-1.1_002437 1171373.PACID_06730 0.0 1075.8 Propionibacteriales ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,4DN37@85009,COG1123@1,COG4172@2 NA|NA|NA O Belongs to the ABC transporter superfamily gnl|extdb|FAM19036-p1-1.1_002438 1171373.PACID_06720 6e-156 557.0 Propionibacteriales dppC ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GKAW@201174,4DT8T@85009,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002442 1416752.AYME01000017_gene1945 5.9e-158 563.9 Microbacteriaceae Bacteria 2GKIB@201174,4FMXD@85023,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM19036-p1-1.1_002443 1380347.JNII01000007_gene74 3.2e-84 318.5 Actinobacteria MA20_16875 iECBD_1354.ECBD_3826,iECB_1328.ECB_04075,iECS88_1305.ECS88_4797 Bacteria 2GJVP@201174,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase gnl|extdb|FAM19036-p1-1.1_002444 1171373.PACID_06690 2.6e-186 657.9 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJY9@201174,4DPWN@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_002445 1171373.PACID_06680 3.7e-178 630.9 Actinobacteria ko:K07058 ko00000 Bacteria 2GN79@201174,COG1295@1,COG1295@2 NA|NA|NA S Ribonuclease gnl|extdb|FAM19036-p1-1.1_002446 1171373.PACID_06670 6e-58 229.9 Actinobacteria ko:K07979 ko00000,ko03000 Bacteria 2IHTD@201174,COG1725@1,COG1725@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002447 1171373.PACID_06660 1.3e-169 602.4 Actinobacteria Bacteria 2F2DM@1,2HHW0@201174,33VBA@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002448 1171373.PACID_06650 3.1e-270 937.2 Propionibacteriales Bacteria 2GIUM@201174,4DPK1@85009,COG0477@1,COG0477@2 NA|NA|NA P major facilitator superfamily gnl|extdb|FAM19036-p1-1.1_002449 1171373.PACID_06640 9.6e-156 556.2 Propionibacteriales mdcF ko:K07088 ko00000 Bacteria 2GNIA@201174,4DPWX@85009,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein gnl|extdb|FAM19036-p1-1.1_002451 1171373.PACID_06620 1.1e-44 185.7 Actinobacteria Bacteria 2GVBU@201174,COG1308@1,COG1308@2 NA|NA|NA K Domain of unknown function (DUF4342) gnl|extdb|FAM19036-p1-1.1_002452 1171373.PACID_06610 2.1e-197 694.9 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GNVD@201174,4DQ2N@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_002453 1171373.PACID_06600 1.1e-46 192.6 Actinobacteria rhaU 5.1.3.32 ko:K03534 R10819 RC00563 ko00000,ko01000 Bacteria 2IQ69@201174,COG3254@1,COG3254@2 NA|NA|NA S L-rhamnose mutarotase gnl|extdb|FAM19036-p1-1.1_002454 1171373.PACID_06590 7.2e-253 879.4 Actinobacteria iolF ko:K06610 ko00000,ko02000 2.A.1.1.27 Bacteria 2I41G@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002455 1171373.PACID_06580 7.4e-230 802.7 Propionibacteriales rhaI 5.3.1.14 ko:K01820 ko00040,ko00051,ko01120,map00040,map00051,map01120 R01906,R02437,R06589 RC00376,RC00434,RC00516 ko00000,ko00001,ko01000 Bacteria 2GK1Z@201174,4DNEP@85009,COG4952@1,COG4952@2 NA|NA|NA M Isomerase gnl|extdb|FAM19036-p1-1.1_002456 1171373.PACID_06570 8.8e-292 1008.8 Propionibacteriales rhaB 2.7.1.17,2.7.1.5 ko:K00848,ko:K00854 ko00040,ko00051,ko01100,ko01120,map00040,map00051,map01100,map01120 M00014 R01639,R01902,R03014 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 2GISK@201174,4DNDU@85009,COG1070@1,COG1070@2 NA|NA|NA G FGGY family of carbohydrate kinases, N-terminal domain gnl|extdb|FAM19036-p1-1.1_002457 1171373.PACID_06560 4.2e-155 553.9 Actinobacteria rhaD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008994,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.17,4.1.2.19,5.1.3.4 ko:K01628,ko:K01629,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R01785,R02262,R02263,R05850 RC00438,RC00599,RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_5354,iECSP_1301.ECSP_4963,iECs_1301.ECs4829,iLF82_1304.LF82_1866,iNRG857_1313.NRG857_19475,iSFV_1184.SFV_3593,iSSON_1240.SSON_4072,iYL1228.KPN_04211,iZ_1308.Z5446,ic_1306.c4851 Bacteria 2IB1Y@201174,COG0235@1,COG0235@2 NA|NA|NA G Aldolase gnl|extdb|FAM19036-p1-1.1_002458 1171373.PACID_06550 1.2e-271 941.8 Actinobacteria aldA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004029,GO:0004777,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0008911,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019299,GO:0019301,GO:0019317,GO:0019318,GO:0019320,GO:0019752,GO:0022607,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042354,GO:0042355,GO:0042802,GO:0043436,GO:0043648,GO:0043649,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0048037,GO:0050569,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 iAF1260.b1415,iBWG_1329.BWG_1242,iECDH10B_1368.ECDH10B_1541,iECDH1ME8569_1439.ECDH1ME8569_1358,iEcDH1_1363.EcDH1_2230,iJO1366.b1415,iJR904.b1415,iY75_1357.Y75_RS07435 Bacteria 2GIWZ@201174,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_002459 1171373.PACID_06540 5.9e-32 142.9 Bacteria Bacteria 2DQPU@1,337ZH@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002460 1171373.PACID_06530 5.5e-102 377.1 Bacteria Bacteria COG4758@1,COG4758@2 NA|NA|NA KT membrane gnl|extdb|FAM19036-p1-1.1_002461 1171373.PACID_06520 2.1e-307 1060.8 Actinobacteria Bacteria 2H1X6@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002462 1171373.PACID_06510 2.6e-88 331.3 Actinobacteria ko:K09167 ko00000 Bacteria 2IR88@201174,COG3402@1,COG3402@2 NA|NA|NA S membrane gnl|extdb|FAM19036-p1-1.1_002463 1171373.PACID_06500 7.5e-259 899.4 Propionibacteriales ko:K08981 ko00000 Bacteria 2GJCD@201174,4DQ4J@85009,COG3428@1,COG3428@2 NA|NA|NA S overlaps another CDS with the same product name gnl|extdb|FAM19036-p1-1.1_002464 1171373.PACID_06490 1e-148 532.7 Propionibacteriales ppgK 2.7.1.2,2.7.1.63 ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786,R02187,R02189 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJA0@201174,4DQCW@85009,COG1940@1,COG1940@2 NA|NA|NA GK ROK family gnl|extdb|FAM19036-p1-1.1_002465 1171373.PACID_06470 0.0 1098.6 Propionibacteriales argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Bacteria 2GKQ3@201174,4DNTZ@85009,COG0018@1,COG0018@2 NA|NA|NA J Arginyl tRNA synthetase N terminal dom gnl|extdb|FAM19036-p1-1.1_002466 1171373.PACID_06460 1.6e-154 552.0 Propionibacteriales dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Bacteria 2GJQ7@201174,4DPFP@85009,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family gnl|extdb|FAM19036-p1-1.1_002467 1171373.PACID_06450 3.9e-251 873.6 Actinobacteria csbX Bacteria 2GPRH@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002468 1171373.PACID_15790 8.2e-235 819.3 Propionibacteriales Bacteria 2GM8F@201174,4DV2N@85009,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain gnl|extdb|FAM19036-p1-1.1_002469 1171373.PACID_06440 1.1e-173 615.9 Propionibacteriales proX ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iJN746.PP_2775 Bacteria 2GP39@201174,4DN5Y@85009,COG2113@1,COG2113@2 NA|NA|NA E Substrate binding domain of ABC-type glycine betaine transport system gnl|extdb|FAM19036-p1-1.1_002470 1171373.PACID_06430 2.4e-124 451.4 Actinobacteria sanA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 ko:K03748 ko00000 Bacteria 2GWVK@201174,COG2949@1,COG2949@2 NA|NA|NA S membrane gnl|extdb|FAM19036-p1-1.1_002471 1171373.PACID_06420 0.0 1128.2 Propionibacteriales pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJG0@201174,4DPRV@85009,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family gnl|extdb|FAM19036-p1-1.1_002472 1171373.PACID_06410 4.9e-114 417.2 Bacteria kdgA 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria COG0800@1,COG0800@2 NA|NA|NA G 2-dehydro-3-deoxy-phosphogluconate aldolase activity gnl|extdb|FAM19036-p1-1.1_002473 1171373.PACID_06400 0.0 1694.1 Propionibacteriales ko:K03727 ko00000,ko01000 Bacteria 2GJSV@201174,4DPKV@85009,COG4581@1,COG4581@2 NA|NA|NA L DEAD DEAH box helicase gnl|extdb|FAM19036-p1-1.1_002474 1171373.PACID_06390 1.5e-94 352.1 Actinobacteria Bacteria 2IKMG@201174,COG1514@1,COG1514@2 NA|NA|NA J 2'-5' RNA ligase superfamily gnl|extdb|FAM19036-p1-1.1_002475 1171373.PACID_06380 7.9e-87 326.2 Actinobacteria ko:K06910 ko00000 Bacteria 2GMIG@201174,COG1881@1,COG1881@2 NA|NA|NA S Phospholipid-binding protein gnl|extdb|FAM19036-p1-1.1_002477 1171373.PACID_06360 9.3e-119 433.0 Propionibacteriales Bacteria 2EKVV@1,2GYGM@201174,33EJD@2,4DW0T@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002479 1122998.AUHZ01000006_gene611 1e-140 506.1 Propionibacteriales 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 R01708 RC00116 ko00000,ko00001,ko01000 Bacteria 2GJ6R@201174,4DPYD@85009,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM19036-p1-1.1_002480 1171373.PACID_06320 3.4e-150 538.5 Bacteria ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria COG3942@1,COG3942@2 NA|NA|NA S pathogenesis gnl|extdb|FAM19036-p1-1.1_002481 1171373.PACID_06310 8.7e-57 226.1 Propionibacteriales crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2IKWG@201174,4DSKN@85009,COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity gnl|extdb|FAM19036-p1-1.1_002483 1171373.PACID_06290 1.3e-99 369.0 Actinobacteria 2.4.1.266 ko:K09118,ko:K13693 ko00000,ko01000,ko01003 GT81 Bacteria 2GUPR@201174,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family gnl|extdb|FAM19036-p1-1.1_002484 1171373.PACID_06280 7.2e-186 656.8 Propionibacteriales arsB ko:K03893 ko00000,ko02000 2.A.45.1,3.A.4.1 Bacteria 2GMQJ@201174,4DQUG@85009,COG1055@1,COG1055@2 NA|NA|NA P Arsenical pump membrane protein gnl|extdb|FAM19036-p1-1.1_002485 1171373.PACID_06270 1.5e-75 288.9 Actinobacteria uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2IFKZ@201174,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family gnl|extdb|FAM19036-p1-1.1_002486 1171373.PACID_06260 7.6e-163 579.7 Propionibacteriales yybE ko:K09681 ko00000,ko03000 Bacteria 2GTX3@201174,4DQK8@85009,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain gnl|extdb|FAM19036-p1-1.1_002489 1171373.PACID_06230 1.6e-291 1008.1 Propionibacteriales 3.5.1.104 ko:K22278 ko00000,ko01000 Bacteria 2HEQK@201174,4DSHQ@85009,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase gnl|extdb|FAM19036-p1-1.1_002490 1171373.PACID_06210 0.0 1196.4 Propionibacteriales murJ ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2GKN0@201174,4DNJI@85009,COG0728@1,COG0728@2 NA|NA|NA KLT MviN-like protein gnl|extdb|FAM19036-p1-1.1_002491 1171373.PACID_06200 1.8e-229 801.6 Propionibacteriales ask 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN0G@201174,4DN2D@85009,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family gnl|extdb|FAM19036-p1-1.1_002492 1171373.PACID_06190 2.5e-86 324.7 Propionibacteriales Bacteria 2I7RZ@201174,4DWIR@85009,COG4758@1,COG4758@2 NA|NA|NA S Domain of unknown function (DUF1707) gnl|extdb|FAM19036-p1-1.1_002493 1171373.PACID_06180 1.1e-192 679.1 Actinobacteria ddhD Bacteria 2GKW0@201174,COG0673@1,COG0673@2 NA|NA|NA C Oxidoreductase gnl|extdb|FAM19036-p1-1.1_002494 1171373.PACID_06170 3.6e-54 217.2 Bacteria ko:K06975 ko00000 Bacteria COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase gnl|extdb|FAM19036-p1-1.1_002496 1171373.PACID_06140 2.4e-142 511.5 Propionibacteriales Bacteria 2GP42@201174,4DR0A@85009,COG0561@1,COG0561@2 NA|NA|NA J hydrolases of the HAD superfamily gnl|extdb|FAM19036-p1-1.1_002497 1171373.PACID_06130 2.2e-145 521.5 Actinobacteria Bacteria 2GP42@201174,COG0561@1,COG0561@2 NA|NA|NA J hydrolase gnl|extdb|FAM19036-p1-1.1_002498 1122998.AUHZ01000023_gene1330 1.4e-202 712.6 Propionibacteriales thrE Bacteria 2GJMC@201174,4DPF6@85009,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE gnl|extdb|FAM19036-p1-1.1_002499 1171373.PACID_06100 8.8e-139 499.6 Propionibacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4DN6N@85009,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_002500 1171373.PACID_06090 1.8e-89 335.5 Propionibacteriales Bacteria 2GNA1@201174,4DQRK@85009,COG1695@1,COG1695@2 NA|NA|NA K Virulence activator alpha C-term gnl|extdb|FAM19036-p1-1.1_002501 1171373.PACID_06080 0.0 1273.8 Propionibacteriales bgaC 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GIUX@201174,4DTMR@85009,COG1874@1,COG1874@2 NA|NA|NA G Glycosyl hydrolases family 35 gnl|extdb|FAM19036-p1-1.1_002502 1171373.PACID_06070 2.4e-223 781.2 Propionibacteriales ybjJ_3 Bacteria 2I30D@201174,4DWGA@85009,COG2223@1,COG2223@2 NA|NA|NA P Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002503 1171373.PACID_06060 5.8e-49 199.9 Propionibacteriales GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2IQ7E@201174,4DR5J@85009,COG0011@1,COG0011@2 NA|NA|NA S Thiamine-binding protein gnl|extdb|FAM19036-p1-1.1_002504 1171373.PACID_06050 8.7e-113 412.9 Propionibacteriales recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJY0@201174,4DP0B@85009,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO gnl|extdb|FAM19036-p1-1.1_002505 1171373.PACID_06040 8.8e-32 142.9 Actinobacteria ybaB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K09747 ko00000 Bacteria 2IRC4@201174,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection gnl|extdb|FAM19036-p1-1.1_002509 1171373.PACID_06010 4.5e-61 240.4 Propionibacteriales hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.23,5.4.99.24 ko:K04762,ko:K06179,ko:K06180 ko00000,ko01000,ko03009,ko03110 Bacteria 2IQ6F@201174,4DV0F@85009,COG1188@1,COG1188@2 NA|NA|NA J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) gnl|extdb|FAM19036-p1-1.1_002511 1171373.PACID_05990 4.7e-134 483.8 Actinobacteria magIII ko:K07457 ko00000 Bacteria 2ICDU@201174,COG2231@1,COG2231@2 NA|NA|NA L Base excision DNA repair protein, HhH-GPD family gnl|extdb|FAM19036-p1-1.1_002513 1171373.PACID_05970 7.6e-286 989.2 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMSI@201174,4DNY7@85009,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide gnl|extdb|FAM19036-p1-1.1_002514 1171373.PACID_05960 3.4e-180 637.5 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKEH@201174,4DPD1@85009,COG1131@1,COG1131@2 NA|NA|NA V PFAM ABC transporter related gnl|extdb|FAM19036-p1-1.1_002515 1171373.PACID_05950 1.1e-120 439.5 Propionibacteriales Bacteria 2HD07@201174,4DSG2@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002517 1171373.PACID_05920 1.6e-179 635.2 Bacteria Bacteria COG2852@1,COG2852@2 NA|NA|NA L Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002519 1171373.PACID_05900 4.7e-108 397.1 Propionibacteriales padR ko:K10947 ko00000,ko03000 Bacteria 2IFDN@201174,4DR1C@85009,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family gnl|extdb|FAM19036-p1-1.1_002520 1171373.PACID_05890 1.2e-266 925.2 Actinobacteria ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily gnl|extdb|FAM19036-p1-1.1_002521 1171373.PACID_05880 0.0 1685.2 Propionibacteriales treY GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 ko:K00705,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000 GH13,GH77 Bacteria 2GJTB@201174,4DN4E@85009,COG3280@1,COG3280@2 NA|NA|NA G Alpha amylase, catalytic domain gnl|extdb|FAM19036-p1-1.1_002522 1122997.AUDD01000032_gene340 3.2e-103 381.7 Propionibacteriales Bacteria 2I47R@201174,4DX0K@85009,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002523 1121924.ATWH01000016_gene3018 3.3e-16 90.5 Microbacteriaceae Bacteria 2GS58@201174,4FSW2@85023,COG1724@1,COG1724@2 NA|NA|NA N mRNA binding gnl|extdb|FAM19036-p1-1.1_002524 1121924.ATWH01000016_gene3017 3.9e-13 81.3 Microbacteriaceae Bacteria 2GRYW@201174,4FQJV@85023,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 gnl|extdb|FAM19036-p1-1.1_002526 1171373.PACID_05860 4.4e-28 129.8 Bacteria Bacteria COG1724@1,COG1724@2 NA|NA|NA N mRNA binding gnl|extdb|FAM19036-p1-1.1_002527 1171373.PACID_05850 0.0 1127.5 Propionibacteriales treZ GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576 3.2.1.141 ko:K01236 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11256 RC00049 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2GMIS@201174,4DTC7@85009,COG0296@1,COG0296@2 NA|NA|NA G Alpha amylase, catalytic domain gnl|extdb|FAM19036-p1-1.1_002528 1171373.PACID_05840 2.7e-64 251.5 Bacteria Bacteria COG4767@1,COG4767@2 NA|NA|NA V VanZ like family gnl|extdb|FAM19036-p1-1.1_002529 1171373.PACID_05830 8.8e-177 626.3 Propionibacteriales Bacteria 2GJJJ@201174,4DQKI@85009,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain gnl|extdb|FAM19036-p1-1.1_002530 1122997.AUDD01000032_gene337 4.2e-34 151.8 Bacteria 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family gnl|extdb|FAM19036-p1-1.1_002531 1171373.PACID_05820 1.3e-202 712.2 Bacteria Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups gnl|extdb|FAM19036-p1-1.1_002532 1171373.PACID_03410 5e-198 696.8 Propionibacteriales Bacteria 2IAHV@201174,4DUEP@85009,COG3335@1,COG3335@2,COG3415@1,COG3415@2 NA|NA|NA L Winged helix-turn helix gnl|extdb|FAM19036-p1-1.1_002533 1171373.PACID_05810 8.1e-277 959.1 Propionibacteriales rfbP Bacteria 2GK0M@201174,4DPAD@85009,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase gnl|extdb|FAM19036-p1-1.1_002534 1171373.PACID_05800 3.4e-161 574.3 Propionibacteriales Bacteria 2HBSE@201174,4DTKA@85009,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase gnl|extdb|FAM19036-p1-1.1_002535 1171373.PACID_05790 0.0 1444.5 Propionibacteriales 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria 2H2QX@201174,4DT6V@85009,COG3408@1,COG3408@2 NA|NA|NA G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain gnl|extdb|FAM19036-p1-1.1_002536 1171373.PACID_05780 7.3e-120 437.2 Propionibacteriales ko:K03646 ko00000,ko02000 2.C.1.2 Bacteria 2GJ38@201174,4DQTH@85009,COG2356@1,COG2356@2,COG3064@1,COG3064@2 NA|NA|NA L Protein of unknown function (DUF1524) gnl|extdb|FAM19036-p1-1.1_002537 1171373.PACID_05770 7.5e-163 579.7 Propionibacteriales rfbA 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GP20@201174,4DNRQ@85009,COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis gnl|extdb|FAM19036-p1-1.1_002538 1171373.PACID_05760 1.3e-190 672.2 Propionibacteriales rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNDU@201174,4DPM2@85009,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily gnl|extdb|FAM19036-p1-1.1_002539 1171373.PACID_05750 3.5e-282 976.9 Propionibacteriales rmlC 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNY8@201174,4DN84@85009,COG1091@1,COG1091@2,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose gnl|extdb|FAM19036-p1-1.1_002540 1171373.PACID_05730 1.4e-127 462.2 Propionibacteriales fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GNU2@201174,4DQ6H@85009,COG1716@1,COG1716@2 NA|NA|NA T Protein of unknown function (DUF2662) gnl|extdb|FAM19036-p1-1.1_002541 1171373.PACID_05720 4.4e-83 313.9 Propionibacteriales fhaB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 Bacteria 2GKA7@201174,4DQIX@85009,COG1716@1,COG1716@2 NA|NA|NA T Inner membrane component of T3SS, cytoplasmic domain gnl|extdb|FAM19036-p1-1.1_002542 1171373.PACID_05710 1.7e-212 745.3 Propionibacteriales pstP 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 2GJ3M@201174,4DNAN@85009,COG0631@1,COG0631@2 NA|NA|NA T Serine/threonine phosphatases, family 2C, catalytic domain gnl|extdb|FAM19036-p1-1.1_002544 1171373.PACID_05690 2.8e-255 887.5 Propionibacteriales pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K05364 ko00550,map00550 R04519 RC00005,RC00049 ko00000,ko00001,ko01011 Bacteria 2GJUQ@201174,4DP0A@85009,COG0768@1,COG0768@2 NA|NA|NA M Penicillin binding protein transpeptidase domain gnl|extdb|FAM19036-p1-1.1_002545 1171373.PACID_05680 4e-251 874.0 Propionibacteriales 2.7.11.1,6.1.1.17 ko:K01885,ko:K12132 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01001,ko01007,ko02048,ko03016 Bacteria 2GJ1J@201174,4DNY6@85009,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM19036-p1-1.1_002546 1171373.PACID_05670 9.6e-123 446.0 Propionibacteriales trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01664,ko:K13950 ko00790,map00790 R01716 RC00010,RC01418 ko00000,ko00001,ko01000 Bacteria 2GJUX@201174,4DNQV@85009,COG0512@1,COG0512@2 NA|NA|NA EH Peptidase C26 gnl|extdb|FAM19036-p1-1.1_002551 1171373.PACID_05620 6.6e-120 436.8 Propionibacteriales hyuE 5.1.99.3 ko:K16841 ko00230,ko01120,map00230,map01120 R03925 RC01027 ko00000,ko00001,ko01000 Bacteria 2GKN4@201174,4DPHH@85009,COG4126@1,COG4126@2 NA|NA|NA E Asp/Glu/Hydantoin racemase gnl|extdb|FAM19036-p1-1.1_002552 1171373.PACID_05610 8.9e-292 1008.8 Propionibacteriales pucI ko:K03457 ko00000 2.A.39 iHN637.CLJU_RS07510 Bacteria 2GJXN@201174,4DPQ3@85009,COG1953@1,COG1953@2 NA|NA|NA FH Permease for cytosine/purines, uracil, thiamine, allantoin gnl|extdb|FAM19036-p1-1.1_002553 1171373.PACID_05600 1.3e-198 699.1 Propionibacteriales Bacteria 2I9I7@201174,4DTHK@85009,COG1301@1,COG1301@2 NA|NA|NA U Sodium:dicarboxylate symporter family gnl|extdb|FAM19036-p1-1.1_002554 1171373.PACID_05590 1.9e-258 897.9 Propionibacteriales allB 3.5.2.5 ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R02425 RC00680 ko00000,ko00001,ko00002,ko01000 Bacteria 2IAM1@201174,4DNU2@85009,COG0044@1,COG0044@2 NA|NA|NA F Amidohydrolase family gnl|extdb|FAM19036-p1-1.1_002556 1171373.PACID_05570 1.9e-250 871.3 Propionibacteriales amaB 3.5.1.6,3.5.1.87,3.5.3.9 ko:K02083,ko:K06016 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 M00046 R00905,R02423,R04666 RC00064,RC00096 ko00000,ko00001,ko00002,ko01000,ko01002 iPC815.YPO3249 Bacteria 2GJDE@201174,4DTB2@85009,COG0624@1,COG0624@2 NA|NA|NA E Peptidase family M28 gnl|extdb|FAM19036-p1-1.1_002557 1171373.PACID_05560 9e-153 546.2 Bacteria Bacteria COG1737@1,COG1737@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM19036-p1-1.1_002558 1171373.PACID_05550 8.3e-126 456.4 Propionibacteriales ko:K07090 ko00000 Bacteria 2GJCC@201174,4DNJB@85009,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE gnl|extdb|FAM19036-p1-1.1_002559 1171373.PACID_05540 5.7e-122 443.7 Actinobacteria Bacteria 2H1S8@201174,COG1802@1,COG1802@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002560 1171373.PACID_05530 7e-290 1002.7 Propionibacteriales sucD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009361,GO:0032991,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:1902494 6.2.1.5 ko:K01902,ko:K02381 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN20@201174,4DTVP@85009,COG0074@1,COG0074@2 NA|NA|NA C CoA-ligase gnl|extdb|FAM19036-p1-1.1_002561 1171373.PACID_05520 4.8e-246 856.7 Propionibacteriales sucD 6.2.1.5 ko:K01902,ko:K02381 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMFI@201174,4DPG6@85009,COG0074@1,COG0074@2 NA|NA|NA C Protein of unknown function (DUF1116) gnl|extdb|FAM19036-p1-1.1_002562 1171373.PACID_05510 8.1e-149 533.1 Bacteria Bacteria 2DC1F@1,2ZCE5@2 NA|NA|NA S Protein of unknown function (DUF2877) gnl|extdb|FAM19036-p1-1.1_002563 1171373.PACID_05500 3.4e-180 637.5 Propionibacteriales arcC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_0454,iECED1_1282.ECED1_0540,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iJN746.PP_0999 Bacteria 2HWQ6@201174,4DQBT@85009,COG0549@1,COG0549@2 NA|NA|NA E Amino acid kinase family gnl|extdb|FAM19036-p1-1.1_002564 1171373.PACID_05490 3.3e-83 314.3 Actinobacteria Bacteria 2IQZD@201174,COG0716@1,COG0716@2 NA|NA|NA C FMN binding gnl|extdb|FAM19036-p1-1.1_002565 1171373.PACID_05480 3.4e-150 537.7 Actinobacteria Bacteria 2IKBM@201174,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002566 1171373.PACID_05470 4.7e-117 427.2 Actinobacteria Z012_10800 3.1.3.23 ko:K19270 ko00000,ko01000 Bacteria 2GNX0@201174,COG0637@1,COG0637@2 NA|NA|NA V TIGRFAM HAD-superfamily hydrolase subfamily IA, variant 3 gnl|extdb|FAM19036-p1-1.1_002567 1171373.PACID_05460 7.8e-96 356.7 Propionibacteriales Bacteria 2IQGF@201174,4DRWJ@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002568 1171373.PACID_05450 1.9e-298 1031.2 Propionibacteriales ycfI GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4DNXB@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM19036-p1-1.1_002570 1171373.PACID_05430 3.7e-193 680.6 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4DNIR@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_002571 1171373.PACID_05410 3.1e-159 567.8 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GMTW@201174,4DNHP@85009,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002572 1171373.PACID_05400 8.2e-157 559.7 Propionibacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJPZ@201174,4DNSJ@85009,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002573 1171373.PACID_05390 5.3e-232 810.1 Propionibacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4DPIZ@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_002574 1171373.PACID_05380 4e-304 1050.0 Propionibacteriales bgaC 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GIUX@201174,4DPWP@85009,COG1874@1,COG1874@2 NA|NA|NA G Glycosyl hydrolases family 35 gnl|extdb|FAM19036-p1-1.1_002575 1171373.PACID_05370 5.2e-196 690.3 Propionibacteriales eutG 1.1.1.1,4.3.3.7 ko:K00001,ko:K01714 ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230 M00016,M00525,M00526,M00527 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2IDI8@201174,4DWNA@85009,COG1454@1,COG1454@2 NA|NA|NA C Iron-containing alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_002576 1171373.PACID_05360 1.7e-106 393.3 Actinobacteria ko:K08177,ko:K19577 ko00000,ko02000 2.A.1.11,2.A.1.2.65 Bacteria 2GIZX@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002579 1171373.PACID_05330 1.7e-79 302.0 Propionibacteriales Bacteria 2IP6R@201174,4DRE2@85009,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain gnl|extdb|FAM19036-p1-1.1_002580 1171373.PACID_05310 3.5e-230 804.3 Actinobacteria Bacteria 2GPIM@201174,COG0457@1,COG0457@2,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_002581 1171373.PACID_05300 5.1e-72 276.9 Bacteria blaI GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 Bacteria COG3682@1,COG3682@2 NA|NA|NA K negative regulation of transcription, DNA-templated gnl|extdb|FAM19036-p1-1.1_002582 1171373.PACID_05290 8.5e-271 939.1 Propionibacteriales cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 2GJE4@201174,4DNI9@85009,COG1271@1,COG1271@2 NA|NA|NA C Cytochrome bd terminal oxidase subunit I gnl|extdb|FAM19036-p1-1.1_002583 1171373.PACID_05280 9.2e-203 712.6 Propionibacteriales cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120 Bacteria 2GMFV@201174,4DN35@85009,COG1294@1,COG1294@2 NA|NA|NA C oxidase, subunit gnl|extdb|FAM19036-p1-1.1_002585 1171373.PACID_05260 6.9e-246 856.7 Propionibacteriales cydC ko:K06148,ko:K16012,ko:K16014 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1,3.A.1.129 Bacteria 2H79B@201174,4DWZE@85009,COG4987@1,COG4987@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM19036-p1-1.1_002586 1122997.AUDD01000028_gene692 2.9e-25 122.5 Propionibacteriales Bacteria 2I47R@201174,4DX0K@85009,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002587 1171373.PACID_05250 5.7e-118 430.3 Propionibacteriales ko:K00782,ko:K18929 ko00000 Bacteria 2GNUJ@201174,4DRME@85009,COG1556@1,COG1556@2 NA|NA|NA S LUD domain gnl|extdb|FAM19036-p1-1.1_002588 1171373.PACID_05240 3.5e-288 996.9 Propionibacteriales lutB ko:K18929 ko00000 Bacteria 2GJDR@201174,4DQ12@85009,COG0247@1,COG0247@2,COG1139@1,COG1139@2 NA|NA|NA C LUD domain gnl|extdb|FAM19036-p1-1.1_002589 1171373.PACID_05230 1.1e-152 545.8 Propionibacteriales lutA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K18928 ko00000 iEC042_1314.EC042_0340,iEcSMS35_1347.EcSMS35_0338 Bacteria 2GIVX@201174,4DNWX@85009,COG0247@1,COG0247@2 NA|NA|NA C Cysteine-rich domain gnl|extdb|FAM19036-p1-1.1_002590 1171373.PACID_05220 3.5e-289 1000.3 Propionibacteriales ko:K03303 ko00000,ko02000 2.A.14 Bacteria 2GIUF@201174,4DPUA@85009,COG1620@1,COG1620@2 NA|NA|NA C L-lactate permease gnl|extdb|FAM19036-p1-1.1_002593 1171373.PACID_05180 0.0 1154.0 Propionibacteriales preT 1.2.7.1 ko:K00171,ko:K03737 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0A@201174,4DU0U@85009,COG0493@1,COG0493@2,COG1144@1,COG1144@2 NA|NA|NA C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gnl|extdb|FAM19036-p1-1.1_002594 1171373.PACID_05170 0.0 2399.4 Propionibacteriales nifJ GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 iJN678.nifJ Bacteria 2I995@201174,4DVUV@85009,COG0674@1,COG0674@2,COG1013@1,COG1013@2,COG1014@1,COG1014@2,COG1145@1,COG1145@2 NA|NA|NA C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin gnl|extdb|FAM19036-p1-1.1_002595 1171373.PACID_05160 5.8e-183 646.7 Actinobacteria 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN1V@201174,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate gnl|extdb|FAM19036-p1-1.1_002597 188626.HMPREF0321_2006 9.2e-102 377.1 Dermacoccaceae wbiB 5.1.3.25 ko:K17947 ko00523,ko01130,map00523,map01130 R10279 RC00289 ko00000,ko00001,ko01000 Bacteria 1ZX0V@145357,2GK8K@201174,COG0451@1,COG0451@2 NA|NA|NA M Male sterility protein gnl|extdb|FAM19036-p1-1.1_002598 1170318.PALO_09580 2e-94 352.1 Propionibacteriales neuA 2.7.7.43,2.7.7.92 ko:K00983,ko:K21749 ko00520,ko01100,map00520,map01100 R01117,R04215 RC00152 ko00000,ko00001,ko01000 Bacteria 2I2ET@201174,4DTYP@85009,COG1083@1,COG1083@2 NA|NA|NA M Cytidylyltransferase gnl|extdb|FAM19036-p1-1.1_002599 1170318.PALO_09585 0.0 1293.5 Propionibacteriales 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 R01804,R04435 RC00159 ko00000,ko00001,ko01000 Bacteria 2GJC9@201174,4DN85@85009,COG0517@1,COG0517@2,COG1082@1,COG1082@2,COG2089@1,COG2089@2 NA|NA|NA M NeuB family gnl|extdb|FAM19036-p1-1.1_002600 35754.JNYJ01000036_gene3730 2.9e-26 127.1 Micromonosporales Bacteria 2IACA@201174,4DBUF@85008,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family gnl|extdb|FAM19036-p1-1.1_002601 188626.HMPREF0321_2019 9.6e-168 597.8 Dermacoccaceae Bacteria 1ZX1E@145357,2GPV4@201174,COG0438@1,COG0438@2,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase family 21 gnl|extdb|FAM19036-p1-1.1_002603 1170318.PALO_09605 2.5e-100 372.1 Actinobacteria Bacteria 2GP1N@201174,COG1216@1,COG1216@2 NA|NA|NA S PFAM Glycosyl transferase family 2 gnl|extdb|FAM19036-p1-1.1_002604 1170318.PALO_09610 8.7e-132 477.6 Actinobacteria ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2HXAQ@201174,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter ATP-binding gnl|extdb|FAM19036-p1-1.1_002605 446465.Bfae_26470 8.2e-37 161.0 Actinobacteria ko:K13665 ko00000 Bacteria 2IAU0@201174,COG2327@1,COG2327@2 NA|NA|NA S Polysaccharide pyruvyl transferase gnl|extdb|FAM19036-p1-1.1_002606 1479623.JHEL01000015_gene1344 2.4e-69 269.6 Actinobacteria Bacteria 2GJBP@201174,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 gnl|extdb|FAM19036-p1-1.1_002607 272559.BF9343_0185 1.2e-16 94.4 Bacteroidaceae 2.4.1.166 ko:K00745 ko00000,ko01000 GT2 Bacteria 2G06Z@200643,4AV2G@815,4NQ67@976,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 gnl|extdb|FAM19036-p1-1.1_002608 1274.HX89_10665 4.7e-48 199.5 Dermacoccaceae Bacteria 1ZX1E@145357,2GPV4@201174,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase family 21 gnl|extdb|FAM19036-p1-1.1_002609 1170318.PALO_09625 5.1e-102 377.9 Actinobacteria Bacteria 28P02@1,2IGAI@201174,2ZBWS@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002610 1461579.CCNK01000031_gene1115 6.5e-18 98.2 Pasteurellales ko:K07270 ko00000 GT25 Bacteria 1N6UQ@1224,1SYJ4@1236,1YAWH@135625,COG3306@1,COG3306@2 NA|NA|NA M Glycosyltransferase family 25 (LPS biosynthesis protein) gnl|extdb|FAM19036-p1-1.1_002611 1170318.PALO_09630 2.2e-110 405.6 Actinobacteria ko:K06320,ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 2ID8X@201174,COG4641@1,COG4641@2 NA|NA|NA S Glycosyl transferases group 1 gnl|extdb|FAM19036-p1-1.1_002613 1170318.PALO_09620 1.3e-98 366.7 Actinobacteria Bacteria 2IJ4J@201174,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 gnl|extdb|FAM19036-p1-1.1_002614 1170318.PALO_09635 1.8e-82 313.2 Actinobacteria Bacteria 2EZET@1,2II9H@201174,33SJY@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002615 1170318.PALO_09640 2.1e-150 539.3 Propionibacteriales 2.7.10.2 ko:K08253,ko:K16692 ko00000,ko01000,ko01001 Bacteria 2GJ1Y@201174,4DMYV@85009,COG0489@1,COG0489@2,COG3944@1,COG3944@2 NA|NA|NA DM AAA domain gnl|extdb|FAM19036-p1-1.1_002616 1170318.PALO_09680 2.1e-96 359.0 Actinobacteria Bacteria 2BGRN@1,2IIE3@201174,32AQR@2 NA|NA|NA Q Uncharacterised nucleotidyltransferase gnl|extdb|FAM19036-p1-1.1_002618 1121933.AUHH01000009_gene763 1.7e-24 119.4 Propionibacteriales cysC 2.7.7.4,3.1.3.48 ko:K00958,ko:K01104 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMPR@201174,4DSKW@85009,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family gnl|extdb|FAM19036-p1-1.1_002619 1171373.PACID_05830 4.5e-128 464.5 Propionibacteriales Bacteria 2GJJJ@201174,4DQKI@85009,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain gnl|extdb|FAM19036-p1-1.1_002620 710696.Intca_1195 2e-47 196.4 Intrasporangiaceae ko:K03671,ko:K16089 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko02000,ko03110 1.B.14.1,1.B.14.10 Bacteria 2IMCX@201174,4FH2W@85021,COG0526@1,COG0526@2 NA|NA|NA CO Methylamine utilisation protein MauE gnl|extdb|FAM19036-p1-1.1_002622 1035308.AQYY01000001_gene1502 3.1e-49 202.2 Bacteria ko:K06915 ko00000 Bacteria COG0433@1,COG0433@2 NA|NA|NA S helicase activity gnl|extdb|FAM19036-p1-1.1_002623 1193181.BN10_720023 5.7e-10 70.1 Intrasporangiaceae Bacteria 29ZI9@1,2H0G9@201174,30MIC@2,4FI0K@85021 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002624 1171373.PACID_05140 1.6e-165 589.0 Propionibacteriales rlpA ko:K03642,ko:K21688 ko00000 Bacteria 2IRQI@201174,4DWKR@85009,COG0797@1,COG0797@2,COG3583@1,COG3583@2 NA|NA|NA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides gnl|extdb|FAM19036-p1-1.1_002625 1171373.PACID_05130 0.0 1331.2 Propionibacteriales 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2GIRF@201174,4DN8M@85009,COG2217@1,COG2217@2 NA|NA|NA P Heavy-metal-associated domain gnl|extdb|FAM19036-p1-1.1_002626 1171373.PACID_05120 2.1e-41 175.6 Propionibacteriales Bacteria 2GQK5@201174,4DS67@85009,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain gnl|extdb|FAM19036-p1-1.1_002627 1171373.PACID_05110 2.5e-56 224.6 Propionibacteriales csoR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K21600 ko00000,ko03000 Bacteria 2IQAC@201174,4DRND@85009,COG1937@1,COG1937@2 NA|NA|NA S Metal-sensitive transcriptional repressor gnl|extdb|FAM19036-p1-1.1_002628 1171373.PACID_05100 1.2e-247 862.1 Propionibacteriales dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 2GKXQ@201174,4DN0Y@85009,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication gnl|extdb|FAM19036-p1-1.1_002629 1171373.PACID_05090 0.0 1137.5 Propionibacteriales nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 2GKIK@201174,4DNTA@85009,COG3004@1,COG3004@2 NA|NA|NA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons gnl|extdb|FAM19036-p1-1.1_002630 1123065.ATWL01000009_gene1068 3.1e-110 405.6 Actinobacteria Bacteria 2GKQB@201174,COG3385@1,COG3385@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_002631 1171373.PACID_05080 1.1e-52 212.2 Propionibacteriales trxA 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 2IQ9T@201174,4DRDT@85009,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family gnl|extdb|FAM19036-p1-1.1_002632 1171373.PACID_05070 9e-184 649.4 Propionibacteriales trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K22345 ko00030,ko00450,map00030,map00450 R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000 iPC815.YPO1374 Bacteria 2GKD2@201174,4DPPP@85009,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family gnl|extdb|FAM19036-p1-1.1_002633 1171373.PACID_05060 6.8e-95 353.2 Propionibacteriales btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 2IFJH@201174,4DQMK@85009,COG0386@1,COG0386@2 NA|NA|NA O Glutathione peroxidase gnl|extdb|FAM19036-p1-1.1_002634 1171373.PACID_05050 3.3e-86 324.3 Bacteria mgrA GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K18906 M00700,M00702,M00704,M00717 ko00000,ko00002,ko01504,ko03000 Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM19036-p1-1.1_002636 1171373.PACID_05030 2.8e-51 207.6 Actinobacteria Bacteria 2EDIK@1,2GQPY@201174,337EH@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002637 1171373.PACID_05020 9.7e-59 233.0 Propionibacteriales ligT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 ko:K01975 ko00000,ko01000,ko03016 Bacteria 2GNDN@201174,4DQZQ@85009,COG1514@1,COG1514@2 NA|NA|NA J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester gnl|extdb|FAM19036-p1-1.1_002638 1171373.PACID_05010 2.4e-107 394.8 Propionibacteriales mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNW1@201174,4DQWP@85009,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family gnl|extdb|FAM19036-p1-1.1_002639 1171373.PACID_05000 1.3e-93 349.0 Actinobacteria Bacteria 2DQ2A@1,2I1WX@201174,334FV@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002640 1171373.PACID_04990 3e-223 780.8 Propionibacteriales bplE Bacteria 2IDAG@201174,4DTCI@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM19036-p1-1.1_002641 1171373.PACID_04980 0.0 1545.4 Propionibacteriales hrpB 3.6.4.13 ko:K03579 ko00000,ko01000 Bacteria 2GMAW@201174,4DPC5@85009,COG1643@1,COG1643@2 NA|NA|NA L ATP-dependent helicase HrpB gnl|extdb|FAM19036-p1-1.1_002642 1171373.PACID_04970 2.4e-115 421.4 Bacteria mutT 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria COG0494@1,COG0494@2 NA|NA|NA L nUDIX hydrolase gnl|extdb|FAM19036-p1-1.1_002644 1122997.AUDD01000021_gene2182 3.6e-106 391.3 Propionibacteriales sseA 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 Bacteria 2GMDR@201174,4DQ8V@85009,COG2897@1,COG2897@2 NA|NA|NA P Rhodanese Homology Domain gnl|extdb|FAM19036-p1-1.1_002647 1123024.AUII01000001_gene3035 2.7e-13 82.0 Bacteria Bacteria 2FGEP@1,348AQ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002648 1146883.BLASA_0049 1.9e-35 156.0 Actinobacteria 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 2IC2H@201174,COG3550@1,COG3550@2 NA|NA|NA S peptidyl-serine autophosphorylation gnl|extdb|FAM19036-p1-1.1_002649 1171373.PACID_04920 9.3e-147 526.2 Actinobacteria Bacteria 2DBHY@1,2GM2H@201174,2Z9DM@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002650 1171373.PACID_04910 4.6e-147 527.7 Propionibacteriales Bacteria 2GJQF@201174,4DRKP@85009,COG5542@1,COG5542@2 NA|NA|NA S integral membrane protein gnl|extdb|FAM19036-p1-1.1_002651 1292373.H640_00275 3.8e-62 246.1 Bacteria Bacteria 2DUM4@1,33R7M@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002653 1171373.PACID_04880 1.3e-204 718.8 Propionibacteriales wecB 5.1.3.14,5.1.3.23 ko:K01791,ko:K13019 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420,R09600 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2GJWS@201174,4DNA6@85009,COG0381@1,COG0381@2 NA|NA|NA M UDP-N-acetylglucosamine 2-epimerase gnl|extdb|FAM19036-p1-1.1_002654 1171373.PACID_04870 1.4e-214 751.9 Propionibacteriales wblG Bacteria 2GNUU@201174,4DTBU@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 gnl|extdb|FAM19036-p1-1.1_002656 1171373.PACID_04850 1.9e-255 887.9 Propionibacteriales wecC 1.1.1.336 ko:K02472,ko:K02474 ko00520,ko05111,map00520,map05111 R03317,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 Bacteria 2GK5K@201174,4DPZW@85009,COG0677@1,COG0677@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family gnl|extdb|FAM19036-p1-1.1_002657 1171373.PACID_04830 4.3e-133 480.7 Propionibacteriales gluA 3.6.3.21 ko:K02028,ko:K10008 ko02010,map02010 M00233,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GIZW@201174,4DNTI@85009,COG1126@1,COG1126@2 NA|NA|NA E ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_002658 1171373.PACID_04820 7.6e-144 516.5 Propionibacteriales gluB ko:K10005 ko02010,map02010 M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 Bacteria 2GJH8@201174,4DPUC@85009,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins gnl|extdb|FAM19036-p1-1.1_002659 1171373.PACID_04810 1.9e-116 425.2 Propionibacteriales gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GNUR@201174,4DR1N@85009,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002660 1171373.PACID_04800 1e-157 562.8 Propionibacteriales gluD ko:K02029,ko:K10007 ko02010,map02010 M00233,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GNBH@201174,4DQVW@85009,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002661 1171373.PACID_04790 4.2e-133 480.7 Propionibacteriales fruR ko:K02081,ko:K03436 ko00000,ko03000 Bacteria 2GKWM@201174,4DQMJ@85009,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain gnl|extdb|FAM19036-p1-1.1_002662 1171373.PACID_04780 1.4e-173 615.5 Propionibacteriales fruK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0008662,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0019320,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iAF1260.b2168,iAPECO1_1312.APECO1_4386,iB21_1397.B21_02056,iEC042_1314.EC042_2401,iEC55989_1330.EC55989_2421,iECABU_c1320.ECABU_c24990,iECBD_1354.ECBD_1490,iECB_1328.ECB_02097,iECDH10B_1368.ECDH10B_2325,iECDH1ME8569_1439.ECDH1ME8569_2104,iECD_1391.ECD_02097,iECED1_1282.ECED1_2616,iECH74115_1262.ECH74115_3304,iECIAI1_1343.ECIAI1_2248,iECIAI39_1322.ECIAI39_2308,iECNA114_1301.ECNA114_2259,iECO103_1326.ECO103_2643,iECO111_1330.ECO111_2886,iECO26_1355.ECO26_3080,iECOK1_1307.ECOK1_2400,iECP_1309.ECP_2208,iECS88_1305.ECS88_2316,iECSE_1348.ECSE_2436,iECSF_1327.ECSF_2049,iECSP_1301.ECSP_3046,iECUMN_1333.ECUMN_2504,iECW_1372.ECW_m2369,iECs_1301.ECs3060,iEKO11_1354.EKO11_1586,iETEC_1333.ETEC_2303,iEcDH1_1363.EcDH1_1490,iEcHS_1320.EcHS_A2305,iEcSMS35_1347.EcSMS35_2315,iEcolC_1368.EcolC_1480,iG2583_1286.G2583_2711,iJO1366.b2168,iJR904.b2168,iLF82_1304.LF82_0744,iNRG857_1313.NRG857_11005,iPC815.YPO1299,iSBO_1134.SBO_2156,iSDY_1059.SDY_2316,iSFV_1184.SFV_2243,iSF_1195.SF2253,iSFxv_1172.SFxv_2486,iS_1188.S2382,iUMN146_1321.UM146_05955,iUMNK88_1353.UMNK88_2713,iUTI89_1310.UTI89_C2443,iWFL_1372.ECW_m2369,iY75_1357.Y75_RS11345,iZ_1308.Z3426,ic_1306.c2703 Bacteria 2GK7E@201174,4DQ47@85009,COG1105@1,COG1105@2 NA|NA|NA G Belongs to the carbohydrate kinase PfkB family gnl|extdb|FAM19036-p1-1.1_002663 1171373.PACID_04770 0.0 1168.7 Propionibacteriales fruA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090582 2.7.1.200,2.7.1.202,2.7.1.56 ko:K00882,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K03491,ko:K11202 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279,M00306 R02071,R03232,R05570 RC00002,RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1 iEcSMS35_1347.EcSMS35_2314,iJN746.PP_0795,iSbBS512_1146.SbBS512_E0796 Bacteria 2GJU4@201174,4DPEC@85009,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2 NA|NA|NA G phosphotransferase system gnl|extdb|FAM19036-p1-1.1_002664 1171373.PACID_04760 6e-36 156.4 Propionibacteriales ptsH ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 2GQX6@201174,4DSGS@85009,COG1925@1,COG1925@2 NA|NA|NA G PTS HPr component phosphorylation site gnl|extdb|FAM19036-p1-1.1_002665 1171373.PACID_04750 3.3e-180 637.5 Actinobacteria Bacteria 2II40@201174,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score gnl|extdb|FAM19036-p1-1.1_002666 1171373.PACID_04740 1.3e-207 729.2 Bacteria Bacteria 2DRPT@1,33CHW@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002667 1171373.PACID_04730 1e-184 652.5 Propionibacteriales MA20_07975 Bacteria 2GJCY@201174,4DPWQ@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold gnl|extdb|FAM19036-p1-1.1_002668 1171373.PACID_04720 6.4e-207 726.5 Propionibacteriales stsC Bacteria 2GKD7@201174,4DPCW@85009,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family gnl|extdb|FAM19036-p1-1.1_002669 1171373.PACID_04710 3.6e-79 301.2 Propionibacteriales wbpD Bacteria 2H5M0@201174,4DQG8@85009,COG0110@1,COG0110@2 NA|NA|NA S Hexapeptide repeat of succinyl-transferase gnl|extdb|FAM19036-p1-1.1_002670 1171373.PACID_04700 7.7e-258 896.0 Actinobacteria ko:K16705 ko00000 Bacteria 2IDMZ@201174,COG3307@1,COG3307@2 NA|NA|NA M O-Antigen ligase gnl|extdb|FAM19036-p1-1.1_002671 1171373.PACID_04690 1e-240 839.0 Actinobacteria Bacteria 2IT2P@201174,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 gnl|extdb|FAM19036-p1-1.1_002672 1171373.PACID_04680 8.3e-211 739.6 Actinobacteria 2.7.10.1,2.7.10.2 ko:K08252,ko:K08253,ko:K16692 ko00000,ko01000,ko01001 Bacteria 2GJ1Y@201174,COG0489@1,COG0489@2,COG3944@1,COG3944@2 NA|NA|NA DM biosynthesis protein gnl|extdb|FAM19036-p1-1.1_002673 1122997.AUDD01000021_gene2194 1.3e-20 107.8 Bacteria Bacteria 2DRPT@1,33CHW@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002675 1171373.PACID_04670 1.7e-238 831.6 Bacteria Bacteria COG3307@1,COG3307@2 NA|NA|NA M -O-antigen gnl|extdb|FAM19036-p1-1.1_002676 1171373.PACID_04660 1.1e-214 752.3 Actinobacteria Bacteria 2IFI5@201174,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 gnl|extdb|FAM19036-p1-1.1_002677 1171373.PACID_04650 7.4e-244 849.4 Actinobacteria Bacteria 2IT2P@201174,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 gnl|extdb|FAM19036-p1-1.1_002678 1171373.PACID_04640 1.1e-228 798.9 Actinobacteria Bacteria 2IT2P@201174,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 gnl|extdb|FAM19036-p1-1.1_002679 1171373.PACID_04630 8.6e-75 286.2 Actinobacteria wxcN Bacteria 2IIGF@201174,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein gnl|extdb|FAM19036-p1-1.1_002680 1171373.PACID_04620 1.5e-234 818.5 Actinobacteria Bacteria 2IG12@201174,COG5542@1,COG5542@2 NA|NA|NA S integral membrane protein gnl|extdb|FAM19036-p1-1.1_002681 1171373.PACID_04610 1.1e-176 625.9 Propionibacteriales ykcC 2.4.1.83 ko:K00721,ko:K20534 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 2I3C0@201174,4DT3N@85009,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 gnl|extdb|FAM19036-p1-1.1_002682 1292373.H640_02627 1.5e-24 120.9 Bacteria Bacteria 2DRPT@1,33CHW@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002686 1122998.AUHZ01000010_gene1474 6.3e-67 260.0 Actinobacteria Bacteria 2CQNK@1,2IIJ7@201174,32SMG@2 NA|NA|NA S Family of unknown function (DUF5318) gnl|extdb|FAM19036-p1-1.1_002688 1171373.PACID_04540 5e-240 836.6 Actinobacteria ko:K07263 ko00000,ko01000,ko01002 Bacteria 2GJZ3@201174,COG0612@1,COG0612@2 NA|NA|NA S Belongs to the peptidase M16 family gnl|extdb|FAM19036-p1-1.1_002691 1171373.PACID_04510 6.5e-19 99.8 Actinobacteria Bacteria 2IR4U@201174,COG4334@1,COG4334@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2255) gnl|extdb|FAM19036-p1-1.1_002692 1171373.PACID_04500 6.9e-74 283.5 Actinobacteria Bacteria 2DM8J@1,2I7RY@201174,32695@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002693 1171373.PACID_04490 1.4e-68 265.4 Propionibacteriales arsC 1.20.4.1 ko:K03325,ko:K03741 ko00000,ko01000,ko02000 2.A.59 Bacteria 2IHR3@201174,4DQUH@85009,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family gnl|extdb|FAM19036-p1-1.1_002694 1171373.PACID_04470 5.5e-153 547.0 Actinobacteria Bacteria 2GKUU@201174,COG3173@1,COG3173@2 NA|NA|NA K Aminoglycoside phosphotransferase gnl|extdb|FAM19036-p1-1.1_002695 1380356.JNIK01000013_gene3893 2.6e-84 318.5 Frankiales 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 2H3SA@201174,4EUA6@85013,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase gnl|extdb|FAM19036-p1-1.1_002696 1171373.PACID_04460 1.3e-70 272.7 Bacteria Bacteria 2996G@1,2ZW9T@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002697 1171373.PACID_04450 3.6e-119 434.5 Actinobacteria Bacteria 2GJUE@201174,COG2267@1,COG2267@2 NA|NA|NA I Alpha beta hydrolase gnl|extdb|FAM19036-p1-1.1_002698 1171373.PACID_04440 4.1e-209 733.8 Propionibacteriales Bacteria 2GK95@201174,4DMYB@85009,COG2072@1,COG2072@2 NA|NA|NA P Flavin-binding monooxygenase-like gnl|extdb|FAM19036-p1-1.1_002699 1171373.PACID_04430 1.2e-39 168.7 Bacteria Bacteria COG1403@1,COG1403@2 NA|NA|NA V endonuclease activity gnl|extdb|FAM19036-p1-1.1_002701 1171373.PACID_04400 6e-67 260.0 Propionibacteriales Bacteria 2IQB4@201174,4DRSQ@85009,COG0346@1,COG0346@2 NA|NA|NA E glyoxalase bleomycin resistance protein dioxygenase gnl|extdb|FAM19036-p1-1.1_002702 1171373.PACID_04390 9e-95 352.8 Propionibacteriales yncA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 2IHSY@201174,4DR6D@85009,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_002703 1171373.PACID_04380 1.8e-119 435.3 Propionibacteriales moaC 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 iAF987.Gmet_0302 Bacteria 2GMCN@201174,4DQQW@85009,COG2258@1,COG2258@2 NA|NA|NA S MOSC domain gnl|extdb|FAM19036-p1-1.1_002705 1171373.PACID_04360 5.2e-187 660.2 Propionibacteriales ko:K03699 ko00000,ko02042 Bacteria 2GJ8X@201174,4DNDS@85009,COG1253@1,COG1253@2 NA|NA|NA S Domain of unknown function DUF21 gnl|extdb|FAM19036-p1-1.1_002706 1171373.PACID_04350 8.9e-98 362.8 Propionibacteriales Bacteria 2GJJZ@201174,4DUFM@85009,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_002707 1171373.PACID_04340 9.1e-128 463.0 Actinobacteria Bacteria 2EQPB@1,2GUC0@201174,33I99@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002708 1171373.PACID_04330 4.6e-94 350.5 Actinobacteria Bacteria 2BPPW@1,2H77V@201174,32IH4@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002709 1171373.PACID_04320 1e-140 506.1 Actinobacteria Bacteria 2GQMY@201174,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase gnl|extdb|FAM19036-p1-1.1_002710 1171373.PACID_04310 0.0 1202.6 Actinobacteria tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 2I36F@201174,COG0021@1,COG0021@2 NA|NA|NA G Belongs to the transketolase family gnl|extdb|FAM19036-p1-1.1_002711 1171373.PACID_04300 2.1e-73 281.6 Bacteria Bacteria 2DN2A@1,32V51@2 NA|NA|NA S Protein of unknown function (DUF4232) gnl|extdb|FAM19036-p1-1.1_002714 1171373.PACID_04280 8.9e-195 686.0 Propionibacteriales Z012_01000 1.1.1.14,1.1.1.9 ko:K00008,ko:K05351 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC7@201174,4DR90@85009,COG1063@1,COG1063@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM19036-p1-1.1_002716 1171373.PACID_04260 3.5e-174 617.5 Propionibacteriales Bacteria 2BBBH@1,2H9TJ@201174,324UE@2,4DVWX@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002717 1171373.PACID_04250 8.4e-254 882.5 Propionibacteriales Bacteria 2GKKW@201174,4DNTG@85009,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain gnl|extdb|FAM19036-p1-1.1_002718 1171373.PACID_04240 3e-88 331.3 Bacteria Bacteria 2DN2A@1,32V51@2 NA|NA|NA S Protein of unknown function (DUF4232) gnl|extdb|FAM19036-p1-1.1_002719 1171373.PACID_04230 1e-142 512.7 Actinobacteria 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 2GIXX@201174,COG1119@1,COG1119@2 NA|NA|NA P ABC transporter gnl|extdb|FAM19036-p1-1.1_002720 1171373.PACID_04220 4.6e-134 483.8 Propionibacteriales dnaQ2 2.7.7.7 ko:K02337,ko:K02342,ko:K09951 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03400 Bacteria 2I2KI@201174,4DSDP@85009,COG0847@1,COG0847@2 NA|NA|NA L Exonuclease gnl|extdb|FAM19036-p1-1.1_002721 1171373.PACID_04210 1.4e-281 974.9 Actinobacteria phoN Bacteria 2I3WQ@201174,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily gnl|extdb|FAM19036-p1-1.1_002722 478801.Ksed_01810 3.5e-157 561.6 Actinobacteria 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IB2P@201174,COG0640@1,COG0640@2,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal gnl|extdb|FAM19036-p1-1.1_002723 1171373.PACID_04200 1.8e-240 838.2 Propionibacteriales rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 ko:K07478 ko00000 Bacteria 2GKDP@201174,4DP5Q@85009,COG2256@1,COG2256@2 NA|NA|NA L MgsA AAA+ ATPase C terminal gnl|extdb|FAM19036-p1-1.1_002724 1292373.H640_01443 7.2e-63 247.3 Propionibacteriales iclR_5 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 Bacteria 2HVQ8@201174,4DVAA@85009,COG1414@1,COG1414@2 NA|NA|NA K helix_turn_helix isocitrate lyase regulation gnl|extdb|FAM19036-p1-1.1_002726 267747.PPA2167 7.4e-140 503.8 Propionibacteriales amaB 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDE@201174,4DN05@85009,COG0624@1,COG0624@2 NA|NA|NA E Peptidase family M20/M25/M40 gnl|extdb|FAM19036-p1-1.1_002727 1292373.H640_01515 1.1e-136 493.4 Propionibacteriales hutF 3.5.3.13 ko:K05603 ko00340,map00340 R02286 RC00682 ko00000,ko00001,ko01000 Bacteria 2GZ2Q@201174,4DQ0Z@85009,COG0402@1,COG0402@2 NA|NA|NA F Amidohydrolase family gnl|extdb|FAM19036-p1-1.1_002728 1449355.JQNR01000005_gene2486 1.4e-143 516.2 Actinobacteria hutI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJH4@201174,COG1228@1,COG1228@2 NA|NA|NA Q Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway gnl|extdb|FAM19036-p1-1.1_002729 1176165.CAJD01000009_gene289 2.1e-214 751.9 Brevibacteriaceae hutH 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZW@201174,4F92I@85019,COG2986@1,COG2986@2 NA|NA|NA E Aromatic amino acid lyase gnl|extdb|FAM19036-p1-1.1_002730 1132441.KI519455_gene3281 5.7e-42 178.7 Micrococcaceae hutH2 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 Bacteria 1WCIS@1268,2GK17@201174,COG2986@1,COG2986@2 NA|NA|NA E Aromatic amino acid lyase gnl|extdb|FAM19036-p1-1.1_002732 1171373.PACID_04190 2.9e-81 308.9 Bacteria lacI5 ko:K02529 ko00000,ko03000 Bacteria COG1609@1,COG1609@2 NA|NA|NA K purine nucleotide biosynthetic process gnl|extdb|FAM19036-p1-1.1_002733 1171373.PACID_04170 3.5e-166 590.9 Propionibacteriales Bacteria 2GK0F@201174,4DPFS@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM19036-p1-1.1_002734 1171373.PACID_04160 1.2e-103 382.5 Propionibacteriales 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 2GNNY@201174,4DP9C@85009,COG1064@1,COG1064@2 NA|NA|NA S Zinc-binding dehydrogenase gnl|extdb|FAM19036-p1-1.1_002735 1171373.PACID_04150 5.8e-258 896.3 Propionibacteriales ko:K00375 ko00000,ko03000 Bacteria 2GITW@201174,4DPHM@85009,COG1167@1,COG1167@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor gnl|extdb|FAM19036-p1-1.1_002736 1171373.PACID_04140 3.1e-226 790.8 Propionibacteriales Bacteria 2GKDK@201174,4DQ69@85009,COG5441@1,COG5441@2 NA|NA|NA S Uncharacterised protein family (UPF0261) gnl|extdb|FAM19036-p1-1.1_002737 1171373.PACID_04130 4.1e-150 537.3 Propionibacteriales Bacteria 2GMW9@201174,4DTST@85009,COG5564@1,COG5564@2 NA|NA|NA S Phosphoenolpyruvate hydrolase-like gnl|extdb|FAM19036-p1-1.1_002738 1171373.PACID_04120 5e-39 166.8 Bacteria mshD GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189,2.7.4.1 ko:K00937,ko:K15520 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase gnl|extdb|FAM19036-p1-1.1_002739 1171373.PACID_04110 1.2e-205 722.2 Actinobacteria cI Bacteria 2ID8M@201174,COG1396@1,COG1396@2,COG2856@1,COG2856@2 NA|NA|NA K IrrE N-terminal-like domain gnl|extdb|FAM19036-p1-1.1_002740 1171373.PACID_04100 4.5e-180 637.1 Propionibacteriales ddhD Bacteria 2GKW0@201174,4DTF6@85009,COG0673@1,COG0673@2 NA|NA|NA S Homoserine dehydrogenase, NAD binding domain gnl|extdb|FAM19036-p1-1.1_002741 1171373.PACID_04080 1e-36 159.8 Actinobacteria Bacteria 2CJZ7@1,2IJU0@201174,2ZF1C@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002743 1171373.PACID_04060 5.6e-264 916.4 Propionibacteriales yjmB ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 2HD4Y@201174,4DWE6@85009,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM19036-p1-1.1_002744 754252.PFREUD_25120 4.3e-258 896.7 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_002745 1171373.PACID_04040 6.7e-95 353.2 Propionibacteriales ko:K07497 ko00000 Bacteria 2GKDY@201174,4DWS9@85009,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM19036-p1-1.1_002747 1122998.AUHZ01000032_gene59 2.6e-58 231.1 Actinobacteria arsR ko:K03892 ko00000,ko03000 Bacteria 2IQDH@201174,COG0640@1,COG0640@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002748 1122998.AUHZ01000032_gene60 5.1e-48 197.2 Actinobacteria arsD Bacteria 2DMHQ@1,2IQ7H@201174,32RMG@2 NA|NA|NA S Arsenical resistance operon trans-acting repressor gnl|extdb|FAM19036-p1-1.1_002749 1171373.PACID_04000 0.0 1120.9 Bacteria arsA 3.6.3.16 ko:K01551 ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 Bacteria COG0003@1,COG0003@2 NA|NA|NA P Pfam Anion-transporting ATPase gnl|extdb|FAM19036-p1-1.1_002750 1122997.AUDD01000035_gene2344 2.5e-144 518.1 Actinobacteria istB1 Bacteria 2H714@201174,COG1484@1,COG1484@2 NA|NA|NA L PFAM IstB domain protein ATP-binding protein gnl|extdb|FAM19036-p1-1.1_002752 1171373.PACID_03970 1.6e-85 322.0 Propionibacteriales 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 2IM6Z@201174,4DS6Y@85009,COG3871@1,COG3871@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase like gnl|extdb|FAM19036-p1-1.1_002753 1171373.PACID_03960 3.8e-210 737.3 Propionibacteriales sbnA 2.5.1.140 ko:K21949 R11705 ko00000,ko01000 Bacteria 2GK6J@201174,4DT4X@85009,COG0031@1,COG0031@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme gnl|extdb|FAM19036-p1-1.1_002754 1171373.PACID_03950 0.0 1153.7 Bacteria 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria COG4529@1,COG4529@2 NA|NA|NA M Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002755 1171373.PACID_03940 0.0 1119.8 Propionibacteriales 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GRW6@201174,4DV2G@85009,COG0019@1,COG0019@2 NA|NA|NA E Pyridoxal-dependent decarboxylase, pyridoxal binding domain gnl|extdb|FAM19036-p1-1.1_002756 1171373.PACID_34270 4.3e-236 823.5 Propionibacteriales Bacteria 2GM8F@201174,4DV2N@85009,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain gnl|extdb|FAM19036-p1-1.1_002757 1171373.PACID_03910 0.0 2152.9 Propionibacteriales lacZ 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GMAT@201174,4DPD7@85009,COG3250@1,COG3250@2 NA|NA|NA G Beta galactosidase small chain gnl|extdb|FAM19036-p1-1.1_002758 1171373.PACID_03900 1e-254 885.6 Actinobacteria gph ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 2HD4Y@201174,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM19036-p1-1.1_002759 1171373.PACID_03890 7.5e-191 672.9 Propionibacteriales galE1 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMCW@201174,4DP83@85009,COG1087@1,COG1087@2 NA|NA|NA M Polysaccharide biosynthesis protein gnl|extdb|FAM19036-p1-1.1_002762 1122998.AUHZ01000019_gene1687 5.9e-255 886.3 Propionibacteriales merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 2GJJK@201174,4DNX4@85009,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM19036-p1-1.1_002763 754252.PFREUD_24430 3.6e-171 607.8 Propionibacteriales ko:K07497 ko00000 Bacteria 2IDYA@201174,4DWSB@85009,COG2801@1,COG2801@2 NA|NA|NA L 4.4 Phage-related function gnl|extdb|FAM19036-p1-1.1_002764 1122998.AUHZ01000019_gene1691 0.0 2971.0 Actinobacteria Bacteria 2GKP2@201174,COG0286@1,COG0286@2,COG1111@1,COG1111@2,COG4889@1,COG4889@2 NA|NA|NA L helicase gnl|extdb|FAM19036-p1-1.1_002766 1171373.PACID_03760 1.2e-46 192.2 Actinobacteria Bacteria 2EP9H@1,2HBUH@201174,33GW8@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002767 1171373.PACID_10870 7.4e-236 822.8 Propionibacteriales Bacteria 2GM8F@201174,4DV2N@85009,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain gnl|extdb|FAM19036-p1-1.1_002769 1171373.PACID_15790 5.7e-236 823.2 Propionibacteriales Bacteria 2GM8F@201174,4DV2N@85009,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain gnl|extdb|FAM19036-p1-1.1_002770 754252.PFREUD_22970 9.2e-80 303.9 Actinobacteria ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,COG1609@1,COG1609@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002771 1321781.HMPREF1985_01034 2.5e-144 518.8 Negativicutes uhpC_2 ko:K07783 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.4.4,2.A.1.4.6 Bacteria 1TS33@1239,4H38R@909932,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM19036-p1-1.1_002772 500635.MITSMUL_04436 1e-190 674.1 Negativicutes Bacteria 1TPDA@1239,4H3JH@909932,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain gnl|extdb|FAM19036-p1-1.1_002775 1223543.GP2_034_00010 6.1e-75 287.3 Gordoniaceae Bacteria 2EF1H@1,2I8AU@201174,338UK@2,4GG3J@85026 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002776 1121019.AUMN01000007_gene2433 1.3e-79 302.8 Actinobacteria Bacteria 2IJ0U@201174,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002777 754252.PFREUD_25030 2.5e-234 817.8 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_002778 1171373.PACID_03730 9.3e-280 968.8 Propionibacteriales uxaC 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8PE@201174,4DQ45@85009,COG1904@1,COG1904@2 NA|NA|NA G Glucuronate isomerase gnl|extdb|FAM19036-p1-1.1_002779 1171373.PACID_03720 5.6e-291 1006.1 Propionibacteriales uxaA GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.7,4.4.1.24 ko:K01685,ko:K16845 ko00040,ko00270,ko01100,map00040,map00270,map01100 M00631 R01540,R07633 RC00543,RC01785 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJC8@201174,4DRFY@85009,COG2721@1,COG2721@2 NA|NA|NA G D-galactarate dehydratase / Altronate hydrolase, C terminus gnl|extdb|FAM19036-p1-1.1_002780 1171373.PACID_03710 6.4e-276 956.1 Actinobacteria uxaB 1.1.1.17,1.1.1.57,1.1.1.58 ko:K00009,ko:K00040,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00061,M00631 R02454,R02555,R02703 RC00085 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4F@201174,COG0246@1,COG0246@2 NA|NA|NA G Mannitol dehydrogenase gnl|extdb|FAM19036-p1-1.1_002781 1171373.PACID_03700 5.8e-175 620.2 Propionibacteriales ko:K02529,ko:K05499 ko00000,ko03000 Bacteria 2GMUU@201174,4DNP6@85009,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain gnl|extdb|FAM19036-p1-1.1_002782 1171373.PACID_03680 2.8e-79 301.2 Bacteria ko:K13641,ko:K21602 ko00000,ko03000 Bacteria COG1414@1,COG1414@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002783 1171373.PACID_03690 3.1e-46 191.8 Bacteria eda GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria COG0800@1,COG0800@2 NA|NA|NA G 2-dehydro-3-deoxy-phosphogluconate aldolase activity gnl|extdb|FAM19036-p1-1.1_002784 1380354.JIAN01000005_gene1216 3.2e-150 538.1 Cellulomonadaceae 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2HXTM@201174,4F0XK@85016,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM19036-p1-1.1_002785 1171373.PACID_03660 7.2e-242 842.8 Propionibacteriales manA GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,5.3.1.8,5.4.2.8 ko:K01809,ko:K01840,ko:K04035 ko00051,ko00520,ko00860,ko01100,ko01110,ko01130,map00051,map00520,map00860,map01100,map01110,map01130 M00114 R01818,R01819,R06265,R06266,R06267,R10068 RC00376,RC00408,RC00741,RC01491,RC01492,RC03042 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801 Bacteria 2GJXC@201174,4DPWV@85009,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase, class I gnl|extdb|FAM19036-p1-1.1_002786 1171373.PACID_03650 1.2e-249 868.6 Propionibacteriales Bacteria 2GXZI@201174,4DUPY@85009,COG2334@1,COG2334@2 NA|NA|NA S Phosphotransferase enzyme family gnl|extdb|FAM19036-p1-1.1_002787 1171373.PACID_03640 9.8e-244 849.0 Propionibacteriales patA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575 2.6.1.11,2.6.1.17,2.6.1.82 ko:K00821,ko:K05830,ko:K09251 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00031,M00763,M00845 R01155,R02283,R04475,R09778,R10932 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 iECIAI1_1343.ECIAI1_3220,iECSF_1327.ECSF_2916,iECs_1301.ECs3955,iZ_1308.Z4426 Bacteria 2GIYG@201174,4DTJ6@85009,COG4992@1,COG4992@2 NA|NA|NA H Aminotransferase class-III gnl|extdb|FAM19036-p1-1.1_002788 1171373.PACID_03630 9.5e-107 392.9 Propionibacteriales Bacteria 2IRD6@201174,4DST5@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002789 1171373.PACID_03620 1.2e-177 629.4 Propionibacteriales Bacteria 2GME5@201174,4DX19@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002790 1171373.PACID_03610 2.7e-169 601.3 Propionibacteriales proX ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iJN746.PP_2775 Bacteria 2GP39@201174,4DN5Y@85009,COG2113@1,COG2113@2 NA|NA|NA E Substrate binding domain of ABC-type glycine betaine transport system gnl|extdb|FAM19036-p1-1.1_002791 1171373.PACID_03590 6.2e-296 1022.7 Propionibacteriales betC 3.1.6.6 ko:K01133 ko00000,ko01000 Bacteria 2GJ8H@201174,4DS3H@85009,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase gnl|extdb|FAM19036-p1-1.1_002794 1171373.PACID_03510 1.4e-94 352.4 Actinobacteria Bacteria 2I9IY@201174,COG0739@1,COG0739@2 NA|NA|NA M peptidase gnl|extdb|FAM19036-p1-1.1_002795 1171373.PACID_03470 2.9e-246 857.4 Propionibacteriales xylB 1.1.1.57,2.7.1.17,2.7.1.5 ko:K00040,ko:K00848,ko:K00854,ko:K19168 ko00040,ko00051,ko01100,ko01120,map00040,map00051,map01100,map01120 M00014,M00061 R01639,R01902,R02454,R03014 RC00002,RC00017,RC00085,RC00538 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria 2GJDZ@201174,4DND9@85009,COG1070@1,COG1070@2 NA|NA|NA G FGGY family of carbohydrate kinases, N-terminal domain gnl|extdb|FAM19036-p1-1.1_002796 1171373.PACID_03460 3.9e-219 767.3 Actinobacteria GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 2IRY0@201174,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease gnl|extdb|FAM19036-p1-1.1_002797 1170318.PALO_01425 3.1e-237 827.4 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_002798 1171373.PACID_03280 0.0 1130.5 Propionibacteriales Bacteria 2GKHS@201174,4DSAI@85009,COG0210@1,COG0210@2 NA|NA|NA L UvrD/REP helicase N-terminal domain gnl|extdb|FAM19036-p1-1.1_002799 1171373.PACID_03270 0.0 3046.1 Propionibacteriales ko:K06877 ko00000 Bacteria 2GKQ2@201174,4DQ2E@85009,COG1201@1,COG1201@2,COG1205@1,COG1205@2 NA|NA|NA L Domain of unknown function (DUF1998) gnl|extdb|FAM19036-p1-1.1_002800 1171373.PACID_03260 0.0 2452.2 Propionibacteriales Bacteria 2GU5Z@201174,4DPNS@85009,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase gnl|extdb|FAM19036-p1-1.1_002805 706439.HMPREF9057_00400 1e-39 169.9 Actinobacteria ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 2ID5E@201174,4D5QC@85005,COG1487@1,COG1487@2 NA|NA|NA S Domain of unknown function (DUF4411) gnl|extdb|FAM19036-p1-1.1_002807 479431.Namu_1970 1.5e-12 78.6 Actinobacteria Bacteria 29XJ6@1,2GWVQ@201174,30JA6@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002808 1122997.AUDD01000022_gene2131 4e-44 184.9 Bacteria Bacteria COG0671@1,COG0671@2 NA|NA|NA I phosphatidate phosphatase activity gnl|extdb|FAM19036-p1-1.1_002809 1122998.AUHZ01000014_gene427 1.1e-62 246.1 Actinobacteria Bacteria 2IQFY@201174,COG3311@1,COG3311@2 NA|NA|NA K DNA binding domain gnl|extdb|FAM19036-p1-1.1_002811 1121272.KB903249_gene2016 4.1e-82 312.0 Micromonosporales ko:K19147 ko00000,ko02048 Bacteria 2GKET@201174,4DI7A@85008,COG4268@1,COG4268@2 NA|NA|NA L McrBC 5-methylcytosine restriction system component gnl|extdb|FAM19036-p1-1.1_002812 1077972.ARGLB_012_00160 1.1e-152 547.4 Micrococcaceae ko:K07452 ko00000,ko01000,ko02048 Bacteria 1W9XC@1268,2GM1I@201174,COG0464@1,COG0464@2,COG1401@1,COG1401@2 NA|NA|NA L AAA domain (dynein-related subfamily) gnl|extdb|FAM19036-p1-1.1_002813 1223545.GS4_26_00410 1.1e-124 453.0 Actinobacteria Bacteria 2I8KK@201174,COG0604@1,COG0604@2 NA|NA|NA C alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_002814 1171373.PACID_03190 2.7e-45 187.6 Bacteria Bacteria COG4453@1,COG4453@2 NA|NA|NA K Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002815 1171373.PACID_03180 4.1e-86 323.9 Actinobacteria yitI ko:K02348,ko:K07000 ko00000 Bacteria 2I5AH@201174,COG2153@1,COG2153@2 NA|NA|NA S Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_002817 1463857.JOFZ01000008_gene704 5e-11 73.6 Actinobacteria bglB 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 2GJ5H@201174,COG1361@1,COG1361@2,COG1472@1,COG1472@2 NA|NA|NA G hydrolase, family 3 gnl|extdb|FAM19036-p1-1.1_002818 1171373.PACID_03150 2.3e-66 258.1 Bacteria Bacteria 2DRG9@1,33BKJ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002819 1171373.PACID_03140 3e-133 481.1 Propionibacteriales ugpQ GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008889,GO:0016787,GO:0016788,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0047389,GO:0047395 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 iEC042_1314.EC042_3710,iEC55989_1330.EC55989_3857 Bacteria 2GNM5@201174,4DQNY@85009,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family gnl|extdb|FAM19036-p1-1.1_002820 1171373.PACID_03130 2.4e-195 688.0 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GM7M@201174,4DWNW@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_002821 1171373.PACID_03120 0.0 1484.2 Propionibacteriales rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 2GJJ1@201174,4DSZC@85009,COG3345@1,COG3345@2 NA|NA|NA G Glycosyl hydrolase family 36 N-terminal domain gnl|extdb|FAM19036-p1-1.1_002822 1171373.PACID_03110 2.6e-118 431.4 Actinobacteria mgtC ko:K07507 ko00000,ko02000 9.B.20 Bacteria 2GJF0@201174,COG1285@1,COG1285@2 NA|NA|NA S PFAM MgtC SapB transporter gnl|extdb|FAM19036-p1-1.1_002823 1171373.PACID_03100 2.8e-186 657.9 Propionibacteriales MA20_32325 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 2GMH2@201174,4DR6X@85009,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain gnl|extdb|FAM19036-p1-1.1_002824 1171373.PACID_03090 2e-154 551.6 Actinobacteria Bacteria 2IQ7M@201174,COG3375@1,COG3375@2 NA|NA|NA M carboxylic acid catabolic process gnl|extdb|FAM19036-p1-1.1_002825 1171373.PACID_03080 1e-128 466.1 Actinobacteria hexR ko:K19337 ko00000,ko03000 Bacteria 2INUK@201174,COG1737@1,COG1737@2 NA|NA|NA K SIS domain gnl|extdb|FAM19036-p1-1.1_002826 1171373.PACID_03070 1.9e-214 751.5 Propionibacteriales menC GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJJR@201174,4DQH1@85009,COG4948@1,COG4948@2 NA|NA|NA H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) gnl|extdb|FAM19036-p1-1.1_002828 1171373.PACID_03050 5.8e-160 570.1 Actinobacteria Bacteria 2GJQ7@201174,COG0656@1,COG0656@2 NA|NA|NA K aldo keto reductase gnl|extdb|FAM19036-p1-1.1_002829 1171373.PACID_03040 1.2e-214 752.3 Propionibacteriales Bacteria 2GNDG@201174,4DNDE@85009,COG4409@1,COG4409@2 NA|NA|NA G exo-alpha-(2->6)-sialidase activity gnl|extdb|FAM19036-p1-1.1_002830 1171373.PACID_03030 2e-166 591.7 Propionibacteriales uxuA 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 Bacteria 2H319@201174,4DS9M@85009,COG1312@1,COG1312@2 NA|NA|NA G Catalyzes the dehydration of D-mannonate gnl|extdb|FAM19036-p1-1.1_002831 1171373.PACID_03020 2.9e-265 920.6 Propionibacteriales mtlD GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.17,1.1.1.57,1.1.1.58 ko:K00009,ko:K00040,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00061,M00631 R02454,R02555,R02703 RC00085 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4F@201174,4DPWW@85009,COG0246@1,COG0246@2 NA|NA|NA G Mannitol dehydrogenase Rossmann domain gnl|extdb|FAM19036-p1-1.1_002832 1171373.PACID_03010 3.6e-276 956.8 Propionibacteriales uxaC 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8PE@201174,4DQ45@85009,COG1904@1,COG1904@2 NA|NA|NA G Glucuronate isomerase gnl|extdb|FAM19036-p1-1.1_002833 1171373.PACID_03000 3.4e-83 314.3 Propionibacteriales ko:K02529,ko:K05499 ko00000,ko03000 Bacteria 2GMUU@201174,4DNP6@85009,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain gnl|extdb|FAM19036-p1-1.1_002835 1171373.PACID_02990 7e-281 972.6 Actinobacteria uxuT ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 2IAMT@201174,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM19036-p1-1.1_002836 1122998.AUHZ01000018_gene1266 2.2e-287 994.2 Propionibacteriales aldB GO:0003674,GO:0003824,GO:0004029,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0010033,GO:0016020,GO:0016043,GO:0016491,GO:0016620,GO:0016903,GO:0022607,GO:0033554,GO:0033723,GO:0035821,GO:0042221,GO:0042493,GO:0043207,GO:0043933,GO:0044003,GO:0044085,GO:0044403,GO:0044419,GO:0044464,GO:0045471,GO:0046677,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0075136,GO:0097305,GO:1901700 1.2.1.3 ko:K00128,ko:K00138,ko:K18370 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00640,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00640,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R10703 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00545,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3626,iSFxv_1172.SFxv_3952,iS_1188.S4142 Bacteria 2GIWZ@201174,4DPJR@85009,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_002837 1171373.PACID_02970 5.6e-205 719.9 Propionibacteriales 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 2GNNY@201174,4DP9C@85009,COG1064@1,COG1064@2 NA|NA|NA S Zinc-binding dehydrogenase gnl|extdb|FAM19036-p1-1.1_002838 1171373.PACID_02960 2.4e-297 1027.3 Actinobacteria pepD ko:K08659 ko00000,ko01000,ko01002 Bacteria 2GM80@201174,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase gnl|extdb|FAM19036-p1-1.1_002839 1171373.PACID_02950 0.0 1135.2 Actinobacteria Bacteria 2BY1P@1,2IKCK@201174,33HUJ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002840 1171373.PACID_02930 2.8e-244 850.9 Actinobacteria Bacteria 2BY1P@1,2IKCK@201174,33HUJ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002841 1171373.PACID_02920 1.2e-103 383.6 Bacteria ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria COG1566@1,COG1566@2,COG3942@1,COG3942@2 NA|NA|NA S pathogenesis gnl|extdb|FAM19036-p1-1.1_002842 1171373.PACID_02910 1.1e-189 669.1 Propionibacteriales Bacteria 2GJ5Q@201174,4DTZI@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_002846 1171373.PACID_02860 0.0 1402.9 Actinobacteria Bacteria 2GMAT@201174,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family gnl|extdb|FAM19036-p1-1.1_002848 1171373.PACID_02840 5.9e-182 643.3 Bacteria drp35 GO:0005575,GO:0005576 3.1.1.17 ko:K01053,ko:K02352 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria COG3386@1,COG3386@2 NA|NA|NA G gluconolactonase activity gnl|extdb|FAM19036-p1-1.1_002849 1171373.PACID_02830 2.9e-103 381.3 Propionibacteriales thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00788,ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iYO844.BSU38290 Bacteria 2GKCN@201174,4DSCS@85009,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) gnl|extdb|FAM19036-p1-1.1_002850 1171373.PACID_02820 1.9e-164 585.1 Propionibacteriales thiD 2.5.1.3,2.7.1.49,2.7.4.7 ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R04509,R10712 RC00002,RC00017,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKZM@201174,4DR48@85009,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase gnl|extdb|FAM19036-p1-1.1_002853 1171373.PACID_02790 4.7e-82 310.5 Propionibacteriales moaC 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 2IHR6@201174,4DQPG@85009,COG0315@1,COG0315@2 NA|NA|NA H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) gnl|extdb|FAM19036-p1-1.1_002854 1171373.PACID_02780 1.7e-221 775.0 Actinobacteria moeA 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 2GJC3@201174,COG0303@1,COG0303@2 NA|NA|NA H Molybdenum cofactor synthesis domain protein gnl|extdb|FAM19036-p1-1.1_002855 1171373.PACID_02770 5.4e-71 273.5 Propionibacteriales moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.80,2.8.1.11,2.8.1.12 ko:K03635,ko:K21147 ko00790,ko01100,ko04122,map00790,map01100,map04122 R07459,R07461,R09395 RC00043,RC02507 ko00000,ko00001,ko01000 Bacteria 2IQ9F@201174,4DR9R@85009,COG0314@1,COG0314@2 NA|NA|NA H MoaE protein gnl|extdb|FAM19036-p1-1.1_002856 1171373.PACID_02760 1.5e-36 158.3 Bacteria moaD 2.8.1.12 ko:K03636,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria COG1977@1,COG1977@2 NA|NA|NA H Mo-molybdopterin cofactor metabolic process gnl|extdb|FAM19036-p1-1.1_002857 1171373.PACID_02750 3.3e-173 614.4 Propionibacteriales moaA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 ko:K03639,ko:K20967 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394,R11372 RC03420,RC03425 ko00000,ko00001,ko01000 Bacteria 2GN0V@201174,4DP3D@85009,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate gnl|extdb|FAM19036-p1-1.1_002858 1171373.PACID_02740 4.7e-134 483.8 Bacteria Bacteria COG2345@1,COG2345@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002859 1171373.PACID_02730 1.3e-131 475.7 Propionibacteriales narI GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 ko:K00370,ko:K00374,ko:K02575 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00615,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.8,5.A.3.1 iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897 Bacteria 2GJVI@201174,4DP8B@85009,COG2181@1,COG2181@2 NA|NA|NA C Nitrate reductase gamma subunit gnl|extdb|FAM19036-p1-1.1_002860 1171373.PACID_02720 5e-122 443.7 Propionibacteriales narJ GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 ko:K00373,ko:K17052 ko02020,map02020 ko00000,ko00001,ko02000 5.A.3.8 iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,iYO844.BSU37260,ic_1306.c1687 Bacteria 2IPTW@201174,4DWUK@85009,COG2180@1,COG2180@2 NA|NA|NA C Nitrate reductase delta subunit gnl|extdb|FAM19036-p1-1.1_002861 1171373.PACID_02710 8.5e-311 1072.0 Propionibacteriales narH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189 Bacteria 2GJ8P@201174,4DPZ0@85009,COG1140@1,COG1140@2 NA|NA|NA C Respiratory nitrate reductase beta C-terminal gnl|extdb|FAM19036-p1-1.1_002862 1171373.PACID_02700 0.0 2604.3 Propionibacteriales narG 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 Bacteria 2GKZU@201174,4DNS8@85009,COG5013@1,COG5013@2 NA|NA|NA C Molybdopterin oxidoreductase Fe4S4 domain gnl|extdb|FAM19036-p1-1.1_002863 765123.HMPREF9621_02167 6.7e-202 709.9 Actinobacteria narK ko:K02575 ko00910,map00910 M00615 ko00000,ko00001,ko00002,ko02000 2.A.1.8 Bacteria 2GJ1I@201174,COG2223@1,COG2223@2 NA|NA|NA P Major Facilitator gnl|extdb|FAM19036-p1-1.1_002864 1171373.PACID_02660 1.5e-222 778.5 Bacteria eryK Bacteria COG2124@1,COG2124@2 NA|NA|NA Q cytochrome p450 gnl|extdb|FAM19036-p1-1.1_002865 1171373.PACID_02650 4.7e-114 417.2 Propionibacteriales Bacteria 2I8FY@201174,4DUNH@85009,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain gnl|extdb|FAM19036-p1-1.1_002866 1171373.PACID_02640 3.5e-199 700.7 Actinobacteria benC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 ko:K05784,ko:K11311 ko00362,ko00364,ko00622,ko00627,ko01100,ko01120,ko01220,map00362,map00364,map00622,map00627,map01100,map01120,map01220 M00551,M00637 R00823,R00825,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00192,RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 2GQJX@201174,COG1018@1,COG1018@2 NA|NA|NA C Oxidoreductase FAD-binding domain gnl|extdb|FAM19036-p1-1.1_002868 1171373.PACID_02620 4.4e-106 390.6 Propionibacteriales mobA 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 R11581 ko00000,ko00001,ko01000 Bacteria 2GJVE@201174,4DSFW@85009,COG0746@1,COG0746@2 NA|NA|NA H MobA-like NTP transferase domain gnl|extdb|FAM19036-p1-1.1_002869 1171373.PACID_02610 1.4e-50 205.3 Propionibacteriales ko:K07171 ko00000,ko01000,ko02048 Bacteria 2IR5D@201174,4DVPS@85009,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system gnl|extdb|FAM19036-p1-1.1_002870 1171373.PACID_02600 3.4e-30 137.1 Actinobacteria Bacteria 2DS09@1,2IR3C@201174,33DY5@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002871 1171373.PACID_02590 2.6e-83 314.7 Actinobacteria mog GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.75,2.8.1.12,4.99.1.12 ko:K03635,ko:K03831,ko:K09121 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395,R09726 RC00002,RC02507 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1969,iECABU_c1320.ECABU_c00100,iECED1_1282.ECED1_0009,iECNA114_1301.ECNA114_4653,iECP_1309.ECP_0010,iECS88_1305.ECS88_0010,iECSF_1327.ECSF_0009,iECUMN_1333.ECUMN_0010,iEcSMS35_1347.EcSMS35_0008,iLF82_1304.LF82_1379,iNRG857_1313.NRG857_00050,iUMN146_1321.UM146_22820 Bacteria 2H57U@201174,COG0521@1,COG0521@2 NA|NA|NA H Molybdopterin binding domain protein gnl|extdb|FAM19036-p1-1.1_002872 1171373.PACID_02580 4.4e-65 253.8 Actinobacteria ko:K02019 ko00000,ko03000 Bacteria 2IKQV@201174,COG3585@1,COG3585@2 NA|NA|NA H DNA binding domain gnl|extdb|FAM19036-p1-1.1_002873 1171373.PACID_02570 7.3e-136 490.0 Propionibacteriales modA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 ko:K02020 ko02010,map02010 M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.8 Bacteria 2GMPF@201174,4DQXM@85009,COG0725@1,COG0725@2 NA|NA|NA P Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_002874 1171373.PACID_02560 0.0 1084.7 Actinobacteria modB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.10.1.1,3.6.3.29,3.6.3.55 ko:K02017,ko:K02018,ko:K03750,ko:K15496,ko:K15497 ko00790,ko01100,ko02010,map00790,map01100,map02010 M00189,M00423 R09735,R10531 RC00002,RC03462 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.5,3.A.1.8 iECO103_1326.ECO103_0752 Bacteria 2GJFB@201174,COG3842@1,COG3842@2,COG4149@1,COG4149@2 NA|NA|NA P Molybdate ABC transporter gnl|extdb|FAM19036-p1-1.1_002875 1171373.PACID_02550 1.8e-176 625.2 Propionibacteriales ddpB ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GMR8@201174,4DRF6@85009,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002876 1171373.PACID_02540 4.2e-142 510.8 Propionibacteriales ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GN0C@201174,4DR4G@85009,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002878 1171373.PACID_02520 0.0 1099.3 Propionibacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ4B@201174,4DREA@85009,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle gnl|extdb|FAM19036-p1-1.1_002879 1171373.PACID_02510 4.7e-201 706.8 Propionibacteriales yqjG GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7,2.5.1.18 ko:K00799,ko:K07393 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 iECW_1372.ECW_m3373,iWFL_1372.ECW_m3373 Bacteria 2GIXK@201174,4DNXR@85009,COG0435@1,COG0435@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain gnl|extdb|FAM19036-p1-1.1_002880 1171373.PACID_02500 1.1e-211 742.3 Propionibacteriales 1.8.5.7 ko:K07393 ko00000,ko01000 Bacteria 2GIXK@201174,4DNXR@85009,COG0435@1,COG0435@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain gnl|extdb|FAM19036-p1-1.1_002881 1171373.PACID_02490 6.1e-207 726.5 Propionibacteriales Bacteria 2GIXK@201174,4DNXR@85009,COG0435@1,COG0435@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain gnl|extdb|FAM19036-p1-1.1_002882 1171373.PACID_02480 8.7e-249 865.9 Bacteria 1.8.5.7 ko:K07393 ko00000,ko01000 Bacteria COG0435@1,COG0435@2 NA|NA|NA O Glutathione S-transferase gnl|extdb|FAM19036-p1-1.1_002883 1206730.BAGA01000056_gene2720 3e-38 165.2 Nocardiaceae Bacteria 2I7H2@201174,4G9SQ@85025,COG1569@1,COG1569@2 NA|NA|NA S PIN domain gnl|extdb|FAM19036-p1-1.1_002885 1121353.H924_12865 3.4e-222 777.7 Corynebacteriaceae Bacteria 22KVX@1653,2GM4J@201174,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM19036-p1-1.1_002886 1121353.H924_12870 2e-111 408.7 Corynebacteriaceae ko:K02315 ko00000,ko03032 Bacteria 22MBX@1653,2IA1S@201174,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein gnl|extdb|FAM19036-p1-1.1_002887 1171373.PACID_02460 9.7e-51 205.7 Propionibacteriales ko:K06975 ko00000 Bacteria 2GQNP@201174,4DSKE@85009,COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase gnl|extdb|FAM19036-p1-1.1_002888 1171373.PACID_02450 2.1e-39 167.9 Actinobacteria Bacteria 2E8MQ@1,2GRGI@201174,332Z5@2 NA|NA|NA S Ribbon-helix-helix protein, copG family gnl|extdb|FAM19036-p1-1.1_002890 1171373.PACID_02440 3.2e-12 77.0 Bacteria ko:K18918 ko00000,ko02048,ko03000 Bacteria COG4710@1,COG4710@2 NA|NA|NA DJ CopG domain protein DNA-binding domain protein gnl|extdb|FAM19036-p1-1.1_002891 1032480.MLP_13940 2.7e-45 188.3 Actinobacteria Bacteria 2C03A@1,2GMCC@201174,2Z86B@2 NA|NA|NA S Domain of unknown function (DUF4291) gnl|extdb|FAM19036-p1-1.1_002893 1122998.AUHZ01000024_gene1328 0.0 1957.2 Propionibacteriales Bacteria 2GK1D@201174,4DT0U@85009,COG3209@1,COG3209@2 NA|NA|NA M RHS Repeat gnl|extdb|FAM19036-p1-1.1_002894 1449976.KALB_5282 5e-93 349.4 Pseudonocardiales Bacteria 2GK5H@201174,4E027@85010,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family gnl|extdb|FAM19036-p1-1.1_002895 414996.IL38_23100 7.1e-33 146.7 Actinobacteria Bacteria 2E13J@1,2H03T@201174,32WIZ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002896 1122998.AUHZ01000024_gene1328 2.1e-135 489.6 Propionibacteriales Bacteria 2GK1D@201174,4DT0U@85009,COG3209@1,COG3209@2 NA|NA|NA M RHS Repeat gnl|extdb|FAM19036-p1-1.1_002897 1184609.KILIM_079_00250 7.7e-28 130.6 Actinobacteria Bacteria 2B4PM@1,2GYYR@201174,31XFW@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002898 414996.IL38_23100 4.7e-29 134.0 Actinobacteria Bacteria 2E13J@1,2H03T@201174,32WIZ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002899 1171373.PACID_02400 1.4e-90 339.0 Propionibacteriales dps ko:K04047 ko00000,ko03036 Bacteria 2IFDP@201174,4DQZR@85009,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family gnl|extdb|FAM19036-p1-1.1_002900 1171373.PACID_02390 1.1e-119 436.0 Propionibacteriales flpA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 2IKTT@201174,4DVJ5@85009,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein gnl|extdb|FAM19036-p1-1.1_002901 1171373.PACID_02380 8.6e-37 159.1 Actinobacteria ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 2GQMZ@201174,COG2608@1,COG2608@2 NA|NA|NA P copper chaperone gnl|extdb|FAM19036-p1-1.1_002902 1171373.PACID_02370 0.0 1163.3 Actinobacteria copA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 2GIRF@201174,COG2217@1,COG2217@2 NA|NA|NA P Heavy metal translocating P-type atpase gnl|extdb|FAM19036-p1-1.1_002904 1171373.PACID_02350 2.8e-66 257.7 Actinobacteria yeaO Bacteria 2IQC0@201174,COG3189@1,COG3189@2 NA|NA|NA K Protein of unknown function, DUF488 gnl|extdb|FAM19036-p1-1.1_002907 1171373.PACID_02320 1.5e-117 428.7 Bacteria Bacteria COG2345@1,COG2345@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002909 1157635.KB892013_gene2147 1.4e-128 466.8 Actinobacteria ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,COG1123@1,COG4172@2 NA|NA|NA P ATPase activity gnl|extdb|FAM19036-p1-1.1_002911 1171373.PACID_02270 3.1e-209 734.2 Propionibacteriales pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iJN678.pfkA Bacteria 2GK6W@201174,4DPJ3@85009,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis gnl|extdb|FAM19036-p1-1.1_002912 1171373.PACID_02260 9.8e-121 439.5 Bacteria ko:K07108,ko:K16247 ko00000,ko03000 Bacteria COG2522@1,COG2522@2 NA|NA|NA O sequence-specific DNA binding gnl|extdb|FAM19036-p1-1.1_002913 1232429.CBLL010000003_gene1793 2.1e-12 79.0 Micrococcaceae Bacteria 1WABD@1268,2E3HJ@1,2GQV8@201174,32YG5@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002914 1171373.PACID_02240 7.7e-117 426.4 Bacteria Bacteria COG4339@1,COG4339@2 NA|NA|NA L protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_002915 1171373.PACID_02230 1.4e-278 964.9 Propionibacteriales gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4DNDH@85009,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_002916 1171373.PACID_02220 3.2e-136 491.1 Propionibacteriales phnL ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GM25@201174,4DQRF@85009,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_002917 1171373.PACID_02210 4.1e-208 730.7 Actinobacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKF3@201174,COG0577@1,COG0577@2 NA|NA|NA V Efflux ABC transporter, permease protein gnl|extdb|FAM19036-p1-1.1_002918 1171373.PACID_02200 5.2e-278 963.0 Propionibacteriales femD 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2IB2T@201174,4DWT1@85009,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, C-terminal domain gnl|extdb|FAM19036-p1-1.1_002919 1171373.PACID_02190 1.6e-194 685.3 Actinobacteria oadB 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 Bacteria 2IF5V@201174,COG1883@1,COG1883@2 NA|NA|NA C Na+-transporting oxaloacetate decarboxylase beta subunit gnl|extdb|FAM19036-p1-1.1_002921 1171373.PACID_02170 3.5e-59 234.2 Bacteria oadG GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 Bacteria COG3630@1,COG3630@2 NA|NA|NA C sodium ion export across plasma membrane gnl|extdb|FAM19036-p1-1.1_002923 1171373.PACID_02150 0.0 1353.6 Propionibacteriales yfiQ GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 ko:K01905,ko:K09181,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 Bacteria 2GKN1@201174,4DTV0@85009,COG0045@1,COG0045@2,COG1042@1,COG1042@2 NA|NA|NA H ATP-grasp domain gnl|extdb|FAM19036-p1-1.1_002924 1171373.PACID_02140 3.7e-47 193.7 Propionibacteriales acyP 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 Bacteria 2HZEW@201174,4DSGP@85009,COG1254@1,COG1254@2 NA|NA|NA C Acylphosphatase gnl|extdb|FAM19036-p1-1.1_002928 1171373.PACID_02100 0.0 1124.0 Propionibacteriales malS GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 R00214 RC00105 ko00000,ko00001,ko01000 Bacteria 2GJAJ@201174,4DTGZ@85009,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme, NAD binding domain gnl|extdb|FAM19036-p1-1.1_002929 1075090.GOAMR_20_02550 1.2e-19 102.8 Gordoniaceae Bacteria 2I1U7@201174,4GF9V@85026,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002932 1171373.PACID_02070 8.3e-128 463.0 Propionibacteriales mntR ko:K03709,ko:K04758,ko:K09819 M00243 ko00000,ko00002,ko02000,ko03000 3.A.1.15 Bacteria 2GK7P@201174,4DVDS@85009,COG1321@1,COG1321@2,COG1918@1,COG1918@2 NA|NA|NA K FeoA gnl|extdb|FAM19036-p1-1.1_002933 1171373.PACID_02060 1.1e-229 802.4 Propionibacteriales mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 2GJSM@201174,4DSP2@85009,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein gnl|extdb|FAM19036-p1-1.1_002934 1171373.PACID_02050 6.2e-211 740.0 Propionibacteriales nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 2GKIK@201174,4DNGP@85009,COG3004@1,COG3004@2 NA|NA|NA P ) H( ) antiporter that extrudes sodium in exchange for external protons gnl|extdb|FAM19036-p1-1.1_002935 1171373.PACID_02040 0.0 1172.5 Propionibacteriales Bacteria 2GJ09@201174,4DP60@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM19036-p1-1.1_002936 1171373.PACID_02030 2.1e-100 371.7 Propionibacteriales Bacteria 2H015@201174,4DSPS@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002938 1171373.PACID_02010 1e-96 359.4 Propionibacteriales 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 2GMZ5@201174,4DQQN@85009,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent gnl|extdb|FAM19036-p1-1.1_002939 1171373.PACID_02000 0.0 1251.9 Propionibacteriales mrcB 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K15539 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4DMYZ@85009,COG0744@1,COG0744@2,COG3266@1,COG3266@2 NA|NA|NA M Transglycosylase gnl|extdb|FAM19036-p1-1.1_002940 1171373.PACID_01990 6.5e-176 623.2 Propionibacteriales 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2I66G@201174,4DTX9@85009,COG0111@1,COG0111@2 NA|NA|NA C D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain gnl|extdb|FAM19036-p1-1.1_002941 1171373.PACID_01980 0.0 1207.2 Actinobacteria Bacteria 2GIZG@201174,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 gnl|extdb|FAM19036-p1-1.1_002942 1171373.PACID_01970 1.2e-219 768.8 Actinobacteria Bacteria 2GIZG@201174,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferase, group 1 gnl|extdb|FAM19036-p1-1.1_002943 1171373.PACID_01960 2.4e-192 679.1 Propionibacteriales yhgE ko:K01421 ko00000 Bacteria 2GKEM@201174,4DQ2G@85009,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein gnl|extdb|FAM19036-p1-1.1_002944 1171373.PACID_01950 0.0 1750.3 Propionibacteriales ko:K02049,ko:K02068,ko:K02074,ko:K06994,ko:K09817 ko02010,map02010 M00188,M00211,M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5,3.A.1.16,3.A.1.17 Bacteria 2GJ5A@201174,4DNDC@85009,COG1121@1,COG1121@2,COG2409@1,COG2409@2 NA|NA|NA P MMPL family gnl|extdb|FAM19036-p1-1.1_002945 1171373.PACID_01930 1.5e-101 375.6 Propionibacteriales Bacteria 2HGB0@201174,4DW3N@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002949 1171373.PACID_01890 6.9e-139 500.0 Propionibacteriales thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 Bacteria 2GM62@201174,4DP6Q@85009,COG2022@1,COG2022@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S gnl|extdb|FAM19036-p1-1.1_002950 1171373.PACID_01880 4.9e-37 159.8 Propionibacteriales thiS ko:K03154,ko:K03636 ko04122,map04122 ko00000,ko00001 Bacteria 2HZFM@201174,4DSM2@85009,COG2104@1,COG2104@2 NA|NA|NA H ThiS family gnl|extdb|FAM19036-p1-1.1_002951 1171373.PACID_01870 1.1e-167 595.9 Bacteria Bacteria COG0596@1,COG0596@2 NA|NA|NA S hydrolase activity, acting on ester bonds gnl|extdb|FAM19036-p1-1.1_002952 1171373.PACID_01860 1.8e-68 266.2 Actinobacteria rlpA ko:K03642,ko:K07184,ko:K21688 ko00000 Bacteria 2GSPY@201174,COG0797@1,COG0797@2,COG3103@1,COG3103@2 NA|NA|NA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides gnl|extdb|FAM19036-p1-1.1_002954 1171373.PACID_01840 4.2e-20 104.4 Actinobacteria Bacteria 2DXTX@1,2H7JM@201174,346J1@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002956 1171373.PACID_01820 8.7e-51 206.1 Actinobacteria exsI Bacteria 2GTNT@201174,COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM19036-p1-1.1_002957 1171373.PACID_01810 8e-154 549.7 Actinobacteria Bacteria 2IFJ3@201174,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain gnl|extdb|FAM19036-p1-1.1_002958 1171373.PACID_01800 1.1e-158 565.8 Actinobacteria yeaE GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.21 ko:K00011 ko00040,ko00051,ko00052,ko00561,ko00790,ko01100,map00040,map00051,map00052,map00561,map00790,map01100 R01036,R01041,R01093,R01095,R01431,R01758,R01759,R01787,R02531,R02577,R04285,R11764 RC00099,RC00108,RC00133,RC00205,RC00670 ko00000,ko00001,ko01000 iAF1260.b1781,iB21_1397.B21_01738,iBWG_1329.BWG_1594,iECBD_1354.ECBD_1863,iECB_1328.ECB_01750,iECDH10B_1368.ECDH10B_1919,iECDH1ME8569_1439.ECDH1ME8569_1725,iECD_1391.ECD_01750,iEcDH1_1363.EcDH1_1861,iEcHS_1320.EcHS_A1866,iEcolC_1368.EcolC_1851,iJO1366.b1781,iY75_1357.Y75_RS09335 Bacteria 2H09X@201174,COG0656@1,COG0656@2 NA|NA|NA S aldo keto reductase gnl|extdb|FAM19036-p1-1.1_002959 1171373.PACID_01780 5.9e-231 806.6 Actinobacteria Bacteria 2ICQK@201174,2Z7NA@2,arCOG09719@1 NA|NA|NA S Protein of unknown function (DUF3100) gnl|extdb|FAM19036-p1-1.1_002961 1171373.PACID_01760 1e-187 662.5 Actinobacteria Bacteria 2IGHA@201174,COG1522@1,COG1522@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM19036-p1-1.1_002962 1171373.PACID_01750 3.9e-83 313.9 Actinobacteria Bacteria 2C97V@1,2GY8Z@201174,31X1K@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002963 1171373.PACID_01740 1.4e-146 525.8 Propionibacteriales ytnM ko:K07090 ko00000 Bacteria 2GNPE@201174,4DPCI@85009,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE gnl|extdb|FAM19036-p1-1.1_002964 1171373.PACID_01730 8.8e-246 855.9 Propionibacteriales cysN 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDX@201174,4DPIP@85009,COG2895@1,COG2895@2 NA|NA|NA P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily gnl|extdb|FAM19036-p1-1.1_002965 1171373.PACID_01720 5.8e-177 626.7 Propionibacteriales cysD 1.8.4.10,1.8.4.8,2.7.7.4 ko:K00390,ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R02021,R04929 RC00007,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN85@201174,4DPJX@85009,COG0175@1,COG0175@2 NA|NA|NA EH Sulfate adenylyltransferase gnl|extdb|FAM19036-p1-1.1_002966 1171373.PACID_01710 5.2e-125 453.8 Propionibacteriales cysH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2392 Bacteria 2GJ3Z@201174,4DPGD@85009,COG0175@1,COG0175@2 NA|NA|NA EH Belongs to the PAPS reductase family. CysH subfamily gnl|extdb|FAM19036-p1-1.1_002969 1171373.PACID_01680 1.3e-92 345.9 Propionibacteriales 1.11.1.15 ko:K03386,ko:K03564,ko:K16922 ko04214,map04214 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 2IGFI@201174,4DRG7@85009,COG1225@1,COG1225@2 NA|NA|NA O Redoxin gnl|extdb|FAM19036-p1-1.1_002970 1171373.PACID_01670 8.5e-139 500.0 Propionibacteriales Bacteria 2GMXW@201174,4DTAU@85009,COG0785@1,COG0785@2 NA|NA|NA O Cytochrome C biogenesis protein transmembrane region gnl|extdb|FAM19036-p1-1.1_002972 1171373.PACID_01650 2.7e-24 117.1 Actinobacteria Bacteria 2BSCJ@1,2GZCT@201174,32MEG@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002975 1171373.PACID_01620 7.4e-132 476.5 Propionibacteriales Bacteria 2GJE6@201174,4DNSE@85009,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver gnl|extdb|FAM19036-p1-1.1_002976 1171373.PACID_01610 3.4e-200 704.1 Propionibacteriales tcsS4 2.7.13.3 ko:K07642,ko:K10819 ko02020,map02020 M00450,M00645,M00646,M00648 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GIX7@201174,4DP74@85009,COG2770@1,COG2770@2,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain gnl|extdb|FAM19036-p1-1.1_002979 1171373.PACID_01580 8.1e-20 102.1 Propionibacteriales Bacteria 2GJPU@201174,4DN80@85009,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase gnl|extdb|FAM19036-p1-1.1_002980 1171373.PACID_01580 1.1e-274 952.6 Propionibacteriales Bacteria 2GJPU@201174,4DN80@85009,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase gnl|extdb|FAM19036-p1-1.1_002983 1171373.PACID_01550 1.4e-296 1025.4 Propionibacteriales Bacteria 2GJPU@201174,4DN80@85009,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase gnl|extdb|FAM19036-p1-1.1_002984 1122998.AUHZ01000006_gene663 4.2e-43 181.0 Propionibacteriales Bacteria 2GJTE@201174,4DNZE@85009,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 gnl|extdb|FAM19036-p1-1.1_002986 1074488.AGBX01000001_gene1305 6.3e-153 547.7 Actinobacteria 2.8.2.22 ko:K01023 ko00000,ko01000 Bacteria 2A5FI@1,2I8X3@201174,30U5H@2 NA|NA|NA S Arylsulfotransferase Ig-like domain gnl|extdb|FAM19036-p1-1.1_002988 1171373.PACID_01520 6.1e-308 1062.8 Actinobacteria ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter gnl|extdb|FAM19036-p1-1.1_002989 1171373.PACID_01510 1.3e-257 895.2 Propionibacteriales hsrA_2 Bacteria 2H4H5@201174,4DWGG@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002990 1171373.PACID_01500 1.1e-228 798.9 Propionibacteriales rtcB 6.5.1.3 ko:K14415 ko00000,ko01000,ko03016 Bacteria 2GIUP@201174,4DPPZ@85009,COG1690@1,COG1690@2 NA|NA|NA S tRNA-splicing ligase RtcB gnl|extdb|FAM19036-p1-1.1_002991 1171373.PACID_01490 1.1e-28 132.1 Bacteria Bacteria COG3657@1,COG3657@2 NA|NA|NA K addiction module killer protein gnl|extdb|FAM19036-p1-1.1_002992 1171373.PACID_01480 1.5e-46 191.8 Actinobacteria Bacteria 2IRAI@201174,COG3636@1,COG3636@2 NA|NA|NA K Addiction module gnl|extdb|FAM19036-p1-1.1_002993 1171373.PACID_01470 7.7e-43 179.5 Actinobacteria ko:K15773 ko00000,ko02048,ko03000 Bacteria 2I3XR@201174,COG1813@1,COG1813@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM19036-p1-1.1_002995 1171373.PACID_01460 6.4e-114 416.8 Propionibacteriales Bacteria 2GJ46@201174,4DPI9@85009,COG2197@1,COG2197@2 NA|NA|NA T Two component transcriptional regulator, LuxR family gnl|extdb|FAM19036-p1-1.1_002997 1171373.PACID_01440 0.0 1473.8 Propionibacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJTZ@201174,4DQ29@85009,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain gnl|extdb|FAM19036-p1-1.1_003000 1171373.PACID_01410 5.4e-68 263.5 Propionibacteriales Bacteria 2EDGM@1,2IQD1@201174,337CU@2,4DW0N@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003001 1171373.PACID_01400 0.0 1128.6 Propionibacteriales fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GT0X@201174,4DPF3@85009,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family gnl|extdb|FAM19036-p1-1.1_003002 1171373.PACID_01390 5.7e-61 240.0 Bacteria Bacteria COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 gnl|extdb|FAM19036-p1-1.1_003004 1122998.AUHZ01000019_gene1677 7.4e-13 79.3 Actinobacteria Bacteria 2B4AE@1,2GY9D@201174,31X1U@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003005 1171373.PACID_01360 3.1e-99 367.9 Bacteria ko:K07693 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko02022 Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator gnl|extdb|FAM19036-p1-1.1_003007 1171373.PACID_01340 1.3e-193 682.2 Bacteria panE1 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria COG1893@1,COG1893@2 NA|NA|NA H 2-dehydropantoate 2-reductase activity gnl|extdb|FAM19036-p1-1.1_003009 1171373.PACID_01320 1.2e-274 951.8 Propionibacteriales iolA 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJI2@201174,4DNVW@85009,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_003010 1171373.PACID_01310 0.0 1632.8 Propionibacteriales Bacteria 2GWK7@201174,4DP6W@85009,COG1652@1,COG1652@2,COG3170@1,COG3170@2 NA|NA|NA NU LysM domain gnl|extdb|FAM19036-p1-1.1_003011 1171373.PACID_01300 1e-80 306.2 Actinobacteria Bacteria 2I5QJ@201174,COG4961@1,COG4961@2 NA|NA|NA U PFAM TadE family protein gnl|extdb|FAM19036-p1-1.1_003014 1171373.PACID_01270 5.8e-150 537.0 Propionibacteriales ko:K12511 ko00000,ko02044 Bacteria 2HZTC@201174,4DRIG@85009,COG2064@1,COG2064@2 NA|NA|NA NU type II secretion system protein gnl|extdb|FAM19036-p1-1.1_003015 1171373.PACID_01260 1e-157 562.8 Propionibacteriales Bacteria 2GN6E@201174,4DNH4@85009,COG4965@1,COG4965@2 NA|NA|NA U overlaps another CDS with the same product name gnl|extdb|FAM19036-p1-1.1_003017 1171373.PACID_01240 4.4e-138 497.3 Propionibacteriales Bacteria 2HT5K@201174,4DSA9@85009,COG0455@1,COG0455@2 NA|NA|NA D bacterial-type flagellum organization gnl|extdb|FAM19036-p1-1.1_003021 1171373.PACID_01190 3.1e-106 391.0 Actinobacteria ko:K07023 ko00000 Bacteria 2INBY@201174,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_003022 1171373.PACID_01180 1.6e-156 558.9 Propionibacteriales murQ 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 2GN0K@201174,4DTQG@85009,COG2103@1,COG2103@2 NA|NA|NA S Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate gnl|extdb|FAM19036-p1-1.1_003023 1122998.AUHZ01000005_gene826 1.3e-77 296.6 Bacteria 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 R01961 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria COG2971@1,COG2971@2 NA|NA|NA G N-acetylglucosamine kinase activity gnl|extdb|FAM19036-p1-1.1_003024 1171373.PACID_01160 2.1e-175 621.7 Actinobacteria Bacteria 2DZN0@1,2IMWK@201174,32VE8@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003026 1171373.PACID_01140 3.1e-122 444.5 Actinobacteria nanE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006050,GO:0006051,GO:0006053,GO:0006054,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016854,GO:0016857,GO:0016999,GO:0017001,GO:0017144,GO:0019262,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046346,GO:0046348,GO:0046395,GO:0047465,GO:0071704,GO:1901135,GO:1901136,GO:1901575 2.7.1.60,5.1.3.9 ko:K01788,ko:K13967 ko00520,ko01100,map00520,map01100 R02087,R02705 RC00002,RC00017,RC00290 ko00000,ko00001,ko01000 iB21_1397.B21_03034,iECBD_1354.ECBD_0524,iECB_1328.ECB_03083,iECD_1391.ECD_03083,iEcHS_1320.EcHS_A3411,iEcolC_1368.EcolC_0483,iSFV_1184.SFV_3248,iSF_1195.SF3259,iSFxv_1172.SFxv_3571,iS_1188.S3476,iUTI89_1310.UTI89_C3653,ic_1306.c3977 Bacteria 2GTWV@201174,COG3010@1,COG3010@2 NA|NA|NA G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) gnl|extdb|FAM19036-p1-1.1_003027 1171373.PACID_01130 1.5e-158 565.5 Propionibacteriales ko:K10202 ko02010,map02010 M00205 ko00000,ko00001,ko00002,ko02000 3.A.1.1.18 Bacteria 2GNQW@201174,4DN23@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_003028 1171373.PACID_01120 1.1e-184 652.5 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GJZD@201174,4DP76@85009,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_003029 1171373.PACID_01110 4.1e-251 873.6 Propionibacteriales ko:K10118,ko:K10200 ko02010,map02010 M00196,M00205 ko00000,ko00001,ko00002,ko02000 3.A.1.1.18,3.A.1.1.28 Bacteria 2GJM5@201174,4DPVB@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_003030 1171373.PACID_01100 6.7e-167 593.2 Propionibacteriales Bacteria 2I8R7@201174,4DRYI@85009,COG4667@1,COG4667@2 NA|NA|NA S Patatin-like phospholipase gnl|extdb|FAM19036-p1-1.1_003031 1171373.PACID_01090 5.6e-200 703.4 Propionibacteriales pat 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJXS@201174,4DNVN@85009,COG0079@1,COG0079@2 NA|NA|NA E May catalyze the transamination reaction in phenylalanine biosynthesis gnl|extdb|FAM19036-p1-1.1_003033 1171373.PACID_01070 0.0 1370.9 Propionibacteriales glnP ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJJ9@201174,4DQBU@85009,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_003034 1171373.PACID_01050 3.4e-233 813.9 Propionibacteriales eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2IA5M@201174,4DWPR@85009,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis gnl|extdb|FAM19036-p1-1.1_003035 1171373.PACID_01040 6.5e-201 706.4 Propionibacteriales lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 2GJV5@201174,4DP41@85009,COG0095@1,COG0095@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family gnl|extdb|FAM19036-p1-1.1_003036 1171373.PACID_01030 1.9e-65 255.0 Actinobacteria ko:K07979 ko00000,ko03000 Bacteria 2IQKP@201174,COG1725@1,COG1725@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_003037 1171373.PACID_01020 4.8e-171 607.1 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GRE8@201174,4DPKX@85009,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_003038 1171373.PACID_01010 2e-116 425.2 Actinobacteria Bacteria 2DN4H@1,2ITCJ@201174,32VGQ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003039 1171373.PACID_01000 2.5e-141 508.1 Actinobacteria Bacteria 2IGW1@201174,COG0561@1,COG0561@2 NA|NA|NA S HAD hydrolase, family IIB gnl|extdb|FAM19036-p1-1.1_003040 1171373.PACID_00990 1.4e-43 181.8 Bacteria 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria COG0010@1,COG0010@2 NA|NA|NA E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines gnl|extdb|FAM19036-p1-1.1_003041 1171373.PACID_00970 1.2e-194 685.6 Actinobacteria gpsA 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJSD@201174,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase gnl|extdb|FAM19036-p1-1.1_003042 1171373.PACID_00960 8.5e-306 1055.4 Actinobacteria 2.7.1.17,2.7.1.5 ko:K00848,ko:K00854 ko00040,ko00051,ko01100,ko01120,map00040,map00051,map01100,map01120 M00014 R01639,R01902,R03014 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNCR@201174,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family gnl|extdb|FAM19036-p1-1.1_003043 1171373.PACID_00930 1.9e-75 288.5 Actinobacteria 2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K03491 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279 R03232,R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1 Bacteria 2H0MP@201174,COG1762@1,COG1762@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 gnl|extdb|FAM19036-p1-1.1_003044 1171373.PACID_00920 1.1e-228 798.9 Actinobacteria ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 Bacteria 2IBG5@201174,COG3775@1,COG3775@2 NA|NA|NA G PTS system Galactitol-specific IIC component gnl|extdb|FAM19036-p1-1.1_003045 1171373.PACID_00910 6.8e-47 193.0 Actinobacteria 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 Bacteria 2H8V1@201174,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit gnl|extdb|FAM19036-p1-1.1_003046 1171373.PACID_00900 2.5e-200 704.5 Actinobacteria 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKBE@201174,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_003047 1171373.PACID_00890 0.0 1209.1 Actinobacteria 2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K03491 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279 R03232,R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1 Bacteria 2HXN0@201174,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA GKT transcriptional antiterminator gnl|extdb|FAM19036-p1-1.1_003048 1171373.PACID_00880 1.1e-115 422.5 Propionibacteriales fucA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 4.1.2.17,4.1.2.19,5.1.3.4 ko:K01628,ko:K01629,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R01785,R02262,R02263,R05850 RC00438,RC00599,RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNI6@201174,4DPWM@85009,COG0235@1,COG0235@2 NA|NA|NA G Class II Aldolase and Adducin N-terminal domain gnl|extdb|FAM19036-p1-1.1_003049 1171373.PACID_00870 0.0 1134.4 Propionibacteriales ko:K12954 ko00000,ko01000 3.A.3 Bacteria 2GIRF@201174,4DPEN@85009,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase gnl|extdb|FAM19036-p1-1.1_003051 1171373.PACID_03410 1.6e-196 691.8 Propionibacteriales Bacteria 2IAHV@201174,4DUEP@85009,COG3335@1,COG3335@2,COG3415@1,COG3415@2 NA|NA|NA L Winged helix-turn helix gnl|extdb|FAM19036-p1-1.1_003054 585530.HMPREF0183_1158 5.7e-165 587.4 Brevibacteriaceae gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4F8EN@85019,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_003055 1171373.PACID_00410 3.4e-227 793.9 Actinobacteria 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 2H8H4@201174,COG0620@1,COG0620@2 NA|NA|NA E Methionine synthase gnl|extdb|FAM19036-p1-1.1_003056 1171373.PACID_00400 0.0 2158.3 Propionibacteriales pyc 2.1.3.1,6.4.1.1 ko:K01958,ko:K17490 ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230 M00173 R00344,R00353 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18410 Bacteria 2H238@201174,4DP0F@85009,COG1038@1,COG1038@2 NA|NA|NA C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second gnl|extdb|FAM19036-p1-1.1_003057 1171373.PACID_00390 4e-173 614.0 Actinobacteria ldh 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GN5S@201174,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family gnl|extdb|FAM19036-p1-1.1_003058 1171373.PACID_00380 0.0 1119.8 Propionibacteriales malS GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 R00214 RC00105 ko00000,ko00001,ko01000 Bacteria 2GJAJ@201174,4DTGZ@85009,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme, NAD binding domain gnl|extdb|FAM19036-p1-1.1_003060 1171373.PACID_00360 0.0 2152.5 Propionibacteriales lacZ 3.2.1.23 ko:K01190,ko:K12111 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GMAT@201174,4DPD7@85009,COG3250@1,COG3250@2 NA|NA|NA G Beta galactosidase small chain gnl|extdb|FAM19036-p1-1.1_003061 1171373.PACID_00350 1.1e-173 615.9 Actinobacteria ldh GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 2GN5S@201174,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family gnl|extdb|FAM19036-p1-1.1_003062 1171373.PACID_00340 6.2e-123 446.8 Propionibacteriales iphP 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 2GK28@201174,4DS4X@85009,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family gnl|extdb|FAM19036-p1-1.1_003063 1171373.PACID_00330 2.3e-216 758.1 Propionibacteriales Bacteria 2H0CW@201174,4DN0M@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_003065 1171373.PACID_00310 7.5e-74 283.1 Propionibacteriales Bacteria 2IIM3@201174,4DRV3@85009,COG0517@1,COG0517@2 NA|NA|NA S Domain in cystathionine beta-synthase and other proteins. gnl|extdb|FAM19036-p1-1.1_003067 1171373.PACID_02680 1e-229 802.4 Actinobacteria Bacteria 2I8Z0@201174,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives gnl|extdb|FAM19036-p1-1.1_003068 1171373.PACID_00290 1.7e-38 164.9 Bacteria Bacteria COG4118@1,COG4118@2 NA|NA|NA D positive regulation of growth gnl|extdb|FAM19036-p1-1.1_003069 1171373.PACID_00280 9.1e-66 256.1 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 ko:K07064 ko00000 Bacteria 2GRA5@201174,4DSHI@85009,COG1848@1,COG1848@2 NA|NA|NA S PIN domain gnl|extdb|FAM19036-p1-1.1_003070 1171373.PACID_00270 6.5e-45 186.4 Bacteria Bacteria COG3620@1,COG3620@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM19036-p1-1.1_003071 558173.CDOO_04990 1.2e-42 179.1 Actinobacteria VY92_07350 Bacteria 2IQAB@201174,COG4683@1,COG4683@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) gnl|extdb|FAM19036-p1-1.1_003074 1171373.PACID_00230 1e-56 225.7 Propionibacteriales ko:K10947 ko00000,ko03000 Bacteria 2IM8U@201174,4DR4Z@85009,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family gnl|extdb|FAM19036-p1-1.1_003075 1171373.PACID_00220 1.9e-68 265.0 Propionibacteriales Bacteria 2IM9H@201174,4DSCW@85009,COG4817@1,COG4817@2 NA|NA|NA S Protein of unknown function (DUF1048) gnl|extdb|FAM19036-p1-1.1_003076 1171373.PACID_00210 6.7e-142 510.0 Propionibacteriales drrA_1 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,4DQ19@85009,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM19036-p1-1.1_003077 1171373.PACID_00200 7.3e-130 469.9 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIVW@201174,4DP1X@85009,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein gnl|extdb|FAM19036-p1-1.1_003078 1171373.PACID_00190 7.8e-64 249.6 Actinobacteria rbsD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702 5.4.99.62 ko:K06726 ko02010,map02010 R08247 RC02247 ko00000,ko00001,ko01000 Bacteria 2IHP8@201174,COG1869@1,COG1869@2 NA|NA|NA G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose gnl|extdb|FAM19036-p1-1.1_003079 1171373.PACID_00180 1.1e-159 569.3 Propionibacteriales rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2I04R@201174,4DV5F@85009,COG0524@1,COG0524@2 NA|NA|NA G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway gnl|extdb|FAM19036-p1-1.1_003080 1171373.PACID_00170 6.9e-162 576.6 Propionibacteriales rbsB ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2I2HU@201174,4DRVR@85009,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein domain gnl|extdb|FAM19036-p1-1.1_003081 1171373.PACID_00160 2.8e-158 564.7 Propionibacteriales rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2GJDW@201174,4DR3X@85009,COG1172@1,COG1172@2 NA|NA|NA G Belongs to the binding-protein-dependent transport system permease family gnl|extdb|FAM19036-p1-1.1_003082 1171373.PACID_00150 4.4e-275 953.4 Propionibacteriales rbsA 3.6.3.17 ko:K10441 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2GJ3F@201174,4DNG0@85009,COG1129@1,COG1129@2 NA|NA|NA G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system gnl|extdb|FAM19036-p1-1.1_003083 1171373.PACID_00140 9.6e-181 639.4 Propionibacteriales rbsR ko:K02529 ko00000,ko03000 Bacteria 2GNVD@201174,4DQZJ@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_003084 1171373.PACID_00130 5.2e-168 597.0 Propionibacteriales ddhD Bacteria 2GKW0@201174,4DTF6@85009,COG0673@1,COG0673@2 NA|NA|NA S Homoserine dehydrogenase, NAD binding domain gnl|extdb|FAM19036-p1-1.1_003086 1171373.PACID_00110 0.0 1742.6 Propionibacteriales gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJ2Q@201174,4DN2Z@85009,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gnl|extdb|FAM19036-p1-1.1_003087 1171373.PACID_00100 0.0 1361.7 Propionibacteriales gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKGP@201174,4DN1A@85009,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gnl|extdb|FAM19036-p1-1.1_003088 1171373.PACID_00090 1.4e-159 568.9 Propionibacteriales gspK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 R01961 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GKBF@201174,4DSI3@85009,COG2971@1,COG2971@2 NA|NA|NA G BadF/BadG/BcrA/BcrD ATPase family gnl|extdb|FAM19036-p1-1.1_003089 1171373.PACID_00080 1.1e-115 422.5 Propionibacteriales Bacteria 2GNQ4@201174,4DR8Q@85009,COG5512@1,COG5512@2 NA|NA|NA S Protein of unknown function (DUF721) gnl|extdb|FAM19036-p1-1.1_003090 1171373.PACID_00070 1.1e-220 772.3 Propionibacteriales recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJCS@201174,4DNK0@85009,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP gnl|extdb|FAM19036-p1-1.1_003091 1171373.PACID_00060 1.4e-130 472.2 Propionibacteriales Bacteria 2GPFD@201174,4DW7A@85009,COG4762@1,COG4762@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_003092 1171373.PACID_00050 1.1e-206 725.7 Propionibacteriales dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJK3@201174,4DN43@85009,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria gnl|extdb|FAM19036-p1-1.1_003093 1171373.PACID_00030 0.0 1543.9 Propionibacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJTZ@201174,4DWZ8@85009,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain gnl|extdb|FAM19036-p1-1.1_003094 1171373.PACID_00020 9.3e-147 526.2 Propionibacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4DNEX@85009,COG1136@1,COG1136@2 NA|NA|NA V COG1136 ABC-type antimicrobial peptide transport system, ATPase component gnl|extdb|FAM19036-p1-1.1_003095 1171373.PACID_00010 1.3e-276 958.4 Propionibacteriales dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2GJKI@201174,4DMZ1@85009,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids gnl|extdb|FAM19036-p1-1.1_003096 1170318.PALO_10535 8.6e-10 68.6 Actinobacteria rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2HBHE@201174,COG0230@1,COG0230@2 NA|NA|NA J Ribosomal protein L34 gnl|extdb|FAM19036-p1-1.1_003097 1171373.PACID_34330 8e-50 203.4 Bacteria rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria COG0594@1,COG0594@2 NA|NA|NA J ribonuclease P activity gnl|extdb|FAM19036-p1-1.1_003099 1171373.PACID_34310 3.2e-179 634.4 Actinobacteria yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2GJBU@201174,COG0706@1,COG0706@2 NA|NA|NA U Membrane protein insertase, YidC Oxa1 family gnl|extdb|FAM19036-p1-1.1_003104 1171373.PACID_34260 1e-148 532.7 Propionibacteriales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GMU7@201174,4DNHI@85009,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ gnl|extdb|FAM19036-p1-1.1_003105 1171373.PACID_34250 1.5e-177 629.0 Propionibacteriales parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2GNRN@201174,4DNPD@85009,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family gnl|extdb|FAM19036-p1-1.1_003106 1171373.PACID_34240 1.6e-82 312.4 Actinobacteria ligD 6.5.1.1 ko:K01971 ko03450,map03450 R00381 RC00005 ko00000,ko00001,ko01000,ko03400 Bacteria 2IKE5@201174,COG1793@1,COG1793@2 NA|NA|NA L dna ligase gnl|extdb|FAM19036-p1-1.1_003107 1171373.PACID_34230 2.1e-58 231.5 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2E65S@1,2IMEQ@201174,330UF@2,4DSE6@85009 NA|NA|NA S Domain of unknown function (DUF3817) gnl|extdb|FAM19036-p1-1.1_003109 1171373.PACID_34210 9.8e-172 609.4 Propionibacteriales ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2GRWM@201174,4DNS4@85009,COG1181@1,COG1181@2 NA|NA|NA M Belongs to the D-alanine--D-alanine ligase family gnl|extdb|FAM19036-p1-1.1_003112 1171373.PACID_34170 1.8e-139 501.9 Propionibacteriales yegW ko:K03710 ko00000,ko03000 Bacteria 2GJZ1@201174,4DQMB@85009,COG2188@1,COG2188@2 NA|NA|NA K UTRA gnl|extdb|FAM19036-p1-1.1_003113 1171373.PACID_34160 3e-284 983.8 Propionibacteriales mmsA 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJI2@201174,4DNVW@85009,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_003115 1171373.PACID_34140 1.4e-189 668.7 Propionibacteriales iolG 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2GJCY@201174,4DT8B@85009,COG0673@1,COG0673@2 NA|NA|NA S Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) gnl|extdb|FAM19036-p1-1.1_003116 1171373.PACID_34130 5.9e-168 596.7 Propionibacteriales iolH ko:K06605 ko00000 Bacteria 2GMU1@201174,4DVPQ@85009,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel gnl|extdb|FAM19036-p1-1.1_003117 1171373.PACID_34120 1.2e-185 655.6 Actinobacteria ko:K02529,ko:K06145 ko00000,ko03000 Bacteria 2GK1X@201174,COG1609@1,COG1609@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_003118 1171373.PACID_34110 1.4e-300 1038.1 Actinobacteria araP ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.26 Bacteria 2I77C@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM19036-p1-1.1_003119 1171373.PACID_34100 6.7e-176 623.2 Bacteria ko:K02529,ko:K06145 ko00000,ko03000 Bacteria COG1609@1,COG1609@2 NA|NA|NA K purine nucleotide biosynthetic process gnl|extdb|FAM19036-p1-1.1_003122 1171373.PACID_34060 3e-164 584.3 Actinobacteria Bacteria 2GNT5@201174,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel gnl|extdb|FAM19036-p1-1.1_003123 1171373.PACID_34050 4.3e-209 733.8 Propionibacteriales Bacteria 2GPVY@201174,4DPR4@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold gnl|extdb|FAM19036-p1-1.1_003124 1171373.PACID_34040 2.9e-170 604.4 Propionibacteriales iolE 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 Bacteria 2GJKJ@201174,4DPUG@85009,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel gnl|extdb|FAM19036-p1-1.1_003125 1171373.PACID_34020 8.2e-158 563.1 Propionibacteriales yeiH Bacteria 2GS6E@201174,4DQTV@85009,COG2855@1,COG2855@2 NA|NA|NA S Conserved hypothetical protein 698 gnl|extdb|FAM19036-p1-1.1_003126 1171373.PACID_34010 4.9e-157 560.5 Actinobacteria Bacteria 2GMES@201174,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_003127 1171373.PACID_34000 6.9e-173 613.2 Actinobacteria lacI4 ko:K02529,ko:K06145 ko00000,ko03000 Bacteria 2IR0K@201174,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_003128 1171373.PACID_33990 2.7e-224 784.3 Propionibacteriales Bacteria 2GK0F@201174,4DPFS@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM19036-p1-1.1_003129 1171373.PACID_33980 2.7e-177 627.9 Propionibacteriales Bacteria 2GK1S@201174,4DNDR@85009,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel gnl|extdb|FAM19036-p1-1.1_003135 1122997.AUDD01000019_gene2285 2.2e-164 585.9 Actinobacteria Bacteria 2GUV6@201174,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_003138 1122997.AUDD01000019_gene2285 5.5e-223 780.8 Actinobacteria Bacteria 2GUV6@201174,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_003139 716541.ECL_00098 1.1e-11 78.2 Enterobacter Bacteria 1N71U@1224,1S1VR@1236,28KRJ@1,2ZA92@2,3X3AJ@547 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003140 1122997.AUDD01000004_gene1273 1.9e-75 289.3 Actinobacteria Bacteria 2IPFM@201174,COG3103@1,COG4991@2 NA|NA|NA T sh3 domain protein gnl|extdb|FAM19036-p1-1.1_003145 105422.BBPM01000044_gene1799 2.7e-30 139.8 Bacteria Bacteria COG3930@1,COG3930@2 NA|NA|NA E Protein conserved in bacteria gnl|extdb|FAM19036-p1-1.1_003146 710111.FraQA3DRAFT_3319 4.5e-26 126.7 Actinobacteria Bacteria 2BWYT@1,2IEA5@201174,32RGY@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003150 404589.Anae109_1667 2e-47 197.2 Deltaproteobacteria Bacteria 1R87S@1224,2WNMW@28221,42R16@68525,COG0476@1,COG0476@2,COG1310@1,COG1310@2 NA|NA|NA H PFAM UBA THIF-type NAD FAD binding protein gnl|extdb|FAM19036-p1-1.1_003155 944560.HMPREF9058_0151 2.5e-11 76.3 Actinobacteria Bacteria 2H4H2@201174,4D3A2@85005,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase gnl|extdb|FAM19036-p1-1.1_003156 435830.HMPREF0045_01187 6.7e-57 228.8 Actinobacteria Bacteria 2H4H2@201174,4D3A2@85005,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase gnl|extdb|FAM19036-p1-1.1_003157 1171373.PACID_33960 2.2e-191 674.9 Propionibacteriales tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMF9@201174,4DN6D@85009,COG0176@1,COG0176@2 NA|NA|NA G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway gnl|extdb|FAM19036-p1-1.1_003158 1171373.PACID_33950 8.7e-114 416.4 Propionibacteriales Bacteria 2I8Y7@201174,4DU0I@85009,COG2197@1,COG2197@2 NA|NA|NA KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain gnl|extdb|FAM19036-p1-1.1_003159 1171373.PACID_33940 0.0 1326.2 Bacteria Bacteria COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_003161 1171373.PACID_33920 6.8e-279 966.1 Propionibacteriales recD2_4 ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 ko00000,ko00001,ko01000,ko02042,ko02048 Bacteria 2GKJW@201174,4DUFE@85009,COG0467@1,COG0467@2,COG1112@1,COG1112@2 NA|NA|NA L Protein of unknown function (DUF4011) gnl|extdb|FAM19036-p1-1.1_003162 1184609.KILIM_155_00010 1.1e-250 872.1 Dermatophilaceae Bacteria 2GJK7@201174,4F7MV@85018,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_003163 1122997.AUDD01000028_gene677 8.7e-56 223.0 Propionibacteriales Bacteria 2GU7G@201174,4DQSY@85009,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases gnl|extdb|FAM19036-p1-1.1_003164 1122997.AUDD01000025_gene1177 3.2e-77 294.3 Propionibacteriales adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2I45A@201174,4DSTH@85009,COG0563@1,COG0563@2 NA|NA|NA F AAA domain gnl|extdb|FAM19036-p1-1.1_003165 1122997.AUDD01000025_gene1178 2.3e-43 181.4 Propionibacteriales ko:K07343 ko00000 Bacteria 2IKKV@201174,4DSB4@85009,COG3070@1,COG3070@2 NA|NA|NA K TfoX N-terminal domain gnl|extdb|FAM19036-p1-1.1_003167 1122997.AUDD01000025_gene1180 4.1e-207 727.2 Actinobacteria megL 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K01761 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GNZH@201174,COG0626@1,COG0626@2 NA|NA|NA E cystathionine gnl|extdb|FAM19036-p1-1.1_003169 1454010.JEOE01000018_gene1184 8.1e-111 407.5 Actinobacteria Bacteria 28IDI@1,2I4VR@201174,2Z8FT@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003170 1122997.AUDD01000025_gene1183 5e-229 800.0 Actinobacteria Bacteria 2HCJ1@201174,COG2124@1,COG2124@2 NA|NA|NA Q cytochrome p450 gnl|extdb|FAM19036-p1-1.1_003171 1122997.AUDD01000025_gene1184 4.6e-70 270.4 Actinobacteria crtYc Bacteria 2IQR4@201174,33310@2,arCOG05416@1 NA|NA|NA S lycopene cyclase gnl|extdb|FAM19036-p1-1.1_003172 1122997.AUDD01000025_gene1185 3.9e-53 213.8 Propionibacteriales crtYd Bacteria 2E9MI@1,2IMX9@201174,333U6@2,4DS9I@85009 NA|NA|NA S lycopene cyclase gnl|extdb|FAM19036-p1-1.1_003173 1122997.AUDD01000025_gene1186 4.8e-299 1033.1 Propionibacteriales crtU ko:K09879 ko00906,map00906 R07541,R07560,R07857,R07858 RC01901,RC01965 ko00000,ko00001 Bacteria 2GITE@201174,4DPDH@85009,COG3349@1,COG3349@2 NA|NA|NA H Flavin containing amine oxidoreductase gnl|extdb|FAM19036-p1-1.1_003174 1122997.AUDD01000025_gene1187 2.1e-81 308.5 Actinobacteria Bacteria 2IIVB@201174,COG1846@1,COG1846@2 NA|NA|NA K marr family gnl|extdb|FAM19036-p1-1.1_003175 1122997.AUDD01000025_gene1188 8.8e-201 706.1 Actinobacteria crtE 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IFAW@201174,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family gnl|extdb|FAM19036-p1-1.1_003176 1122997.AUDD01000025_gene1189 4.5e-153 547.4 Actinobacteria crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 ko:K00801,ko:K02291,ko:K10208 ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130 M00097 R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177 RC00362,RC00796,RC01101,RC02839,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2I4YZ@201174,COG1562@1,COG1562@2 NA|NA|NA I Squalene/phytoene synthase gnl|extdb|FAM19036-p1-1.1_003177 1122997.AUDD01000025_gene1190 0.0 1094.3 Actinobacteria crtI 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 ko:K10027,ko:K20611 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 2GJAV@201174,COG1233@1,COG1233@2 NA|NA|NA Q phytoene gnl|extdb|FAM19036-p1-1.1_003179 1122997.AUDD01000025_gene1192 4.8e-290 1003.0 Propionibacteriales ko:K07071 ko00000 Bacteria 2GJS0@201174,4DQ87@85009,COG1090@1,COG1090@2,COG4276@1,COG4276@2 NA|NA|NA S Domain of unknown function (DUF1731) gnl|extdb|FAM19036-p1-1.1_003182 1122997.AUDD01000025_gene1195 8.3e-187 659.8 Propionibacteriales Bacteria 2HEUW@201174,4DQY3@85009,COG1511@1,COG1511@2 NA|NA|NA S domain protein gnl|extdb|FAM19036-p1-1.1_003183 1122997.AUDD01000025_gene1196 4.6e-200 703.7 Propionibacteriales ko:K06946 ko00000 Bacteria 2IES1@201174,4DQ6P@85009,COG0218@1,COG0218@2,COG3597@1,COG3597@2 NA|NA|NA D Domain of unknown function (DUF697) gnl|extdb|FAM19036-p1-1.1_003185 1122997.AUDD01000025_gene1198 5.9e-94 350.1 Propionibacteriales Bacteria 2GJJZ@201174,4DUFM@85009,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_003186 1122997.AUDD01000025_gene1199 1.1e-27 128.6 Bacteria csbD Bacteria COG3237@1,COG3237@2 NA|NA|NA K CsbD-like gnl|extdb|FAM19036-p1-1.1_003187 1122997.AUDD01000025_gene1200 2e-86 325.1 Actinobacteria hsp20 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2IHVJ@201174,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family gnl|extdb|FAM19036-p1-1.1_003188 1122997.AUDD01000025_gene1201 3.3e-131 474.6 Propionibacteriales Bacteria 2GP09@201174,4DNYY@85009,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain gnl|extdb|FAM19036-p1-1.1_003189 861360.AARI_pI00160 3.7e-07 60.5 Actinobacteria Bacteria 295CU@1,2GZV0@201174,2ZSQS@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003190 1122997.AUDD01000025_gene1203 3e-111 408.3 Actinobacteria Bacteria 2GST6@201174,COG2207@1,COG2207@2 NA|NA|NA K AraC family gnl|extdb|FAM19036-p1-1.1_003191 1122998.AUHZ01000021_gene1765 9.4e-81 306.2 Propionibacteriales ko:K04750 ko00000 Bacteria 2IG41@201174,4DUH9@85009,COG2764@1,COG2764@2 NA|NA|NA S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gnl|extdb|FAM19036-p1-1.1_003192 1171373.PACID_15790 3.1e-234 817.4 Propionibacteriales Bacteria 2GM8F@201174,4DV2N@85009,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain gnl|extdb|FAM19036-p1-1.1_003193 754252.PFREUD_25030 6.8e-232 809.7 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_003194 1171373.PACID_33920 2.3e-261 907.9 Propionibacteriales recD2_4 ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 ko00000,ko00001,ko01000,ko02042,ko02048 Bacteria 2GKJW@201174,4DUFE@85009,COG0467@1,COG0467@2,COG1112@1,COG1112@2 NA|NA|NA L Protein of unknown function (DUF4011) gnl|extdb|FAM19036-p1-1.1_003195 1171373.PACID_33910 5e-75 287.0 Actinobacteria attW GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2IRWN@201174,COG1765@1,COG1765@2 NA|NA|NA O redox protein, regulator of disulfide bond formation gnl|extdb|FAM19036-p1-1.1_003197 1171373.PACID_33890 1.4e-53 215.3 Actinobacteria trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2IQ9T@201174,COG3118@1,COG3118@2 NA|NA|NA O belongs to the thioredoxin family gnl|extdb|FAM19036-p1-1.1_003199 1171373.PACID_33870 5e-105 387.1 Propionibacteriales ko:K07118 ko00000 Bacteria 2GK2P@201174,4DS5Q@85009,COG2910@1,COG2910@2 NA|NA|NA S NmrA-like family gnl|extdb|FAM19036-p1-1.1_003201 1171373.PACID_33850 8.4e-128 463.0 Bacteria trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria COG0492@1,COG0492@2 NA|NA|NA C ferredoxin-NADP+ reductase activity gnl|extdb|FAM19036-p1-1.1_003202 1171373.PACID_33840 5.5e-189 666.8 Propionibacteriales Bacteria 2GJ5Q@201174,4DTZI@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_003206 1171373.PACID_33790 5e-148 530.4 Propionibacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GITV@201174,4DTRP@85009,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_003207 1171373.PACID_33780 0.0 1386.3 Propionibacteriales 3.2.1.99 ko:K06113 ko00000,ko01000 GH43 Bacteria 2GIYA@201174,4DQ0F@85009,COG3507@1,COG3507@2 NA|NA|NA G Glycosyl hydrolases family 43 gnl|extdb|FAM19036-p1-1.1_003208 1170318.PALO_02095 4.1e-18 99.4 Propionibacteriales lppM GO:0002682,GO:0002683,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0044464,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:0080134 Bacteria 2E8DR@1,2I77J@201174,332S7@2,4DVU2@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003209 1171373.PACID_33760 4.4e-231 807.4 Propionibacteriales degP ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJ96@201174,4DNEM@85009,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like peptidase domain gnl|extdb|FAM19036-p1-1.1_003210 1171373.PACID_33750 1.8e-189 668.3 Actinobacteria Bacteria 2II40@201174,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score gnl|extdb|FAM19036-p1-1.1_003211 1171373.PACID_33740 2.3e-173 614.8 Actinobacteria Bacteria 2GMIM@201174,COG2390@1,COG2390@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM19036-p1-1.1_003212 1171373.PACID_33730 1.7e-139 501.9 Propionibacteriales glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 2GKK3@201174,4DPG7@85009,COG0580@1,COG0580@2 NA|NA|NA G Belongs to the MIP aquaporin (TC 1.A.8) family gnl|extdb|FAM19036-p1-1.1_003213 1171373.PACID_33710 6.7e-300 1035.8 Propionibacteriales glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM13@201174,4DNYQ@85009,COG0554@1,COG0554@2 NA|NA|NA C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate gnl|extdb|FAM19036-p1-1.1_003215 1171373.PACID_33690 2.1e-100 371.7 Propionibacteriales sigM GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K03088 ko00000,ko03021 Bacteria 2GJMX@201174,4DQKT@85009,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor gnl|extdb|FAM19036-p1-1.1_003216 1122998.AUHZ01000005_gene834 2e-212 745.7 Actinobacteria Bacteria 2GM4A@201174,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM19036-p1-1.1_003219 1171373.PACID_33650 5e-173 613.6 Propionibacteriales 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 2GIWC@201174,4DQPU@85009,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase gnl|extdb|FAM19036-p1-1.1_003220 1171373.PACID_33640 2.7e-164 584.7 Propionibacteriales yocS ko:K03453,ko:K14347 ko00000,ko02000,ko04147 2.A.28,2.A.93.1 Bacteria 2GMAM@201174,4DQRS@85009,COG0385@1,COG0385@2 NA|NA|NA S SBF-like CPA transporter family (DUF4137) gnl|extdb|FAM19036-p1-1.1_003221 1171373.PACID_33630 3.1e-289 1000.3 Propionibacteriales gabD2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 ko:K00135,ko:K22445 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ95@201174,4DN6M@85009,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family gnl|extdb|FAM19036-p1-1.1_003222 1171373.PACID_33620 1.7e-287 994.6 Propionibacteriales cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2GMT1@201174,4DMZV@85009,COG0617@1,COG0617@2 NA|NA|NA J Probable RNA and SrmB- binding site of polymerase A gnl|extdb|FAM19036-p1-1.1_003224 1171373.PACID_33600 8.1e-136 490.0 Propionibacteriales glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 2GKHX@201174,4DQ1K@85009,COG1929@1,COG1929@2 NA|NA|NA G Glycerate kinase family gnl|extdb|FAM19036-p1-1.1_003227 1171373.PACID_33580 0.0 1075.8 Propionibacteriales pbp4 Bacteria 2GJAM@201174,4DP57@85009,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein dimerisation domain gnl|extdb|FAM19036-p1-1.1_003228 1171373.PACID_33570 3.3e-93 347.8 Actinobacteria ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 2IKSP@201174,COG1230@1,COG1230@2 NA|NA|NA P Cation efflux family gnl|extdb|FAM19036-p1-1.1_003229 1171373.PACID_33560 8.4e-193 679.5 Actinobacteria pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z5856 Bacteria 2GKNA@201174,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family gnl|extdb|FAM19036-p1-1.1_003230 1171373.PACID_33550 2.4e-136 491.5 Propionibacteriales Bacteria 2GJK9@201174,4DTDZ@85009,COG1349@1,COG1349@2 NA|NA|NA K helix_turn_helix, Deoxyribose operon repressor gnl|extdb|FAM19036-p1-1.1_003234 1171373.PACID_33510 3.7e-159 568.2 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GR00@201174,4DTCW@85009,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component gnl|extdb|FAM19036-p1-1.1_003235 1171373.PACID_33500 9.1e-170 602.8 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IA03@201174,4DTC3@85009,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM19036-p1-1.1_003236 1171373.PACID_33490 2.9e-262 910.6 Propionibacteriales pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 2GNYU@201174,4DQ4H@85009,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family gnl|extdb|FAM19036-p1-1.1_003237 1171373.PACID_33480 7.2e-166 589.7 Actinobacteria Bacteria 2I33B@201174,COG1092@1,COG1092@2 NA|NA|NA J Methyltransferase domain gnl|extdb|FAM19036-p1-1.1_003238 1171373.PACID_33470 9.5e-129 466.1 Actinobacteria ko:K21492 ko00000,ko02048 Bacteria 2DMGT@1,2GT9I@201174,32REF@2 NA|NA|NA S Suppressor of fused protein (SUFU) gnl|extdb|FAM19036-p1-1.1_003239 1171373.PACID_33460 0.0 1215.7 Propionibacteriales thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 iYO844.BSU08790 Bacteria 2GJ3Y@201174,4DN8A@85009,COG0422@1,COG0422@2 NA|NA|NA H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction gnl|extdb|FAM19036-p1-1.1_003240 1171373.PACID_33440 1.3e-268 931.8 Propionibacteriales fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKWY@201174,4DNS5@85009,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate gnl|extdb|FAM19036-p1-1.1_003241 1171373.PACID_33420 4.7e-135 487.3 Bacteria apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria COG1477@1,COG1477@2 NA|NA|NA H protein flavinylation gnl|extdb|FAM19036-p1-1.1_003242 1171373.PACID_33410 6.5e-41 172.9 Actinobacteria 1.1.1.3 ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2IKS1@201174,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family gnl|extdb|FAM19036-p1-1.1_003243 1171373.PACID_33400 1.2e-247 862.1 Actinobacteria XK27_08635 ko:K09157 ko00000 Bacteria 2HHMF@201174,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein gnl|extdb|FAM19036-p1-1.1_003246 1171373.PACID_33370 4.2e-144 517.3 Bacteria Bacteria COG2378@1,COG2378@2 NA|NA|NA K regulation of single-species biofilm formation gnl|extdb|FAM19036-p1-1.1_003248 1171373.PACID_33340 1.7e-90 338.6 Actinobacteria gepA Bacteria 2IT99@201174,COG3600@1,COG3600@2 NA|NA|NA S Protein of unknown function (DUF4065) gnl|extdb|FAM19036-p1-1.1_003249 1122997.AUDD01000011_gene2077 4.7e-217 760.4 Actinobacteria 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 2HUEI@201174,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase gnl|extdb|FAM19036-p1-1.1_003250 1171373.PACID_33320 0.0 1090.1 Propionibacteriales nahA 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 2H28J@201174,4DN2G@85009,COG3525@1,COG3525@2 NA|NA|NA G Glycosyl hydrolase family 20, catalytic domain gnl|extdb|FAM19036-p1-1.1_003251 1120954.ATXE01000001_gene2301 1.5e-24 120.6 Actinobacteria Bacteria 2BVX8@1,2GZ2G@201174,30QZQ@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003252 1171373.PACID_26740 2.7e-267 927.5 Propionibacteriales Bacteria 2GU7G@201174,4DQSY@85009,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases gnl|extdb|FAM19036-p1-1.1_003253 1171373.PACID_33280 4e-198 697.2 Propionibacteriales add GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 R01560,R02556 RC00477 ko00000,ko00001,ko01000 Bacteria 2GJ6I@201174,4DNHH@85009,COG1816@1,COG1816@2 NA|NA|NA F Adenosine/AMP deaminase gnl|extdb|FAM19036-p1-1.1_003254 1171373.PACID_33270 3e-245 854.0 Propionibacteriales gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ7E@201174,4DPEX@85009,COG0372@1,COG0372@2 NA|NA|NA C Belongs to the citrate synthase family gnl|extdb|FAM19036-p1-1.1_003255 1171373.PACID_33260 2.4e-174 618.2 Bacteria rlpA ko:K03642,ko:K21688 ko00000 Bacteria COG0797@1,COG0797@2,COG3103@1,COG4991@2 NA|NA|NA T Sh3 type 3 domain protein gnl|extdb|FAM19036-p1-1.1_003257 1171373.PACID_33240 3.3e-92 344.4 Actinobacteria Bacteria 2DQ2A@1,2I1WX@201174,334FV@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003258 1171373.PACID_33230 7.1e-159 566.6 Actinobacteria ko:K07090 ko00000 Bacteria 2GK5W@201174,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM19036-p1-1.1_003260 1171373.PACID_33200 4.5e-137 493.8 Propionibacteriales yedK Bacteria 2GKY8@201174,4DPFJ@85009,COG2135@1,COG2135@2 NA|NA|NA S Belongs to the SOS response-associated peptidase family gnl|extdb|FAM19036-p1-1.1_003264 1171373.PACID_33160 8.1e-171 606.3 Actinobacteria 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Bacteria 2GPA8@201174,COG2267@1,COG2267@2 NA|NA|NA I hydrolase gnl|extdb|FAM19036-p1-1.1_003265 1171373.PACID_33150 9.5e-211 739.2 Propionibacteriales ald GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030312,GO:0036293,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 2GJ6G@201174,4DNSB@85009,COG0686@1,COG0686@2 NA|NA|NA E Belongs to the AlaDH PNT family gnl|extdb|FAM19036-p1-1.1_003268 1171373.PACID_33110 2.1e-268 931.4 Actinobacteria Bacteria 2GM6E@201174,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM19036-p1-1.1_003269 1171373.PACID_33100 0.0 1587.8 Propionibacteriales GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K01990,ko:K21397 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKEU@201174,4DPMV@85009,COG0842@1,COG0842@2,COG1131@1,COG1131@2,COG1716@1,COG1716@2,COG3266@1,COG3266@2 NA|NA|NA V Inner membrane component of T3SS, cytoplasmic domain gnl|extdb|FAM19036-p1-1.1_003271 1171373.PACID_33080 7.7e-70 269.6 Propionibacteriales nirD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0008942,GO:0009061,GO:0009344,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0046857,GO:0055114,GO:0098809 1.7.1.15 ko:K00362,ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_3772 Bacteria 2IQM4@201174,4DS3Y@85009,COG2146@1,COG2146@2 NA|NA|NA P Nitrite reductase NAD(P)H , small subunit gnl|extdb|FAM19036-p1-1.1_003272 1171373.PACID_33070 0.0 1429.8 Propionibacteriales nadE GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 2H2H9@201174,4DNXS@85009,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source gnl|extdb|FAM19036-p1-1.1_003274 1171373.PACID_33040 1.9e-33 147.9 Actinobacteria GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 ko:K07746 ko00000,ko02048 Bacteria 2GS33@201174,COG3609@1,COG3609@2 NA|NA|NA K addiction module antidote protein, CC2985 family gnl|extdb|FAM19036-p1-1.1_003275 1171373.PACID_33030 2.1e-52 211.5 Actinobacteria ko:K07171 ko00000,ko01000,ko02048 Bacteria 2IM6R@201174,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module gnl|extdb|FAM19036-p1-1.1_003276 1171373.PACID_33020 9.4e-175 619.4 Propionibacteriales cscK 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GYHF@201174,4DQSX@85009,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM19036-p1-1.1_003277 1171373.PACID_33010 2.1e-311 1074.3 Actinobacteria cscA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.26,3.2.1.65 ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 GH32 iE2348C_1286.E2348C_2556,iEC55989_1330.EC55989_2656,iECIAI1_1343.ECIAI1_2428 Bacteria 2GJ9T@201174,COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family gnl|extdb|FAM19036-p1-1.1_003279 77635.BISU_0317 4.1e-144 517.7 Actinobacteria Bacteria 2GIS3@201174,COG0604@1,COG0604@2 NA|NA|NA C alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_003281 1171373.PACID_32960 3.1e-172 610.9 Propionibacteriales Bacteria 2GIUS@201174,4DREC@85009,COG2120@1,COG2120@2 NA|NA|NA S GlcNAc-PI de-N-acetylase gnl|extdb|FAM19036-p1-1.1_003284 1171373.PACID_32930 2.4e-181 641.3 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJY9@201174,4DREQ@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM19036-p1-1.1_003287 1171373.PACID_32900 1.3e-228 798.9 Propionibacteriales Bacteria 2GK9G@201174,4DTFD@85009,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_003288 1171373.PACID_32890 1.4e-84 318.9 Propionibacteriales ybaK GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K03976 ko00000,ko01000,ko03016 Bacteria 2IHS8@201174,4DV7E@85009,COG2606@1,COG2606@2 NA|NA|NA S Aminoacyl-tRNA editing domain gnl|extdb|FAM19036-p1-1.1_003293 1171373.PACID_32830 7.6e-231 806.2 Propionibacteriales dinF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2GJE3@201174,4DPMZ@85009,COG0534@1,COG0534@2 NA|NA|NA V MatE gnl|extdb|FAM19036-p1-1.1_003295 1170318.PALO_01425 4.8e-238 830.1 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM19036-p1-1.1_003296 1349820.M707_00790 2.3e-10 72.0 Actinobacteria Bacteria 2E66C@1,2IR8K@201174,330V0@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003297 1463926.JOCA01000006_gene3524 1.1e-44 188.3 Actinobacteria Bacteria 2GK1D@201174,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM YD repeat protein gnl|extdb|FAM19036-p1-1.1_003298 1101188.KI912157_gene211 8.6e-25 120.6 Bacteria Bacteria COG1413@1,COG1413@2 NA|NA|NA C deoxyhypusine monooxygenase activity gnl|extdb|FAM19036-p1-1.1_003299 1101188.KI912157_gene212 7e-15 87.0 Bacteria Bacteria COG3209@1,COG3209@2 NA|NA|NA M self proteolysis gnl|extdb|FAM19036-p1-1.1_003300 452652.KSE_13070 5.8e-33 148.7 Kitasatospora Bacteria 2GK1D@201174,2M2HZ@2063,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM YD repeat protein gnl|extdb|FAM19036-p1-1.1_003302 1122997.AUDD01000014_gene1444 1.4e-18 100.5 Bacteria Bacteria COG3209@1,COG3209@2 NA|NA|NA M self proteolysis gnl|extdb|FAM19036-p1-1.1_003305 1122998.AUHZ01000033_gene127 1.6e-194 685.3 Propionibacteriales ko:K07494 ko00000 Bacteria 2GJQI@201174,4DUBM@85009,COG3335@1,COG3335@2,COG3415@1,COG3415@2 NA|NA|NA L DDE superfamily endonuclease gnl|extdb|FAM19036-p1-1.1_003307 1171373.PACID_32800 0.0 1229.9 Propionibacteriales sbcC Bacteria 2HU66@201174,4DN58@85009,COG0419@1,COG0419@2 NA|NA|NA L AAA domain gnl|extdb|FAM19036-p1-1.1_003308 1171373.PACID_32790 1e-207 729.2 Propionibacteriales sbcD ko:K03547 ko00000,ko03400 Bacteria 2HZ52@201174,4DN03@85009,COG0420@1,COG0420@2 NA|NA|NA L Calcineurin-like phosphoesterase gnl|extdb|FAM19036-p1-1.1_003309 1171373.PACID_32770 9.3e-95 352.8 Propionibacteriales yceI Bacteria 2GJUB@201174,4DQQD@85009,COG2353@1,COG2353@2 NA|NA|NA S Belongs to the UPF0312 family gnl|extdb|FAM19036-p1-1.1_003310 1171373.PACID_32760 1.4e-83 315.5 Propionibacteriales marR3 Bacteria 2GP6A@201174,4DQZP@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM19036-p1-1.1_003311 1171373.PACID_32750 2e-248 864.8 Propionibacteriales gabP ko:K03293,ko:K11735,ko:K16237 ko00000,ko02000 2.A.3.1,2.A.3.1.12,2.A.3.1.4,2.A.3.1.5 Bacteria 2GJ0X@201174,4DTIR@85009,COG1113@1,COG1113@2 NA|NA|NA E COG1113 Gamma-aminobutyrate permease and related permeases gnl|extdb|FAM19036-p1-1.1_003312 1171373.PACID_32740 1.9e-278 964.5 Actinobacteria clcB ko:K03281 ko00000 2.A.49 Bacteria 2GPPN@201174,COG0038@1,COG0038@2 NA|NA|NA P Chloride channel gnl|extdb|FAM19036-p1-1.1_003313 1171373.PACID_32720 1.8e-87 328.6 Propionibacteriales Bacteria 2I0ED@201174,4DWEC@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM19036-p1-1.1_003314 1171373.PACID_32730 1.6e-174 618.6 Propionibacteriales 1.1.1.26,1.1.1.399,1.1.1.95 ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020 R00717,R01388,R01513 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2I2IC@201174,4DWPG@85009,COG1052@1,COG1052@2 NA|NA|NA CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain gnl|extdb|FAM19036-p1-1.1_003315 1171373.PACID_32710 0.0 1099.7 Actinobacteria glpA GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 iSDY_1059.SDY_2436 Bacteria 2GJKN@201174,COG0578@1,COG0578@2 NA|NA|NA C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family gnl|extdb|FAM19036-p1-1.1_003316 1171373.PACID_32700 1.1e-248 865.5 Actinobacteria glpB GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009061,GO:0009987,GO:0010181,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046168,GO:0046434,GO:0048037,GO:0050662,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575 1.1.5.3 ko:K00112 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 iB21_1397.B21_02127,iEC042_1314.EC042_2485,iECBD_1354.ECBD_1418,iECB_1328.ECB_02168,iECD_1391.ECD_02168,iECUMN_1333.ECUMN_2582,iEcHS_1320.EcHS_A2383,iUMNK88_1353.UMNK88_2792 Bacteria 2GMNS@201174,COG3075@1,COG3075@2 NA|NA|NA E Glycerol-3-phosphate dehydrogenase gnl|extdb|FAM19036-p1-1.1_003317 1171373.PACID_32690 4.3e-252 876.7 Actinobacteria glpC GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 ko:K00113 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2H9RN@201174,COG0247@1,COG0247@2 NA|NA|NA C Glycerol-3-phosphate dehydrogenase gnl|extdb|FAM19036-p1-1.1_003318 1171373.PACID_32680 6.8e-188 663.3 Bacteria 2.7.13.3 ko:K20263 ko02020,ko02024,map02020,map02024 M00818 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_003321 1147128.BAST_0126 5.6e-12 76.6 Bifidobacteriales XK27_10205 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2HZFW@201174,4D0AZ@85004,COG4652@1,COG4652@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003322 1171373.PACID_32620 3.3e-246 857.4 Bacteria XK27_10205 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria COG4652@1,COG4652@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003323 1171373.PACID_02680 1e-229 802.4 Actinobacteria Bacteria 2I8Z0@201174,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives gnl|extdb|FAM19036-p1-1.1_003325 1171373.PACID_32590 0.0 1079.3 Actinobacteria Bacteria 2DUV1@1,2H212@201174,33SFC@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003326 1171373.PACID_32580 3.8e-125 454.1 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GNQJ@201174,4DQM7@85009,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities gnl|extdb|FAM19036-p1-1.1_003327 1171373.PACID_32570 7.5e-244 849.4 Actinobacteria Bacteria 2GJBC@201174,COG5650@1,COG5650@2 NA|NA|NA S phosphatidylinositol metabolic process gnl|extdb|FAM19036-p1-1.1_003328 1171373.PACID_32560 6.2e-114 416.8 Bacteria Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator gnl|extdb|FAM19036-p1-1.1_003329 1171373.PACID_32550 1.6e-194 685.3 Bacteria 2.7.13.3 ko:K20263 ko02020,ko02024,map02020,map02024 M00818 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_003331 1171373.PACID_32520 2.5e-248 864.4 Actinobacteria glcD 1.1.2.4,1.1.3.15 ko:K00102,ko:K00104,ko:K08167 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 M00713,M00714 R00197,R00475 RC00042,RC00044 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3 Bacteria 2GJ2T@201174,COG0277@1,COG0277@2 NA|NA|NA C PFAM FAD linked oxidase domain protein gnl|extdb|FAM19036-p1-1.1_000030 1171373.PACID_32210 3e-107 394.4 Propionibacteriales idi GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0033554,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0050896,GO:0051716,GO:0071704,GO:0090407,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_4179,iECIAI1_1343.ECIAI1_3008,iECO103_1326.ECO103_3464,iECSP_1301.ECSP_3858,iECs_1301.ECs3761,iEcE24377_1341.EcE24377A_3215,iG2583_1286.G2583_3542,iSFV_1184.SFV_2937,iSF_1195.SF2875,iSFxv_1172.SFxv_3153,iSSON_1240.SSON_3042,iS_1188.S3074,iZ_1308.Z4227 Bacteria 2GM26@201174,4DUSY@85009,COG1443@1,COG1443@2 NA|NA|NA I Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) gnl|extdb|FAM19036-p1-1.1_000032 1171373.PACID_32190 9.9e-234 815.8 Propionibacteriales 2.7.13.3 ko:K02484,ko:K07653,ko:K07654 ko02020,map02020 M00460,M00461 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GM17@201174,4DP7S@85009,COG0642@1,COG2205@2,COG5002@1,COG5002@2 NA|NA|NA T PhoQ Sensor gnl|extdb|FAM19036-p1-1.1_000038 1171373.PACID_32130 6.6e-136 490.0 Propionibacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJNJ@201174,4DU5S@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000047 1171373.PACID_32040 8.7e-198 696.0 Propionibacteriales serA Bacteria 2GP09@201174,4DRRR@85009,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain gnl|extdb|FAM19036-p1-1.1_000052 1171373.PACID_31980 1.1e-233 815.5 Actinobacteria msmE7 ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2IAYI@201174,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM19036-p1-1.1_000059 1171373.PACID_31900 1.3e-149 535.8 Propionibacteriales ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 2GMTH@201174,4DU5W@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000066 1171373.PACID_31810 5.1e-178 630.2 Actinobacteria pseT 6.5.1.3 ko:K14680 ko00000,ko01000 Bacteria 2I9VQ@201174,COG4639@1,COG4639@2 NA|NA|NA S AAA domain gnl|extdb|FAM19036-p1-1.1_000077 1171373.PACID_31710 0.0 1481.8 Actinobacteria norZ 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 Bacteria 2I6ZN@201174,COG3256@1,COG3256@2 NA|NA|NA P nitric oxide reductase gnl|extdb|FAM19036-p1-1.1_000080 1171373.PACID_31670 5e-96 357.1 Propionibacteriales Bacteria 2GPDB@201174,4DSSW@85009,COG3797@1,COG3797@2 NA|NA|NA S Protein of unknown function (DUF1697) gnl|extdb|FAM19036-p1-1.1_000081 1171373.PACID_31660 1.5e-308 1064.7 Propionibacteriales proP ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,4DPQY@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM19036-p1-1.1_000087 1171373.PACID_31510 1.6e-48 199.1 Actinobacteria Bacteria 2GTTI@201174,COG3976@1,COG3976@2 NA|NA|NA S FMN-binding domain protein gnl|extdb|FAM19036-p1-1.1_000088 1171373.PACID_31500 2.2e-227 794.7 Propionibacteriales Bacteria 2GKWX@201174,4DWGM@85009,COG4097@1,COG4097@2 NA|NA|NA P ferric reductase gnl|extdb|FAM19036-p1-1.1_000093 1171373.PACID_31460 7.4e-116 423.7 Actinobacteria mrr ko:K07448 ko00000,ko02048 Bacteria 2GP9K@201174,COG1715@1,COG1715@2 NA|NA|NA L Restriction endonuclease gnl|extdb|FAM19036-p1-1.1_000111 1171373.PACID_31380 3.9e-148 530.8 Actinobacteria ehuB ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GN71@201174,COG0834@1,COG0834@2 NA|NA|NA ET Ectoine hydroxyectoine ABC transporter solute-binding protein gnl|extdb|FAM19036-p1-1.1_000116 1171373.PACID_31340 4.5e-119 434.1 Propionibacteriales 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKP7@201174,4DTZZ@85009,COG3473@1,COG3473@2 NA|NA|NA Q Maleate cis-trans isomerase gnl|extdb|FAM19036-p1-1.1_000134 1171373.PACID_31140 1.4e-231 808.5 Propionibacteriales pqqE ko:K22227 ko00000 Bacteria 2GNSY@201174,4DNSX@85009,COG0535@1,COG0535@2 NA|NA|NA C Elongator protein 3, MiaB family, Radical SAM gnl|extdb|FAM19036-p1-1.1_000137 1171373.PACID_31110 3e-184 651.0 Propionibacteriales pdhB GO:0003674,GO:0005488,GO:0005515,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05355,iYO844.BSU14590 Bacteria 2GKFE@201174,4DNN8@85009,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, pyrimidine binding domain gnl|extdb|FAM19036-p1-1.1_000140 1171373.PACID_31080 1.7e-210 738.4 Propionibacteriales alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 2GM2Y@201174,4DNHM@85009,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids gnl|extdb|FAM19036-p1-1.1_000147 1171373.PACID_31010 7e-248 862.8 Actinobacteria Bacteria 2IA73@201174,COG1085@1,COG1085@2 NA|NA|NA C uridylyltransferase gnl|extdb|FAM19036-p1-1.1_000163 1171373.PACID_30840 4.7e-311 1072.8 Propionibacteriales sglT ko:K03307 ko00000 2.A.21 Bacteria 2GKPW@201174,4DNA9@85009,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family gnl|extdb|FAM19036-p1-1.1_000164 1171373.PACID_30820 1.8e-226 791.6 Propionibacteriales galK 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXI@201174,4DQ3A@85009,COG0153@1,COG0153@2 NA|NA|NA G Belongs to the GHMP kinase family gnl|extdb|FAM19036-p1-1.1_000166 1171373.PACID_30800 1.8e-233 815.1 Propionibacteriales Bacteria 2GM55@201174,4DPV3@85009,COG1316@1,COG1316@2 NA|NA|NA K cell envelope-related transcriptional attenuator gnl|extdb|FAM19036-p1-1.1_000175 1171373.PACID_30700 2.5e-216 758.1 Propionibacteriales ko:K08166 ko00000,ko02000 2.A.1.3.10 Bacteria 2H4H5@201174,4DWWI@85009,COG0477@1,COG2814@2 NA|NA|NA P Major Facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000180 1171373.PACID_30630 3.9e-75 287.3 Actinobacteria tadA 3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01485,ko:K01563,ko:K04075,ko:K11991 ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2IM3Z@201174,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) gnl|extdb|FAM19036-p1-1.1_000179 1292373.H640_01580 7.9e-57 227.3 Actinobacteria Bacteria 2BM8T@1,2IG06@201174,32FSI@2 NA|NA|NA S tRNA adenosine gnl|extdb|FAM19036-p1-1.1_000181 1171373.PACID_30620 2.3e-240 837.8 Actinobacteria wzx Bacteria 2I8P2@201174,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein gnl|extdb|FAM19036-p1-1.1_000184 1171373.PACID_30540 8.3e-162 576.2 Actinobacteria Bacteria 2IHAY@201174,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease gnl|extdb|FAM19036-p1-1.1_000194 1171373.PACID_30430 2.1e-207 728.0 Propionibacteriales aecD 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 2GJFQ@201174,4DQQR@85009,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase class I and II gnl|extdb|FAM19036-p1-1.1_000210 1171373.PACID_30260 9.2e-200 702.6 Actinobacteria gatD 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC7@201174,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_000221 1122997.AUDD01000026_gene1221 3.4e-119 434.9 Propionibacteriales yhfT 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2I908@201174,4DV3A@85009,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme gnl|extdb|FAM19036-p1-1.1_000224 1105031.HMPREF1141_1988 6.2e-96 357.5 Clostridiaceae MA20_34185 ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UYCY@1239,249RH@186801,36G8Z@31979,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000236 1171373.PACID_29820 0.0 1457.2 Propionibacteriales Bacteria 2GJKC@201174,4DP0I@85009,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor gnl|extdb|FAM19036-p1-1.1_000237 1171373.PACID_29810 0.0 1204.5 Propionibacteriales kup ko:K03549 ko00000,ko02000 2.A.72 Bacteria 2GMPQ@201174,4DU3B@85009,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell gnl|extdb|FAM19036-p1-1.1_000240 1171373.PACID_29780 9.8e-186 656.0 Propionibacteriales yrpG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 Bacteria 2GMNA@201174,4DUH4@85009,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM19036-p1-1.1_000244 1171373.PACID_29730 1.6e-82 312.0 Propionibacteriales furA 1.11.1.6 ko:K03781,ko:K22297 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2IFBR@201174,4DQM6@85009,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family gnl|extdb|FAM19036-p1-1.1_000264 1171373.PACID_29520 1.2e-31 142.1 Actinobacteria MA20_40075 Bacteria 2GQR5@201174,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein gnl|extdb|FAM19036-p1-1.1_000267 1171373.PACID_29490 3.6e-243 847.0 Propionibacteriales pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK03@201174,4DNTP@85009,COG0596@1,COG0596@2 NA|NA|NA S Alpha beta hydrolase gnl|extdb|FAM19036-p1-1.1_000282 1171373.PACID_29340 1.4e-203 715.3 Propionibacteriales ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2H4BW@201174,4DNHC@85009,COG4608@1,COG4608@2 NA|NA|NA E Belongs to the ABC transporter superfamily gnl|extdb|FAM19036-p1-1.1_000297 1171373.PACID_29180 3.5e-171 607.4 Propionibacteriales ykuE ko:K07098 ko00000 Bacteria 2GJHT@201174,4DNBM@85009,COG1408@1,COG1408@2 NA|NA|NA S Calcineurin-like phosphoesterase gnl|extdb|FAM19036-p1-1.1_000303 1171373.PACID_29120 8.8e-124 449.5 Propionibacteriales nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ01@201174,4DNJN@85009,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate gnl|extdb|FAM19036-p1-1.1_000305 1171373.PACID_29100 1.1e-95 355.9 Propionibacteriales Bacteria 2GKG9@201174,4DQJF@85009,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain gnl|extdb|FAM19036-p1-1.1_000310 1171373.PACID_29050 1.1e-104 386.3 Bacteria ko:K12510 ko00000,ko02044 Bacteria COG4965@1,COG4965@2 NA|NA|NA U Type ii secretion system gnl|extdb|FAM19036-p1-1.1_000315 1171373.PACID_29000 1.5e-136 492.3 Actinobacteria pabC 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GN5Z@201174,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase gnl|extdb|FAM19036-p1-1.1_000323 1171373.PACID_28920 0.0 1518.8 Propionibacteriales yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 ko:K06877 ko00000 Bacteria 2GJJ6@201174,4DNQG@85009,COG1061@1,COG1061@2,COG1205@1,COG1205@2 NA|NA|NA L Domain of unknown function (DUF1998) gnl|extdb|FAM19036-p1-1.1_000329 1171373.PACID_28850 1.5e-209 735.3 Propionibacteriales holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ8C@201174,4DNVR@85009,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III gnl|extdb|FAM19036-p1-1.1_000331 1171373.PACID_28830 1.1e-166 592.4 Actinobacteria tpl Bacteria 2HYDT@201174,COG1774@1,COG1774@2 NA|NA|NA S PFAM PSP1 domain protein gnl|extdb|FAM19036-p1-1.1_000332 1171373.PACID_28820 1.2e-293 1015.0 Propionibacteriales slpD Bacteria 2GJYS@201174,4DNG9@85009,COG0596@1,COG0596@2 NA|NA|NA S TAP-like protein gnl|extdb|FAM19036-p1-1.1_000341 1171373.PACID_28730 0.0 1081.2 Propionibacteriales guaA1 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GN1H@201174,4DP8S@85009,COG0518@1,COG0518@2,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM19036-p1-1.1_000342 1171373.PACID_28720 1.1e-200 705.7 Propionibacteriales 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 2GN82@201174,4DNSK@85009,COG2355@1,COG2355@2 NA|NA|NA E Membrane dipeptidase (Peptidase family M19) gnl|extdb|FAM19036-p1-1.1_000361 1171373.PACID_28530 3.2e-97 360.9 Propionibacteriales ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 iNJ661.Rv3628 Bacteria 2GM7F@201174,4DQYI@85009,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions gnl|extdb|FAM19036-p1-1.1_000366 1171373.PACID_28480 2.2e-108 398.3 Propionibacteriales folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iIT341.HP0928,iNJ661.Rv3609c Bacteria 2GP2P@201174,4DN6R@85009,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase gnl|extdb|FAM19036-p1-1.1_000375 1292373.H640_01116 4e-161 575.1 Propionibacteriales nth 2.1.1.37,4.2.99.18 ko:K00558,ko:K07457,ko:K10773 ko00270,ko01100,ko03410,ko05206,map00270,map01100,map03410,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJR6@201174,4DVPX@85009,COG0177@1,COG0177@2,COG0270@1,COG0270@2 NA|NA|NA H C-5 cytosine-specific DNA methylase gnl|extdb|FAM19036-p1-1.1_000397 1171373.PACID_28220 1.7e-159 568.5 Propionibacteriales mutY 2.1.1.37,2.1.3.15,6.4.1.2 ko:K00558,ko:K01962,ko:K01963,ko:K03575 ko00061,ko00270,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03410,ko05206,map00061,map00270,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map03410,map05206 M00035,M00082,M00376 R00742,R04386,R04858 RC00003,RC00040,RC00253,RC00332,RC00367 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJD9@201174,4DP1C@85009,COG1194@1,COG1194@2 NA|NA|NA L FES gnl|extdb|FAM19036-p1-1.1_000399 1171373.PACID_28200 9.5e-175 619.4 Propionibacteriales hemB GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 iECABU_c1320.ECABU_c04500,iEcSMS35_1347.EcSMS35_0398,iJN746.PP_2913,ic_1306.c0477 Bacteria 2GJJ0@201174,4DNVG@85009,COG0113@1,COG0113@2 NA|NA|NA H Belongs to the ALAD family gnl|extdb|FAM19036-p1-1.1_000404 1171373.PACID_28140 2.2e-252 877.9 Propionibacteriales hemA GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 ko:K02407,ko:K02492 ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000,ko02035 iSB619.SA_RS08420 Bacteria 2GJRA@201174,4DPDT@85009,COG0373@1,COG0373@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) gnl|extdb|FAM19036-p1-1.1_000412 1171373.PACID_28060 5.5e-175 620.2 Propionibacteriales ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 R10507 RC00083 ko00000,ko00001,ko01000 Bacteria 2GJTK@201174,4DP4A@85009,COG0506@1,COG0506@2 NA|NA|NA E Proline dehydrogenase gnl|extdb|FAM19036-p1-1.1_000413 1171373.PACID_28050 9e-136 489.6 Propionibacteriales ko:K07052 ko00000 Bacteria 2GK11@201174,4DR9W@85009,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM19036-p1-1.1_000417 1170318.PALO_08960 1.5e-27 129.0 Actinobacteria Bacteria 2GZVY@201174,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin-like domain (DUF836) gnl|extdb|FAM19036-p1-1.1_000421 1171373.PACID_27970 6.4e-99 366.7 Propionibacteriales resA ko:K02199 ko00000,ko03110 Bacteria 2GP7J@201174,4DRHT@85009,COG0526@1,COG0526@2 NA|NA|NA CO Redoxin gnl|extdb|FAM19036-p1-1.1_000422 1171373.PACID_27960 8.9e-122 443.0 Propionibacteriales ccdA ko:K06196 ko00000,ko02000 5.A.1.2 Bacteria 2GJW3@201174,4DPTU@85009,COG0785@1,COG0785@2 NA|NA|NA O cytochrome c biogenesis protein, transmembrane region gnl|extdb|FAM19036-p1-1.1_000428 1171373.PACID_27900 1.2e-310 1071.6 Propionibacteriales glpD 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJKN@201174,4DNPC@85009,COG0578@1,COG0578@2 NA|NA|NA C FAD dependent oxidoreductase gnl|extdb|FAM19036-p1-1.1_000431 1171373.PACID_27870 1.3e-287 995.0 Propionibacteriales ilvA GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95,4.3.1.19 ko:K00058,ko:K01754,ko:K04767 ko00260,ko00290,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00290,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020,M00570 R00220,R00996,R01513 RC00031,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_2699 Bacteria 2GJAG@201174,4DP7V@85009,COG1171@1,COG1171@2,COG4747@1,COG4747@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA gnl|extdb|FAM19036-p1-1.1_000441 1171373.PACID_27770 1.3e-163 582.4 Actinobacteria znuA ko:K02077,ko:K09815,ko:K11707 ko02010,map02010 M00242,M00244,M00319 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2IEKU@201174,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family gnl|extdb|FAM19036-p1-1.1_000442 1171373.PACID_27760 8.4e-131 473.0 Actinobacteria ko:K02074,ko:K06994,ko:K09820 M00243,M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 2GN95@201174,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter gnl|extdb|FAM19036-p1-1.1_000448 1171373.PACID_27690 2.3e-40 171.0 Propionibacteriales rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ4I@201174,4DSIQ@85009,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 gnl|extdb|FAM19036-p1-1.1_000470 478801.Ksed_20340 1.2e-263 915.2 Actinobacteria repB ko:K02031,ko:K02032,ko:K15269,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 2.A.7.3.3,3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2IBZ4@201174,COG0444@1,COG0444@2 NA|NA|NA EP Plasmid replication protein gnl|extdb|FAM19036-p1-1.1_000491 1171373.PACID_27370 2.9e-251 874.0 Propionibacteriales purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMP4@201174,4DNMU@85009,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP gnl|extdb|FAM19036-p1-1.1_000494 1171373.PACID_27330 5e-243 846.7 Propionibacteriales purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.3.1,6.3.4.13,6.3.5.3 ko:K01945,ko:K01952,ko:K11788,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208,R04463,R04591 RC00010,RC00064,RC00090,RC00162,RC00166,RC01100,RC01160 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729,iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 2I2F5@201174,4DN4W@85009,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family gnl|extdb|FAM19036-p1-1.1_000502 1171373.PACID_27250 0.0 1674.4 Propionibacteriales pepN_1 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ4@201174,4DNEA@85009,COG0308@1,COG0308@2 NA|NA|NA E ERAP1-like C-terminal domain gnl|extdb|FAM19036-p1-1.1_000510 1171373.PACID_27170 0.0 1510.7 Actinobacteria norZ 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 Bacteria 2I6ZN@201174,COG3256@1,COG3256@2 NA|NA|NA P nitric oxide reductase gnl|extdb|FAM19036-p1-1.1_000541 1122238.AULR01000003_gene1343 1.3e-31 142.5 Bacteria Bacteria COG4983@1,COG4983@2 NA|NA|NA L Phage plasmid primase, P4 family domain protein gnl|extdb|FAM19036-p1-1.1_000553 288705.RSal33209_0067 1.3e-36 159.1 Micrococcaceae Bacteria 1WCGW@1268,2IQH9@201174,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor gnl|extdb|FAM19036-p1-1.1_000563 1171373.PACID_26790 8.4e-122 443.0 Propionibacteriales Bacteria 2I9MN@201174,4DUED@85009,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain gnl|extdb|FAM19036-p1-1.1_000573 1122998.AUHZ01000002_gene2052 3.5e-200 704.1 Propionibacteriales Bacteria 2GKCU@201174,4DNNU@85009,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase gnl|extdb|FAM19036-p1-1.1_000579 1171373.PACID_26610 3.1e-153 547.7 Actinobacteria fieF Bacteria 2GJ8Q@201174,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family gnl|extdb|FAM19036-p1-1.1_000581 1171373.PACID_26590 4e-139 500.7 Bacteria GalU 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis gnl|extdb|FAM19036-p1-1.1_000586 1171373.PACID_26540 7.7e-233 812.8 Propionibacteriales pimH Bacteria 2I2EY@201174,4DNW0@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_000593 1171373.PACID_26470 2e-278 964.5 Propionibacteriales Bacteria 2DBR7@1,2INCX@201174,2ZAIR@2,4DRA5@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000597 1171373.PACID_26430 9.4e-222 775.8 Propionibacteriales menF 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKE8@201174,4DPGF@85009,COG1169@1,COG1169@2 NA|NA|NA HQ Isochorismate synthase gnl|extdb|FAM19036-p1-1.1_000601 1171373.PACID_26390 8.2e-127 459.9 Propionibacteriales nuoC GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GIRH@201174,4DPNJ@85009,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM19036-p1-1.1_000610 1171373.PACID_26300 0.0 1209.5 Propionibacteriales nuoL 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GIT4@201174,4DP65@85009,COG1009@1,COG1009@2 NA|NA|NA CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus gnl|extdb|FAM19036-p1-1.1_000617 1171373.PACID_26230 1.7e-143 515.4 Propionibacteriales citE 3.1.2.30,4.1.3.25,4.1.3.34 ko:K01644,ko:K14451,ko:K18292 ko00630,ko00660,ko01100,ko01120,ko01200,ko02020,map00630,map00660,map01100,map01120,map01200,map02020 M00373 R00237,R00362,R10612 RC00004,RC00014,RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK5J@201174,4DPA5@85009,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family gnl|extdb|FAM19036-p1-1.1_000620 1171373.PACID_26200 9.3e-176 622.9 Propionibacteriales ytfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 iAPECO1_1312.APECO1_2162,iECH74115_1262.ECH74115_5749,iECOK1_1307.ECOK1_4745,iECSF_1327.ECSF_4119,iLF82_1304.LF82_3716,iUTI89_1310.UTI89_C4834,ic_1306.c5327 Bacteria 2HB45@201174,4DPP2@85009,COG1172@1,COG1172@2 NA|NA|NA G Branched-chain amino acid transport system / permease component gnl|extdb|FAM19036-p1-1.1_000623 1171373.PACID_26160 9.9e-216 755.7 Propionibacteriales korB 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GMI5@201174,4DQ3H@85009,COG1013@1,COG1013@2 NA|NA|NA C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain gnl|extdb|FAM19036-p1-1.1_000628 1171373.PACID_26110 7e-286 989.2 Propionibacteriales ko:K14337,ko:K14339 ko00000,ko01000,ko01003 Bacteria 2DBIT@1,2GN9J@201174,2Z9GU@2,4DTW6@85009 NA|NA|NA S Carotene biosynthesis associated membrane protein gnl|extdb|FAM19036-p1-1.1_000629 1171373.PACID_26100 1.8e-167 595.1 Actinobacteria hibch 3.1.2.4,4.2.1.17 ko:K01692,ko:K05605 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00013,M00032,M00087 R03026,R03045,R03158,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05064,R05595,R06411,R06412,R06942,R08093 RC00004,RC00014,RC00137,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMET@201174,COG1024@1,COG1024@2 NA|NA|NA I enoyl-CoA hydratase gnl|extdb|FAM19036-p1-1.1_000671 1171373.PACID_25660 0.0 1299.3 Propionibacteriales 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMAT@201174,4DPVI@85009,COG3250@1,COG3250@2 NA|NA|NA G Glycosyl hydrolases family 2, TIM barrel domain gnl|extdb|FAM19036-p1-1.1_000690 1171373.PACID_25460 8.5e-307 1058.9 Propionibacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ9N@201174,4DUB4@85009,COG0747@1,COG0747@2 NA|NA|NA E COG0747 ABC-type dipeptide transport system, periplasmic component gnl|extdb|FAM19036-p1-1.1_000714 1171373.PACID_25210 2.5e-132 478.0 Propionibacteriales trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 2GJ8R@201174,4DNDX@85009,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA gnl|extdb|FAM19036-p1-1.1_000730 1171373.PACID_25050 5.1e-159 567.0 Propionibacteriales ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 2IKV2@201174,4DPK9@85009,COG0802@1,COG0802@2 NA|NA|NA K Threonylcarbamoyl adenosine biosynthesis protein TsaE gnl|extdb|FAM19036-p1-1.1_000755 1171373.PACID_24790 7.5e-227 792.7 Propionibacteriales cls-1 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_3078 Bacteria 2GM0P@201174,4DP3Y@85009,COG1502@1,COG1502@2 NA|NA|NA I Phospholipase D. Active site motifs. gnl|extdb|FAM19036-p1-1.1_000756 1171373.PACID_24780 3.6e-85 321.2 Propionibacteriales metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GY65@201174,4DQ48@85009,COG2011@1,COG2011@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_000773 1171373.PACID_24590 1.1e-40 172.2 Actinobacteria Bacteria 2DRQP@1,2GYKP@201174,33CNM@2 NA|NA|NA S Protein of unknown function (DUF3017) gnl|extdb|FAM19036-p1-1.1_000780 1171373.PACID_24510 2.5e-236 824.3 Propionibacteriales ko:K07028 ko00000 Bacteria 2IB1T@201174,4DUJY@85009,COG2334@1,COG2334@2 NA|NA|NA S Phosphotransferase enzyme family gnl|extdb|FAM19036-p1-1.1_000794 1171373.PACID_24370 6.1e-213 746.5 Actinobacteria rnfC ko:K03615 ko00000 Bacteria 2GU2T@201174,COG4656@1,COG4656@2 NA|NA|NA C Part of a membrane complex involved in electron transport gnl|extdb|FAM19036-p1-1.1_000797 1171373.PACID_24320 0.0 1120.5 Propionibacteriales 6.2.1.3,6.2.1.31 ko:K00666,ko:K01897,ko:K16876 ko00061,ko00071,ko00365,ko01100,ko01120,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00365,map01100,map01120,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R02986 RC00004,RC00014,RC00174 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIUC@201174,4DWKQ@85009,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme gnl|extdb|FAM19036-p1-1.1_000810 1171373.PACID_24190 1.4e-32 144.8 Actinobacteria Bacteria 2DFKT@1,2GT3J@201174,2ZS8K@2 NA|NA|NA S Acyl-CoA carboxylase epsilon subunit gnl|extdb|FAM19036-p1-1.1_000812 1171373.PACID_24170 3.8e-139 500.7 Propionibacteriales birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03524 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GN8Q@201174,4DQT5@85009,COG0340@1,COG0340@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family gnl|extdb|FAM19036-p1-1.1_000817 1171373.PACID_24120 1.2e-169 602.4 Propionibacteriales lytR2 Bacteria 2GJJJ@201174,4DPY2@85009,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain gnl|extdb|FAM19036-p1-1.1_000834 1171373.PACID_23950 1.6e-151 542.0 Bacteria Bacteria COG1714@1,COG1714@2 NA|NA|NA S RDD family gnl|extdb|FAM19036-p1-1.1_000841 1171373.PACID_23880 0.0 1279.2 Actinobacteria feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 2GTV2@201174,COG0370@1,COG0370@2 NA|NA|NA P Ferrous iron transport protein B gnl|extdb|FAM19036-p1-1.1_000844 1171373.PACID_23850 4.2e-133 480.7 Propionibacteriales rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 ko:K00989,ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJFI@201174,4DN7G@85009,COG0689@1,COG0689@2 NA|NA|NA J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates gnl|extdb|FAM19036-p1-1.1_000847 1171373.PACID_23820 1.3e-87 328.9 Propionibacteriales folA 1.5.1.3 ko:K00287,ko:K18589 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 2IM1S@201174,4DRUF@85009,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis gnl|extdb|FAM19036-p1-1.1_000853 1171373.PACID_23760 8e-48 196.1 Propionibacteriales groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IHRC@201174,4DR8F@85009,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter gnl|extdb|FAM19036-p1-1.1_000854 1171373.PACID_23750 1.9e-135 488.4 Propionibacteriales guaA_2 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GKS1@201174,4DU8K@85009,COG0518@1,COG0518@2 NA|NA|NA F Glutamine amidotransferase class-I gnl|extdb|FAM19036-p1-1.1_000859 1171373.PACID_23700 9.8e-98 362.8 Actinobacteria imuA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 ko:K14160 ko00000,ko03400 Bacteria 2IRRW@201174,COG4544@1,COG4544@2 NA|NA|NA S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division gnl|extdb|FAM19036-p1-1.1_000887 1171373.PACID_23310 6.2e-107 393.7 Propionibacteriales tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IFH0@201174,4DQTX@85009,COG2818@1,COG2818@2 NA|NA|NA L Methyladenine glycosylase gnl|extdb|FAM19036-p1-1.1_000891 1171373.PACID_23270 1.9e-112 411.8 Propionibacteriales orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GJR7@201174,4DPKU@85009,COG1949@1,COG1949@2 NA|NA|NA L 3'-to-5' exoribonuclease specific for small oligoribonucleotides gnl|extdb|FAM19036-p1-1.1_000901 1171373.PACID_23170 2.3e-54 218.0 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM19036-p1-1.1_000907 1171373.PACID_23110 4e-98 364.0 Propionibacteriales Bacteria 2I2EX@201174,4DQVF@85009,COG3917@1,COG3917@2 NA|NA|NA Q DSBA oxidoreductase gnl|extdb|FAM19036-p1-1.1_000915 1171373.PACID_23030 0.0 2124.4 Propionibacteriales lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 2GKE0@201174,4DNHS@85009,COG1190@1,COG1190@2,COG2898@1,COG2898@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family gnl|extdb|FAM19036-p1-1.1_000932 1171373.PACID_22670 3.6e-309 1066.6 Propionibacteriales zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 2GISI@201174,4DNXH@85009,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone gnl|extdb|FAM19036-p1-1.1_000934 1171373.PACID_22650 1.2e-155 555.8 Propionibacteriales ctaA ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 Bacteria 2GJQX@201174,4DQ6X@85009,COG1612@1,COG1612@2 NA|NA|NA O cytochrome oxidase assembly gnl|extdb|FAM19036-p1-1.1_000936 1171373.PACID_22630 6.4e-128 463.4 Propionibacteriales drrA_2 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJBF@201174,4DNVC@85009,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM19036-p1-1.1_000943 1171373.PACID_22510 2.4e-275 954.1 Propionibacteriales sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 2GKCZ@201174,4DN7B@85009,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) gnl|extdb|FAM19036-p1-1.1_000944 1171373.PACID_22500 3.4e-205 720.7 Actinobacteria sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 2GJNV@201174,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD gnl|extdb|FAM19036-p1-1.1_000949 1171373.PACID_22450 1.2e-61 242.3 Propionibacteriales yitW ko:K02612,ko:K03593 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001,ko03029,ko03036 Bacteria 2IKUH@201174,4DR2I@85009,COG2151@1,COG2151@2 NA|NA|NA S Pfam:DUF59 gnl|extdb|FAM19036-p1-1.1_000955 1171373.PACID_22380 4.9e-69 266.9 Propionibacteriales elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 2IFAM@201174,4DS8N@85009,COG2153@1,COG2153@2 NA|NA|NA F Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_000958 1171373.PACID_22350 8.9e-119 433.0 Actinobacteria rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 R07233 RC00003 ko00000,ko01000,ko03009 Bacteria 2HCAN@201174,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase gnl|extdb|FAM19036-p1-1.1_000961 1171373.PACID_22320 9.3e-47 192.6 Propionibacteriales Bacteria 2EGIC@1,2I19N@201174,33AAH@2,4DSK8@85009 NA|NA|NA S Protein of unknown function (DUF3099) gnl|extdb|FAM19036-p1-1.1_000966 1032480.MLP_14780 2.1e-20 106.3 Propionibacteriales Bacteria 2BK9Y@1,2GMZH@201174,32EQ4@2,4DR19@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_000996 1238186.AOCN01000004_gene20 1.2e-08 65.5 Microbacteriaceae Bacteria 2I8FY@201174,4FRJK@85023,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain gnl|extdb|FAM19036-p1-1.1_001004 1171373.PACID_21880 1.3e-134 485.7 Propionibacteriales yfcA ko:K07090 ko00000 Bacteria 2GMNQ@201174,4DPHQ@85009,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM19036-p1-1.1_001011 1171373.PACID_21810 4.7e-68 263.8 Propionibacteriales rbfA ko:K02834 ko00000,ko03009 Bacteria 2IKXP@201174,4DR3E@85009,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA gnl|extdb|FAM19036-p1-1.1_001015 1171373.PACID_21770 6e-170 603.6 Actinobacteria srlE GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0090563 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 Bacteria 2IBIS@201174,COG3732@1,COG3732@2 NA|NA|NA G Sorbitol phosphotransferase enzyme II N-terminus gnl|extdb|FAM19036-p1-1.1_001046 1171373.PACID_21470 6.8e-104 383.3 Actinobacteria MA20_09515 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 2IQYV@201174,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein gnl|extdb|FAM19036-p1-1.1_001055 1171373.PACID_21340 1.2e-137 495.7 Propionibacteriales trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GJ1G@201174,4DNVI@85009,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family gnl|extdb|FAM19036-p1-1.1_001056 1171373.PACID_21330 5.6e-122 443.7 Propionibacteriales sdhC ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 28HIR@1,2GN2S@201174,2Z7U4@2,4DQJ4@85009 NA|NA|NA S succinate dehydrogenase gnl|extdb|FAM19036-p1-1.1_001061 1171373.PACID_21280 2.7e-114 417.9 Propionibacteriales rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFN@201174,4DPWD@85009,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids gnl|extdb|FAM19036-p1-1.1_001101 1171373.PACID_20860 3.4e-177 627.5 Propionibacteriales nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2GKM2@201174,4DPDG@85009,COG0061@1,COG0061@2 NA|NA|NA G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP gnl|extdb|FAM19036-p1-1.1_001109 1171373.PACID_20780 4.3e-154 550.8 Propionibacteriales fkbB 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2GJK2@201174,4DS0W@85009,COG0545@1,COG0545@2 NA|NA|NA O FKBP-type peptidyl-prolyl cis-trans isomerase gnl|extdb|FAM19036-p1-1.1_001114 1171373.PACID_20730 6.1e-19 99.8 Bacteria tatA ko:K03116 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria COG1826@1,COG1826@2 NA|NA|NA U protein secretion gnl|extdb|FAM19036-p1-1.1_001115 1171373.PACID_20720 5.2e-139 500.4 Propionibacteriales tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2GJK8@201174,4DQFM@85009,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides gnl|extdb|FAM19036-p1-1.1_001116 1171373.PACID_20710 2.7e-174 617.8 Propionibacteriales dagK GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GK3P@201174,4DPPK@85009,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain gnl|extdb|FAM19036-p1-1.1_001138 1171373.PACID_20480 1e-209 735.7 Propionibacteriales ddl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008716,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464,GO:0050896 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Bacteria 2GITC@201174,4DT59@85009,COG1181@1,COG1181@2 NA|NA|NA M Belongs to the D-alanine--D-alanine ligase family gnl|extdb|FAM19036-p1-1.1_001141 1171373.PACID_20440 0.0 1474.1 Propionibacteriales ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2GK3T@201174,4DN14@85009,COG1674@1,COG1674@2 NA|NA|NA D Ftsk_gamma gnl|extdb|FAM19036-p1-1.1_001150 1171373.PACID_20350 8.1e-191 672.9 Propionibacteriales argC GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQK@201174,4DNZ7@85009,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde gnl|extdb|FAM19036-p1-1.1_001162 1171373.PACID_20240 1e-84 319.3 Propionibacteriales ctsW 3.6.4.12 ko:K02242,ko:K03654 ko03018,map03018 M00429 ko00000,ko00001,ko00002,ko01000,ko02044,ko03400 Bacteria 2I9PA@201174,4DRM7@85009,COG1040@1,COG1040@2 NA|NA|NA S phosphoribosyltransferase gnl|extdb|FAM19036-p1-1.1_001164 1171373.PACID_20220 5.7e-209 733.4 Propionibacteriales ycaQ ko:K09927 ko00000 Bacteria 2GJM7@201174,4DN5U@85009,COG3214@1,COG3214@2 NA|NA|NA S Winged helix DNA-binding domain gnl|extdb|FAM19036-p1-1.1_001165 1171373.PACID_20210 0.0 1771.9 Propionibacteriales secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GIRT@201174,4DPEU@85009,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane gnl|extdb|FAM19036-p1-1.1_001169 1171373.PACID_20170 9.9e-160 569.3 Propionibacteriales PPA1328 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 2GNAP@201174,4DP8Q@85009,COG0613@1,COG0613@2 NA|NA|NA S DNA polymerase alpha chain like domain gnl|extdb|FAM19036-p1-1.1_001173 1122611.KB903974_gene2890 4.5e-07 61.6 Streptosporangiales GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0071771 1.16.3.1,4.1.99.5 ko:K03594,ko:K14331 ko00860,map00860 R00078 RC02758 ko00000,ko00001,ko01000 Bacteria 2I2E1@201174,4ER04@85012,COG1633@1,COG1633@2 NA|NA|NA S tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like gnl|extdb|FAM19036-p1-1.1_001189 1171373.PACID_20000 2.7e-189 667.9 Propionibacteriales lon ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 2GJDD@201174,4DQEN@85009,COG3480@1,COG3480@2 NA|NA|NA T Domain present in PSD-95, Dlg, and ZO-1/2. gnl|extdb|FAM19036-p1-1.1_001214 1171373.PACID_19760 0.0 2344.7 Propionibacteriales sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 2GIU6@201174,4DN7Q@85009,COG0508@1,COG0508@2,COG0567@1,COG0567@2 NA|NA|NA C 2-oxoglutarate dehydrogenase gnl|extdb|FAM19036-p1-1.1_001224 1171373.PACID_19650 2.1e-154 551.6 Propionibacteriales prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2GMH1@201174,4DP23@85009,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif gnl|extdb|FAM19036-p1-1.1_001223 1171373.PACID_19660 4.3e-181 640.6 Propionibacteriales prfA GO:0008150,GO:0040007 ko:K02835,ko:K15034 ko00000,ko03012 Bacteria 2GJWG@201174,4DP4Q@85009,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA gnl|extdb|FAM19036-p1-1.1_001248 1171373.PACID_19410 5e-125 453.8 Propionibacteriales atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 2H3PR@201174,4DPUV@85009,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane gnl|extdb|FAM19036-p1-1.1_001250 1171373.PACID_19390 5.3e-61 240.7 Propionibacteriales atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GJS4@201174,4DQDT@85009,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) gnl|extdb|FAM19036-p1-1.1_001260 1171373.PACID_19290 1.4e-42 178.3 Propionibacteriales Bacteria 2E3EP@1,2GQST@201174,32YDP@2,4DS23@85009 NA|NA|NA S ATP- GTP-binding protein gnl|extdb|FAM19036-p1-1.1_001262 1171373.PACID_19270 1.5e-36 160.6 Propionibacteriales ko:K02107 ko00190,map00190 M00159 ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 Bacteria 2I5QR@201174,4DQKZ@85009,COG3064@1,COG3064@2 NA|NA|NA M DivIVA protein gnl|extdb|FAM19036-p1-1.1_001267 1171373.PACID_19210 6.7e-141 506.9 Propionibacteriales trxA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2GJ7B@201174,4DN3B@85009,COG3118@1,COG3118@2 NA|NA|NA O Tetratricopeptide repeat gnl|extdb|FAM19036-p1-1.1_001269 1171373.PACID_19190 0.0 1676.4 Propionibacteriales 2.4.1.64 ko:K05342 ko00500,ko01100,map00500,map01100 R02727 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 2GKEV@201174,4DNX8@85009,COG1554@1,COG1554@2 NA|NA|NA G Glycosyl hydrolase family 65 central catalytic domain gnl|extdb|FAM19036-p1-1.1_001272 1171373.PACID_19150 2.7e-228 797.7 Propionibacteriales treS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 ko:K00700,ko:K05343,ko:K16146 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01557,R02108,R02110,R02112,R09945,R11262 RC00002,RC00078,RC01816 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 2GKAP@201174,4DNWM@85009,COG3281@1,COG3281@2 NA|NA|NA G protein probably involved in trehalose biosynthesis gnl|extdb|FAM19036-p1-1.1_001273 1171373.PACID_19140 0.0 1367.8 Propionibacteriales glgE 2.4.1.18,2.4.99.16 ko:K00700,ko:K07214,ko:K16147 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110,R09994 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 2GJKR@201174,4DMZD@85009,COG0296@1,COG0296@2,COG0366@1,COG0366@2 NA|NA|NA G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB gnl|extdb|FAM19036-p1-1.1_001283 1171373.PACID_19020 3.7e-90 337.4 Propionibacteriales Bacteria 2GS5H@201174,4DSAP@85009,COG1238@1,COG1238@2 NA|NA|NA I metal cluster binding gnl|extdb|FAM19036-p1-1.1_001296 1171373.PACID_18240 1e-240 839.0 Propionibacteriales trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM7Z@201174,4DN45@85009,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine gnl|extdb|FAM19036-p1-1.1_001303 1171373.PACID_18170 1.1e-156 559.3 Propionibacteriales ko:K10242 ko02010,map02010 M00206 ko00000,ko00001,ko00002,ko02000 3.A.1.1.23 Bacteria 2GK1V@201174,4DQHC@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001327 1171373.PACID_17930 2.3e-130 471.5 Propionibacteriales ycbL 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 2GJU0@201174,4DNMS@85009,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily gnl|extdb|FAM19036-p1-1.1_001329 1171373.PACID_17910 0.0 2854.7 Propionibacteriales hgdC Bacteria 2I1VH@201174,4DVSF@85009,COG1924@1,COG1924@2,COG3580@1,COG3580@2,COG3581@1,COG3581@2 NA|NA|NA I CoA enzyme activase uncharacterised domain (DUF2229) gnl|extdb|FAM19036-p1-1.1_001349 1171373.PACID_17710 1.3e-70 272.3 Propionibacteriales nusB GO:0008150,GO:0040007 ko:K03625 ko00000,ko03009,ko03021 Bacteria 2IM3D@201174,4DRMH@85009,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons gnl|extdb|FAM19036-p1-1.1_001366 1171373.PACID_17550 1.3e-153 548.9 Propionibacteriales ko:K07184 ko00000 Bacteria 2GK10@201174,4DNMH@85009,COG1938@1,COG1938@2 NA|NA|NA S PAC2 family gnl|extdb|FAM19036-p1-1.1_001369 1171373.PACID_17520 3.4e-55 220.7 Propionibacteriales Bacteria 2E6D0@1,2GQP8@201174,3310N@2,4DS3S@85009 NA|NA|NA S Protein of unknown function (DUF3054) gnl|extdb|FAM19036-p1-1.1_001382 1396858.Q666_00160 7.9e-41 173.3 Gammaproteobacteria hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1RHRY@1224,1S2N0@1236,COG0732@1,COG0732@2 NA|NA|NA L restriction gnl|extdb|FAM19036-p1-1.1_001414 446462.Amir_4340 4.2e-97 361.7 Pseudonocardiales ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 2GP5W@201174,4E8GK@85010,COG2807@1,COG2807@2 NA|NA|NA P Major Facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_001422 1171373.PACID_16970 2.7e-76 291.2 Propionibacteriales lrp_3 ko:K03719 ko00000,ko03000,ko03036 Bacteria 2HA3J@201174,4DWPS@85009,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type gnl|extdb|FAM19036-p1-1.1_001423 1171373.PACID_16960 8.2e-274 949.1 Propionibacteriales lnt GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K03820 ko00000,ko01000 GT2 iNJ661.Rv2051c Bacteria 2GJ9F@201174,4DP6S@85009,COG0815@1,COG0815@2 NA|NA|NA M Transfers the fatty acyl group on membrane lipoproteins gnl|extdb|FAM19036-p1-1.1_001431 1171373.PACID_16860 4.4e-31 139.8 Bacteria ybdD Bacteria COG2879@1,COG2879@2 NA|NA|NA S small protein gnl|extdb|FAM19036-p1-1.1_001442 1171373.PACID_16740 0.0 2173.7 Actinobacteria 4.1.1.38 ko:K20370 ko00620,ko01100,map00620,map01100 R00346 RC02741 ko00000,ko00001,ko01000 Bacteria 28HY3@1,2H218@201174,2Z83I@2 NA|NA|NA S phosphoenolpyruvate carboxykinase (diphosphate) activity gnl|extdb|FAM19036-p1-1.1_001443 1171373.PACID_16730 9.9e-88 329.7 Propionibacteriales yigZ 2.1.1.45,3.4.13.9 ko:K00560,ko:K01271 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GMM4@201174,4DQWQ@85009,COG1739@1,COG1739@2 NA|NA|NA S Uncharacterized protein family UPF0029 gnl|extdb|FAM19036-p1-1.1_001446 1171373.PACID_16700 1.7e-104 385.6 Propionibacteriales mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8GZ@201174,4DWBI@85009,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively gnl|extdb|FAM19036-p1-1.1_001469 1171373.PACID_16460 5.4e-173 613.6 Bacteria epsG ko:K00786 ko00000,ko01000 Bacteria COG1215@1,COG1215@2 NA|NA|NA M transferase activity, transferring glycosyl groups gnl|extdb|FAM19036-p1-1.1_001478 1171373.PACID_16360 6.1e-105 386.7 Propionibacteriales Bacteria 2AIF4@1,2GK8R@201174,318WM@2,4DQE6@85009 NA|NA|NA S Protein of unknown function (DUF3000) gnl|extdb|FAM19036-p1-1.1_001488 1171373.PACID_16260 3e-112 411.4 Propionibacteriales Bacteria 28J4D@1,2GJYC@201174,2Z90C@2,4DRF5@85009 NA|NA|NA S Protein of unknown function (DUF3710) gnl|extdb|FAM19036-p1-1.1_001501 1171373.PACID_16120 5.3e-226 790.0 Propionibacteriales MA20_25070 ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 2GJCW@201174,4DNKE@85009,COG2270@1,COG2270@2 NA|NA|NA S Vacuole effluxer Atg22 like gnl|extdb|FAM19036-p1-1.1_001515 1171373.PACID_15970 0.0 1280.0 Propionibacteriales dinG GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0070035,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GKT8@201174,4DN8C@85009,COG1199@1,COG1199@2 NA|NA|NA KL HELICc2 gnl|extdb|FAM19036-p1-1.1_001522 1171373.PACID_15270 2.7e-229 801.2 Propionibacteriales rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2I9DW@201174,4DQ4C@85009,COG1418@1,COG1418@2 NA|NA|NA M Endoribonuclease that initiates mRNA decay gnl|extdb|FAM19036-p1-1.1_001523 1051006.HMPREF1162_0375 4.8e-44 184.1 Propionibacteriales recX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03565 ko00000,ko03400 Bacteria 2GMRF@201174,4DR2K@85009,COG2137@1,COG2137@2 NA|NA|NA S Modulates RecA activity gnl|extdb|FAM19036-p1-1.1_001526 1171373.PACID_15230 3.6e-129 467.6 Propionibacteriales agaR ko:K02081,ko:K02444 ko00000,ko03000 Bacteria 2GJK9@201174,4DWSJ@85009,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain gnl|extdb|FAM19036-p1-1.1_001530 1171373.PACID_15190 4.8e-268 929.9 Propionibacteriales rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 2GKRI@201174,4DNHY@85009,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 gnl|extdb|FAM19036-p1-1.1_001542 1171373.PACID_15070 9.7e-247 859.0 Propionibacteriales pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0T@201174,4DMZJ@85009,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily gnl|extdb|FAM19036-p1-1.1_001543 1171373.PACID_15060 2.7e-91 341.3 Propionibacteriales pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 2GJNP@201174,4DQ8W@85009,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant gnl|extdb|FAM19036-p1-1.1_001546 1171373.PACID_15030 1.7e-75 288.5 Propionibacteriales Bacteria 2B57P@1,2I89I@201174,32TPU@2,4DQZ6@85009 NA|NA|NA S Protein of unknown function (DUF3052) gnl|extdb|FAM19036-p1-1.1_001548 1171373.PACID_15010 1.6e-216 758.4 Propionibacteriales Bacteria 2GN0S@201174,4DNAE@85009,COG2508@1,COG2508@2 NA|NA|NA QT PucR C-terminal helix-turn-helix domain gnl|extdb|FAM19036-p1-1.1_001558 1171373.PACID_14910 1.8e-173 615.1 Actinobacteria ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2GNKP@201174,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A gnl|extdb|FAM19036-p1-1.1_001560 1171373.PACID_14890 3.6e-188 664.1 Propionibacteriales ko:K03924 ko00000,ko01000 Bacteria 2GK07@201174,4DNJJ@85009,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) gnl|extdb|FAM19036-p1-1.1_001561 1171373.PACID_14880 3e-111 408.3 Propionibacteriales Bacteria 2BYTB@1,2IIS4@201174,33S2I@2,4DSUF@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_001572 1171373.PACID_18630 3.4e-95 354.4 Propionibacteriales lysE GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 ko:K06895 ko00000,ko02000 2.A.75.1 Bacteria 2IHQ2@201174,4DQJE@85009,COG1279@1,COG1279@2 NA|NA|NA S LysE type translocator gnl|extdb|FAM19036-p1-1.1_001575 1171373.PACID_18600 1.4e-259 901.7 Propionibacteriales pdxR ko:K00375 ko00000,ko03000 Bacteria 2GJ5P@201174,4DPW7@85009,COG1167@1,COG1167@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor gnl|extdb|FAM19036-p1-1.1_001589 1171373.PACID_18470 6.1e-232 809.7 Propionibacteriales dus Bacteria 2GJ8I@201174,4DNZA@85009,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines gnl|extdb|FAM19036-p1-1.1_001592 1171373.PACID_18410 0.0 1333.9 Propionibacteriales sdhA 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ45@201174,4DN0E@85009,COG1053@1,COG1053@2 NA|NA|NA C succinate dehydrogenase gnl|extdb|FAM19036-p1-1.1_001598 1171373.PACID_18350 1.2e-155 555.8 Propionibacteriales nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2IP@201174,4DNUU@85009,COG0157@1,COG0157@2 NA|NA|NA H Belongs to the NadC ModD family gnl|extdb|FAM19036-p1-1.1_001619 1171373.PACID_14360 5.7e-256 889.8 Propionibacteriales Bacteria 2GJVW@201174,4DN27@85009,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family gnl|extdb|FAM19036-p1-1.1_001627 1171373.PACID_14280 3.9e-221 773.9 Propionibacteriales Bacteria 2I8QF@201174,4DPN5@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_001631 1171373.PACID_14240 2.6e-42 177.6 Bacteria Bacteria COG2002@1,COG2002@2 NA|NA|NA K toxin-antitoxin pair type II binding gnl|extdb|FAM19036-p1-1.1_001654 1171373.PACID_14020 1.1e-167 595.9 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GJ0R@201174,4DNVK@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001663 1171373.PACID_13930 1.2e-103 382.5 Propionibacteriales SEN0012 Bacteria 2HCGE@201174,4DR5A@85009,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family gnl|extdb|FAM19036-p1-1.1_001665 1171373.PACID_13910 8.6e-218 762.7 Propionibacteriales menE GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN9C@201174,4DP67@85009,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme gnl|extdb|FAM19036-p1-1.1_001668 1171373.PACID_13880 1.3e-171 609.0 Propionibacteriales menC GO:0008150,GO:0040007 4.2.1.113,5.1.1.20,5.1.1.3 ko:K01776,ko:K02549,ko:K19802 ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110 M00116 R00260,R04031,R10938 RC00302,RC01053,RC03309 ko00000,ko00001,ko00002,ko01000,ko01011 iNJ661.Rv0553,iSB619.SA_RS09080 Bacteria 2GJJR@201174,4DNKN@85009,COG4948@1,COG4948@2 NA|NA|NA M Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) gnl|extdb|FAM19036-p1-1.1_001674 1171373.PACID_13830 0.0 1163.3 Propionibacteriales ams 2.4.1.4,3.2.1.1,5.4.99.16 ko:K05341,ko:K05343 ko00500,ko01100,map00500,map01100 R01557,R01823,R02108,R02112,R11262 RC00028,RC01816 ko00000,ko00001,ko01000 GH13 Bacteria 2GKT9@201174,4DNNS@85009,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain gnl|extdb|FAM19036-p1-1.1_001676 1171373.PACID_13810 2.4e-170 604.7 Propionibacteriales holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GNMZ@201174,4DN5C@85009,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III, delta subunit gnl|extdb|FAM19036-p1-1.1_001679 1171373.PACID_13780 5.8e-96 357.5 Propionibacteriales comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2IQDC@201174,4DRFZ@85009,COG1555@1,COG1555@2 NA|NA|NA L Helix-hairpin-helix motif gnl|extdb|FAM19036-p1-1.1_001697 1171373.PACID_13590 2.2e-99 368.2 Actinobacteria Bacteria 2GM10@201174,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system gnl|extdb|FAM19036-p1-1.1_001724 1171373.PACID_13400 1.3e-128 465.7 Propionibacteriales gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.73,3.1.3.85 ko:K02226,ko:K22306 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJYU@201174,4DRFR@85009,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family gnl|extdb|FAM19036-p1-1.1_001726 1171373.PACID_13380 2e-123 448.4 Propionibacteriales nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2GMFZ@201174,4DNX3@85009,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) gnl|extdb|FAM19036-p1-1.1_001734 1171373.PACID_13290 1.6e-134 485.3 Propionibacteriales Bacteria 2GIS7@201174,4DQ75@85009,COG5011@1,COG5011@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2344) gnl|extdb|FAM19036-p1-1.1_001741 1171373.PACID_13220 1.9e-31 141.4 Propionibacteriales secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GR31@201174,4DS3V@85009,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase SecG subunit gnl|extdb|FAM19036-p1-1.1_001746 1171373.PACID_13170 6.5e-187 659.8 Propionibacteriales ybhK Bacteria 2GJBW@201174,4DNYU@85009,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions gnl|extdb|FAM19036-p1-1.1_001753 1171373.PACID_13100 1.9e-124 451.8 Propionibacteriales 5.2.1.4 ko:K16163 ko00350,ko01100,ko01120,map00350,map01100,map01120 R03868 RC00867 ko00000,ko00001,ko01000 Bacteria 2C7TJ@1,2GP9X@201174,31RF6@2,4DS45@85009 NA|NA|NA S Mycothiol maleylpyruvate isomerase N-terminal domain gnl|extdb|FAM19036-p1-1.1_001757 1171373.PACID_13050 1.4e-99 369.0 Propionibacteriales coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN96@201174,4DQNK@85009,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A gnl|extdb|FAM19036-p1-1.1_001769 1171373.PACID_12940 4.8e-86 323.9 Propionibacteriales lspA GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKRX@201174,4DRH4@85009,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins gnl|extdb|FAM19036-p1-1.1_001779 1171373.PACID_12840 2.6e-203 714.5 Actinobacteria ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 2GKXP@201174,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family gnl|extdb|FAM19036-p1-1.1_001784 1171373.PACID_12790 0.0 1136.3 Propionibacteriales ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2GKHH@201174,4DNVU@85009,COG0768@1,COG0768@2 NA|NA|NA M Cell division protein FtsI penicillin-binding protein gnl|extdb|FAM19036-p1-1.1_001788 1171373.PACID_12750 6.9e-167 593.2 Propionibacteriales ko:K03924 ko00000,ko01000 Bacteria 2GK07@201174,4DNSG@85009,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) gnl|extdb|FAM19036-p1-1.1_001797 1171373.PACID_12660 1.6e-140 505.4 Propionibacteriales nodJ ko:K09694 ko02010,map02010 M00252 ko00000,ko00001,ko00002,ko02000 3.A.1.102 Bacteria 2GMXR@201174,4DNU1@85009,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter gnl|extdb|FAM19036-p1-1.1_001805 1171373.PACID_12580 2.2e-164 585.1 Actinobacteria ssuC2 ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2IFIS@201174,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_001807 1171373.PACID_12550 1e-234 818.9 Bacteria Bacteria COG1233@1,COG1233@2 NA|NA|NA Q all-trans-retinol 13,14-reductase activity gnl|extdb|FAM19036-p1-1.1_001825 1171373.PACID_12360 9e-96 356.3 Bacteria Bacteria COG0705@1,COG0705@2 NA|NA|NA S proteolysis gnl|extdb|FAM19036-p1-1.1_001832 1171373.PACID_12290 3.5e-103 380.9 Propionibacteriales ctaE GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 iJN678.ctaE Bacteria 2GKK8@201174,4DNEE@85009,COG1845@1,COG1845@2 NA|NA|NA C cytochrome c oxidase subunit III gnl|extdb|FAM19036-p1-1.1_001839 1122997.AUDD01000006_gene153 2.3e-306 1057.4 Propionibacteriales ctaD GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 2GJHX@201174,4DPQI@85009,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B gnl|extdb|FAM19036-p1-1.1_001840 1171373.PACID_12210 5.2e-144 516.9 Propionibacteriales ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 2GNXA@201174,4DNSR@85009,COG1622@1,COG1622@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) gnl|extdb|FAM19036-p1-1.1_001850 1171373.PACID_12120 8.3e-167 592.8 Propionibacteriales lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181,2.8.1.8 ko:K03644,ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07767,R07768,R07769 RC00039,RC00992,RC01978,RC02867 ko00000,ko00001,ko01000 iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 Bacteria 2GJIX@201174,4DPMN@85009,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate gnl|extdb|FAM19036-p1-1.1_001855 1171373.PACID_12070 0.0 1129.8 Propionibacteriales yjjK ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 2GJ5M@201174,4DNB0@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM19036-p1-1.1_001869 1171373.PACID_11930 1.2e-257 895.2 Propionibacteriales glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GJ2I@201174,4DNNP@85009,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase gnl|extdb|FAM19036-p1-1.1_001890 1171373.PACID_11720 7.4e-92 343.2 Actinobacteria Bacteria 2GMVK@201174,COG4243@1,COG4243@2 NA|NA|NA S Vitamin K epoxide reductase gnl|extdb|FAM19036-p1-1.1_001900 1171373.PACID_11630 1.6e-141 508.8 Propionibacteriales rpoC Bacteria 2GKXN@201174,4DQPK@85009,COG0739@1,COG0739@2 NA|NA|NA M PFAM NLP P60 protein gnl|extdb|FAM19036-p1-1.1_001928 1171373.PACID_11330 4.6e-133 480.7 Propionibacteriales znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2GJ7H@201174,4DUPX@85009,COG1108@1,COG1108@2 NA|NA|NA P ABC 3 transport family gnl|extdb|FAM19036-p1-1.1_001935 1171373.PACID_11260 9.6e-130 469.5 Propionibacteriales tcyC 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2GIZW@201174,4DNUK@85009,COG1126@1,COG1126@2 NA|NA|NA E Polar amino acid transport system gnl|extdb|FAM19036-p1-1.1_001938 1171373.PACID_11230 1.2e-29 135.2 Propionibacteriales yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 2GQG8@201174,4DSBX@85009,COG2501@1,COG2501@2 NA|NA|NA S S4 domain gnl|extdb|FAM19036-p1-1.1_001939 1171373.PACID_11220 1.7e-182 645.2 Propionibacteriales argK GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 ko:K07588 ko00000,ko01000 Bacteria 2GME8@201174,4DP5N@85009,COG1703@1,COG1703@2 NA|NA|NA E ArgK protein gnl|extdb|FAM19036-p1-1.1_001945 1171373.PACID_11150 3.4e-258 897.1 Actinobacteria lysP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0046982,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K03293,ko:K11733,ko:K16235 ko00000,ko02000 2.A.3.1,2.A.3.1.10,2.A.3.1.2 iSBO_1134.SBO_2171,iYL1228.KPN_02594 Bacteria 2I2DX@201174,COG0833@1,COG0833@2 NA|NA|NA E amino acid gnl|extdb|FAM19036-p1-1.1_001950 1171373.PACID_11100 9.9e-120 436.0 Propionibacteriales pth_2 3.1.1.29 ko:K04794 ko00000,ko01000,ko03012 Bacteria 2HEY8@201174,4DRVA@85009,COG1990@1,COG1990@2 NA|NA|NA S Peptidyl-tRNA hydrolase gnl|extdb|FAM19036-p1-1.1_001951 1171373.PACID_11090 1.8e-113 415.2 Actinobacteria 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 2IIY4@201174,COG0546@1,COG0546@2 NA|NA|NA S HAD-hyrolase-like gnl|extdb|FAM19036-p1-1.1_001967 1171373.PACID_10940 0.0 1191.0 Propionibacteriales msbA9 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4DN7W@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM19036-p1-1.1_001996 1171373.PACID_10460 1.1e-92 345.9 Propionibacteriales Bacteria 2EID2@1,2HYVC@201174,33C4E@2,4DSNI@85009 NA|NA|NA S Protein of unknown function (DUF4245) gnl|extdb|FAM19036-p1-1.1_002010 1171373.PACID_10320 1.1e-77 295.8 Actinobacteria Bacteria 2GR2U@201174,COG0454@1,COG0456@2 NA|NA|NA K Histone acetyltransferase HPA2 and related acetyltransferases gnl|extdb|FAM19036-p1-1.1_002031 1171373.PACID_10110 1.1e-124 453.0 Propionibacteriales Bacteria 2GNCK@201174,4DQBD@85009,COG4760@1,COG4760@2 NA|NA|NA S Bax inhibitor 1 like gnl|extdb|FAM19036-p1-1.1_002044 1171373.PACID_09990 6.2e-95 353.6 Propionibacteriales mazG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 Bacteria 2GNKC@201174,4DV8P@85009,COG1694@1,COG3956@2 NA|NA|NA S MazG nucleotide pyrophosphohydrolase domain gnl|extdb|FAM19036-p1-1.1_002052 1171373.PACID_09910 3.6e-111 407.5 Propionibacteriales icaR Bacteria 2GMBW@201174,4DQM1@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM19036-p1-1.1_002058 1171373.PACID_09850 7.5e-299 1032.3 Propionibacteriales pmt 2.4.1.109 ko:K00728 ko00514,ko00515,ko01100,map00514,map00515,map01100 R04072,R07620,R11399 RC00005,RC00059,RC00397 ko00000,ko00001,ko01000,ko01003 GT39 Bacteria 2I2H1@201174,4DP3Z@85009,COG1928@1,COG1928@2 NA|NA|NA O C-terminal four TMM region of protein-O-mannosyltransferase gnl|extdb|FAM19036-p1-1.1_002115 1184609.KILIM_019_00530 5.6e-100 370.2 Actinobacteria Bacteria 28Q31@1,2IFAQ@201174,2ZCKT@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002125 585531.HMPREF0063_11949 3.1e-11 74.3 Bacteria Bacteria 299R7@1,2ZWTG@2 NA|NA|NA S Helix-turn-helix XRE-family like proteins gnl|extdb|FAM19036-p1-1.1_002138 1567471.A0A0B5A5D9_9CAUD 2.4e-15 87.8 Caudovirales Viruses 4QAZF@10239,4QPH6@28883 NA|NA|NA S Protein of unknwon function (DUF3310) gnl|extdb|FAM19036-p1-1.1_002148 1120917.AQXM01000062_gene1950 1.6e-197 696.4 Micrococcaceae ko:K06919 ko00000 Bacteria 1WC6S@1268,2H1DT@201174,COG3378@1,COG3378@2 NA|NA|NA S Phage plasmid primase, P4 family gnl|extdb|FAM19036-p1-1.1_002175 1125718.HMPREF1318_2354 1.2e-13 82.0 Actinobacteria Bacteria 2BWS4@1,2GR3P@201174,32XQ0@2,4D7SW@85005 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002180 1171373.PACID_09470 2e-120 438.3 Propionibacteriales rimJ 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 2HAFI@201174,4DQM3@85009,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM19036-p1-1.1_002182 1171373.PACID_09450 3.2e-96 357.8 Propionibacteriales fthC 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 2IKWR@201174,4DR3Y@85009,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family gnl|extdb|FAM19036-p1-1.1_002191 1171373.PACID_09370 1.5e-302 1044.6 Actinobacteria Bacteria 2H1X6@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002193 1171373.PACID_09350 4.1e-173 614.0 Actinobacteria ko:K02529,ko:K06145 ko00000,ko03000 Bacteria 2GK1X@201174,COG1609@1,COG1609@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM19036-p1-1.1_002200 1171373.PACID_09280 6e-61 240.0 Actinobacteria trxA_2 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2IKP1@201174,COG0526@1,COG0526@2 NA|NA|NA CO Belongs to the thioredoxin family gnl|extdb|FAM19036-p1-1.1_002205 1171373.PACID_09230 5.2e-149 533.9 Bacteria Bacteria COG3386@1,COG3386@2 NA|NA|NA G gluconolactonase activity gnl|extdb|FAM19036-p1-1.1_002207 1171373.PACID_09200 3.2e-248 864.0 Propionibacteriales yjcD GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015208,GO:0015851,GO:0015854,GO:0016020,GO:0022857,GO:0035344,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098657,GO:0098710,GO:0098739,GO:1903716,GO:1904823 ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 2GKYD@201174,4DNIA@85009,COG2252@1,COG2252@2 NA|NA|NA S Permease family gnl|extdb|FAM19036-p1-1.1_002216 1171373.PACID_09100 3.1e-136 491.1 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity gnl|extdb|FAM19036-p1-1.1_002221 767029.HMPREF9154_0726 1.3e-12 79.0 Actinobacteria Bacteria 2CUM0@1,2IQG7@201174,32SVJ@2 NA|NA|NA S Protein of unknown function (DUF3263) gnl|extdb|FAM19036-p1-1.1_002234 1123258.AQXZ01000019_gene2790 2.3e-09 67.8 Nocardiaceae Bacteria 2I7EB@201174,4G55F@85025,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain gnl|extdb|FAM19036-p1-1.1_002260 1171373.PACID_08780 3.8e-114 417.5 Propionibacteriales Bacteria 2GN80@201174,4DQ84@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM19036-p1-1.1_002273 1171373.PACID_08660 1.4e-204 718.8 Propionibacteriales kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Bacteria 2GISV@201174,4DQ2R@85009,COG0156@1,COG0156@2 NA|NA|NA H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA gnl|extdb|FAM19036-p1-1.1_002275 1122997.AUDD01000010_gene712 3.3e-155 554.3 Propionibacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GMTH@201174,4DU6S@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002284 1171373.PACID_02680 4.9e-229 800.0 Actinobacteria Bacteria 2I8Z0@201174,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives gnl|extdb|FAM19036-p1-1.1_002294 1171373.PACID_08440 5.1e-223 780.0 Propionibacteriales metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 iAF1260.b3939,iBWG_1329.BWG_3608,iECDH10B_1368.ECDH10B_4128,iECDH1ME8569_1439.ECDH1ME8569_3808,iETEC_1333.ETEC_4208,iEcDH1_1363.EcDH1_4046,iEcHS_1320.EcHS_A4172,iEcolC_1368.EcolC_4076,iJO1366.b3939,iJR904.b3939,iUMNK88_1353.UMNK88_4777,iUTI89_1310.UTI89_C4524,iY75_1357.Y75_RS17365 Bacteria 2GJ5S@201174,4DNK6@85009,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme gnl|extdb|FAM19036-p1-1.1_002317 1171373.PACID_08060 3.6e-216 757.3 Propionibacteriales senX3 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 ko:K07636,ko:K07768,ko:K11383 ko02020,map02020 M00434,M00443,M00505 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GJY7@201174,4DP15@85009,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_002329 1171373.PACID_07940 3.3e-106 391.0 Propionibacteriales spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GM1A@201174,4DN90@85009,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family gnl|extdb|FAM19036-p1-1.1_002335 1171373.PACID_07880 1.6e-255 888.3 Propionibacteriales gumJ ko:K03328 ko00000 2.A.66.2 Bacteria 2H55P@201174,4DT00@85009,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein gnl|extdb|FAM19036-p1-1.1_002341 1171373.PACID_07820 2.5e-222 777.7 Propionibacteriales rgpA ko:K12996 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 2IBM0@201174,4DUHN@85009,COG0438@1,COG0438@2 NA|NA|NA M Domain of unknown function (DUF1972) gnl|extdb|FAM19036-p1-1.1_002343 1171373.PACID_07800 3.4e-76 290.8 Propionibacteriales tagD 2.7.7.39 ko:K00980 ko00564,map00564 R00856 RC00002 ko00000,ko00001,ko01000 Bacteria 2GKU1@201174,4DQQH@85009,COG0615@1,COG0615@2 NA|NA|NA IM Cytidylyltransferase-like gnl|extdb|FAM19036-p1-1.1_002347 1171373.PACID_07760 2.1e-148 531.6 Propionibacteriales speE 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN8I@201174,4DQ70@85009,COG0421@1,COG0421@2 NA|NA|NA E spermidine synthase gnl|extdb|FAM19036-p1-1.1_002358 1171373.PACID_07650 8.2e-161 573.2 Propionibacteriales opuAC ko:K02001,ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2I2IV@201174,4DSHN@85009,COG2113@1,COG2113@2 NA|NA|NA E Substrate binding domain of ABC-type glycine betaine transport system gnl|extdb|FAM19036-p1-1.1_002361 1171373.PACID_07610 5.8e-48 196.4 Propionibacteriales ychJ ko:K07039,ko:K09858 ko00000 Bacteria 2IQEM@201174,4DRHJ@85009,COG3012@1,COG3012@2 NA|NA|NA S Belongs to the UPF0225 family gnl|extdb|FAM19036-p1-1.1_002372 1171373.PACID_07490 2.5e-37 161.0 Actinobacteria Bacteria 2E8MQ@1,2GSZR@201174,332Z5@2 NA|NA|NA S Ribbon-helix-helix protein, copG family gnl|extdb|FAM19036-p1-1.1_002375 1171373.PACID_07460 1.9e-123 448.7 Bacteria ko:K01990,ko:K16786,ko:K16787 ko02010,map02010 M00254,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria COG1131@1,COG1131@2 NA|NA|NA V ATPase activity gnl|extdb|FAM19036-p1-1.1_002383 1171373.PACID_07380 8.9e-153 546.2 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GJZD@201174,4DPP8@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_002392 1170318.PALO_00870 6.1e-142 510.8 Propionibacteriales mntH GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015077,GO:0015078,GO:0015086,GO:0015291,GO:0015292,GO:0015293,GO:0015318,GO:0015672,GO:0015684,GO:0015691,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0034755,GO:0042221,GO:0044425,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070574,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0071577,GO:0071578,GO:0071944,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587,GO:1902600 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 iSF_1195.SF2457,iYO844.BSU04360 Bacteria 2GJSM@201174,4DSP2@85009,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein gnl|extdb|FAM19036-p1-1.1_002393 246196.MSMEI_5212 5.1e-168 597.4 Mycobacteriaceae Bacteria 233EN@1762,2HQSF@201174,COG2421@1,COG2421@2 NA|NA|NA C Acetamidase formamidase gnl|extdb|FAM19036-p1-1.1_002395 1171373.PACID_07240 6.3e-205 719.9 Propionibacteriales Bacteria 2GJEG@201174,4DN2N@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM19036-p1-1.1_002400 1171373.PACID_07170 1.1e-98 365.9 Propionibacteriales 2.7.1.48,3.6.1.55 ko:K00876,ko:K03574 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000,ko03400 Bacteria 2IRKE@201174,4DSUM@85009,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain gnl|extdb|FAM19036-p1-1.1_002401 1171373.PACID_07160 3e-246 857.4 Actinobacteria aroP GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008104,GO:0008150,GO:0008320,GO:0008324,GO:0008509,GO:0008514,GO:0008565,GO:0009977,GO:0015031,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015291,GO:0015318,GO:0015399,GO:0015405,GO:0015450,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015833,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1904680,GO:1905039 ko:K03293,ko:K11732,ko:K11734 ko00000,ko02000 2.A.3.1,2.A.3.1.1,2.A.3.1.3 iAPECO1_1312.APECO1_1472,iECW_1372.ECW_m0628,iEcE24377_1341.EcE24377A_0114,iEcolC_1368.EcolC_3070,iJN746.PP_4495,iUTI89_1310.UTI89_C0576,iWFL_1372.ECW_m0628 Bacteria 2GJ0X@201174,COG1113@1,COG1113@2 NA|NA|NA E amino acid gnl|extdb|FAM19036-p1-1.1_002412 1171373.PACID_07050 2.2e-231 808.1 Propionibacteriales 2.7.13.3 ko:K02484,ko:K07768 ko02020,map02020 M00443 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2I2DU@201174,4DNGB@85009,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain gnl|extdb|FAM19036-p1-1.1_002418 1171373.PACID_06980 9.6e-152 542.7 Actinobacteria rlmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2I8VY@201174,COG2813@1,COG2813@2 NA|NA|NA J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA gnl|extdb|FAM19036-p1-1.1_002436 1171373.PACID_06740 1.2e-274 951.8 Propionibacteriales aspA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2250,iECs_1301.ECs5120,iG2583_1286.G2583_4966,iSBO_1134.SBO_4317,iSDY_1059.SDY_4444,iSF_1195.SF4293,iSFxv_1172.SFxv_4682,iSSON_1240.SSON_4322,iS_1188.S4560,iUTI89_1310.UTI89_C4736,iYL1228.KPN_04529,iZ_1308.Z5744,ic_1306.c5222 Bacteria 2I2HG@201174,4DPWH@85009,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus gnl|extdb|FAM19036-p1-1.1_002450 1171373.PACID_06630 8.7e-102 376.3 Bacteria yusZ Bacteria COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM19036-p1-1.1_002476 1171373.PACID_06370 9e-198 696.0 Actinobacteria Bacteria 2GX7C@201174,COG2267@1,COG2267@2 NA|NA|NA I carboxylic ester hydrolase activity gnl|extdb|FAM19036-p1-1.1_002482 1171373.PACID_06300 2.6e-65 254.6 Propionibacteriales crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2GX3X@201174,4DWRM@85009,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity gnl|extdb|FAM19036-p1-1.1_002487 1171373.PACID_06250 8.8e-204 716.1 Propionibacteriales ynfM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08224 ko00000,ko02000 2.A.1.36 Bacteria 2GMWE@201174,4DTEB@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002488 1171373.PACID_06240 2.1e-180 638.3 Propionibacteriales terC ko:K05794 ko00000 Bacteria 2GIWU@201174,4DNCF@85009,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family gnl|extdb|FAM19036-p1-1.1_002495 1171373.PACID_06150 0.0 2302.7 Propionibacteriales ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 2GK9M@201174,4DNYP@85009,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) gnl|extdb|FAM19036-p1-1.1_002506 1171373.PACID_06030 0.0 1465.7 Propionibacteriales dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJKA@201174,4DP04@85009,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity gnl|extdb|FAM19036-p1-1.1_002512 1171373.PACID_05980 5.5e-226 790.0 Propionibacteriales Bacteria 2GNUF@201174,4DU7Z@85009,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM19036-p1-1.1_002518 1171373.PACID_05910 8.1e-307 1058.9 Propionibacteriales aarF Bacteria 2GJQ6@201174,4DQX3@85009,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family gnl|extdb|FAM19036-p1-1.1_002543 1171373.PACID_05700 1.3e-257 895.2 Propionibacteriales rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 ko:K03588,ko:K05364,ko:K05837 ko00550,ko04112,map00550,map04112 R04519 RC00005,RC00049 ko00000,ko00001,ko01011,ko02000,ko03036 2.A.103.1 Bacteria 2GJTI@201174,4DPN4@85009,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family gnl|extdb|FAM19036-p1-1.1_002547 1171373.PACID_05660 4.8e-134 483.8 Propionibacteriales Bacteria 2GJ9Y@201174,4DRBX@85009,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) gnl|extdb|FAM19036-p1-1.1_002548 1171373.PACID_05650 2.7e-27 127.9 Propionibacteriales crgA Bacteria 2E4NY@1,2GX73@201174,31XN3@2,4DSQV@85009 NA|NA|NA D Involved in cell division gnl|extdb|FAM19036-p1-1.1_002549 1171373.PACID_05640 9.5e-283 978.8 Propionibacteriales lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 2GKE0@201174,4DNHS@85009,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family gnl|extdb|FAM19036-p1-1.1_002550 1171373.PACID_05630 3.7e-42 177.2 Bacteria Bacteria COG0393@1,COG0393@2 NA|NA|NA S Putative heavy-metal-binding gnl|extdb|FAM19036-p1-1.1_002555 1171373.PACID_05580 1.2e-224 785.4 Actinobacteria pucG GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GM5F@201174,COG0075@1,COG0075@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM19036-p1-1.1_002569 1171373.PACID_05440 0.0 1153.3 Propionibacteriales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4DN2U@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM19036-p1-1.1_002577 1171373.PACID_05350 7.3e-74 283.1 Propionibacteriales Bacteria 2DQ01@1,2IS50@201174,32UN7@2,4DVDY@85009 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002584 1171373.PACID_05270 2.3e-245 854.7 Propionibacteriales cydD ko:K16013,ko:K16014 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 2I2DP@201174,4DP3V@85009,COG4988@1,COG4988@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM19036-p1-1.1_002591 1171373.PACID_05200 4.6e-112 410.6 Propionibacteriales ko:K05799 ko00000,ko03000 Bacteria 2GZJA@201174,4DV1Q@85009,COG2186@1,COG2186@2 NA|NA|NA K FCD gnl|extdb|FAM19036-p1-1.1_002602 1170318.PALO_09595 1.3e-245 855.9 Actinobacteria ko:K12989 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 2GJI0@201174,COG0297@1,COG0297@2,COG0438@1,COG0438@2 NA|NA|NA M glycosyl transferase group 1 gnl|extdb|FAM19036-p1-1.1_002612 188626.HMPREF0321_2010 2.1e-30 138.7 Bacteria Bacteria COG0110@1,COG0110@2 NA|NA|NA S O-acyltransferase activity gnl|extdb|FAM19036-p1-1.1_002635 1171373.PACID_05040 4.5e-180 637.1 Actinobacteria 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 2GIS3@201174,COG0604@1,COG0604@2 NA|NA|NA C alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_002643 1171373.PACID_04960 4.5e-247 860.1 Propionibacteriales ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 2GJFE@201174,4DPIA@85009,COG1252@1,COG1252@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase gnl|extdb|FAM19036-p1-1.1_002652 1171373.PACID_04890 1.6e-205 721.8 Propionibacteriales wblG Bacteria 2GNUU@201174,4DTBU@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 gnl|extdb|FAM19036-p1-1.1_002655 1171373.PACID_04860 1.3e-210 738.8 Actinobacteria Bacteria 2HA9B@201174,COG3307@1,COG3307@2 NA|NA|NA M O-antigen ligase like membrane protein gnl|extdb|FAM19036-p1-1.1_002683 1171373.PACID_04590 3e-212 744.2 Propionibacteriales Bacteria 2HZNP@201174,4DTDM@85009,COG5542@1,COG5542@2 NA|NA|NA S integral membrane protein gnl|extdb|FAM19036-p1-1.1_002684 1171373.PACID_04580 5.3e-265 919.8 Propionibacteriales Bacteria 2GJYA@201174,4DPN0@85009,COG5650@1,COG5650@2 NA|NA|NA S integral membrane protein gnl|extdb|FAM19036-p1-1.1_002687 1171373.PACID_04550 3e-154 551.2 Propionibacteriales ywfM ko:K03298 ko00000,ko02000 2.A.7.3 Bacteria 2GMPJ@201174,4DQV4@85009,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM19036-p1-1.1_002689 1171373.PACID_04530 1.3e-227 795.4 Actinobacteria Bacteria 2GKAT@201174,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 gnl|extdb|FAM19036-p1-1.1_002704 1171373.PACID_04370 5e-203 713.8 Propionibacteriales ko:K03699 ko00000,ko02042 Bacteria 2GKN5@201174,4DNK7@85009,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain gnl|extdb|FAM19036-p1-1.1_002715 1171373.PACID_04270 2.1e-109 401.7 Propionibacteriales apl 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2GN43@201174,4DQ7V@85009,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein gnl|extdb|FAM19036-p1-1.1_002725 1170318.PALO_00065 0.0 1169.5 Propionibacteriales hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_0688 Bacteria 2GP10@201174,4DP6B@85009,COG2987@1,COG2987@2 NA|NA|NA E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate gnl|extdb|FAM19036-p1-1.1_002761 1171373.PACID_03870 5.7e-277 959.5 Propionibacteriales Bacteria 2GMZX@201174,4DQAY@85009,COG2826@1,COG2826@2 NA|NA|NA L Integrase, catalytic region gnl|extdb|FAM19036-p1-1.1_002765 327277.JHAL01000002_gene429 1.8e-09 68.6 Actinobacteria Bacteria 2DZ3F@1,2GYRG@201174,34CAH@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002793 1171373.PACID_03520 1.2e-141 509.2 Propionibacteriales GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K11206 ko00000,ko01000 Bacteria 2GMQA@201174,4DNQW@85009,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase gnl|extdb|FAM19036-p1-1.1_002802 1171373.PACID_03240 8.1e-82 309.7 Actinobacteria Bacteria 2CM5B@1,2IRBQ@201174,32SDR@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002803 1171373.PACID_03230 0.0 1140.6 Actinobacteria Bacteria 2IEWM@201174,COG1479@1,COG1479@2,COG3472@1,COG3472@2 NA|NA|NA K Protein of unknown function DUF262 gnl|extdb|FAM19036-p1-1.1_002806 706439.HMPREF9057_00401 2.2e-103 382.5 Actinobacteria Bacteria 2IAJ1@201174,4D3CU@85005,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain gnl|extdb|FAM19036-p1-1.1_002827 1171373.PACID_03060 1.4e-151 542.3 Actinobacteria pabC 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GN5Z@201174,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase gnl|extdb|FAM19036-p1-1.1_002851 1171373.PACID_02810 8.7e-108 396.4 Propionibacteriales ko:K07149 ko00000 Bacteria 2GKA1@201174,4DQWJ@85009,COG2364@1,COG2364@2 NA|NA|NA S membrane gnl|extdb|FAM19036-p1-1.1_002867 1171373.PACID_02630 0.0 1125.9 Actinobacteria hcp GO:0000302,GO:0001505,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0017144,GO:0034641,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0044237,GO:0044248,GO:0044270,GO:0046209,GO:0046210,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748,GO:2001057 1.7.99.1 ko:K05601 ko00910,map00910 R00143 RC02797 ko00000,ko00001,ko01000 Bacteria 2I9NG@201174,COG0369@1,COG1151@2 NA|NA|NA C Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O gnl|extdb|FAM19036-p1-1.1_002877 1171373.PACID_02530 6.6e-304 1049.3 Propionibacteriales ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,4DN37@85009,COG1123@1,COG4172@2 NA|NA|NA O Belongs to the ABC transporter superfamily gnl|extdb|FAM19036-p1-1.1_002884 591158.SSMG_08414 5e-19 100.5 Actinobacteria Bacteria 2GRAD@201174,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain gnl|extdb|FAM19036-p1-1.1_002906 1171373.PACID_02330 0.0 1785.8 Actinobacteria nirK 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 Bacteria 2GPUP@201174,COG2132@1,COG2132@2,COG4454@1,COG4454@2 NA|NA|NA Q Multicopper oxidase gnl|extdb|FAM19036-p1-1.1_002905 1171373.PACID_02340 1.1e-192 679.1 Actinobacteria 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 Bacteria 2HG56@201174,COG4243@1,COG4243@2 NA|NA|NA Q Vitamin k epoxide reductase gnl|extdb|FAM19036-p1-1.1_002920 1171373.PACID_02180 1.3e-52 212.6 Bacteria pccA 6.4.1.3 ko:K01965 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria COG4770@1,COG4770@2 NA|NA|NA I CoA carboxylase activity gnl|extdb|FAM19036-p1-1.1_002922 1171373.PACID_02160 2.9e-279 967.2 Propionibacteriales 2.1.3.1,2.1.3.15,6.4.1.3 ko:K01966,ko:K17489 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R00353,R01859 RC00040,RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRU@201174,4DNBQ@85009,COG4799@1,COG4799@2 NA|NA|NA I Carboxyl transferase domain gnl|extdb|FAM19036-p1-1.1_002937 1171373.PACID_02020 8.7e-183 646.4 Propionibacteriales ko:K07552 ko00000,ko02000 2.A.1.2 Bacteria 2GJK6@201174,4DQNB@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_002947 1171373.PACID_01910 2.3e-81 308.1 Propionibacteriales 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 R07177 ko00000,ko00001,ko01000 3.D.4.9 Bacteria 2C3A2@1,2I9BD@201174,2ZZP3@2,4DQXG@85009 NA|NA|NA S PFAM DoxX family protein gnl|extdb|FAM19036-p1-1.1_002960 1171373.PACID_01770 2.4e-223 781.2 Propionibacteriales Bacteria 2GNEG@201174,4DQIV@85009,COG1473@1,COG1473@2 NA|NA|NA S Peptidase dimerisation domain gnl|extdb|FAM19036-p1-1.1_002971 1171373.PACID_01660 2.1e-48 198.0 Actinobacteria Bacteria 2GS68@201174,COG0695@1,COG0695@2 NA|NA|NA O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins gnl|extdb|FAM19036-p1-1.1_002973 1171373.PACID_01640 1.1e-291 1008.4 Actinobacteria 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJ4@201174,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase gnl|extdb|FAM19036-p1-1.1_002981 1171373.PACID_01570 3e-257 894.0 Propionibacteriales 2.7.13.3 ko:K02484,ko:K07768 ko02020,map02020 M00443 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2I2DU@201174,4DNGB@85009,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain gnl|extdb|FAM19036-p1-1.1_002985 446470.Snas_5252 1.4e-78 299.7 Glycomycetales ko:K07015 ko00000 Bacteria 2I2PK@201174,4EZ2N@85014,COG1215@1,COG1215@2,COG2246@1,COG2246@2 NA|NA|NA M Glycosyltransferase like family 2 gnl|extdb|FAM19036-p1-1.1_002987 1171373.PACID_01530 3.4e-130 471.5 Actinobacteria Bacteria 2DBC0@1,2I65C@201174,2Z8BE@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002994 562973.HMPREF0059_00697 3.2e-43 181.0 Actinobacteria Bacteria 2IFY3@201174,4D6DP@85005,COG4683@1,COG4683@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) gnl|extdb|FAM19036-p1-1.1_002996 1171373.PACID_01450 6.3e-114 416.8 Propionibacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4DNEX@85009,COG1136@1,COG1136@2 NA|NA|NA V COG1136 ABC-type antimicrobial peptide transport system, ATPase component gnl|extdb|FAM19036-p1-1.1_002998 1171373.PACID_01430 1.9e-80 305.1 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation gnl|extdb|FAM19036-p1-1.1_003003 1171373.PACID_01380 4.2e-46 190.3 Actinobacteria ko:K07075 ko00000 Bacteria 2IT4H@201174,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase domain gnl|extdb|FAM19036-p1-1.1_003006 1171373.PACID_01350 4e-237 827.0 Propionibacteriales 2.7.4.9 ko:K00943,ko:K08217,ko:K18833 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 br01600,ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.2,2.A.1.21.22 Bacteria 2GK5A@201174,4DQ23@85009,COG2270@1,COG2270@2 NA|NA|NA S Major facilitator Superfamily gnl|extdb|FAM19036-p1-1.1_003016 1171373.PACID_01250 1.6e-227 795.0 Propionibacteriales virB11 ko:K02283,ko:K03196,ko:K12083 ko03070,ko05120,map03070,map05120 M00333,M00564 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.7,3.A.7.3.1 Bacteria 2I3XU@201174,4DNAT@85009,COG0630@1,COG0630@2 NA|NA|NA NU Type II/IV secretion system protein gnl|extdb|FAM19036-p1-1.1_003018 1171373.PACID_01220 1.1e-73 282.7 Propionibacteriales Bacteria 2IR93@201174,4DW2A@85009,COG1261@1,COG1261@2 NA|NA|NA NO SAF domain gnl|extdb|FAM19036-p1-1.1_003019 1171373.PACID_01210 4.4e-83 313.9 Actinobacteria Bacteria 2C6VN@1,2IPJ7@201174,334YM@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_003025 1171373.PACID_01150 4.5e-261 906.7 Propionibacteriales M1-530 Bacteria 2DB83@1,2IAN4@201174,2Z7Q0@2,4DT7I@85009 NA|NA|NA S Protein of unknown function (DUF4127) gnl|extdb|FAM19036-p1-1.1_003032 1171373.PACID_01080 3.8e-128 464.2 Propionibacteriales 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2GIZW@201174,4DP52@85009,COG1126@1,COG1126@2 NA|NA|NA E amino acid ABC transporter, ATP-binding protein gnl|extdb|FAM19036-p1-1.1_003053 754252.PFREUD_19260 2.1e-209 734.9 Propionibacteriales 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2HBVS@201174,4DU4P@85009,COG0001@1,COG0001@2 NA|NA|NA H Aminotransferase class-III gnl|extdb|FAM19036-p1-1.1_003064 1171373.PACID_00320 1.1e-226 792.3 Propionibacteriales arsB Bacteria 2GMQJ@201174,4DN5A@85009,COG1055@1,COG1055@2 NA|NA|NA P Bacterial Na+/H+ antiporter B (NhaB) gnl|extdb|FAM19036-p1-1.1_003073 1171373.PACID_00240 2.1e-157 561.6 Propionibacteriales Bacteria 2GWHQ@201174,4DQKH@85009,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM19036-p1-1.1_003085 1171373.PACID_00120 2.3e-114 418.3 Propionibacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GKZP@201174,4DR9G@85009,COG3266@1,COG3266@2 NA|NA|NA S Transmembrane domain of unknown function (DUF3566) gnl|extdb|FAM19036-p1-1.1_003100 1171373.PACID_34300 1.7e-62 245.7 Propionibacteriales jag ko:K06346,ko:K09749 ko00000 Bacteria 2GPZK@201174,4DQRW@85009,COG1847@1,COG1847@2 NA|NA|NA S Putative single-stranded nucleic acids-binding domain gnl|extdb|FAM19036-p1-1.1_003101 1171373.PACID_34290 2.4e-47 194.5 Propionibacteriales sugE ko:K11741 ko00000,ko02000 2.A.7.1 Bacteria 2IQND@201174,4DVSW@85009,COG2076@1,COG2076@2 NA|NA|NA P Small Multidrug Resistance protein gnl|extdb|FAM19036-p1-1.1_003102 1171373.PACID_34280 8.2e-108 396.4 Propionibacteriales rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 2GM9Z@201174,4DR7I@85009,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA gnl|extdb|FAM19036-p1-1.1_003108 1171373.PACID_34220 1e-120 439.5 Propionibacteriales surf1 ko:K14998 ko00000,ko03029 3.D.4.8 Bacteria 2GMGB@201174,4DS42@85009,COG3346@1,COG3346@2 NA|NA|NA S SURF1 family gnl|extdb|FAM19036-p1-1.1_003110 1171373.PACID_34190 3.5e-260 903.7 Propionibacteriales avtA ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 R01939 RC00006 ko00000,ko00001,ko01000 Bacteria 2GITW@201174,4DPAN@85009,COG1167@1,COG1167@2 NA|NA|NA EK Alanine-glyoxylate amino-transferase gnl|extdb|FAM19036-p1-1.1_003130 1171373.PACID_33970 9.2e-206 722.6 Actinobacteria 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 2GM8C@201174,COG1062@1,COG1062@2 NA|NA|NA C alcohol dehydrogenase gnl|extdb|FAM19036-p1-1.1_003142 1122138.AQUZ01000083_gene3524 1.7e-87 329.7 Propionibacteriales Bacteria 2HYBN@201174,4DUHR@85009,COG5433@1,COG5433@2 NA|NA|NA L DDE_Tnp_1-associated gnl|extdb|FAM19036-p1-1.1_003178 1122997.AUDD01000025_gene1191 1e-234 818.9 Propionibacteriales hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJTQ@201174,4DNBP@85009,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX gnl|extdb|FAM19036-p1-1.1_003198 1171373.PACID_33880 5.2e-161 573.5 Actinobacteria rluA 5.4.99.28,5.4.99.29 ko:K06177 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ2Z@201174,COG0564@1,COG0564@2 NA|NA|NA J pseudouridine synthase gnl|extdb|FAM19036-p1-1.1_003200 1171373.PACID_33860 2.9e-54 217.6 Propionibacteriales Bacteria 2IQNN@201174,4DR26@85009,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix gnl|extdb|FAM19036-p1-1.1_003205 1171373.PACID_33800 2.2e-168 598.2 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GKJI@201174,4DP03@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_003225 1171373.PACID_33600 2e-58 231.5 Propionibacteriales glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 2GKHX@201174,4DQ1K@85009,COG1929@1,COG1929@2 NA|NA|NA G Glycerate kinase family gnl|extdb|FAM19036-p1-1.1_003226 1171373.PACID_33590 2.7e-163 581.3 Propionibacteriales ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 2GMFK@201174,4DNMY@85009,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel gnl|extdb|FAM19036-p1-1.1_003256 1171373.PACID_33250 1.1e-209 735.7 Propionibacteriales lppS GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0030312,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 Bacteria 2GJBA@201174,4DN7Y@85009,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain gnl|extdb|FAM19036-p1-1.1_003266 1171373.PACID_33140 0.0 1483.0 Propionibacteriales pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Bacteria 2GK6W@201174,4DPJ3@85009,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis gnl|extdb|FAM19036-p1-1.1_003278 1171373.PACID_32990 3e-68 264.2 Propionibacteriales Bacteria 2IIU7@201174,4DRAD@85009,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain gnl|extdb|FAM19036-p1-1.1_003280 77635.BISU_0316 6.8e-33 146.4 Bifidobacteriales Bacteria 2IQNN@201174,4D13S@85004,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix gnl|extdb|FAM19036-p1-1.1_003285 1171373.PACID_32920 1.6e-138 498.8 Propionibacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GMTH@201174,4DRAE@85009,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_003286 1171373.PACID_32910 1.1e-142 512.7 Propionibacteriales ko:K02025,ko:K05814,ko:K10118,ko:K10201,ko:K10241,ko:K15771,ko:K17316 ko02010,map02010 M00196,M00198,M00205,M00206,M00207,M00491,M00605 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30 Bacteria 2GKBJ@201174,4DQM2@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM19036-p1-1.1_003290 1171373.PACID_32870 3.5e-180 637.5 Propionibacteriales yegV GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 Bacteria 2IA3T@201174,4DUEH@85009,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM19036-p1-1.1_003291 1171373.PACID_32860 5.8e-149 533.5 Actinobacteria pabC 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GN5Z@201174,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase gnl|extdb|FAM19036-p1-1.1_003319 1171373.PACID_32670 3.3e-135 487.6 Actinobacteria ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IAY5@201174,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter gnl|extdb|FAM19036-p1-1.1_000818 1171373.PACID_24120 3.9e-31 141.0 Propionibacteriales lytR2 Bacteria 2GJJJ@201174,4DPY2@85009,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain gnl|extdb|FAM19036-p1-1.1_000885 1171373.PACID_23330 1.3e-33 148.3 Bacteria Bacteria COG0553@1,COG0553@2 NA|NA|NA L helicase activity gnl|extdb|FAM19036-p1-1.1_000960 1171373.PACID_22330 2.5e-147 528.1 Propionibacteriales surf1 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 ko:K14998 ko00000,ko03029 3.D.4.8 Bacteria 2GR90@201174,4DR52@85009,COG3346@1,COG3346@2 NA|NA|NA S SURF1 family gnl|extdb|FAM19036-p1-1.1_001400 1171373.PACID_17170 2.5e-09 67.4 Actinobacteria ltaE 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 2GJ0V@201174,COG2008@1,COG2008@2 NA|NA|NA E Threonine aldolase gnl|extdb|FAM19036-p1-1.1_001715 1229781.C272_13283 3.5e-11 74.3 Brevibacteriaceae Bacteria 2GK2A@201174,4F9TD@85019,COG5421@1,COG5421@2 NA|NA|NA L Transposase DDE domain gnl|extdb|FAM19036-p1-1.1_001910 1122998.AUHZ01000005_gene887 1.3e-19 103.2 Actinobacteria Bacteria 29WQV@1,2GZ2Y@201174,30IBV@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002288 1171373.PACID_08500 3.1e-186 657.5 Bacteria Bacteria 2E2S2@1,32XUD@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002621 1479623.JHEL01000015_gene653 6.3e-09 68.2 Actinobacteria Bacteria 2DYW4@1,2H7PT@201174,34BDN@2 NA|NA|NA gnl|extdb|FAM19036-p1-1.1_002746 1171373.PACID_04030 1.5e-15 87.8 Bacteria cdr Bacteria COG0446@1,COG0446@2 NA|NA|NA Q pyridine nucleotide-disulphide oxidoreductase gnl|extdb|FAM19036-p1-1.1_003217 1171373.PACID_33670 0.0 1318.9 Propionibacteriales Bacteria 2GN00@201174,4DQW4@85009,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV # 2898 queries scanned # Total time (seconds): 1695.52463603 # Rate: 1.71 q/s