# emapper version: emapper-1.0.3-35-g63c274b emapper DB: 2.0 # command: ./emapper.py --cpu 6 -i /data/shared/emapper_jobs/user_data/MM_in0imkw6/query_seqs.fa --output query_seqs.fa --output_dir /data/shared/emapper_jobs/user_data/MM_in0imkw6 -m diamond -d none --tax_scope auto --go_evidence non-electronic --target_orthologs all --seed_ortholog_evalue 0.001 --seed_ortholog_score 60 --query-cover 20 --subject-cover 0 --override --temp_dir /data/shared/emapper_jobs/user_data/MM_in0imkw6 # time: Fri May 29 23:39:30 2020 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction gnl|extdb|FAM14217-p1-1.1_000009 1403948.Q618_VCMC00001G0154 2e-32 146.4 Actinobacteria Bacteria 2DMZU@1,2HZJY@201174,32UNG@2,4D7QE@85005 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000010 356851.JOAN01000003_gene1472 3.3e-36 158.7 Micromonosporales 3.1.11.5,3.6.4.12 ko:K01144,ko:K16898 ko00000,ko01000,ko03400 Bacteria 2ICR2@201174,4DIM7@85008,COG1074@1,COG1074@2 NA|NA|NA L PDDEXK-like domain of unknown function (DUF3799) gnl|extdb|FAM14217-p1-1.1_000011 1489678.RDMS_01785 2.3e-12 79.3 Bacteria Bacteria 2CBW9@1,34C12@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000014 1027371.GOALK_093_00720 2.5e-43 182.6 Bacteria Bacteria COG3617@1,COG3617@2 NA|NA|NA K BRO family, N-terminal domain gnl|extdb|FAM14217-p1-1.1_000016 1206732.BAGD01000258_gene5869 2.8e-09 67.8 Nocardiaceae Bacteria 2BIQN@1,2HJ0N@201174,32CY1@2,4G53Y@85025 NA|NA|NA K Cro/C1-type HTH DNA-binding domain gnl|extdb|FAM14217-p1-1.1_000018 1122997.AUDD01000007_gene828 1.1e-77 297.4 Propionibacteriales int ko:K14059 ko00000 Bacteria 2GMMI@201174,4DP4K@85009,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family gnl|extdb|FAM14217-p1-1.1_000019 754252.PFREUD_02870 8.8e-90 336.3 Propionibacteriales dps ko:K04047 ko00000,ko03036 Bacteria 2IFDP@201174,4DQZR@85009,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family gnl|extdb|FAM14217-p1-1.1_000022 754252.PFREUD_02830 6.7e-190 669.8 Propionibacteriales yhfT 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2I908@201174,4DV3A@85009,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme gnl|extdb|FAM14217-p1-1.1_000023 754252.PFREUD_02820 5.6e-206 723.4 Actinobacteria vraB 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GM29@201174,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family gnl|extdb|FAM14217-p1-1.1_000024 754252.PFREUD_02810 1.1e-275 955.3 Actinobacteria uhpT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015119,GO:0015291,GO:0015297,GO:0015301,GO:0015315,GO:0015318,GO:0015526,GO:0015605,GO:0015698,GO:0015711,GO:0015712,GO:0015748,GO:0015760,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:0099516,GO:1901264,GO:1901505 ko:K02445,ko:K07784 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.4.1,2.A.1.4.3 iECSF_1327.ECSF_3513 Bacteria 2IE3Y@201174,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000025 754252.PFREUD_02800 9.3e-150 536.2 Bacteria 3.1.22.1,3.1.3.25 ko:K01092,ko:K01158 ko00521,ko00562,ko01100,ko04070,ko04142,map00521,map00562,map01100,map04070,map04142 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria COG0483@1,COG0483@2 NA|NA|NA G inositol monophosphate 1-phosphatase activity gnl|extdb|FAM14217-p1-1.1_000028 754252.PFREUD_02720 9.3e-77 292.7 Actinobacteria gmm GO:0000287,GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0015926,GO:0016787,GO:0016798,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047917 3.6.1.55 ko:K03207,ko:K03574 ko00000,ko01000,ko03400 iECBD_1354.ECBD_1604 Bacteria 2IQEA@201174,COG1051@1,COG1051@2 NA|NA|NA F Belongs to the NUDIX hydrolase family gnl|extdb|FAM14217-p1-1.1_000030 754252.PFREUD_02700 3.7e-268 930.2 Propionibacteriales glpT ko:K02445 ko00000,ko02000 2.A.1.4.3 Bacteria 2H9HJ@201174,4DMYK@85009,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000031 754252.PFREUD_02670 1.9e-127 461.8 Actinobacteria mgtC ko:K07507 ko00000,ko02000 9.B.20 Bacteria 2GJF0@201174,COG1285@1,COG1285@2 NA|NA|NA S PFAM MgtC SapB transporter gnl|extdb|FAM14217-p1-1.1_000032 754252.PFREUD_02660 6.1e-310 1069.3 Propionibacteriales Bacteria 2GK31@201174,4DN1J@85009,COG1409@1,COG1409@2 NA|NA|NA M Calcineurin-like phosphoesterase gnl|extdb|FAM14217-p1-1.1_000033 754252.PFREUD_02650 4.3e-253 880.2 Actinobacteria ko:K08368 ko00000,ko02000 2.A.1 Bacteria 2GJF6@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000035 754252.PFREUD_02640 2.3e-32 144.4 Actinobacteria bglB 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 2GJ5H@201174,COG1472@1,COG1472@2 NA|NA|NA G hydrolase, family 3 gnl|extdb|FAM14217-p1-1.1_000036 754252.PFREUD_02640 0.0 1351.7 Actinobacteria bglB 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 2GJ5H@201174,COG1472@1,COG1472@2 NA|NA|NA G hydrolase, family 3 gnl|extdb|FAM14217-p1-1.1_000037 754252.PFREUD_02630 1.1e-121 442.6 Actinobacteria Bacteria 2I8DN@201174,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000038 754252.PFREUD_02620 8.4e-187 659.4 Propionibacteriales galE1 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMCW@201174,4DP83@85009,COG1087@1,COG1087@2 NA|NA|NA M Polysaccharide biosynthesis protein gnl|extdb|FAM14217-p1-1.1_000039 754252.PFREUD_02610 1.3e-246 858.6 Actinobacteria ko:K03319 ko00000 2.A.47 Bacteria 2IEZE@201174,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region gnl|extdb|FAM14217-p1-1.1_000041 754252.PFREUD_02590 6.8e-144 516.9 Propionibacteriales siuS16 ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2I1A6@201174,4DWT6@85009,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein gnl|extdb|FAM14217-p1-1.1_000044 754252.PFREUD_02560 9.9e-150 536.2 Propionibacteriales 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 2GJ49@201174,4DQ2B@85009,COG1120@1,COG1120@2 NA|NA|NA HP ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_000045 101510.RHA1_ro02998 1e-172 613.2 Nocardiaceae Bacteria 2GJF6@201174,4G9G6@85025,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000046 765420.OSCT_0698 1.2e-68 266.9 Chloroflexia iolG 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2G6CR@200795,377GR@32061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM14217-p1-1.1_000047 1120944.JONS01000032_gene1313 4.5e-126 457.6 Actinobacteria 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 Bacteria 2GJKJ@201174,4D48V@85005,COG1082@1,COG1082@2 NA|NA|NA G inosose dehydratase gnl|extdb|FAM14217-p1-1.1_000048 1120944.JONS01000032_gene1312 3.3e-80 305.4 Actinobacteria ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4D69K@85005,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM14217-p1-1.1_000050 754252.PFREUD_02540 9.8e-229 799.3 Propionibacteriales rkpK 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQB@201174,4DPN1@85009,COG1004@1,COG1004@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family gnl|extdb|FAM14217-p1-1.1_000052 754252.PFREUD_02520 0.0 1163.7 Propionibacteriales sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GIU5@201174,4DP3W@85009,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit gnl|extdb|FAM14217-p1-1.1_000053 754252.PFREUD_02510 2.6e-51 207.6 Actinobacteria fixX ko:K03855 ko00000 Bacteria 2IREY@201174,COG2440@1,COG2440@2 NA|NA|NA C Psort location Cytoplasmic, score gnl|extdb|FAM14217-p1-1.1_000054 754252.PFREUD_02500 3.7e-246 857.1 Bacteria fixC ko:K00313 ko00000,ko01000 Bacteria COG0644@1,COG0644@2 NA|NA|NA C geranylgeranyl reductase activity gnl|extdb|FAM14217-p1-1.1_000055 754252.PFREUD_02490 7.3e-150 536.6 Actinobacteria etfA ko:K03522 ko00000,ko04147 Bacteria 2GJWH@201174,COG2025@1,COG2025@2 NA|NA|NA C Electron transfer flavoprotein gnl|extdb|FAM14217-p1-1.1_000056 754252.PFREUD_02480 4.7e-129 467.2 Bacteria ko:K03521 ko00000 Bacteria COG2086@1,COG2086@2 NA|NA|NA C electron transfer activity gnl|extdb|FAM14217-p1-1.1_000059 754252.PFREUD_02450 7.1e-177 626.3 Propionibacteriales Bacteria 2GJJI@201174,4DP3A@85009,COG2030@1,COG2030@2 NA|NA|NA I MaoC like domain gnl|extdb|FAM14217-p1-1.1_000062 754252.PFREUD_02420 1.7e-223 781.6 Propionibacteriales caiA 1.3.8.13 ko:K08297 ko00000,ko01000 Bacteria 2GIX8@201174,4DT02@85009,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain gnl|extdb|FAM14217-p1-1.1_000064 419947.MRA_3470 1.1e-39 169.9 Mycobacteriaceae ko:K07497 ko00000 Bacteria 234CZ@1762,2GNRT@201174,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase, catalytic gnl|extdb|FAM14217-p1-1.1_000065 754252.PFREUD_25130 9.3e-258 895.6 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000066 754252.PFREUD_23090 6.4e-131 473.4 Actinobacteria dltE ko:K14189 ko00000,ko01000 Bacteria 2GP7V@201174,COG3967@1,COG3967@2 NA|NA|NA M Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM14217-p1-1.1_000067 754252.PFREUD_23080 1.1e-169 602.4 Actinobacteria panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 2I3AM@201174,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid gnl|extdb|FAM14217-p1-1.1_000068 754252.PFREUD_23070 3.8e-146 524.2 Actinobacteria Bacteria 2IIAF@201174,COG1737@1,COG1737@2 NA|NA|NA K SIS domain gnl|extdb|FAM14217-p1-1.1_000069 754252.PFREUD_23060 2.9e-122 444.9 Propionibacteriales Bacteria 2GMPU@201174,4DS3N@85009,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM14217-p1-1.1_000071 861360.AARI_06640 1.3e-98 365.9 Micrococcaceae flpA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1W9PR@1268,2IKTT@201174,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein gnl|extdb|FAM14217-p1-1.1_000072 321955.AAGP01000051_gene3591 2.9e-29 134.0 Brevibacteriaceae ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 2GQMZ@201174,4FAKK@85019,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain gnl|extdb|FAM14217-p1-1.1_000073 861360.AARI_06660 1.2e-306 1058.5 Micrococcaceae copA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1W7NP@1268,2GIRF@201174,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase gnl|extdb|FAM14217-p1-1.1_000075 754252.PFREUD_24460 2.1e-151 541.6 Propionibacteriales ko:K07497 ko00000 Bacteria 2GJ3V@201174,4DUKR@85009,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome gnl|extdb|FAM14217-p1-1.1_000076 754252.PFREUD_02390 3e-165 587.8 Propionibacteriales Bacteria 2HY2W@201174,4DNGK@85009,COG1737@1,COG1737@2 NA|NA|NA K Transcriptional regulator, RpiR family gnl|extdb|FAM14217-p1-1.1_000077 1122998.AUHZ01000019_gene1682 0.0 2144.8 Propionibacteriales lacZ 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GMAT@201174,4DPD7@85009,COG3250@1,COG3250@2 NA|NA|NA G Beta galactosidase small chain gnl|extdb|FAM14217-p1-1.1_000078 1171373.PACID_03900 2.5e-253 880.9 Actinobacteria gph ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 2HD4Y@201174,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM14217-p1-1.1_000079 1122998.AUHZ01000019_gene1684 2.2e-190 671.4 Propionibacteriales galE1 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMCW@201174,4DP83@85009,COG1087@1,COG1087@2 NA|NA|NA M Polysaccharide biosynthesis protein gnl|extdb|FAM14217-p1-1.1_000080 754252.PFREUD_24450 4.8e-254 883.2 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000081 754252.PFREUD_24440 7.7e-258 896.0 Propionibacteriales Bacteria 2GMZX@201174,4DQAY@85009,COG2826@1,COG2826@2 NA|NA|NA L Integrase, catalytic region gnl|extdb|FAM14217-p1-1.1_000082 754252.PFREUD_02330 7.6e-255 885.9 Propionibacteriales merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 2GJJK@201174,4DNX4@85009,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM14217-p1-1.1_000084 754252.PFREUD_24830 1.1e-217 762.3 Propionibacteriales Bacteria 2GMZX@201174,4DQAY@85009,COG2826@1,COG2826@2 NA|NA|NA L Integrase, catalytic region gnl|extdb|FAM14217-p1-1.1_000086 754252.PFREUD_02320 1.7e-201 708.8 Propionibacteriales ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ3@201174,4DQN3@85009,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like peptidase domain gnl|extdb|FAM14217-p1-1.1_000087 754252.PFREUD_02310 3.8e-212 744.2 Propionibacteriales pepA ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ3@201174,4DQN3@85009,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like peptidase domain gnl|extdb|FAM14217-p1-1.1_000089 754252.PFREUD_02290 0.0 2315.0 Actinobacteria 4.1.1.38 ko:K20370 ko00620,ko01100,map00620,map01100 R00346 RC02741 ko00000,ko00001,ko01000 Bacteria 28HY3@1,2H218@201174,2Z83I@2 NA|NA|NA S phosphoenolpyruvate carboxykinase (diphosphate) activity gnl|extdb|FAM14217-p1-1.1_000090 754252.PFREUD_02270 9.5e-97 359.4 Actinobacteria Bacteria 2BBAF@1,2IM1Z@201174,324T6@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000091 754252.PFREUD_02260 2.4e-161 574.7 Actinobacteria yeaE Bacteria 2I5YH@201174,COG0656@1,COG0656@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM14217-p1-1.1_000092 754252.PFREUD_02250 5.8e-120 436.8 Propionibacteriales trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01664,ko:K13950 ko00790,map00790 R01716 RC00010,RC01418 ko00000,ko00001,ko01000 Bacteria 2GJUX@201174,4DNQV@85009,COG0512@1,COG0512@2 NA|NA|NA EH Peptidase C26 gnl|extdb|FAM14217-p1-1.1_000093 754252.PFREUD_02240 1.8e-125 455.3 Propionibacteriales Bacteria 2GJ9Y@201174,4DRBX@85009,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) gnl|extdb|FAM14217-p1-1.1_000094 754252.PFREUD_02230 1e-31 142.5 Propionibacteriales crgA Bacteria 2E4NY@1,2GX73@201174,31XN3@2,4DSQV@85009 NA|NA|NA D Involved in cell division gnl|extdb|FAM14217-p1-1.1_000095 754252.PFREUD_02220 1.8e-192 678.3 Actinobacteria Bacteria 2I8IU@201174,COG0648@1,COG0648@2 NA|NA|NA L Domain of unknown function (DUF4862) gnl|extdb|FAM14217-p1-1.1_000096 754252.PFREUD_02210 2.2e-214 751.5 Propionibacteriales pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GM0D@201174,4DPHS@85009,COG0508@1,COG0508@2 NA|NA|NA C e3 binding domain gnl|extdb|FAM14217-p1-1.1_000097 754252.PFREUD_02200 6.8e-189 666.4 Propionibacteriales pdhB GO:0003674,GO:0005488,GO:0005515,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05355,iYO844.BSU14590 Bacteria 2GKFE@201174,4DNN8@85009,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, pyrimidine binding domain gnl|extdb|FAM14217-p1-1.1_000098 754252.PFREUD_02190 2.2e-215 754.6 Propionibacteriales pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GK3W@201174,4DNN1@85009,COG1071@1,COG1071@2 NA|NA|NA C dehydrogenase, E1 component gnl|extdb|FAM14217-p1-1.1_000099 754252.PFREUD_02180 1.9e-135 488.4 Actinobacteria 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 2H9ND@201174,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase gnl|extdb|FAM14217-p1-1.1_000101 754252.PFREUD_02160 3.1e-290 1003.8 Propionibacteriales ydiF Bacteria 2GJHN@201174,4DPS7@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM14217-p1-1.1_000102 754252.PFREUD_02150 9.8e-113 413.3 Actinobacteria ksgA 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 2I2II@201174,COG0030@1,COG0030@2 NA|NA|NA J Methyltransferase gnl|extdb|FAM14217-p1-1.1_000104 754252.PFREUD_02130 5.1e-284 983.0 Actinobacteria aroP GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008104,GO:0008150,GO:0008320,GO:0008324,GO:0008509,GO:0008514,GO:0008565,GO:0009977,GO:0015031,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015291,GO:0015318,GO:0015399,GO:0015405,GO:0015450,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015833,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1904680,GO:1905039 ko:K03293,ko:K11732,ko:K11734 ko00000,ko02000 2.A.3.1,2.A.3.1.1,2.A.3.1.3 iAPECO1_1312.APECO1_1472,iECW_1372.ECW_m0628,iEcE24377_1341.EcE24377A_0114,iEcolC_1368.EcolC_3070,iJN746.PP_4495,iUTI89_1310.UTI89_C0576,iWFL_1372.ECW_m0628 Bacteria 2GJ0X@201174,COG1113@1,COG1113@2 NA|NA|NA E amino acid gnl|extdb|FAM14217-p1-1.1_000105 754252.PFREUD_02120 3.8e-162 577.4 Propionibacteriales folP2 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJNI@201174,4DNDN@85009,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives gnl|extdb|FAM14217-p1-1.1_000107 754252.PFREUD_02100 1.9e-303 1047.7 Propionibacteriales ycfI GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4DNTU@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM14217-p1-1.1_000108 754252.PFREUD_02090 0.0 1242.6 Propionibacteriales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4DN2U@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM14217-p1-1.1_000109 754252.PFREUD_02080 1.2e-163 582.4 Bacteria ko:K02529 ko00000,ko03000 Bacteria COG4977@1,COG4977@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM14217-p1-1.1_000110 754252.PFREUD_02070 1.8e-114 418.7 Propionibacteriales Bacteria 2I234@201174,4DVRZ@85009,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family gnl|extdb|FAM14217-p1-1.1_000111 754252.PFREUD_02060 3e-75 287.7 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM14217-p1-1.1_000112 754252.PFREUD_02050 7.8e-100 369.8 Propionibacteriales ko:K03088 ko00000,ko03021 Bacteria 2HG3D@201174,4DRTW@85009,COG1595@1,COG1595@2 NA|NA|NA K ECF sigma factor gnl|extdb|FAM14217-p1-1.1_000114 754252.PFREUD_02030 9.3e-77 292.7 Actinobacteria ko:K07071 ko00000 Bacteria 2ISSK@201174,COG4276@1,COG4276@2 NA|NA|NA S Ketosteroid isomerase-related protein gnl|extdb|FAM14217-p1-1.1_000116 754252.PFREUD_02010 2.2e-66 258.1 Actinobacteria Bacteria 291AJ@1,2HBY6@201174,2ZNXJ@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000118 754252.PFREUD_01980 7.1e-112 409.8 Actinobacteria Bacteria 2H5TR@201174,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase gnl|extdb|FAM14217-p1-1.1_000119 754252.PFREUD_01970 4.3e-247 860.1 Propionibacteriales Bacteria 2GN3K@201174,4DPZD@85009,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family gnl|extdb|FAM14217-p1-1.1_000120 68199.JNZO01000026_gene5687 2.5e-10 72.4 Actinobacteria Bacteria 2GQHQ@201174,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM14217-p1-1.1_000121 754252.PFREUD_01940 2e-236 824.7 Propionibacteriales Bacteria 2GMMI@201174,4DRVY@85009,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain gnl|extdb|FAM14217-p1-1.1_000122 754252.PFREUD_01930 1e-181 642.5 Actinobacteria Bacteria 2D089@1,2IHKJ@201174,32T81@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system gnl|extdb|FAM14217-p1-1.1_000123 754252.PFREUD_01920 2.2e-108 398.3 Propionibacteriales Bacteria 2IM3H@201174,4DWAS@85009,COG5340@1,COG5340@2 NA|NA|NA K Transcriptional regulator, AbiEi antitoxin gnl|extdb|FAM14217-p1-1.1_000130 754252.PFREUD_01830 5.9e-302 1042.7 Propionibacteriales preT Bacteria 2GJ0A@201174,4DU0U@85009,COG0493@1,COG0493@2 NA|NA|NA C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gnl|extdb|FAM14217-p1-1.1_000131 754252.PFREUD_01810 1.5e-52 211.8 Propionibacteriales GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2IQ7E@201174,4DR5J@85009,COG0011@1,COG0011@2 NA|NA|NA S Thiamine-binding protein gnl|extdb|FAM14217-p1-1.1_000132 754252.PFREUD_01800 4.2e-86 323.9 Actinobacteria Bacteria 2GRWW@201174,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator TetR gnl|extdb|FAM14217-p1-1.1_000134 754252.PFREUD_24430 8.8e-170 603.2 Propionibacteriales ko:K07497 ko00000 Bacteria 2IDYA@201174,4DWSB@85009,COG2801@1,COG2801@2 NA|NA|NA L 4.4 Phage-related function gnl|extdb|FAM14217-p1-1.1_000135 754252.PFREUD_01780 2.4e-261 907.9 Propionibacteriales Bacteria 2GIZX@201174,4DPB8@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000136 754252.PFREUD_01750 7.5e-182 643.3 Propionibacteriales argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8IJ@201174,4DPX4@85009,COG0624@1,COG0624@2 NA|NA|NA E Acetylornithine deacetylase gnl|extdb|FAM14217-p1-1.1_000137 754252.PFREUD_01740 0.0 2100.5 Propionibacteriales cydC ko:K06148,ko:K16012,ko:K16013,ko:K16014 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1,3.A.1.129 Bacteria 2I2DP@201174,4DP3V@85009,COG4987@1,COG4987@2,COG4988@1,COG4988@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM14217-p1-1.1_000138 754252.PFREUD_01730 1.8e-212 745.0 Propionibacteriales cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120 Bacteria 2GMFV@201174,4DN35@85009,COG1294@1,COG1294@2 NA|NA|NA C oxidase, subunit gnl|extdb|FAM14217-p1-1.1_000139 754252.PFREUD_01720 2.9e-287 993.8 Propionibacteriales cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 2GJE4@201174,4DNI9@85009,COG1271@1,COG1271@2 NA|NA|NA C Cytochrome bd terminal oxidase subunit I gnl|extdb|FAM14217-p1-1.1_000140 754252.PFREUD_01710 2.2e-113 414.8 Actinobacteria 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJZ0@201174,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III gnl|extdb|FAM14217-p1-1.1_000142 754252.PFREUD_01690 1.1e-65 255.8 Propionibacteriales fkbP 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2IHQC@201174,4DQUT@85009,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans gnl|extdb|FAM14217-p1-1.1_000143 754252.PFREUD_01680 1.1e-39 168.7 Propionibacteriales yjdI 1.6.3.4 ko:K07397,ko:K22405 ko00000,ko01000 Bacteria 2II8Q@201174,4DS90@85009,COG3592@1,COG3592@2 NA|NA|NA S Divergent 4Fe-4S mono-cluster gnl|extdb|FAM14217-p1-1.1_000145 754252.PFREUD_01660 5.1e-110 403.7 Propionibacteriales yiiE Bacteria 2IGXY@201174,4DUV8@85009,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) gnl|extdb|FAM14217-p1-1.1_000146 754252.PFREUD_01650 9e-107 392.9 Actinobacteria ylcC 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2INDK@201174,COG3764@1,COG3764@2 NA|NA|NA M Sortase (surface protein transpeptidase) gnl|extdb|FAM14217-p1-1.1_000148 754252.PFREUD_01630 3.1e-119 434.5 Propionibacteriales Bacteria 2GJ46@201174,4DQC2@85009,COG2197@1,COG2197@2 NA|NA|NA T response regulator gnl|extdb|FAM14217-p1-1.1_000149 754252.PFREUD_01620 3.9e-159 567.4 Propionibacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4DNEX@85009,COG1136@1,COG1136@2 NA|NA|NA V COG1136 ABC-type antimicrobial peptide transport system, ATPase component gnl|extdb|FAM14217-p1-1.1_000150 754252.PFREUD_01610 0.0 1402.1 Propionibacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2H37M@201174,4DWWD@85009,COG3127@1,COG3127@2 NA|NA|NA Q FtsX-like permease family gnl|extdb|FAM14217-p1-1.1_000152 754252.PFREUD_01590 1.3e-206 725.3 Bacteria 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria COG2706@1,COG2706@2 NA|NA|NA G 6-phosphogluconolactonase activity gnl|extdb|FAM14217-p1-1.1_000153 754252.PFREUD_01580 2.9e-148 531.2 Propionibacteriales aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2552c Bacteria 2GPQQ@201174,4DQSP@85009,COG0169@1,COG0169@2 NA|NA|NA E Shikimate dehydrogenase substrate binding domain gnl|extdb|FAM14217-p1-1.1_000154 754252.PFREUD_01570 2.2e-131 474.9 Propionibacteriales glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2GNM5@201174,4DRS8@85009,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase gnl|extdb|FAM14217-p1-1.1_000155 754252.PFREUD_01560 2.7e-123 448.0 Propionibacteriales Bacteria 2GKK7@201174,4DRYB@85009,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM14217-p1-1.1_000156 754252.PFREUD_01550 1.5e-168 599.0 Actinobacteria Bacteria 2H595@201174,COG4767@1,COG4767@2 NA|NA|NA V Glycopeptide antibiotics resistance protein gnl|extdb|FAM14217-p1-1.1_000160 754252.PFREUD_01500 0.0 1253.8 Propionibacteriales Bacteria 2GM55@201174,4DPV3@85009,COG1316@1,COG1316@2 NA|NA|NA K cell envelope-related transcriptional attenuator gnl|extdb|FAM14217-p1-1.1_000161 754252.PFREUD_24640 8.6e-234 815.8 Propionibacteriales yagA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07497 ko00000 Bacteria 2GJ3V@201174,4DSTQ@85009,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L Homeodomain-like domain gnl|extdb|FAM14217-p1-1.1_000164 754252.PFREUD_01470 2.9e-179 634.4 Propionibacteriales qor 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 2GN47@201174,4DNH8@85009,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase gnl|extdb|FAM14217-p1-1.1_000165 754252.PFREUD_01460 7.5e-277 959.1 Propionibacteriales argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iSBO_1134.SBO_3210,iSbBS512_1146.SbBS512_E3599 Bacteria 2GK96@201174,4DNHA@85009,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 2 subfamily gnl|extdb|FAM14217-p1-1.1_000167 754252.PFREUD_01440 6.9e-141 506.5 Propionibacteriales cobB ko:K12410 ko00000,ko01000 Bacteria 2IJ46@201174,4DQQ7@85009,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form gnl|extdb|FAM14217-p1-1.1_000168 754252.PFREUD_01430 2.1e-85 321.6 Propionibacteriales tpx 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 2II20@201174,4DQU5@85009,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides gnl|extdb|FAM14217-p1-1.1_000169 754252.PFREUD_01420 5e-95 354.0 Actinobacteria Bacteria 2DBY6@1,2IM2N@201174,2ZBTG@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000170 754252.PFREUD_01410 8.4e-183 646.4 Propionibacteriales Bacteria 2GIX7@201174,4DP74@85009,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain gnl|extdb|FAM14217-p1-1.1_000172 754252.PFREUD_01390 2.1e-271 941.0 Propionibacteriales ko:K07576 ko00000 Bacteria 2HEXB@201174,4DQ4R@85009,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain gnl|extdb|FAM14217-p1-1.1_000174 926564.KI911686_gene5458 1.2e-25 123.6 Actinobacteria Bacteria 2AD8S@1,2I87J@201174,312XT@2 NA|NA|NA S Golgi phosphoprotein 3 (GPP34) gnl|extdb|FAM14217-p1-1.1_000175 754252.PFREUD_01350 7e-234 816.2 Propionibacteriales serS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIWP@201174,4DNQN@85009,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) gnl|extdb|FAM14217-p1-1.1_000176 754252.PFREUD_01340 1.4e-145 522.7 Propionibacteriales 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJ3K@201174,4DNXQ@85009,COG0671@1,COG0671@2,COG1597@1,COG1597@2 NA|NA|NA I diacylglycerol kinase gnl|extdb|FAM14217-p1-1.1_000177 754252.PFREUD_01330 6.3e-182 643.3 Propionibacteriales pheA 1.3.1.12,4.2.1.51,5.4.99.5 ko:K04517,ko:K04518,ko:K14170 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQ5@201174,4DN8Z@85009,COG0077@1,COG0077@2 NA|NA|NA E Prephenate dehydratase gnl|extdb|FAM14217-p1-1.1_000178 469371.Tbis_1699 7e-07 61.2 Actinobacteria Bacteria 2E89B@1,2IMU0@201174,332N6@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000179 754252.PFREUD_01310 6.9e-186 656.4 Actinobacteria styA 2.6.1.42,3.2.1.21 ko:K00826,ko:K05349 ko00270,ko00280,ko00290,ko00460,ko00500,ko00770,ko00940,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00460,map00500,map00770,map00940,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R00026,R01090,R01214,R02199,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040,R10991 RC00006,RC00036,RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000,ko01007 GH3 Bacteria 2IAFA@201174,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase gnl|extdb|FAM14217-p1-1.1_000180 754252.PFREUD_01300 1.5e-308 1064.7 Propionibacteriales pabB 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJT@201174,4DPGT@85009,COG0147@1,COG0147@2 NA|NA|NA EH chorismate binding enzyme gnl|extdb|FAM14217-p1-1.1_000181 754252.PFREUD_01290 4.8e-190 670.2 Bacteria panE1 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria COG1893@1,COG1893@2 NA|NA|NA H 2-dehydropantoate 2-reductase activity gnl|extdb|FAM14217-p1-1.1_000182 754252.PFREUD_01280 1.2e-166 592.8 Propionibacteriales ybhS ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2HEJT@201174,4DQ1W@85009,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein gnl|extdb|FAM14217-p1-1.1_000184 754252.PFREUD_01260 1.5e-299 1034.6 Propionibacteriales hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GKAQ@201174,4DTIH@85009,COG0286@1,COG0286@2 NA|NA|NA V HsdM N-terminal domain gnl|extdb|FAM14217-p1-1.1_000185 471853.Bcav_0504 7e-87 327.8 Actinobacteria hsdS2 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 2IAIR@201174,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain gnl|extdb|FAM14217-p1-1.1_000186 1203568.HMPREF1484_01822 0.0 1266.9 Dermabacteraceae hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2HI69@201174,4FDXM@85020,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification gnl|extdb|FAM14217-p1-1.1_000188 754252.PFREUD_01210 6.3e-187 659.8 Propionibacteriales ymdB Bacteria 2IFEC@201174,4DQSG@85009,COG2110@1,COG2110@2 NA|NA|NA S Appr-1'-p processing enzyme gnl|extdb|FAM14217-p1-1.1_000191 754252.PFREUD_01040 1.2e-296 1025.0 Propionibacteriales 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 R01737 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2IAKI@201174,4DTR5@85009,COG1070@1,COG1070@2 NA|NA|NA G FGGY family of carbohydrate kinases, N-terminal domain gnl|extdb|FAM14217-p1-1.1_000192 754252.PFREUD_01050 1.4e-161 575.5 Propionibacteriales fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKAM@201174,4DN9T@85009,COG0266@1,COG0266@2 NA|NA|NA L Belongs to the FPG family gnl|extdb|FAM14217-p1-1.1_000193 754252.PFREUD_01060 4.7e-142 510.4 Propionibacteriales aat 2.3.2.6 ko:K00684 R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 Bacteria 2IFT7@201174,4DQD7@85009,COG2360@1,COG2360@2 NA|NA|NA O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine gnl|extdb|FAM14217-p1-1.1_000194 754252.PFREUD_01070 9.8e-181 640.6 Actinobacteria Bacteria 2GM6E@201174,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM14217-p1-1.1_000195 754252.PFREUD_01080 1.4e-67 262.7 Actinobacteria rpfA ko:K21687 ko00000 GH23 Bacteria 2GQ1M@201174,COG1388@1,COG1388@2 NA|NA|NA M Transglycosylase-like domain gnl|extdb|FAM14217-p1-1.1_000196 754252.PFREUD_01090 5.5e-250 869.8 Propionibacteriales gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GSH4@201174,4DWPV@85009,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain gnl|extdb|FAM14217-p1-1.1_000197 754252.PFREUD_01100 7.5e-141 506.5 Propionibacteriales Bacteria 28MIG@1,2IGFB@201174,2ZAV8@2,4DQAF@85009 NA|NA|NA S EcsC protein family gnl|extdb|FAM14217-p1-1.1_000199 754252.PFREUD_01120 4.3e-281 973.4 Actinobacteria ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 2GMBS@201174,COG1404@1,COG1404@2 NA|NA|NA O cog cog1404 gnl|extdb|FAM14217-p1-1.1_000200 754252.PFREUD_01130 1.9e-214 751.5 Propionibacteriales alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 2GM2Y@201174,4DNHM@85009,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids gnl|extdb|FAM14217-p1-1.1_000203 754252.PFREUD_01150 1.2e-55 222.2 Bacteria arsR1 ko:K03892 ko00000,ko03000 Bacteria COG0640@1,COG0640@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM14217-p1-1.1_000204 762963.HMPREF9056_02856 6e-56 224.2 Actinobacteria Bacteria 2GK8E@201174,4D53J@85005,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family gnl|extdb|FAM14217-p1-1.1_000205 754252.PFREUD_24230 3.2e-258 897.1 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000207 754252.PFREUD_00760 6.2e-301 1039.3 Actinobacteria 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNCR@201174,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family gnl|extdb|FAM14217-p1-1.1_000208 754252.PFREUD_00770 2.5e-192 677.9 Actinobacteria gpsA 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJSD@201174,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase gnl|extdb|FAM14217-p1-1.1_000209 754252.PFREUD_00780 1.1e-136 492.7 Actinobacteria Bacteria 2I8G0@201174,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain gnl|extdb|FAM14217-p1-1.1_000210 754252.PFREUD_00790 6.8e-192 676.4 Propionibacteriales 3.2.2.21 ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GP69@201174,4DPY4@85009,COG0122@1,COG0122@2 NA|NA|NA L 3-methyladenine DNA glycosylase gnl|extdb|FAM14217-p1-1.1_000213 754252.PFREUD_00820 1.5e-126 458.8 Propionibacteriales Bacteria 2GIZB@201174,4DP6U@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM14217-p1-1.1_000214 754252.PFREUD_00830 1.9e-140 505.4 Propionibacteriales 3.4.13.21,3.4.15.6 ko:K05995,ko:K13282 R09722 RC00064,RC00141 ko00000,ko01000,ko01002 Bacteria 2IG1C@201174,4DSB5@85009,COG4242@1,COG4242@2 NA|NA|NA PQ Belongs to the peptidase S51 family gnl|extdb|FAM14217-p1-1.1_000215 754252.PFREUD_00840 8.2e-84 316.2 Propionibacteriales ptpA GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 2IM0Q@201174,4DR9C@85009,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family gnl|extdb|FAM14217-p1-1.1_000216 754252.PFREUD_00850 8e-61 239.6 Bacteria yvlD ko:K08972 ko00000 Bacteria COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV gnl|extdb|FAM14217-p1-1.1_000217 754252.PFREUD_00860 4.1e-189 667.2 Propionibacteriales argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 iAF1260.b0273,iECDH10B_1368.ECDH10B_0261,iECS88_1305.ECS88_4841,iHN637.CLJU_RS12430,iJO1366.b0273,iJR904.b0273,iY75_1357.Y75_RS01410 Bacteria 2GJ6H@201174,4DPPU@85009,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline gnl|extdb|FAM14217-p1-1.1_000218 754252.PFREUD_00870 2.1e-111 408.3 Propionibacteriales mug GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.28,6.3.3.2 ko:K01934,ko:K03649 ko00670,ko01100,ko03410,map00670,map01100,map03410 R02301 RC00183 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNS5@201174,4DQD9@85009,COG3663@1,COG3663@2 NA|NA|NA L Uracil DNA glycosylase superfamily gnl|extdb|FAM14217-p1-1.1_000219 754252.PFREUD_00880 1.2e-148 532.3 Propionibacteriales Bacteria 2GK8E@201174,4DPW6@85009,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family gnl|extdb|FAM14217-p1-1.1_000220 754252.PFREUD_24270 7.1e-269 932.6 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000221 1232429.CBLL010000159_gene654 1.4e-13 82.0 Micrococcaceae Bacteria 1WCFW@1268,2I2PD@201174,COG4227@1,COG4227@2 NA|NA|NA L Pfam:DUF955 gnl|extdb|FAM14217-p1-1.1_000222 754252.PFREUD_00900 6.9e-190 669.8 Propionibacteriales rbn ko:K03466,ko:K07058 ko00000,ko03036 3.A.12 Bacteria 2GM6P@201174,4DP5Z@85009,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB gnl|extdb|FAM14217-p1-1.1_000223 754252.PFREUD_00910 1.1e-58 233.0 Propionibacteriales Bacteria 2B9CE@1,2IKT2@201174,322Q4@2,4DRJ3@85009 NA|NA|NA S Protein of unknown function (DUF3618) gnl|extdb|FAM14217-p1-1.1_000225 754252.PFREUD_00930 3.3e-203 714.1 Actinobacteria Bacteria 2DGZY@1,2HDJM@201174,2ZXX0@2 NA|NA|NA S function, without similarity to other proteins gnl|extdb|FAM14217-p1-1.1_000226 754252.PFREUD_01040 1.8e-21 109.0 Propionibacteriales 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 R01737 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2IAKI@201174,4DTR5@85009,COG1070@1,COG1070@2 NA|NA|NA G FGGY family of carbohydrate kinases, N-terminal domain gnl|extdb|FAM14217-p1-1.1_000227 754252.PFREUD_00960 2e-119 435.3 Propionibacteriales hflC Bacteria 2GKFP@201174,4DTAB@85009,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues gnl|extdb|FAM14217-p1-1.1_000229 754252.PFREUD_00980 0.0 1518.4 Actinobacteria norZ 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 Bacteria 2I6ZN@201174,COG3256@1,COG3256@2 NA|NA|NA P nitric oxide reductase gnl|extdb|FAM14217-p1-1.1_000231 754252.PFREUD_01070 4.8e-09 66.6 Actinobacteria Bacteria 2GM6E@201174,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM14217-p1-1.1_000232 754252.PFREUD_24290 3.8e-173 614.4 Propionibacteriales ko:K07497 ko00000 Bacteria 2IDYA@201174,4DWSB@85009,COG2801@1,COG2801@2 NA|NA|NA L 4.4 Phage-related function gnl|extdb|FAM14217-p1-1.1_000233 1170318.PALO_00230 2.7e-36 157.9 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000234 754252.PFREUD_24530 3e-42 177.6 Propionibacteriales Bacteria 2GJK7@201174,4DTG9@85009,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000235 754252.PFREUD_24230 3.2e-258 897.1 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000236 754252.PFREUD_25130 9.9e-260 902.1 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000239 754252.PFREUD_23130 2.1e-173 614.8 Propionibacteriales iolH ko:K06605 ko00000 Bacteria 2GMU1@201174,4DVPQ@85009,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel gnl|extdb|FAM14217-p1-1.1_000240 754252.PFREUD_23140 6.8e-187 659.8 Bacteria ko:K02529 ko00000,ko03000 Bacteria COG1609@1,COG1609@2 NA|NA|NA K purine nucleotide biosynthetic process gnl|extdb|FAM14217-p1-1.1_000242 754252.PFREUD_23150 1.4e-183 648.7 Actinobacteria 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Bacteria 2GPA8@201174,COG2267@1,COG2267@2 NA|NA|NA I hydrolase gnl|extdb|FAM14217-p1-1.1_000243 754252.PFREUD_23160 2.4e-141 508.1 Propionibacteriales ugpQ GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008889,GO:0016787,GO:0016788,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0047389,GO:0047395 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 iEC042_1314.EC042_3710,iEC55989_1330.EC55989_3857 Bacteria 2GNM5@201174,4DQNY@85009,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family gnl|extdb|FAM14217-p1-1.1_000244 754252.PFREUD_23170 3.5e-239 833.9 Actinobacteria Bacteria 2I5AK@201174,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000245 754252.PFREUD_23180 1.8e-133 481.9 Actinobacteria sidE ko:K04756,ko:K14698 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.21.2 Bacteria 2GP41@201174,COG2375@1,COG2375@2 NA|NA|NA P siderophore-interacting protein gnl|extdb|FAM14217-p1-1.1_000247 754252.PFREUD_23200 4.1e-220 770.4 Propionibacteriales Bacteria 2GK0F@201174,4DPFS@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM14217-p1-1.1_000248 754252.PFREUD_23210 1.4e-187 662.1 Propionibacteriales lacI4 ko:K02529 ko00000,ko03000 Bacteria 2GMUU@201174,4DNP6@85009,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain gnl|extdb|FAM14217-p1-1.1_000249 754252.PFREUD_23220 6.6e-161 573.2 Propionibacteriales sseB 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 Bacteria 2GMDR@201174,4DQ8V@85009,COG2897@1,COG2897@2 NA|NA|NA P Rhodanese Homology Domain gnl|extdb|FAM14217-p1-1.1_000250 754252.PFREUD_23230 1.3e-284 984.9 Propionibacteriales gadB 4.1.1.15 ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 M00027 R00261,R00489,R01682,R02466 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKIH@201174,4DPUT@85009,COG0076@1,COG0076@2 NA|NA|NA E Pyridoxal-dependent decarboxylase conserved domain gnl|extdb|FAM14217-p1-1.1_000251 754252.PFREUD_23240 4.7e-255 886.7 Actinobacteria gadC ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 2HMMA@201174,COG0531@1,COG0531@2 NA|NA|NA E amino acid gnl|extdb|FAM14217-p1-1.1_000252 754252.PFREUD_23250 0.0 1290.8 Actinobacteria Bacteria 2I8QF@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000254 754252.PFREUD_23280 3.6e-154 550.8 Propionibacteriales Bacteria 2GIYQ@201174,4DS0X@85009,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain gnl|extdb|FAM14217-p1-1.1_000256 754252.PFREUD_23300 2.3e-170 604.7 Propionibacteriales proV ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iNJ661.Rv3758c Bacteria 2GJHI@201174,4DPZM@85009,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter gnl|extdb|FAM14217-p1-1.1_000257 754252.PFREUD_23310 1.5e-104 385.6 Propionibacteriales proW ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GMU0@201174,4DQQZ@85009,COG1174@1,COG1174@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000258 754252.PFREUD_23320 3.3e-97 361.3 Actinobacteria proZ ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GYTC@201174,COG1174@1,COG1174@2 NA|NA|NA E ABC transporter (Permease) gnl|extdb|FAM14217-p1-1.1_000259 754252.PFREUD_23330 3.3e-230 803.9 Propionibacteriales ko:K10907 ko00000,ko01000,ko01007 Bacteria 2GJ7R@201174,4DN5T@85009,COG0436@1,COG0436@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme gnl|extdb|FAM14217-p1-1.1_000261 754252.PFREUD_23350 1.1e-46 192.2 Bacteria Bacteria COG3797@1,COG3797@2 NA|NA|NA S Protein of unknown function (DUF1697) gnl|extdb|FAM14217-p1-1.1_000263 1306174.JODP01000016_gene7165 4.7e-51 208.4 Actinobacteria MA20_25180 Bacteria 2GK06@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000264 1449355.JQNR01000003_gene107 4.2e-07 60.1 Actinobacteria MA20_25180 Bacteria 2GK06@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000267 754252.PFREUD_23410 3.3e-175 620.9 Actinobacteria ugpE ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 2GMTH@201174,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter (Permease) gnl|extdb|FAM14217-p1-1.1_000268 754252.PFREUD_23420 1.5e-253 881.7 Bacteria ugpB ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria COG1653@1,COG1653@2 NA|NA|NA G carbohydrate transport gnl|extdb|FAM14217-p1-1.1_000270 754252.PFREUD_23440 7.3e-77 293.1 Propionibacteriales rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKX7@201174,4DQYG@85009,COG0359@1,COG0359@2 NA|NA|NA J binds to the 23S rRNA gnl|extdb|FAM14217-p1-1.1_000271 754252.PFREUD_23450 6.2e-35 152.9 Propionibacteriales rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 2IQ92@201174,4DRVS@85009,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit gnl|extdb|FAM14217-p1-1.1_000272 754252.PFREUD_23460 1e-75 289.7 Propionibacteriales ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GMM3@201174,4DQ95@85009,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein gnl|extdb|FAM14217-p1-1.1_000275 754252.PFREUD_23500 2.1e-63 248.1 Bacteria 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria COG0221@1,COG0221@2 NA|NA|NA C inorganic diphosphatase activity gnl|extdb|FAM14217-p1-1.1_000276 754252.PFREUD_23510 1.3e-130 472.2 Propionibacteriales hemH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK24@201174,4DP69@85009,COG3253@1,COG3253@2 NA|NA|NA S Chlorite dismutase gnl|extdb|FAM14217-p1-1.1_000277 754252.PFREUD_23520 5.4e-65 253.4 Actinobacteria 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 R07459,R07461 RC00043 ko00000,ko00001,ko01000 Bacteria 2IH0R@201174,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain gnl|extdb|FAM14217-p1-1.1_000278 754252.PFREUD_23530 5.8e-124 450.3 Bacteria 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria COG1335@1,COG1335@2 NA|NA|NA Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides gnl|extdb|FAM14217-p1-1.1_000280 1122138.AQUZ01000008_gene3765 1.5e-191 675.6 Propionibacteriales Bacteria 2GJK7@201174,4DTG9@85009,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000281 754252.PFREUD_23820 0.0 1169.5 Propionibacteriales ubiB ko:K03688 ko00000 Bacteria 2GJQ6@201174,4DQX3@85009,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family gnl|extdb|FAM14217-p1-1.1_000282 754252.PFREUD_23810 5.3e-175 620.2 Actinobacteria dyp ko:K07223 ko00000 Bacteria 2GMNJ@201174,COG2837@1,COG2837@2 NA|NA|NA P peroxidase gnl|extdb|FAM14217-p1-1.1_000283 754252.PFREUD_23800 3e-289 1000.3 Propionibacteriales katA 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 Bacteria 2GITN@201174,4DP8F@85009,COG0753@1,COG0753@2 NA|NA|NA P Serves to protect cells from the toxic effects of hydrogen peroxide gnl|extdb|FAM14217-p1-1.1_000284 754252.PFREUD_23790 1.8e-56 224.9 Bacteria Bacteria 2AU69@1,31JT7@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000285 754252.PFREUD_23780 0.0 1142.1 Propionibacteriales 6.2.1.3,6.2.1.31 ko:K00666,ko:K01897,ko:K16876 ko00061,ko00071,ko00365,ko01100,ko01120,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00365,map01100,map01120,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R02986 RC00004,RC00014,RC00174 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIUC@201174,4DWKQ@85009,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme gnl|extdb|FAM14217-p1-1.1_000286 754252.PFREUD_23770 1.3e-182 645.6 Bacteria Bacteria COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity gnl|extdb|FAM14217-p1-1.1_000287 754252.PFREUD_23760 0.0 1187.2 Propionibacteriales pbuX 4.1.1.97 ko:K03458,ko:K13485 ko00230,ko01100,map00230,map01100 M00546 R06604 RC01551 ko00000,ko00001,ko00002,ko01000 2.A.40 Bacteria 2GMH6@201174,4DN54@85009,COG2233@1,COG2233@2,COG3195@1,COG3195@2 NA|NA|NA F Permease family gnl|extdb|FAM14217-p1-1.1_000289 754252.PFREUD_23740 0.0 1227.6 Propionibacteriales aglA 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4DNRU@85009,COG0366@1,COG0366@2 NA|NA|NA G SMART alpha amylase, catalytic sub domain gnl|extdb|FAM14217-p1-1.1_000291 754252.PFREUD_23720 4.8e-162 577.0 Actinobacteria morA2 Bacteria 2GJQ7@201174,COG0656@1,COG0656@2 NA|NA|NA K aldo keto reductase gnl|extdb|FAM14217-p1-1.1_000292 754252.PFREUD_23710 1.4e-231 808.5 Actinobacteria eryK Bacteria 2IJFZ@201174,COG2124@1,COG2124@2 NA|NA|NA C Cytochrome P450 gnl|extdb|FAM14217-p1-1.1_000294 754252.PFREUD_23690 9e-153 546.2 Actinobacteria Bacteria 2GJPB@201174,COG4292@1,COG4292@2 NA|NA|NA S Low temperature requirement gnl|extdb|FAM14217-p1-1.1_000295 1448139.AI20_13930 2.3e-52 213.8 Gammaproteobacteria Bacteria 1R33M@1224,1T62P@1236,COG1384@1,COG1384@2,COG3454@1,COG3454@2 NA|NA|NA J Domain of unknown function (DUF4209) gnl|extdb|FAM14217-p1-1.1_000298 754252.PFREUD_23650 3e-77 294.3 Actinobacteria Bacteria 2CQNK@1,2IIJ7@201174,32SMG@2 NA|NA|NA S Family of unknown function (DUF5318) gnl|extdb|FAM14217-p1-1.1_000299 754252.PFREUD_23640 0.0 1253.8 Propionibacteriales mrcB 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4DMYZ@85009,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase gnl|extdb|FAM14217-p1-1.1_000300 754252.PFREUD_23630 8.2e-291 1005.7 Propionibacteriales Bacteria 2GJYA@201174,4DPN0@85009,COG5650@1,COG5650@2 NA|NA|NA S integral membrane protein gnl|extdb|FAM14217-p1-1.1_000301 754252.PFREUD_23620 7.8e-208 729.6 Propionibacteriales Bacteria 2HZNP@201174,4DTDM@85009,COG5542@1,COG5542@2 NA|NA|NA S integral membrane protein gnl|extdb|FAM14217-p1-1.1_000303 754252.PFREUD_23600 9.6e-233 812.4 Propionibacteriales rtcB 6.5.1.3 ko:K14415 ko00000,ko01000,ko03016 Bacteria 2GIUP@201174,4DPPZ@85009,COG1690@1,COG1690@2 NA|NA|NA S tRNA-splicing ligase RtcB gnl|extdb|FAM14217-p1-1.1_000304 754252.PFREUD_23590 4.2e-115 420.6 Propionibacteriales tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IFH0@201174,4DQTX@85009,COG2818@1,COG2818@2 NA|NA|NA L Methyladenine glycosylase gnl|extdb|FAM14217-p1-1.1_000305 754252.PFREUD_23580 3.5e-222 777.3 Propionibacteriales Bacteria 2GK1K@201174,4DTNQ@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000306 754252.PFREUD_03310 2e-67 264.2 Bacteria Bacteria COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family gnl|extdb|FAM14217-p1-1.1_000307 1122138.AQUZ01000008_gene3765 1.5e-191 675.6 Propionibacteriales Bacteria 2GJK7@201174,4DTG9@85009,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000308 754252.PFREUD_24640 8.6e-234 815.8 Propionibacteriales yagA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07497 ko00000 Bacteria 2GJ3V@201174,4DSTQ@85009,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L Homeodomain-like domain gnl|extdb|FAM14217-p1-1.1_000310 754252.PFREUD_23840 1.1e-223 782.3 Actinobacteria clcA_2 ko:K03281 ko00000 2.A.49 Bacteria 2GPPN@201174,COG0038@1,COG0038@2 NA|NA|NA P Chloride channel gnl|extdb|FAM14217-p1-1.1_000314 754252.PFREUD_23890 1.7e-162 578.6 Actinobacteria fda 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 Bacteria 2GN1A@201174,COG3588@1,COG3588@2 NA|NA|NA G Aldolase gnl|extdb|FAM14217-p1-1.1_000315 754252.PFREUD_23900 4.5e-97 360.5 Propionibacteriales yceI Bacteria 2GJUB@201174,4DQQD@85009,COG2353@1,COG2353@2 NA|NA|NA S Belongs to the UPF0312 family gnl|extdb|FAM14217-p1-1.1_000316 754252.PFREUD_23910 1.2e-246 858.6 Propionibacteriales gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ7E@201174,4DPEX@85009,COG0372@1,COG0372@2 NA|NA|NA C Belongs to the citrate synthase family gnl|extdb|FAM14217-p1-1.1_000318 754252.PFREUD_23930 7.5e-116 423.3 Propionibacteriales Bacteria 2IIVD@201174,4DQSM@85009,COG4291@1,COG4291@2 NA|NA|NA S Protein of unknown function (DUF1345) gnl|extdb|FAM14217-p1-1.1_000320 754252.PFREUD_23950 0.0 1274.6 Propionibacteriales ko:K01992,ko:K06994 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJ5A@201174,4DP70@85009,COG1511@1,COG1511@2,COG2409@1,COG2409@2 NA|NA|NA P MMPL family gnl|extdb|FAM14217-p1-1.1_000321 754252.PFREUD_23960 2.2e-125 454.9 Actinobacteria Bacteria 2GJQY@201174,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000322 754252.PFREUD_23970 4.2e-118 430.6 Actinobacteria Bacteria 2IC5H@201174,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding gnl|extdb|FAM14217-p1-1.1_000324 754252.PFREUD_23990 4.8e-148 530.4 Bacteria 6.6.1.2 ko:K02230 ko00860,ko01100,map00860,map01100 R05227 RC02000 ko00000,ko00001,ko01000 Bacteria COG3411@1,COG3411@2 NA|NA|NA C Ferredoxin gnl|extdb|FAM14217-p1-1.1_000325 754252.PFREUD_24000 3.3e-127 461.1 Propionibacteriales 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 2IJ6H@201174,4DWKM@85009,COG1120@1,COG1120@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_000326 754252.PFREUD_24010 6e-181 640.2 Propionibacteriales ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GK8Z@201174,4DN77@85009,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM14217-p1-1.1_000327 754252.PFREUD_24020 1.1e-163 582.8 Propionibacteriales ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GKZJ@201174,4DPXR@85009,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein gnl|extdb|FAM14217-p1-1.1_000328 754252.PFREUD_24030 3.6e-244 850.9 Propionibacteriales ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 2GMFK@201174,4DNMY@85009,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel gnl|extdb|FAM14217-p1-1.1_000329 754252.PFREUD_24040 3.4e-288 996.9 Propionibacteriales cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2GMT1@201174,4DMZV@85009,COG0617@1,COG0617@2 NA|NA|NA J Probable RNA and SrmB- binding site of polymerase A gnl|extdb|FAM14217-p1-1.1_000330 754252.PFREUD_24050 5.4e-270 936.4 Propionibacteriales hsrA_2 Bacteria 2H4H5@201174,4DWGG@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000332 1121933.AUHH01000007_gene3304 4.4e-34 152.9 Propionibacteriales Bacteria 2GN00@201174,4DQW4@85009,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV gnl|extdb|FAM14217-p1-1.1_000333 754252.PFREUD_24070 0.0 1160.2 Actinobacteria Bacteria 2GM4A@201174,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM14217-p1-1.1_000334 754252.PFREUD_24080 5.3e-138 496.9 Bacteria 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria COG0406@1,COG0406@2 NA|NA|NA G alpha-ribazole phosphatase activity gnl|extdb|FAM14217-p1-1.1_000335 754252.PFREUD_24090 9.8e-231 805.8 Actinobacteria malE ko:K02027,ko:K10188 ko02010,map02010 M00199,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.4 Bacteria 2GR9A@201174,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM14217-p1-1.1_000336 754252.PFREUD_24100 7.3e-183 646.4 Propionibacteriales trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K22345 ko00030,ko00450,map00030,map00450 R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000 iPC815.YPO1374 Bacteria 2GKD2@201174,4DPPP@85009,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family gnl|extdb|FAM14217-p1-1.1_000337 754252.PFREUD_24110 1.1e-55 222.2 Propionibacteriales trxA 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 2IQ9T@201174,4DRDT@85009,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family gnl|extdb|FAM14217-p1-1.1_000338 754252.PFREUD_24120 1.6e-76 292.0 Actinobacteria attW GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2IRWN@201174,COG1765@1,COG1765@2 NA|NA|NA O redox protein, regulator of disulfide bond formation gnl|extdb|FAM14217-p1-1.1_000339 754252.PFREUD_24140 6.5e-179 633.3 Propionibacteriales parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2GNRN@201174,4DNPD@85009,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family gnl|extdb|FAM14217-p1-1.1_000342 1122994.AUFR01000026_gene128 8.9e-64 250.8 Propionibacteriales jag ko:K06346,ko:K09749 ko00000 Bacteria 2GPZK@201174,4DQRW@85009,COG1847@1,COG1847@2 NA|NA|NA S Putative single-stranded nucleic acids-binding domain gnl|extdb|FAM14217-p1-1.1_000343 754252.PFREUD_24190 3.8e-178 630.9 Propionibacteriales yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2GJBU@201174,4DQ6T@85009,COG0706@1,COG0706@2 NA|NA|NA U 60Kd inner membrane protein gnl|extdb|FAM14217-p1-1.1_000344 754252.PFREUD_24200 7.9e-63 246.1 Propionibacteriales yidD ko:K08998 ko00000 Bacteria 2GQZG@201174,4DSGI@85009,COG0759@1,COG0759@2 NA|NA|NA S Could be involved in insertion of integral membrane proteins into the membrane gnl|extdb|FAM14217-p1-1.1_000345 754252.PFREUD_24210 1.8e-69 268.5 Propionibacteriales rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 2GR42@201174,4DSDD@85009,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme gnl|extdb|FAM14217-p1-1.1_000346 754252.PFREUD_24220 2.9e-13 80.1 Actinobacteria rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFY@201174,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family gnl|extdb|FAM14217-p1-1.1_000347 754252.PFREUD_00010 4.5e-269 933.3 Propionibacteriales dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2GJKI@201174,4DMZ1@85009,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids gnl|extdb|FAM14217-p1-1.1_000348 754252.PFREUD_00020 2.8e-258 897.5 Propionibacteriales Bacteria 2GIUM@201174,4DPZK@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000349 754252.PFREUD_00030 9.9e-109 399.4 Propionibacteriales Bacteria 2I9B3@201174,4DSCP@85009,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM14217-p1-1.1_000350 754252.PFREUD_00040 9.1e-220 769.2 Propionibacteriales sqdX Bacteria 2GIZG@201174,4DNSP@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM14217-p1-1.1_000351 754252.PFREUD_00050 6.2e-243 846.3 Actinobacteria sqdB 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 R05775 RC01469 ko00000,ko00001,ko01000 Bacteria 2GJJG@201174,COG0451@1,COG0451@2 NA|NA|NA GM Epimerase dehydratase gnl|extdb|FAM14217-p1-1.1_000353 754252.PFREUD_00070 0.0 1466.4 Propionibacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2H37M@201174,4DP5J@85009,COG3127@1,COG3127@2 NA|NA|NA Q MacB-like periplasmic core domain gnl|extdb|FAM14217-p1-1.1_000354 754252.PFREUD_00080 9.3e-209 732.6 Propionibacteriales dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJK3@201174,4DN43@85009,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria gnl|extdb|FAM14217-p1-1.1_000355 754252.PFREUD_00090 1.2e-236 825.5 Propionibacteriales recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJCS@201174,4DNK0@85009,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP gnl|extdb|FAM14217-p1-1.1_000357 754252.PFREUD_00110 0.0 1103.6 Bacteria Bacteria COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family gnl|extdb|FAM14217-p1-1.1_000360 754252.PFREUD_00530 7.6e-144 517.3 Propionibacteriales ko:K14340 ko00000,ko01000,ko01003 Bacteria 2I48D@201174,4DWG9@85009,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase gnl|extdb|FAM14217-p1-1.1_000362 754252.PFREUD_00520 8.3e-45 188.7 Bacteria welB Bacteria COG0463@1,COG0463@2,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase, family 2 gnl|extdb|FAM14217-p1-1.1_000363 754252.PFREUD_00520 2.7e-249 867.8 Bacteria welB Bacteria COG0463@1,COG0463@2,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase, family 2 gnl|extdb|FAM14217-p1-1.1_000364 754252.PFREUD_00500 3.7e-149 534.3 Actinobacteria Bacteria 2GMPV@201174,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 gnl|extdb|FAM14217-p1-1.1_000365 754252.PFREUD_00490 1.2e-42 179.5 Bacteria XK27_09090 ko:K09153 ko00000 Bacteria COG2456@1,COG2456@2 NA|NA|NA M Psort location CytoplasmicMembrane, score gnl|extdb|FAM14217-p1-1.1_000366 754252.PFREUD_00480 3.1e-128 464.5 Propionibacteriales ko:K00786 ko00000,ko01000 Bacteria 2GM44@201174,4DWXT@85009,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 gnl|extdb|FAM14217-p1-1.1_000367 754252.PFREUD_00470 1.3e-154 552.4 Propionibacteriales rfbA 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GP20@201174,4DNRQ@85009,COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis gnl|extdb|FAM14217-p1-1.1_000368 754252.PFREUD_00460 4.9e-240 837.4 Actinobacteria Bacteria 2HKW0@201174,COG5617@1,COG5617@2 NA|NA|NA S Psort location CytoplasmicMembrane, score gnl|extdb|FAM14217-p1-1.1_000369 754252.PFREUD_00460 5.6e-190 671.0 Actinobacteria Bacteria 2HKW0@201174,COG5617@1,COG5617@2 NA|NA|NA S Psort location CytoplasmicMembrane, score gnl|extdb|FAM14217-p1-1.1_000370 754252.PFREUD_00420 1.1e-78 299.3 Propionibacteriales tdsD Bacteria 2IHY1@201174,4DU3G@85009,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family gnl|extdb|FAM14217-p1-1.1_000371 754252.PFREUD_00410 5.2e-100 370.5 Propionibacteriales yigZ 2.1.1.45,3.4.13.9 ko:K00560,ko:K01271 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GMM4@201174,4DQWQ@85009,COG1739@1,COG1739@2 NA|NA|NA S Uncharacterized protein family UPF0029 gnl|extdb|FAM14217-p1-1.1_000372 1348338.ADILRU_2309 4.7e-27 127.1 Microbacteriaceae ko:K19159 ko00000,ko02048 Bacteria 2GSF2@201174,4FPZ6@85023,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin Phd_YefM, type II toxin-antitoxin system gnl|extdb|FAM14217-p1-1.1_000373 1122130.AUHN01000005_gene2443 1.1e-29 135.6 Actinobacteria ko:K06218 ko00000,ko02048 Bacteria 2IRES@201174,COG2026@1,COG2026@2 NA|NA|NA DJ ParE toxin of type II toxin-antitoxin system, parDE gnl|extdb|FAM14217-p1-1.1_000374 754252.PFREUD_00400 2.3e-44 184.5 Bacteria acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family gnl|extdb|FAM14217-p1-1.1_000375 754252.PFREUD_00390 2.8e-216 757.7 Propionibacteriales lppS GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0030312,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 Bacteria 2GJBA@201174,4DN7Y@85009,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain gnl|extdb|FAM14217-p1-1.1_000376 754252.PFREUD_00380 1.4e-284 984.9 Actinobacteria cycA ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 Bacteria 2GJ0X@201174,COG1113@1,COG1113@2 NA|NA|NA E amino acid gnl|extdb|FAM14217-p1-1.1_000377 754252.PFREUD_00370 2.9e-199 701.0 Propionibacteriales ald GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030312,GO:0036293,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 2GJ6G@201174,4DNSB@85009,COG0686@1,COG0686@2 NA|NA|NA E Belongs to the AlaDH PNT family gnl|extdb|FAM14217-p1-1.1_000378 754252.PFREUD_00360 3.4e-304 1050.4 Propionibacteriales ko:K06148 ko00000,ko02000 3.A.1 Bacteria 2GJ8B@201174,4DNKK@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM14217-p1-1.1_000380 754252.PFREUD_00340 9.9e-230 802.4 Propionibacteriales Bacteria 2GK05@201174,4DNXZ@85009,COG1473@1,COG1473@2 NA|NA|NA S Peptidase dimerisation domain gnl|extdb|FAM14217-p1-1.1_000381 754252.PFREUD_00330 3.3e-250 870.5 Actinobacteria ko:K03761,ko:K03762 ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 Bacteria 2GIYR@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily gnl|extdb|FAM14217-p1-1.1_000382 754252.PFREUD_00320 1.6e-269 934.9 Propionibacteriales Bacteria 2GIXR@201174,4DNF6@85009,COG4585@1,COG4585@2 NA|NA|NA T Putative sensor gnl|extdb|FAM14217-p1-1.1_000384 754252.PFREUD_00300 0.0 1083.6 Actinobacteria ko:K06609 ko00000,ko02000 2.A.1.1.26 Bacteria 2H1X6@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000385 754252.PFREUD_00290 7.1e-230 803.1 Actinobacteria Bacteria 2GK0F@201174,COG0673@1,COG0673@2 NA|NA|NA E oxidoreductase gnl|extdb|FAM14217-p1-1.1_000387 1171373.PACID_09350 2.1e-55 222.6 Actinobacteria ko:K02529,ko:K06145 ko00000,ko03000 Bacteria 2GK1X@201174,COG1609@1,COG1609@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000392 754252.PFREUD_00220 1.6e-83 315.5 Propionibacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GKZP@201174,4DR9G@85009,COG3266@1,COG3266@2 NA|NA|NA S Transmembrane domain of unknown function (DUF3566) gnl|extdb|FAM14217-p1-1.1_000393 754252.PFREUD_00210 2.3e-217 761.1 Bacteria pflA 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 Bacteria COG1180@1,COG1180@2 NA|NA|NA C glycyl-radical enzyme activating activity gnl|extdb|FAM14217-p1-1.1_000394 754252.PFREUD_00200 1.1e-106 392.5 Actinobacteria ko:K06990,ko:K09141 ko00000,ko04812 Bacteria 2ISCW@201174,COG2078@1,COG2078@2 NA|NA|NA S AMMECR1 gnl|extdb|FAM14217-p1-1.1_000395 754252.PFREUD_00190 9.3e-144 516.2 Bacteria ko:K06990 ko00000,ko04812 Bacteria COG1355@1,COG1355@2 NA|NA|NA C regulation of microtubule-based process gnl|extdb|FAM14217-p1-1.1_000397 754252.PFREUD_00170 3.8e-162 577.4 Actinobacteria Bacteria 2CR6U@1,2IRNY@201174,32SNH@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000398 754252.PFREUD_00160 0.0 1788.5 Propionibacteriales gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJ2Q@201174,4DN2Z@85009,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gnl|extdb|FAM14217-p1-1.1_000401 754252.PFREUD_24230 4.9e-259 899.8 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000402 1151119.KB895488_gene1067 1.9e-103 382.5 Micrococcaceae Bacteria 1W8X3@1268,2GMQQ@201174,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase like family 2 gnl|extdb|FAM14217-p1-1.1_000403 1449044.JMLE01000005_gene684 1.9e-74 286.6 Actinobacteria rfbX GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944 ko:K03328,ko:K18799 ko00000,ko01005,ko02000 2.A.66.2,2.A.66.2.1 Bacteria 2IIX6@201174,COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process gnl|extdb|FAM14217-p1-1.1_000404 754252.PFREUD_00540 8e-247 859.4 Propionibacteriales rmlC 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNY8@201174,4DN84@85009,COG1091@1,COG1091@2,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose gnl|extdb|FAM14217-p1-1.1_000405 754252.PFREUD_00550 1.2e-193 682.2 Propionibacteriales rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNDU@201174,4DPM2@85009,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily gnl|extdb|FAM14217-p1-1.1_000406 754252.PFREUD_00560 0.0 1568.1 Bacteria acm2 ko:K02395 ko00000,ko02035 Bacteria COG1705@1,COG1705@2,COG5479@1,COG5479@2 NA|NA|NA M isomerase activity gnl|extdb|FAM14217-p1-1.1_000408 754252.PFREUD_00570 7e-236 822.8 Propionibacteriales glf GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0071554,GO:0071766,GO:0071840,GO:0071944,GO:0097159,GO:1901265,GO:1901363 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 2GK2Z@201174,4DNBC@85009,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase gnl|extdb|FAM14217-p1-1.1_000409 754252.PFREUD_00580 0.0 1153.7 Propionibacteriales glfT GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009273,GO:0009987,GO:0010383,GO:0016020,GO:0016043,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0022607,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0035250,GO:0035496,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046483,GO:0052573,GO:0055086,GO:0070589,GO:0070592,GO:0071554,GO:0071555,GO:0071704,GO:0071766,GO:0071769,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901576,GO:1903509 2.4.1.288 ko:K16650 ko00000,ko01000,ko01003 GT2 iNJ661.Rv3808c Bacteria 2GM9N@201174,4DPRT@85009,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 gnl|extdb|FAM14217-p1-1.1_000410 754252.PFREUD_00590 8.8e-154 549.7 Propionibacteriales rgpC ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GP5K@201174,4DQ8I@85009,COG1682@1,COG1682@2 NA|NA|NA GM ABC-2 type transporter gnl|extdb|FAM14217-p1-1.1_000412 754252.PFREUD_00610 2.6e-255 888.3 Actinobacteria lgtD ko:K16710 ko00000 Bacteria 2IK1R@201174,COG1216@1,COG1216@2,COG2327@1,COG2327@2 NA|NA|NA S Psort location Cytoplasmic, score gnl|extdb|FAM14217-p1-1.1_000413 754252.PFREUD_00620 1.3e-135 489.2 Propionibacteriales 2.4.1.303 ko:K18788 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 2HFAF@201174,4DTEA@85009,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 gnl|extdb|FAM14217-p1-1.1_000414 754252.PFREUD_00630 1.9e-167 595.1 Propionibacteriales TTHA0885 Bacteria 2GMQQ@201174,4DN24@85009,COG1216@1,COG1216@2 NA|NA|NA M overlaps another CDS with the same product name gnl|extdb|FAM14217-p1-1.1_000415 754252.PFREUD_00640 2.6e-65 254.6 Propionibacteriales thiX 1.8.1.8 ko:K02199,ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 2IKMI@201174,4DRPF@85009,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin gnl|extdb|FAM14217-p1-1.1_000416 754252.PFREUD_00650 1.1e-70 272.7 Propionibacteriales Bacteria 2AN8T@1,2I81P@201174,327DN@2,4DWJ2@85009 NA|NA|NA S Domain of unknown function (DUF4395) gnl|extdb|FAM14217-p1-1.1_000417 754252.PFREUD_00670 1.8e-147 528.5 Propionibacteriales 2.3.1.51,6.2.1.3 ko:K00655,ko:K01897 ko00061,ko00071,ko00561,ko00564,ko01100,ko01110,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00561,map00564,map01100,map01110,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086,M00089 R01280,R02241,R09381 RC00004,RC00014,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2IA3W@201174,4DWQN@85009,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases gnl|extdb|FAM14217-p1-1.1_000418 754252.PFREUD_00680 1.2e-149 535.8 Propionibacteriales ko:K07124 ko00000 Bacteria 2GKJE@201174,4DQTE@85009,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM14217-p1-1.1_000419 754252.PFREUD_00690 3e-223 780.8 Propionibacteriales ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1,2.7.2.15 ko:K00925,ko:K19697 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1034,iIT341.HP0903m,iNJ661.Rv0409 Bacteria 2GJAW@201174,4DP4Y@85009,COG0282@1,COG0282@2 NA|NA|NA C Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction gnl|extdb|FAM14217-p1-1.1_000420 754252.PFREUD_00700 3.4e-267 927.2 Propionibacteriales pta GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0006082,GO:0006083,GO:0006950,GO:0008150,GO:0008152,GO:0008959,GO:0009058,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016053,GO:0016407,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0030145,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050182,GO:0050896,GO:0055114,GO:0071704,GO:0072330,GO:1901576 1.1.1.40,2.3.1.19,2.3.1.8,3.6.3.21 ko:K00029,ko:K00625,ko:K00634,ko:K02028,ko:K04020,ko:K13788 ko00430,ko00620,ko00640,ko00650,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00172,M00236,M00357,M00579 R00216,R00230,R00921,R01174 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iAF987.Gmet_1035,iAF987.Gmet_1637,iAF987.Gmet_2098,iE2348C_1286.E2348C_2692,iSB619.SA_RS03155,iYO844.BSU24090 Bacteria 2GJ5U@201174,4DN2E@85009,COG0280@1,COG0280@2 NA|NA|NA C belongs to the CobB CobQ family gnl|extdb|FAM14217-p1-1.1_000423 33876.JNXY01000017_gene7333 1.2e-10 74.3 Micromonosporales ko:K02005,ko:K02022 ko00000 Bacteria 2IFY7@201174,4DBFI@85008,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family gnl|extdb|FAM14217-p1-1.1_000425 471856.Jden_0219 3.2e-20 106.3 Bacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria COG0577@1,COG0577@2 NA|NA|NA V efflux transmembrane transporter activity gnl|extdb|FAM14217-p1-1.1_000426 754252.PFREUD_00710 0.0 2125.5 Actinobacteria helZ Bacteria 2GISC@201174,COG0553@1,COG0553@2 NA|NA|NA L helicase gnl|extdb|FAM14217-p1-1.1_000429 754252.PFREUD_23010 1.7e-148 531.9 Propionibacteriales nfo GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJJQ@201174,4DN5G@85009,COG0648@1,COG0648@2 NA|NA|NA L Xylose isomerase-like TIM barrel gnl|extdb|FAM14217-p1-1.1_000430 754252.PFREUD_23000 0.0 1253.8 Actinobacteria PPA2234 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,COG1022@1,COG1022@2 NA|NA|NA I AMP-dependent synthetase and ligase gnl|extdb|FAM14217-p1-1.1_000431 754252.PFREUD_22990 6.3e-272 943.0 Actinobacteria ko:K06609 ko00000,ko02000 2.A.1.1.26 Bacteria 2GJF6@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000432 754252.PFREUD_22980 4.2e-152 543.9 Propionibacteriales gip 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 2GKPC@201174,4DR0F@85009,COG3622@1,COG3622@2 NA|NA|NA G Xylose isomerase-like TIM barrel gnl|extdb|FAM14217-p1-1.1_000433 754252.PFREUD_22970 6.3e-185 653.3 Actinobacteria ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,COG1609@1,COG1609@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000434 754252.PFREUD_22960 1.2e-103 382.5 Propionibacteriales pncA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 ko:K08281,ko:K12132 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000,ko01001 iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802 Bacteria 2IFQW@201174,4DQD6@85009,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family gnl|extdb|FAM14217-p1-1.1_000435 754252.PFREUD_22950 1e-179 636.0 Propionibacteriales ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJQW@201174,4DQ7J@85009,COG0834@1,COG0834@2 NA|NA|NA ET amino acid gnl|extdb|FAM14217-p1-1.1_000437 754252.PFREUD_22930 3.5e-147 527.7 Propionibacteriales pknD ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJQW@201174,4DQ7J@85009,COG0834@1,COG0834@2 NA|NA|NA ET amino acid gnl|extdb|FAM14217-p1-1.1_000438 754252.PFREUD_22920 1.8e-165 588.6 Propionibacteriales ko:K02029,ko:K10009 ko02010,map02010 M00234,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14 Bacteria 2GJJ9@201174,4DQAE@85009,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000439 754252.PFREUD_22910 2.2e-151 541.6 Propionibacteriales 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2GIZW@201174,4DNUK@85009,COG1126@1,COG1126@2 NA|NA|NA E Polar amino acid transport system gnl|extdb|FAM14217-p1-1.1_000440 754252.PFREUD_22900 4.4e-85 321.2 Propionibacteriales padR ko:K10947 ko00000,ko03000 Bacteria 2IFDN@201174,4DR1C@85009,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family gnl|extdb|FAM14217-p1-1.1_000441 754252.PFREUD_22890 0.0 1426.8 Propionibacteriales nadE GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 2H2H9@201174,4DNXS@85009,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source gnl|extdb|FAM14217-p1-1.1_000442 754252.PFREUD_22880 3.1e-236 823.9 Propionibacteriales malY 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 2GJFQ@201174,4DQQR@85009,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase class I and II gnl|extdb|FAM14217-p1-1.1_000443 754252.PFREUD_22870 1.7e-78 298.5 Actinobacteria lacB GO:0003674,GO:0003824,GO:0004751,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.1.1.222,2.1.1.64,5.3.1.26,5.3.1.6 ko:K00568,ko:K01808,ko:K01819 ko00030,ko00051,ko00052,ko00130,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00052,map00130,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00117,M00165,M00167 R01056,R03240,R04988,R05614,R08769,R08781,R09030 RC00003,RC00376,RC00392,RC00434,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJG@201174,COG0698@1,COG0698@2 NA|NA|NA G Ribose 5-phosphate isomerase gnl|extdb|FAM14217-p1-1.1_000444 754252.PFREUD_22860 3.3e-186 657.5 Actinobacteria pdxA 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 Bacteria 2GRPG@201174,COG1995@1,COG1995@2 NA|NA|NA H Belongs to the PdxA family gnl|extdb|FAM14217-p1-1.1_000445 754252.PFREUD_22850 6e-228 796.6 Propionibacteriales ko:K03299 ko00000,ko02000 2.A.8 Bacteria 2GITQ@201174,4DN1V@85009,COG2610@1,COG2610@2 NA|NA|NA EG GntP family permease gnl|extdb|FAM14217-p1-1.1_000446 754252.PFREUD_22840 3e-178 630.9 Actinobacteria Bacteria 2IB5E@201174,COG1082@1,COG1082@2 NA|NA|NA G isomerase gnl|extdb|FAM14217-p1-1.1_000447 754252.PFREUD_22830 1.3e-229 802.0 Actinobacteria ko:K08194 ko00000,ko02000 2.A.1.14.7 Bacteria 2IE55@201174,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000448 1221522.B723_06785 1.4e-30 139.0 Pseudomonas fluorescens group ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 1MVG0@1224,1RNCH@1236,1YR7K@136843,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase gnl|extdb|FAM14217-p1-1.1_000449 754252.PFREUD_25090 5.1e-256 889.8 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000452 754252.PFREUD_22750 1.5e-98 365.5 Bacteria Bacteria COG1961@1,COG1961@2 NA|NA|NA L recombinase activity gnl|extdb|FAM14217-p1-1.1_000453 754252.PFREUD_22760 5.9e-135 486.9 Actinobacteria Bacteria 2I3Y9@201174,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system gnl|extdb|FAM14217-p1-1.1_000454 754252.PFREUD_22770 1.9e-58 231.5 Bacteria Bacteria 2ES0Y@1,2ZIQJ@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000456 754252.PFREUD_22790 4.2e-80 303.9 Actinobacteria ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2IRG0@201174,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family gnl|extdb|FAM14217-p1-1.1_000457 754252.PFREUD_22800 0.0 1207.6 Propionibacteriales kup ko:K03549 ko00000,ko02000 2.A.72 Bacteria 2GMPQ@201174,4DU3B@85009,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell gnl|extdb|FAM14217-p1-1.1_000458 754252.PFREUD_25090 5.1e-256 889.8 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000459 754252.PFREUD_22700 3.2e-80 304.3 Bacteria Bacteria 2DSUA@1,33HFA@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000460 754252.PFREUD_22690 8.4e-75 286.2 Bacteria Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM14217-p1-1.1_000461 754252.PFREUD_22680 0.0 1498.4 Propionibacteriales glgX 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2GJ00@201174,4DN1Q@85009,COG1523@1,COG1523@2 NA|NA|NA G Carbohydrate-binding module 48 (Isoamylase N-terminal domain) gnl|extdb|FAM14217-p1-1.1_000463 1122998.AUHZ01000028_gene9 1.1e-49 202.2 Actinobacteria Bacteria 2ATJW@1,2IKN0@201174,31J3Z@2 NA|NA|NA S Domain of unknown function (DUF4193) gnl|extdb|FAM14217-p1-1.1_000464 1122998.AUHZ01000028_gene10 1.7e-176 625.2 Actinobacteria ko:K03733 ko00000,ko03036 Bacteria 2IGA2@201174,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family gnl|extdb|FAM14217-p1-1.1_000465 1122998.AUHZ01000028_gene11 5.1e-62 243.4 Propionibacteriales Bacteria 2I9B8@201174,4DTJE@85009,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family gnl|extdb|FAM14217-p1-1.1_000466 754252.PFREUD_22630 2.9e-93 347.8 Actinobacteria Bacteria 2I9B8@201174,COG0582@1,COG0582@2 NA|NA|NA L Integrase gnl|extdb|FAM14217-p1-1.1_000469 754252.PFREUD_22580 4e-23 113.2 Bacteria tnp3521a1 ko:K07483 ko00000 Bacteria COG2963@1,COG2963@2 NA|NA|NA L transposase activity gnl|extdb|FAM14217-p1-1.1_000470 1287475.HMPREF1650_06440 2.8e-40 171.0 Corynebacteriaceae ko:K07483 ko00000 Bacteria 22N9U@1653,2IQ8F@201174,COG2963@1,COG2963@2 NA|NA|NA L transposase gnl|extdb|FAM14217-p1-1.1_000471 1122998.AUHZ01000028_gene15 9.5e-222 775.8 Propionibacteriales insI1 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 ko:K07482 ko00000 Bacteria 2GMZX@201174,4DQAY@85009,COG2826@1,COG2826@2 NA|NA|NA L Integrase, catalytic region gnl|extdb|FAM14217-p1-1.1_000472 1089455.MOPEL_017_00040 2.9e-64 251.5 Dermatophilaceae Bacteria 2CAW2@1,2IB15@201174,32RS7@2,4F7YK@85018 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000474 754252.PFREUD_25090 5.1e-256 889.8 Actinobacteria Bacteria 2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000475 754252.PFREUD_22510 1.3e-101 375.6 Propionibacteriales ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 2HZHU@201174,4DSUW@85009,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase gnl|extdb|FAM14217-p1-1.1_000477 1122138.AQUZ01000008_gene3765 4.3e-194 684.1 Propionibacteriales Bacteria 2GJK7@201174,4DTG9@85009,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000480 754252.PFREUD_22480 3.6e-126 457.6 Propionibacteriales Bacteria 2IKBV@201174,4DVIQ@85009,COG1802@1,COG1802@2 NA|NA|NA K FCD gnl|extdb|FAM14217-p1-1.1_000481 754252.PFREUD_22470 0.0 1089.7 Propionibacteriales dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0030246,GO:0042221,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 2.7.1.121,2.7.1.209,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K20901 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059,R11460 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJV9@201174,4DN06@85009,COG2376@1,COG2376@2 NA|NA|NA G Dihydroxyacetone kinase gnl|extdb|FAM14217-p1-1.1_000482 754252.PFREUD_22460 7e-141 506.5 Propionibacteriales tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009758,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016854,GO:0016857,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.1.3.39,5.3.1.1,5.3.1.33 ko:K00927,ko:K01803,ko:K20905,ko:K21910 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXZ@201174,4DP7B@85009,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) gnl|extdb|FAM14217-p1-1.1_000483 754252.PFREUD_22450 1.4e-145 522.3 Propionibacteriales Bacteria 2IBBZ@201174,4DQU0@85009,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain gnl|extdb|FAM14217-p1-1.1_000484 754252.PFREUD_22440 1.2e-120 439.1 Propionibacteriales Bacteria 2GKK7@201174,4DRYB@85009,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM14217-p1-1.1_000485 754252.PFREUD_22430 3.5e-85 320.9 Actinobacteria rpiB GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIDQ@201174,COG0698@1,COG0698@2 NA|NA|NA G Ribose 5-phosphate isomerase gnl|extdb|FAM14217-p1-1.1_000487 754252.PFREUD_22410 1.2e-168 599.0 Propionibacteriales araL 3.1.3.41 ko:K01101,ko:K02101,ko:K02566 ko00627,ko01120,map00627,map01120 R03024 RC00151 ko00000,ko00001,ko01000 Bacteria 2IBHB@201174,4DQQ5@85009,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase gnl|extdb|FAM14217-p1-1.1_000488 754252.PFREUD_22400 0.0 1082.4 Propionibacteriales Bacteria 2I41D@201174,4DQK0@85009,COG1069@1,COG1069@2 NA|NA|NA G FGGY family of carbohydrate kinases, N-terminal domain gnl|extdb|FAM14217-p1-1.1_000489 754252.PFREUD_22380 2.7e-268 930.6 Propionibacteriales egsA 1.1.1.261 ko:K00096 ko00564,map00564 R05679,R05680 RC00029 ko00000,ko00001,ko01000 Bacteria 2GKWA@201174,4DQ5E@85009,COG0371@1,COG0371@2 NA|NA|NA C Iron-containing alcohol dehydrogenase gnl|extdb|FAM14217-p1-1.1_000490 754252.PFREUD_22370 8.5e-299 1032.3 Propionibacteriales araB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008741,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046373,GO:0046835,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 iBWG_1329.BWG_0059,iECH74115_1262.ECH74115_0068,iECSP_1301.ECSP_0067,iECs_1301.ECs0067,iG2583_1286.G2583_0066,iPC815.YPO2254,iZ_1308.Z0072 Bacteria 2H531@201174,4DP9J@85009,COG1069@1,COG1069@2 NA|NA|NA G FGGY family of carbohydrate kinases, C-terminal domain gnl|extdb|FAM14217-p1-1.1_000491 754252.PFREUD_22360 0.0 1383.2 Propionibacteriales tkt GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ1K@201174,4DN1Y@85009,COG0021@1,COG0021@2 NA|NA|NA G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate gnl|extdb|FAM14217-p1-1.1_000493 754252.PFREUD_22340 0.0 1522.7 Propionibacteriales uvrA2 Bacteria 2GJUV@201174,4DTER@85009,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter gnl|extdb|FAM14217-p1-1.1_000494 754252.PFREUD_22330 1.9e-169 601.7 Actinobacteria yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.2.1.9,5.1.3.15 ko:K01687,ko:K01792 ko00010,ko00290,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00010,map00290,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R01209,R02739,R04441,R05070 RC00468,RC00563,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIUH@201174,COG0676@1,COG0676@2 NA|NA|NA G Belongs to the glucose-6-phosphate 1-epimerase family gnl|extdb|FAM14217-p1-1.1_000495 754252.PFREUD_22320 2e-152 545.0 Actinobacteria ko:K17882 ko00000,ko01000,ko01504 Bacteria 2I71C@201174,COG1708@1,COG1708@2 NA|NA|NA L Domain of unknown function (DUF4111) gnl|extdb|FAM14217-p1-1.1_000498 754252.PFREUD_22290 6.1e-235 819.7 Propionibacteriales 2.4.1.250 ko:K15521 ko00000,ko01000 Bacteria 2GJ57@201174,4DN29@85009,COG0438@1,COG0438@2 NA|NA|NA M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway gnl|extdb|FAM14217-p1-1.1_000499 754252.PFREUD_22280 5.1e-153 547.0 Actinobacteria 3.5.1.103 ko:K15525 ko00000,ko01000 Bacteria 2GKUM@201174,COG2120@1,COG2120@2 NA|NA|NA S Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway gnl|extdb|FAM14217-p1-1.1_000500 754252.PFREUD_22270 1e-97 362.8 Propionibacteriales Bacteria 2H3AT@201174,4DS50@85009,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) gnl|extdb|FAM14217-p1-1.1_000501 754252.PFREUD_22260 5.6e-183 646.7 Propionibacteriales prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKR2@201174,4DQ3C@85009,COG0462@1,COG0462@2 NA|NA|NA EF Phosphoribosyl synthetase-associated domain gnl|extdb|FAM14217-p1-1.1_000502 754252.PFREUD_22250 1.6e-128 465.3 Actinobacteria guaA_1 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GNA6@201174,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase gnl|extdb|FAM14217-p1-1.1_000503 754252.PFREUD_22240 1.6e-203 715.3 Actinobacteria yceJ Bacteria 2IAX5@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000504 754252.PFREUD_22230 2e-55 221.5 Propionibacteriales Bacteria 2IIEZ@201174,4DRBZ@85009,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000506 754252.PFREUD_22210 3.8e-87 327.4 Bacteria ko:K03830 ko00000,ko01000 Bacteria COG1246@1,COG1246@2 NA|NA|NA E Belongs to the acetyltransferase family. ArgA subfamily gnl|extdb|FAM14217-p1-1.1_000507 754252.PFREUD_22200 2.2e-57 228.0 Actinobacteria cmtR GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K21885 ko00000,ko03000 Bacteria 2IMDE@201174,COG0640@1,COG0640@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000508 754252.PFREUD_22190 0.0 1179.9 Propionibacteriales ko:K12954 ko00000,ko01000 3.A.3 Bacteria 2GIRF@201174,4DPEN@85009,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase gnl|extdb|FAM14217-p1-1.1_000513 754252.PFREUD_22140 4.8e-108 397.1 Bacteria Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000514 754252.PFREUD_22130 2.4e-119 434.9 Actinobacteria Bacteria 2GMI4@201174,COG2860@1,COG2860@2 NA|NA|NA S membrane gnl|extdb|FAM14217-p1-1.1_000515 754252.PFREUD_22120 2.8e-85 321.2 Propionibacteriales Bacteria 2IR93@201174,4DW2A@85009,COG1261@1,COG1261@2 NA|NA|NA NO SAF domain gnl|extdb|FAM14217-p1-1.1_000516 754252.PFREUD_22110 1.5e-186 658.7 Propionibacteriales ko:K03496 ko00000,ko03036,ko04812 Bacteria 2I57A@201174,4DS3J@85009,COG1192@1,COG1192@2 NA|NA|NA D Involved in chromosome partitioning gnl|extdb|FAM14217-p1-1.1_000522 1479623.JHEL01000015_gene743 1.1e-70 273.9 Microbacteriaceae Bacteria 2EZFS@1,2IJ1W@201174,33SKZ@2,4FPSP@85023 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000523 1415166.NONO_c20930 6.2e-135 488.0 Actinobacteria Bacteria 2I9ST@201174,COG0846@1,COG0846@2 NA|NA|NA K SIR2-like domain gnl|extdb|FAM14217-p1-1.1_000524 1385519.N801_18140 1.9e-10 72.0 Actinobacteria Bacteria 2EEQX@1,2IFKH@201174,338IM@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000525 1122933.JNIY01000003_gene3 3.9e-20 104.0 Actinobacteria Bacteria 2ANP7@1,2ISEA@201174,31DNP@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000528 1122998.AUHZ01000005_gene953 1.2e-274 951.8 Propionibacteriales Bacteria 2DBQ2@1,2IF6C@201174,2ZABR@2,4DVGF@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000529 710111.FraQA3DRAFT_1231 5.8e-37 160.6 Actinobacteria Bacteria 2B7WM@1,2H50U@201174,3213J@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000530 525268.HMPREF0308_0409 1.8e-62 247.3 Corynebacteriaceae Bacteria 22QE9@1653,2EA2P@1,2IR5I@201174,3347U@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000531 1122998.AUHZ01000005_gene954 0.0 1613.2 Actinobacteria 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 2I9VK@201174,COG1061@1,COG1061@2 NA|NA|NA KL Type III restriction enzyme res subunit gnl|extdb|FAM14217-p1-1.1_000532 1238186.AOCN01000012_gene1242 2e-262 911.8 Microbacteriaceae 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 2IP0P@201174,4FS5S@85023,COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family gnl|extdb|FAM14217-p1-1.1_000538 1122998.AUHZ01000005_gene961 3.4e-178 630.9 Actinobacteria Bacteria 2GV6D@201174,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family gnl|extdb|FAM14217-p1-1.1_000539 1122998.AUHZ01000005_gene962 0.0 1250.7 Actinobacteria Bacteria 2EKY7@1,2IBEG@201174,33EMR@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000541 754252.PFREUD_22090 1.2e-152 545.8 Propionibacteriales Bacteria 2GN6E@201174,4DQV5@85009,COG4965@1,COG4965@2 NA|NA|NA U Type II secretion system (T2SS), protein F gnl|extdb|FAM14217-p1-1.1_000542 754252.PFREUD_22080 5.2e-159 567.0 Actinobacteria ko:K12511 ko00000,ko02044 Bacteria 2HZTC@201174,COG2064@1,COG2064@2 NA|NA|NA NU type II secretion system protein gnl|extdb|FAM14217-p1-1.1_000544 1035308.AQYY01000002_gene277 3.7e-07 61.2 Bacteria Bacteria 2EMTJ@1,33FFX@2 NA|NA|NA S TadE-like protein gnl|extdb|FAM14217-p1-1.1_000545 1122994.AUFR01000011_gene2038 1.5e-25 122.5 Bacteria Bacteria COG4961@1,COG4961@2 NA|NA|NA U PFAM TadE family protein gnl|extdb|FAM14217-p1-1.1_000546 754252.PFREUD_22040 0.0 1879.4 Actinobacteria ygaU GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 ko:K21687 ko00000 GH23 Bacteria 2GWK7@201174,COG1652@1,COG1652@2 NA|NA|NA NU LysM domain gnl|extdb|FAM14217-p1-1.1_000547 754252.PFREUD_22030 1.7e-97 362.1 Propionibacteriales yhgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 2GMCM@201174,4DQEH@85009,COG2095@1,COG2095@2 NA|NA|NA U MarC family integral membrane protein gnl|extdb|FAM14217-p1-1.1_000548 754252.PFREUD_22020 2.1e-241 841.3 Propionibacteriales 2.7.4.9 ko:K00943,ko:K08217 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 br01600,ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 Bacteria 2GK5A@201174,4DQ23@85009,COG2270@1,COG2270@2 NA|NA|NA S Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000549 754252.PFREUD_21990 1.8e-165 588.6 Bacteria Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation gnl|extdb|FAM14217-p1-1.1_000550 754252.PFREUD_21980 2.4e-116 424.9 Propionibacteriales Bacteria 2GJ46@201174,4DPI9@85009,COG2197@1,COG2197@2 NA|NA|NA T Two component transcriptional regulator, LuxR family gnl|extdb|FAM14217-p1-1.1_000551 754252.PFREUD_21970 2.2e-241 841.3 Propionibacteriales Bacteria 2GJEG@201174,4DN2N@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM14217-p1-1.1_000552 754252.PFREUD_21960 0.0 1135.9 Bacteria Bacteria 2CC7E@1,2Z7WG@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000553 754252.PFREUD_21930 3e-276 957.2 Actinobacteria ko:K09684 ko00000,ko03000 Bacteria 2GNDH@201174,COG2508@1,COG2508@2 NA|NA|NA QT Regulator of polyketide synthase expression gnl|extdb|FAM14217-p1-1.1_000556 754252.PFREUD_21900 1.3e-198 698.7 Propionibacteriales 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GISW@201174,4DPID@85009,COG1063@1,COG1063@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM14217-p1-1.1_000557 1122138.AQUZ01000008_gene3765 4.1e-213 747.3 Propionibacteriales Bacteria 2GJK7@201174,4DTG9@85009,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000558 754252.PFREUD_21890 4.3e-107 394.0 Propionibacteriales yecS ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2ISHP@201174,4DV4K@85009,COG0765@1,COG0765@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000559 754252.PFREUD_21880 6.2e-101 373.6 Actinobacteria hisM ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GM0I@201174,COG0765@1,COG0765@2 NA|NA|NA E amino acid ABC transporter gnl|extdb|FAM14217-p1-1.1_000560 754252.PFREUD_21870 3.5e-126 458.0 Actinobacteria ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2IPCR@201174,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins gnl|extdb|FAM14217-p1-1.1_000561 754252.PFREUD_21860 3.5e-146 524.2 Propionibacteriales 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2GIZW@201174,4DP52@85009,COG1126@1,COG1126@2 NA|NA|NA E amino acid ABC transporter, ATP-binding protein gnl|extdb|FAM14217-p1-1.1_000562 754252.PFREUD_21850 9.2e-65 252.7 Bacteria Bacteria COG0251@1,COG0251@2 NA|NA|NA J oxidation-reduction process gnl|extdb|FAM14217-p1-1.1_000563 754252.PFREUD_21840 2.5e-236 824.3 Propionibacteriales dadA 1.4.5.1 ko:K00285 ko00360,map00360 R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 Bacteria 2GMR7@201174,4DPH7@85009,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase gnl|extdb|FAM14217-p1-1.1_000564 754252.PFREUD_21830 7.2e-149 533.1 Actinobacteria 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 iHN637.CLJU_RS14520 Bacteria 2ICDA@201174,COG1794@1,COG1794@2 NA|NA|NA M racemase activity, acting on amino acids and derivatives gnl|extdb|FAM14217-p1-1.1_000565 754252.PFREUD_21820 2.4e-80 304.7 Actinobacteria hit ko:K02503 ko00000,ko04147 Bacteria 2IKWU@201174,COG0537@1,COG0537@2 NA|NA|NA FG Histidine triad (Hit) protein gnl|extdb|FAM14217-p1-1.1_000566 754252.PFREUD_21810 8.5e-102 376.3 Propionibacteriales moaB Bacteria 2II28@201174,4DQU7@85009,COG0521@1,COG0521@2 NA|NA|NA H Probable molybdopterin binding domain gnl|extdb|FAM14217-p1-1.1_000567 754252.PFREUD_21800 9e-91 339.7 Propionibacteriales moaC 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 2IHR6@201174,4DQPG@85009,COG0315@1,COG0315@2 NA|NA|NA H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) gnl|extdb|FAM14217-p1-1.1_000569 754252.PFREUD_21770 5.1e-159 567.0 Propionibacteriales moeZ 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 R07459,R07461 RC00043 ko00000,ko00001,ko01000 Bacteria 2GJB6@201174,4DNCG@85009,COG0476@1,COG0476@2 NA|NA|NA H ThiF family gnl|extdb|FAM14217-p1-1.1_000570 754252.PFREUD_21760 1.7e-72 278.5 Propionibacteriales moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.80,2.8.1.11,2.8.1.12 ko:K03635,ko:K21147 ko00790,ko01100,ko04122,map00790,map01100,map04122 R07459,R07461,R09395 RC00043,RC02507 ko00000,ko00001,ko01000 Bacteria 2IQ9F@201174,4DR9R@85009,COG0314@1,COG0314@2 NA|NA|NA H MoaE protein gnl|extdb|FAM14217-p1-1.1_000572 649743.HMPREF0972_01555 7e-98 363.6 Actinobacteria narI GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 ko:K00370,ko:K00374,ko:K02575 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00615,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.8,5.A.3.1 iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897 Bacteria 2GJVI@201174,4D3AB@85005,COG2181@1,COG2181@2 NA|NA|NA C Respiratory nitrate reductase, gamma subunit gnl|extdb|FAM14217-p1-1.1_000573 754252.PFREUD_21730 3.2e-120 438.0 Propionibacteriales narJ GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 ko:K00373,ko:K17052 ko02020,map02020 ko00000,ko00001,ko02000 5.A.3.8 iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,iYO844.BSU37260,ic_1306.c1687 Bacteria 2IAQV@201174,4DRDB@85009,COG2180@1,COG2180@2 NA|NA|NA C Nitrate reductase delta subunit gnl|extdb|FAM14217-p1-1.1_000574 1203556.HMPREF1478_00889 1.3e-255 888.6 Actinobacteria narH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189 Bacteria 2GJ8P@201174,4D4CE@85005,COG1140@1,COG1140@2 NA|NA|NA C Nitrate reductase beta subunit gnl|extdb|FAM14217-p1-1.1_000575 1227261.HMPREF0043_01372 0.0 2084.7 Actinobacteria narG 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 Bacteria 2GKZU@201174,4D4NX@85005,COG5013@1,COG5013@2 NA|NA|NA C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family gnl|extdb|FAM14217-p1-1.1_000577 1122994.AUFR01000011_gene1979 3.9e-88 332.0 Propionibacteriales moaA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 ko:K03639,ko:K20967 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394,R11372 RC03420,RC03425 ko00000,ko00001,ko01000 Bacteria 2GN0V@201174,4DP3D@85009,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate gnl|extdb|FAM14217-p1-1.1_000578 1122994.AUFR01000011_gene1978 8.7e-52 210.3 Bacteria mobA 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 R11581 ko00000,ko00001,ko01000 Bacteria COG0746@1,COG0746@2 NA|NA|NA H molybdenum cofactor guanylyltransferase activity gnl|extdb|FAM14217-p1-1.1_000579 1120942.AUBM01000003_gene804 8.8e-47 193.4 Actinobacteria mog GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.75,2.8.1.12,4.99.1.12 ko:K03635,ko:K03831,ko:K09121 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395,R09726 RC00002,RC02507 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1969,iECABU_c1320.ECABU_c00100,iECED1_1282.ECED1_0009,iECNA114_1301.ECNA114_4653,iECP_1309.ECP_0010,iECS88_1305.ECS88_0010,iECSF_1327.ECSF_0009,iECUMN_1333.ECUMN_0010,iEcSMS35_1347.EcSMS35_0008,iLF82_1304.LF82_1379,iNRG857_1313.NRG857_00050,iUMN146_1321.UM146_22820 Bacteria 2H57U@201174,4D434@85005,COG0521@1,COG0521@2 NA|NA|NA H Molybdopterin binding domain protein gnl|extdb|FAM14217-p1-1.1_000580 1171373.PACID_02570 4.9e-73 281.2 Propionibacteriales modA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 ko:K02020 ko02010,map02010 M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.8 Bacteria 2GMPF@201174,4DQXM@85009,COG0725@1,COG0725@2 NA|NA|NA P Bacterial extracellular solute-binding protein gnl|extdb|FAM14217-p1-1.1_000582 754252.PFREUD_21700 0.0 2924.4 Propionibacteriales hgdC Bacteria 2I1VH@201174,4DVSF@85009,COG1924@1,COG1924@2,COG3580@1,COG3580@2,COG3581@1,COG3581@2 NA|NA|NA I CoA enzyme activase uncharacterised domain (DUF2229) gnl|extdb|FAM14217-p1-1.1_000583 754252.PFREUD_21690 9.2e-284 982.2 Propionibacteriales 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2IJ@201174,4DN9N@85009,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate gnl|extdb|FAM14217-p1-1.1_000584 754252.PFREUD_21680 3.2e-128 464.5 Propionibacteriales Bacteria 2GIZ3@201174,4DPSU@85009,COG1814@1,COG1814@2 NA|NA|NA S VIT family gnl|extdb|FAM14217-p1-1.1_000585 754252.PFREUD_21670 3.1e-132 477.6 Bacteria Bacteria COG2227@1,COG2227@2 NA|NA|NA H 3-demethylubiquinone-9 3-O-methyltransferase activity gnl|extdb|FAM14217-p1-1.1_000586 754252.PFREUD_21660 6.6e-84 316.6 Actinobacteria lacB GO:0003674,GO:0003824,GO:0004751,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.1.1.222,2.1.1.64,5.3.1.26,5.3.1.6 ko:K00568,ko:K01808,ko:K01819 ko00030,ko00051,ko00052,ko00130,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00052,map00130,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00117,M00165,M00167 R01056,R03240,R04988,R05614,R08769,R08781,R09030 RC00003,RC00376,RC00392,RC00434,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJG@201174,COG0698@1,COG0698@2 NA|NA|NA G Ribose 5-phosphate isomerase gnl|extdb|FAM14217-p1-1.1_000587 754252.PFREUD_21650 5.6e-250 869.8 Propionibacteriales cysN 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDX@201174,4DPIP@85009,COG2895@1,COG2895@2 NA|NA|NA P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily gnl|extdb|FAM14217-p1-1.1_000589 754252.PFREUD_21630 1.4e-141 508.8 Propionibacteriales cysH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2392 Bacteria 2GJ3Z@201174,4DPGD@85009,COG0175@1,COG0175@2 NA|NA|NA EH Belongs to the PAPS reductase family. CysH subfamily gnl|extdb|FAM14217-p1-1.1_000591 754252.PFREUD_21610 4.3e-187 660.6 Propionibacteriales subI GO:0005575,GO:0005623,GO:0042597,GO:0044464 ko:K02048 ko00920,ko02010,map00920,map02010 M00185 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 iJN678.sbpA Bacteria 2GJIK@201174,4DNI4@85009,COG1613@1,COG1613@2 NA|NA|NA P Bacterial extracellular solute-binding protein gnl|extdb|FAM14217-p1-1.1_000592 754252.PFREUD_21600 1.9e-168 598.6 Propionibacteriales cysT GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348 ko:K02018,ko:K02046 ko00920,ko02010,map00920,map02010 M00185,M00189 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3,3.A.1.8 iAPECO1_1312.APECO1_4122,iE2348C_1286.E2348C_2609,iECNA114_1301.ECNA114_2500,iECOK1_1307.ECOK1_2740,iECP_1309.ECP_2447,iECS88_1305.ECS88_2613,iECSF_1327.ECSF_2287,iJN746.PP_5170,iLF82_1304.LF82_0425,iNRG857_1313.NRG857_12150,iSDY_1059.SDY_2620,iUMN146_1321.UM146_04505,iUTI89_1310.UTI89_C2757,iYL1228.KPN_02772 Bacteria 2GP6P@201174,4DNC9@85009,COG0555@1,COG0555@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000594 754252.PFREUD_21580 3.5e-191 674.1 Propionibacteriales cysA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358 3.6.3.25,3.6.3.29 ko:K02017,ko:K02045,ko:K10112,ko:K16787 ko00920,ko02010,map00920,map02010 M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00582,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.1,3.A.1.6.3,3.A.1.8 iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511 Bacteria 2I3KJ@201174,4DNAR@85009,COG1118@1,COG1118@2 NA|NA|NA P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system gnl|extdb|FAM14217-p1-1.1_000595 1064537.AGSO01000018_gene1046 3.9e-126 458.0 Actinobacteria czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 2GMRZ@201174,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter gnl|extdb|FAM14217-p1-1.1_000596 714083.JH370377_gene558 2e-33 148.7 Microbacteriaceae ko:K03892 ko00000,ko03000 Bacteria 2IKUI@201174,4FT7T@85023,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor gnl|extdb|FAM14217-p1-1.1_000597 754252.PFREUD_21570 6.2e-114 417.2 Propionibacteriales drrB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I5GM@201174,4DPYQ@85009,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein gnl|extdb|FAM14217-p1-1.1_000598 754252.PFREUD_21560 1.9e-179 635.2 Propionibacteriales drrA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,4DNPQ@85009,COG1131@1,COG1131@2 NA|NA|NA V daunorubicin resistance ABC transporter gnl|extdb|FAM14217-p1-1.1_000599 754252.PFREUD_21550 2.6e-94 351.3 Bacteria effR Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM14217-p1-1.1_000600 754252.PFREUD_21540 6.8e-231 806.6 Propionibacteriales pntA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 iEcE24377_1341.EcE24377A_1810 Bacteria 2I2FZ@201174,4DNG1@85009,COG3288@1,COG3288@2 NA|NA|NA C NAD(P) transhydrogenase, alpha subunit gnl|extdb|FAM14217-p1-1.1_000601 754252.PFREUD_21530 2.8e-260 904.0 Actinobacteria pntB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 iSBO_1134.SBO_1534,iYL1228.KPN_01527 Bacteria 2GNKB@201174,COG1282@1,COG1282@2 NA|NA|NA C the transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane gnl|extdb|FAM14217-p1-1.1_000602 1032480.MLP_46690 9.2e-25 119.8 Propionibacteriales Bacteria 2ICBY@201174,4DR6P@85009,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score gnl|extdb|FAM14217-p1-1.1_000604 754252.PFREUD_21500 0.0 1317.0 Actinobacteria malQ 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 ko:K00700,ko:K00705,ko:K02438,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R02110,R02111,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13,GH77 iJN678.malQ Bacteria 2GM5Z@201174,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase gnl|extdb|FAM14217-p1-1.1_000605 754252.PFREUD_21490 6.6e-76 290.0 Bacteria lacF 2.7.1.196,2.7.1.205,2.7.1.207 ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 Bacteria COG1447@1,COG1447@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system gnl|extdb|FAM14217-p1-1.1_000607 754252.PFREUD_21470 1.1e-223 782.3 Propionibacteriales ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iLJ478.TM1828,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 Bacteria 2GKAX@201174,4DNKD@85009,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate gnl|extdb|FAM14217-p1-1.1_000608 754252.PFREUD_21460 3.4e-115 421.0 Propionibacteriales ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950 Bacteria 2GKC5@201174,4DQ6E@85009,COG0307@1,COG0307@2 NA|NA|NA H riboflavin synthase, alpha gnl|extdb|FAM14217-p1-1.1_000609 754252.PFREUD_21450 2.1e-250 871.3 Propionibacteriales ribA 3.5.4.25,4.1.99.12 ko:K01497,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWJ@201174,4DNA4@85009,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate gnl|extdb|FAM14217-p1-1.1_000610 754252.PFREUD_21440 4.1e-67 260.8 Propionibacteriales ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 Bacteria 2II1Z@201174,4DQTS@85009,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin gnl|extdb|FAM14217-p1-1.1_000612 754252.PFREUD_21420 1.5e-171 609.0 Actinobacteria terZ ko:K05791,ko:K05795 ko00000 Bacteria 2IE9A@201174,COG2310@1,COG2310@2 NA|NA|NA T stress, protein gnl|extdb|FAM14217-p1-1.1_000613 754252.PFREUD_21410 3.3e-123 447.6 Bacteria Bacteria 2CM2Y@1,32S6V@2 NA|NA|NA S Domain of unknown function (DUF3841) gnl|extdb|FAM14217-p1-1.1_000614 754252.PFREUD_21400 0.0 1685.2 Propionibacteriales 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 2I8IG@201174,4DSXW@85009,COG1061@1,COG1061@2 NA|NA|NA KL Type III restriction enzyme, res subunit gnl|extdb|FAM14217-p1-1.1_000615 754252.PFREUD_21390 0.0 1360.1 Propionibacteriales modA 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 2I8FH@201174,4DTYW@85009,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase gnl|extdb|FAM14217-p1-1.1_000617 754252.PFREUD_21360 3.2e-123 447.6 Bacteria Bacteria 2CM2Y@1,32S6V@2 NA|NA|NA S Domain of unknown function (DUF3841) gnl|extdb|FAM14217-p1-1.1_000618 1120797.KB908256_gene2150 3.9e-195 688.0 Mycobacteriaceae opuAB ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 238I1@1762,2GNF7@201174,COG4986@1,COG4986@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000619 1121933.AUHH01000001_gene2079 1.1e-149 536.6 Propionibacteriales abcT3 ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2GN33@201174,4DQMY@85009,COG1116@1,COG1116@2,COG4754@1,COG4754@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_000620 710685.MycrhN_2941 6.1e-257 892.9 Mycobacteriaceae Bacteria 237B6@1762,2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L transposase gnl|extdb|FAM14217-p1-1.1_000624 1449346.JQMO01000003_gene5856 1.9e-13 84.3 Kitasatospora ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2I2Y2@201174,2M2I4@2063,COG3845@1,COG3845@2 NA|NA|NA S AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM14217-p1-1.1_000625 1123065.ATWL01000016_gene1992 7.1e-16 91.7 Actinobacteria ko:K16784,ko:K16785,ko:K16786,ko:K16787,ko:K16927 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GMK1@201174,COG1122@1,COG1122@2 NA|NA|NA P ECF transporter, substrate-specific component gnl|extdb|FAM14217-p1-1.1_000627 2045.KR76_21335 1.7e-52 213.4 Propionibacteriales Bacteria 2GKSJ@201174,4DPXW@85009,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 gnl|extdb|FAM14217-p1-1.1_000628 1122238.AULR01000005_gene2151 7.6e-08 64.3 Microbacteriaceae Bacteria 2ENGC@1,2GXSS@201174,33G3V@2,4FQM6@85023 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000629 765123.HMPREF9621_02073 2.8e-60 239.2 Propionibacteriales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2I9VM@201174,4DRCM@85009,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor type A domain gnl|extdb|FAM14217-p1-1.1_000630 754252.PFREUD_20980 1e-91 343.6 Actinobacteria ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2GJMP@201174,COG2304@1,COG2304@2 NA|NA|NA S von willebrand factor type a gnl|extdb|FAM14217-p1-1.1_000631 1122997.AUDD01000034_gene1939 9.8e-14 84.3 Propionibacteriales Bacteria 2DTHT@1,2I02E@201174,33KE8@2,4DV28@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000632 765123.HMPREF9621_01855 8.3e-26 124.4 Actinobacteria Bacteria 2DDTP@1,2I77I@201174,2ZJ7W@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000634 754252.PFREUD_20940 1.1e-124 452.6 Propionibacteriales mntR ko:K03709 ko00000,ko03000 Bacteria 2GK7P@201174,4DVDS@85009,COG1321@1,COG1321@2 NA|NA|NA K FeoA gnl|extdb|FAM14217-p1-1.1_000635 754252.PFREUD_20930 0.0 1170.2 Actinobacteria Bacteria 2IG31@201174,COG5184@1,COG5184@2 NA|NA|NA DZ PFAM regulator of chromosome condensation, RCC1 gnl|extdb|FAM14217-p1-1.1_000637 754252.PFREUD_20910 0.0 1081.2 Propionibacteriales ko:K03307 ko00000 2.A.21 Bacteria 2GKPW@201174,4DNA9@85009,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family gnl|extdb|FAM14217-p1-1.1_000638 754252.PFREUD_20900 0.0 1234.2 Propionibacteriales thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 iYO844.BSU08790 Bacteria 2GJ3Y@201174,4DN8A@85009,COG0422@1,COG0422@2 NA|NA|NA H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction gnl|extdb|FAM14217-p1-1.1_000639 754252.PFREUD_20890 4.2e-228 797.0 Propionibacteriales Bacteria 2GK0T@201174,4DVC5@85009,COG3214@1,COG3214@2 NA|NA|NA S Winged helix DNA-binding domain gnl|extdb|FAM14217-p1-1.1_000640 754252.PFREUD_20880 2.6e-55 221.1 Actinobacteria Bacteria 2EP9H@1,2HBUH@201174,33GW8@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000643 754252.PFREUD_20850 7.1e-147 526.6 Propionibacteriales Bacteria 2GK7A@201174,4DP7U@85009,COG0500@1,COG2226@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family gnl|extdb|FAM14217-p1-1.1_000644 754252.PFREUD_20840 1.7e-212 745.0 Propionibacteriales namA 1.6.99.1 ko:K00354 R00282 RC00001 ko00000,ko01000 Bacteria 2GK8E@201174,4DP05@85009,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family gnl|extdb|FAM14217-p1-1.1_000645 754252.PFREUD_20830 1.7e-252 878.2 Propionibacteriales lmrB ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 2GIZX@201174,4DNV0@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000646 754252.PFREUD_20820 4.2e-92 344.0 Actinobacteria Bacteria 2GQS5@201174,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain gnl|extdb|FAM14217-p1-1.1_000647 754252.PFREUD_20810 8.7e-251 872.5 Propionibacteriales dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 2GKXQ@201174,4DN0Y@85009,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication gnl|extdb|FAM14217-p1-1.1_000649 754252.PFREUD_20790 9.7e-32 142.1 Propionibacteriales Bacteria 2GQK5@201174,4DSND@85009,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain gnl|extdb|FAM14217-p1-1.1_000650 754252.PFREUD_20780 0.0 1488.4 Propionibacteriales 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2GIRF@201174,4DN8M@85009,COG2217@1,COG2217@2 NA|NA|NA P Heavy-metal-associated domain gnl|extdb|FAM14217-p1-1.1_000653 754252.PFREUD_20750 3.4e-77 294.3 Propionibacteriales Bacteria 2DPPE@1,2IN30@201174,332VJ@2,4DSE1@85009 NA|NA|NA S Putative Actinobacterial Holin-X, holin superfamily III gnl|extdb|FAM14217-p1-1.1_000654 754252.PFREUD_20740 5.1e-226 790.0 Propionibacteriales nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 2GKIK@201174,4DNGP@85009,COG3004@1,COG3004@2 NA|NA|NA P ) H( ) antiporter that extrudes sodium in exchange for external protons gnl|extdb|FAM14217-p1-1.1_000655 754252.PFREUD_20730 1.3e-142 512.3 Propionibacteriales Bacteria 2HWAV@201174,4DQJ7@85009,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain gnl|extdb|FAM14217-p1-1.1_000656 754252.PFREUD_20720 1.7e-190 671.8 Propionibacteriales Bacteria 2I56Y@201174,4DWGF@85009,COG2894@1,COG2894@2 NA|NA|NA D cell division gnl|extdb|FAM14217-p1-1.1_000657 754252.PFREUD_20710 6.6e-215 753.1 Propionibacteriales cpaF ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GKKJ@201174,4DN5K@85009,COG4962@1,COG4962@2 NA|NA|NA U Type II/IV secretion system protein gnl|extdb|FAM14217-p1-1.1_000658 754252.PFREUD_20700 2.8e-140 504.6 Bacteria ko:K12510 ko00000,ko02044 Bacteria COG4965@1,COG4965@2 NA|NA|NA U Type ii secretion system gnl|extdb|FAM14217-p1-1.1_000659 754252.PFREUD_20690 2.5e-127 461.5 Bacteria gspF ko:K12510,ko:K12511 ko00000,ko02044 Bacteria COG2064@1,COG2064@2 NA|NA|NA NU Type II secretion system (T2SS), protein F gnl|extdb|FAM14217-p1-1.1_000660 754252.PFREUD_20680 2.1e-26 125.9 Bacteria yisX Bacteria COG1357@1,COG1357@2 NA|NA|NA S protein homooligomerization gnl|extdb|FAM14217-p1-1.1_000662 754252.PFREUD_20660 2.6e-74 284.6 Actinobacteria GO:0008150,GO:0010941,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044531,GO:0044532,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0060548,GO:0065007 Bacteria 2EGB2@1,2GT7C@201174,33A2X@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000663 767029.HMPREF9154_0391 3.4e-07 61.2 Actinobacteria Bacteria 2DRBM@1,2GXTD@201174,33B4F@2 NA|NA|NA S TIGRFAM helicase secretion neighborhood TadE-like protein gnl|extdb|FAM14217-p1-1.1_000664 754252.PFREUD_20640 2.3e-38 164.5 Bacteria Bacteria 2DR18@1,339RQ@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000665 754252.PFREUD_20630 2.2e-87 328.2 Actinobacteria Bacteria 2ISXF@201174,COG3381@1,COG3381@2 NA|NA|NA S PFAM cytoplasmic chaperone TorD gnl|extdb|FAM14217-p1-1.1_000666 754252.PFREUD_20620 3.1e-215 754.2 Actinobacteria ko:K18930 ko00000 Bacteria 2GRKW@201174,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM14217-p1-1.1_000668 754252.PFREUD_20600 3e-132 477.6 Propionibacteriales dmsB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009389,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016667,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 ko:K07307,ko:K07311 ko00920,map00920 R09501 RC02555 ko00000,ko00001,ko02000 5.A.3.3 iPC815.YPO3324 Bacteria 2H0W0@201174,4DVEF@85009,COG0437@1,COG0437@2 NA|NA|NA C 4Fe-4S binding domain gnl|extdb|FAM14217-p1-1.1_000669 754252.PFREUD_20590 7.8e-180 636.3 Actinobacteria dmsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009389,GO:0009390,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0055114,GO:0071944,GO:1902494 ko:K07308,ko:K07312 ko00920,map00920 R09501 RC02555 ko00000,ko00001,ko02000 5.A.3.3 iE2348C_1286.E2348C_1674,iECNA114_1301.ECNA114_1636,iECO103_1326.ECO103_1729,iECO111_1330.ECO111_0964,iECO26_1355.ECO26_1022,iECSF_1327.ECSF_1450,iUTI89_1310.UTI89_C0969 Bacteria 2GV8F@201174,COG3302@1,COG3302@2 NA|NA|NA S DMSO reductase anchor subunit (DmsC) gnl|extdb|FAM14217-p1-1.1_000670 754252.PFREUD_20580 0.0 1603.2 Propionibacteriales yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 ko:K06877 ko00000 Bacteria 2GJJ6@201174,4DNQG@85009,COG1205@1,COG1205@2 NA|NA|NA L Domain of unknown function (DUF1998) gnl|extdb|FAM14217-p1-1.1_000671 754252.PFREUD_20570 2.1e-293 1014.2 Propionibacteriales rsmC ko:K00612 ko00000,ko01000 Bacteria 2GJPP@201174,4DNCS@85009,COG2890@1,COG2890@2 NA|NA|NA J Methyltransferase small domain gnl|extdb|FAM14217-p1-1.1_000672 754252.PFREUD_20560 0.0 1699.9 Propionibacteriales topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJU7@201174,4DN7K@85009,COG0550@1,COG0550@2,COG1754@1,COG1754@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone gnl|extdb|FAM14217-p1-1.1_000673 767029.HMPREF9154_2697 1.3e-31 144.4 Bacteria ygiF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.1.25 ko:K18446 ko00000,ko01000 Bacteria COG3025@1,COG3025@2 NA|NA|NA S triphosphatase activity gnl|extdb|FAM14217-p1-1.1_000674 754252.PFREUD_20540 2.3e-116 424.9 Propionibacteriales tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNTI@201174,4DNXP@85009,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis gnl|extdb|FAM14217-p1-1.1_000676 754252.PFREUD_20520 1.4e-115 423.7 Actinobacteria ko:K15977 ko00000 Bacteria 2GV27@201174,COG2259@1,COG2259@2 NA|NA|NA S DoxX gnl|extdb|FAM14217-p1-1.1_000677 754252.PFREUD_20510 8.2e-156 556.6 Actinobacteria tpl Bacteria 2HYDT@201174,COG1774@1,COG1774@2 NA|NA|NA S PFAM PSP1 domain protein gnl|extdb|FAM14217-p1-1.1_000679 754252.PFREUD_20480 2.2e-135 488.4 Actinobacteria ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GK3I@201174,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter gnl|extdb|FAM14217-p1-1.1_000680 754252.PFREUD_20470 3e-167 595.1 Actinobacteria ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMH5@201174,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family gnl|extdb|FAM14217-p1-1.1_000681 754252.PFREUD_20460 7.1e-267 926.0 Actinobacteria cycA ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 Bacteria 2GJ0X@201174,COG1113@1,COG1113@2 NA|NA|NA E amino acid gnl|extdb|FAM14217-p1-1.1_000682 754252.PFREUD_20440 1e-259 902.1 Propionibacteriales 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK23@201174,4DP12@85009,COG1231@1,COG1231@2 NA|NA|NA E amine oxidase gnl|extdb|FAM14217-p1-1.1_000683 710685.MycrhN_2941 6.1e-257 892.9 Mycobacteriaceae Bacteria 237B6@1762,2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L transposase gnl|extdb|FAM14217-p1-1.1_000684 754252.PFREUD_20430 7.2e-53 213.0 Propionibacteriales glnB ko:K04751 ko02020,map02020 ko00000,ko00001 Bacteria 2IKN1@201174,4DR0Z@85009,COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family gnl|extdb|FAM14217-p1-1.1_000685 754252.PFREUD_20420 1.2e-247 862.1 Propionibacteriales amt ko:K03320 ko00000,ko02000 1.A.11 iNJ661.Rv2920c Bacteria 2GIZK@201174,4DNW9@85009,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family gnl|extdb|FAM14217-p1-1.1_000686 754252.PFREUD_20410 5.2e-182 643.7 Bacteria Bacteria COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM14217-p1-1.1_000687 754252.PFREUD_20400 6.4e-165 586.6 Bacteria corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria COG0598@1,COG0598@2 NA|NA|NA P Magnesium transport protein CorA gnl|extdb|FAM14217-p1-1.1_000688 754252.PFREUD_20390 3.2e-95 354.4 Bacteria sixA ko:K08296 ko00000,ko01000 Bacteria COG2062@1,COG2062@2 NA|NA|NA T phosphohistidine phosphatase, SixA gnl|extdb|FAM14217-p1-1.1_000690 754252.PFREUD_20370 4.1e-104 384.0 Propionibacteriales ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 iNJ661.Rv3628 Bacteria 2GM7F@201174,4DQYI@85009,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions gnl|extdb|FAM14217-p1-1.1_000691 754252.PFREUD_20360 3.5e-247 860.5 Propionibacteriales dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2GJPH@201174,4DN2Y@85009,COG2027@1,COG2027@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase gnl|extdb|FAM14217-p1-1.1_000692 754252.PFREUD_20350 1.3e-204 718.8 Propionibacteriales Bacteria 2GJ8E@201174,4DNQY@85009,COG5282@1,COG5282@2 NA|NA|NA S Zincin-like metallopeptidase gnl|extdb|FAM14217-p1-1.1_000693 754252.PFREUD_20340 5.3e-173 613.6 Propionibacteriales tilS GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJR4@201174,4DQ41@85009,COG0037@1,COG0037@2 NA|NA|NA D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine gnl|extdb|FAM14217-p1-1.1_000694 754252.PFREUD_20330 1.9e-95 355.1 Propionibacteriales hpt 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GMDZ@201174,4DN1D@85009,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family gnl|extdb|FAM14217-p1-1.1_000696 754252.PFREUD_20310 1.4e-111 409.1 Propionibacteriales folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iIT341.HP0928 Bacteria 2GP2P@201174,4DN6R@85009,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase gnl|extdb|FAM14217-p1-1.1_000697 754252.PFREUD_20300 5.4e-51 207.2 Propionibacteriales Bacteria 2IQEW@201174,4DRRW@85009,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor gnl|extdb|FAM14217-p1-1.1_000700 754252.PFREUD_20270 3.7e-99 367.5 Propionibacteriales folK 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 Bacteria 2H3G6@201174,4DQ88@85009,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) gnl|extdb|FAM14217-p1-1.1_000702 754252.PFREUD_20260 1.2e-52 212.2 Actinobacteria lsr Bacteria 2C4MW@1,2IQ6A@201174,32RKK@2 NA|NA|NA S pathogenesis gnl|extdb|FAM14217-p1-1.1_000703 754252.PFREUD_20250 0.0 1576.2 Propionibacteriales clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2GJ77@201174,4DPBH@85009,COG0542@1,COG0542@2 NA|NA|NA O C-terminal, D2-small domain, of ClpB protein gnl|extdb|FAM14217-p1-1.1_000705 754252.PFREUD_20230 2e-135 488.4 Actinobacteria aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 Bacteria 2GREB@201174,COG0710@1,COG0710@2 NA|NA|NA E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate gnl|extdb|FAM14217-p1-1.1_000707 754252.PFREUD_20200 2.6e-141 508.1 Actinobacteria cbiQ ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2IDC9@201174,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport gnl|extdb|FAM14217-p1-1.1_000708 754252.PFREUD_20190 3.7e-291 1006.9 Propionibacteriales ykoD ko:K01990,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00254,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4DT5R@85009,COG1122@1,COG1122@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_000712 754252.PFREUD_20150 1.1e-256 892.1 Propionibacteriales radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 2GMQ0@201174,4DNF3@85009,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function gnl|extdb|FAM14217-p1-1.1_000713 754252.PFREUD_20140 3.6e-122 444.1 Propionibacteriales Bacteria 2DC18@1,2IBBW@201174,2ZCCT@2,4DUJG@85009 NA|NA|NA S Glyoxalase-like domain gnl|extdb|FAM14217-p1-1.1_000714 754252.PFREUD_20130 8.7e-164 582.8 Propionibacteriales Bacteria 2GJ6E@201174,4DMZR@85009,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel gnl|extdb|FAM14217-p1-1.1_000715 754252.PFREUD_20120 6.3e-148 530.0 Propionibacteriales ko:K07052 ko00000 Bacteria 2GK11@201174,4DR9W@85009,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM14217-p1-1.1_000716 754252.PFREUD_20110 3.9e-117 427.6 Bacteria Bacteria COG3548@1,COG3548@2 NA|NA|NA S protein homotetramerization gnl|extdb|FAM14217-p1-1.1_000717 754252.PFREUD_20100 1.8e-179 635.2 Propionibacteriales asd GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3708c Bacteria 2GJJ8@201174,4DNGU@85009,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate gnl|extdb|FAM14217-p1-1.1_000718 754252.PFREUD_20090 4.3e-126 457.6 Propionibacteriales proC GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ7D@201174,4DNEJ@85009,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline gnl|extdb|FAM14217-p1-1.1_000720 754252.PFREUD_20070 5.8e-302 1042.7 Propionibacteriales hemD GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 ko:K02302,ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJZ@201174,4DNP0@85009,COG0007@1,COG0007@2,COG1587@1,COG1587@2 NA|NA|NA H Uroporphyrinogen-III synthase HemD gnl|extdb|FAM14217-p1-1.1_000721 754252.PFREUD_20060 1.4e-124 452.2 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 3.1.3.3,3.1.3.73 ko:K02226,ko:K22305 ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130 M00122 R00582,R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMXF@201174,4DPM9@85009,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family gnl|extdb|FAM14217-p1-1.1_000723 754252.PFREUD_20040 2.9e-192 677.9 Propionibacteriales nagZ 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM43@201174,4DQDD@85009,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain gnl|extdb|FAM14217-p1-1.1_000725 754252.PFREUD_20020 6.2e-79 300.1 Actinobacteria arsD Bacteria 2DMHQ@1,2IQ7H@201174,32RMG@2 NA|NA|NA S Arsenical resistance operon trans-acting repressor gnl|extdb|FAM14217-p1-1.1_000726 754252.PFREUD_20010 6.9e-65 253.1 Bacteria ko:K03892 ko00000,ko03000 Bacteria COG0640@1,COG0640@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM14217-p1-1.1_000727 754252.PFREUD_19990 1e-78 299.3 Propionibacteriales arsC 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 2IHR3@201174,4DQUH@85009,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family gnl|extdb|FAM14217-p1-1.1_000728 754252.PFREUD_19980 1e-142 512.7 Propionibacteriales pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria 2GJQ3@201174,4DN0B@85009,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system gnl|extdb|FAM14217-p1-1.1_000729 754252.PFREUD_19970 5.8e-203 713.4 Propionibacteriales pstA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iJN746.PP_2658,iPC815.YPO4115,iYL1228.KPN_04131,iZ_1308.Z5217 Bacteria 2I2F2@201174,4DPD3@85009,COG0581@1,COG0581@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000731 754252.PFREUD_19950 7.1e-187 659.8 Propionibacteriales pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 2GJXD@201174,4DPFF@85009,COG0226@1,COG0226@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import gnl|extdb|FAM14217-p1-1.1_000732 754252.PFREUD_19940 5.7e-166 590.1 Propionibacteriales mutT 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNRV@201174,4DQI9@85009,COG0494@1,COG0494@2 NA|NA|NA L Phosphoglycerate mutase family gnl|extdb|FAM14217-p1-1.1_000734 754252.PFREUD_19920 1.6e-179 635.2 Propionibacteriales mshD GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189,2.7.4.1 ko:K00937,ko:K15520 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GM35@201174,4DQJC@85009,COG0454@1,COG0456@2 NA|NA|NA K Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol gnl|extdb|FAM14217-p1-1.1_000735 754252.PFREUD_19910 3.6e-196 690.6 Propionibacteriales galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMCW@201174,4DQX1@85009,COG1087@1,COG1087@2 NA|NA|NA M Polysaccharide biosynthesis protein gnl|extdb|FAM14217-p1-1.1_000736 754252.PFREUD_19900 3.6e-142 510.8 Bacteria pcaC 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria COG0599@1,COG0599@2,COG1917@1,COG1917@2 NA|NA|NA S peroxiredoxin activity gnl|extdb|FAM14217-p1-1.1_000737 754252.PFREUD_19890 3.2e-136 491.1 Actinobacteria 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 R05066 RC00099 ko00000,ko00001,ko01000 Bacteria 2IE00@201174,COG2084@1,COG2084@2 NA|NA|NA I NAD binding domain of 6-phosphogluconate dehydrogenase gnl|extdb|FAM14217-p1-1.1_000738 754252.PFREUD_19880 5.8e-205 719.9 Propionibacteriales ino1 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 R07324 RC01804 ko00000,ko00001,ko01000 Bacteria 2GKHB@201174,4DNQF@85009,COG1260@1,COG1260@2 NA|NA|NA I Myo-inositol-1-phosphate synthase gnl|extdb|FAM14217-p1-1.1_000739 754252.PFREUD_19870 8.3e-122 443.0 Propionibacteriales Bacteria 2GJGU@201174,4DN15@85009,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal gnl|extdb|FAM14217-p1-1.1_000740 754252.PFREUD_19860 3.2e-74 284.3 Propionibacteriales dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 2IKVR@201174,4DQK6@85009,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality gnl|extdb|FAM14217-p1-1.1_000742 754252.PFREUD_19830 2e-99 368.2 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GKGF@201174,4DQW9@85009,COG4044@1,COG4044@2 NA|NA|NA S May play a role in the intracellular transport of hydrophobic ligands gnl|extdb|FAM14217-p1-1.1_000743 754252.PFREUD_19820 6.4e-201 706.4 Propionibacteriales ygfZ GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GKP0@201174,4DN39@85009,COG0354@1,COG0354@2 NA|NA|NA S Belongs to the GcvT family gnl|extdb|FAM14217-p1-1.1_000744 754252.PFREUD_19810 0.0 1242.6 Propionibacteriales typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 2GJUJ@201174,4DP68@85009,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA gnl|extdb|FAM14217-p1-1.1_000745 754252.PFREUD_19790 0.0 1703.7 Actinobacteria Bacteria 2GJU9@201174,COG4932@1,COG4932@2 NA|NA|NA M domain protein gnl|extdb|FAM14217-p1-1.1_000746 1121020.JIAG01000004_gene2068 2.6e-62 246.1 Micrococcaceae Bacteria 1WBFD@1268,2IE6W@201174,COG4932@1,COG4932@2 NA|NA|NA M Lpxtg-motif cell wall anchor domain protein gnl|extdb|FAM14217-p1-1.1_000747 1283287.KB822575_gene650 1.1e-19 103.2 Actinobacteria Bacteria 2IE6W@201174,COG4932@1,COG4932@2 NA|NA|NA M Lpxtg-motif cell wall anchor domain protein gnl|extdb|FAM14217-p1-1.1_000748 754252.PFREUD_19740 2.7e-174 617.8 Propionibacteriales 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2HUS9@201174,4DVWE@85009,COG3764@1,COG3764@2 NA|NA|NA M Sortase family gnl|extdb|FAM14217-p1-1.1_000749 754252.PFREUD_19730 1.9e-115 421.8 Propionibacteriales upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 Bacteria 2GPJE@201174,4DPRI@85009,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate gnl|extdb|FAM14217-p1-1.1_000754 754252.PFREUD_19680 1.9e-260 904.8 Propionibacteriales ko:K11105 ko00000,ko02000 2.A.36.6 Bacteria 2GJ9B@201174,4DN3N@85009,COG3263@1,COG3263@2 NA|NA|NA P TrkA-C domain gnl|extdb|FAM14217-p1-1.1_000756 1122994.AUFR01000007_gene1021 7.7e-18 97.1 Actinobacteria Bacteria 2E1BJ@1,2GXNF@201174,32WRF@2 NA|NA|NA S LytR cell envelope-related transcriptional attenuator gnl|extdb|FAM14217-p1-1.1_000757 754252.PFREUD_19660 3.2e-59 234.2 Propionibacteriales feoA ko:K04758 ko00000,ko02000 Bacteria 2GX6H@201174,4DVX5@85009,COG1918@1,COG1918@2 NA|NA|NA P FeoA gnl|extdb|FAM14217-p1-1.1_000758 754252.PFREUD_19650 0.0 1204.5 Actinobacteria feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 2GTV2@201174,COG0370@1,COG0370@2 NA|NA|NA P Ferrous iron transport protein B gnl|extdb|FAM14217-p1-1.1_000759 754252.PFREUD_19640 1e-104 386.0 Propionibacteriales ko:K07400 ko00000 Bacteria 2IRPN@201174,4DVEH@85009,COG0694@1,COG0694@2 NA|NA|NA O NifU-like domain gnl|extdb|FAM14217-p1-1.1_000760 754252.PFREUD_19630 4.8e-218 763.5 Propionibacteriales galK 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXI@201174,4DQ3A@85009,COG0153@1,COG0153@2 NA|NA|NA G Belongs to the GHMP kinase family gnl|extdb|FAM14217-p1-1.1_000762 754252.PFREUD_19620 6.7e-180 637.1 Propionibacteriales Bacteria 2GMPZ@201174,4DQTY@85009,COG0515@1,COG0515@2 NA|NA|NA KLT SMART serine threonine protein kinase gnl|extdb|FAM14217-p1-1.1_000763 754252.PFREUD_19610 5.3e-296 1023.1 Propionibacteriales Bacteria 2GJ1J@201174,4DNY6@85009,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM14217-p1-1.1_000764 754252.PFREUD_19600 5.2e-262 909.8 Propionibacteriales pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K05364 ko00550,map00550 R04519 RC00005,RC00049 ko00000,ko00001,ko01011 Bacteria 2GJUQ@201174,4DP0A@85009,COG0768@1,COG0768@2 NA|NA|NA M Penicillin binding protein transpeptidase domain gnl|extdb|FAM14217-p1-1.1_000765 754252.PFREUD_19590 1.5e-253 881.7 Propionibacteriales rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 ko:K03588,ko:K05364,ko:K05837 ko00550,ko04112,map00550,map04112 R04519 RC00005,RC00049 ko00000,ko00001,ko01011,ko02000,ko03036 2.A.103.1 Bacteria 2GJTI@201174,4DPN4@85009,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family gnl|extdb|FAM14217-p1-1.1_000767 754252.PFREUD_19570 4.3e-80 303.9 Actinobacteria fhaB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 Bacteria 2GKA7@201174,COG1716@1,COG1716@2 NA|NA|NA T (FHA) domain gnl|extdb|FAM14217-p1-1.1_000768 754252.PFREUD_19560 1.5e-129 468.8 Propionibacteriales fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GNU2@201174,4DQ6H@85009,COG1716@1,COG1716@2 NA|NA|NA T Protein of unknown function (DUF2662) gnl|extdb|FAM14217-p1-1.1_000769 754252.PFREUD_19550 1e-72 279.3 Propionibacteriales trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8,1.8.1.9 ko:K00384,ko:K03671,ko:K03672 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 Bacteria 2IKP1@201174,4DRIP@85009,COG0526@1,COG0526@2 NA|NA|NA CO Belongs to the thioredoxin family gnl|extdb|FAM14217-p1-1.1_000770 754252.PFREUD_19540 1.9e-236 824.7 Actinobacteria Bacteria 2GMAT@201174,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family gnl|extdb|FAM14217-p1-1.1_000771 754252.PFREUD_19540 4.2e-72 277.7 Actinobacteria Bacteria 2GMAT@201174,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family gnl|extdb|FAM14217-p1-1.1_000773 1194165.CAJF01000037_gene3405 6.4e-10 70.5 Microbacteriaceae Bacteria 2ANEZ@1,2IARS@201174,31DDM@2,4FP0Y@85023 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000774 710685.MycrhN_2941 6.1e-257 892.9 Mycobacteriaceae Bacteria 237B6@1762,2GJK7@201174,COG3464@1,COG3464@2 NA|NA|NA L transposase gnl|extdb|FAM14217-p1-1.1_000775 754252.PFREUD_02920 6.8e-95 353.2 Actinobacteria Bacteria 2GMEN@201174,COG3409@1,COG3409@2 NA|NA|NA M Domain of unknown function (DUF1906) gnl|extdb|FAM14217-p1-1.1_000777 1121372.AULK01000004_gene1399 1.1e-253 882.1 Microbacteriaceae Bacteria 2GJK7@201174,4FM4P@85023,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_000778 754252.PFREUD_19510 8.6e-204 716.1 Actinobacteria Bacteria 2ANEZ@1,2IARS@201174,31DDM@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000779 754252.PFREUD_19500 1.2e-238 832.0 Bacteria Bacteria COG5542@1,COG5542@2 NA|NA|NA O integral membrane protein gnl|extdb|FAM14217-p1-1.1_000781 754252.PFREUD_19480 1.8e-38 164.9 Bacteria ptsH 2.7.1.202,2.7.3.9 ko:K02768,ko:K08483,ko:K11183,ko:K11189 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 Bacteria COG1925@1,COG1925@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system gnl|extdb|FAM14217-p1-1.1_000782 754252.PFREUD_19470 8.6e-307 1058.9 Propionibacteriales ptsI 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 Bacteria 2GIZZ@201174,4DPJ6@85009,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) gnl|extdb|FAM14217-p1-1.1_000783 754252.PFREUD_19460 5.7e-61 240.0 Propionibacteriales hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.23,5.4.99.24 ko:K04762,ko:K06179,ko:K06180 ko00000,ko01000,ko03009,ko03110 Bacteria 2IQ6F@201174,4DV0F@85009,COG1188@1,COG1188@2 NA|NA|NA J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) gnl|extdb|FAM14217-p1-1.1_000784 754252.PFREUD_19450 4.6e-131 473.8 Propionibacteriales Bacteria 2GKG9@201174,4DQJF@85009,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain gnl|extdb|FAM14217-p1-1.1_000785 754252.PFREUD_19440 2.7e-137 494.6 Propionibacteriales nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ01@201174,4DNJN@85009,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate gnl|extdb|FAM14217-p1-1.1_000786 754252.PFREUD_19430 1.7e-73 282.0 Propionibacteriales yabJ Bacteria 2IHNE@201174,4DQIS@85009,COG0251@1,COG0251@2 NA|NA|NA J YjgF/chorismate_mutase-like, putative endoribonuclease gnl|extdb|FAM14217-p1-1.1_000787 1171373.PACID_29150 1.6e-17 94.7 Propionibacteriales Bacteria 2E3JZ@1,2GQIX@201174,32YI8@2,4DS7G@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000788 754252.PFREUD_19410 4.4e-59 233.8 Propionibacteriales whiB4 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0030312,GO:0043254,GO:0044087,GO:0044464,GO:0047134,GO:0048037,GO:0050789,GO:0050794,GO:0051128,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071944,GO:0090034,GO:0097159,GO:1901363 ko:K18955 ko00000,ko03000 Bacteria 2CC1Y@1,2IQEP@201174,32TCV@2,4DRQS@85009 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA gnl|extdb|FAM14217-p1-1.1_000789 754252.PFREUD_19400 0.0 1432.9 Propionibacteriales pon1 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4DPA4@85009,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase gnl|extdb|FAM14217-p1-1.1_000792 754252.PFREUD_19370 2.8e-290 1003.8 Bacteria 2.4.1.12 ko:K00694,ko:K00786 ko00500,ko01100,ko02026,map00500,map01100,map02026 R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria COG1215@1,COG1215@2 NA|NA|NA M transferase activity, transferring glycosyl groups gnl|extdb|FAM14217-p1-1.1_000795 754252.PFREUD_19350 1.5e-262 911.8 Propionibacteriales 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJ4@201174,4DNWA@85009,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase gnl|extdb|FAM14217-p1-1.1_000797 1285583.CCASEI_12085 1.4e-32 146.4 Corynebacteriaceae ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567 ko00000,ko01000,ko03400 Bacteria 22RBI@1653,2IHXW@201174,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated gnl|extdb|FAM14217-p1-1.1_000799 754252.PFREUD_19310 1.1e-186 659.1 Actinobacteria iunH 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 2GP6N@201174,COG1957@1,COG1957@2 NA|NA|NA F nucleoside hydrolase gnl|extdb|FAM14217-p1-1.1_000800 754252.PFREUD_19300 7.8e-285 985.7 Propionibacteriales aldA 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4DNGV@85009,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM14217-p1-1.1_000802 754252.PFREUD_19280 2e-252 877.9 Propionibacteriales purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMP4@201174,4DNMU@85009,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP gnl|extdb|FAM14217-p1-1.1_000803 754252.PFREUD_19270 1.9e-252 878.2 Propionibacteriales ko:K03294,ko:K03758 ko00000,ko02000 2.A.3.2 Bacteria 2GMTD@201174,4DQSQ@85009,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM14217-p1-1.1_000804 754252.PFREUD_19260 1.4e-264 918.3 Propionibacteriales 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2HBVS@201174,4DU4P@85009,COG0001@1,COG0001@2 NA|NA|NA H Aminotransferase class-III gnl|extdb|FAM14217-p1-1.1_000805 754252.PFREUD_19250 0.0 1611.3 Propionibacteriales clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2GJ73@201174,4DN44@85009,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE gnl|extdb|FAM14217-p1-1.1_000806 754252.PFREUD_19240 0.0 1196.8 Actinobacteria oliA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 Bacteria 2I9UD@201174,COG1297@1,COG1297@2 NA|NA|NA S oligopeptide transporter opt family gnl|extdb|FAM14217-p1-1.1_000807 754252.PFREUD_19230 6.7e-178 629.8 Propionibacteriales speE 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN8I@201174,4DQ70@85009,COG0421@1,COG0421@2 NA|NA|NA E spermidine synthase gnl|extdb|FAM14217-p1-1.1_000808 754252.PFREUD_19210 9.1e-107 392.9 Bacteria srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria COG3764@1,COG3764@2 NA|NA|NA M Sortase family gnl|extdb|FAM14217-p1-1.1_000809 754252.PFREUD_19200 7.3e-95 353.2 Actinobacteria pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 iJN678.umpS Bacteria 2GKUQ@201174,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) gnl|extdb|FAM14217-p1-1.1_000814 754252.PFREUD_19150 3.3e-194 684.1 Propionibacteriales fbaA GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z4263 Bacteria 2GM5P@201174,4DPKE@85009,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class II gnl|extdb|FAM14217-p1-1.1_000816 754252.PFREUD_19130 5.5e-214 750.0 Actinobacteria 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 2GM8C@201174,COG1062@1,COG1062@2 NA|NA|NA C alcohol dehydrogenase gnl|extdb|FAM14217-p1-1.1_000817 754252.PFREUD_19120 4.1e-173 614.4 Actinobacteria Bacteria 2DYWR@1,2I6UH@201174,34BGI@2 NA|NA|NA S Sugar (and other) transporter gnl|extdb|FAM14217-p1-1.1_000818 754252.PFREUD_19110 3.3e-297 1026.9 Actinobacteria araP ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.26 Bacteria 2I77C@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM14217-p1-1.1_000819 754252.PFREUD_19100 1.1e-291 1008.4 Propionibacteriales mmsA 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJI2@201174,4DNVW@85009,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family gnl|extdb|FAM14217-p1-1.1_000820 754252.PFREUD_19090 0.0 1259.2 Propionibacteriales iolD GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 R08603 RC02331 ko00000,ko00001,ko01000 iYO844.BSU39730 Bacteria 2GMCJ@201174,4DQ59@85009,COG3962@1,COG3962@2 NA|NA|NA E Thiamine pyrophosphate enzyme, central domain gnl|extdb|FAM14217-p1-1.1_000821 754252.PFREUD_19080 1.5e-174 618.6 Propionibacteriales iolB 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 R08503 RC00541 ko00000,ko00001,ko01000 Bacteria 2GM8S@201174,4DQKK@85009,COG3718@1,COG3718@2 NA|NA|NA G KduI/IolB family gnl|extdb|FAM14217-p1-1.1_000822 754252.PFREUD_19070 6.6e-159 566.6 Propionibacteriales Bacteria 2GKTN@201174,4DN9P@85009,COG1830@1,COG1830@2 NA|NA|NA G deoxyribose-phosphate aldolase gnl|extdb|FAM14217-p1-1.1_000823 754252.PFREUD_19060 4.2e-186 657.1 Propionibacteriales iolC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 R05661 RC00002,RC00017 ko00000,ko00001,ko01000 iYO844.BSU39740 Bacteria 2GM3N@201174,4DNFD@85009,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM14217-p1-1.1_000824 754252.PFREUD_19050 9.8e-135 486.1 Propionibacteriales yegW ko:K03710 ko00000,ko03000 Bacteria 2GJZ1@201174,4DQMB@85009,COG2188@1,COG2188@2 NA|NA|NA K UTRA gnl|extdb|FAM14217-p1-1.1_000825 754252.PFREUD_19040 1.9e-203 714.9 Propionibacteriales tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMF9@201174,4DTCS@85009,COG0176@1,COG0176@2 NA|NA|NA H Transaldolase/Fructose-6-phosphate aldolase gnl|extdb|FAM14217-p1-1.1_000826 754252.PFREUD_19030 6.3e-182 643.3 Propionibacteriales idhA 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2GJCY@201174,4DUJU@85009,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain gnl|extdb|FAM14217-p1-1.1_000828 754252.PFREUD_19010 1.6e-179 635.2 Actinobacteria iolE 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 iECED1_1282.ECED1_0303 Bacteria 2GJKJ@201174,COG1082@1,COG1082@2 NA|NA|NA G dehydratase gnl|extdb|FAM14217-p1-1.1_000830 754252.PFREUD_18990 0.0 1216.8 Propionibacteriales ilvD GO:0003674,GO:0003824,GO:0004160,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1259,iECIAI39_1322.ECIAI39_3015 Bacteria 2GJIJ@201174,4DN1H@85009,COG0129@1,COG0129@2 NA|NA|NA EG Belongs to the IlvD Edd family gnl|extdb|FAM14217-p1-1.1_000831 754252.PFREUD_18980 0.0 1320.4 Propionibacteriales asnB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJIM@201174,4DQH7@85009,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase gnl|extdb|FAM14217-p1-1.1_000832 754252.PFREUD_18970 1.5e-225 788.5 Propionibacteriales hemA GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 ko:K02407,ko:K02492 ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000,ko02035 iSB619.SA_RS08420 Bacteria 2GJRA@201174,4DPDT@85009,COG0373@1,COG0373@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) gnl|extdb|FAM14217-p1-1.1_000835 754252.PFREUD_18940 7.3e-219 766.1 Actinobacteria pqqE ko:K22227 ko00000 Bacteria 2GNSY@201174,COG0535@1,COG0535@2 NA|NA|NA C Radical SAM gnl|extdb|FAM14217-p1-1.1_000836 754252.PFREUD_18930 1.5e-278 964.9 Actinobacteria hemG 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMMA@201174,COG1232@1,COG1232@2 NA|NA|NA H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX gnl|extdb|FAM14217-p1-1.1_000837 754252.PFREUD_18920 5e-201 706.8 Propionibacteriales hemH GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJTQ@201174,4DNBP@85009,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX gnl|extdb|FAM14217-p1-1.1_000838 754252.PFREUD_18910 8.9e-184 649.4 Propionibacteriales hemB GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 iECABU_c1320.ECABU_c04500,iEcSMS35_1347.EcSMS35_0398,iJN746.PP_2913,ic_1306.c0477 Bacteria 2GJJ0@201174,4DNVG@85009,COG0113@1,COG0113@2 NA|NA|NA H Belongs to the ALAD family gnl|extdb|FAM14217-p1-1.1_000839 754252.PFREUD_18900 7.5e-232 809.7 Propionibacteriales Bacteria 2GIZX@201174,4DPB8@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000841 754252.PFREUD_18880 1e-248 865.5 Propionibacteriales hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158 Bacteria 2GJSH@201174,4DNRS@85009,COG0001@1,COG0001@2 NA|NA|NA H Glutamate-1-semialdehyde aminotransferase gnl|extdb|FAM14217-p1-1.1_000842 754252.PFREUD_18870 4.8e-290 1003.0 Propionibacteriales oadA 2.1.3.1,4.1.1.3,6.4.1.1 ko:K01571,ko:K01960,ko:K03416 ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00217,R00344,R00353,R00930 RC00040,RC00097,RC00367 ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 iLJ478.TM0128 Bacteria 2IASR@201174,4DWP2@85009,COG5016@1,COG5016@2 NA|NA|NA C Conserved carboxylase domain gnl|extdb|FAM14217-p1-1.1_000843 754252.PFREUD_18860 2.9e-298 1030.4 Actinobacteria mmdA 2.1.3.1,2.1.3.15,6.4.1.3 ko:K01966,ko:K17489 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R00353,R01859 RC00040,RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0716 Bacteria 2GIRU@201174,COG4799@1,COG4799@2 NA|NA|NA I Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta gnl|extdb|FAM14217-p1-1.1_000844 1292373.H640_07489 8.4e-19 99.4 Bacteria 2.1.3.1 ko:K17489 ko00640,map00640 R00353 RC00040 ko00000,ko00001,ko01000 Bacteria 2EJZC@1,33DPX@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000845 754252.PFREUD_18840 4.8e-10 70.9 Bacteria yngHB 2.1.3.1,6.4.1.1 ko:K01958,ko:K02160,ko:K17490 ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230 M00082,M00173,M00376 R00344,R00353,R00742 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria COG1038@1,COG1038@2 NA|NA|NA C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second gnl|extdb|FAM14217-p1-1.1_000846 754252.PFREUD_18830 9e-133 479.6 Propionibacteriales Bacteria 2GMGQ@201174,4DPFM@85009,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM14217-p1-1.1_000847 754252.PFREUD_18820 2.1e-134 485.0 Propionibacteriales Bacteria 2HFX1@201174,4DRU7@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial transcriptional repressor C-terminal gnl|extdb|FAM14217-p1-1.1_000848 754252.PFREUD_18810 3.3e-143 514.2 Propionibacteriales gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GK8F@201174,4DND2@85009,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gnl|extdb|FAM14217-p1-1.1_000849 754252.PFREUD_18800 3.6e-120 437.6 Propionibacteriales phoU ko:K02039 ko00000 Bacteria 2GKAD@201174,4DQEB@85009,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake gnl|extdb|FAM14217-p1-1.1_000851 754252.PFREUD_18780 2.1e-120 438.3 Propionibacteriales Bacteria 2GKFS@201174,4DNN6@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM14217-p1-1.1_000852 754252.PFREUD_18770 1.4e-81 308.9 Propionibacteriales carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K07736 ko00000,ko03000 Bacteria 2GKSU@201174,4DN6V@85009,COG1329@1,COG1329@2 NA|NA|NA K CarD-like/TRCF domain gnl|extdb|FAM14217-p1-1.1_000853 754252.PFREUD_18760 2.6e-132 478.0 Propionibacteriales ispD GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNHP@201174,4DS1C@85009,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) gnl|extdb|FAM14217-p1-1.1_000855 754252.PFREUD_18740 6.9e-278 962.6 Propionibacteriales glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK7U@201174,4DPXC@85009,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism gnl|extdb|FAM14217-p1-1.1_000856 754252.PFREUD_18730 5.6e-186 656.8 Bacteria ansA GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0033345,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 iECO103_1326.ECO103_1961,iSF_1195.SF1456,iS_1188.S1571,iYL1228.KPN_01203 Bacteria COG0252@1,COG0252@2 NA|NA|NA EJ asparaginase activity gnl|extdb|FAM14217-p1-1.1_000857 754252.PFREUD_18720 5.1e-276 956.4 Propionibacteriales ko:K03293,ko:K11738 ko00000,ko02000 2.A.3.1,2.A.3.1.8 Bacteria 2GJ0X@201174,4DTIR@85009,COG1113@1,COG1113@2 NA|NA|NA E COG1113 Gamma-aminobutyrate permease and related permeases gnl|extdb|FAM14217-p1-1.1_000858 754252.PFREUD_18700 2.9e-279 967.2 Propionibacteriales ko:K03293,ko:K11738 ko00000,ko02000 2.A.3.1,2.A.3.1.8 Bacteria 2GJ0X@201174,4DTIR@85009,COG1113@1,COG1113@2 NA|NA|NA E COG1113 Gamma-aminobutyrate permease and related permeases gnl|extdb|FAM14217-p1-1.1_000859 754252.PFREUD_18690 9.1e-167 592.8 Propionibacteriales rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJMR@201174,4DNYC@85009,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gnl|extdb|FAM14217-p1-1.1_000860 754252.PFREUD_18680 2.4e-280 970.7 Propionibacteriales cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJF2@201174,4DP8C@85009,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family gnl|extdb|FAM14217-p1-1.1_000862 754252.PFREUD_18660 2e-308 1064.3 Propionibacteriales ko:K03303 ko00000,ko02000 2.A.14 Bacteria 2GIUF@201174,4DPUA@85009,COG1620@1,COG1620@2 NA|NA|NA C L-lactate permease gnl|extdb|FAM14217-p1-1.1_000863 754252.PFREUD_18650 5.9e-154 550.1 Propionibacteriales lutA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K18928 ko00000 iEC042_1314.EC042_0340,iEcSMS35_1347.EcSMS35_0338 Bacteria 2GIVX@201174,4DNWX@85009,COG0247@1,COG0247@2 NA|NA|NA C Cysteine-rich domain gnl|extdb|FAM14217-p1-1.1_000864 754252.PFREUD_18640 5e-295 1019.6 Propionibacteriales lutB ko:K18929 ko00000 Bacteria 2GJDR@201174,4DQ12@85009,COG0247@1,COG0247@2,COG1139@1,COG1139@2 NA|NA|NA C LUD domain gnl|extdb|FAM14217-p1-1.1_000865 754252.PFREUD_18630 6.8e-116 423.3 Propionibacteriales ko:K00782,ko:K18929 ko00000 Bacteria 2GNUJ@201174,4DRME@85009,COG1556@1,COG1556@2 NA|NA|NA S LUD domain gnl|extdb|FAM14217-p1-1.1_000867 754252.PFREUD_18600 2.3e-267 927.5 Propionibacteriales inaA ko:K02848 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2GIX0@201174,4DNTH@85009,COG3642@1,COG3642@2 NA|NA|NA T Domain of unknown function (DUF4032) gnl|extdb|FAM14217-p1-1.1_000868 754252.PFREUD_18590 3.1e-220 770.8 Propionibacteriales metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 iAF1260.b3939,iBWG_1329.BWG_3608,iECDH10B_1368.ECDH10B_4128,iECDH1ME8569_1439.ECDH1ME8569_3808,iETEC_1333.ETEC_4208,iEcDH1_1363.EcDH1_4046,iEcHS_1320.EcHS_A4172,iEcolC_1368.EcolC_4076,iJO1366.b3939,iJR904.b3939,iUMNK88_1353.UMNK88_4777,iUTI89_1310.UTI89_C4524,iY75_1357.Y75_RS17365 Bacteria 2GJ5S@201174,4DNK6@85009,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme gnl|extdb|FAM14217-p1-1.1_000869 754252.PFREUD_18580 1.4e-203 715.3 Propionibacteriales msiK ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 2GJCM@201174,4DN4V@85009,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily gnl|extdb|FAM14217-p1-1.1_000870 754252.PFREUD_18570 3.9e-270 936.8 Propionibacteriales sdaAB GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 2GJPA@201174,4DPVP@85009,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain gnl|extdb|FAM14217-p1-1.1_000872 754252.PFREUD_18550 9.7e-151 539.7 Propionibacteriales Bacteria 2IP88@201174,4DVGS@85009,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein gnl|extdb|FAM14217-p1-1.1_000873 754252.PFREUD_18540 1.8e-87 328.6 Propionibacteriales ymdB Bacteria 2IFEC@201174,4DR0K@85009,COG2110@1,COG2110@2 NA|NA|NA S Appr-1'-p processing enzyme gnl|extdb|FAM14217-p1-1.1_000874 754252.PFREUD_18530 3.4e-59 234.2 Actinobacteria Bacteria 2AHT8@1,2IMSB@201174,3185S@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000875 754252.PFREUD_18520 0.0 1223.4 Bacteria kch Bacteria COG1226@1,COG1226@2 NA|NA|NA P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) gnl|extdb|FAM14217-p1-1.1_000878 754252.PFREUD_18490 2.3e-231 807.7 Propionibacteriales manA GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,5.3.1.8,5.4.2.8 ko:K01809,ko:K01840,ko:K04035 ko00051,ko00520,ko00860,ko01100,ko01110,ko01130,map00051,map00520,map00860,map01100,map01110,map01130 M00114 R01818,R01819,R06265,R06266,R06267,R10068 RC00376,RC00408,RC00741,RC01491,RC01492,RC03042 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801 Bacteria 2GJXC@201174,4DPWV@85009,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase, class I gnl|extdb|FAM14217-p1-1.1_000879 1203605.HMPREF1531_00302 9.9e-24 115.9 Actinobacteria Bacteria 2CUM0@1,2IQG7@201174,32SVJ@2 NA|NA|NA S Protein of unknown function (DUF3263) gnl|extdb|FAM14217-p1-1.1_000880 754252.PFREUD_18470 8.8e-290 1002.3 Propionibacteriales groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2GKC9@201174,4DNNQ@85009,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions gnl|extdb|FAM14217-p1-1.1_000884 754252.PFREUD_18300 1.5e-103 382.1 Propionibacteriales 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2HZ8R@201174,4DR5X@85009,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain gnl|extdb|FAM14217-p1-1.1_000885 754252.PFREUD_18290 1.6e-310 1071.2 Actinobacteria Bacteria 2GQDQ@201174,COG1404@1,COG1404@2 NA|NA|NA O S-layer domain protein gnl|extdb|FAM14217-p1-1.1_000887 754252.PFREUD_18260 4e-08 65.9 Bacteria Bacteria COG5479@1,COG5479@2 NA|NA|NA M isomerase activity gnl|extdb|FAM14217-p1-1.1_000889 1121933.AUHH01000001_gene2207 2.9e-243 847.8 Propionibacteriales ercc3 3.6.4.12 ko:K10843 ko03022,ko03420,map03022,map03420 M00290 ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GIR9@201174,4DNIW@85009,COG1061@1,COG1061@2 NA|NA|NA L ERCC3/RAD25/XPB C-terminal helicase gnl|extdb|FAM14217-p1-1.1_000890 754252.PFREUD_18230 0.0 1377.8 Propionibacteriales Bacteria 2GURQ@201174,4DP0U@85009,COG2378@1,COG2378@2 NA|NA|NA K Helicase conserved C-terminal domain gnl|extdb|FAM14217-p1-1.1_000892 754252.PFREUD_18210 1.3e-66 258.8 Propionibacteriales cspB ko:K03704 ko00000,ko03000 Bacteria 2IKXN@201174,4DQZ2@85009,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain gnl|extdb|FAM14217-p1-1.1_000893 754252.PFREUD_18200 4.5e-151 540.4 Propionibacteriales Bacteria 28NWB@1,2GJ74@201174,2ZBU7@2,4DQ8F@85009 NA|NA|NA S Protein of unknown function (DUF3027) gnl|extdb|FAM14217-p1-1.1_000894 1292373.H640_07749 1.2e-07 62.8 Bacteria Bacteria 2DCEY@1,2ZDVV@2 NA|NA|NA S Protein of unknown function (DUF2530) gnl|extdb|FAM14217-p1-1.1_000895 754252.PFREUD_18180 4.8e-277 959.9 Propionibacteriales yjcD GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015208,GO:0015851,GO:0015854,GO:0016020,GO:0022857,GO:0035344,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098657,GO:0098710,GO:0098739,GO:1903716,GO:1904823 ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 2GKYD@201174,4DNIA@85009,COG2252@1,COG2252@2 NA|NA|NA S Permease family gnl|extdb|FAM14217-p1-1.1_000897 754252.PFREUD_18160 1.7e-215 755.0 Propionibacteriales serC GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKYK@201174,4DP4I@85009,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine gnl|extdb|FAM14217-p1-1.1_000898 754252.PFREUD_18150 8.2e-125 453.0 Propionibacteriales ideR ko:K03709 ko00000,ko03000 Bacteria 2GKMC@201174,4DP20@85009,COG1321@1,COG1321@2 NA|NA|NA K Helix-turn-helix diphteria tox regulatory element gnl|extdb|FAM14217-p1-1.1_000899 754252.PFREUD_18140 8.1e-57 226.1 Propionibacteriales trx 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 2I2FB@201174,4DWYI@85009,COG3118@1,COG3118@2 NA|NA|NA O Thioredoxin gnl|extdb|FAM14217-p1-1.1_000900 754252.PFREUD_18120 2.6e-61 241.1 Bacteria Bacteria 2E4BT@1,33YQ0@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000901 754252.PFREUD_18110 1.1e-155 555.8 Bacteria Bacteria COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity gnl|extdb|FAM14217-p1-1.1_000902 754252.PFREUD_18100 2.6e-109 401.4 Propionibacteriales ycaC Bacteria 2GKZR@201174,4DSEZ@85009,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family gnl|extdb|FAM14217-p1-1.1_000905 754252.PFREUD_18070 5.2e-267 926.4 Propionibacteriales ugpA 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2G3@201174,4DPKI@85009,COG4284@1,COG4284@2 NA|NA|NA G UTP--glucose-1-phosphate uridylyltransferase gnl|extdb|FAM14217-p1-1.1_000906 767029.HMPREF9154_2601 1e-07 62.8 Bacteria Bacteria 2DDCJ@1,2ZHHZ@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000908 754252.PFREUD_18030 7.8e-93 346.7 Bacteria cpaB ko:K02279 ko00000,ko02035,ko02044 Bacteria COG3745@1,COG3745@2 NA|NA|NA U Flp pilus assembly protein CpaB gnl|extdb|FAM14217-p1-1.1_000910 754252.PFREUD_18010 1.9e-105 388.7 Propionibacteriales fthC 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 2IKWR@201174,4DR3Y@85009,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family gnl|extdb|FAM14217-p1-1.1_000911 754252.PFREUD_18000 4.3e-231 807.0 Propionibacteriales moeA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 2GJC3@201174,4DNAW@85009,COG0303@1,COG0303@2 NA|NA|NA H MoeA domain protein domain I and II gnl|extdb|FAM14217-p1-1.1_000912 754252.PFREUD_17990 7.1e-127 459.9 Propionibacteriales rimJ 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 2HAFI@201174,4DQM3@85009,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM14217-p1-1.1_000913 1122994.AUFR01000027_gene93 8.4e-76 290.4 Propionibacteriales Bacteria 2ETNC@1,2GKI3@201174,33M63@2,4DS5B@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000916 754252.PFREUD_17940 7.1e-74 283.1 Actinobacteria GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 2IHQV@201174,COG3118@1,COG3118@2 NA|NA|NA O Thioredoxin gnl|extdb|FAM14217-p1-1.1_000919 55952.BU52_27630 4.2e-08 65.5 Actinobacteria Bacteria 2I1C1@201174,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein gnl|extdb|FAM14217-p1-1.1_000920 754252.PFREUD_17900 6.8e-159 566.6 Propionibacteriales vsrA 2.7.13.1,2.7.13.3 ko:K05962,ko:K07675 ko02020,map02020 M00473 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2HDZV@201174,4DNMP@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM14217-p1-1.1_000921 754252.PFREUD_17890 5e-119 433.7 Propionibacteriales ko:K02282 ko00000,ko02035,ko02044 Bacteria 2GJHH@201174,4DQ2F@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM14217-p1-1.1_000924 754252.PFREUD_17840 0.0 1163.3 Propionibacteriales dnaK ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2GJTY@201174,4DP1V@85009,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein gnl|extdb|FAM14217-p1-1.1_000925 754252.PFREUD_17830 5.5e-98 363.6 Actinobacteria grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K02652,ko:K03687 ko00000,ko02035,ko02044,ko03029,ko03110 3.A.15.2 Bacteria 2GP4F@201174,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ gnl|extdb|FAM14217-p1-1.1_000926 754252.PFREUD_17820 1.2e-181 642.5 Propionibacteriales dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2GJKK@201174,4DNFB@85009,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins gnl|extdb|FAM14217-p1-1.1_000927 754252.PFREUD_17810 1e-69 269.2 Bacteria racA ko:K11686,ko:K13640,ko:K18997 ko00000,ko03000,ko03036 Bacteria COG0789@1,COG0789@2 NA|NA|NA K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding gnl|extdb|FAM14217-p1-1.1_000928 1120947.ATUX01000005_gene1507 5.8e-13 80.5 Bacteria rhaS 3.2.2.21 ko:K02854,ko:K02855,ko:K13529,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria COG2169@1,COG2169@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM14217-p1-1.1_000931 754252.PFREUD_17770 2.2e-94 351.7 Actinobacteria Bacteria 28PR5@1,2GTWC@201174,2ZCD3@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000932 754252.PFREUD_17760 4.8e-186 657.1 Propionibacteriales Bacteria 2GKV2@201174,4DVA2@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM14217-p1-1.1_000933 754252.PFREUD_17750 2.5e-102 378.3 Propionibacteriales Bacteria 2HF6M@201174,4DUWR@85009,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon gnl|extdb|FAM14217-p1-1.1_000934 754252.PFREUD_17740 1.6e-135 488.8 Bacteria Bacteria 2A730@1,30VYI@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000935 1209984.BN978_03984 2.5e-106 392.1 Actinobacteria Bacteria 2GY6R@201174,COG0775@1,COG0775@2 NA|NA|NA F SEFIR domain gnl|extdb|FAM14217-p1-1.1_000936 754252.PFREUD_17710 3.2e-63 247.7 Actinobacteria Bacteria 2I9IY@201174,COG0739@1,COG0739@2 NA|NA|NA M peptidase gnl|extdb|FAM14217-p1-1.1_000937 754252.PFREUD_17700 1.4e-65 255.4 Propionibacteriales gloA Bacteria 2IHNJ@201174,4DVAQ@85009,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase-like domain gnl|extdb|FAM14217-p1-1.1_000939 754252.PFREUD_17680 4e-50 203.8 Actinobacteria GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 Bacteria 2GSCM@201174,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor gnl|extdb|FAM14217-p1-1.1_000940 754252.PFREUD_17670 3.6e-255 887.1 Actinobacteria Bacteria 2H4H5@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000941 754252.PFREUD_17660 1.5e-264 918.3 Propionibacteriales proP ko:K03761,ko:K03762 ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 Bacteria 2GIYR@201174,4DPQY@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM14217-p1-1.1_000942 754252.PFREUD_17650 8.6e-102 376.3 Bacteria Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000943 754252.PFREUD_17620 1.5e-203 715.7 Propionibacteriales Bacteria 2GKQH@201174,4DWWP@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000945 754252.PFREUD_17600 3.9e-89 334.0 Actinobacteria ysnE ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GNNG@201174,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM14217-p1-1.1_000947 754252.PFREUD_17580 1.2e-70 272.3 Propionibacteriales crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2IKM1@201174,4DSBC@85009,COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity gnl|extdb|FAM14217-p1-1.1_000948 754252.PFREUD_17570 6.3e-96 356.7 Actinobacteria 2.4.1.266 ko:K13693 ko00000,ko01000,ko01003 GT81 Bacteria 2GUPR@201174,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family gnl|extdb|FAM14217-p1-1.1_000949 754252.PFREUD_17560 4e-223 780.4 Propionibacteriales galK 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXI@201174,4DQ3A@85009,COG0153@1,COG0153@2 NA|NA|NA G Belongs to the GHMP kinase family gnl|extdb|FAM14217-p1-1.1_000950 754252.PFREUD_17540 2.6e-94 351.3 Actinobacteria Bacteria 2H7KC@201174,COG4297@1,COG4297@2 NA|NA|NA S protein containing double-stranded beta helix domain gnl|extdb|FAM14217-p1-1.1_000951 754252.PFREUD_17530 6.4e-290 1002.7 Propionibacteriales rutG GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082 ko:K02824,ko:K09016 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.1.3 iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189 Bacteria 2GMH6@201174,4DP9E@85009,COG2233@1,COG2233@2 NA|NA|NA F Permease family gnl|extdb|FAM14217-p1-1.1_000952 754252.PFREUD_17520 2.9e-185 654.4 Actinobacteria Bacteria 2GMGZ@201174,COG1434@1,COG1434@2 NA|NA|NA V DUF218 domain gnl|extdb|FAM14217-p1-1.1_000954 754252.PFREUD_17500 0.0 1488.8 Actinobacteria 3.2.1.51 ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 GH95 Bacteria 2GJXJ@201174,COG1554@1,COG1554@2 NA|NA|NA G Glycosyl hydrolase family 65, N-terminal domain gnl|extdb|FAM14217-p1-1.1_000955 754252.PFREUD_17490 6.9e-156 556.6 Propionibacteriales rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 2GJ9Q@201174,4DN3D@85009,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA gnl|extdb|FAM14217-p1-1.1_000956 754252.PFREUD_17480 3.1e-192 677.6 Propionibacteriales tatD ko:K03424 ko00000,ko01000 Bacteria 2GMJJ@201174,4DPJ5@85009,COG0084@1,COG0084@2 NA|NA|NA L TatD related DNase gnl|extdb|FAM14217-p1-1.1_000957 754252.PFREUD_17470 2.5e-150 538.1 Propionibacteriales ksgA 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 2GKBT@201174,4DN5S@85009,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits gnl|extdb|FAM14217-p1-1.1_000958 754252.PFREUD_17460 5.6e-167 593.6 Propionibacteriales ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 2GKXD@201174,4DPS0@85009,COG1947@1,COG1947@2 NA|NA|NA I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol gnl|extdb|FAM14217-p1-1.1_000959 754252.PFREUD_17450 3.5e-138 497.7 Actinobacteria icaR Bacteria 2GMBW@201174,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000960 754252.PFREUD_17440 2.6e-194 684.5 Actinobacteria pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z5856 Bacteria 2GKNA@201174,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family gnl|extdb|FAM14217-p1-1.1_000963 754252.PFREUD_17400 4.5e-188 663.7 Propionibacteriales prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ9S@201174,4DP73@85009,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) gnl|extdb|FAM14217-p1-1.1_000964 754252.PFREUD_17390 1.1e-94 352.8 Propionibacteriales ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2GJPJ@201174,4DQEY@85009,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance gnl|extdb|FAM14217-p1-1.1_000965 754252.PFREUD_17370 1.2e-108 399.1 Propionibacteriales pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 2GKCV@201174,4DPFB@85009,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis gnl|extdb|FAM14217-p1-1.1_000966 754252.PFREUD_17360 1.2e-53 215.7 Bacteria ko:K09117 ko00000 Bacteria COG1610@1,COG1610@2 NA|NA|NA S carbon-nitrogen ligase activity, with glutamine as amido-N-donor gnl|extdb|FAM14217-p1-1.1_000967 754252.PFREUD_17350 0.0 2365.9 Propionibacteriales mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ42@201174,4DNWF@85009,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site gnl|extdb|FAM14217-p1-1.1_000968 754252.PFREUD_17340 3.6e-91 340.9 Actinobacteria ppiD 5.2.1.8 ko:K03770,ko:K07533 ko00000,ko01000,ko03110 Bacteria 2ICFD@201174,COG0760@1,COG0760@2 NA|NA|NA O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation gnl|extdb|FAM14217-p1-1.1_000969 754252.PFREUD_17330 6.7e-119 433.3 Propionibacteriales mazG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 Bacteria 2GNKC@201174,4DV8P@85009,COG1694@1,COG3956@2 NA|NA|NA S MazG nucleotide pyrophosphohydrolase domain gnl|extdb|FAM14217-p1-1.1_000970 754252.PFREUD_17320 3.6e-238 830.5 Propionibacteriales eno 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2GJAY@201174,4DPWS@85009,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis gnl|extdb|FAM14217-p1-1.1_000971 754252.PFREUD_17310 6.3e-64 250.8 Propionibacteriales divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 2GQH7@201174,4DS5K@85009,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator gnl|extdb|FAM14217-p1-1.1_000972 754252.PFREUD_17300 9.8e-94 349.4 Propionibacteriales ppx2 3.6.1.11,3.6.1.40 ko:K01524,ko:K09009 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2I8CS@201174,4DQUA@85009,COG1507@1,COG1507@2 NA|NA|NA S Protein of unknown function (DUF501) gnl|extdb|FAM14217-p1-1.1_000973 754252.PFREUD_17290 3.1e-170 604.4 Propionibacteriales ppx GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2GJBN@201174,4DQ85@85009,COG0248@1,COG0248@2 NA|NA|NA FP Ppx/GppA phosphatase family gnl|extdb|FAM14217-p1-1.1_000975 754252.PFREUD_17270 2.1e-247 861.3 Propionibacteriales Bacteria 2GIUM@201174,4DPE6@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000976 754252.PFREUD_17260 8.7e-94 349.7 Actinobacteria Bacteria 2GNND@201174,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000977 754252.PFREUD_17250 3.3e-244 850.5 Propionibacteriales eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2IA5M@201174,4DWPR@85009,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis gnl|extdb|FAM14217-p1-1.1_000978 754252.PFREUD_17240 4.7e-258 896.7 Propionibacteriales ko:K03294 ko00000 2.A.3.2 Bacteria 2GJ75@201174,4DPTX@85009,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM14217-p1-1.1_000979 754252.PFREUD_17230 7.4e-138 496.5 Actinobacteria Bacteria 2ID6I@201174,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding gnl|extdb|FAM14217-p1-1.1_000980 754252.PFREUD_17220 5e-147 526.9 Propionibacteriales Bacteria 2GM5T@201174,4DQPT@85009,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain gnl|extdb|FAM14217-p1-1.1_000981 754252.PFREUD_17210 4.6e-130 470.7 Propionibacteriales Bacteria 2GNCK@201174,4DQBD@85009,COG4760@1,COG4760@2 NA|NA|NA S Bax inhibitor 1 like gnl|extdb|FAM14217-p1-1.1_000982 754252.PFREUD_17200 4.2e-132 477.2 Propionibacteriales 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2GPP2@201174,4DQE2@85009,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain gnl|extdb|FAM14217-p1-1.1_000983 754252.PFREUD_17190 2.3e-165 588.2 Bacteria Bacteria 299UX@1,2ZWWZ@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000984 754252.PFREUD_17180 6e-120 437.2 Propionibacteriales mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNW1@201174,4DQWP@85009,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family gnl|extdb|FAM14217-p1-1.1_000985 754252.PFREUD_17160 1.8e-71 275.0 Bacteria Bacteria COG3832@1,COG3832@2 NA|NA|NA J glyoxalase III activity gnl|extdb|FAM14217-p1-1.1_000987 754252.PFREUD_17140 1.6e-96 358.6 Propionibacteriales Bacteria 2II1I@201174,4DR3V@85009,COG2318@1,COG2318@2 NA|NA|NA S Protein of unknown function (DUF664) gnl|extdb|FAM14217-p1-1.1_000988 754252.PFREUD_17130 1.3e-113 415.6 Actinobacteria yigB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.102,3.1.3.104 ko:K07025,ko:K20862,ko:K20866 ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120 M00125 R00548,R00947,R07280 RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2IHVB@201174,COG1011@1,COG1011@2 NA|NA|NA S haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED gnl|extdb|FAM14217-p1-1.1_000989 754252.PFREUD_17120 1.4e-113 415.6 Propionibacteriales ko:K07005 ko00000 Bacteria 2GJ76@201174,4DVES@85009,COG3467@1,COG3467@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase gnl|extdb|FAM14217-p1-1.1_000992 754252.PFREUD_17090 7.1e-132 476.5 Propionibacteriales ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ9Z@201174,4DT7D@85009,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gnl|extdb|FAM14217-p1-1.1_000993 754252.PFREUD_17080 1.3e-223 782.3 Propionibacteriales GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K20469 ko00000,ko02000 2.A.86.1.7 Bacteria 2GK0H@201174,4DNK8@85009,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter gnl|extdb|FAM14217-p1-1.1_000994 754252.PFREUD_17070 3e-173 614.4 Propionibacteriales Bacteria 2B5R0@1,2IPMA@201174,31YKI@2,4DR93@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000995 754252.PFREUD_17060 3.8e-67 260.8 Actinobacteria ko:K15977 ko00000 Bacteria 2GUAH@201174,COG2259@1,COG2259@2 NA|NA|NA S DoxX gnl|extdb|FAM14217-p1-1.1_000996 754252.PFREUD_17050 5.6e-86 323.6 Propionibacteriales greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 2GNZV@201174,4DQI3@85009,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides gnl|extdb|FAM14217-p1-1.1_000997 754252.PFREUD_17040 4.4e-185 653.7 Propionibacteriales mca GO:0006790,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0044237,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 ko:K18455 ko00000,ko01000 Bacteria 2H2NY@201174,4DP8N@85009,COG2120@1,COG2120@2 NA|NA|NA S A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics gnl|extdb|FAM14217-p1-1.1_001000 754252.PFREUD_17020 2.9e-93 347.8 Bacteria ko:K06888 ko00000 Bacteria COG4405@1,COG4405@2 NA|NA|NA I Protein conserved in bacteria gnl|extdb|FAM14217-p1-1.1_001001 754252.PFREUD_17010 4.5e-154 550.4 Propionibacteriales uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0033850,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 ko:K00806,ko:K12503 ko00900,ko01110,map00900,map01110 R06447,R08528 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2GJCP@201174,4DPJB@85009,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids gnl|extdb|FAM14217-p1-1.1_001003 754252.PFREUD_16990 1.7e-35 154.8 Bacteria xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria COG1722@1,COG1722@2 NA|NA|NA L exodeoxyribonuclease VII activity gnl|extdb|FAM14217-p1-1.1_001004 754252.PFREUD_16980 2.1e-220 771.5 Propionibacteriales xseA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJAS@201174,4DNJ0@85009,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides gnl|extdb|FAM14217-p1-1.1_001005 754252.PFREUD_16970 2.4e-181 641.3 Propionibacteriales ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 2GIZ7@201174,4DP0N@85009,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis gnl|extdb|FAM14217-p1-1.1_001006 754252.PFREUD_16950 6.5e-230 803.1 Propionibacteriales rmuC ko:K09760 ko00000 Bacteria 2GP4U@201174,4DN8P@85009,COG1322@1,COG1322@2 NA|NA|NA S RmuC family gnl|extdb|FAM14217-p1-1.1_001007 754252.PFREUD_16940 1.2e-241 842.0 Propionibacteriales apeB GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 ko:K01267 ko00000,ko01000,ko01002,ko04131 Bacteria 2GKW4@201174,4DPTA@85009,COG1362@1,COG1362@2 NA|NA|NA E Aminopeptidase I zinc metalloprotease (M18) gnl|extdb|FAM14217-p1-1.1_001008 754252.PFREUD_16930 3.4e-197 694.1 Propionibacteriales ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 2GIXI@201174,4DP3C@85009,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner gnl|extdb|FAM14217-p1-1.1_001009 931627.MycrhDRAFT_4488 6.4e-76 291.2 Actinobacteria Bacteria 2EK7R@1,2IPS3@201174,33DY3@2 NA|NA|NA S Protein of unknown function (DUF4238) gnl|extdb|FAM14217-p1-1.1_001010 498211.CJA_3635 5.8e-72 278.9 Gammaproteobacteria Bacteria 1R33M@1224,1T62P@1236,COG1384@1,COG1384@2 NA|NA|NA J Domain of unknown function (DUF4209) gnl|extdb|FAM14217-p1-1.1_001011 1122138.AQUZ01000008_gene3765 4.1e-213 747.3 Propionibacteriales Bacteria 2GJK7@201174,4DTG9@85009,COG3464@1,COG3464@2 NA|NA|NA L Transposase gnl|extdb|FAM14217-p1-1.1_001018 754252.PFREUD_16760 4.3e-129 467.2 Propionibacteriales Bacteria 2GNBC@201174,4DQ7I@85009,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain gnl|extdb|FAM14217-p1-1.1_001020 378753.KRH_07440 1.7e-12 78.6 Micrococcaceae Bacteria 1WA91@1268,2HWH4@201174,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain gnl|extdb|FAM14217-p1-1.1_001021 754252.PFREUD_16680 7.5e-115 419.9 Bacteria glpP ko:K02443 ko00000,ko03000 Bacteria COG1954@1,COG1954@2 NA|NA|NA K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA gnl|extdb|FAM14217-p1-1.1_001022 754252.PFREUD_16670 5.5e-302 1042.7 Propionibacteriales 2.5.1.26 ko:K00803,ko:K11472 ko00565,ko00630,ko01100,ko01110,ko01120,ko01130,ko04146,map00565,map00630,map01100,map01110,map01120,map01130,map04146 R00475,R04311 RC00020,RC00042,RC02886 ko00000,ko00001,ko01000 Bacteria 2GIS6@201174,4DNGC@85009,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain gnl|extdb|FAM14217-p1-1.1_001023 1120958.AULD01000005_gene2202 5.2e-176 624.4 Microbacteriaceae glpD_2 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJKN@201174,4FKEP@85023,COG0578@1,COG0578@2 NA|NA|NA C C-terminal domain of alpha-glycerophosphate oxidase gnl|extdb|FAM14217-p1-1.1_001027 754252.PFREUD_16580 1.6e-114 418.7 Propionibacteriales thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iJN678.thiE,iNJ661.Rv0414c Bacteria 2GKCN@201174,4DVRE@85009,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) gnl|extdb|FAM14217-p1-1.1_001028 754252.PFREUD_16570 4.1e-134 484.6 Propionibacteriales thiO 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 R07463 RC01788 ko00000,ko00001,ko01000 Bacteria 2GJVR@201174,4DR72@85009,COG0665@1,COG0665@2 NA|NA|NA C FAD dependent oxidoreductase gnl|extdb|FAM14217-p1-1.1_001029 754252.PFREUD_16570 1e-60 239.2 Propionibacteriales thiO 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 R07463 RC01788 ko00000,ko00001,ko01000 Bacteria 2GJVR@201174,4DR72@85009,COG0665@1,COG0665@2 NA|NA|NA C FAD dependent oxidoreductase gnl|extdb|FAM14217-p1-1.1_001030 754252.PFREUD_16560 6.7e-34 149.4 Bacteria thiS ko:K03154,ko:K03636 ko04122,map04122 ko00000,ko00001 Bacteria COG2104@1,COG2104@2 NA|NA|NA H thiamine diphosphate biosynthetic process gnl|extdb|FAM14217-p1-1.1_001031 754252.PFREUD_16550 2.1e-138 498.4 Propionibacteriales thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 Bacteria 2GM62@201174,4DP6Q@85009,COG2022@1,COG2022@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S gnl|extdb|FAM14217-p1-1.1_001033 754252.PFREUD_16530 1.5e-181 642.1 Propionibacteriales yeiH Bacteria 2GS6E@201174,4DQTV@85009,COG2855@1,COG2855@2 NA|NA|NA S Conserved hypothetical protein 698 gnl|extdb|FAM14217-p1-1.1_001034 754252.PFREUD_16520 2.4e-167 594.7 Propionibacteriales Bacteria 2I8WJ@201174,4DT8E@85009,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family gnl|extdb|FAM14217-p1-1.1_001035 754252.PFREUD_16510 2.7e-37 160.6 Actinobacteria ybdD Bacteria 2GQWY@201174,COG2879@1,COG2879@2 NA|NA|NA S Selenoprotein, putative gnl|extdb|FAM14217-p1-1.1_001036 754252.PFREUD_16500 0.0 1502.3 Propionibacteriales cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K06200 ko00000 Bacteria 2GIYX@201174,4DN9Z@85009,COG1966@1,COG1966@2 NA|NA|NA T 5TM C-terminal transporter carbon starvation CstA gnl|extdb|FAM14217-p1-1.1_001037 754252.PFREUD_16490 9.9e-200 702.6 Actinobacteria glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 2GKHX@201174,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family gnl|extdb|FAM14217-p1-1.1_001038 754252.PFREUD_16480 4.7e-305 1053.1 Propionibacteriales Bacteria 2GIUM@201174,4DTQ6@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_001039 754252.PFREUD_16470 2.1e-176 624.8 Actinobacteria ubiG Bacteria 2IIAX@201174,COG3865@1,COG3865@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase gnl|extdb|FAM14217-p1-1.1_001041 754252.PFREUD_16450 1.4e-156 558.9 Propionibacteriales proX ko:K05845 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GJWY@201174,4DNRX@85009,COG1732@1,COG1732@2 NA|NA|NA M Substrate binding domain of ABC-type glycine betaine transport system gnl|extdb|FAM14217-p1-1.1_001042 754252.PFREUD_16440 6.4e-227 793.1 Propionibacteriales ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 2GP5W@201174,4DQR2@85009,COG2807@1,COG2807@2 NA|NA|NA P Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_001043 1713.JOFV01000003_gene1575 1.9e-17 94.7 Cellulomonadaceae Bacteria 2GQV1@201174,4F2ZW@85016,COG4877@1,COG4877@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001044 754252.PFREUD_16430 3.9e-168 597.4 Propionibacteriales f42a Bacteria 2GM0Z@201174,4DTH0@85009,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues gnl|extdb|FAM14217-p1-1.1_001045 754252.PFREUD_16420 3.7e-179 634.0 Actinobacteria cysK 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIXE@201174,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family gnl|extdb|FAM14217-p1-1.1_001046 754252.PFREUD_16410 9.6e-197 692.6 Bacteria Bacteria COG1597@1,COG1597@2 NA|NA|NA I lipid kinase activity gnl|extdb|FAM14217-p1-1.1_001047 1122994.AUFR01000032_gene510 1.9e-12 79.7 Actinobacteria Bacteria 2DXWE@1,2H8B6@201174,346YS@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001048 1122994.AUFR01000032_gene510 7.4e-16 90.5 Actinobacteria Bacteria 2DXWE@1,2H8B6@201174,346YS@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001050 754252.PFREUD_16380 1.7e-90 338.6 Propionibacteriales gpt 2.4.2.22 ko:K00769,ko:K07101 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 2GN86@201174,4DRPW@85009,COG2236@1,COG2236@2 NA|NA|NA F Phosphoribosyl transferase domain gnl|extdb|FAM14217-p1-1.1_001052 754252.PFREUD_16360 5.5e-95 353.6 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM14217-p1-1.1_001053 754252.PFREUD_16350 5.1e-243 846.7 Propionibacteriales pimH Bacteria 2I2EY@201174,4DNW0@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_001054 754252.PFREUD_16340 1.9e-226 791.6 Actinobacteria dcuB ko:K07791,ko:K07792 ko02020,map02020 ko00000,ko00001,ko02000 2.A.13.1 Bacteria 2GKYB@201174,COG2704@1,COG2704@2 NA|NA|NA S Anaerobic c4-dicarboxylate gnl|extdb|FAM14217-p1-1.1_001055 754252.PFREUD_16330 1.1e-278 965.3 Propionibacteriales aspA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2250,iECs_1301.ECs5120,iG2583_1286.G2583_4966,iSBO_1134.SBO_4317,iSDY_1059.SDY_4444,iSF_1195.SF4293,iSFxv_1172.SFxv_4682,iSSON_1240.SSON_4322,iS_1188.S4560,iUTI89_1310.UTI89_C4736,iYL1228.KPN_04529,iZ_1308.Z5744,ic_1306.c5222 Bacteria 2I2HG@201174,4DPWH@85009,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus gnl|extdb|FAM14217-p1-1.1_001056 754252.PFREUD_16320 3.3e-280 970.3 Propionibacteriales aspA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2250,iECs_1301.ECs5120,iG2583_1286.G2583_4966,iSBO_1134.SBO_4317,iSDY_1059.SDY_4444,iSF_1195.SF4293,iSFxv_1172.SFxv_4682,iSSON_1240.SSON_4322,iS_1188.S4560,iUTI89_1310.UTI89_C4736,iYL1228.KPN_04529,iZ_1308.Z5744,ic_1306.c5222 Bacteria 2I2HG@201174,4DPWH@85009,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus gnl|extdb|FAM14217-p1-1.1_001058 754252.PFREUD_16300 1.7e-276 958.0 Propionibacteriales fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKWY@201174,4DNS5@85009,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate gnl|extdb|FAM14217-p1-1.1_001059 754252.PFREUD_16290 2.6e-180 637.9 Propionibacteriales 1.1.1.26,1.1.1.399,1.1.1.95 ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020 R00717,R01388,R01513 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2HBNQ@201174,4DPGQ@85009,COG1052@1,COG1052@2 NA|NA|NA CH D-isomer specific 2-hydroxyacid dehydrogenase gnl|extdb|FAM14217-p1-1.1_001060 754252.PFREUD_16280 2.9e-50 204.1 Propionibacteriales fdxA ko:K05524 ko00000 Bacteria 2IKVN@201174,4DR37@85009,COG1146@1,COG1146@2 NA|NA|NA C PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein gnl|extdb|FAM14217-p1-1.1_001061 754252.PFREUD_16270 2.1e-207 728.0 Propionibacteriales dapC Bacteria 2GJMI@201174,4DNQA@85009,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II gnl|extdb|FAM14217-p1-1.1_001062 754252.PFREUD_16260 4.6e-157 560.5 Propionibacteriales rpoC Bacteria 2GKXN@201174,4DQPK@85009,COG0739@1,COG0739@2 NA|NA|NA M PFAM NLP P60 protein gnl|extdb|FAM14217-p1-1.1_001063 754252.PFREUD_16250 5.8e-177 626.7 Propionibacteriales dapD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1201c Bacteria 2GIZ9@201174,4DMZE@85009,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA gnl|extdb|FAM14217-p1-1.1_001064 754252.PFREUD_16240 1.6e-210 738.4 Propionibacteriales dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK09@201174,4DN9X@85009,COG0624@1,COG0624@2 NA|NA|NA E Succinyl-diaminopimelate desuccinylase gnl|extdb|FAM14217-p1-1.1_001066 754252.PFREUD_16220 2.3e-265 921.0 Actinobacteria clcB ko:K03281 ko00000 2.A.49 Bacteria 2GPPN@201174,COG0038@1,COG0038@2 NA|NA|NA P Chloride channel gnl|extdb|FAM14217-p1-1.1_001067 1122994.AUFR01000009_gene1715 3.4e-14 84.7 Actinobacteria Bacteria 2DR5U@1,2GX63@201174,33AAR@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001068 754252.PFREUD_16200 1.1e-22 111.7 Actinobacteria Bacteria 2E39N@1,2GQFF@201174,32Y97@2 NA|NA|NA S Protein of unknown function (DUF3117) gnl|extdb|FAM14217-p1-1.1_001069 754252.PFREUD_16190 1.6e-235 821.6 Propionibacteriales glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 2I2EE@201174,4DN2C@85009,COG0297@1,COG0297@2 NA|NA|NA G Glycosyl transferases group 1 gnl|extdb|FAM14217-p1-1.1_001070 754252.PFREUD_16180 4.8e-243 846.7 Propionibacteriales glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2768 Bacteria 2I2EF@201174,4DPN8@85009,COG0448@1,COG0448@2 NA|NA|NA G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans gnl|extdb|FAM14217-p1-1.1_001072 754252.PFREUD_16160 2.7e-152 544.7 Propionibacteriales dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ34@201174,4DNA0@85009,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) gnl|extdb|FAM14217-p1-1.1_001073 754252.PFREUD_16150 2.7e-55 221.5 Propionibacteriales tatB GO:0008150,GO:0040007 ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2IR0U@201174,4DRKC@85009,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation gnl|extdb|FAM14217-p1-1.1_001074 754252.PFREUD_16140 2.5e-214 751.1 Propionibacteriales mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03593 ko00000,ko03029,ko03036 Bacteria 2GJUZ@201174,4DNNW@85009,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP gnl|extdb|FAM14217-p1-1.1_001075 754252.PFREUD_16130 5.3e-77 293.9 Propionibacteriales Bacteria 2GJRV@201174,4DQT8@85009,COG4420@1,COG4420@2 NA|NA|NA S Protein of unknown function (DUF1003) gnl|extdb|FAM14217-p1-1.1_001077 754252.PFREUD_16110 9.4e-158 562.8 Propionibacteriales citE 3.1.2.30,4.1.3.25,4.1.3.34 ko:K01644,ko:K14451,ko:K18292 ko00630,ko00660,ko01100,ko01120,ko01200,ko02020,map00630,map00660,map01100,map01120,map01200,map02020 M00373 R00237,R00362,R10612 RC00004,RC00014,RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK5J@201174,4DPA5@85009,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family gnl|extdb|FAM14217-p1-1.1_001079 754252.PFREUD_16090 4e-286 989.9 Propionibacteriales pepP 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 2GM7D@201174,4DNH3@85009,COG0006@1,COG0006@2 NA|NA|NA E to the peptidase M24B family gnl|extdb|FAM14217-p1-1.1_001080 754252.PFREUD_16080 1.4e-130 472.2 Propionibacteriales ko:K07164 ko00000 Bacteria 2GP84@201174,4DV7K@85009,COG1579@1,COG1579@2 NA|NA|NA S C4-type zinc ribbon domain gnl|extdb|FAM14217-p1-1.1_001082 754252.PFREUD_16070 2.6e-99 368.2 Bacteria Bacteria COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family gnl|extdb|FAM14217-p1-1.1_001084 754252.PFREUD_16050 2.8e-171 607.8 Bacteria Bacteria 2DYIV@1,34A0Z@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001085 754252.PFREUD_16040 8.5e-125 453.0 Bacteria Bacteria 2DYIV@1,34A0Z@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001087 754252.PFREUD_16030 2.7e-260 904.0 Propionibacteriales glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GJ2I@201174,4DNNP@85009,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase gnl|extdb|FAM14217-p1-1.1_001088 754252.PFREUD_16020 4.2e-130 470.7 Bacteria Bacteria COG3255@1,COG3255@2 NA|NA|NA I Sterol carrier protein gnl|extdb|FAM14217-p1-1.1_001089 754252.PFREUD_16010 0.0 1916.4 Propionibacteriales glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 ko00000,ko01000 Bacteria 2GJ91@201174,4DPAV@85009,COG1391@1,COG1391@2 NA|NA|NA H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell gnl|extdb|FAM14217-p1-1.1_001090 754252.PFREUD_16000 2.5e-144 518.1 Actinobacteria Bacteria 2I2RJ@201174,COG1028@1,COG1028@2 NA|NA|NA IQ Dehydrogenase gnl|extdb|FAM14217-p1-1.1_001094 754252.PFREUD_15960 0.0 1148.7 Propionibacteriales yjjK ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 2GJ5M@201174,4DNB0@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM14217-p1-1.1_001095 754252.PFREUD_15950 5.3e-112 410.6 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2AUFS@1,2GIXC@201174,31K3Y@2,4DQHR@85009 NA|NA|NA S Domain of unknown function (DUF4191) gnl|extdb|FAM14217-p1-1.1_001096 754252.PFREUD_15940 4.8e-225 787.3 Propionibacteriales sucB 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GMUV@201174,4DNH6@85009,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex gnl|extdb|FAM14217-p1-1.1_001097 754252.PFREUD_15930 6.2e-218 763.1 Propionibacteriales gcvT GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ47@201174,4DN5V@85009,COG0404@1,COG0404@2 NA|NA|NA E Glycine cleavage system T protein gnl|extdb|FAM14217-p1-1.1_001098 1120954.ATXE01000001_gene2350 1.7e-07 61.6 Propionibacteriales Bacteria 2EFWK@1,2IQXQ@201174,339NW@2,4DSKV@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001099 767029.HMPREF9154_2090 9.7e-31 140.2 Propionibacteriales GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 Bacteria 2AN86@1,2HWWU@201174,31D67@2,4DRVQ@85009 NA|NA|NA S Protein of unknown function (DUF3043) gnl|extdb|FAM14217-p1-1.1_001100 754252.PFREUD_15890 1.1e-131 476.1 Propionibacteriales pspA ko:K03969 ko00000 Bacteria 2GP0K@201174,4DPJS@85009,COG1842@1,COG1842@2 NA|NA|NA KT PspA/IM30 family gnl|extdb|FAM14217-p1-1.1_001101 1122998.AUHZ01000004_gene1041 1.7e-15 88.6 Propionibacteriales Bacteria 2E7WR@1,2I8C0@201174,332BD@2,4DS76@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001102 754252.PFREUD_15870 7.3e-156 556.6 Bacteria glxK GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria COG1929@1,COG1929@2 NA|NA|NA G organic acid phosphorylation gnl|extdb|FAM14217-p1-1.1_001103 754252.PFREUD_15860 8.2e-60 236.1 Propionibacteriales erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 2IHR0@201174,4DR9B@85009,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family gnl|extdb|FAM14217-p1-1.1_001104 754252.PFREUD_15850 3.3e-272 943.7 Propionibacteriales guaC GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016020,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iEC042_1314.EC042_0103,iECIAI39_1322.ECIAI39_0105,iECUMN_1333.ECUMN_0102 Bacteria 2GNDC@201174,4DN4P@85009,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F IMP dehydrogenase GMP reductase gnl|extdb|FAM14217-p1-1.1_001105 754252.PFREUD_15840 2.7e-91 341.3 Propionibacteriales GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 2II71@201174,4DQR3@85009,COG0784@1,COG0784@2 NA|NA|NA T cheY-homologous receiver domain gnl|extdb|FAM14217-p1-1.1_001106 754252.PFREUD_15830 9.9e-194 682.6 Propionibacteriales trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM4G@201174,4DP4R@85009,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) gnl|extdb|FAM14217-p1-1.1_001108 754252.PFREUD_15810 6e-123 446.8 Bacteria pppA 3.4.23.43 ko:K02654 M00331 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria COG1989@1,COG1989@2 NA|NA|NA NOU aspartic-type endopeptidase activity gnl|extdb|FAM14217-p1-1.1_001110 754252.PFREUD_15790 2.7e-218 764.2 Bacteria XK27_03185 ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria COG1670@1,COG1670@2,COG4696@1,COG4696@2 NA|NA|NA J Protein conserved in bacteria gnl|extdb|FAM14217-p1-1.1_001111 754252.PFREUD_15780 2.8e-153 548.1 Propionibacteriales rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GXD5@201174,4DVXM@85009,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel gnl|extdb|FAM14217-p1-1.1_001112 754252.PFREUD_15770 8.8e-95 352.8 Propionibacteriales ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 2IFUE@201174,4DQA4@85009,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gnl|extdb|FAM14217-p1-1.1_001113 754252.PFREUD_15760 5e-41 173.3 Propionibacteriales QU41_18010 2.4.2.18 ko:K00766,ko:K03719 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000,ko03000,ko03036 Bacteria 2IQD4@201174,4DRN1@85009,COG1522@1,COG1522@2 NA|NA|NA K Lrp/AsnC ligand binding domain gnl|extdb|FAM14217-p1-1.1_001114 754252.PFREUD_15750 2.5e-178 631.3 Propionibacteriales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GP1Y@201174,4DWGE@85009,COG4942@1,COG4942@2 NA|NA|NA D Peptidase family M23 gnl|extdb|FAM14217-p1-1.1_001115 754252.PFREUD_15740 3.7e-159 567.4 Propionibacteriales plsC2 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJ6V@201174,4DP1S@85009,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase gnl|extdb|FAM14217-p1-1.1_001116 754252.PFREUD_15730 1.3e-117 429.1 Bacteria cmk 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria COG0204@1,COG0204@2 NA|NA|NA I Acyl-transferase gnl|extdb|FAM14217-p1-1.1_001118 754252.PFREUD_15710 8.8e-124 449.5 Propionibacteriales Bacteria 2GNHK@201174,4DQBG@85009,COG2220@1,COG2220@2 NA|NA|NA S Beta-lactamase superfamily domain gnl|extdb|FAM14217-p1-1.1_001119 754252.PFREUD_15700 6.5e-157 560.1 Propionibacteriales ydeD Bacteria 2I8X5@201174,4DPV8@85009,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM14217-p1-1.1_001120 754252.PFREUD_15690 0.0 1245.7 Propionibacteriales Bacteria 2GJ1J@201174,4DPC3@85009,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM14217-p1-1.1_001127 754252.PFREUD_15610 2.1e-64 251.5 Bacteria Bacteria 2E49S@1,32Z5G@2 NA|NA|NA S Protein of unknown function (DUF3040) gnl|extdb|FAM14217-p1-1.1_001128 754252.PFREUD_15590 6e-76 290.0 Propionibacteriales mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 2IHUB@201174,4DQJP@85009,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family gnl|extdb|FAM14217-p1-1.1_001130 754252.PFREUD_15570 3.6e-72 277.7 Bacteria ftsL ko:K05589,ko:K12065 ko00000,ko02044,ko03036 3.A.7.11.1 Bacteria COG2919@1,COG2919@2 NA|NA|NA D cell cycle gnl|extdb|FAM14217-p1-1.1_001133 754252.PFREUD_15540 1.8e-276 958.0 Propionibacteriales murF 4.99.1.1,4.99.1.9,6.3.2.10 ko:K01772,ko:K01929 ko00300,ko00550,ko00860,ko01100,ko01110,ko01502,map00300,map00550,map00860,map01100,map01110,map01502 M00121 R00310,R04573,R04617,R11329 RC00064,RC00141,RC01012 ko00000,ko00001,ko00002,ko01000,ko01011 Bacteria 2GK0Y@201174,4DNW8@85009,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein gnl|extdb|FAM14217-p1-1.1_001134 754252.PFREUD_15530 7.3e-200 703.0 Propionibacteriales mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 2GNEH@201174,4DNZ9@85009,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gnl|extdb|FAM14217-p1-1.1_001135 754252.PFREUD_15520 3e-276 957.2 Propionibacteriales murD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2155c Bacteria 2GJZA@201174,4DNTV@85009,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) gnl|extdb|FAM14217-p1-1.1_001136 754252.PFREUD_15510 2.7e-214 751.1 Actinobacteria ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 2GKXP@201174,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family gnl|extdb|FAM14217-p1-1.1_001138 754252.PFREUD_15490 4.6e-274 949.9 Propionibacteriales murC GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2I2E7@201174,4DNNN@85009,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family gnl|extdb|FAM14217-p1-1.1_001139 754252.PFREUD_15480 1.4e-125 455.7 Bacteria ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 ko:K01921,ko:K03589,ko:K06438 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria COG1589@1,COG1589@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly gnl|extdb|FAM14217-p1-1.1_001140 754252.PFREUD_15470 1.3e-208 732.3 Propionibacteriales ftsZ GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 2GJWC@201174,4DND0@85009,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity gnl|extdb|FAM14217-p1-1.1_001141 754252.PFREUD_15460 1.5e-146 525.4 Propionibacteriales yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 2GN1M@201174,4DR2J@85009,COG1496@1,COG1496@2 NA|NA|NA S Multi-copper polyphenol oxidoreductase laccase gnl|extdb|FAM14217-p1-1.1_001142 754252.PFREUD_15450 5.1e-90 337.0 Propionibacteriales sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 2GNVH@201174,4DR13@85009,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA gnl|extdb|FAM14217-p1-1.1_001144 754252.PFREUD_15430 6.4e-57 228.0 Bacteria wag31 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 Bacteria COG3599@1,COG3599@2 NA|NA|NA D regulation of cell shape gnl|extdb|FAM14217-p1-1.1_001145 754252.PFREUD_15420 1.1e-71 275.8 Propionibacteriales dksA ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 2GJBE@201174,4DR4Q@85009,COG1734@1,COG1734@2 NA|NA|NA T Prokaryotic dksA/traR C4-type zinc finger gnl|extdb|FAM14217-p1-1.1_001147 754252.PFREUD_15400 4.6e-171 607.1 Propionibacteriales rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 2GIY1@201174,4DN88@85009,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil gnl|extdb|FAM14217-p1-1.1_001148 754252.PFREUD_15390 4.8e-282 976.5 Propionibacteriales pyk GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 Bacteria 2GJY8@201174,4DPR2@85009,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family gnl|extdb|FAM14217-p1-1.1_001150 754252.PFREUD_15370 4.3e-104 384.0 Actinobacteria pdtaR GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 ko:K22010 M00839 ko00000,ko00002,ko02022 Bacteria 2GK7T@201174,COG3707@1,COG3707@2 NA|NA|NA T response regulator gnl|extdb|FAM14217-p1-1.1_001151 754252.PFREUD_15360 0.0 1749.2 Propionibacteriales polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJY2@201174,4DNJG@85009,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity gnl|extdb|FAM14217-p1-1.1_001152 754252.PFREUD_15350 1.4e-130 472.2 Actinobacteria Bacteria 2DXBZ@1,2I77B@201174,344BK@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001153 754252.PFREUD_15340 8.5e-276 955.7 Propionibacteriales gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4DNDH@85009,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM14217-p1-1.1_001154 754252.PFREUD_15330 1.1e-230 805.8 Propionibacteriales rpsA ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJAK@201174,4DPIM@85009,COG0539@1,COG0539@2 NA|NA|NA J ribosomal protein gnl|extdb|FAM14217-p1-1.1_001155 754252.PFREUD_15320 5.2e-147 526.9 Actinobacteria 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 2IT3V@201174,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily gnl|extdb|FAM14217-p1-1.1_001156 754252.PFREUD_15310 1.3e-117 429.1 Propionibacteriales coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN96@201174,4DQNK@85009,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A gnl|extdb|FAM14217-p1-1.1_001157 754252.PFREUD_15300 0.0 1360.1 Propionibacteriales uvrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJ03@201174,4DN5W@85009,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage gnl|extdb|FAM14217-p1-1.1_001158 754252.PFREUD_15290 4.6e-175 620.5 Propionibacteriales terC ko:K05794 ko00000 Bacteria 2GIWU@201174,4DNU5@85009,COG0861@1,COG0861@2 NA|NA|NA P Membrane protein TerC gnl|extdb|FAM14217-p1-1.1_001159 754252.PFREUD_15280 9.2e-112 409.5 Propionibacteriales Bacteria 2GKJA@201174,4DPUP@85009,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily gnl|extdb|FAM14217-p1-1.1_001160 754252.PFREUD_15270 5.7e-143 513.5 Propionibacteriales 5.2.1.4 ko:K16163 ko00350,ko01100,ko01120,map00350,map01100,map01120 R03868 RC00867 ko00000,ko00001,ko01000 Bacteria 2C7TJ@1,2GP9X@201174,31RF6@2,4DS45@85009 NA|NA|NA S Mycothiol maleylpyruvate isomerase N-terminal domain gnl|extdb|FAM14217-p1-1.1_001161 754252.PFREUD_15260 0.0 1976.4 Propionibacteriales uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJUV@201174,4DN4J@85009,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate gnl|extdb|FAM14217-p1-1.1_001162 754252.PFREUD_15250 1e-98 365.9 Bacteria 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins gnl|extdb|FAM14217-p1-1.1_001163 754252.PFREUD_15240 1.5e-206 725.3 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I9MY@201174,4DQIN@85009,COG1668@1,COG1668@2 NA|NA|NA CP ABC-2 family transporter protein gnl|extdb|FAM14217-p1-1.1_001164 754252.PFREUD_15230 8.4e-162 576.2 Propionibacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I2DK@201174,4DP66@85009,COG4152@1,COG4152@2 NA|NA|NA S ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_001165 754252.PFREUD_15220 4.7e-109 400.6 Propionibacteriales Bacteria 2GJ46@201174,4DTUQ@85009,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon gnl|extdb|FAM14217-p1-1.1_001166 754252.PFREUD_15210 7.5e-250 869.4 Propionibacteriales Bacteria 2GJEG@201174,4DRHK@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM14217-p1-1.1_001167 754252.PFREUD_15200 0.0 1314.3 Propionibacteriales uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GIS4@201174,4DN4X@85009,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gnl|extdb|FAM14217-p1-1.1_001169 754252.PFREUD_15180 1.2e-174 619.0 Propionibacteriales ybhK Bacteria 2GJBW@201174,4DNYU@85009,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions gnl|extdb|FAM14217-p1-1.1_001170 754252.PFREUD_15170 5.9e-172 610.1 Propionibacteriales whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 ko:K09762 ko00000 Bacteria 2GJZU@201174,4DNGS@85009,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation gnl|extdb|FAM14217-p1-1.1_001174 754252.PFREUD_15140 1.6e-93 349.4 Bacteria Bacteria COG0577@1,COG0577@2 NA|NA|NA V efflux transmembrane transporter activity gnl|extdb|FAM14217-p1-1.1_001176 754252.PFREUD_15120 3.1e-223 780.8 Propionibacteriales pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJC6@201174,4DNJD@85009,COG0126@1,COG0126@2 NA|NA|NA G Belongs to the phosphoglycerate kinase family gnl|extdb|FAM14217-p1-1.1_001177 754252.PFREUD_15110 4.6e-143 513.8 Propionibacteriales tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.1.3.39,5.3.1.1 ko:K00927,ko:K01803,ko:K20905 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXZ@201174,4DP7B@85009,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) gnl|extdb|FAM14217-p1-1.1_001179 754252.PFREUD_15090 1.2e-61 242.3 Actinobacteria rbpA Bacteria 2CNY9@1,2IKKZ@201174,31GEE@2 NA|NA|NA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters gnl|extdb|FAM14217-p1-1.1_001180 754252.PFREUD_15080 1.2e-137 495.7 Propionibacteriales pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 ko:K01057,ko:K02003 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008,M00258 R02035 RC00537 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 Bacteria 2GMQ2@201174,4DQAQ@85009,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase gnl|extdb|FAM14217-p1-1.1_001181 754252.PFREUD_15070 7.3e-161 573.2 Propionibacteriales opcA Bacteria 2GJ1H@201174,4DP29@85009,COG3429@1,COG3429@2 NA|NA|NA G Glucose-6-phosphate dehydrogenase subunit gnl|extdb|FAM14217-p1-1.1_001183 754252.PFREUD_15050 9.8e-269 932.2 Propionibacteriales pdxR ko:K00375 ko00000,ko03000 Bacteria 2GJ5P@201174,4DPW7@85009,COG1167@1,COG1167@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor gnl|extdb|FAM14217-p1-1.1_001184 754252.PFREUD_15040 4e-159 567.4 Propionibacteriales pdxS GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 ko:K06215 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 Bacteria 2GK1T@201174,4DNEB@85009,COG0214@1,COG0214@2 NA|NA|NA H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively gnl|extdb|FAM14217-p1-1.1_001185 754252.PFREUD_15030 5.6e-104 383.6 Actinobacteria pdxT GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 iHN637.CLJU_RS19495 Bacteria 2GNYG@201174,COG0311@1,COG0311@2 NA|NA|NA H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS gnl|extdb|FAM14217-p1-1.1_001186 525246.HMPREF0058_2332 9.9e-24 117.5 Actinobacteria Bacteria 2DJRM@1,2IIWH@201174,3072U@2,4D7YY@85005 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001187 754252.PFREUD_15010 3.3e-129 467.6 Actinobacteria skfE ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GRE8@201174,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter gnl|extdb|FAM14217-p1-1.1_001188 754252.PFREUD_15000 4.9e-63 246.9 Actinobacteria ko:K07979 ko00000,ko03000 Bacteria 2IKDF@201174,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor gnl|extdb|FAM14217-p1-1.1_001190 754252.PFREUD_14980 5.5e-283 979.5 Propionibacteriales sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 2GKCZ@201174,4DN7B@85009,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) gnl|extdb|FAM14217-p1-1.1_001191 754252.PFREUD_14970 5e-229 800.0 Actinobacteria sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 2GJNV@201174,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD gnl|extdb|FAM14217-p1-1.1_001192 754252.PFREUD_14960 3.3e-61 240.7 Bacteria hcaC ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 Bacteria COG2146@1,COG2146@2 NA|NA|NA P nitrite reductase [NAD(P)H] activity gnl|extdb|FAM14217-p1-1.1_001193 754252.PFREUD_14950 3.2e-138 497.7 Propionibacteriales sufC ko:K09013 ko00000,ko02000 Bacteria 2GKB7@201174,4DNC0@85009,COG0396@1,COG0396@2 NA|NA|NA O assembly ATPase gnl|extdb|FAM14217-p1-1.1_001194 754252.PFREUD_14940 7.6e-241 839.3 Propionibacteriales sufS 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 2GIVK@201174,4DNCW@85009,COG0520@1,COG0520@2 NA|NA|NA E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family gnl|extdb|FAM14217-p1-1.1_001195 754252.PFREUD_14930 7e-80 303.1 Propionibacteriales iscU ko:K04488 ko00000 Bacteria 2IHY9@201174,4DQS7@85009,COG0822@1,COG0822@2 NA|NA|NA C NifU-like N terminal domain gnl|extdb|FAM14217-p1-1.1_001196 754252.PFREUD_14920 5.9e-79 300.1 Propionibacteriales yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 2IKUH@201174,4DR2I@85009,COG2151@1,COG2151@2 NA|NA|NA S Pfam:DUF59 gnl|extdb|FAM14217-p1-1.1_001198 754252.PFREUD_14890 2.5e-141 508.1 Actinobacteria rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 R07233 RC00003 ko00000,ko01000,ko03009 Bacteria 2HCAN@201174,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase gnl|extdb|FAM14217-p1-1.1_001199 754252.PFREUD_14880 2.8e-126 458.0 Propionibacteriales Bacteria 2GMEH@201174,4DNZG@85009,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM14217-p1-1.1_001201 754252.PFREUD_14860 4.7e-140 503.8 Propionibacteriales inhA GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208,ko:K11611 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJ65@201174,4DNM7@85009,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH gnl|extdb|FAM14217-p1-1.1_001202 1121933.AUHH01000032_gene1975 5.5e-37 161.4 Propionibacteriales Bacteria 2BK9Y@1,2GMZH@201174,32EQ4@2,4DR19@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001205 1121017.AUFG01000001_gene3122 1e-114 419.9 Intrasporangiaceae spoU2 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ12@201174,4FF53@85021,COG0566@1,COG0566@2 NA|NA|NA J RRNA methyltransferase gnl|extdb|FAM14217-p1-1.1_001206 321955.AAGP01000001_gene3245 1.1e-292 1011.9 Brevibacteriaceae hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GKAQ@201174,4FANT@85019,COG0286@1,COG0286@2 NA|NA|NA V HsdM N-terminal domain gnl|extdb|FAM14217-p1-1.1_001207 321955.AAGP01000001_gene3244 2.2e-168 598.2 Actinobacteria mrr ko:K07448 ko00000,ko02048 Bacteria 2GP9K@201174,COG1715@1,COG1715@2 NA|NA|NA L Restriction endonuclease gnl|extdb|FAM14217-p1-1.1_001208 1123013.AUIC01000004_gene1927 1e-85 323.9 Microbacteriaceae 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 2IAIR@201174,4FSB8@85023,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain gnl|extdb|FAM14217-p1-1.1_001209 321955.AAGP01000001_gene3242 0.0 1931.0 Actinobacteria hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2HI69@201174,COG0610@1,COG0610@2 NA|NA|NA L Subunit R is required for both nuclease and ATPase activities, but not for modification gnl|extdb|FAM14217-p1-1.1_001210 1121017.AUFG01000001_gene3125 3.7e-48 197.2 Actinobacteria Bacteria 2C2QN@1,2IK7E@201174,2ZKFV@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001212 754252.PFREUD_14810 1.2e-117 429.1 Propionibacteriales def 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2GJ87@201174,4DQAV@85009,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions gnl|extdb|FAM14217-p1-1.1_001213 754252.PFREUD_14800 4.4e-169 600.5 Propionibacteriales xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4DN7T@85009,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family. XerC subfamily gnl|extdb|FAM14217-p1-1.1_001214 754252.PFREUD_14790 4.4e-206 723.8 Actinobacteria Bacteria 2IQ64@201174,COG0739@1,COG0739@2 NA|NA|NA M peptidase gnl|extdb|FAM14217-p1-1.1_001215 754252.PFREUD_14780 5.4e-144 517.3 Propionibacteriales rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMYC@201174,4DP30@85009,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family gnl|extdb|FAM14217-p1-1.1_001216 754252.PFREUD_14770 6.2e-135 486.9 Propionibacteriales tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02357 ko00000,ko03012,ko03029 Bacteria 2GK4M@201174,4DNDW@85009,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome gnl|extdb|FAM14217-p1-1.1_001217 754252.PFREUD_14760 3.6e-131 474.2 Propionibacteriales pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2GKWQ@201174,4DNEC@85009,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP gnl|extdb|FAM14217-p1-1.1_001218 754252.PFREUD_14750 1.2e-93 349.4 Propionibacteriales frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2GJ9J@201174,4DNKY@85009,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another gnl|extdb|FAM14217-p1-1.1_001219 754252.PFREUD_14740 1.6e-154 552.0 Propionibacteriales cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNWK@201174,4DQ6M@85009,COG4589@1,COG4589@2 NA|NA|NA S Belongs to the CDS family gnl|extdb|FAM14217-p1-1.1_001221 754252.PFREUD_14720 4.8e-221 773.5 Propionibacteriales dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 2GIRV@201174,4DND1@85009,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) gnl|extdb|FAM14217-p1-1.1_001223 754252.PFREUD_14700 3.2e-158 564.3 Propionibacteriales ko:K06976 ko00000 Bacteria 2GMD2@201174,4DP1G@85009,COG3393@1,COG3393@2 NA|NA|NA S Domain of unknown function (DUF4081) gnl|extdb|FAM14217-p1-1.1_001224 754252.PFREUD_14690 0.0 1165.6 Propionibacteriales proS GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9G@201174,4DN8W@85009,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS gnl|extdb|FAM14217-p1-1.1_001226 754252.PFREUD_14670 2.3e-81 308.1 Propionibacteriales rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 2I9BT@201174,4DRA1@85009,COG0779@1,COG0779@2 NA|NA|NA S Required for maturation of 30S ribosomal subunits gnl|extdb|FAM14217-p1-1.1_001227 754252.PFREUD_14660 8.2e-196 689.5 Propionibacteriales nusA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 2GJDJ@201174,4DN47@85009,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination gnl|extdb|FAM14217-p1-1.1_001229 754252.PFREUD_14640 0.0 1312.0 Propionibacteriales infB GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02519 ko00000,ko03012,ko03029 Bacteria 2GKPH@201174,4DN57@85009,COG0481@1,COG0481@2,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gnl|extdb|FAM14217-p1-1.1_001230 754252.PFREUD_14630 7.6e-71 273.1 Propionibacteriales rbfA ko:K02834 ko00000,ko03009 Bacteria 2IKXP@201174,4DR3E@85009,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA gnl|extdb|FAM14217-p1-1.1_001231 754252.PFREUD_14620 1.9e-161 575.1 Propionibacteriales truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 2GJZK@201174,4DPKY@85009,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs gnl|extdb|FAM14217-p1-1.1_001232 754252.PFREUD_14610 3.3e-149 534.3 Propionibacteriales glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 2GKK3@201174,4DPG7@85009,COG0580@1,COG0580@2 NA|NA|NA G Belongs to the MIP aquaporin (TC 1.A.8) family gnl|extdb|FAM14217-p1-1.1_001233 754252.PFREUD_14600 5.9e-280 969.5 Propionibacteriales glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM13@201174,4DNYQ@85009,COG0554@1,COG0554@2 NA|NA|NA C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate gnl|extdb|FAM14217-p1-1.1_001234 754252.PFREUD_14590 7.8e-185 652.9 Propionibacteriales ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQF@201174,4DNXK@85009,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family gnl|extdb|FAM14217-p1-1.1_001235 754252.PFREUD_14580 4.4e-42 176.8 Propionibacteriales rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQA0@201174,4DS16@85009,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome gnl|extdb|FAM14217-p1-1.1_001236 754252.PFREUD_14570 0.0 1420.6 Propionibacteriales pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2GIT2@201174,4DP91@85009,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction gnl|extdb|FAM14217-p1-1.1_001237 754252.PFREUD_14560 8.1e-134 483.0 Propionibacteriales dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iYO844.BSU22490 Bacteria 2GM2T@201174,4DNG2@85009,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate gnl|extdb|FAM14217-p1-1.1_001238 1032480.MLP_15900 2.5e-10 72.8 Actinobacteria Bacteria 2AQTN@1,2IACN@201174,31G1R@2 NA|NA|NA S Protein of unknown function (DUF2993) gnl|extdb|FAM14217-p1-1.1_001239 754252.PFREUD_14540 5.3e-95 353.6 Propionibacteriales Bacteria 2I2XB@201174,4DQWV@85009,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family gnl|extdb|FAM14217-p1-1.1_001240 754252.PFREUD_14530 0.0 1109.4 Propionibacteriales rnj GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GIW7@201174,4DMZI@85009,COG0595@1,COG0595@2 NA|NA|NA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay gnl|extdb|FAM14217-p1-1.1_001241 754252.PFREUD_14520 1e-29 135.2 Actinobacteria rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQNU@201174,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family gnl|extdb|FAM14217-p1-1.1_001243 754252.PFREUD_14500 2e-76 291.6 Propionibacteriales ko:K07005 ko00000 Bacteria 2IQ9Y@201174,4DVJV@85009,COG3467@1,COG3467@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase gnl|extdb|FAM14217-p1-1.1_001244 754252.PFREUD_14490 4e-107 394.0 Propionibacteriales rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2GQ3G@201174,4DQZ1@85009,COG0742@1,COG0742@2 NA|NA|NA L Conserved hypothetical protein 95 gnl|extdb|FAM14217-p1-1.1_001245 754252.PFREUD_14480 3.5e-85 320.9 Propionibacteriales coaD GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN1S@201174,4DR12@85009,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate gnl|extdb|FAM14217-p1-1.1_001246 754252.PFREUD_14470 3.9e-104 384.0 Propionibacteriales yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 2GJTS@201174,4DQUU@85009,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 gnl|extdb|FAM14217-p1-1.1_001247 1111131.HMPREF1255_0135 2.9e-20 104.0 Propionibacteriales rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2GQP3@201174,4DS4H@85009,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family gnl|extdb|FAM14217-p1-1.1_001248 754252.PFREUD_14460 5.1e-133 480.3 Propionibacteriales rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2GKER@201174,4DN7J@85009,COG0571@1,COG0571@2 NA|NA|NA K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism gnl|extdb|FAM14217-p1-1.1_001249 754252.PFREUD_14440 3.9e-170 604.0 Propionibacteriales fpg GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJNT@201174,4DN5R@85009,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates gnl|extdb|FAM14217-p1-1.1_001251 754252.PFREUD_14420 0.0 1577.8 Propionibacteriales smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 2GK93@201174,4DN2T@85009,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning gnl|extdb|FAM14217-p1-1.1_001253 754252.PFREUD_14400 2.1e-181 641.7 Propionibacteriales ftsY GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 2GJQH@201174,4DN3Z@85009,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) gnl|extdb|FAM14217-p1-1.1_001254 754252.PFREUD_14390 2.2e-269 934.5 Propionibacteriales ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2GK4R@201174,4DNUI@85009,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY gnl|extdb|FAM14217-p1-1.1_001255 754252.PFREUD_14380 1.3e-212 745.3 Propionibacteriales 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKRZ@201174,4DP0W@85009,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family gnl|extdb|FAM14217-p1-1.1_001256 754252.PFREUD_14370 4.7e-69 267.3 Propionibacteriales rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IKU0@201174,4DQZU@85009,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family gnl|extdb|FAM14217-p1-1.1_001257 754252.PFREUD_14360 8.9e-40 169.1 Propionibacteriales CP_0960 GO:0008150,GO:0040007 ko:K06960 ko00000 Bacteria 2IQ4C@201174,4DSI2@85009,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family gnl|extdb|FAM14217-p1-1.1_001258 754252.PFREUD_14350 4.2e-95 354.0 Propionibacteriales rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 2GK4I@201174,4DRAZ@85009,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes gnl|extdb|FAM14217-p1-1.1_001260 754252.PFREUD_14330 1.3e-133 482.3 Bacteria Bacteria COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity gnl|extdb|FAM14217-p1-1.1_001261 754252.PFREUD_14320 1.3e-131 475.7 Propionibacteriales sdhC ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 28HIR@1,2GN2S@201174,2Z7U4@2,4DQJ4@85009 NA|NA|NA S succinate dehydrogenase gnl|extdb|FAM14217-p1-1.1_001262 754252.PFREUD_14310 0.0 1381.3 Propionibacteriales sdhA 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ45@201174,4DN0E@85009,COG1053@1,COG1053@2 NA|NA|NA C succinate dehydrogenase gnl|extdb|FAM14217-p1-1.1_001263 754252.PFREUD_14300 1e-147 529.3 Propionibacteriales sdhB 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJPS@201174,4DPU6@85009,COG0479@1,COG0479@2 NA|NA|NA C Succinate dehydrogenase fumarate reductase gnl|extdb|FAM14217-p1-1.1_001264 754252.PFREUD_14290 1.6e-58 231.9 Propionibacteriales rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRT@201174,4DQSW@85009,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site gnl|extdb|FAM14217-p1-1.1_001265 754252.PFREUD_14280 1.9e-138 498.4 Propionibacteriales lepB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GIYN@201174,4DQK9@85009,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family gnl|extdb|FAM14217-p1-1.1_001267 754252.PFREUD_14260 5.1e-53 213.4 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2AFXT@1,2IKPZ@201174,3161G@2,4DR0E@85009 NA|NA|NA S Protein of unknown function (DUF2469) gnl|extdb|FAM14217-p1-1.1_001268 754252.PFREUD_14250 1.2e-64 252.3 Actinobacteria yraN ko:K07460 ko00000 Bacteria 2IQ3X@201174,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family gnl|extdb|FAM14217-p1-1.1_001269 754252.PFREUD_14240 1.4e-284 984.9 Propionibacteriales comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K06400,ko:K07391 ko00000 Bacteria 2GJIQ@201174,4DNC3@85009,COG0606@1,COG0606@2 NA|NA|NA O Magnesium chelatase, subunit ChlI C-terminal gnl|extdb|FAM14217-p1-1.1_001270 754252.PFREUD_14230 2.7e-216 757.7 Actinobacteria dprA 5.99.1.2 ko:K03168,ko:K04096 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKDA@201174,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA gnl|extdb|FAM14217-p1-1.1_001271 754252.PFREUD_14220 3.9e-262 910.2 Propionibacteriales trpB 4.2.1.20 ko:K01696,ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GP7D@201174,4DPK3@85009,COG1350@1,COG1350@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine gnl|extdb|FAM14217-p1-1.1_001272 754252.PFREUD_14210 3.8e-66 257.3 Propionibacteriales Bacteria 2GSU0@201174,4DVMP@85009,COG1433@1,COG1433@2 NA|NA|NA S Dinitrogenase iron-molybdenum cofactor gnl|extdb|FAM14217-p1-1.1_001273 754252.PFREUD_14200 8.9e-145 519.6 Propionibacteriales uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJVG@201174,4DQ00@85009,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin gnl|extdb|FAM14217-p1-1.1_001280 754252.PFREUD_14130 1.2e-246 858.6 Propionibacteriales cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iNJ661.Rv2130c Bacteria 2GJZR@201174,4DNNY@85009,COG0215@1,COG0215@2 NA|NA|NA J Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins gnl|extdb|FAM14217-p1-1.1_001281 754252.PFREUD_14120 0.0 1334.7 Propionibacteriales ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2H5KC@201174,4DWPQ@85009,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins gnl|extdb|FAM14217-p1-1.1_001282 754252.PFREUD_14110 2.9e-41 174.1 Actinobacteria hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860 Bacteria 2IQ4D@201174,COG0140@1,COG0140@2 NA|NA|NA E Phosphoribosyl-ATP gnl|extdb|FAM14217-p1-1.1_001283 754252.PFREUD_14100 2.8e-154 551.2 Propionibacteriales hisG GO:0000105,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003879,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0052803,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNAX@201174,4DTZ7@85009,COG0040@1,COG0040@2 NA|NA|NA E ATP phosphoribosyltransferase gnl|extdb|FAM14217-p1-1.1_001284 1003195.SCAT_5284 7.7e-08 63.9 Actinobacteria Bacteria 2F46V@1,2II56@201174,33WXW@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001285 754252.PFREUD_14070 6.5e-104 383.6 Propionibacteriales infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2GJGT@201174,4DNG8@85009,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins gnl|extdb|FAM14217-p1-1.1_001286 754252.PFREUD_14060 1.7e-27 127.9 Propionibacteriales rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQZW@201174,4DSHV@85009,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family gnl|extdb|FAM14217-p1-1.1_001287 754252.PFREUD_14050 1.3e-58 232.3 Propionibacteriales rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHTN@201174,4DQY2@85009,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit gnl|extdb|FAM14217-p1-1.1_001288 754252.PFREUD_14040 3.2e-158 564.3 Actinobacteria tsnR 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJI6@201174,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gnl|extdb|FAM14217-p1-1.1_001290 754252.PFREUD_14020 3.9e-209 733.8 Propionibacteriales pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJGG@201174,4DPA8@85009,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily gnl|extdb|FAM14217-p1-1.1_001291 754252.PFREUD_14010 0.0 1675.2 Propionibacteriales pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GMFD@201174,4DPEJ@85009,COG0072@1,COG0072@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily gnl|extdb|FAM14217-p1-1.1_001292 754252.PFREUD_14000 2.8e-240 837.4 Propionibacteriales aat3 2.6.1.2,2.6.1.66 ko:K00814,ko:K14260 ko00220,ko00250,ko00290,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00290,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00171 R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ7R@201174,4DN56@85009,COG0436@1,COG0436@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family gnl|extdb|FAM14217-p1-1.1_001293 754252.PFREUD_13990 4.4e-194 683.7 Propionibacteriales argC GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQK@201174,4DNZ7@85009,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde gnl|extdb|FAM14217-p1-1.1_001294 754252.PFREUD_13980 6.6e-215 753.1 Propionibacteriales argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIW0@201174,4DN1T@85009,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate gnl|extdb|FAM14217-p1-1.1_001295 754252.PFREUD_13970 2e-167 595.1 Propionibacteriales argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784 Bacteria 2GKDS@201174,4DPCE@85009,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily gnl|extdb|FAM14217-p1-1.1_001296 754252.PFREUD_13960 4.1e-234 817.0 Propionibacteriales argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKE9@201174,4DNMX@85009,COG4992@1,COG4992@2 NA|NA|NA E Aminotransferase class-III gnl|extdb|FAM14217-p1-1.1_001297 754252.PFREUD_13950 1.4e-82 312.4 Propionibacteriales argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 2GKA5@201174,4DQUP@85009,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes gnl|extdb|FAM14217-p1-1.1_001298 754252.PFREUD_13940 2.7e-258 897.5 Propionibacteriales argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argH Bacteria 2GJ2A@201174,4DPEP@85009,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase gnl|extdb|FAM14217-p1-1.1_001299 754252.PFREUD_13930 3.6e-238 830.5 Propionibacteriales tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJPR@201174,4DNWH@85009,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) gnl|extdb|FAM14217-p1-1.1_001306 754252.PFREUD_13730 2.5e-197 694.5 Propionibacteriales yutF GO:0000121,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030145,GO:0042578,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0071704,GO:1901575 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 R03024 RC00151 ko00000,ko00001,ko01000 Bacteria 2GK7V@201174,4DPB1@85009,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase gnl|extdb|FAM14217-p1-1.1_001307 754252.PFREUD_13720 7.8e-77 293.5 Propionibacteriales bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 2GJ53@201174,4DRM2@85009,COG1268@1,COG1268@2 NA|NA|NA S BioY family gnl|extdb|FAM14217-p1-1.1_001308 754252.PFREUD_13710 6.6e-120 436.8 Propionibacteriales ko:K16784,ko:K16786 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4DQ9U@85009,COG1122@1,COG1122@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_001309 754252.PFREUD_13690 7.7e-98 363.2 Actinobacteria bioN ko:K16783 ko02010,map02010 M00581 ko00000,ko00001,ko00002,ko02000 3.A.1.25.1 Bacteria 2IQMQ@201174,COG0619@1,COG0619@2 NA|NA|NA P ABC-type cobalt transport system permease component CbiQ gnl|extdb|FAM14217-p1-1.1_001311 754252.PFREUD_13670 2.5e-173 614.8 Propionibacteriales nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2GKM2@201174,4DPDG@85009,COG0061@1,COG0061@2 NA|NA|NA G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP gnl|extdb|FAM14217-p1-1.1_001313 754252.PFREUD_13650 0.0 1163.3 Propionibacteriales pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 2GJ13@201174,4DP71@85009,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates gnl|extdb|FAM14217-p1-1.1_001315 754252.PFREUD_13630 9.3e-184 649.4 Propionibacteriales xerD GO:0008150,GO:0040007 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4DNSC@85009,COG4974@1,COG4974@2 NA|NA|NA L tyrosine recombinase gnl|extdb|FAM14217-p1-1.1_001316 754252.PFREUD_13620 1.5e-161 575.5 Propionibacteriales soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GJX3@201174,4DP0V@85009,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ gnl|extdb|FAM14217-p1-1.1_001318 754252.PFREUD_13600 7.9e-163 579.7 Propionibacteriales scpA ko:K05896 ko00000,ko03036 Bacteria 2GN1U@201174,4DMYR@85009,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves gnl|extdb|FAM14217-p1-1.1_001320 754252.PFREUD_13580 1.3e-142 512.3 Propionibacteriales rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2GJ4N@201174,4DNT7@85009,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family gnl|extdb|FAM14217-p1-1.1_001322 754252.PFREUD_13560 1.8e-155 555.4 Propionibacteriales fkbB 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2GJK2@201174,4DRPD@85009,COG0545@1,COG0545@2 NA|NA|NA O FKBP-type peptidyl-prolyl cis-trans isomerase gnl|extdb|FAM14217-p1-1.1_001323 754252.PFREUD_13550 1.4e-181 642.1 Actinobacteria gluQ 6.1.1.17 ko:K01885,ko:K01894 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 2GKMT@201174,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gnl|extdb|FAM14217-p1-1.1_001324 754252.PFREUD_13540 3.9e-176 624.0 Propionibacteriales pafB ko:K13572 ko00000,ko03051 Bacteria 2GM46@201174,4DNBD@85009,COG2378@1,COG2378@2 NA|NA|NA K WYL domain gnl|extdb|FAM14217-p1-1.1_001325 754252.PFREUD_13530 1.6e-174 618.6 Propionibacteriales pafC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K13573 ko00000,ko03051 Bacteria 2GMAU@201174,4DP7N@85009,COG2378@1,COG2378@2 NA|NA|NA K WYL domain gnl|extdb|FAM14217-p1-1.1_001326 1120954.ATXE01000002_gene693 1.4e-10 72.4 Propionibacteriales tatA ko:K03116 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2HZG4@201174,4DSNW@85009,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system gnl|extdb|FAM14217-p1-1.1_001328 754252.PFREUD_13490 2.8e-165 587.8 Propionibacteriales dagK GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GK3P@201174,4DPPK@85009,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain gnl|extdb|FAM14217-p1-1.1_001331 754252.PFREUD_13470 6.1e-157 560.1 Bacteria Bacteria COG0561@1,COG0561@2 NA|NA|NA Q phosphatase activity gnl|extdb|FAM14217-p1-1.1_001333 754252.PFREUD_13450 1.7e-59 235.0 Actinobacteria Bacteria 2IQ6Y@201174,COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase gnl|extdb|FAM14217-p1-1.1_001334 754252.PFREUD_13440 1.4e-192 678.7 Propionibacteriales GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008 Bacteria 2GMT5@201174,4DN73@85009,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM14217-p1-1.1_001335 754252.PFREUD_13430 6e-140 503.4 Propionibacteriales hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRP@201174,4DPEF@85009,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit gnl|extdb|FAM14217-p1-1.1_001337 754252.PFREUD_13410 0.0 1176.4 Propionibacteriales ilvB 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKU4@201174,4DNJX@85009,COG0028@1,COG0028@2 NA|NA|NA E Thiamine pyrophosphate enzyme, central domain gnl|extdb|FAM14217-p1-1.1_001338 754252.PFREUD_13400 5.5e-84 317.0 Propionibacteriales ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ilvN,iJN678.ilvN Bacteria 2GJCH@201174,4DQCD@85009,COG0440@1,COG0440@2 NA|NA|NA E Acetolactate synthase gnl|extdb|FAM14217-p1-1.1_001339 754252.PFREUD_13390 8.8e-195 686.0 Propionibacteriales ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXA@201174,4DNFA@85009,COG0059@1,COG0059@2 NA|NA|NA EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate gnl|extdb|FAM14217-p1-1.1_001340 428125.CLOLEP_00158 5.6e-09 68.6 Clostridia Bacteria 1W1G1@1239,252S6@186801,29XDV@1,30J3Z@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001342 754252.PFREUD_13360 5.9e-194 683.3 Propionibacteriales leuB 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GK44@201174,4DPJF@85009,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate gnl|extdb|FAM14217-p1-1.1_001343 754252.PFREUD_13350 2e-213 748.0 Propionibacteriales ilvE GO:0000082,GO:0000278,GO:0003674,GO:0003824,GO:0004084,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006573,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008283,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009082,GO:0009083,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0022402,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903047 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKJ1@201174,4DPRZ@85009,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase gnl|extdb|FAM14217-p1-1.1_001344 754252.PFREUD_13340 5.7e-310 1069.3 Propionibacteriales cimA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GKYT@201174,4DNDJ@85009,COG0119@1,COG0119@2 NA|NA|NA E Belongs to the alpha-IPM synthase homocitrate synthase family gnl|extdb|FAM14217-p1-1.1_001345 754252.PFREUD_13330 2.4e-158 564.7 Propionibacteriales fahA Bacteria 2GN2G@201174,4DPHV@85009,COG0179@1,COG0179@2 NA|NA|NA Q Domain of unknown function (DUF2437) gnl|extdb|FAM14217-p1-1.1_001346 754252.PFREUD_13320 1.5e-184 652.1 Propionibacteriales ko:K07052 ko00000 Bacteria 2GR9Y@201174,4DWVR@85009,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM14217-p1-1.1_001349 754252.PFREUD_13290 6.8e-125 453.4 Propionibacteriales ltbR Bacteria 2GKB0@201174,4DP77@85009,COG1414@1,COG1414@2 NA|NA|NA K helix_turn_helix isocitrate lyase regulation gnl|extdb|FAM14217-p1-1.1_001350 754252.PFREUD_13280 1.8e-270 937.9 Propionibacteriales leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0030312,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531 Bacteria 2GKT7@201174,4DNZM@85009,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate gnl|extdb|FAM14217-p1-1.1_001351 754252.PFREUD_13270 9.2e-112 409.5 Propionibacteriales leuD GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2987c Bacteria 2GJ8Z@201174,4DPSM@85009,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate gnl|extdb|FAM14217-p1-1.1_001352 754252.PFREUD_13260 7.1e-152 543.1 Propionibacteriales plsC1 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GKVA@201174,4DQUS@85009,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases gnl|extdb|FAM14217-p1-1.1_001353 754252.PFREUD_13250 7.6e-216 756.1 Actinobacteria ddl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008716,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464,GO:0050896 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Bacteria 2GITC@201174,COG1181@1,COG1181@2 NA|NA|NA M Belongs to the D-alanine--D-alanine ligase family gnl|extdb|FAM14217-p1-1.1_001354 754252.PFREUD_13240 3.4e-188 664.1 Actinobacteria Bacteria 28H6R@1,2I9RC@201174,2Z7J3@2 NA|NA|NA S Psort location CytoplasmicMembrane, score gnl|extdb|FAM14217-p1-1.1_001355 754252.PFREUD_13230 1.4e-122 445.7 Actinobacteria dhaS Bacteria 2H5KV@201174,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM14217-p1-1.1_001356 754252.PFREUD_13220 1.8e-181 641.7 Propionibacteriales thiL GO:0008150,GO:0040007 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2977c,iYO844.BSU05900 Bacteria 2GP6E@201174,4DNV9@85009,COG0611@1,COG0611@2 NA|NA|NA H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 gnl|extdb|FAM14217-p1-1.1_001357 754252.PFREUD_13210 0.0 1481.1 Propionibacteriales ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2GK3T@201174,4DN14@85009,COG1674@1,COG1674@2 NA|NA|NA D Ftsk_gamma gnl|extdb|FAM14217-p1-1.1_001358 754252.PFREUD_13200 4.4e-269 933.3 Propionibacteriales rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 2GKRI@201174,4DNHY@85009,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 gnl|extdb|FAM14217-p1-1.1_001359 754252.PFREUD_13190 1.4e-116 425.6 Propionibacteriales pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GK5D@201174,4DQPW@85009,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family gnl|extdb|FAM14217-p1-1.1_001361 754252.PFREUD_13160 3.3e-41 174.5 Propionibacteriales clgR GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 2GR3F@201174,4DS8T@85009,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM14217-p1-1.1_001362 754252.PFREUD_13150 0.0 3067.3 Propionibacteriales lhr GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 ko:K03724 ko00000,ko01000,ko03400 Bacteria 2GJG3@201174,4DPDX@85009,COG1201@1,COG1201@2 NA|NA|NA L DEAD/H associated gnl|extdb|FAM14217-p1-1.1_001363 754252.PFREUD_13140 4e-32 143.3 Propionibacteriales Bacteria 2AU8K@1,2HZCZ@201174,31JVT@2,4DS5N@85009 NA|NA|NA S Protein of unknown function (DUF3046) gnl|extdb|FAM14217-p1-1.1_001364 754252.PFREUD_13130 1.7e-188 665.2 Propionibacteriales recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 2GJ4P@201174,4DPDK@85009,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage gnl|extdb|FAM14217-p1-1.1_001365 754252.PFREUD_13120 6.4e-92 343.6 Actinobacteria recX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03565 ko00000,ko03400 Bacteria 2GMRF@201174,COG2137@1,COG2137@2 NA|NA|NA S regulatory protein RecX gnl|extdb|FAM14217-p1-1.1_001366 754252.PFREUD_13110 2.2e-213 748.4 Propionibacteriales rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2I9DW@201174,4DQ4C@85009,COG1418@1,COG1418@2 NA|NA|NA M Endoribonuclease that initiates mRNA decay gnl|extdb|FAM14217-p1-1.1_001367 754252.PFREUD_13100 9.2e-147 526.2 Propionibacteriales gluA 3.6.3.21 ko:K02028,ko:K10008 ko02010,map02010 M00233,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GIZW@201174,4DNTI@85009,COG1126@1,COG1126@2 NA|NA|NA E ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_001368 754252.PFREUD_13090 9e-297 1025.4 Propionibacteriales miaB 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2GJEV@201174,4DNBY@85009,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine gnl|extdb|FAM14217-p1-1.1_001369 754252.PFREUD_13080 8.2e-182 642.9 Propionibacteriales miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2GKFT@201174,4DP56@85009,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) gnl|extdb|FAM14217-p1-1.1_001370 754252.PFREUD_13070 2.3e-161 574.7 Propionibacteriales dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 2GKUD@201174,4DN7Z@85009,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan gnl|extdb|FAM14217-p1-1.1_001371 754252.PFREUD_13060 4e-262 910.2 Propionibacteriales hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K03665 ko00000,ko03009 Bacteria 2GK55@201174,4DNPS@85009,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis gnl|extdb|FAM14217-p1-1.1_001373 754252.PFREUD_13040 8.3e-151 539.7 Propionibacteriales lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2GMBN@201174,4DNCQ@85009,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair gnl|extdb|FAM14217-p1-1.1_001375 754252.PFREUD_13020 8.5e-87 326.2 Propionibacteriales nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 2IHU9@201174,4DQJU@85009,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes gnl|extdb|FAM14217-p1-1.1_001376 754252.PFREUD_13010 0.0 1903.3 Propionibacteriales nrdJ 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2GKX9@201174,4DP4H@85009,COG0209@1,COG0209@2 NA|NA|NA F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen gnl|extdb|FAM14217-p1-1.1_001377 754252.PFREUD_13000 4.4e-177 627.1 Propionibacteriales Bacteria 2I8R7@201174,4DRYI@85009,COG4667@1,COG4667@2 NA|NA|NA S Patatin-like phospholipase gnl|extdb|FAM14217-p1-1.1_001379 754252.PFREUD_12980 5.1e-248 863.2 Actinobacteria glpB GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009061,GO:0009987,GO:0010181,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046168,GO:0046434,GO:0048037,GO:0050662,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575 1.1.5.3 ko:K00112 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 iB21_1397.B21_02127,iEC042_1314.EC042_2485,iECBD_1354.ECBD_1418,iECB_1328.ECB_02168,iECD_1391.ECD_02168,iECUMN_1333.ECUMN_2582,iEcHS_1320.EcHS_A2383,iUMNK88_1353.UMNK88_2792 Bacteria 2GMNS@201174,COG3075@1,COG3075@2 NA|NA|NA E Glycerol-3-phosphate dehydrogenase gnl|extdb|FAM14217-p1-1.1_001380 754252.PFREUD_12970 1.1e-261 908.7 Actinobacteria glpC GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 ko:K00113 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2H9RN@201174,COG0247@1,COG0247@2 NA|NA|NA C Glycerol-3-phosphate dehydrogenase gnl|extdb|FAM14217-p1-1.1_001381 754252.PFREUD_12960 2.8e-171 607.8 Actinobacteria Bacteria 2GMIM@201174,COG2390@1,COG2390@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_001382 754252.PFREUD_12940 1.2e-163 582.4 Propionibacteriales mdcF ko:K07088 ko00000 Bacteria 2GNIA@201174,4DPWX@85009,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein gnl|extdb|FAM14217-p1-1.1_001383 754252.PFREUD_12930 0.0 1773.8 Propionibacteriales xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 2GN27@201174,4DNF9@85009,COG3957@1,COG3957@2 NA|NA|NA G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase gnl|extdb|FAM14217-p1-1.1_001384 754252.PFREUD_12920 0.0 2600.1 Propionibacteriales hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 ko00000,ko01000 Bacteria 2GIWX@201174,4DNBR@85009,COG1643@1,COG1643@2 NA|NA|NA L ATP-dependent helicase hrpA gnl|extdb|FAM14217-p1-1.1_001385 754252.PFREUD_12910 1.6e-165 588.6 Propionibacteriales tesB ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 2GJ1B@201174,4DN4N@85009,COG1946@1,COG1946@2 NA|NA|NA I Acyl-CoA thioesterase gnl|extdb|FAM14217-p1-1.1_001388 754252.PFREUD_12860 3.8e-165 587.4 Propionibacteriales sigA ko:K03086 ko00000,ko03021 Bacteria 2GK3Z@201174,4DNNR@85009,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released gnl|extdb|FAM14217-p1-1.1_001389 754252.PFREUD_12850 2.1e-213 748.4 Propionibacteriales sigA ko:K03086 ko00000,ko03021 Bacteria 2GK3Z@201174,4DN2F@85009,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth gnl|extdb|FAM14217-p1-1.1_001390 754252.PFREUD_12840 8.6e-176 622.9 Propionibacteriales ldh 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GN5S@201174,4DV68@85009,COG0039@1,COG0039@2 NA|NA|NA C lactate/malate dehydrogenase, NAD binding domain gnl|extdb|FAM14217-p1-1.1_001391 754252.PFREUD_12830 7.1e-29 132.5 Actinobacteria Bacteria 2E39Y@1,2GQJA@201174,32Y9G@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001393 754252.PFREUD_12810 4.1e-167 594.0 Propionibacteriales panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 2I3AM@201174,4DUY3@85009,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid gnl|extdb|FAM14217-p1-1.1_001394 754252.PFREUD_12800 0.0 1604.3 Propionibacteriales gyrA GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJ2Q@201174,4DPNM@85009,COG0188@1,COG0188@2 NA|NA|NA L DNA Topoisomerase IV gnl|extdb|FAM14217-p1-1.1_001395 754252.PFREUD_12790 6.8e-214 749.6 Actinobacteria Bacteria 2GKPS@201174,COG4850@1,COG4850@2 NA|NA|NA S Uncharacterized conserved protein (DUF2183) gnl|extdb|FAM14217-p1-1.1_001397 754252.PFREUD_12770 4.8e-226 790.0 Propionibacteriales Bacteria 2GISU@201174,4DNS7@85009,COG1524@1,COG1524@2 NA|NA|NA S type I phosphodiesterase nucleotide pyrophosphatase gnl|extdb|FAM14217-p1-1.1_001398 754252.PFREUD_12760 3.3e-186 657.9 Propionibacteriales GO:0008150,GO:0040007 Bacteria 28PUQ@1,2GNQM@201174,2ZCFK@2,4DR1M@85009 NA|NA|NA S Protein of unknown function (DUF3071) gnl|extdb|FAM14217-p1-1.1_001400 1122994.AUFR01000016_gene1863 3.4e-10 70.9 Actinobacteria Bacteria 2DR0Y@1,2GWIF@201174,339QH@2 NA|NA|NA S Protein of unknown function (DUF4235) gnl|extdb|FAM14217-p1-1.1_001401 754252.PFREUD_12730 1.4e-115 422.5 Propionibacteriales Bacteria 28J4D@1,2GJYC@201174,2Z90C@2,4DRF5@85009 NA|NA|NA S Protein of unknown function (DUF3710) gnl|extdb|FAM14217-p1-1.1_001403 754252.PFREUD_12710 1e-119 436.0 Propionibacteriales trkA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2GKB9@201174,4DN0P@85009,COG0569@1,COG0569@2 NA|NA|NA P TrkA-C domain gnl|extdb|FAM14217-p1-1.1_001405 754252.PFREUD_12690 0.0 1247.6 Propionibacteriales ydaO Bacteria 2GK5V@201174,4DP47@85009,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM14217-p1-1.1_001408 1171373.PACID_02490 7.4e-152 543.5 Propionibacteriales Bacteria 2GIXK@201174,4DNXR@85009,COG0435@1,COG0435@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain gnl|extdb|FAM14217-p1-1.1_001409 754252.PFREUD_12640 4.1e-121 440.7 Actinobacteria Bacteria 2IQC7@201174,COG0454@1,COG0456@2 NA|NA|NA K PFAM GCN5-related N-acetyltransferase gnl|extdb|FAM14217-p1-1.1_001411 754252.PFREUD_12610 3.3e-202 710.7 Propionibacteriales 1.8.5.7 ko:K07393 ko00000,ko01000 Bacteria 2GIXK@201174,4DNXR@85009,COG0435@1,COG0435@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain gnl|extdb|FAM14217-p1-1.1_001412 754252.PFREUD_12600 2.5e-240 837.8 Actinobacteria ko:K03761,ko:K03762 ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 Bacteria 2GIYR@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily gnl|extdb|FAM14217-p1-1.1_001413 754252.PFREUD_12590 0.0 1797.3 Propionibacteriales acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJD5@201174,4DPP4@85009,COG1048@1,COG1048@2 NA|NA|NA C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate gnl|extdb|FAM14217-p1-1.1_001414 754252.PFREUD_12580 1.3e-50 205.3 Bacteria Bacteria COG4367@1,COG4367@2 NA|NA|NA K negative regulation of transcription, DNA-templated gnl|extdb|FAM14217-p1-1.1_001415 754252.PFREUD_12570 3.6e-91 340.9 Actinobacteria Bacteria 2E8DB@1,2IHS0@201174,332RT@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001416 754252.PFREUD_12560 0.0 1325.8 Propionibacteriales dxs GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_0456,iIT341.HP0354,iJN746.PP_0527 Bacteria 2GMFA@201174,4DNP5@85009,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) gnl|extdb|FAM14217-p1-1.1_001418 754252.PFREUD_12540 4.9e-113 413.7 Propionibacteriales Bacteria 2AIF4@1,2GK8R@201174,318WM@2,4DQE6@85009 NA|NA|NA S Protein of unknown function (DUF3000) gnl|extdb|FAM14217-p1-1.1_001419 754252.PFREUD_12530 1.3e-81 309.3 Propionibacteriales ko:K03976,ko:K19055 ko00000,ko01000,ko03016 Bacteria 2GKUX@201174,4DR3S@85009,COG2606@1,COG2606@2 NA|NA|NA S Aminoacyl-tRNA editing domain gnl|extdb|FAM14217-p1-1.1_001420 754252.PFREUD_12520 1.4e-88 332.0 Propionibacteriales msrB 1.8.4.12 ko:K07305 ko00000,ko01000 Bacteria 2IHV0@201174,4DQU8@85009,COG0229@1,COG0229@2 NA|NA|NA O Peptide-methionine (R)-S-oxide reductase gnl|extdb|FAM14217-p1-1.1_001421 754252.PFREUD_12510 2.3e-172 611.3 Propionibacteriales 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GKRN@201174,4DNFS@85009,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) gnl|extdb|FAM14217-p1-1.1_001422 754252.PFREUD_12500 1.6e-149 535.4 Propionibacteriales Bacteria 2GS51@201174,4DQ03@85009,COG2138@1,COG2138@2 NA|NA|NA S CbiX gnl|extdb|FAM14217-p1-1.1_001428 754252.PFREUD_12430 6e-115 420.2 Propionibacteriales hit GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 ko:K19710 ko00230,map00230 R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 Bacteria 2GJT5@201174,4DQ7R@85009,COG0537@1,COG0537@2 NA|NA|NA FG HIT domain gnl|extdb|FAM14217-p1-1.1_001429 754252.PFREUD_12420 5.9e-109 400.2 Propionibacteriales pgsA1 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 ko:K00995,ko:K00999 ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070 R01801,R01802 RC00002,RC00017,RC00078,RC02795 ko00000,ko00001,ko01000 Bacteria 2GYKW@201174,4DP2F@85009,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family gnl|extdb|FAM14217-p1-1.1_001430 754252.PFREUD_12410 1.2e-168 599.0 Bacteria htrB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 ko:K02517,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria COG1560@1,COG1560@2 NA|NA|NA M Kdo2-lipid A biosynthetic process gnl|extdb|FAM14217-p1-1.1_001431 754252.PFREUD_12400 3.7e-218 763.8 Propionibacteriales pimA GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 ko:K08256 R11702 ko00000,ko01000,ko01003 GT4 Bacteria 2GKQ8@201174,4DNV1@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM14217-p1-1.1_001434 754252.PFREUD_12370 2e-47 194.9 Propionibacteriales sbp Bacteria 2IKJW@201174,4DR0I@85009,COG3856@1,COG3856@2 NA|NA|NA S Protein of unknown function (DUF1290) gnl|extdb|FAM14217-p1-1.1_001436 754252.PFREUD_12350 2.1e-64 251.5 Propionibacteriales gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 iNJ661.Rv1826 Bacteria 2IKN2@201174,4DR4B@85009,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gnl|extdb|FAM14217-p1-1.1_001437 754252.PFREUD_12340 6.9e-89 333.2 Propionibacteriales Bacteria 2GK99@201174,4DR1A@85009,COG1716@1,COG1716@2 NA|NA|NA T zinc-ribbon domain gnl|extdb|FAM14217-p1-1.1_001438 754252.PFREUD_12330 9.6e-127 459.5 Propionibacteriales merR1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 Bacteria 2HBV6@201174,4DQDI@85009,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM14217-p1-1.1_001439 754252.PFREUD_12320 1.8e-78 298.5 Bacteria GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03617,ko:K08999 ko00000 Bacteria COG1259@1,COG1259@2 NA|NA|NA K PFAM Uncharacterised ACR, COG1259 gnl|extdb|FAM14217-p1-1.1_001440 754252.PFREUD_12310 4.7e-103 380.6 Propionibacteriales merR2 Bacteria 2GM67@201174,4DPQ2@85009,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM14217-p1-1.1_001441 754252.PFREUD_12300 0.0 1932.5 Propionibacteriales gcvP GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3318 Bacteria 2GJ11@201174,4DNP8@85009,COG0403@1,COG0403@2,COG1003@1,COG1003@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gnl|extdb|FAM14217-p1-1.1_001442 754252.PFREUD_12280 1.5e-261 908.3 Propionibacteriales yhjD GO:0003674,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015920,GO:0016020,GO:0016021,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0033036,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1901264,GO:1901505 ko:K07058 ko00000 Bacteria 2GN79@201174,4DS0K@85009,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB gnl|extdb|FAM14217-p1-1.1_001445 754252.PFREUD_12250 1.6e-106 392.1 Propionibacteriales Bacteria 2GQPK@201174,4DR62@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM14217-p1-1.1_001446 754252.PFREUD_12240 2.8e-137 494.6 Actinobacteria cobS GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 ko:K02233 ko00860,ko01100,map00860,map01100 M00122 R05223,R11174 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKM4@201174,COG0368@1,COG0368@2 NA|NA|NA H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate gnl|extdb|FAM14217-p1-1.1_001447 754252.PFREUD_12230 1.4e-124 452.2 Propionibacteriales cobU 2.4.2.21,2.7.1.156,2.7.7.62 ko:K00768,ko:K02231 ko00860,ko01100,map00860,map01100 M00122 R04148,R05221,R05222,R06558 RC00002,RC00033,RC00063,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM8Q@201174,4DQRD@85009,COG2087@1,COG2087@2 NA|NA|NA H Cobinamide kinase / cobinamide phosphate guanyltransferase gnl|extdb|FAM14217-p1-1.1_001448 754252.PFREUD_12220 0.0 1721.4 Propionibacteriales cobB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.6.1.9,4.1.1.81,6.3.5.11,6.3.5.9 ko:K00817,ko:K02224,ko:K04720 ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01120,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01120,map01130,map01230 M00026 R00694,R00734,R03243,R05224,R05815,R06530 RC00006,RC00010,RC00517,RC00888,RC01301 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ3R@201174,4DN94@85009,COG0079@1,COG0079@2,COG1797@1,COG1797@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source gnl|extdb|FAM14217-p1-1.1_001449 754252.PFREUD_12210 7.6e-114 416.4 Propionibacteriales cobO 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2849c Bacteria 2GNJQ@201174,4DNYI@85009,COG2109@1,COG2109@2 NA|NA|NA H ATP:corrinoid adenosyltransferase BtuR/CobO/CobP gnl|extdb|FAM14217-p1-1.1_001450 754252.PFREUD_12200 8.9e-278 962.2 Propionibacteriales cobQ GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS15780,iJN678.cbiP,iYL1228.KPN_03184 Bacteria 2GJ1W@201174,4DPU3@85009,COG1492@1,COG1492@2 NA|NA|NA H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation gnl|extdb|FAM14217-p1-1.1_001451 754252.PFREUD_12190 2.6e-205 721.1 Propionibacteriales cobD 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMB8@201174,4DNIT@85009,COG1270@1,COG1270@2 NA|NA|NA H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group gnl|extdb|FAM14217-p1-1.1_001452 754252.PFREUD_12180 5.4e-93 347.1 Bacteria 3.1.3.85,5.4.2.11,5.4.2.12 ko:K01834,ko:K15634,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria COG0406@1,COG0406@2 NA|NA|NA G alpha-ribazole phosphatase activity gnl|extdb|FAM14217-p1-1.1_001454 754252.PFREUD_12160 3e-156 557.8 Propionibacteriales otsB 3.1.3.12 ko:K01087 ko00500,ko01100,map00500,map01100 R02778 RC00017 ko00000,ko00001,ko01000 Bacteria 2GMKW@201174,4DNQI@85009,COG1877@1,COG1877@2 NA|NA|NA G Removes the phosphate from trehalose 6-phosphate to produce free trehalose gnl|extdb|FAM14217-p1-1.1_001458 754252.PFREUD_12120 3e-173 614.4 Propionibacteriales Bacteria 2HEZY@201174,4DQGC@85009,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase gnl|extdb|FAM14217-p1-1.1_001459 754252.PFREUD_12110 1.6e-274 951.4 Actinobacteria ko:K03086 ko00000,ko03021 Bacteria 2H4XN@201174,COG0568@1,COG0568@2 NA|NA|NA K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released gnl|extdb|FAM14217-p1-1.1_001460 754252.PFREUD_12100 1.7e-45 188.3 Bacteria Bacteria COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity gnl|extdb|FAM14217-p1-1.1_001461 754252.PFREUD_12090 1.1e-132 479.2 Actinobacteria thiD 2.5.1.3,2.7.1.49,2.7.4.7,3.5.99.2 ko:K00941,ko:K03707,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R02133,R03223,R03471,R04509,R09993,R10712 RC00002,RC00017,RC00224,RC00652,RC02832,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2IA0S@201174,COG0819@1,COG0819@2 NA|NA|NA K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway gnl|extdb|FAM14217-p1-1.1_001462 754252.PFREUD_12080 0.0 1250.3 Propionibacteriales dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFX@201174,4DN6K@85009,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication gnl|extdb|FAM14217-p1-1.1_001463 754252.PFREUD_12070 7.8e-146 523.1 Bacteria ko:K03086,ko:K03087,ko:K03093 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria COG0568@1,COG0568@2 NA|NA|NA K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released gnl|extdb|FAM14217-p1-1.1_001464 754252.PFREUD_12060 1.4e-98 365.5 Bacteria Bacteria 2EFFR@1,3398G@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001466 754252.PFREUD_12040 2.2e-229 801.2 Propionibacteriales pfp 2.7.1.90 ko:K00895 ko00010,ko00030,ko00051,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map01100,map01110,map01120,map01130 R00764,R02073 RC00017 ko00000,ko00001,ko01000 Bacteria 2GK6W@201174,4DPPT@85009,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions gnl|extdb|FAM14217-p1-1.1_001467 1380356.JNIK01000001_gene2282 2e-07 62.4 Frankiales Bacteria 2E4ST@1,2GSCH@201174,32ZM5@2,4ETEF@85013 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001468 754252.PFREUD_12020 1e-113 416.0 Propionibacteriales yciO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2GNEW@201174,4DNCR@85009,COG0009@1,COG0009@2 NA|NA|NA J Belongs to the SUA5 family gnl|extdb|FAM14217-p1-1.1_001469 754252.PFREUD_12010 3e-98 365.2 Actinobacteria gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 2GJYG@201174,COG0705@1,COG0705@2 NA|NA|NA NU Rhomboid family gnl|extdb|FAM14217-p1-1.1_001470 754252.PFREUD_12000 5.3e-155 553.5 Propionibacteriales Bacteria 2GIUS@201174,4DREC@85009,COG2120@1,COG2120@2 NA|NA|NA S GlcNAc-PI de-N-acetylase gnl|extdb|FAM14217-p1-1.1_001471 754252.PFREUD_11990 8.9e-195 686.0 Propionibacteriales pac ko:K07184 ko00000 Bacteria 2I2N7@201174,4DQ83@85009,COG1938@1,COG1938@2 NA|NA|NA S PAC2 family gnl|extdb|FAM14217-p1-1.1_001472 754252.PFREUD_11980 6.9e-139 500.0 Propionibacteriales ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 2GNP6@201174,4DUW4@85009,COG1101@1,COG1101@2 NA|NA|NA S ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_001473 754252.PFREUD_11970 8.5e-160 569.7 Actinobacteria ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 2I8VW@201174,COG4120@1,COG4120@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family gnl|extdb|FAM14217-p1-1.1_001474 754252.PFREUD_11960 5e-163 580.5 Actinobacteria ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 2GKNV@201174,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter substrate-binding protein gnl|extdb|FAM14217-p1-1.1_001475 754252.PFREUD_11950 4.6e-122 443.7 Actinobacteria 3.1.3.73,3.1.3.85 ko:K02226,ko:K22306 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2I9GN@201174,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase gnl|extdb|FAM14217-p1-1.1_001476 754252.PFREUD_11940 0.0 1180.2 Actinobacteria glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECIAI39_1322.ECIAI39_0637 Bacteria 2H1TZ@201174,COG0008@1,COG0008@2 NA|NA|NA J tRNA synthetases class I (E and Q), anti-codon binding domain gnl|extdb|FAM14217-p1-1.1_001477 754252.PFREUD_11930 1.1e-129 469.2 Propionibacteriales 1.17.1.9,1.7.7.2 ko:K00123,ko:K00367,ko:K18558 ko00630,ko00680,ko00720,ko00910,ko01100,ko01120,ko01200,map00630,map00680,map00720,map00910,map01100,map01120,map01200 M00173,M00531 R00402,R00519,R00791 RC00045,RC02796,RC02812 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ62@201174,4DR20@85009,COG0243@1,COG0243@2 NA|NA|NA C molybdopterin cofactor binding gnl|extdb|FAM14217-p1-1.1_001480 754252.PFREUD_11900 2.5e-150 538.1 Propionibacteriales trpC 4.1.1.48,5.1.3.9 ko:K01609,ko:K01788 ko00400,ko00520,ko01100,ko01110,ko01130,ko01230,map00400,map00520,map01100,map01110,map01130,map01230 M00023 R02087,R03508 RC00290,RC00944 ko00000,ko00001,ko00002,ko01000 Bacteria 2I4VZ@201174,4DX2K@85009,COG3010@1,COG3010@2 NA|NA|NA E Belongs to the TrpC family gnl|extdb|FAM14217-p1-1.1_001481 754252.PFREUD_11890 2.4e-239 834.3 Propionibacteriales trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM7Z@201174,4DN45@85009,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine gnl|extdb|FAM14217-p1-1.1_001482 754252.PFREUD_11880 1.7e-165 588.6 Propionibacteriales trpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN6T@201174,4DNGE@85009,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate gnl|extdb|FAM14217-p1-1.1_001483 754252.PFREUD_11870 1.1e-189 669.1 Propionibacteriales lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 2GKSS@201174,4DP3T@85009,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins gnl|extdb|FAM14217-p1-1.1_001484 754252.PFREUD_11860 0.0 2982.2 Propionibacteriales gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 2GN09@201174,4DP8G@85009,COG0067@1,COG0067@2,COG0069@1,COG0069@2 NA|NA|NA E GXGXG motif gnl|extdb|FAM14217-p1-1.1_001485 754252.PFREUD_11850 4.2e-291 1006.5 Propionibacteriales gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 2GJ0A@201174,4DNI1@85009,COG0493@1,COG0493@2 NA|NA|NA E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gnl|extdb|FAM14217-p1-1.1_001486 754252.PFREUD_11840 1.2e-104 386.0 Bacteria Bacteria COG3247@1,COG3247@2 NA|NA|NA U response to pH gnl|extdb|FAM14217-p1-1.1_001487 754252.PFREUD_11830 0.0 2397.5 Propionibacteriales dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ1P@201174,4DTRE@85009,COG0587@1,COG0587@2 NA|NA|NA L Bacterial DNA polymerase III alpha subunit gnl|extdb|FAM14217-p1-1.1_001488 754252.PFREUD_11820 3.3e-132 477.6 Propionibacteriales Bacteria 2DVYJ@1,2HZGU@201174,33XQ4@2,4DSRP@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001489 754252.PFREUD_11810 3e-90 337.8 Propionibacteriales ybaK GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K03976 ko00000,ko01000,ko03016 Bacteria 2IHS8@201174,4DQRV@85009,COG2606@1,COG2606@2 NA|NA|NA S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily gnl|extdb|FAM14217-p1-1.1_001490 754252.PFREUD_11800 1.6e-129 468.8 Propionibacteriales ydfK ko:K07150 ko00000 Bacteria 2GM75@201174,4DPPY@85009,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) gnl|extdb|FAM14217-p1-1.1_001491 754252.PFREUD_11790 2.8e-238 830.9 Propionibacteriales hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1599 Bacteria 2GKKA@201174,4DMY2@85009,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine gnl|extdb|FAM14217-p1-1.1_001492 754252.PFREUD_11780 1.2e-227 795.4 Propionibacteriales hisC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ9W@201174,4DPP5@85009,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily gnl|extdb|FAM14217-p1-1.1_001493 754252.PFREUD_11770 1.3e-100 372.5 Propionibacteriales hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 2GKMD@201174,4DNSZ@85009,COG0131@1,COG0131@2 NA|NA|NA E Imidazoleglycerol-phosphate dehydratase gnl|extdb|FAM14217-p1-1.1_001494 754252.PFREUD_11760 4e-127 460.7 Propionibacteriales hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIYS@201174,4DPJU@85009,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR gnl|extdb|FAM14217-p1-1.1_001495 754252.PFREUD_11750 6.3e-131 473.4 Propionibacteriales hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4V@201174,4DMXV@85009,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase gnl|extdb|FAM14217-p1-1.1_001496 754252.PFREUD_11740 7.7e-207 726.1 Bacteria ko:K18566 ko00332,ko01130,map00332,map01130 R10745,R10746 RC00004,RC00096 ko00000,ko00001,ko01000 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase gnl|extdb|FAM14217-p1-1.1_001497 754252.PFREUD_11730 2.4e-131 474.9 Propionibacteriales yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2GJ4G@201174,4DN3U@85009,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein gnl|extdb|FAM14217-p1-1.1_001498 754252.PFREUD_11720 5.2e-86 323.9 Propionibacteriales ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJI5@201174,4DQAA@85009,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group gnl|extdb|FAM14217-p1-1.1_001499 754252.PFREUD_11710 7.7e-106 389.8 Propionibacteriales ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GN17@201174,4DQ7Y@85009,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB gnl|extdb|FAM14217-p1-1.1_001500 754252.PFREUD_11700 5e-190 670.2 Propionibacteriales ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJZF@201174,4DP63@85009,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing gnl|extdb|FAM14217-p1-1.1_001501 754252.PFREUD_11690 3.4e-83 314.3 Propionibacteriales yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GXK0@201174,4DSPJ@85009,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase subunit gnl|extdb|FAM14217-p1-1.1_001502 754252.PFREUD_11680 6.6e-288 996.1 Propionibacteriales secD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2GJTT@201174,4DP94@85009,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA gnl|extdb|FAM14217-p1-1.1_001503 754252.PFREUD_11670 1.2e-217 762.3 Propionibacteriales secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2GJRS@201174,4DPBJ@85009,COG0341@1,COG0341@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA gnl|extdb|FAM14217-p1-1.1_001504 754252.PFREUD_11660 5.6e-92 343.6 Actinobacteria apt 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 2IM7C@201174,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis gnl|extdb|FAM14217-p1-1.1_001505 754252.PFREUD_11650 0.0 1562.7 Propionibacteriales relA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 Bacteria 2GJYQ@201174,4DNJH@85009,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance gnl|extdb|FAM14217-p1-1.1_001506 754252.PFREUD_11640 1.2e-222 778.9 Propionibacteriales Bacteria 2GJBD@201174,4DNC8@85009,COG1196@1,COG1196@2 NA|NA|NA D Domain of Unknown Function (DUF349) gnl|extdb|FAM14217-p1-1.1_001507 754252.PFREUD_11630 1.2e-129 469.2 Propionibacteriales ycbL 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 2GJU0@201174,4DNMS@85009,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily gnl|extdb|FAM14217-p1-1.1_001508 754252.PFREUD_11620 4.1e-253 880.2 Propionibacteriales hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIYJ@201174,4DP1N@85009,COG0124@1,COG0124@2 NA|NA|NA J Histidine--tRNA ligase gnl|extdb|FAM14217-p1-1.1_001509 754252.PFREUD_11610 1.9e-152 545.0 Actinobacteria budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 2IBRH@201174,COG3527@1,COG3527@2 NA|NA|NA Q Belongs to the alpha-acetolactate decarboxylase family gnl|extdb|FAM14217-p1-1.1_001510 754252.PFREUD_11600 1.5e-205 721.8 Actinobacteria Bacteria 28IW2@1,2IA78@201174,2Z8UC@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001511 754252.PFREUD_11590 0.0 1246.5 Propionibacteriales aspS GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJHU@201174,4DPC4@85009,COG0173@1,COG0173@2 NA|NA|NA J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) gnl|extdb|FAM14217-p1-1.1_001512 754252.PFREUD_11580 9.2e-259 899.0 Propionibacteriales rarA ko:K07478 ko00000 Bacteria 2GKDP@201174,4DP5Q@85009,COG2256@1,COG2256@2 NA|NA|NA L MgsA AAA+ ATPase C terminal gnl|extdb|FAM14217-p1-1.1_001513 754252.PFREUD_11570 1.5e-183 648.7 Actinobacteria ldh1 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 2H3WC@201174,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily gnl|extdb|FAM14217-p1-1.1_001514 754252.PFREUD_11560 0.0 1780.0 Propionibacteriales alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIUG@201174,4DP1M@85009,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain gnl|extdb|FAM14217-p1-1.1_001515 754252.PFREUD_11550 1.9e-95 355.1 Propionibacteriales yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 2IQB0@201174,4DR7E@85009,COG0816@1,COG0816@2 NA|NA|NA L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA gnl|extdb|FAM14217-p1-1.1_001516 754252.PFREUD_11540 2.3e-229 801.2 Propionibacteriales mltG ko:K07082 ko00000 Bacteria 2GKGQ@201174,4DN3K@85009,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation gnl|extdb|FAM14217-p1-1.1_001517 754252.PFREUD_11530 3.1e-223 780.8 Propionibacteriales aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976 Bacteria 2GJJN@201174,4DPU4@85009,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system gnl|extdb|FAM14217-p1-1.1_001518 754252.PFREUD_11520 2.1e-310 1070.8 Propionibacteriales aroB GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIUZ@201174,4DN6F@85009,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) gnl|extdb|FAM14217-p1-1.1_001519 754252.PFREUD_11510 2e-103 381.7 Actinobacteria efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 2GJMS@201174,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase gnl|extdb|FAM14217-p1-1.1_001520 754252.PFREUD_11500 2.2e-108 398.3 Actinobacteria nusB GO:0008150,GO:0040007 ko:K03625 ko00000,ko03009,ko03021 Bacteria 2IM3D@201174,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons gnl|extdb|FAM14217-p1-1.1_001521 754252.PFREUD_11480 2.2e-226 791.2 Propionibacteriales carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1950,iNJ661.Rv1383,iUTI89_1310.UTI89_C0036,iYO844.BSU15510,ic_1306.c0040 Bacteria 2GKFA@201174,4DNY4@85009,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family gnl|extdb|FAM14217-p1-1.1_001522 754252.PFREUD_11470 0.0 2200.2 Propionibacteriales carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 Bacteria 2GK5N@201174,4DNSQ@85009,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthetase ammonia chain gnl|extdb|FAM14217-p1-1.1_001523 754252.PFREUD_11460 3.3e-208 730.7 Propionibacteriales pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 Bacteria 2GKC6@201174,4DP48@85009,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor gnl|extdb|FAM14217-p1-1.1_001524 754252.PFREUD_11450 1.7e-148 531.9 Propionibacteriales pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 2GKWK@201174,4DNH0@85009,COG0284@1,COG0284@2 NA|NA|NA F Belongs to the OMP decarboxylase family. Type 2 subfamily gnl|extdb|FAM14217-p1-1.1_001525 754252.PFREUD_11440 3.4e-49 200.7 Propionibacteriales mihF 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2IKPU@201174,4DRRY@85009,COG0099@1,COG0099@2 NA|NA|NA J integration host factor gnl|extdb|FAM14217-p1-1.1_001526 754252.PFREUD_11430 4.6e-114 417.2 Propionibacteriales gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2GK2M@201174,4DQBB@85009,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP gnl|extdb|FAM14217-p1-1.1_001527 754252.PFREUD_11420 4.7e-58 230.3 Propionibacteriales rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IQHU@201174,4DRNP@85009,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gnl|extdb|FAM14217-p1-1.1_001528 754252.PFREUD_11410 5.9e-219 766.5 Propionibacteriales metK GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4U@201174,4DN34@85009,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme gnl|extdb|FAM14217-p1-1.1_001529 754252.PFREUD_11400 0.0 1340.5 Propionibacteriales priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKES@201174,4DNMW@85009,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA gnl|extdb|FAM14217-p1-1.1_001530 754252.PFREUD_11390 4e-178 630.6 Propionibacteriales fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 ko:K00604,ko:K03500 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000,ko03009 iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Bacteria 2GKH5@201174,4DN9I@85009,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus gnl|extdb|FAM14217-p1-1.1_001531 754252.PFREUD_11380 4e-257 893.6 Propionibacteriales sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,5.3.1.9 ko:K01810,ko:K03500 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2GM21@201174,4DP4E@85009,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA JK Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family gnl|extdb|FAM14217-p1-1.1_001532 754252.PFREUD_11370 1.3e-117 429.1 Propionibacteriales rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZ9@201174,4DNZI@85009,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family gnl|extdb|FAM14217-p1-1.1_001533 754252.PFREUD_11360 1.6e-260 904.8 Propionibacteriales pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 2GNYU@201174,4DQ4H@85009,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family gnl|extdb|FAM14217-p1-1.1_001534 754252.PFREUD_11350 1.8e-158 565.1 Propionibacteriales ko:K07159 ko00000 Bacteria 2I2H9@201174,4DWGD@85009,COG2047@1,COG2047@2 NA|NA|NA S PAC2 family gnl|extdb|FAM14217-p1-1.1_001535 754252.PFREUD_11340 0.0 2300.8 Actinobacteria metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM5Q@201174,COG0646@1,COG0646@2,COG1410@1,COG1410@2 NA|NA|NA E Methionine synthase gnl|extdb|FAM14217-p1-1.1_001536 754252.PFREUD_11330 1.7e-179 635.6 Bacteria sppA ko:K04773,ko:K21511 ko00000,ko01000,ko01002 Bacteria COG0616@1,COG0616@2 NA|NA|NA OU serine-type peptidase activity gnl|extdb|FAM14217-p1-1.1_001538 754252.PFREUD_11300 1.6e-154 552.0 Propionibacteriales prcB GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 ko:K03433 ko03050,map03050 M00342,M00343 ko00000,ko00001,ko00002,ko01000,ko01002,ko03051 Bacteria 2GJ60@201174,4DPD6@85009,COG0638@1,COG0638@2 NA|NA|NA O Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation gnl|extdb|FAM14217-p1-1.1_001539 754252.PFREUD_11290 5.7e-132 476.9 Propionibacteriales prcA GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 ko:K03432 ko03050,map03050 M00342,M00343 ko00000,ko00001,ko00002,ko01000,ko01002,ko03051 Bacteria 2GKZ1@201174,4DMZ3@85009,COG0638@1,COG0638@2 NA|NA|NA O Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation gnl|extdb|FAM14217-p1-1.1_001540 754252.PFREUD_11280 1.1e-200 705.7 Propionibacteriales tyrA 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKB4@201174,4DNB5@85009,COG0287@1,COG0287@2 NA|NA|NA E Prephenate dehydrogenase gnl|extdb|FAM14217-p1-1.1_001541 754252.PFREUD_11270 6.7e-119 433.3 Actinobacteria cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945,ko:K03977 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2H3SI@201174,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily gnl|extdb|FAM14217-p1-1.1_001542 754252.PFREUD_11260 1.3e-251 875.2 Propionibacteriales der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2GJ8J@201174,4DNFK@85009,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis gnl|extdb|FAM14217-p1-1.1_001543 754252.PFREUD_11250 8.7e-95 352.8 Bacteria M1-431 Bacteria COG4283@1,COG4283@2 NA|NA|NA S Protein of unknown function (DUF1706) gnl|extdb|FAM14217-p1-1.1_001545 754252.PFREUD_11220 1.4e-101 375.6 Actinobacteria Bacteria 2IR1F@201174,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_001547 754252.PFREUD_11200 6.6e-151 540.0 Actinobacteria rhtA_1 ko:K11939 ko00000,ko02000 2.A.7.3.6 Bacteria 2GJKB@201174,COG5006@1,COG5006@2 NA|NA|NA K permease, DMT superfamily gnl|extdb|FAM14217-p1-1.1_001549 754252.PFREUD_11180 7.4e-49 199.5 Bacteria marR5 Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM14217-p1-1.1_001550 754252.PFREUD_11170 6.7e-309 1066.2 Actinobacteria Bacteria 2BBT7@1,2H2DB@201174,325BF@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001551 754252.PFREUD_11160 4.3e-283 979.9 Propionibacteriales Bacteria 2E9GW@1,2IEUC@201174,333PY@2,4DWDI@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001552 754252.PFREUD_11150 0.0 1686.8 Actinobacteria Bacteria 2HVT3@201174,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family gnl|extdb|FAM14217-p1-1.1_001553 754252.PFREUD_11140 5.7e-172 610.1 Actinobacteria Bacteria 2GN05@201174,COG0464@1,COG0464@2 NA|NA|NA O ATPase family associated with various cellular activities (AAA) gnl|extdb|FAM14217-p1-1.1_001554 754252.PFREUD_11130 2.2e-51 208.0 Propionibacteriales Bacteria 2DWAA@1,2HZZ2@201174,33Z9V@2,4DWAI@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001555 1122175.ATXU01000014_gene222 0.0 1681.8 Microbacteriaceae Bacteria 2GJRK@201174,4FKPJ@85023,COG0507@1,COG0507@2 NA|NA|NA L TrwC relaxase gnl|extdb|FAM14217-p1-1.1_001558 754252.PFREUD_11090 2.1e-113 414.8 Propionibacteriales Bacteria 28Q31@1,2IFAQ@201174,2ZCKT@2,4DR3P@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001562 754252.PFREUD_11050 2.3e-86 324.7 Actinobacteria luxS GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJVF@201174,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) gnl|extdb|FAM14217-p1-1.1_001564 754252.PFREUD_11030 6.5e-154 550.1 Propionibacteriales GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2GKKZ@201174,4DWQU@85009,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_001565 754252.PFREUD_11020 1.2e-172 612.5 Propionibacteriales ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2HFVC@201174,4DSW7@85009,COG0715@1,COG0715@2 NA|NA|NA P NMT1/THI5 like gnl|extdb|FAM14217-p1-1.1_001567 754252.PFREUD_11000 1.7e-237 828.2 Propionibacteriales metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 2GKNJ@201174,4DNSW@85009,COG2021@1,COG2021@2 NA|NA|NA E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine gnl|extdb|FAM14217-p1-1.1_001568 754252.PFREUD_10990 4.4e-126 457.2 Propionibacteriales metW 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 2IDZY@201174,4DUY7@85009,COG0500@1,COG2226@2 NA|NA|NA Q Methionine biosynthesis protein MetW gnl|extdb|FAM14217-p1-1.1_001569 754252.PFREUD_10980 6.3e-70 270.4 Propionibacteriales lrp_3 ko:K03719 ko00000,ko03000,ko03036 Bacteria 2GK3G@201174,4DQJS@85009,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type gnl|extdb|FAM14217-p1-1.1_001570 754252.PFREUD_10970 5.7e-305 1052.7 Propionibacteriales lnt GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K03820 ko00000,ko01000 GT2 iNJ661.Rv2051c Bacteria 2GJ9F@201174,4DP6S@85009,COG0815@1,COG0815@2 NA|NA|NA M Transfers the fatty acyl group on membrane lipoproteins gnl|extdb|FAM14217-p1-1.1_001571 754252.PFREUD_10950 2.6e-149 534.6 Propionibacteriales dpm1 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 2I2FA@201174,4DNYS@85009,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 gnl|extdb|FAM14217-p1-1.1_001572 754252.PFREUD_10940 1.8e-59 235.0 Propionibacteriales rbpA GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 2CNY9@1,2IMK6@201174,32SI2@2,4DQUX@85009 NA|NA|NA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters gnl|extdb|FAM14217-p1-1.1_001574 1122994.AUFR01000001_gene1494 5.4e-36 157.5 Propionibacteriales Bacteria 2B5VP@1,2I057@201174,31YRJ@2,4DVSR@85009 NA|NA|NA S Putative transmembrane protein (PGPGW) gnl|extdb|FAM14217-p1-1.1_001575 754252.PFREUD_10910 8.6e-159 566.2 Propionibacteriales pdxY GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008478,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042817,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_1723 Bacteria 2HS59@201174,4DNVS@85009,COG2240@1,COG2240@2 NA|NA|NA H Belongs to the pyridoxine kinase family gnl|extdb|FAM14217-p1-1.1_001576 754252.PFREUD_10900 9.2e-289 998.8 Propionibacteriales murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJPW@201174,4DP2I@85009,COG0766@1,COG0766@2 NA|NA|NA M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) gnl|extdb|FAM14217-p1-1.1_001577 754252.PFREUD_10890 1.6e-263 914.8 Propionibacteriales lpdA 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GIXY@201174,4DNBU@85009,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM14217-p1-1.1_001578 754252.PFREUD_10880 6.2e-213 746.5 Propionibacteriales livJ ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GM00@201174,4DQP9@85009,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region gnl|extdb|FAM14217-p1-1.1_001579 754252.PFREUD_10870 4.6e-152 543.9 Actinobacteria livH ko:K01997 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GMAY@201174,COG0559@1,COG0559@2 NA|NA|NA E Belongs to the binding-protein-dependent transport system permease family gnl|extdb|FAM14217-p1-1.1_001580 754252.PFREUD_10860 9.7e-162 576.2 Propionibacteriales livM ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GMGD@201174,4DNIE@85009,COG4177@1,COG4177@2 NA|NA|NA E Branched-chain amino acid transport system / permease component gnl|extdb|FAM14217-p1-1.1_001581 754252.PFREUD_10850 5.4e-144 516.9 Propionibacteriales livG ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GMEE@201174,4DPPJ@85009,COG0411@1,COG0411@2 NA|NA|NA E Amino acid amide ABC transporter ATP-binding protein 1, HAAT family gnl|extdb|FAM14217-p1-1.1_001582 754252.PFREUD_10840 6.8e-122 443.4 Propionibacteriales livF ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GKSQ@201174,4DPMH@85009,COG0410@1,COG0410@2 NA|NA|NA E ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_001583 754252.PFREUD_10830 4.8e-114 417.2 Actinobacteria acuB ko:K04767 ko00000 Bacteria 2GSAR@201174,COG0517@1,COG0517@2 NA|NA|NA S Cbs domain gnl|extdb|FAM14217-p1-1.1_001584 754252.PFREUD_10820 3.3e-71 274.2 Bacteria manX 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria COG2893@1,COG2893@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system gnl|extdb|FAM14217-p1-1.1_001585 754252.PFREUD_10810 4.9e-215 753.4 Propionibacteriales pepE 3.4.13.9 ko:K01271,ko:K01274 ko00000,ko01000,ko01002 Bacteria 2GM7D@201174,4DNDZ@85009,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain gnl|extdb|FAM14217-p1-1.1_001586 1122994.AUFR01000001_gene1486 2e-119 436.0 Actinobacteria Bacteria 2GP6Q@201174,COG0627@1,COG0627@2 NA|NA|NA S Esterase gnl|extdb|FAM14217-p1-1.1_001587 754252.PFREUD_10780 0.0 1291.9 Actinobacteria Bacteria 2GM2C@201174,COG2898@1,COG2898@2 NA|NA|NA S Uncharacterised conserved protein (DUF2156) gnl|extdb|FAM14217-p1-1.1_001588 1122994.AUFR01000001_gene1485 4.2e-08 65.1 Actinobacteria 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 2GM2C@201174,COG0705@1,COG0705@2,COG2898@1,COG2898@2 NA|NA|NA S Uncharacterised conserved protein (DUF2156) gnl|extdb|FAM14217-p1-1.1_001590 754252.PFREUD_10760 3.4e-283 980.3 Propionibacteriales gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJK5@201174,4DN5B@85009,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gnl|extdb|FAM14217-p1-1.1_001591 754252.PFREUD_10750 1.2e-46 192.2 Bacteria gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gnl|extdb|FAM14217-p1-1.1_001592 754252.PFREUD_10740 5.5e-115 420.2 Propionibacteriales ilvA 1.3.1.12,4.3.1.19 ko:K01754,ko:K04517 ko00260,ko00290,ko00400,ko00401,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map00400,map00401,map01100,map01110,map01130,map01200,map01230 M00025,M00570 R00220,R00996,R01728 RC00125,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 2I3KF@201174,4DR5N@85009,COG2061@1,COG2061@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA gnl|extdb|FAM14217-p1-1.1_001594 754252.PFREUD_10720 2e-167 595.1 Propionibacteriales 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMPS@201174,4DN0J@85009,COG0620@1,COG0620@2 NA|NA|NA E Methionine synthase, vitamin-B12 independent gnl|extdb|FAM14217-p1-1.1_001596 754252.PFREUD_10700 0.0 1536.5 Propionibacteriales glgX 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2GJ00@201174,4DPSB@85009,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family gnl|extdb|FAM14217-p1-1.1_001599 754252.PFREUD_10670 0.0 1748.0 Propionibacteriales glgP GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1,2.4.1.8 ko:K00688,ko:K00691 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R01555,R02111 RC00049 ko00000,ko00001,ko01000 GH65,GT35 Bacteria 2GIVZ@201174,4DPQE@85009,COG0058@1,COG0058@2 NA|NA|NA G Protein of unknown function (DUF3417) gnl|extdb|FAM14217-p1-1.1_001602 754252.PFREUD_10640 1.5e-266 924.9 Propionibacteriales treS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 ko:K00700,ko:K05343,ko:K16146 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01557,R02108,R02110,R02112,R09945,R11262 RC00002,RC00078,RC01816 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 2GKAP@201174,4DNWM@85009,COG3281@1,COG3281@2 NA|NA|NA G protein probably involved in trehalose biosynthesis gnl|extdb|FAM14217-p1-1.1_001604 754252.PFREUD_10620 4.1e-144 517.3 Propionibacteriales Bacteria 2IFB9@201174,4DWZM@85009,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain gnl|extdb|FAM14217-p1-1.1_001605 754252.PFREUD_10610 0.0 1090.5 Propionibacteriales pgm GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711 Bacteria 2H1PI@201174,4DNWG@85009,COG0033@1,COG0033@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, C-terminal domain gnl|extdb|FAM14217-p1-1.1_001606 754252.PFREUD_10600 1.5e-170 605.5 Propionibacteriales trxA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2GJ7B@201174,4DN3B@85009,COG3118@1,COG3118@2 NA|NA|NA O Tetratricopeptide repeat gnl|extdb|FAM14217-p1-1.1_001607 754252.PFREUD_10590 5.1e-83 313.5 Propionibacteriales mce 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIPR@201174,4DQPV@85009,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gnl|extdb|FAM14217-p1-1.1_001608 754252.PFREUD_10580 3.9e-107 394.0 Propionibacteriales plsC2 Bacteria 2IDC7@201174,4DRMR@85009,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases gnl|extdb|FAM14217-p1-1.1_001609 754252.PFREUD_10570 8.5e-57 228.4 Bacteria ko:K02107 ko00190,map00190 M00159 ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 Bacteria COG3064@1,COG3064@2 NA|NA|NA M translation initiation factor activity gnl|extdb|FAM14217-p1-1.1_001610 754252.PFREUD_10560 4.2e-131 474.2 Propionibacteriales nucS ko:K07503 ko00000,ko01000 Bacteria 2GIYB@201174,4DN0H@85009,COG1637@1,COG1637@2 NA|NA|NA L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures gnl|extdb|FAM14217-p1-1.1_001611 1035308.AQYY01000001_gene2554 5.6e-19 100.1 Bacteria Bacteria 2E3EP@1,32YDP@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001612 754252.PFREUD_10540 2.3e-161 574.7 Propionibacteriales ybfF ko:K01175 ko00000,ko01000 Bacteria 2I5QQ@201174,4DWZK@85009,COG2267@1,COG2267@2 NA|NA|NA I Thioesterase domain gnl|extdb|FAM14217-p1-1.1_001613 754252.PFREUD_10530 1e-110 406.0 Propionibacteriales yvqK 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMHN@201174,4DNZ5@85009,COG2096@1,COG2096@2 NA|NA|NA S Cobalamin adenosyltransferase gnl|extdb|FAM14217-p1-1.1_001615 1122994.AUFR01000001_gene1457 2e-18 99.0 Actinobacteria Bacteria 2E6YX@1,2ISED@201174,331I5@2 NA|NA|NA S Protein of unknown function (DUF2550) gnl|extdb|FAM14217-p1-1.1_001616 754252.PFREUD_10500 2.9e-76 291.2 Bacteria atpC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria COG0355@1,COG0355@2 NA|NA|NA C proton-transporting ATP synthase activity, rotational mechanism gnl|extdb|FAM14217-p1-1.1_001617 754252.PFREUD_10490 2.4e-275 954.1 Propionibacteriales atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 2GIY6@201174,4DMY1@85009,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits gnl|extdb|FAM14217-p1-1.1_001618 754252.PFREUD_10480 1.9e-164 585.1 Propionibacteriales atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 2GJ7Q@201174,4DN4I@85009,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex gnl|extdb|FAM14217-p1-1.1_001619 754252.PFREUD_10470 4.4e-305 1053.1 Propionibacteriales atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2GJRJ@201174,4DNCI@85009,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit gnl|extdb|FAM14217-p1-1.1_001620 754252.PFREUD_10460 3.2e-133 481.1 Actinobacteria atpH ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GMJ5@201174,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation gnl|extdb|FAM14217-p1-1.1_001621 754252.PFREUD_10450 3e-64 251.5 Propionibacteriales atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GJS4@201174,4DQDT@85009,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) gnl|extdb|FAM14217-p1-1.1_001622 754252.PFREUD_10440 2.1e-29 134.4 Actinobacteria atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GQI6@201174,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation gnl|extdb|FAM14217-p1-1.1_001624 754252.PFREUD_10420 3.4e-35 153.7 Bacteria atpI ko:K02116 ko00000,ko00194 3.A.2.1 Bacteria COG5336@1,COG5336@2 NA|NA|NA C function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex gnl|extdb|FAM14217-p1-1.1_001626 754252.PFREUD_10390 1.7e-183 648.7 Propionibacteriales tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2GIT7@201174,4DPQZ@85009,COG0472@1,COG0472@2 NA|NA|NA M Glycosyl transferase family 4 gnl|extdb|FAM14217-p1-1.1_001629 754252.PFREUD_10360 5.1e-193 680.2 Propionibacteriales prfA GO:0008150,GO:0040007 ko:K02835 ko00000,ko03012 Bacteria 2GJWG@201174,4DP4Q@85009,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA gnl|extdb|FAM14217-p1-1.1_001630 754252.PFREUD_10350 2.8e-37 160.6 Bacteria rpmE ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0254@1,COG0254@2 NA|NA|NA J rRNA binding gnl|extdb|FAM14217-p1-1.1_001631 754252.PFREUD_10340 6.4e-271 939.9 Propionibacteriales rho GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 2GIWY@201174,4DN0N@85009,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template gnl|extdb|FAM14217-p1-1.1_001632 754252.PFREUD_10330 1.1e-115 422.5 Bacteria thrH 2.7.1.39,3.1.3.3 ko:K02203 ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230 M00018 R00582,R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria COG0560@1,COG0560@2 NA|NA|NA E Phosphoserine phosphatase gnl|extdb|FAM14217-p1-1.1_001633 754252.PFREUD_10320 4.7e-241 840.1 Propionibacteriales hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 2GIX9@201174,4DPCG@85009,COG0460@1,COG0460@2 NA|NA|NA E Homoserine dehydrogenase gnl|extdb|FAM14217-p1-1.1_001634 754252.PFREUD_10300 4.9e-273 946.4 Propionibacteriales lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKAI@201174,4DPUN@85009,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine gnl|extdb|FAM14217-p1-1.1_001636 754252.PFREUD_10290 9.1e-104 383.3 Propionibacteriales yabI GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0050896,GO:0051301,GO:0071944 3.6.1.27 ko:K03975,ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2GKKC@201174,4DUMN@85009,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein gnl|extdb|FAM14217-p1-1.1_001637 754252.PFREUD_10280 9.4e-86 322.8 Propionibacteriales Bacteria 2GN1J@201174,4DRA3@85009,COG5650@1,COG5650@2 NA|NA|NA S Glycosyltransferase family 87 gnl|extdb|FAM14217-p1-1.1_001638 754252.PFREUD_10280 4.6e-146 523.9 Propionibacteriales Bacteria 2GN1J@201174,4DRA3@85009,COG5650@1,COG5650@2 NA|NA|NA S Glycosyltransferase family 87 gnl|extdb|FAM14217-p1-1.1_001639 754252.PFREUD_10270 7.1e-242 842.8 Propionibacteriales Bacteria 2GN1J@201174,4DRA3@85009,COG5650@1,COG5650@2 NA|NA|NA S Glycosyltransferase family 87 gnl|extdb|FAM14217-p1-1.1_001640 754252.PFREUD_10260 5.9e-113 413.7 Propionibacteriales Bacteria 2GN1J@201174,4DRA3@85009,COG5650@1,COG5650@2 NA|NA|NA S Glycosyltransferase family 87 gnl|extdb|FAM14217-p1-1.1_001641 754252.PFREUD_10260 1.2e-129 469.2 Propionibacteriales Bacteria 2GN1J@201174,4DRA3@85009,COG5650@1,COG5650@2 NA|NA|NA S Glycosyltransferase family 87 gnl|extdb|FAM14217-p1-1.1_001642 754252.PFREUD_10250 0.0 2444.1 Propionibacteriales sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 2GIU6@201174,4DN7Q@85009,COG0508@1,COG0508@2,COG0567@1,COG0567@2 NA|NA|NA C 2-oxoglutarate dehydrogenase gnl|extdb|FAM14217-p1-1.1_001643 754252.PFREUD_10240 2.1e-41 174.5 Propionibacteriales whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K18955 ko00000,ko03000 Bacteria 2DMIE@1,2IQCG@201174,32RSG@2,4DRG4@85009 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA gnl|extdb|FAM14217-p1-1.1_001644 754252.PFREUD_10230 1.6e-285 988.0 Propionibacteriales pdtaS GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K00936 M00839 ko00000,ko00002,ko01000,ko01001,ko02022 Bacteria 2GKMP@201174,4DPYA@85009,COG3920@1,COG3920@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM14217-p1-1.1_001645 754252.PFREUD_10210 1.1e-50 205.7 Bacteria rsrA GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 Bacteria COG5662@1,COG5662@2 NA|NA|NA K AntiSigma factor gnl|extdb|FAM14217-p1-1.1_001647 754252.PFREUD_10190 2.7e-145 521.2 Propionibacteriales Bacteria 2GKY8@201174,4DPFJ@85009,COG2135@1,COG2135@2 NA|NA|NA S Belongs to the SOS response-associated peptidase family gnl|extdb|FAM14217-p1-1.1_001648 754252.PFREUD_10180 2.2e-254 884.4 Propionibacteriales aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJKX@201174,4DNC2@85009,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate gnl|extdb|FAM14217-p1-1.1_001649 754252.PFREUD_10170 1.3e-201 708.8 Propionibacteriales rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 2GJ37@201174,4DNJ3@85009,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit gnl|extdb|FAM14217-p1-1.1_001650 754252.PFREUD_10160 1.7e-153 548.5 Propionibacteriales hisN GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 ko:K05602 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKZZ@201174,4DNRF@85009,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family gnl|extdb|FAM14217-p1-1.1_001651 754252.PFREUD_10150 9.3e-96 357.8 Actinobacteria Bacteria 2GKIT@201174,2Z8AD@2,arCOG08054@1 NA|NA|NA S Carbohydrate-binding domain-containing protein Cthe_2159 gnl|extdb|FAM14217-p1-1.1_001652 754252.PFREUD_10140 2.1e-151 541.6 Propionibacteriales ygiF GO:0003674,GO:0003824,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0046872,GO:0050355 3.6.1.25 ko:K18446 ko00000,ko01000 Bacteria 2II2C@201174,4DV8T@85009,COG3025@1,COG3025@2 NA|NA|NA S VTC domain gnl|extdb|FAM14217-p1-1.1_001654 754252.PFREUD_10120 6.9e-170 603.2 Bacteria XK27_08080 3.1.1.53 ko:K05970 ko00000,ko01000 Bacteria COG4632@1,COG4632@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001655 1132441.KI519454_gene1511 1.1e-79 303.9 Micrococcaceae XK27_08075 Bacteria 1WCNS@1268,2IB2H@201174,COG1216@1,COG1216@2 NA|NA|NA S GtrA-like protein gnl|extdb|FAM14217-p1-1.1_001656 754252.PFREUD_10080 1.3e-221 775.4 Propionibacteriales serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 iYL1228.KPN_03348 Bacteria 2GJGA@201174,4DPHP@85009,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM14217-p1-1.1_001658 754252.PFREUD_10060 4.6e-157 560.5 Actinobacteria ko:K02031 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GIXV@201174,COG0444@1,COG0444@2 NA|NA|NA EP Belongs to the ABC transporter superfamily gnl|extdb|FAM14217-p1-1.1_001659 754252.PFREUD_10050 3.2e-131 474.6 Actinobacteria oppC4 ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GNQ5@201174,COG1173@1,COG1173@2 NA|NA|NA EP ABC-type dipeptide oligopeptide nickel transport systems, permease components gnl|extdb|FAM14217-p1-1.1_001660 754252.PFREUD_10040 5.4e-146 523.9 Propionibacteriales oppB4 ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GK0Z@201174,4DPAR@85009,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_001661 754252.PFREUD_10030 2.6e-288 997.3 Actinobacteria ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ4B@201174,COG0747@1,COG0747@2 NA|NA|NA E Extracellular solute-binding protein, family 5 gnl|extdb|FAM14217-p1-1.1_001663 754252.PFREUD_10010 2.4e-217 761.1 Propionibacteriales bioB 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 iYO844.BSU30200 Bacteria 2GIUE@201174,4DQ0R@85009,COG0502@1,COG0502@2 NA|NA|NA H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism gnl|extdb|FAM14217-p1-1.1_001664 754252.PFREUD_10000 6.3e-50 203.0 Bacteria ko:K06975 ko00000 Bacteria COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase gnl|extdb|FAM14217-p1-1.1_001665 754252.PFREUD_09990 1.7e-245 854.7 Propionibacteriales pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK03@201174,4DNTP@85009,COG0596@1,COG0596@2 NA|NA|NA S Alpha beta hydrolase gnl|extdb|FAM14217-p1-1.1_001667 754252.PFREUD_09970 5.7e-258 896.3 Actinobacteria Bacteria 2GKAT@201174,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 gnl|extdb|FAM14217-p1-1.1_001668 754252.PFREUD_09960 0.0 1883.2 Propionibacteriales GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K09118 ko00000 Bacteria 2GMP3@201174,4DQ0K@85009,COG1615@1,COG1615@2 NA|NA|NA T Uncharacterised protein family (UPF0182) gnl|extdb|FAM14217-p1-1.1_001670 754252.PFREUD_09940 1.8e-187 661.8 Propionibacteriales lon ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 2GJDD@201174,4DQEN@85009,COG3480@1,COG3480@2 NA|NA|NA T Domain present in PSD-95, Dlg, and ZO-1/2. gnl|extdb|FAM14217-p1-1.1_001672 754252.PFREUD_09910 4.4e-99 367.5 Propionibacteriales ko:K07043 ko00000 Bacteria 2GMP6@201174,4DQV0@85009,COG1451@1,COG1451@2 NA|NA|NA S Protein of unknown function DUF45 gnl|extdb|FAM14217-p1-1.1_001673 754252.PFREUD_09900 3.8e-22 110.2 Actinobacteria Bacteria 2E479@1,2GQXY@201174,32Z35@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001676 754252.PFREUD_09860 0.0 2259.6 Propionibacteriales recC 3.1.11.5 ko:K03583 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNVB@201174,4DNIF@85009,COG1330@1,COG1330@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity gnl|extdb|FAM14217-p1-1.1_001677 754252.PFREUD_09850 0.0 2187.5 Propionibacteriales recB GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNKH@201174,4DNNK@85009,COG1074@1,COG1074@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA gnl|extdb|FAM14217-p1-1.1_001679 754252.PFREUD_09830 8.2e-173 612.8 Propionibacteriales nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 1.3.7.1,3.6.1.22 ko:K03426,ko:K20449 ko00760,ko01100,ko01120,ko04146,map00760,map01100,map01120,map04146 R00103,R03004,R03164,R11104 RC00002,RC02422 ko00000,ko00001,ko01000 iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 Bacteria 2GJZY@201174,4DN72@85009,COG2816@1,COG2816@2 NA|NA|NA L NUDIX domain gnl|extdb|FAM14217-p1-1.1_001680 754252.PFREUD_09820 0.0 2187.1 Propionibacteriales uvrD2 3.6.4.12 ko:K03657,ko:K07465 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GM2E@201174,4DP1P@85009,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily gnl|extdb|FAM14217-p1-1.1_001681 754252.PFREUD_09810 0.0 2175.6 Propionibacteriales uvrD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJD0@201174,4DPY8@85009,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily gnl|extdb|FAM14217-p1-1.1_001682 754252.PFREUD_09800 1.2e-31 141.7 Actinobacteria cspC ko:K03704 ko00000,ko03000 Bacteria 2GQRU@201174,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein gnl|extdb|FAM14217-p1-1.1_001683 754252.PFREUD_09790 1.3e-159 568.9 Propionibacteriales prpB10 Bacteria 2GKDM@201174,4DN5I@85009,COG0631@1,COG0631@2 NA|NA|NA T Serine/threonine phosphatases, family 2C, catalytic domain gnl|extdb|FAM14217-p1-1.1_001684 754252.PFREUD_09780 3.2e-33 147.1 Propionibacteriales Bacteria 2E3M2@1,2GQQW@201174,32YJA@2,4DS75@85009 NA|NA|NA S Protein of unknown function (DUF3107) gnl|extdb|FAM14217-p1-1.1_001685 754252.PFREUD_09770 1.2e-137 495.7 Propionibacteriales 1.14.13.149,1.14.13.227,1.14.13.236,4.1.99.5 ko:K02611,ko:K14331,ko:K15760,ko:K18223 ko00360,ko00623,ko00640,ko01100,ko01120,ko01220,map00360,map00623,map00640,map01100,map01120,map01220 M00538 R02550,R03562,R05666,R09838,R10702 RC00269,RC00490,RC02690,RC03249 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXZ@201174,4DMYE@85009,COG3396@1,COG3396@2 NA|NA|NA S tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like gnl|extdb|FAM14217-p1-1.1_001686 754252.PFREUD_09760 8.2e-250 869.4 Propionibacteriales deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4DNNT@85009,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family gnl|extdb|FAM14217-p1-1.1_001687 754252.PFREUD_09750 7.9e-213 746.1 Propionibacteriales trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9A@201174,4DTIS@85009,COG0180@1,COG0180@2 NA|NA|NA J tRNA synthetases class I (W and Y) gnl|extdb|FAM14217-p1-1.1_001688 754252.PFREUD_09740 2.1e-165 588.2 Propionibacteriales PPA1328 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 2GNAP@201174,4DP8Q@85009,COG0613@1,COG0613@2 NA|NA|NA S DNA polymerase alpha chain like domain gnl|extdb|FAM14217-p1-1.1_001689 754252.PFREUD_09730 9.7e-88 329.3 Bacteria Bacteria COG3832@1,COG3832@2 NA|NA|NA J glyoxalase III activity gnl|extdb|FAM14217-p1-1.1_001691 754252.PFREUD_09710 6.5e-90 336.7 Bacteria Bacteria 2DGDU@1,2ZVJF@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001694 754252.PFREUD_09680 9.2e-104 382.9 Propionibacteriales hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 2GMYF@201174,4DQCT@85009,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase gnl|extdb|FAM14217-p1-1.1_001695 754252.PFREUD_09670 8e-151 539.7 Bacteria ctsW ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria COG1040@1,COG1040@2 NA|NA|NA K competence protein gnl|extdb|FAM14217-p1-1.1_001696 754252.PFREUD_09660 1.6e-137 495.4 Propionibacteriales Bacteria 2GJE6@201174,4DP53@85009,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM14217-p1-1.1_001697 754252.PFREUD_09650 2.7e-105 387.9 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07735 ko00000,ko03000 Bacteria 2GNRA@201174,4DR8I@85009,COG1678@1,COG1678@2 NA|NA|NA K Uncharacterized ACR, COG1678 gnl|extdb|FAM14217-p1-1.1_001699 754252.PFREUD_09640 4.8e-114 417.2 Propionibacteriales ko:K09940 ko00000 Bacteria 2GT71@201174,4DSEG@85009,COG3296@1,COG3296@2 NA|NA|NA S Domain of unknown function (DUF4870) gnl|extdb|FAM14217-p1-1.1_001700 754252.PFREUD_09630 5e-84 317.0 Propionibacteriales smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 2GJX1@201174,4DQQA@85009,COG0691@1,COG0691@2 NA|NA|NA O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA gnl|extdb|FAM14217-p1-1.1_001701 754252.PFREUD_09620 0.0 1192.2 Actinobacteria yciQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GNW7@201174,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) gnl|extdb|FAM14217-p1-1.1_001702 754252.PFREUD_09610 2.1e-135 489.2 Propionibacteriales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GXEC@201174,4DPWU@85009,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 gnl|extdb|FAM14217-p1-1.1_001704 754252.PFREUD_09590 4.1e-124 450.7 Propionibacteriales ftsE GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJE1@201174,4DNHN@85009,COG2884@1,COG2884@2 NA|NA|NA D cell division ATP-binding protein FtsE gnl|extdb|FAM14217-p1-1.1_001705 754252.PFREUD_09580 2e-200 704.9 Propionibacteriales prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2GJ0F@201174,4DPCH@85009,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA gnl|extdb|FAM14217-p1-1.1_001706 754252.PFREUD_09570 1e-70 272.7 Propionibacteriales yqeY ko:K09117 ko00000 Bacteria 2IFFJ@201174,4DR27@85009,COG1610@1,COG1610@2 NA|NA|NA S Yqey-like protein gnl|extdb|FAM14217-p1-1.1_001708 754252.PFREUD_09550 8e-151 539.7 Propionibacteriales Bacteria 2GW7W@201174,4DN5P@85009,COG3001@1,COG3001@2 NA|NA|NA G Fructosamine kinase gnl|extdb|FAM14217-p1-1.1_001709 754252.PFREUD_09540 1.2e-252 878.6 Propionibacteriales gabT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GIS9@201174,4DPFZ@85009,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gnl|extdb|FAM14217-p1-1.1_001711 754252.PFREUD_09510 1.1e-251 875.5 Actinobacteria Bacteria 2GNUF@201174,COG0531@1,COG0531@2 NA|NA|NA E amino acid gnl|extdb|FAM14217-p1-1.1_001712 754252.PFREUD_09500 1e-78 299.3 Propionibacteriales hsp20 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2IHVJ@201174,4DQU3@85009,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) gnl|extdb|FAM14217-p1-1.1_001713 754252.PFREUD_09490 0.0 1137.1 Propionibacteriales exsA ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GJWP@201174,4DWN0@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM14217-p1-1.1_001714 754252.PFREUD_09480 1.4e-74 285.4 Propionibacteriales Bacteria 2B57P@1,2I89I@201174,32TPU@2,4DQZ6@85009 NA|NA|NA S Protein of unknown function (DUF3052) gnl|extdb|FAM14217-p1-1.1_001715 754252.PFREUD_09470 0.0 1907.9 Propionibacteriales aceE GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJRE@201174,4DNUA@85009,COG2609@1,COG2609@2 NA|NA|NA C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) gnl|extdb|FAM14217-p1-1.1_001716 754252.PFREUD_09460 1.6e-227 795.0 Actinobacteria tyrB 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2I96J@201174,COG1448@1,COG1448@2 NA|NA|NA E Aminotransferase class I and II gnl|extdb|FAM14217-p1-1.1_001717 754252.PFREUD_09450 1e-213 749.2 Propionibacteriales Bacteria 2GN0S@201174,4DNAE@85009,COG2508@1,COG2508@2 NA|NA|NA QT PucR C-terminal helix-turn-helix domain gnl|extdb|FAM14217-p1-1.1_001718 754252.PFREUD_09440 4.4e-172 610.5 Propionibacteriales fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180,2.3.1.39 ko:K00645,ko:K00648 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082,M00083 R01626,R10707,R11671 RC00004,RC00039,RC02727,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GME0@201174,4DPZC@85009,COG0331@1,COG0331@2 NA|NA|NA I Acyl transferase domain gnl|extdb|FAM14217-p1-1.1_001719 754252.PFREUD_09430 7.6e-167 593.2 Propionibacteriales fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJP8@201174,4DP78@85009,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids gnl|extdb|FAM14217-p1-1.1_001720 754252.PFREUD_09420 1e-35 155.6 Actinobacteria acpP ko:K02078 ko00000,ko00001 Bacteria 2IQ43@201174,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis gnl|extdb|FAM14217-p1-1.1_001721 754252.PFREUD_09410 8.4e-232 809.3 Propionibacteriales fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GIY4@201174,4DN2J@85009,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP gnl|extdb|FAM14217-p1-1.1_001722 754252.PFREUD_09400 1e-92 345.9 Propionibacteriales Bacteria 299E4@1,2GM90@201174,2ZWGX@2,4DQ7U@85009 NA|NA|NA S Protein of unknown function (DUF3145) gnl|extdb|FAM14217-p1-1.1_001723 754252.PFREUD_09390 0.0 1349.0 Propionibacteriales dap2 Bacteria 2GJW4@201174,4DTZJ@85009,COG1506@1,COG1506@2 NA|NA|NA E Dienelactone hydrolase family gnl|extdb|FAM14217-p1-1.1_001724 754252.PFREUD_09380 1.9e-138 498.4 Propionibacteriales yggS 2.5.1.3 ko:K00788,ko:K06997 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMRJ@201174,4DQBA@85009,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis gnl|extdb|FAM14217-p1-1.1_001725 754252.PFREUD_09370 1.6e-169 602.1 Actinobacteria ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2GNKP@201174,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A gnl|extdb|FAM14217-p1-1.1_001726 754252.PFREUD_09360 6.6e-176 623.2 Actinobacteria ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2GNKP@201174,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor, type A gnl|extdb|FAM14217-p1-1.1_001727 754252.PFREUD_09350 1e-184 652.5 Propionibacteriales Bacteria 2GKSJ@201174,4DPV4@85009,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 gnl|extdb|FAM14217-p1-1.1_001728 754252.PFREUD_09340 2.3e-188 664.8 Propionibacteriales ko:K03924 ko00000,ko01000 Bacteria 2GK07@201174,4DNJJ@85009,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) gnl|extdb|FAM14217-p1-1.1_001729 754252.PFREUD_09330 3e-117 428.3 Propionibacteriales Bacteria 2BYTB@1,2IIS4@201174,33S2I@2,4DSUF@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001730 754252.PFREUD_09320 1.5e-155 555.4 Propionibacteriales Bacteria 2GP42@201174,4DR0A@85009,COG0561@1,COG0561@2 NA|NA|NA J hydrolases of the HAD superfamily gnl|extdb|FAM14217-p1-1.1_001731 754252.PFREUD_09310 5.1e-257 893.3 Propionibacteriales dldH5 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJJK@201174,4DNK2@85009,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM14217-p1-1.1_001732 754252.PFREUD_09300 2.9e-127 461.1 Bacteria Bacteria COG5423@1,COG5423@2 NA|NA|NA M Predicted metal-binding protein (DUF2284) gnl|extdb|FAM14217-p1-1.1_001736 754252.PFREUD_09260 4.7e-145 520.4 Propionibacteriales sdhB 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJPS@201174,4DPU6@85009,COG0479@1,COG0479@2 NA|NA|NA C Succinate dehydrogenase fumarate reductase gnl|extdb|FAM14217-p1-1.1_001738 754252.PFREUD_09240 2.8e-137 494.6 Propionibacteriales sdhC_1 ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 28HIR@1,2I860@201174,30UAY@2,4DWJ7@85009 NA|NA|NA C succinate dehydrogenase gnl|extdb|FAM14217-p1-1.1_001739 754252.PFREUD_09230 1.4e-136 492.3 Actinobacteria 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2GNMT@201174,COG1051@1,COG1051@2 NA|NA|NA F NUDIX hydrolase gnl|extdb|FAM14217-p1-1.1_001740 754252.PFREUD_09220 9.3e-186 656.0 Actinobacteria nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS12020 Bacteria 2GM59@201174,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate gnl|extdb|FAM14217-p1-1.1_001741 754252.PFREUD_09210 2.3e-311 1074.7 Propionibacteriales nadB GO:0008150,GO:0040007 1.3.5.4,1.4.3.16 ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1595 Bacteria 2I2IJ@201174,4DN9N@85009,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate gnl|extdb|FAM14217-p1-1.1_001742 754252.PFREUD_09200 2.6e-166 591.3 Propionibacteriales nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2IP@201174,4DNUU@85009,COG0157@1,COG0157@2 NA|NA|NA H Belongs to the NadC ModD family gnl|extdb|FAM14217-p1-1.1_001743 754252.PFREUD_09190 3.2e-280 970.3 Propionibacteriales glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria 2GIT3@201174,4DPNB@85009,COG0423@1,COG0423@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family gnl|extdb|FAM14217-p1-1.1_001744 754252.PFREUD_09180 1.2e-174 619.0 Propionibacteriales scbA ko:K09815 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 Bacteria 2GM1K@201174,4DNM9@85009,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic gnl|extdb|FAM14217-p1-1.1_001745 754252.PFREUD_09170 9.2e-144 516.2 Propionibacteriales ko:K09817 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 Bacteria 2GP3A@201174,4DPIC@85009,COG1121@1,COG1121@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_001746 754252.PFREUD_09160 1.7e-158 565.5 Propionibacteriales ko:K09816 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 Bacteria 2GJ7H@201174,4DPI0@85009,COG1108@1,COG1108@2 NA|NA|NA P ABC 3 transport family gnl|extdb|FAM14217-p1-1.1_001748 1122994.AUFR01000004_gene658 2.6e-22 112.5 Bacteria Bacteria COG0582@1,COG0582@2 NA|NA|NA L DNA integration gnl|extdb|FAM14217-p1-1.1_001749 754252.PFREUD_09130 7.2e-264 916.0 Propionibacteriales pduP 1.2.1.87 ko:K13922 ko00640,map00640 R09097 RC00004,RC00184 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2291,iECED1_1282.ECED1_3458 Bacteria 2GJI2@201174,4DQ06@85009,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family gnl|extdb|FAM14217-p1-1.1_001750 754252.PFREUD_09120 1.5e-192 678.7 Actinobacteria MMAB 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMHN@201174,COG2096@1,COG2096@2,COG3193@1,COG3193@2 NA|NA|NA S adenosyltransferase gnl|extdb|FAM14217-p1-1.1_001751 754252.PFREUD_09110 1.5e-40 171.8 Bacteria eutN ko:K04028 ko00000 Bacteria COG4576@1,COG4576@2 NA|NA|NA CQ ethanolamine utilization protein EutN carboxysome structural protein Ccml gnl|extdb|FAM14217-p1-1.1_001752 754252.PFREUD_09100 3e-143 514.6 Bacteria spoVFB ko:K06411 ko00000 iYO844.BSU16740 Bacteria COG0452@1,COG0452@2 NA|NA|NA H phosphopantothenoylcysteine decarboxylase activity gnl|extdb|FAM14217-p1-1.1_001753 754252.PFREUD_09090 5.9e-152 543.5 Actinobacteria eutJ ko:K04024 ko00000 Bacteria 2II7P@201174,COG4820@1,COG4820@2 NA|NA|NA E ethanolamine utilization protein gnl|extdb|FAM14217-p1-1.1_001754 754252.PFREUD_09080 2.4e-38 164.5 Bacteria pduJ ko:K04027 ko00000 Bacteria COG4577@1,COG4577@2 NA|NA|NA CQ ethanolamine catabolic process gnl|extdb|FAM14217-p1-1.1_001755 754252.PFREUD_09070 1.5e-77 295.8 Bacteria pduK Bacteria COG4577@1,COG4577@2 NA|NA|NA CQ ethanolamine catabolic process gnl|extdb|FAM14217-p1-1.1_001756 754252.PFREUD_09060 7e-56 223.0 Bacteria Bacteria 2DQX8@1,33960@2 NA|NA|NA S Dehydratase medium subunit gnl|extdb|FAM14217-p1-1.1_001757 754252.PFREUD_09050 0.0 1143.3 Actinobacteria pduG ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 2GNUI@201174,COG0849@1,COG0849@2 NA|NA|NA D Diol dehydratase reactivase ATPase-like domain gnl|extdb|FAM14217-p1-1.1_001758 754252.PFREUD_09040 8e-91 339.7 Actinobacteria pduE 4.2.1.28,4.2.1.30 ko:K06122,ko:K13920 ko00561,ko00640,map00561,map00640 R01047,R02376 RC00429,RC00707 ko00000,ko00001,ko01000 Bacteria 2IN09@201174,COG4910@1,COG4910@2 NA|NA|NA Q Dehydratase small subunit gnl|extdb|FAM14217-p1-1.1_001759 754252.PFREUD_09030 5.5e-116 423.7 Actinobacteria pduD 4.2.1.28,4.2.1.30 ko:K06121,ko:K13919 ko00561,ko00640,map00561,map00640 R01047,R02376 RC00429,RC00707 ko00000,ko00001,ko01000 Bacteria 2HPSF@201174,COG4909@1,COG4909@2 NA|NA|NA Q Dehydratase medium subunit gnl|extdb|FAM14217-p1-1.1_001760 754252.PFREUD_09020 0.0 1092.4 Actinobacteria dhaB 4.2.1.28,4.2.1.30 ko:K01699,ko:K06120 ko00561,ko00640,map00561,map00640 R01047,R02376 RC00429,RC00707 ko00000,ko00001,ko01000 Bacteria 2GP0B@201174,COG4909@1,COG4909@2 NA|NA|NA Q Dehydratase large subunit gnl|extdb|FAM14217-p1-1.1_001761 754252.PFREUD_09010 2.6e-141 508.1 Bacteria pduB Bacteria COG4816@1,COG4816@2 NA|NA|NA E ethanolamine catabolic process gnl|extdb|FAM14217-p1-1.1_001762 754252.PFREUD_09000 8.1e-42 176.0 Propionibacteriales pduA Bacteria 2IM0X@201174,4DVB3@85009,COG4577@1,COG4577@2 NA|NA|NA CQ BMC gnl|extdb|FAM14217-p1-1.1_001763 754252.PFREUD_08990 1.9e-53 214.9 Actinobacteria pduU ko:K04031 ko00000 Bacteria 2H7SK@201174,COG4810@1,COG4810@2 NA|NA|NA E BMC gnl|extdb|FAM14217-p1-1.1_001764 754252.PFREUD_08980 3.3e-71 274.2 Actinobacteria eutP ko:K04029 ko00000 Bacteria 2HC70@201174,COG4917@1,COG4917@2 NA|NA|NA E Ethanolamine utilisation - propanediol utilisation gnl|extdb|FAM14217-p1-1.1_001765 754252.PFREUD_08140 3.3e-103 380.9 Propionibacteriales Bacteria 2ICWK@201174,4DRNE@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM14217-p1-1.1_001766 754252.PFREUD_08150 1.1e-102 379.8 Propionibacteriales Bacteria 2GVE1@201174,4DRJW@85009,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM14217-p1-1.1_001768 754252.PFREUD_08970 3.1e-199 701.0 Propionibacteriales pduQ ko:K13921 ko00640,map00640 R02377 RC00087 ko00000,ko00001 Bacteria 2I2FD@201174,4DTE9@85009,COG1454@1,COG1454@2 NA|NA|NA C Iron-containing alcohol dehydrogenase gnl|extdb|FAM14217-p1-1.1_001769 754252.PFREUD_08960 3.2e-216 757.7 Bacteria pocR Bacteria COG4936@1,COG4936@2 NA|NA|NA KT Sensory domain found in PocR gnl|extdb|FAM14217-p1-1.1_001770 754252.PFREUD_08950 6.2e-142 510.0 Propionibacteriales recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GK81@201174,4DP6A@85009,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination gnl|extdb|FAM14217-p1-1.1_001771 754252.PFREUD_08940 1.5e-146 525.4 Propionibacteriales uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68,2.5.1.86,2.5.1.88 ko:K00806,ko:K12503,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R08528,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2GIXF@201174,4DPW4@85009,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids gnl|extdb|FAM14217-p1-1.1_001772 754252.PFREUD_08930 1.1e-62 245.7 Actinobacteria yeaO Bacteria 2IQC0@201174,COG3189@1,COG3189@2 NA|NA|NA K Protein of unknown function, DUF488 gnl|extdb|FAM14217-p1-1.1_001773 754252.PFREUD_08920 0.0 1204.5 Propionibacteriales leuA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GISX@201174,4DMZU@85009,COG0119@1,COG0119@2 NA|NA|NA E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) gnl|extdb|FAM14217-p1-1.1_001774 754252.PFREUD_08910 5.8e-288 996.1 Propionibacteriales Bacteria 2GJVW@201174,4DN27@85009,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family gnl|extdb|FAM14217-p1-1.1_001776 754252.PFREUD_08870 7.9e-174 616.3 Propionibacteriales era GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043021,GO:0043024,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070181,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:1901363 ko:K03595 ko00000,ko03009,ko03029 Bacteria 2GJJE@201174,4DNEH@85009,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism gnl|extdb|FAM14217-p1-1.1_001777 754252.PFREUD_08860 6.9e-229 799.7 Propionibacteriales corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GIWR@201174,4DNND@85009,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain gnl|extdb|FAM14217-p1-1.1_001778 754252.PFREUD_08850 1.5e-82 312.0 Propionibacteriales ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2GMUF@201174,4DQJA@85009,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA gnl|extdb|FAM14217-p1-1.1_001779 754252.PFREUD_08840 3.4e-183 647.5 Propionibacteriales phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 2GK0W@201174,4DPI2@85009,COG1702@1,COG1702@2 NA|NA|NA T PhoH-like protein gnl|extdb|FAM14217-p1-1.1_001780 754252.PFREUD_08830 4.7e-247 860.1 Propionibacteriales ko:K03761,ko:K03762 ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 Bacteria 2GIYR@201174,4DPBG@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter gnl|extdb|FAM14217-p1-1.1_001784 754252.PFREUD_08790 6.9e-250 869.4 Actinobacteria tgt 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 2GMWY@201174,COG0343@1,COG0343@2 NA|NA|NA J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) gnl|extdb|FAM14217-p1-1.1_001785 754252.PFREUD_08780 2.6e-263 914.1 Actinobacteria 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 R00191 RC00296 ko00000,ko00001,ko01000 Bacteria 2IDNH@201174,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase gnl|extdb|FAM14217-p1-1.1_001786 754252.PFREUD_08770 1.5e-127 462.2 Propionibacteriales rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 1.13.12.16,2.1.1.193 ko:K00459,ko:K09761 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000,ko03009 Bacteria 2GTKX@201174,4DQEM@85009,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit gnl|extdb|FAM14217-p1-1.1_001787 754252.PFREUD_08760 8.7e-202 709.5 Propionibacteriales dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03686 ko00000,ko03029,ko03110 Bacteria 2GK69@201174,4DPD2@85009,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins gnl|extdb|FAM14217-p1-1.1_001788 754252.PFREUD_08750 2.1e-180 638.3 Propionibacteriales hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 2GKF5@201174,4DP2Y@85009,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons gnl|extdb|FAM14217-p1-1.1_001789 754252.PFREUD_08740 1.2e-148 532.3 Propionibacteriales suhB2 3.1.3.25,3.1.3.7 ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 M00131 R00188,R00508,R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GP74@201174,4DQB7@85009,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family gnl|extdb|FAM14217-p1-1.1_001790 754252.PFREUD_08730 3.8e-170 604.0 Propionibacteriales trpH GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0097657,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 2GIZ5@201174,4DN6Z@85009,COG0613@1,COG0613@2 NA|NA|NA S Protein of unknown function (DUF3097) gnl|extdb|FAM14217-p1-1.1_001791 754252.PFREUD_08720 3.3e-233 813.9 Propionibacteriales hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 2GJXX@201174,4DN32@85009,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound gnl|extdb|FAM14217-p1-1.1_001792 754252.PFREUD_08710 0.0 1191.8 Propionibacteriales lepA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 2GJAB@201174,4DNM0@85009,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner gnl|extdb|FAM14217-p1-1.1_001793 754252.PFREUD_08690 2.7e-106 391.3 Actinobacteria Bacteria 2DQ2A@1,2I1WX@201174,334FV@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001794 754252.PFREUD_08680 2e-34 151.4 Propionibacteriales rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ73@201174,4DS53@85009,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA gnl|extdb|FAM14217-p1-1.1_001796 754252.PFREUD_08660 2.6e-179 634.8 Propionibacteriales holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GNMZ@201174,4DN5C@85009,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III, delta subunit gnl|extdb|FAM14217-p1-1.1_001797 754252.PFREUD_08650 0.0 1471.1 Propionibacteriales comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2GJGR@201174,4DP9N@85009,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein gnl|extdb|FAM14217-p1-1.1_001798 754252.PFREUD_08640 3.2e-162 577.8 Propionibacteriales comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2IQDC@201174,4DRFZ@85009,COG1555@1,COG1555@2 NA|NA|NA L Helix-hairpin-helix motif gnl|extdb|FAM14217-p1-1.1_001799 754252.PFREUD_08630 0.0 1119.0 Propionibacteriales malS GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 R00214 RC00105 ko00000,ko00001,ko01000 Bacteria 2GJAJ@201174,4DTGZ@85009,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme, NAD binding domain gnl|extdb|FAM14217-p1-1.1_001800 754252.PFREUD_08620 5.4e-250 869.8 Propionibacteriales pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0T@201174,4DMZJ@85009,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily gnl|extdb|FAM14217-p1-1.1_001801 754252.PFREUD_08610 0.0 1724.9 Propionibacteriales leuS 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJI1@201174,4DNGN@85009,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family gnl|extdb|FAM14217-p1-1.1_001802 1203605.HMPREF1531_00010 8.5e-25 121.3 Bacteria Bacteria 2E68X@1,330WZ@2 NA|NA|NA S Domain of unknown function (DUF4192) gnl|extdb|FAM14217-p1-1.1_001805 754252.PFREUD_08570 4.8e-176 623.6 Actinobacteria Bacteria 2GNH5@201174,COG0451@1,COG0451@2 NA|NA|NA GM NAD-dependent epimerase dehydratase gnl|extdb|FAM14217-p1-1.1_001806 754252.PFREUD_08560 3e-75 287.7 Actinobacteria Bacteria 2EKIG@1,2INGR@201174,33E8D@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001807 754252.PFREUD_08550 1.2e-111 409.1 Propionibacteriales gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.73,3.1.3.85 ko:K02226,ko:K22306 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJYU@201174,4DRFR@85009,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family gnl|extdb|FAM14217-p1-1.1_001808 754252.PFREUD_08540 8.4e-66 256.1 Propionibacteriales rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2IKZ3@201174,4DR96@85009,COG0799@1,COG0799@2 NA|NA|NA S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation gnl|extdb|FAM14217-p1-1.1_001809 754252.PFREUD_08530 4.3e-146 523.9 Propionibacteriales nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2GMFZ@201174,4DNX3@85009,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) gnl|extdb|FAM14217-p1-1.1_001810 754252.PFREUD_08510 8.9e-226 789.3 Propionibacteriales proA GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0293,iNJ661.Rv2427c,iYO844.BSU13130 Bacteria 2GISA@201174,4DNEG@85009,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate gnl|extdb|FAM14217-p1-1.1_001811 1032480.MLP_36030 1.8e-15 89.7 Bacteria Bacteria 2DYDK@1,34999@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001813 754252.PFREUD_08480 1.1e-305 1055.0 Propionibacteriales obg GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 ko:K03979 ko00000,ko01000,ko03009 Bacteria 2GISB@201174,4DNZK@85009,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control gnl|extdb|FAM14217-p1-1.1_001814 754252.PFREUD_08460 7.5e-42 176.0 Propionibacteriales rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQDI@201174,4DRNG@85009,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family gnl|extdb|FAM14217-p1-1.1_001815 754252.PFREUD_08450 3.3e-49 200.7 Propionibacteriales rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ9A@201174,4DRJ6@85009,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 gnl|extdb|FAM14217-p1-1.1_001816 754252.PFREUD_08440 1.3e-288 999.2 Propionibacteriales rne GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2GMM5@201174,4DPJ7@85009,COG1530@1,COG1530@2 NA|NA|NA J Ribonuclease E/G family gnl|extdb|FAM14217-p1-1.1_001818 754252.PFREUD_08410 8.7e-78 296.2 Propionibacteriales Bacteria 2I08G@201174,4DW84@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM14217-p1-1.1_001819 754252.PFREUD_08400 7.6e-225 786.2 Propionibacteriales terC ko:K05794 ko00000 Bacteria 2GIWU@201174,4DNCF@85009,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family gnl|extdb|FAM14217-p1-1.1_001821 754252.PFREUD_08380 0.0 1322.8 Propionibacteriales Bacteria 2GJY1@201174,4DNWJ@85009,COG1032@1,COG1032@2 NA|NA|NA C Elongator protein 3, MiaB family, Radical SAM gnl|extdb|FAM14217-p1-1.1_001822 754252.PFREUD_08370 6.2e-241 839.7 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity gnl|extdb|FAM14217-p1-1.1_001823 754252.PFREUD_08360 7.2e-83 313.2 Propionibacteriales ndk 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 2IFBU@201174,4DQR5@85009,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate gnl|extdb|FAM14217-p1-1.1_001824 754252.PFREUD_08350 1.2e-277 961.8 Propionibacteriales folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJP2@201174,4DNMV@85009,COG0285@1,COG0285@2 NA|NA|NA H Mur ligase middle domain gnl|extdb|FAM14217-p1-1.1_001825 754252.PFREUD_08340 1.5e-106 392.1 Actinobacteria ko:K15977 ko00000 Bacteria 2IQEY@201174,COG2259@1,COG2259@2 NA|NA|NA O DoxX family gnl|extdb|FAM14217-p1-1.1_001826 754252.PFREUD_08330 2.6e-109 401.7 Actinobacteria pknE_1 Bacteria 2GKH8@201174,COG1651@1,COG1651@2 NA|NA|NA O DSBA oxidoreductase gnl|extdb|FAM14217-p1-1.1_001827 754252.PFREUD_08320 5.2e-110 404.1 Actinobacteria pknE_1 Bacteria 2GKH8@201174,COG1651@1,COG1651@2 NA|NA|NA O DSBA oxidoreductase gnl|extdb|FAM14217-p1-1.1_001828 754252.PFREUD_08310 0.0 1795.8 Propionibacteriales valS 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK8H@201174,4DNR2@85009,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner gnl|extdb|FAM14217-p1-1.1_001829 754252.PFREUD_08300 3.5e-140 504.2 Actinobacteria ko:K07025 ko00000 Bacteria 2GNSS@201174,COG1011@1,COG1011@2 NA|NA|NA S hydrolase gnl|extdb|FAM14217-p1-1.1_001830 754252.PFREUD_08290 5.1e-204 716.8 Propionibacteriales pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iJN678.pfkA Bacteria 2GK6W@201174,4DPJ3@85009,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis gnl|extdb|FAM14217-p1-1.1_001831 754252.PFREUD_08280 5.1e-281 973.0 Actinobacteria thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRY@201174,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase gnl|extdb|FAM14217-p1-1.1_001832 754252.PFREUD_08270 6.6e-53 213.0 Actinobacteria Bacteria 2EKUG@1,2GTFS@201174,33EI5@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001833 754252.PFREUD_08260 2.5e-239 834.3 Propionibacteriales clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2GJXQ@201174,4DP0T@85009,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP gnl|extdb|FAM14217-p1-1.1_001834 754252.PFREUD_08250 4.3e-121 440.7 Propionibacteriales clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKNK@201174,4DNRI@85009,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins gnl|extdb|FAM14217-p1-1.1_001836 754252.PFREUD_08230 3.1e-223 780.8 Actinobacteria tqsA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944 ko:K11744 ko00000 Bacteria 2GM01@201174,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter gnl|extdb|FAM14217-p1-1.1_001837 754252.PFREUD_08220 2.8e-208 731.1 Propionibacteriales tqsA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944 ko:K11744 ko00000 Bacteria 2GM01@201174,4DT6M@85009,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter gnl|extdb|FAM14217-p1-1.1_001838 754252.PFREUD_08210 4.3e-249 867.1 Propionibacteriales tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K03545 ko00000 Bacteria 2GJIG@201174,4DP8U@85009,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase gnl|extdb|FAM14217-p1-1.1_001845 754252.PFREUD_08150 1.1e-102 379.8 Propionibacteriales Bacteria 2GVE1@201174,4DRJW@85009,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM14217-p1-1.1_001846 754252.PFREUD_08140 3.3e-103 380.9 Propionibacteriales Bacteria 2ICWK@201174,4DRNE@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM14217-p1-1.1_001847 754252.PFREUD_08130 0.0 1453.7 Propionibacteriales ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJUY@201174,4DNKM@85009,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA gnl|extdb|FAM14217-p1-1.1_001848 754252.PFREUD_08120 9.9e-146 522.7 Propionibacteriales Bacteria 2CNM1@1,2GKWT@201174,32SHB@2,4DR39@85009 NA|NA|NA S Nuclease-related domain gnl|extdb|FAM14217-p1-1.1_001850 754252.PFREUD_08100 0.0 1725.7 Propionibacteriales pepN 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ4@201174,4DNEA@85009,COG0308@1,COG0308@2 NA|NA|NA E ERAP1-like C-terminal domain gnl|extdb|FAM14217-p1-1.1_001851 754252.PFREUD_08090 1.8e-281 974.5 Propionibacteriales gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 2GJ2J@201174,4DQ33@85009,COG0362@1,COG0362@2 NA|NA|NA G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnl|extdb|FAM14217-p1-1.1_001852 754252.PFREUD_08080 1.4e-150 538.9 Actinobacteria thiD 2.7.1.35,2.7.1.49,2.7.4.7 ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 M00127 R00174,R01909,R02493,R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKZM@201174,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase gnl|extdb|FAM14217-p1-1.1_001853 754252.PFREUD_08070 2.4e-169 601.3 Propionibacteriales ko:K07107 ko00000,ko01000 Bacteria 2IFAK@201174,4DRTF@85009,COG0824@1,COG0824@2 NA|NA|NA S Acyl-ACP thioesterase gnl|extdb|FAM14217-p1-1.1_001854 754252.PFREUD_08060 0.0 1276.5 Propionibacteriales fadD11_1 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4DNTY@85009,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme gnl|extdb|FAM14217-p1-1.1_001855 754252.PFREUD_08050 3.3e-77 294.3 Propionibacteriales Bacteria 2GP6A@201174,4DR7Q@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM14217-p1-1.1_001857 754252.PFREUD_08030 0.0 1364.0 Actinobacteria dcp 3.4.15.5,3.4.24.70 ko:K01284,ko:K01414 ko00000,ko01000,ko01002 Bacteria 2GM2Z@201174,COG0339@1,COG0339@2 NA|NA|NA E PFAM peptidase M3A and M3B, thimet oligopeptidase F gnl|extdb|FAM14217-p1-1.1_001858 754252.PFREUD_08010 3.9e-275 953.4 Actinobacteria Bacteria 2IA73@201174,COG1085@1,COG1085@2 NA|NA|NA C uridylyltransferase gnl|extdb|FAM14217-p1-1.1_001859 754252.PFREUD_08000 2.2e-258 897.9 Propionibacteriales ptsI GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033554,GO:0033558,GO:0034983,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047324,GO:0050896,GO:0051716,GO:0071704,GO:0098732,GO:0140096,GO:1901564 2.7.1.121,2.7.1.202,2.7.3.9 ko:K02768,ko:K05881,ko:K08483,ko:K11183,ko:K11189 ko00051,ko00561,ko01100,ko01120,ko02060,map00051,map00561,map01100,map01120,map02060 M00273 R01012,R03232 RC00015,RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 iECs_1301.ECs1703,iSF_1195.SF1201,iS_1188.S1285,iUTI89_1310.UTI89_C1391,iZ_1308.Z1969 Bacteria 2GIZZ@201174,4DNRM@85009,COG1080@1,COG1080@2,COG1925@1,COG1925@2,COG3412@1,COG3412@2 NA|NA|NA G PTS system fructose IIA component gnl|extdb|FAM14217-p1-1.1_001860 754252.PFREUD_07990 5e-108 397.1 Propionibacteriales dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 R01012 RC00015,RC00017 ko00000,ko00001,ko01000 iECUMN_1333.ECUMN_1495 Bacteria 2HEQ9@201174,4DQSR@85009,COG1461@1,COG1461@2 NA|NA|NA S Dak2 gnl|extdb|FAM14217-p1-1.1_001861 754252.PFREUD_07980 4.7e-185 653.7 Propionibacteriales dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 2.7.1.121,2.7.1.209,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K20901 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059,R11460 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 Bacteria 2GJV9@201174,4DN06@85009,COG2376@1,COG2376@2 NA|NA|NA G Dihydroxyacetone kinase gnl|extdb|FAM14217-p1-1.1_001862 754252.PFREUD_07970 0.0 1133.6 Propionibacteriales yjjK GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 2GKBQ@201174,4DNB9@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM14217-p1-1.1_001863 754252.PFREUD_07960 7.3e-63 246.9 Propionibacteriales ssb2 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GQIQ@201174,4DS96@85009,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein gnl|extdb|FAM14217-p1-1.1_001864 754252.PFREUD_07950 1e-127 462.6 Propionibacteriales 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 2IG1G@201174,4DVST@85009,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase gnl|extdb|FAM14217-p1-1.1_001865 754252.PFREUD_07940 5.9e-302 1042.7 Propionibacteriales PPA1638 ko:K06883 ko00000 Bacteria 2GM68@201174,4DPRU@85009,COG0699@1,COG0699@2 NA|NA|NA S 50S ribosome-binding GTPase gnl|extdb|FAM14217-p1-1.1_001866 754252.PFREUD_07930 0.0 1102.0 Propionibacteriales ko:K06883 ko00000 Bacteria 2GJX9@201174,4DPB6@85009,COG0699@1,COG0699@2 NA|NA|NA S ABC transporter gnl|extdb|FAM14217-p1-1.1_001867 754252.PFREUD_07920 1.9e-262 911.4 Propionibacteriales Bacteria 2GKR5@201174,4DQ3Y@85009,COG2339@1,COG2339@2 NA|NA|NA S Protease prsW family gnl|extdb|FAM14217-p1-1.1_001869 754252.PFREUD_07900 2.1e-222 778.1 Propionibacteriales Bacteria 2H0CW@201174,4DN0M@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_001873 754252.PFREUD_07870 8.7e-87 326.2 Actinobacteria relA_2 2.7.4.1,2.7.6.5,3.1.7.2 ko:K00937,ko:K01139 ko00190,ko00230,ko03018,map00190,map00230,map03018 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2IHTX@201174,COG0317@1,COG0317@2 NA|NA|NA KT HD domain gnl|extdb|FAM14217-p1-1.1_001874 754252.PFREUD_07860 0.0 1542.3 Propionibacteriales uvrA2 Bacteria 2GJUV@201174,4DN67@85009,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter gnl|extdb|FAM14217-p1-1.1_001876 754252.PFREUD_07840 3e-256 890.6 Propionibacteriales murE 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2I2TV@201174,4DU2N@85009,COG0769@1,COG0769@2 NA|NA|NA M Domain of unknown function (DUF1727) gnl|extdb|FAM14217-p1-1.1_001877 754252.PFREUD_07830 1.7e-145 521.9 Propionibacteriales cobQ ko:K07009 ko00000 iSB619.SA_RS09800 Bacteria 2GKPV@201174,4DUT1@85009,COG3442@1,COG3442@2 NA|NA|NA S CobB/CobQ-like glutamine amidotransferase domain gnl|extdb|FAM14217-p1-1.1_001879 754252.PFREUD_07810 1.4e-75 288.9 Propionibacteriales groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IHRC@201174,4DR8F@85009,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter gnl|extdb|FAM14217-p1-1.1_001880 1120954.ATXE01000003_gene587 2.4e-07 61.6 Bacteria Bacteria 296K5@1,2ZTVJ@2 NA|NA|NA S Protein of unknown function (DUF3618) gnl|extdb|FAM14217-p1-1.1_001881 754252.PFREUD_07790 4.9e-87 327.0 Propionibacteriales bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 ko00000,ko01000 iPC815.YPO3064 Bacteria 2IHZ6@201174,4DQGR@85009,COG1225@1,COG1225@2 NA|NA|NA O Redoxin gnl|extdb|FAM14217-p1-1.1_001883 754252.PFREUD_07770 4.3e-129 467.2 Propionibacteriales araD 4.1.2.17,5.1.3.4 ko:K01628,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R02262,R05850 RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNI6@201174,4DNAZ@85009,COG0235@1,COG0235@2 NA|NA|NA G Class II Aldolase and Adducin N-terminal domain gnl|extdb|FAM14217-p1-1.1_001884 754252.PFREUD_07760 1.1e-141 509.2 Propionibacteriales cobK 1.3.1.106,1.3.1.54,1.3.1.76,2.1.1.131,2.1.1.132,3.7.1.12,4.99.1.4 ko:K00595,ko:K02304,ko:K05895,ko:K05934,ko:K13541 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947,R05149,R05150,R05180,R05809,R05812,R07772 RC00003,RC01012,RC01034,RC01279,RC01280,RC01293,RC01545,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMYZ@201174,4DPKR@85009,COG2099@1,COG2099@2 NA|NA|NA H reductase gnl|extdb|FAM14217-p1-1.1_001885 754252.PFREUD_07750 4.5e-111 407.1 Propionibacteriales cobL 2.1.1.132 ko:K00595 ko00860,ko01100,map00860,map01100 R05149 RC00003,RC01279 ko00000,ko00001,ko01000 Bacteria 2GM8G@201174,4DNG6@85009,COG2242@1,COG2242@2 NA|NA|NA H Precorrin-6y C5,15-methyltransferase gnl|extdb|FAM14217-p1-1.1_001886 754252.PFREUD_07730 8.3e-114 416.4 Propionibacteriales cobH 1.7.7.1,2.1.1.130,2.1.1.151,5.4.99.60,5.4.99.61 ko:K00366,ko:K03394,ko:K06042 ko00860,ko00910,ko01100,ko01120,map00860,map00910,map01100,map01120 M00531 R00790,R03948,R05177,R05808,R05814 RC00003,RC00176,RC01035,RC01292,RC01662,RC01980 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK0B@201174,4DPQK@85009,COG2082@1,COG2082@2 NA|NA|NA H Precorrin-8X methylmutase gnl|extdb|FAM14217-p1-1.1_001887 754252.PFREUD_07720 3.2e-234 817.4 Actinobacteria cbiD 2.1.1.195 ko:K02006,ko:K02188 ko00860,ko01100,ko02010,map00860,map01100,map02010 M00245,M00246 R07773 RC00003,RC02051 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 2GM41@201174,COG1903@1,COG1903@2 NA|NA|NA H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A gnl|extdb|FAM14217-p1-1.1_001890 754252.PFREUD_07690 1.6e-177 628.6 Propionibacteriales cobM 1.3.1.76,2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,4.99.1.4 ko:K02304,ko:K05936,ko:K13541 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947,R05180,R05181,R05809,R05810,R07772 RC00003,RC01012,RC01034,RC01293,RC01294,RC01545,RC02049,RC02097,RC03471 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ97@201174,4DPG8@85009,COG2875@1,COG2875@2 NA|NA|NA H Belongs to the precorrin methyltransferase family gnl|extdb|FAM14217-p1-1.1_001892 754252.PFREUD_07660 0.0 1261.1 Propionibacteriales mutA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944 2.7.7.7,5.4.99.2,5.4.99.63 ko:K01847,ko:K03763,ko:K14447 ko00230,ko00240,ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko03030,ko03430,ko03440,map00230,map00240,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map03030,map03430,map03440 M00260,M00373,M00376,M00741 R00375,R00376,R00377,R00378,R00833,R09292 RC00395,RC02795,RC02835 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GNBQ@201174,4DNT9@85009,COG1884@1,COG1884@2 NA|NA|NA I Methylmalonyl-CoA mutase gnl|extdb|FAM14217-p1-1.1_001893 754252.PFREUD_07650 0.0 1442.6 Propionibacteriales mutB 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM65@201174,4DWYX@85009,COG1884@1,COG1884@2,COG2185@1,COG2185@2 NA|NA|NA I Methylmalonyl-CoA mutase gnl|extdb|FAM14217-p1-1.1_001894 754252.PFREUD_07640 1.9e-186 658.3 Propionibacteriales argK GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 ko:K07588 ko00000,ko01000 Bacteria 2GME8@201174,4DP5N@85009,COG1703@1,COG1703@2 NA|NA|NA E ArgK protein gnl|extdb|FAM14217-p1-1.1_001895 754252.PFREUD_07630 1e-265 922.2 Propionibacteriales dinB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.7 ko:K02346,ko:K03502 ko00000,ko01000,ko03400 Bacteria 2GKBI@201174,4DN0X@85009,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII gnl|extdb|FAM14217-p1-1.1_001897 754252.PFREUD_07610 2e-162 578.2 Propionibacteriales thyA 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKY0@201174,4DPMT@85009,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis gnl|extdb|FAM14217-p1-1.1_001898 754252.PFREUD_07600 2.8e-148 531.2 Propionibacteriales rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2GM2B@201174,4DQ0I@85009,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions gnl|extdb|FAM14217-p1-1.1_001899 754252.PFREUD_07590 2.4e-136 491.5 Propionibacteriales rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 ko:K00989,ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJFI@201174,4DN7G@85009,COG0689@1,COG0689@2 NA|NA|NA J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates gnl|extdb|FAM14217-p1-1.1_001900 754252.PFREUD_07580 8.1e-151 539.7 Propionibacteriales murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0042802,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 2GN4I@201174,4DP8J@85009,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis gnl|extdb|FAM14217-p1-1.1_001901 754252.PFREUD_07570 1.9e-112 411.8 Propionibacteriales Bacteria 2E4AX@1,2GW4T@201174,32Z6K@2,4DQGY@85009 NA|NA|NA S Domain of unknown function (DUF2017) gnl|extdb|FAM14217-p1-1.1_001902 754252.PFREUD_07560 3.8e-50 203.8 Propionibacteriales clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 ko:K06891 ko00000 Bacteria 2IQ3Z@201174,4DRQZ@85009,COG2127@1,COG2127@2 NA|NA|NA S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation gnl|extdb|FAM14217-p1-1.1_001903 754252.PFREUD_07550 1.4e-253 881.7 Propionibacteriales pncB 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 2GJAT@201174,4DN3A@85009,COG1488@1,COG1488@2 NA|NA|NA H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP gnl|extdb|FAM14217-p1-1.1_001904 754252.PFREUD_07540 6.8e-192 676.4 Propionibacteriales menB GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK5G@201174,4DNED@85009,COG0447@1,COG0447@2 NA|NA|NA H Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily gnl|extdb|FAM14217-p1-1.1_001905 754252.PFREUD_07530 7.7e-230 802.7 Propionibacteriales menE GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN9C@201174,4DP67@85009,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme gnl|extdb|FAM14217-p1-1.1_001906 754252.PFREUD_07520 1.2e-249 868.6 Propionibacteriales menF 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKE8@201174,4DPGF@85009,COG1169@1,COG1169@2 NA|NA|NA HQ Isochorismate synthase gnl|extdb|FAM14217-p1-1.1_001908 754252.PFREUD_07500 0.0 1663.3 Actinobacteria uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GNMW@201174,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate gnl|extdb|FAM14217-p1-1.1_001909 754252.PFREUD_07490 6.9e-311 1072.4 Propionibacteriales menD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05085 Bacteria 2GMEB@201174,4DPUU@85009,COG1165@1,COG1165@2 NA|NA|NA H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) gnl|extdb|FAM14217-p1-1.1_001910 754252.PFREUD_07480 5.9e-180 636.7 Propionibacteriales menC GO:0008150,GO:0040007 4.2.1.113,5.1.1.20,5.1.1.3 ko:K01776,ko:K02549,ko:K19802 ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110 M00116 R00260,R04031,R10938 RC00302,RC01053,RC03309 ko00000,ko00001,ko00002,ko01000,ko01011 iNJ661.Rv0553,iSB619.SA_RS09080 Bacteria 2GJJR@201174,4DNKN@85009,COG4948@1,COG4948@2 NA|NA|NA M Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) gnl|extdb|FAM14217-p1-1.1_001911 754252.PFREUD_07470 0.0 1510.7 Propionibacteriales malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 ko:K00700,ko:K00705,ko:K02438,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R02110,R02111,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13,GH77 iJN678.malQ Bacteria 2GM5Z@201174,4DPPR@85009,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase gnl|extdb|FAM14217-p1-1.1_001912 754252.PFREUD_07460 9.2e-139 500.0 Bacteria Bacteria COG1714@1,COG1714@2 NA|NA|NA S RDD family gnl|extdb|FAM14217-p1-1.1_001913 754252.PFREUD_07450 3.6e-263 913.7 Propionibacteriales Bacteria 2GKY2@201174,4DQFD@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_001914 754252.PFREUD_07440 1.9e-45 188.0 Bacteria Bacteria 2CAFG@1,32RRB@2 NA|NA|NA S Protein of unknown function (DUF3039) gnl|extdb|FAM14217-p1-1.1_001915 754252.PFREUD_07430 4.9e-169 600.5 Propionibacteriales cat Bacteria 2GKSG@201174,4DPUX@85009,COG0053@1,COG0053@2 NA|NA|NA P Cation efflux family gnl|extdb|FAM14217-p1-1.1_001916 754252.PFREUD_07420 1.8e-176 625.2 Propionibacteriales 5.3.1.8,5.3.1.9 ko:K15916 ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R01819,R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMG0@201174,4DMZS@85009,COG1737@1,COG1737@2 NA|NA|NA K Bacterial phospho-glucose isomerase C-terminal SIS domain gnl|extdb|FAM14217-p1-1.1_001918 754252.PFREUD_07400 2.3e-153 548.1 Actinobacteria cof 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2HZD0@201174,COG0561@1,COG0561@2 NA|NA|NA T HAD hydrolase, family IIB gnl|extdb|FAM14217-p1-1.1_001919 1122994.AUFR01000021_gene225 2.1e-25 122.9 Propionibacteriales Bacteria 2C7XW@1,2IQ5R@201174,32RR4@2,4DRSS@85009 NA|NA|NA S Protein of unknown function (DUF3499) gnl|extdb|FAM14217-p1-1.1_001920 754252.PFREUD_07380 2.4e-43 181.0 Propionibacteriales MA20_43655 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2GR5W@201174,4DS4T@85009,COG3824@1,COG3824@2 NA|NA|NA S Zincin-like metallopeptidase gnl|extdb|FAM14217-p1-1.1_001922 754252.PFREUD_07360 0.0 2124.4 Propionibacteriales Bacteria 2GIUN@201174,4DN93@85009,COG1216@1,COG1216@2 NA|NA|NA S PFAM Glycosyl transferase family 2 gnl|extdb|FAM14217-p1-1.1_001923 754252.PFREUD_07350 4.7e-44 183.3 Propionibacteriales whiB2 ko:K18955 ko00000,ko03000 Bacteria 2CC1Y@1,2IQ4Q@201174,32RUK@2,4DRN7@85009 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA gnl|extdb|FAM14217-p1-1.1_001924 754252.PFREUD_07340 3.8e-156 557.8 Bacteria Bacteria 2956M@1,2ZSJ3@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001925 754252.PFREUD_07330 3.5e-202 710.7 Propionibacteriales manC 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRM@201174,4DPTJ@85009,COG0836@1,COG0836@2 NA|NA|NA M Nucleotidyl transferase gnl|extdb|FAM14217-p1-1.1_001926 754252.PFREUD_07320 2.5e-229 801.2 Propionibacteriales lytR2 Bacteria 2GJJJ@201174,4DPY2@85009,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain gnl|extdb|FAM14217-p1-1.1_001928 754252.PFREUD_07300 2.1e-224 784.6 Propionibacteriales purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 2GJCU@201174,4DPHF@85009,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) gnl|extdb|FAM14217-p1-1.1_001929 754252.PFREUD_07290 1e-133 482.6 Propionibacteriales Bacteria 2GZK5@201174,4DR4C@85009,COG3340@1,COG3340@2 NA|NA|NA E Peptidase family S51 gnl|extdb|FAM14217-p1-1.1_001930 754252.PFREUD_07280 1.2e-103 382.5 Actinobacteria Bacteria 2GX8K@201174,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_001931 754252.PFREUD_07260 3.6e-85 320.9 Bacteria ko:K08981 ko00000 Bacteria COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain gnl|extdb|FAM14217-p1-1.1_001932 754252.PFREUD_07250 7.1e-152 543.1 Propionibacteriales birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03524 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GN8Q@201174,4DQT5@85009,COG0340@1,COG0340@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family gnl|extdb|FAM14217-p1-1.1_001933 754252.PFREUD_07240 2.5e-101 374.8 Bacteria ko:K21961 ko00000,ko03000 Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_001934 754252.PFREUD_07230 4.9e-102 377.1 Propionibacteriales Bacteria 2GNYV@201174,4DRAY@85009,COG1510@1,COG1510@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_001935 754252.PFREUD_07220 1.8e-95 355.1 Actinobacteria Bacteria 2DWTW@1,2GPSK@201174,341UU@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001936 754252.PFREUD_07210 1.8e-170 605.1 Propionibacteriales yjjC ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKEH@201174,4DPD1@85009,COG1131@1,COG1131@2 NA|NA|NA V PFAM ABC transporter related gnl|extdb|FAM14217-p1-1.1_001937 754252.PFREUD_07200 4.8e-191 673.7 Propionibacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMSI@201174,4DPHI@85009,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide gnl|extdb|FAM14217-p1-1.1_001938 1122622.ATWJ01000001_gene2519 1.9e-25 122.5 Intrasporangiaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMSI@201174,4FFJC@85021,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide gnl|extdb|FAM14217-p1-1.1_001939 754252.PFREUD_07180 6.6e-251 872.8 Bacteria yjjP Bacteria COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA H response to peptide gnl|extdb|FAM14217-p1-1.1_001940 754252.PFREUD_07170 9.7e-302 1042.0 Propionibacteriales pccB GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494 2.1.3.1,2.1.3.15,6.4.1.3 ko:K01966,ko:K17489 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R00353,R01859 RC00040,RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRU@201174,4DNBQ@85009,COG4799@1,COG4799@2 NA|NA|NA I Carboxyl transferase domain gnl|extdb|FAM14217-p1-1.1_001942 754252.PFREUD_07150 1.4e-133 482.3 Propionibacteriales maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2GNI0@201174,4DQJD@85009,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein gnl|extdb|FAM14217-p1-1.1_001943 754252.PFREUD_07140 2.6e-91 341.3 Actinobacteria 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2IKKB@201174,COG1051@1,COG1051@2 NA|NA|NA F Nudix hydrolase gnl|extdb|FAM14217-p1-1.1_001944 765123.HMPREF9621_02000 2.4e-14 85.5 Bacteria Bacteria COG2235@1,COG2235@2 NA|NA|NA E arginine gnl|extdb|FAM14217-p1-1.1_001945 754252.PFREUD_07110 2.1e-159 568.2 Propionibacteriales nei1 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K05522,ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKUI@201174,4DN81@85009,COG0266@1,COG0266@2 NA|NA|NA L Belongs to the FPG family gnl|extdb|FAM14217-p1-1.1_001946 754252.PFREUD_07100 0.0 1165.6 Propionibacteriales accA 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIZP@201174,4DMZN@85009,COG4770@1,COG4770@2 NA|NA|NA I Biotin carboxylase C-terminal domain gnl|extdb|FAM14217-p1-1.1_001948 754252.PFREUD_07080 4.9e-182 643.7 Bacteria 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria COG0167@1,COG0167@2 NA|NA|NA F dihydroorotate dehydrogenase activity gnl|extdb|FAM14217-p1-1.1_001949 754252.PFREUD_07070 0.0 2417.1 Propionibacteriales nifJ GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 iJN678.nifJ,iLF82_1304.LF82_2789,iNRG857_1313.NRG857_06920 Bacteria 2I995@201174,4DVUV@85009,COG0674@1,COG0674@2,COG1013@1,COG1013@2,COG1014@1,COG1014@2,COG1143@1,COG1143@2 NA|NA|NA C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin gnl|extdb|FAM14217-p1-1.1_001950 754252.PFREUD_07060 0.0 1159.4 Actinobacteria yciQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GNW7@201174,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) gnl|extdb|FAM14217-p1-1.1_001951 754252.PFREUD_07050 5.6e-197 693.3 Actinobacteria Bacteria 2GNFX@201174,COG1063@1,COG1063@2 NA|NA|NA E Dehydrogenase gnl|extdb|FAM14217-p1-1.1_001952 754252.PFREUD_07030 1.1e-115 422.5 Bacteria Bacteria COG0454@1,COG0454@2 NA|NA|NA K -acetyltransferase gnl|extdb|FAM14217-p1-1.1_001954 754252.PFREUD_07010 4.6e-70 270.4 Propionibacteriales pcaC 4.1.1.44 ko:K01607,ko:K04756 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 2HFD1@201174,4DVHT@85009,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family gnl|extdb|FAM14217-p1-1.1_001955 754252.PFREUD_07000 2e-61 241.5 Actinobacteria Bacteria 2IFX0@201174,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_001956 754252.PFREUD_06990 5.8e-74 283.5 Actinobacteria Bacteria 2A77J@1,2GVFK@201174,30W3R@2 NA|NA|NA S Protein of unknown function (DUF3290) gnl|extdb|FAM14217-p1-1.1_001958 754252.PFREUD_06970 7.2e-180 636.3 Propionibacteriales cobB ko:K12410 ko00000,ko01000 Bacteria 2GJI3@201174,4DPHU@85009,COG0846@1,COG0846@2 NA|NA|NA K Sir2 family gnl|extdb|FAM14217-p1-1.1_001959 754252.PFREUD_06960 0.0 1165.2 Propionibacteriales metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK4S@201174,4DNQ0@85009,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation gnl|extdb|FAM14217-p1-1.1_001960 754252.PFREUD_06950 6.2e-171 606.7 Propionibacteriales hibch 3.1.2.4,4.2.1.17 ko:K01692,ko:K05605 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00013,M00032,M00087 R03026,R03045,R03158,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05064,R05595,R06411,R06412,R06942,R08093 RC00004,RC00014,RC00137,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMET@201174,4DR5H@85009,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase gnl|extdb|FAM14217-p1-1.1_001961 754252.PFREUD_06940 2.6e-94 351.3 Propionibacteriales Bacteria 2I096@201174,4DWBJ@85009,COG1514@1,COG1514@2 NA|NA|NA J 2'-5' RNA ligase superfamily gnl|extdb|FAM14217-p1-1.1_001962 754252.PFREUD_06930 5.9e-183 646.7 Propionibacteriales rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GK53@201174,4DR5Z@85009,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids gnl|extdb|FAM14217-p1-1.1_001963 754252.PFREUD_06920 4.1e-187 660.6 Actinobacteria ko:K07335 ko00000 Bacteria 2GMFS@201174,COG1744@1,COG1744@2 NA|NA|NA S basic membrane gnl|extdb|FAM14217-p1-1.1_001965 754252.PFREUD_06900 1.2e-277 961.8 Propionibacteriales ytfL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 2GKN5@201174,4DPDV@85009,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain gnl|extdb|FAM14217-p1-1.1_001967 1035308.AQYY01000001_gene1840 1.4e-23 115.5 Bacteria Bacteria 2E45J@1,32Z1K@2 NA|NA|NA S branched-chain amino acid gnl|extdb|FAM14217-p1-1.1_001968 754252.PFREUD_06870 4.5e-238 830.1 Actinobacteria icd GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GM3D@201174,COG0538@1,COG0538@2 NA|NA|NA C Belongs to the isocitrate and isopropylmalate dehydrogenases family gnl|extdb|FAM14217-p1-1.1_001969 754252.PFREUD_06860 1.5e-183 648.7 Propionibacteriales mdh GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJHS@201174,4DN1I@85009,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate gnl|extdb|FAM14217-p1-1.1_001970 754252.PFREUD_06850 1.3e-51 208.8 Bacteria Bacteria 2DRQP@1,33CNM@2 NA|NA|NA S Protein of unknown function (DUF3017) gnl|extdb|FAM14217-p1-1.1_001971 754252.PFREUD_06840 4.5e-160 570.5 Propionibacteriales folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZS@201174,4DNC5@85009,COG0190@1,COG0190@2 NA|NA|NA H Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate gnl|extdb|FAM14217-p1-1.1_001972 754252.PFREUD_06830 6.9e-292 1009.2 Propionibacteriales purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS04230,iJN678.purH Bacteria 2GJWU@201174,4DP1R@85009,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH gnl|extdb|FAM14217-p1-1.1_001973 754252.PFREUD_06820 8.8e-108 396.7 Propionibacteriales purN GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564 2.1.2.2,2.1.2.3,3.5.4.10 ko:K00602,ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04325,R04326,R04560 RC00026,RC00197,RC00263,RC00456,RC01128 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2H8QB@201174,4DPAW@85009,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate gnl|extdb|FAM14217-p1-1.1_001974 754252.PFREUD_06800 0.0 1617.4 Propionibacteriales pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GISS@201174,4DP2M@85009,COG0210@1,COG0210@2 NA|NA|NA L UvrD-like helicase C-terminal domain gnl|extdb|FAM14217-p1-1.1_001975 754252.PFREUD_06790 1.7e-245 854.7 Propionibacteriales cls-1 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_3078 Bacteria 2GM0P@201174,4DP3Y@85009,COG1502@1,COG1502@2 NA|NA|NA I Phospholipase D. Active site motifs. gnl|extdb|FAM14217-p1-1.1_001976 754252.PFREUD_06780 2.2e-134 485.0 Actinobacteria yclP 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 2I2KS@201174,COG4604@1,COG4604@2 NA|NA|NA P ABC transporter gnl|extdb|FAM14217-p1-1.1_001977 754252.PFREUD_06770 7.1e-176 623.2 Actinobacteria fatC ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GN2I@201174,COG4605@1,COG4605@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM14217-p1-1.1_001979 754252.PFREUD_06750 2e-183 648.3 Actinobacteria fatB ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GK6Q@201174,COG4607@1,COG4607@2 NA|NA|NA P ABC-type enterochelin transport system periplasmic component gnl|extdb|FAM14217-p1-1.1_001980 754252.PFREUD_06740 9.4e-26 122.5 Bacteria MA20_40075 Bacteria COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein gnl|extdb|FAM14217-p1-1.1_001981 754252.PFREUD_06730 5.2e-122 443.7 Propionibacteriales degU ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2GIVA@201174,4DQ1R@85009,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon gnl|extdb|FAM14217-p1-1.1_001982 754252.PFREUD_06720 5.9e-219 766.5 Propionibacteriales tcsS3 Bacteria 2GJ4J@201174,4DNII@85009,COG1983@1,COG1983@2,COG4585@1,COG4585@2 NA|NA|NA T PspC domain gnl|extdb|FAM14217-p1-1.1_001983 754252.PFREUD_06710 5.1e-59 233.4 Actinobacteria pspC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0019222,GO:0044464,GO:0048518,GO:0050789,GO:0060255,GO:0065007,GO:0071944 ko:K03973 ko00000,ko02048,ko03000 Bacteria 2IRZU@201174,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain gnl|extdb|FAM14217-p1-1.1_001985 754252.PFREUD_06690 3.9e-175 620.5 Actinobacteria Bacteria 2GXBT@201174,COG3878@1,COG3878@2 NA|NA|NA S Domain of unknown function (DUF1963) gnl|extdb|FAM14217-p1-1.1_001986 754252.PFREUD_06680 4.4e-299 1033.1 Propionibacteriales guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 2GM09@201174,4DPFU@85009,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP gnl|extdb|FAM14217-p1-1.1_001987 754252.PFREUD_06670 4.4e-178 630.6 Propionibacteriales yjfF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 iECW_1372.ECW_m4592,iEKO11_1354.EKO11_4080,iWFL_1372.ECW_m4592 Bacteria 2GJDW@201174,4DQ7E@85009,COG1172@1,COG1172@2 NA|NA|NA G Branched-chain amino acid transport system / permease component gnl|extdb|FAM14217-p1-1.1_001988 754252.PFREUD_06660 8.4e-100 370.5 Actinobacteria ytfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 iAPECO1_1312.APECO1_2162,iECH74115_1262.ECH74115_5749,iECOK1_1307.ECOK1_4745,iECSF_1327.ECSF_4119,iLF82_1304.LF82_3716,iUTI89_1310.UTI89_C4834,ic_1306.c5327 Bacteria 2HB45@201174,COG1172@1,COG1172@2 NA|NA|NA G Belongs to the binding-protein-dependent transport system permease family gnl|extdb|FAM14217-p1-1.1_001990 754252.PFREUD_06630 4.6e-169 600.5 Propionibacteriales ko:K02058 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 2GJ0Z@201174,4DQJY@85009,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein domain gnl|extdb|FAM14217-p1-1.1_001991 754252.PFREUD_06620 8.6e-190 669.5 Propionibacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4DQ8P@85009,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM14217-p1-1.1_001992 754252.PFREUD_06610 5.9e-296 1022.7 Propionibacteriales araA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 R01761 RC00516 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060 Bacteria 2GJNB@201174,4DPD0@85009,COG2160@1,COG2160@2 NA|NA|NA G Catalyzes the conversion of L-arabinose to L-ribulose gnl|extdb|FAM14217-p1-1.1_001995 754252.PFREUD_06560 8.8e-162 576.2 Actinobacteria cysK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIXE@201174,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family gnl|extdb|FAM14217-p1-1.1_001996 754252.PFREUD_06550 1.4e-85 322.4 Propionibacteriales cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0840 Bacteria 2IHW5@201174,4DSPI@85009,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) gnl|extdb|FAM14217-p1-1.1_001997 1089453.GOSPT_088_00130 7.7e-17 94.7 Gordoniaceae Bacteria 2B35U@1,2HX5K@201174,31VTR@2,4GDYQ@85026 NA|NA|NA S N-acetylmuramoyl-L-alanine amidase gnl|extdb|FAM14217-p1-1.1_001999 521393.JH806632_gene597 4.5e-10 73.2 Actinobacteria Bacteria 2IBDZ@201174,4D3UV@85005,COG1520@1,COG1520@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane gnl|extdb|FAM14217-p1-1.1_002002 754252.PFREUD_06490 1e-204 719.2 Propionibacteriales guaB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKVS@201174,4DN1G@85009,COG0516@1,COG0516@2 NA|NA|NA F IMP dehydrogenase / GMP reductase domain gnl|extdb|FAM14217-p1-1.1_002003 754252.PFREUD_06480 3.8e-287 993.4 Propionibacteriales guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GITZ@201174,4DN68@85009,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth gnl|extdb|FAM14217-p1-1.1_002004 754252.PFREUD_06470 8e-288 995.7 Propionibacteriales groL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2GKC9@201174,4DNCJ@85009,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions gnl|extdb|FAM14217-p1-1.1_002005 754252.PFREUD_06460 4.8e-45 186.8 Propionibacteriales groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IKTH@201174,4DR0X@85009,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter gnl|extdb|FAM14217-p1-1.1_002007 754252.PFREUD_06440 8.4e-123 446.4 Propionibacteriales opuBB ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2H9I7@201174,4DTU3@85009,COG1174@1,COG1174@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_002008 754252.PFREUD_06430 4e-240 837.0 Actinobacteria proV ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GJHI@201174,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter gnl|extdb|FAM14217-p1-1.1_002009 754252.PFREUD_06420 7.6e-104 383.3 Actinobacteria ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 2GMQT@201174,COG1174@1,COG1174@2 NA|NA|NA E ABC transporter permease gnl|extdb|FAM14217-p1-1.1_002010 754252.PFREUD_06410 2.7e-260 904.0 Propionibacteriales Bacteria 2GK97@201174,4DPMI@85009,COG2265@1,COG2265@2 NA|NA|NA J COG0500 SAM-dependent methyltransferases gnl|extdb|FAM14217-p1-1.1_002011 754252.PFREUD_06400 2.5e-231 807.7 Propionibacteriales tetV Bacteria 2GJPT@201174,4DP19@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_002012 754252.PFREUD_06390 5.6e-91 340.1 Actinobacteria mutT 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2INEI@201174,COG1051@1,COG1051@2 NA|NA|NA F NTP pyrophosphohydrolases including oxidative damage repair enzymes gnl|extdb|FAM14217-p1-1.1_002013 754252.PFREUD_06380 2.7e-282 977.2 Propionibacteriales pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 2HCVR@201174,4DWUZ@85009,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family gnl|extdb|FAM14217-p1-1.1_002014 754252.PFREUD_06370 0.0 1216.4 Propionibacteriales bluB GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,2.1.1.107,2.4.2.21 ko:K00768,ko:K02303,ko:K04719 ko00740,ko00860,ko01100,ko01110,ko01120,map00740,map00860,map01100,map01110,map01120 M00121,M00122 R03194,R04148,R09083 RC00003,RC00033,RC00063,RC00435,RC00871,RC02413 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ16@201174,4DWZJ@85009,COG0778@1,COG0778@2,COG2038@1,COG2038@2 NA|NA|NA CH Phosphoribosyltransferase gnl|extdb|FAM14217-p1-1.1_002015 754252.PFREUD_06360 3.2e-195 687.6 Propionibacteriales tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GJ98@201174,4DP6P@85009,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction gnl|extdb|FAM14217-p1-1.1_002016 754252.PFREUD_06350 2.6e-94 351.3 Propionibacteriales rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128,2.3.1.234 ko:K01409,ko:K03789,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03009,ko03016 Bacteria 2HZJQ@201174,4DRZ3@85009,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM14217-p1-1.1_002017 754252.PFREUD_06340 2.9e-125 454.5 Propionibacteriales yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 2GMTM@201174,4DQ98@85009,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family gnl|extdb|FAM14217-p1-1.1_002020 754252.PFREUD_06310 1.7e-215 755.0 Propionibacteriales mgtA GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K12583 ko00000,ko01000,ko01003 GT4 Bacteria 2GIZG@201174,4DNSP@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM14217-p1-1.1_002021 754252.PFREUD_06300 2.1e-263 914.4 Propionibacteriales nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2GJHB@201174,4DN6W@85009,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration gnl|extdb|FAM14217-p1-1.1_002022 754252.PFREUD_06290 5.2e-62 243.8 Propionibacteriales acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQF6@201174,4DRCQ@85009,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein gnl|extdb|FAM14217-p1-1.1_002023 754252.PFREUD_06280 0.0 1216.1 Propionibacteriales glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 2GKH0@201174,4DNBT@85009,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gnl|extdb|FAM14217-p1-1.1_002024 754252.PFREUD_06270 1.3e-201 708.8 Propionibacteriales coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 2GIRR@201174,4DPFH@85009,COG1072@1,COG1072@2 NA|NA|NA H pantothenate kinase activity gnl|extdb|FAM14217-p1-1.1_002025 754252.PFREUD_06260 2e-247 861.3 Propionibacteriales glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iAF987.Gmet_1886,iLJ478.TM0184,iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 2GN87@201174,4DNFP@85009,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gnl|extdb|FAM14217-p1-1.1_002026 754252.PFREUD_06250 6.4e-85 320.1 Propionibacteriales rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GNDY@201174,4DQN0@85009,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family gnl|extdb|FAM14217-p1-1.1_002027 754252.PFREUD_06240 6.9e-80 303.1 Propionibacteriales rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFG1@201174,4DQET@85009,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly gnl|extdb|FAM14217-p1-1.1_002028 754252.PFREUD_06230 0.0 1389.0 Propionibacteriales fusA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 ko:K02355 ko00000,ko03012,ko03029 Bacteria 2GKRU@201174,4DNXI@85009,COG0480@1,COG0480@2 NA|NA|NA J Elongation factor G, domain IV gnl|extdb|FAM14217-p1-1.1_002031 754252.PFREUD_06200 1.9e-166 591.7 Propionibacteriales truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2GJ6C@201174,4DPSE@85009,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs gnl|extdb|FAM14217-p1-1.1_002033 1120954.ATXE01000003_gene432 6e-25 120.9 Bacteria Bacteria 2E775@1,331R0@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002034 754252.PFREUD_06160 1.2e-197 695.7 Propionibacteriales ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GKHK@201174,4DPHW@85009,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein gnl|extdb|FAM14217-p1-1.1_002035 754252.PFREUD_06150 1.3e-301 1041.6 Propionibacteriales ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2I2Y2@201174,4DP2H@85009,COG3845@1,COG3845@2 NA|NA|NA S AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM14217-p1-1.1_002037 754252.PFREUD_06130 2.9e-146 524.6 Actinobacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2BWH2@1,2GMNW@201174,2Z89R@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002038 754252.PFREUD_06130 2.3e-121 441.8 Actinobacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2BWH2@1,2GMNW@201174,2Z89R@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002040 754252.PFREUD_06110 2.4e-115 421.4 Propionibacteriales sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 2GJV8@201174,4DQ3N@85009,COG0605@1,COG0605@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems gnl|extdb|FAM14217-p1-1.1_002041 754252.PFREUD_06100 2.8e-191 674.5 Propionibacteriales rpfB GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 ko:K21687,ko:K21688 ko00000 GH23 Bacteria 2H4RU@201174,4DMZZ@85009,COG3583@1,COG3583@2 NA|NA|NA M G5 gnl|extdb|FAM14217-p1-1.1_002042 754252.PFREUD_06090 5e-215 753.4 Propionibacteriales ko:K14335 ko00000,ko01000,ko01003 GT4 Bacteria 2GNYW@201174,4DPGM@85009,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 gnl|extdb|FAM14217-p1-1.1_002043 754252.PFREUD_06080 3.6e-60 238.0 Propionibacteriales rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHV2@201174,4DQBP@85009,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 gnl|extdb|FAM14217-p1-1.1_002044 754252.PFREUD_06070 1.1e-186 659.1 Propionibacteriales rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJJ5@201174,4DNW6@85009,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM14217-p1-1.1_002045 754252.PFREUD_06060 1.9e-109 401.7 Propionibacteriales rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GIRX@201174,4DP75@85009,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit gnl|extdb|FAM14217-p1-1.1_002046 754252.PFREUD_06050 6.1e-67 260.0 Propionibacteriales rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFFC@201174,4DQ7M@85009,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome gnl|extdb|FAM14217-p1-1.1_002047 754252.PFREUD_06040 5.7e-59 233.4 Propionibacteriales rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHPN@201174,4DQUI@85009,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits gnl|extdb|FAM14217-p1-1.1_002048 754252.PFREUD_06030 3.1e-13 79.7 Bacteria rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family gnl|extdb|FAM14217-p1-1.1_002049 754252.PFREUD_06020 1.1e-33 148.7 Propionibacteriales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 2IQ4B@201174,4DRMG@85009,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex gnl|extdb|FAM14217-p1-1.1_002050 754252.PFREUD_06010 1.4e-46 191.8 Propionibacteriales ko:K09780 ko00000 Bacteria 2GQTW@201174,4DSNY@85009,COG2350@1,COG2350@2 NA|NA|NA S YCII-related domain gnl|extdb|FAM14217-p1-1.1_002051 1120954.ATXE01000003_gene392 5e-10 70.9 Propionibacteriales Bacteria 2HP3B@201174,4DSH5@85009,COG4758@1,COG4758@2 NA|NA|NA S Domain of unknown function (DUF1707) gnl|extdb|FAM14217-p1-1.1_002052 754252.PFREUD_05990 3.1e-161 574.3 Propionibacteriales map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2GKKB@201174,4DNQ9@85009,COG0024@1,COG0024@2 NA|NA|NA J Methionine aminopeptidase gnl|extdb|FAM14217-p1-1.1_002053 754252.PFREUD_05980 4.9e-102 377.1 Propionibacteriales adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJ7T@201174,4DP2T@85009,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism gnl|extdb|FAM14217-p1-1.1_002054 754252.PFREUD_05970 1.8e-240 838.2 Propionibacteriales secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 2GJ26@201174,4DN3Y@85009,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently gnl|extdb|FAM14217-p1-1.1_002056 754252.PFREUD_05950 5.1e-176 623.6 Actinobacteria dppC ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ9E@201174,COG1173@1,COG1173@2 NA|NA|NA EP PFAM binding-protein-dependent transport systems inner membrane component gnl|extdb|FAM14217-p1-1.1_002057 754252.PFREUD_05940 0.0 1382.5 Propionibacteriales oppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,4DWGB@85009,COG1123@1,COG4172@2 NA|NA|NA P Oligopeptide/dipeptide transporter, C-terminal region gnl|extdb|FAM14217-p1-1.1_002058 754252.PFREUD_05930 2.4e-311 1074.3 Propionibacteriales oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ9N@201174,4DUB4@85009,COG0747@1,COG0747@2 NA|NA|NA E COG0747 ABC-type dipeptide transport system, periplasmic component gnl|extdb|FAM14217-p1-1.1_002059 754252.PFREUD_05920 3.7e-237 827.0 Propionibacteriales Bacteria 2GKCU@201174,4DNNU@85009,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase gnl|extdb|FAM14217-p1-1.1_002060 754252.PFREUD_05910 1.4e-110 405.6 Propionibacteriales ssuE 1.5.1.38 ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 R05706,R07210,R10206 RC00126,RC01779,RC02556 ko00000,ko00001,ko01000 Bacteria 2IHWU@201174,4DQNQ@85009,COG0431@1,COG0431@2 NA|NA|NA S FMN reductase gnl|extdb|FAM14217-p1-1.1_002061 754252.PFREUD_05900 1.5e-74 285.4 Propionibacteriales rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2II6M@201174,4DQND@85009,COG0200@1,COG0200@2 NA|NA|NA J binds to the 23S rRNA gnl|extdb|FAM14217-p1-1.1_002062 754252.PFREUD_05890 2.2e-24 117.5 Bacteria rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG1841@1,COG1841@2 NA|NA|NA J maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) gnl|extdb|FAM14217-p1-1.1_002063 754252.PFREUD_05880 6.2e-79 300.4 Propionibacteriales rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW8@201174,4DNXT@85009,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body gnl|extdb|FAM14217-p1-1.1_002064 754252.PFREUD_05870 1.4e-60 238.8 Propionibacteriales rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKTX@201174,4DR5B@85009,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance gnl|extdb|FAM14217-p1-1.1_002065 754252.PFREUD_05860 1.4e-98 365.5 Propionibacteriales rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK35@201174,4DNFZ@85009,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center gnl|extdb|FAM14217-p1-1.1_002066 754252.PFREUD_05850 6.6e-69 266.5 Propionibacteriales rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHQZ@201174,4DQQ1@85009,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit gnl|extdb|FAM14217-p1-1.1_002067 754252.PFREUD_05840 7.4e-28 129.0 Bacteria rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site gnl|extdb|FAM14217-p1-1.1_002069 754252.PFREUD_05820 1.6e-58 231.9 Propionibacteriales rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKP2@201174,4DRJP@85009,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit gnl|extdb|FAM14217-p1-1.1_002070 754252.PFREUD_05810 9.3e-62 242.7 Propionibacteriales rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHNX@201174,4DQTB@85009,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome gnl|extdb|FAM14217-p1-1.1_002071 754252.PFREUD_05800 1.8e-41 174.9 Propionibacteriales rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ68@201174,4DRI1@85009,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA gnl|extdb|FAM14217-p1-1.1_002072 754252.PFREUD_05790 1.2e-36 158.7 Propionibacteriales rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ6V@201174,4DRUK@85009,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family gnl|extdb|FAM14217-p1-1.1_002073 754252.PFREUD_05780 1.3e-75 288.9 Propionibacteriales rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFEI@201174,4DQ7S@85009,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs gnl|extdb|FAM14217-p1-1.1_002074 754252.PFREUD_05770 4.4e-96 357.8 Propionibacteriales rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GKF1@201174,4DNUB@85009,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation gnl|extdb|FAM14217-p1-1.1_002075 754252.PFREUD_05760 3.5e-77 294.3 Propionibacteriales rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IM3J@201174,4DQNW@85009,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome gnl|extdb|FAM14217-p1-1.1_002076 754252.PFREUD_05750 7.5e-48 196.1 Propionibacteriales rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKMS@201174,4DR2Q@85009,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA gnl|extdb|FAM14217-p1-1.1_002077 754252.PFREUD_05740 6.5e-156 556.6 Propionibacteriales rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK7R@201174,4DN2A@85009,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity gnl|extdb|FAM14217-p1-1.1_002078 754252.PFREUD_05730 3.6e-51 207.2 Propionibacteriales rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ7V@201174,4DR9N@85009,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome gnl|extdb|FAM14217-p1-1.1_002079 754252.PFREUD_05720 1.4e-122 445.7 Propionibacteriales rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02926 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJYJ@201174,4DN59@85009,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel gnl|extdb|FAM14217-p1-1.1_002080 754252.PFREUD_05710 1.1e-118 432.6 Propionibacteriales rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJXT@201174,4DNWZ@85009,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit gnl|extdb|FAM14217-p1-1.1_002081 754252.PFREUD_05700 7.3e-52 209.5 Propionibacteriales rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRA@201174,4DQJR@85009,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes gnl|extdb|FAM14217-p1-1.1_002082 754252.PFREUD_05690 6.6e-167 593.2 Actinobacteria pabC 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GN5Z@201174,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase gnl|extdb|FAM14217-p1-1.1_002083 754252.PFREUD_24670 8.2e-190 669.5 Propionibacteriales ko:K07497 ko00000 Bacteria 2GJ3V@201174,4DUKR@85009,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome gnl|extdb|FAM14217-p1-1.1_002084 754252.PFREUD_05680 3.3e-288 996.9 Propionibacteriales gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iNJ661.Rv2992c Bacteria 2GJJS@201174,4DPQP@85009,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gnl|extdb|FAM14217-p1-1.1_002085 754252.PFREUD_05670 1.1e-109 402.5 Actinobacteria Bacteria 2IIEK@201174,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM14217-p1-1.1_002086 754252.PFREUD_05660 2.5e-259 901.0 Actinobacteria 2.7.13.3 ko:K07778 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GKJJ@201174,COG3463@1,COG3463@2 NA|NA|NA S membrane gnl|extdb|FAM14217-p1-1.1_002087 754252.PFREUD_05650 1.8e-228 798.1 Propionibacteriales tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02358 ko00000,ko03012,ko03029,ko04147 Bacteria 2GK4T@201174,4DP42@85009,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis gnl|extdb|FAM14217-p1-1.1_002088 754252.PFREUD_05640 0.0 1406.0 Propionibacteriales fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 2GKB3@201174,4DNTK@85009,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome gnl|extdb|FAM14217-p1-1.1_002089 754252.PFREUD_05630 4.7e-79 300.4 Propionibacteriales rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMVW@201174,4DQ8Q@85009,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA gnl|extdb|FAM14217-p1-1.1_002090 754252.PFREUD_05620 1e-60 239.2 Propionibacteriales rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHUF@201174,4DQR6@85009,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit gnl|extdb|FAM14217-p1-1.1_002091 754252.PFREUD_05610 0.0 2503.8 Propionibacteriales rpoC GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GKWF@201174,4DP2S@85009,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM14217-p1-1.1_002092 754252.PFREUD_05600 0.0 2334.7 Propionibacteriales rpoB GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJ81@201174,4DMYN@85009,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM14217-p1-1.1_002094 754252.PFREUD_05580 3e-42 177.9 Propionibacteriales rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKNW@201174,4DQS8@85009,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation gnl|extdb|FAM14217-p1-1.1_002095 754252.PFREUD_05570 1.4e-94 352.4 Propionibacteriales rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM0V@201174,4DQF9@85009,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors gnl|extdb|FAM14217-p1-1.1_002096 754252.PFREUD_05560 4.6e-166 590.5 Propionibacteriales lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 2GKD4@201174,4DPBB@85009,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives gnl|extdb|FAM14217-p1-1.1_002097 754252.PFREUD_05550 9.2e-161 572.8 Propionibacteriales lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181,2.8.1.8 ko:K03644,ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07767,R07768,R07769 RC00039,RC00992,RC01978,RC02867 ko00000,ko00001,ko01000 iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 Bacteria 2GJIX@201174,4DPMN@85009,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate gnl|extdb|FAM14217-p1-1.1_002098 754252.PFREUD_05540 3.2e-127 461.1 Propionibacteriales rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM51@201174,4DNBG@85009,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release gnl|extdb|FAM14217-p1-1.1_002099 754252.PFREUD_05530 1.1e-69 269.2 Propionibacteriales rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFCK@201174,4DQC0@85009,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors gnl|extdb|FAM14217-p1-1.1_002100 754252.PFREUD_05520 1.1e-150 539.3 Propionibacteriales nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2GJFW@201174,4DPR5@85009,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination gnl|extdb|FAM14217-p1-1.1_002104 754252.PFREUD_05480 7.1e-214 749.6 Propionibacteriales murB GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 iECED1_1282.ECED1_4683,iECUMN_1333.ECUMN_4498_AT6,iLF82_1304.LF82_1416,iNRG857_1313.NRG857_19845 Bacteria 2GIV2@201174,4DNF7@85009,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation gnl|extdb|FAM14217-p1-1.1_002105 754252.PFREUD_05470 1.5e-76 292.0 Propionibacteriales hadB Bacteria 2IFCJ@201174,4DRH0@85009,COG2030@1,COG2030@2 NA|NA|NA I MaoC like domain gnl|extdb|FAM14217-p1-1.1_002106 754252.PFREUD_05460 1.3e-75 288.9 Propionibacteriales Bacteria 2GMVC@201174,4DRU6@85009,COG2030@1,COG2030@2 NA|NA|NA I N-terminal half of MaoC dehydratase gnl|extdb|FAM14217-p1-1.1_002107 754252.PFREUD_05450 5.4e-25 119.4 Actinobacteria rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFG@201174,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family gnl|extdb|FAM14217-p1-1.1_002110 754252.PFREUD_05420 1.7e-309 1067.8 Propionibacteriales ahpF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 ko:K03387 ko00000,ko01000 Bacteria 2H4AX@201174,4DWPW@85009,COG3634@1,COG3634@2 NA|NA|NA O Pyridine nucleotide-disulphide oxidoreductase gnl|extdb|FAM14217-p1-1.1_002114 754252.PFREUD_05380 2.9e-184 651.0 Propionibacteriales exoA 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKIS@201174,4DNS6@85009,COG0708@1,COG0708@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family gnl|extdb|FAM14217-p1-1.1_002116 754252.PFREUD_05360 9.8e-302 1042.0 Propionibacteriales ko:K14337,ko:K14339 ko00000,ko01000,ko01003 Bacteria 2DBIT@1,2GN9J@201174,2Z9GU@2,4DTW6@85009 NA|NA|NA S Carotene biosynthesis associated membrane protein gnl|extdb|FAM14217-p1-1.1_002117 754252.PFREUD_05350 0.0 1225.3 Propionibacteriales korA 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXV@201174,4DPBE@85009,COG0674@1,COG0674@2,COG1014@1,COG1014@2 NA|NA|NA C ferredoxin oxidoreductase gnl|extdb|FAM14217-p1-1.1_002118 754252.PFREUD_05340 1.8e-206 724.9 Propionibacteriales korB 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GMI5@201174,4DQ3H@85009,COG1013@1,COG1013@2 NA|NA|NA C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain gnl|extdb|FAM14217-p1-1.1_002119 754252.PFREUD_05330 0.0 1355.9 Propionibacteriales pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 2GNJY@201174,4DQ4I@85009,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 gnl|extdb|FAM14217-p1-1.1_002120 754252.PFREUD_05320 1.5e-111 409.8 Bacteria Bacteria COG3152@1,COG3152@2 NA|NA|NA L Membrane gnl|extdb|FAM14217-p1-1.1_002121 754252.PFREUD_05310 5.2e-83 313.5 Bacteria Bacteria COG3152@1,COG3152@2 NA|NA|NA L Membrane gnl|extdb|FAM14217-p1-1.1_002123 754252.PFREUD_05290 1.6e-277 961.4 Propionibacteriales nuoN GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GMGX@201174,4DNIM@85009,COG1007@1,COG1007@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM14217-p1-1.1_002124 754252.PFREUD_05280 2.5e-278 964.1 Propionibacteriales nuoM GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iSDY_1059.SDY_2473 Bacteria 2GKBN@201174,4DPXE@85009,COG1008@1,COG1008@2 NA|NA|NA C Proton-conducting membrane transporter gnl|extdb|FAM14217-p1-1.1_002126 754252.PFREUD_05260 4.5e-43 180.3 Propionibacteriales nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340,ko:K05576 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IKV7@201174,4DRR0@85009,COG0713@1,COG0713@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM14217-p1-1.1_002127 754252.PFREUD_05250 1.5e-134 485.7 Propionibacteriales nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GKRS@201174,4DPPF@85009,COG0839@1,COG0839@2 NA|NA|NA C Belongs to the complex I subunit 6 family gnl|extdb|FAM14217-p1-1.1_002128 754252.PFREUD_05240 3e-112 411.0 Propionibacteriales nuoI GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 ko:K00337,ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iNJ661.Rv3153 Bacteria 2GJNU@201174,4DP1W@85009,COG1143@1,COG1143@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM14217-p1-1.1_002129 754252.PFREUD_05230 1.8e-259 901.4 Propionibacteriales nuoH 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 iNJ661.Rv3152 Bacteria 2GIVY@201174,4DNAD@85009,COG1005@1,COG1005@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone gnl|extdb|FAM14217-p1-1.1_002130 754252.PFREUD_05220 0.0 1570.8 Propionibacteriales nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GJGX@201174,4DNGW@85009,COG1034@1,COG1034@2 NA|NA|NA C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region gnl|extdb|FAM14217-p1-1.1_002131 754252.PFREUD_05210 2e-268 931.0 Propionibacteriales nuoF 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GMMC@201174,4DPP6@85009,COG1894@1,COG1894@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain gnl|extdb|FAM14217-p1-1.1_002132 754252.PFREUD_05200 3.3e-135 487.6 Propionibacteriales nuoE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 ko:K00334,ko:K00335,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 Bacteria 2GKG0@201174,4DN2R@85009,COG1905@1,COG1905@2 NA|NA|NA C Thioredoxin-like [2Fe-2S] ferredoxin gnl|extdb|FAM14217-p1-1.1_002133 754252.PFREUD_05190 1.3e-265 921.8 Propionibacteriales nuoD 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GKEZ@201174,4DPY1@85009,COG0649@1,COG0649@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM14217-p1-1.1_002134 754252.PFREUD_05180 2.4e-149 534.6 Propionibacteriales nuoC GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GIRH@201174,4DPNJ@85009,COG0852@1,COG0852@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM14217-p1-1.1_002135 754252.PFREUD_05170 3.5e-105 387.5 Propionibacteriales nuoB 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GJXR@201174,4DNIV@85009,COG0377@1,COG0377@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM14217-p1-1.1_002136 754252.PFREUD_05160 3.5e-61 240.7 Propionibacteriales nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044464,GO:0050136,GO:0055114,GO:0071944,GO:0098796,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2IKWT@201174,4DR0D@85009,COG0838@1,COG0838@2 NA|NA|NA C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient gnl|extdb|FAM14217-p1-1.1_002138 754252.PFREUD_05130 4.1e-239 833.6 Propionibacteriales menF 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKE8@201174,4DPGF@85009,COG1169@1,COG1169@2 NA|NA|NA HQ Isochorismate synthase gnl|extdb|FAM14217-p1-1.1_002140 754252.PFREUD_05110 8.6e-122 443.0 Propionibacteriales ccmA 3.6.3.27,3.6.3.55 ko:K01990,ko:K06021,ko:K06857 ko02010,map02010 M00186,M00254 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.6.2,3.A.1.6.4 Bacteria 2IJGC@201174,4DQSV@85009,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM14217-p1-1.1_002141 754252.PFREUD_05100 1.3e-130 472.6 Propionibacteriales ubiE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0040007,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Bacteria 2GKFZ@201174,4DNP2@85009,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) gnl|extdb|FAM14217-p1-1.1_002142 754252.PFREUD_05090 0.0 1203.0 Propionibacteriales Bacteria 2HF5B@201174,4DWCJ@85009,COG2251@1,COG2251@2 NA|NA|NA V RNase_H superfamily gnl|extdb|FAM14217-p1-1.1_002143 754252.PFREUD_05080 1.4e-135 489.2 Propionibacteriales menA GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737 Bacteria 2GJBS@201174,4DNAI@85009,COG1575@1,COG1575@2 NA|NA|NA H Belongs to the MenA family. Type 1 subfamily gnl|extdb|FAM14217-p1-1.1_002144 1122994.AUFR01000005_gene826 7.6e-15 86.3 Propionibacteriales Bacteria 2EGDD@1,2HKYH@201174,33A58@2,4DSSA@85009 NA|NA|NA S Phospholipase_D-nuclease N-terminal gnl|extdb|FAM14217-p1-1.1_002146 754252.PFREUD_05040 7.1e-60 236.5 Actinobacteria puhA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 ko:K13991 ko02020,map02020 ko00000,ko00001,ko00194 Bacteria 2II0U@201174,COG3861@1,COG3861@2 NA|NA|NA S protein conserved in bacteria gnl|extdb|FAM14217-p1-1.1_002147 754252.PFREUD_05030 1.2e-87 328.9 Actinobacteria dcdA 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 2IJ94@201174,COG2131@1,COG2131@2 NA|NA|NA F Deoxycytidylate deaminase gnl|extdb|FAM14217-p1-1.1_002149 1122994.AUFR01000005_gene830 7.8e-142 510.8 Bacteria ko:K07001 ko00000 Bacteria COG1752@1,COG1752@2 NA|NA|NA M Esterase of the alpha-beta hydrolase superfamily gnl|extdb|FAM14217-p1-1.1_002150 754252.PFREUD_04990 5.3e-59 233.4 Bacteria puhA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 ko:K13991 ko02020,map02020 ko00000,ko00001,ko00194 Bacteria COG3861@1,COG3861@2 NA|NA|NA S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity gnl|extdb|FAM14217-p1-1.1_002152 754252.PFREUD_04970 1.2e-194 685.6 Propionibacteriales tal GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMF9@201174,4DN6D@85009,COG0176@1,COG0176@2 NA|NA|NA G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway gnl|extdb|FAM14217-p1-1.1_002156 754252.PFREUD_04930 1.3e-223 781.9 Propionibacteriales aspB Bacteria 2GJ7R@201174,4DPVC@85009,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II gnl|extdb|FAM14217-p1-1.1_002157 754252.PFREUD_04920 0.0 1155.6 Actinobacteria 3.6.3.3,3.6.3.5,3.6.3.54 ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 Bacteria 2GIRF@201174,COG2217@1,COG2217@2 NA|NA|NA P Heavy metal translocating P-type atpase gnl|extdb|FAM14217-p1-1.1_002158 754252.PFREUD_04910 5.6e-71 273.5 Actinobacteria Bacteria 2IMCT@201174,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator ArsR gnl|extdb|FAM14217-p1-1.1_002160 754252.PFREUD_04890 3.3e-106 391.3 Actinobacteria Bacteria 2GP2Z@201174,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_002162 754252.PFREUD_04860 9.8e-141 506.1 Actinobacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IITR@201174,COG0842@1,COG0842@2 NA|NA|NA V Abc-2 type transporter gnl|extdb|FAM14217-p1-1.1_002163 754252.PFREUD_04850 1.9e-274 951.4 Propionibacteriales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GIWB@201174,4DQU1@85009,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family gnl|extdb|FAM14217-p1-1.1_002167 754252.PFREUD_04810 6.8e-214 749.6 Propionibacteriales Bacteria 2GIVB@201174,4DP02@85009,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 gnl|extdb|FAM14217-p1-1.1_002168 754252.PFREUD_04800 6e-35 152.9 Bacteria Bacteria 2EGRW@1,33AI2@2 NA|NA|NA S Protein of unknown function (DUF3073) gnl|extdb|FAM14217-p1-1.1_002169 754252.PFREUD_04780 1.1e-197 695.7 Propionibacteriales purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 2GJNY@201174,4DMYH@85009,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase gnl|extdb|FAM14217-p1-1.1_002170 754252.PFREUD_04770 1.7e-298 1031.2 Propionibacteriales purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GK6I@201174,4DN2S@85009,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine gnl|extdb|FAM14217-p1-1.1_002171 585198.HMPREF0574_0665 3e-07 62.8 Actinobacteria Bacteria 2GY2S@201174,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM14217-p1-1.1_002172 754252.PFREUD_04750 2.9e-41 174.1 Actinobacteria 1.1.1.3 ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2IKS1@201174,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family gnl|extdb|FAM14217-p1-1.1_002173 754252.PFREUD_04740 4.5e-247 860.1 Actinobacteria XK27_08635 ko:K09157 ko00000 Bacteria 2HHMF@201174,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein gnl|extdb|FAM14217-p1-1.1_002174 754252.PFREUD_04730 4.6e-97 360.5 Actinobacteria ko:K07028 ko00000 Bacteria 2IKMM@201174,COG0645@1,COG0645@2 NA|NA|NA S AAA domain gnl|extdb|FAM14217-p1-1.1_002175 754252.PFREUD_04720 0.0 1096.6 Propionibacteriales fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GT0X@201174,4DPF3@85009,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family gnl|extdb|FAM14217-p1-1.1_002176 1120954.ATXE01000004_gene98 3.8e-23 114.8 Propionibacteriales Bacteria 2DM0Y@1,2IMIX@201174,318KY@2,4DS97@85009 NA|NA|NA S Domain of unknown function (DUF1992) gnl|extdb|FAM14217-p1-1.1_002177 754252.PFREUD_04690 2.3e-259 901.0 Propionibacteriales argE Bacteria 2GM84@201174,4DMZ8@85009,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain gnl|extdb|FAM14217-p1-1.1_002178 754252.PFREUD_04680 0.0 1520.8 Propionibacteriales purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKG6@201174,4DN9Q@85009,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM14217-p1-1.1_002179 754252.PFREUD_04670 9.7e-172 609.4 Propionibacteriales gspK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 R01961 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GKBF@201174,4DSI3@85009,COG2971@1,COG2971@2 NA|NA|NA G BadF/BadG/BcrA/BcrD ATPase family gnl|extdb|FAM14217-p1-1.1_002180 754252.PFREUD_04660 4.9e-62 243.8 Propionibacteriales hspR ko:K13640 ko00000,ko03000 Bacteria 2IQJ4@201174,4DVMZ@85009,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM14217-p1-1.1_002181 754252.PFREUD_04650 4.5e-195 687.2 Propionibacteriales dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2GJKK@201174,4DNFB@85009,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins gnl|extdb|FAM14217-p1-1.1_002182 754252.PFREUD_04640 9.4e-110 402.9 Propionibacteriales grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K02652,ko:K03687 ko00000,ko02035,ko02044,ko03029,ko03110 3.A.15.2 Bacteria 2GP4F@201174,4DRAF@85009,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ gnl|extdb|FAM14217-p1-1.1_002183 754252.PFREUD_04630 0.0 1109.4 Propionibacteriales dnaK ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2GJTY@201174,4DP1V@85009,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein gnl|extdb|FAM14217-p1-1.1_002184 754252.PFREUD_04620 7.7e-163 579.7 Propionibacteriales gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2DH@201174,4DN6Y@85009,COG1023@1,COG1023@2 NA|NA|NA G 6-phosphogluconate dehydrogenase, decarboxylating gnl|extdb|FAM14217-p1-1.1_002185 754252.PFREUD_04610 1.1e-232 812.4 Propionibacteriales gntP ko:K03299 ko00000,ko02000 2.A.8 Bacteria 2GITQ@201174,4DN1V@85009,COG2610@1,COG2610@2 NA|NA|NA EG GntP family permease gnl|extdb|FAM14217-p1-1.1_002186 754252.PFREUD_04600 4e-136 490.7 Propionibacteriales gntR ko:K19776 ko00000,ko03000 Bacteria 2GKBM@201174,4DQBS@85009,COG2186@1,COG2186@2 NA|NA|NA K FCD gnl|extdb|FAM14217-p1-1.1_002187 754252.PFREUD_04590 7.8e-126 456.4 Actinobacteria cbiM GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02007 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 2GK2U@201174,COG0310@1,COG0310@2 NA|NA|NA P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import gnl|extdb|FAM14217-p1-1.1_002188 754252.PFREUD_04580 1.3e-66 259.2 Actinobacteria cbiN GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02009 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18 Bacteria 2GRJ6@201174,COG1930@1,COG1930@2 NA|NA|NA P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import gnl|extdb|FAM14217-p1-1.1_002189 754252.PFREUD_04570 2.6e-138 498.0 Propionibacteriales cbiQ GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02008 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 2GP2M@201174,4DQAX@85009,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein gnl|extdb|FAM14217-p1-1.1_002190 754252.PFREUD_04560 3.8e-162 577.4 Propionibacteriales cbiO GO:0000041,GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006824,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0022857,GO:0030001,GO:0030554,GO:0031224,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072511,GO:0090482,GO:0097159,GO:0097367,GO:0098533,GO:0098656,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902494,GO:1902495,GO:1904949,GO:1990351 2.1.1.195 ko:K02006,ko:K02188,ko:K16786 ko00860,ko01100,ko02010,map00860,map01100,map02010 M00245,M00246,M00582 R07773 RC00003,RC02051 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4DN9V@85009,COG1122@1,COG1122@2 NA|NA|NA P Part of an ABC transporter complex. Responsible for energy coupling to the transport system gnl|extdb|FAM14217-p1-1.1_002191 754252.PFREUD_04550 3.8e-142 510.8 Propionibacteriales cysG GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.3,4.99.1.4 ko:K02302,ko:K02303,ko:K02304,ko:K03795,ko:K04719,ko:K13542 ko00740,ko00860,ko01100,ko01110,ko01120,map00740,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947,R05807,R09083 RC00003,RC00435,RC00871,RC01012,RC01034,RC01861,RC02413 ko00000,ko00001,ko00002,ko01000 iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158 Bacteria 2GK3B@201174,4DN4H@85009,COG0007@1,COG0007@2 NA|NA|NA H Tetrapyrrole (Corrin/Porphyrin) Methylases gnl|extdb|FAM14217-p1-1.1_002192 754252.PFREUD_04540 0.0 1574.7 Propionibacteriales hrpB 3.6.4.13 ko:K03579 ko00000,ko01000 Bacteria 2GMAW@201174,4DPC5@85009,COG1643@1,COG1643@2 NA|NA|NA L ATP-dependent helicase HrpB gnl|extdb|FAM14217-p1-1.1_002193 754252.PFREUD_04530 0.0 1176.8 Actinobacteria Bacteria 2GKB5@201174,COG4425@1,COG4425@2 NA|NA|NA S membrane gnl|extdb|FAM14217-p1-1.1_002194 754252.PFREUD_04520 2.3e-110 404.8 Propionibacteriales ko:K07118 ko00000 Bacteria 2GK2P@201174,4DS5Q@85009,COG2910@1,COG2910@2 NA|NA|NA S NmrA-like family gnl|extdb|FAM14217-p1-1.1_002195 754252.PFREUD_04510 3.6e-111 407.5 Propionibacteriales ko:K07118 ko00000 Bacteria 2GK2P@201174,4DS5Q@85009,COG2910@1,COG2910@2 NA|NA|NA S NmrA-like family gnl|extdb|FAM14217-p1-1.1_002197 754252.PFREUD_04490 7e-202 709.9 Propionibacteriales pitA ko:K03306 ko00000 2.A.20 Bacteria 2GJHK@201174,4DND5@85009,COG0306@1,COG0306@2 NA|NA|NA P Phosphate transporter family gnl|extdb|FAM14217-p1-1.1_002198 754252.PFREUD_04480 2.4e-133 481.5 Actinobacteria Bacteria 2DBXI@1,2GJN1@201174,2ZBQ3@2 NA|NA|NA S membrane gnl|extdb|FAM14217-p1-1.1_002199 754252.PFREUD_04470 1e-78 299.3 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity gnl|extdb|FAM14217-p1-1.1_002201 888056.HMPREF9062_1141 3.2e-08 64.3 Actinobacteria Bacteria 2EEPW@1,2HMSD@201174,338HK@2,4D7GV@85005 NA|NA|NA S SnoaL-like domain gnl|extdb|FAM14217-p1-1.1_002202 754252.PFREUD_04440 0.0 1115.1 Propionibacteriales ko:K03316 ko00000 2.A.36 Bacteria 2GIUT@201174,4DPNW@85009,COG0025@1,COG0025@2 NA|NA|NA P Sodium/hydrogen exchanger family gnl|extdb|FAM14217-p1-1.1_002203 754252.PFREUD_04430 0.0 1150.6 Propionibacteriales poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 2GJ20@201174,4DQ50@85009,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM14217-p1-1.1_002206 754252.PFREUD_04400 4.3e-59 233.8 Bacteria Bacteria 292E4@1,2ZPYC@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002207 754252.PFREUD_04390 2.8e-297 1027.3 Propionibacteriales aer ko:K03776 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 2IECR@201174,4DV3X@85009,COG0840@1,COG0840@2 NA|NA|NA NT Psort location gnl|extdb|FAM14217-p1-1.1_002208 754252.PFREUD_04380 1e-189 669.5 Propionibacteriales add GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 R01560,R02556 RC00477 ko00000,ko00001,ko01000 Bacteria 2GKJP@201174,4DN6T@85009,COG1816@1,COG1816@2 NA|NA|NA F adenosine deaminase gnl|extdb|FAM14217-p1-1.1_002210 754252.PFREUD_04360 0.0 1673.3 Propionibacteriales sbcC GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006260,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576 ko:K03546 ko00000,ko03400 Bacteria 2GKYR@201174,4DNWN@85009,COG0419@1,COG0419@2 NA|NA|NA L Putative exonuclease SbcCD, C subunit gnl|extdb|FAM14217-p1-1.1_002211 888439.HMPREF9240_01877 3e-07 62.0 Actinobacteria Bacteria 2ASGE@1,2HMEQ@201174,31HWJ@2,4D6VV@85005 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002212 754252.PFREUD_04340 4.3e-242 843.6 Actinobacteria Bacteria 2GRKM@201174,COG1075@1,COG1075@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold gnl|extdb|FAM14217-p1-1.1_002213 754252.PFREUD_04330 2.6e-219 767.7 Propionibacteriales Bacteria 2HY9F@201174,4DTUE@85009,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain gnl|extdb|FAM14217-p1-1.1_002214 754252.PFREUD_04320 0.0 1848.9 Propionibacteriales dld ko:K18930 ko00000 Bacteria 2GKI9@201174,4DU4S@85009,COG0247@1,COG0247@2,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain gnl|extdb|FAM14217-p1-1.1_002215 754252.PFREUD_04310 2.2e-224 784.6 Propionibacteriales ampC Bacteria 2GJQG@201174,4DPYC@85009,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM14217-p1-1.1_002216 754252.PFREUD_04300 9.9e-114 416.4 Actinobacteria sanA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 ko:K03748 ko00000 Bacteria 2GWVK@201174,COG2949@1,COG2949@2 NA|NA|NA S membrane gnl|extdb|FAM14217-p1-1.1_002217 754252.PFREUD_04290 0.0 1121.7 Propionibacteriales pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJG0@201174,4DPRV@85009,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family gnl|extdb|FAM14217-p1-1.1_002219 754252.PFREUD_04270 2.7e-115 421.4 Bacteria kdgA 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria COG0800@1,COG0800@2 NA|NA|NA G 2-dehydro-3-deoxy-phosphogluconate aldolase activity gnl|extdb|FAM14217-p1-1.1_002220 754252.PFREUD_04260 0.0 1691.8 Propionibacteriales ko:K03727 ko00000,ko01000 Bacteria 2GJSV@201174,4DPKV@85009,COG4581@1,COG4581@2 NA|NA|NA L DEAD DEAH box helicase gnl|extdb|FAM14217-p1-1.1_002221 754252.PFREUD_04250 5.2e-86 323.6 Actinobacteria ko:K06910 ko00000 Bacteria 2GMIG@201174,COG1881@1,COG1881@2 NA|NA|NA S Phospholipid-binding protein gnl|extdb|FAM14217-p1-1.1_002222 754252.PFREUD_04240 5.2e-218 763.5 Bacteria Bacteria COG2267@1,COG2267@2 NA|NA|NA I carboxylic ester hydrolase activity gnl|extdb|FAM14217-p1-1.1_002223 754252.PFREUD_04230 2.3e-119 434.9 Propionibacteriales Bacteria 2EKVV@1,2GYGM@201174,33EJD@2,4DW0T@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002230 754252.PFREUD_04080 4.1e-98 364.8 Bacteria Bacteria 2E461@1,32Z21@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002232 754252.PFREUD_04060 1.4e-21 110.2 Actinobacteria Bacteria 2IJCG@201174,COG3064@1,COG3064@2 NA|NA|NA M Host cell surface-exposed lipoprotein gnl|extdb|FAM14217-p1-1.1_002233 754252.PFREUD_04050 3.2e-129 467.6 Propionibacteriales purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJY@201174,4DNEU@85009,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM14217-p1-1.1_002234 754252.PFREUD_04040 2e-36 157.9 Propionibacteriales purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 2GQV4@201174,4DS4C@85009,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM14217-p1-1.1_002235 754252.PFREUD_04030 7.1e-169 599.7 Propionibacteriales purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K01945,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GK3H@201174,4DP92@85009,COG0152@1,COG0152@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM14217-p1-1.1_002236 754252.PFREUD_04020 7e-206 723.0 Bacteria yciQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria COG4907@1,COG4907@2 NA|NA|NA P membrane protein (DUF2207) gnl|extdb|FAM14217-p1-1.1_002237 754252.PFREUD_04010 7e-267 926.0 Propionibacteriales purB 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKBR@201174,4DNYZ@85009,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily gnl|extdb|FAM14217-p1-1.1_002239 754252.PFREUD_03990 7.9e-288 995.7 Actinobacteria ko:K03281,ko:K07085 ko00000 2.A.49,2.A.81 Bacteria 2GKDW@201174,COG0569@1,COG0569@2,COG2985@1,COG2985@2 NA|NA|NA P TrkA C-terminal domain protein gnl|extdb|FAM14217-p1-1.1_002243 754252.PFREUD_03940 4.2e-306 1056.6 Propionibacteriales MA20_25180 Bacteria 2GK06@201174,4DQV2@85009,COG0477@1,COG0477@2 NA|NA|NA EGP Transmembrane secretion effector gnl|extdb|FAM14217-p1-1.1_002245 754252.PFREUD_03920 3e-176 624.4 Propionibacteriales frk 2.7.1.20,2.7.1.4 ko:K00847,ko:K00856 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 R00185,R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GYHF@201174,4DQSX@85009,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM14217-p1-1.1_002247 754252.PFREUD_03900 0.0 1221.5 Actinobacteria 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2I2ZR@201174,COG2898@1,COG2898@2 NA|NA|NA S Uncharacterised conserved protein (DUF2156) gnl|extdb|FAM14217-p1-1.1_002248 754252.PFREUD_03890 0.0 1192.6 Propionibacteriales murJ ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2GKN0@201174,4DNJI@85009,COG0728@1,COG0728@2 NA|NA|NA KLT MviN-like protein gnl|extdb|FAM14217-p1-1.1_002249 754252.PFREUD_03880 2e-228 798.1 Propionibacteriales ask 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN0G@201174,4DN2D@85009,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family gnl|extdb|FAM14217-p1-1.1_002250 754252.PFREUD_03870 2.5e-183 647.9 Actinobacteria ddhD Bacteria 2GKW0@201174,COG0673@1,COG0673@2 NA|NA|NA C Oxidoreductase gnl|extdb|FAM14217-p1-1.1_002251 754252.PFREUD_03860 0.0 2207.6 Propionibacteriales ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 2GK9M@201174,4DNYP@85009,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) gnl|extdb|FAM14217-p1-1.1_002253 754252.PFREUD_03840 1e-116 426.0 Propionibacteriales recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJY0@201174,4DP0B@85009,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO gnl|extdb|FAM14217-p1-1.1_002254 754252.PFREUD_03830 5.9e-46 189.9 Propionibacteriales ybaB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K09747 ko00000 Bacteria 2IRC4@201174,4DRUM@85009,COG0718@1,COG0718@2 NA|NA|NA L Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection gnl|extdb|FAM14217-p1-1.1_002256 754252.PFREUD_03810 2.5e-80 304.7 Propionibacteriales ylcC 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2HF6P@201174,4DWEQ@85009,COG3764@1,COG3764@2 NA|NA|NA M Sortase family gnl|extdb|FAM14217-p1-1.1_002257 1552123.EP57_04215 3.8e-07 63.2 Listeriaceae Bacteria 1TQBI@1239,26INB@186820,4HPCU@91061,COG4932@1,COG4932@2 NA|NA|NA M Collagen binding domain gnl|extdb|FAM14217-p1-1.1_002258 754252.PFREUD_03790 0.0 1568.5 Actinobacteria nirK 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 Bacteria 2GPUP@201174,COG2132@1,COG2132@2,COG4454@1,COG4454@2 NA|NA|NA Q Multicopper oxidase gnl|extdb|FAM14217-p1-1.1_002259 754252.PFREUD_03780 3.9e-208 730.7 Actinobacteria 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 Bacteria 2HG56@201174,COG4243@1,COG4243@2 NA|NA|NA Q Vitamin k epoxide reductase gnl|extdb|FAM14217-p1-1.1_002260 754252.PFREUD_03770 1.7e-140 505.8 Bacteria Bacteria COG2345@1,COG2345@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_002261 754252.PFREUD_03760 7.7e-48 196.1 Bacteria Bacteria COG4309@1,COG4309@2 NA|NA|NA D conserved protein (DUF2249) gnl|extdb|FAM14217-p1-1.1_002263 754252.PFREUD_03750 1.4e-242 845.1 Propionibacteriales ilvA GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1559 Bacteria 2GJAG@201174,4DP7V@85009,COG1171@1,COG1171@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA gnl|extdb|FAM14217-p1-1.1_002265 1132442.KB889752_gene244 4.7e-09 70.1 Bacillus Bacteria 1TTJI@1239,1ZQ6N@1386,4HF0S@91061,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain gnl|extdb|FAM14217-p1-1.1_002267 1147128.BAST_0980 7.3e-141 507.7 Actinobacteria Bacteria 2DBH4@1,2I8MI@201174,2Z97J@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002268 1348338.ADILRU_1159 1e-157 563.1 Actinobacteria dcm 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 2GJR6@201174,COG0270@1,COG0270@2 NA|NA|NA H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family gnl|extdb|FAM14217-p1-1.1_002270 754252.PFREUD_24430 1.2e-171 609.4 Propionibacteriales ko:K07497 ko00000 Bacteria 2IDYA@201174,4DWSB@85009,COG2801@1,COG2801@2 NA|NA|NA L 4.4 Phage-related function gnl|extdb|FAM14217-p1-1.1_002276 754252.PFREUD_03590 2.8e-113 414.8 Propionibacteriales Bacteria 2GJ38@201174,4DQTH@85009,COG2356@1,COG2356@2 NA|NA|NA L Protein of unknown function (DUF1524) gnl|extdb|FAM14217-p1-1.1_002277 754252.PFREUD_03560 0.0 1476.1 Propionibacteriales recQ1 Bacteria 2GJ4Y@201174,4DN78@85009,COG1061@1,COG1061@2,COG3886@1,COG3886@2 NA|NA|NA L Domain of unknown function (DUF3427) gnl|extdb|FAM14217-p1-1.1_002278 754252.PFREUD_03560 5.2e-164 583.6 Propionibacteriales recQ1 Bacteria 2GJ4Y@201174,4DN78@85009,COG1061@1,COG1061@2,COG3886@1,COG3886@2 NA|NA|NA L Domain of unknown function (DUF3427) gnl|extdb|FAM14217-p1-1.1_002280 1206733.BAGC01000110_gene6635 2.5e-07 61.6 Nocardiaceae Bacteria 2BKTU@1,2HZ4Z@201174,32FA2@2,4G4ZQ@85025 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002282 754252.PFREUD_03460 8.4e-120 436.8 Propionibacteriales ddpX 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 2GNX8@201174,4DSUC@85009,COG3786@1,COG3786@2 NA|NA|NA S protein conserved in bacteria gnl|extdb|FAM14217-p1-1.1_002283 754252.PFREUD_03450 2.4e-125 455.3 Actinobacteria XK27_08050 Bacteria 2GJ1U@201174,COG0330@1,COG0330@2 NA|NA|NA O PFAM Band 7 protein gnl|extdb|FAM14217-p1-1.1_002286 754252.PFREUD_03410 2.5e-172 611.3 Propionibacteriales czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 2GMRZ@201174,4DNBF@85009,COG1230@1,COG1230@2 NA|NA|NA P Cation efflux family gnl|extdb|FAM14217-p1-1.1_002287 754252.PFREUD_03400 9e-259 899.0 Actinobacteria aroP GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008104,GO:0008150,GO:0008320,GO:0008324,GO:0008509,GO:0008514,GO:0008565,GO:0009977,GO:0015031,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015291,GO:0015318,GO:0015399,GO:0015405,GO:0015450,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015833,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1904680,GO:1905039 ko:K03293,ko:K11732,ko:K11734 ko00000,ko02000 2.A.3.1,2.A.3.1.1,2.A.3.1.3 iAPECO1_1312.APECO1_1472,iECW_1372.ECW_m0628,iEcE24377_1341.EcE24377A_0114,iEcolC_1368.EcolC_3070,iJN746.PP_4495,iUTI89_1310.UTI89_C0576,iWFL_1372.ECW_m0628 Bacteria 2GJ0X@201174,COG1113@1,COG1113@2 NA|NA|NA E amino acid gnl|extdb|FAM14217-p1-1.1_002289 754252.PFREUD_03370 1.6e-154 552.0 Propionibacteriales thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 ko:K00788,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R04509,R10712 RC00002,RC00017,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iYO844.BSU38290 Bacteria 2GKCN@201174,4DSCS@85009,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) gnl|extdb|FAM14217-p1-1.1_002292 754252.PFREUD_03340 0.0 1094.0 Propionibacteriales aarF Bacteria 2GJQ6@201174,4DQX3@85009,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family gnl|extdb|FAM14217-p1-1.1_002293 754252.PFREUD_03330 5e-99 367.1 Propionibacteriales padR ko:K10947 ko00000,ko03000 Bacteria 2IFDN@201174,4DR1C@85009,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family gnl|extdb|FAM14217-p1-1.1_002295 754252.PFREUD_03310 1.3e-258 898.7 Bacteria Bacteria COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family gnl|extdb|FAM14217-p1-1.1_002296 754252.PFREUD_03300 1.9e-110 405.2 Propionibacteriales metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GY65@201174,4DQ48@85009,COG2011@1,COG2011@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_002297 754252.PFREUD_03290 2.7e-230 804.3 Propionibacteriales metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GJ9P@201174,4DPWT@85009,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system gnl|extdb|FAM14217-p1-1.1_002298 754252.PFREUD_03280 1.6e-153 548.9 Propionibacteriales metQ_3 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GMNI@201174,4DPJ9@85009,COG1464@1,COG1464@2 NA|NA|NA P NLPA lipoprotein gnl|extdb|FAM14217-p1-1.1_002299 754252.PFREUD_03270 1.8e-133 481.9 Propionibacteriales Bacteria 2GIZB@201174,4DNE1@85009,COG0745@1,COG0745@2 NA|NA|NA T response regulator gnl|extdb|FAM14217-p1-1.1_002300 754252.PFREUD_03260 0.0 1077.4 Propionibacteriales 2.7.13.3 ko:K02484,ko:K07768 ko02020,map02020 M00443 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2I2DU@201174,4DNGB@85009,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain gnl|extdb|FAM14217-p1-1.1_002301 754252.PFREUD_03250 6.1e-169 600.1 Actinobacteria rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2I04R@201174,COG0524@1,COG0524@2 NA|NA|NA G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway gnl|extdb|FAM14217-p1-1.1_002302 754252.PFREUD_03240 0.0 1255.0 Bacteria Bacteria COG1716@1,COG1716@2 NA|NA|NA T histone H2A K63-linked ubiquitination gnl|extdb|FAM14217-p1-1.1_002303 754252.PFREUD_03230 0.0 1699.1 Propionibacteriales ppdK 2.7.3.13,2.7.9.1 ko:K01006,ko:K22424 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK73@201174,4DPDB@85009,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Belongs to the PEP-utilizing enzyme family gnl|extdb|FAM14217-p1-1.1_002304 754252.PFREUD_03210 2.2e-165 588.2 Actinobacteria yqfL 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 2IDD1@201174,COG1806@1,COG1806@2 NA|NA|NA S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the gnl|extdb|FAM14217-p1-1.1_002305 754252.PFREUD_03200 9.3e-167 592.8 Actinobacteria mrr ko:K07448 ko00000,ko02048 Bacteria 2GP9K@201174,COG1715@1,COG1715@2 NA|NA|NA L Restriction endonuclease gnl|extdb|FAM14217-p1-1.1_002307 754252.PFREUD_03180 4.8e-190 670.2 Actinobacteria rlmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2I8VY@201174,COG2813@1,COG2813@2 NA|NA|NA J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA gnl|extdb|FAM14217-p1-1.1_002308 754252.PFREUD_03170 2.4e-136 491.5 Propionibacteriales ywiC Bacteria 28NT3@1,2IIC3@201174,2ZBRV@2,4DW8G@85009 NA|NA|NA S YwiC-like protein gnl|extdb|FAM14217-p1-1.1_002309 754252.PFREUD_03160 1.8e-161 575.1 Propionibacteriales dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Bacteria 2GJQ7@201174,4DN3W@85009,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family gnl|extdb|FAM14217-p1-1.1_002311 754252.PFREUD_03140 4.9e-114 417.2 Propionibacteriales Bacteria 2GKZR@201174,4DSEZ@85009,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family gnl|extdb|FAM14217-p1-1.1_002313 754252.PFREUD_03120 1.5e-225 788.5 Propionibacteriales Bacteria 2GJFV@201174,4DRPN@85009,COG4198@1,COG4198@2 NA|NA|NA S Protein of unknown function (DUF1015) gnl|extdb|FAM14217-p1-1.1_002314 754252.PFREUD_03110 1.2e-296 1025.0 Propionibacteriales cat1 GO:0003674,GO:0003824,GO:0003986,GO:0006082,GO:0006083,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008410,GO:0008775,GO:0009987,GO:0016289,GO:0016740,GO:0016782,GO:0016787,GO:0016788,GO:0016790,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043821,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0071704 2.8.3.18,3.1.2.1 ko:K01067,ko:K18118,ko:K22214 ko00020,ko00620,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00640,map00650,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00227,R10343,R11773 RC00004,RC00012,RC00014 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1125,iECIAI1_1343.ECIAI1_3040,iECSE_1348.ECSE_3182,iECW_1372.ECW_m3175,iEKO11_1354.EKO11_0812,iWFL_1372.ECW_m3175 Bacteria 2I9EB@201174,4DPYR@85009,COG0427@1,COG0427@2 NA|NA|NA C Acetyl-CoA hydrolase/transferase N-terminal domain gnl|extdb|FAM14217-p1-1.1_002315 754252.PFREUD_03100 5.4e-147 526.9 Propionibacteriales Bacteria 2GK20@201174,4DR4D@85009,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain gnl|extdb|FAM14217-p1-1.1_002316 754252.PFREUD_03090 2e-194 684.9 Propionibacteriales serA Bacteria 2GP09@201174,4DRRR@85009,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain gnl|extdb|FAM14217-p1-1.1_002317 754252.PFREUD_03080 3.2e-118 431.0 Bacteria ppaX 3.1.3.105,3.1.3.18,3.6.1.1 ko:K01091,ko:K06019,ko:K16017,ko:K22292 ko00190,ko00520,ko00630,ko01051,ko01100,ko01110,ko01130,map00190,map00520,map00630,map01051,map01100,map01110,map01130 R01334,R06587,R11785 RC00017,RC00078 ko00000,ko00001,ko01000 Bacteria COG0546@1,COG0546@2 NA|NA|NA S glycolate biosynthetic process gnl|extdb|FAM14217-p1-1.1_002318 754252.PFREUD_03070 8.6e-311 1072.0 Actinobacteria Bacteria 28MCF@1,2IDHH@201174,2ZAQK@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002319 1035308.AQYY01000001_gene1494 4.3e-12 78.6 Bacteria Bacteria 2DEXG@1,2ZPNB@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002323 710687.KI912270_gene4878 6.7e-11 75.1 Mycobacteriaceae Bacteria 23698@1762,2BWS4@1,2GR3P@201174,32XQ0@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002325 158787.BSCA_1068 1.9e-62 246.1 Bifidobacteriales Bacteria 2GJ9M@201174,4D0SC@85004,COG3023@1,COG3023@2 NA|NA|NA V Ami_2 gnl|extdb|FAM14217-p1-1.1_002328 66874.JOFS01000005_gene3848 2.3e-30 140.6 Actinobacteria scrB 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 2I3F1@201174,COG1621@1,COG1621@2 NA|NA|NA G acetyltransferase gnl|extdb|FAM14217-p1-1.1_002331 1463858.JOHR01000031_gene5567 2.5e-28 133.3 Actinobacteria Bacteria 2DWRB@1,2ID68@201174,341IF@2 NA|NA|NA S Domain of unknown function (DUF5047) gnl|extdb|FAM14217-p1-1.1_002340 1437608.BBIA_2150 5.6e-30 137.1 Bifidobacteriales Bacteria 2EEUJ@1,2IRIW@201174,338N2@2,4D1FY@85004 NA|NA|NA S Phage protein Gp19/Gp15/Gp42 gnl|extdb|FAM14217-p1-1.1_002342 1273125.Rrhod_1355 1.2e-111 409.8 Nocardiaceae Bacteria 2C8MZ@1,2I7QK@201174,2ZA7T@2,4G0U5@85025 NA|NA|NA S Family of unknown function (DUF5309) gnl|extdb|FAM14217-p1-1.1_002344 1095772.CAHH01000063_gene655 7.1e-40 171.0 Actinobacteria Bacteria 2DM1N@1,2IRH6@201174,31BIG@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002345 234621.RER_22740 2.5e-81 309.7 Nocardiaceae Bacteria 2C9AC@1,2I2HE@201174,2Z839@2,4G24S@85025 NA|NA|NA S Phage portal protein, SPP1 Gp6-like gnl|extdb|FAM14217-p1-1.1_002346 883077.HMPREF9241_01693 5.3e-129 468.0 Actinobacteria Bacteria 2IB7D@201174,4D4JH@85005,COG4626@1,COG4626@2 NA|NA|NA S Terminase gnl|extdb|FAM14217-p1-1.1_002348 1122238.AULR01000003_gene1343 3.7e-34 151.4 Bacteria Bacteria COG4983@1,COG4983@2 NA|NA|NA L Phage plasmid primase, P4 family domain protein gnl|extdb|FAM14217-p1-1.1_002349 471856.Jden_2304 4.5e-15 87.4 Bacteria ko:K07451 ko00000,ko01000,ko02048 Bacteria COG1403@1,COG1403@2 NA|NA|NA V endonuclease activity gnl|extdb|FAM14217-p1-1.1_002354 1463921.JODF01000103_gene5755 5.3e-30 137.5 Actinobacteria ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2IH2G@201174,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family gnl|extdb|FAM14217-p1-1.1_002356 1445613.JALM01000032_gene5163 1.6e-26 125.6 Bacteria Bacteria COG3756@1,COG3756@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_002357 1206741.BAFX01000186_gene6765 3.6e-37 161.0 Nocardiaceae Bacteria 2E0Z5@1,2IR2P@201174,32WFJ@2,4G3YU@85025 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000020 754252.PFREUD_02850 2.4e-123 448.7 Actinobacteria ko:K07052 ko00000 Bacteria 2IID1@201174,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM14217-p1-1.1_000026 754252.PFREUD_02790 8.8e-265 919.1 Actinobacteria ko:K03457 ko00000 2.A.39 Bacteria 2GJ6B@201174,COG1457@1,COG1457@2 NA|NA|NA F Belongs to the purine-cytosine permease (2.A.39) family gnl|extdb|FAM14217-p1-1.1_000027 754252.PFREUD_02780 1.5e-172 612.1 Actinobacteria yegV GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 Bacteria 2IA3T@201174,COG0524@1,COG0524@2 NA|NA|NA G Kinase, PfkB family gnl|extdb|FAM14217-p1-1.1_000040 754252.PFREUD_02600 3.6e-140 504.2 Propionibacteriales ppgK 2.7.1.2,2.7.1.63 ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786,R02187,R02189 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJA0@201174,4DQCW@85009,COG1940@1,COG1940@2 NA|NA|NA GK ROK family gnl|extdb|FAM14217-p1-1.1_000042 754252.PFREUD_02580 2.1e-161 575.1 Propionibacteriales ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GJB9@201174,4DTAG@85009,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM14217-p1-1.1_000049 754252.PFREUD_02550 0.0 1083.6 Propionibacteriales argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Bacteria 2GKQ3@201174,4DNTZ@85009,COG0018@1,COG0018@2 NA|NA|NA J Arginyl tRNA synthetase N terminal dom gnl|extdb|FAM14217-p1-1.1_000051 754252.PFREUD_02530 1.5e-112 412.1 Actinobacteria sanA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 ko:K03748 ko00000 Bacteria 2GWVK@201174,COG2949@1,COG2949@2 NA|NA|NA S membrane gnl|extdb|FAM14217-p1-1.1_000057 754252.PFREUD_02470 3.5e-117 427.6 Actinobacteria Bacteria 2GJ7I@201174,COG0491@1,COG0491@2 NA|NA|NA S Zn-dependent gnl|extdb|FAM14217-p1-1.1_000060 754252.PFREUD_02440 2e-310 1070.8 Actinobacteria caiC GO:0003674,GO:0003824,GO:0016405,GO:0016874,GO:0016877,GO:0016879,GO:0016881,GO:0051108,GO:0051109 6.2.1.48 ko:K02182 ko00000,ko01000 iECSE_1348.ECSE_0038,iNRG857_1313.NRG857_00195 Bacteria 2GIUC@201174,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM AMP-dependent synthetase and ligase gnl|extdb|FAM14217-p1-1.1_000063 754252.PFREUD_24470 2.6e-07 60.8 Actinobacteria ko:K07483,ko:K07497 ko00000 Bacteria 2IMAC@201174,COG2963@1,COG2963@2 NA|NA|NA L transposase activity gnl|extdb|FAM14217-p1-1.1_000100 754252.PFREUD_02170 2.7e-282 977.2 Propionibacteriales lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 2GKE0@201174,4DNHS@85009,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family gnl|extdb|FAM14217-p1-1.1_000103 754252.PFREUD_02140 7.9e-58 229.6 Actinobacteria Bacteria 2IR2V@201174,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain gnl|extdb|FAM14217-p1-1.1_000106 754252.PFREUD_02110 1.3e-114 419.1 Bacteria Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM14217-p1-1.1_000127 754252.PFREUD_01860 3.5e-268 930.6 Propionibacteriales ydcW 1.2.1.3,1.2.1.8 ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00555 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4DNGV@85009,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM14217-p1-1.1_000128 754252.PFREUD_01850 1.9e-189 668.3 Actinobacteria 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN1V@201174,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate gnl|extdb|FAM14217-p1-1.1_000129 754252.PFREUD_01840 0.0 2432.5 Propionibacteriales nifJ GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 iJN678.nifJ Bacteria 2I995@201174,4DVUV@85009,COG0674@1,COG0674@2,COG1013@1,COG1013@2,COG1014@1,COG1014@2 NA|NA|NA C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin gnl|extdb|FAM14217-p1-1.1_000141 754252.PFREUD_01700 9.2e-107 392.9 Propionibacteriales frcK ko:K02173 ko00000 Bacteria 2I9H4@201174,4DR2H@85009,COG0572@1,COG0572@2 NA|NA|NA F Fructose transport system kinase gnl|extdb|FAM14217-p1-1.1_000144 754252.PFREUD_01670 5.4e-38 163.7 Bacteria 2.7.7.76 ko:K06975,ko:K07141 ko00790,map00790 R11582 ko00000,ko00001,ko01000 Bacteria COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase gnl|extdb|FAM14217-p1-1.1_000147 754252.PFREUD_01640 4.2e-239 833.6 Propionibacteriales Bacteria 2GJEG@201174,4DN2N@85009,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM14217-p1-1.1_000151 754252.PFREUD_01600 3.5e-157 560.8 Propionibacteriales dkgA 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 2GJQ7@201174,4DT39@85009,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family gnl|extdb|FAM14217-p1-1.1_000166 754252.PFREUD_01450 1.7e-239 835.1 Actinobacteria Bacteria 2GJM3@201174,COG1316@1,COG1316@2 NA|NA|NA K cell envelope-related transcriptional attenuator gnl|extdb|FAM14217-p1-1.1_000171 754252.PFREUD_01400 2.5e-121 441.4 Propionibacteriales Bacteria 2GJE6@201174,4DNSE@85009,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver gnl|extdb|FAM14217-p1-1.1_000183 754252.PFREUD_01270 3.4e-261 907.1 Actinobacteria rbbA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0042623,GO:0043021,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060187,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112 ko:K01990,ko:K13926 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I778@201174,COG1129@1,COG1129@2 NA|NA|NA G ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_000187 754252.PFREUD_01220 1.7e-196 691.8 Actinobacteria 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IFVF@201174,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III gnl|extdb|FAM14217-p1-1.1_000201 754252.PFREUD_01140 7.1e-138 496.9 Propionibacteriales coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJGJ@201174,4DNHQ@85009,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine gnl|extdb|FAM14217-p1-1.1_000206 754252.PFREUD_00750 7.2e-225 786.2 Bacteria aslB GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 ko:K06871 ko00000 Bacteria COG0641@1,COG0641@2 NA|NA|NA C radical SAM gnl|extdb|FAM14217-p1-1.1_000211 754252.PFREUD_00800 4.9e-213 746.9 Propionibacteriales ybjJ_3 Bacteria 2I30D@201174,4DWGA@85009,COG2223@1,COG2223@2 NA|NA|NA P Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000212 754252.PFREUD_00810 1.5e-247 861.7 Propionibacteriales Bacteria 2GM17@201174,4DP7S@85009,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor gnl|extdb|FAM14217-p1-1.1_000266 754252.PFREUD_23400 1.1e-136 492.7 Propionibacteriales ugpA ko:K02025,ko:K05814,ko:K15771 ko02010,map02010 M00198,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3 Bacteria 2GKJI@201174,4DQWD@85009,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000269 754252.PFREUD_23430 4.1e-259 900.2 Actinobacteria bmr3 Bacteria 2H32P@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000273 754252.PFREUD_23470 5e-47 193.4 Propionibacteriales rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IQHD@201174,4DRPR@85009,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA gnl|extdb|FAM14217-p1-1.1_000302 754252.PFREUD_23610 2.5e-255 887.5 Propionibacteriales nplT Bacteria 2GJUT@201174,4DT3W@85009,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain gnl|extdb|FAM14217-p1-1.1_000317 754252.PFREUD_23920 1.2e-199 702.2 Propionibacteriales yghZ ko:K19265 ko00000,ko01000 Bacteria 2GMT5@201174,4DNMA@85009,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM14217-p1-1.1_000323 754252.PFREUD_23980 2e-50 204.9 Bacteria Bacteria COG4270@1,COG4270@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000340 754252.PFREUD_24150 3e-148 531.2 Propionibacteriales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GMU7@201174,4DNHI@85009,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ gnl|extdb|FAM14217-p1-1.1_000341 754252.PFREUD_24170 1.6e-137 495.4 Propionibacteriales rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 2GM9Z@201174,4DR7I@85009,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA gnl|extdb|FAM14217-p1-1.1_000352 754252.PFREUD_00060 1.7e-148 531.9 Propionibacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4DNEX@85009,COG1136@1,COG1136@2 NA|NA|NA V COG1136 ABC-type antimicrobial peptide transport system, ATPase component gnl|extdb|FAM14217-p1-1.1_000356 754252.PFREUD_00100 9.3e-80 302.8 Propionibacteriales Bacteria 2GNQ4@201174,4DR8Q@85009,COG5512@1,COG5512@2 NA|NA|NA S Protein of unknown function (DUF721) gnl|extdb|FAM14217-p1-1.1_000379 754252.PFREUD_00350 1.3e-277 961.8 Propionibacteriales ko:K02021,ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 2GJAP@201174,4DQK3@85009,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM14217-p1-1.1_000383 754252.PFREUD_00310 5.7e-115 420.2 Actinobacteria Bacteria 2GM61@201174,COG2197@1,COG2197@2 NA|NA|NA T response regulator gnl|extdb|FAM14217-p1-1.1_000396 754252.PFREUD_00180 7e-46 189.5 Actinobacteria Bacteria 2E7BZ@1,2GQHG@201174,331V9@2 NA|NA|NA S Domain of Unknown Function (DUF1540) gnl|extdb|FAM14217-p1-1.1_000399 754252.PFREUD_00150 0.0 1323.5 Propionibacteriales gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKGP@201174,4DN1A@85009,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gnl|extdb|FAM14217-p1-1.1_000411 754252.PFREUD_00600 3.3e-127 461.1 Propionibacteriales wzt 3.6.3.38 ko:K01990,ko:K09689 ko02010,map02010 M00249,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101 Bacteria 2GIVF@201174,4DP9X@85009,COG1134@1,COG1134@2 NA|NA|NA GM ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_000427 754252.PFREUD_23030 3.6e-163 580.9 Actinobacteria 3.4.21.62 ko:K01342,ko:K12287,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko02044,ko03110 Bacteria 2GK3D@201174,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family gnl|extdb|FAM14217-p1-1.1_000436 754252.PFREUD_22940 5.8e-142 510.4 Propionibacteriales pknD ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJQW@201174,4DQ7J@85009,COG0834@1,COG0834@2 NA|NA|NA ET amino acid gnl|extdb|FAM14217-p1-1.1_000455 754252.PFREUD_22780 5.3e-78 297.0 Propionibacteriales hsp20 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2IHVJ@201174,4DQU3@85009,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) gnl|extdb|FAM14217-p1-1.1_000468 450380.JPSY01000003_gene2738 2.1e-21 107.8 Microbacteriaceae Bacteria 2E9IE@1,2GTQZ@201174,333RF@2,4FSDS@85023 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000479 754252.PFREUD_22490 1.5e-239 835.1 Propionibacteriales Bacteria 2GIS1@201174,4DUJT@85009,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_000492 754252.PFREUD_22350 1.3e-58 231.9 Bacteria Bacteria COG4357@1,COG4357@2 NA|NA|NA S CHY zinc finger gnl|extdb|FAM14217-p1-1.1_000511 754252.PFREUD_22160 2.1e-148 531.6 Propionibacteriales fecB ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GYJE@201174,4DPCN@85009,COG0614@1,COG0614@2 NA|NA|NA P ABC-type Fe3 -hydroxamate transport system, periplasmic component gnl|extdb|FAM14217-p1-1.1_000535 223184.AS25_10320 1.2e-14 85.1 Micrococcaceae Bacteria 1WC1F@1268,2BFWH@1,2HTET@201174,329S0@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM14217-p1-1.1_000540 754252.PFREUD_22100 1.8e-162 578.6 Propionibacteriales virB11 ko:K02283,ko:K03196,ko:K12083 ko03070,ko05120,map03070,map05120 M00333,M00564 ko00000,ko00001,ko00002,ko02035,ko02044 3.A.7,3.A.7.3.1 Bacteria 2I3XU@201174,4DNAT@85009,COG0630@1,COG0630@2 NA|NA|NA NU Type II/IV secretion system protein gnl|extdb|FAM14217-p1-1.1_000554 754252.PFREUD_21920 9.5e-258 895.6 Actinobacteria gabT 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GIS9@201174,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gnl|extdb|FAM14217-p1-1.1_000555 754252.PFREUD_21910 7.5e-197 693.0 Actinobacteria 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2I3FK@201174,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM14217-p1-1.1_000568 754252.PFREUD_21790 1.8e-254 884.8 Actinobacteria moeA 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 2GJC3@201174,COG0303@1,COG0303@2 NA|NA|NA H Molybdenum cofactor synthesis domain protein gnl|extdb|FAM14217-p1-1.1_000571 1227261.HMPREF0043_01367 1.1e-67 263.8 Actinobacteria Bacteria 2GW1M@201174,4D3N7@85005,COG2345@1,COG2345@2 NA|NA|NA K Psort location Cytoplasmic, score gnl|extdb|FAM14217-p1-1.1_000581 1122994.AUFR01000060_gene620 4.2e-193 681.4 Propionibacteriales modB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.10.1.1,3.6.3.29,3.6.3.55 ko:K02017,ko:K02018,ko:K03750,ko:K15496,ko:K15497 ko00790,ko01100,ko02010,map00790,map01100,map02010 M00189,M00423 R09735,R10531 RC00002,RC03462 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.5,3.A.1.8 iECO103_1326.ECO103_0752 Bacteria 2GJFB@201174,4DPG9@85009,COG3842@1,COG3842@2,COG4149@1,COG4149@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000588 754252.PFREUD_21640 2.8e-190 671.0 Propionibacteriales cysD 1.8.4.10,1.8.4.8,2.7.7.4 ko:K00390,ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R02021,R04929 RC00007,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN85@201174,4DPJX@85009,COG0175@1,COG0175@2 NA|NA|NA EH Sulfate adenylyltransferase gnl|extdb|FAM14217-p1-1.1_000590 754252.PFREUD_21620 0.0 1127.1 Propionibacteriales sir GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,1.8.7.1 ko:K00366,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00531 R00790,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJRN@201174,4DP25@85009,COG0155@1,COG0155@2 NA|NA|NA C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family gnl|extdb|FAM14217-p1-1.1_000593 754252.PFREUD_21590 3.1e-131 474.6 Propionibacteriales cysW GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02046,ko:K02047 ko00920,ko02010,map00920,map02010 M00185 ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 iPC815.YPO3013 Bacteria 2GMTK@201174,4DNNA@85009,COG4208@1,COG4208@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM14217-p1-1.1_000611 754252.PFREUD_21430 2.4e-270 937.6 Actinobacteria ybhI ko:K03319 ko00000 2.A.47 Bacteria 2GVHZ@201174,COG0471@1,COG0471@2 NA|NA|NA P transporter gnl|extdb|FAM14217-p1-1.1_000626 1171373.PACID_00610 2.1e-114 419.1 Propionibacteriales moxR ko:K03924 ko00000,ko01000 Bacteria 2GK07@201174,4DNJJ@85009,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) gnl|extdb|FAM14217-p1-1.1_000633 754252.PFREUD_20950 3e-235 820.8 Propionibacteriales mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 2GJSM@201174,4DSP2@85009,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein gnl|extdb|FAM14217-p1-1.1_000636 754252.PFREUD_20920 7.5e-55 219.5 Actinobacteria Bacteria 2EJED@1,2GUI5@201174,33D5D@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000648 754252.PFREUD_20800 8.1e-69 266.9 Propionibacteriales csoR ko:K21600 ko00000,ko03000 Bacteria 2IQAC@201174,4DRND@85009,COG1937@1,COG1937@2 NA|NA|NA S Metal-sensitive transcriptional repressor gnl|extdb|FAM14217-p1-1.1_000667 754252.PFREUD_20610 0.0 1762.3 Propionibacteriales dmsA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.97.1.9 ko:K07306,ko:K07309,ko:K07310 ko00450,ko00920,map00450,map00920 R07229,R09501 RC02420,RC02555 ko00000,ko00001,ko01000,ko02000 5.A.3.3 iE2348C_1286.E2348C_1672,iECSE_1348.ECSE_0952,iNRG857_1313.NRG857_07945,iSFV_1184.SFV_1557,iZ_1308.Z1240 Bacteria 2GJCK@201174,4DPDY@85009,COG0243@1,COG0243@2 NA|NA|NA C Molydopterin dinucleotide binding domain gnl|extdb|FAM14217-p1-1.1_000675 754252.PFREUD_20530 8.2e-238 829.3 Propionibacteriales holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ8C@201174,4DNVR@85009,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III gnl|extdb|FAM14217-p1-1.1_000695 754252.PFREUD_20320 0.0 1584.7 Bacteria Bacteria COG0507@1,COG0507@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD gnl|extdb|FAM14217-p1-1.1_000698 754252.PFREUD_20290 3.2e-144 517.7 Propionibacteriales folP 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDQ@201174,4DPQM@85009,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives gnl|extdb|FAM14217-p1-1.1_000699 754252.PFREUD_20280 7.3e-56 223.0 Actinobacteria folB GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840 R03503,R03504,R11037,R11073 RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 2IHSW@201174,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin gnl|extdb|FAM14217-p1-1.1_000706 754252.PFREUD_20210 5.9e-108 396.7 Propionibacteriales pabB 2.6.1.85,4.1.3.27 ko:K01657,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2HQC8@201174,4DRP4@85009,COG0572@1,COG0572@2 NA|NA|NA F uridine kinase gnl|extdb|FAM14217-p1-1.1_000709 754252.PFREUD_20180 1.2e-100 372.5 Actinobacteria ykoE ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 2IDAN@201174,COG4721@1,COG4721@2 NA|NA|NA S membrane gnl|extdb|FAM14217-p1-1.1_000710 754252.PFREUD_20170 3.8e-162 577.4 Propionibacteriales mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJD9@201174,4DP1C@85009,COG1194@1,COG1194@2 NA|NA|NA L FES gnl|extdb|FAM14217-p1-1.1_000711 754252.PFREUD_20160 1.2e-186 659.1 Propionibacteriales disA 2.7.7.85 ko:K07067 ko00000,ko01000 Bacteria 2GJ41@201174,4DNMZ@85009,COG1623@1,COG1623@2 NA|NA|NA L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process gnl|extdb|FAM14217-p1-1.1_000722 754252.PFREUD_20050 1.1e-275 955.3 Propionibacteriales mtr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657 1.8.1.15,1.8.1.4 ko:K00382,ko:K17883 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GNSR@201174,4DPYH@85009,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gnl|extdb|FAM14217-p1-1.1_000724 754252.PFREUD_20030 0.0 1126.7 Bacteria arsA 3.6.3.16 ko:K01551 ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 Bacteria COG0003@1,COG0003@2 NA|NA|NA P Pfam Anion-transporting ATPase gnl|extdb|FAM14217-p1-1.1_000730 754252.PFREUD_19960 1.1e-162 579.3 Propionibacteriales pstC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0009314,GO:0009628,GO:0010921,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iAF987.Gmet_2702,ic_1306.c4652 Bacteria 2GJDA@201174,4DNZF@85009,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane gnl|extdb|FAM14217-p1-1.1_000750 754252.PFREUD_19720 4.5e-82 310.8 Propionibacteriales Bacteria 2BM8T@1,2IG06@201174,32FSI@2,4DR8K@85009 NA|NA|NA S tRNA adenosine gnl|extdb|FAM14217-p1-1.1_000751 754252.PFREUD_19710 5e-75 287.0 Propionibacteriales tadA 3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01485,ko:K01563,ko:K04075,ko:K11991 ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2IM3Z@201174,4DV8A@85009,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) gnl|extdb|FAM14217-p1-1.1_000766 754252.PFREUD_19580 4.5e-223 780.4 Propionibacteriales pstP 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 2GJ3M@201174,4DNAN@85009,COG0631@1,COG0631@2 NA|NA|NA T Serine/threonine phosphatases, family 2C, catalytic domain gnl|extdb|FAM14217-p1-1.1_000780 754252.PFREUD_19490 0.0 1469.9 Propionibacteriales pacS GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2GIRF@201174,4DPNE@85009,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase gnl|extdb|FAM14217-p1-1.1_000790 754252.PFREUD_19390 2.3e-175 621.3 Propionibacteriales ykuE ko:K07098 ko00000 Bacteria 2GJHT@201174,4DNBM@85009,COG1408@1,COG1408@2 NA|NA|NA S Calcineurin-like phosphoesterase gnl|extdb|FAM14217-p1-1.1_000796 1122622.ATWJ01000008_gene2694 1.2e-42 179.5 Intrasporangiaceae ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567 ko00000,ko01000,ko03400 Bacteria 2IHXW@201174,4FH29@85021,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated gnl|extdb|FAM14217-p1-1.1_000798 754252.PFREUD_19320 3.4e-115 421.0 Actinobacteria yhhQ ko:K09125 ko00000 Bacteria 2IFDB@201174,COG1738@1,COG1738@2 NA|NA|NA S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage gnl|extdb|FAM14217-p1-1.1_000810 754252.PFREUD_19190 3.1e-116 424.9 Propionibacteriales ko:K03744 ko00000 Bacteria 2GPS4@201174,4DR1W@85009,COG1704@1,COG1704@2 NA|NA|NA S LemA family gnl|extdb|FAM14217-p1-1.1_000811 754252.PFREUD_19180 1.2e-123 449.1 Propionibacteriales dedA ko:K03975 ko00000 Bacteria 2GKGR@201174,4DQX9@85009,COG0586@1,COG0586@2 NA|NA|NA I SNARE associated Golgi protein gnl|extdb|FAM14217-p1-1.1_000812 754252.PFREUD_19170 1.8e-138 498.4 Propionibacteriales spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GM1A@201174,4DN90@85009,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family gnl|extdb|FAM14217-p1-1.1_000829 754252.PFREUD_19000 5.5e-101 373.6 Propionibacteriales lysE GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 ko:K06895 ko00000,ko02000 2.A.75.1 Bacteria 2IHQ2@201174,4DQJE@85009,COG1279@1,COG1279@2 NA|NA|NA S LysE type translocator gnl|extdb|FAM14217-p1-1.1_000833 754252.PFREUD_18960 2e-158 565.1 Propionibacteriales hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01749,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iHN637.CLJU_RS15760,iPC815.YPO3849 Bacteria 2GMWI@201174,4DN1M@85009,COG0181@1,COG0181@2 NA|NA|NA H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps gnl|extdb|FAM14217-p1-1.1_000834 754252.PFREUD_18950 1.2e-280 971.8 Propionibacteriales hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0016 Bacteria 2GMY6@201174,4DP2Q@85009,COG0407@1,COG0407@2 NA|NA|NA H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III gnl|extdb|FAM14217-p1-1.1_000840 754252.PFREUD_18890 8.9e-125 453.0 Propionibacteriales Bacteria 2GJXV@201174,4DWPP@85009,COG1309@1,COG1309@2 NA|NA|NA K Bacterial transcriptional repressor C-terminal gnl|extdb|FAM14217-p1-1.1_000850 754252.PFREUD_18790 2.6e-197 694.5 Propionibacteriales senX3 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 ko:K07636,ko:K07768,ko:K11383 ko02020,map02020 M00434,M00443,M00505 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GJY7@201174,4DP15@85009,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM14217-p1-1.1_000854 754252.PFREUD_18750 3.7e-82 310.8 Propionibacteriales ispF GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.1.1.228,2.7.7.60,4.6.1.12 ko:K00554,ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05633,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iNJ661.Rv3581c Bacteria 2II8H@201174,4DQIJ@85009,COG0245@1,COG0245@2 NA|NA|NA I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) gnl|extdb|FAM14217-p1-1.1_000861 754252.PFREUD_18670 2e-151 542.0 Propionibacteriales ko:K05799 ko00000,ko03000 Bacteria 2GZJA@201174,4DV1Q@85009,COG2186@1,COG2186@2 NA|NA|NA K FCD gnl|extdb|FAM14217-p1-1.1_000871 754252.PFREUD_18560 1.4e-212 745.3 Actinobacteria ko:K01436,ko:K21613 ko00000,ko01000,ko01002 Bacteria 2GK05@201174,COG1473@1,COG1473@2 NA|NA|NA M amidohydrolase gnl|extdb|FAM14217-p1-1.1_000876 754252.PFREUD_18510 0.0 1301.6 Propionibacteriales ko:K06994 ko00000 Bacteria 2GJ5A@201174,4DNJP@85009,COG2409@1,COG2409@2 NA|NA|NA S MMPL family gnl|extdb|FAM14217-p1-1.1_000886 754252.PFREUD_18270 2.9e-127 461.1 Actinobacteria ko:K11045 ko00000,ko02042 Bacteria 2GQDQ@201174,COG1404@1,COG1404@2,COG5492@1,COG5492@2 NA|NA|NA O S-layer domain protein gnl|extdb|FAM14217-p1-1.1_000888 754252.PFREUD_18270 5.4e-65 253.8 Actinobacteria ko:K11045 ko00000,ko02042 Bacteria 2GQDQ@201174,COG1404@1,COG1404@2,COG5492@1,COG5492@2 NA|NA|NA O S-layer domain protein gnl|extdb|FAM14217-p1-1.1_000907 754252.PFREUD_18050 3.4e-71 274.2 Propionibacteriales mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 2IQDN@201174,4DRP7@85009,COG1970@1,COG1970@2 NA|NA|NA M Large-conductance mechanosensitive channel, MscL gnl|extdb|FAM14217-p1-1.1_000909 754252.PFREUD_18020 7.6e-33 146.7 Actinobacteria fmdB Bacteria 2IQHE@201174,COG2331@1,COG2331@2 NA|NA|NA S Regulatory protein, FmdB family gnl|extdb|FAM14217-p1-1.1_000918 754252.PFREUD_17920 0.0 1514.2 Propionibacteriales clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2GJ73@201174,4DN44@85009,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE gnl|extdb|FAM14217-p1-1.1_000923 754252.PFREUD_17860 2.5e-149 535.0 Actinobacteria degP ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJ96@201174,COG0265@1,COG0265@2 NA|NA|NA O Peptidase s1 and s6 chymotrypsin hap gnl|extdb|FAM14217-p1-1.1_000930 1089455.MOPEL_021_00660 1.1e-49 203.0 Dermatophilaceae Bacteria 2EJS5@1,2GY44@201174,33DGX@2,4F7DW@85018 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_000938 754252.PFREUD_17690 2.6e-68 264.6 Propionibacteriales Bacteria 2IFEY@201174,4DVR8@85009,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM14217-p1-1.1_000944 754252.PFREUD_17610 9.3e-261 905.6 Propionibacteriales gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKXG@201174,4DP86@85009,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family gnl|extdb|FAM14217-p1-1.1_000946 754252.PFREUD_17590 7.3e-62 243.0 Bacteria crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity gnl|extdb|FAM14217-p1-1.1_000953 754252.PFREUD_17510 1.5e-294 1018.1 Propionibacteriales pmt 2.4.1.109 ko:K00728 ko00514,ko00515,ko01100,map00514,map00515,map01100 R04072,R07620,R11399 RC00005,RC00059,RC00397 ko00000,ko00001,ko01000,ko01003 GT39 Bacteria 2I2H1@201174,4DP3Z@85009,COG1928@1,COG1928@2 NA|NA|NA O C-terminal four TMM region of protein-O-mannosyltransferase gnl|extdb|FAM14217-p1-1.1_000991 754252.PFREUD_17100 2.8e-119 434.5 Propionibacteriales msrA 1.8.4.11 ko:K07304 ko00000,ko01000 Bacteria 2GJ1S@201174,4DQ8G@85009,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine gnl|extdb|FAM14217-p1-1.1_000999 754252.PFREUD_17030 8.9e-92 342.8 Propionibacteriales yyaL ko:K06888 ko00000 Bacteria 2IE03@201174,4DWN1@85009,COG1331@1,COG1331@2,COG4405@1,COG4405@2 NA|NA|NA O Protein of unknown function, DUF255 gnl|extdb|FAM14217-p1-1.1_001002 754252.PFREUD_17000 2.4e-115 421.4 Propionibacteriales yplQ ko:K11068 ko00000,ko02042 Bacteria 2GJGQ@201174,4DQ8R@85009,COG1272@1,COG1272@2 NA|NA|NA S Haemolysin-III related gnl|extdb|FAM14217-p1-1.1_001015 754252.PFREUD_16790 5.1e-173 613.6 Propionibacteriales yybE Bacteria 2GTX3@201174,4DQK8@85009,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain gnl|extdb|FAM14217-p1-1.1_001016 754252.PFREUD_16780 2.1e-198 698.4 Propionibacteriales ynfM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08224 ko00000,ko02000 2.A.1.36 Bacteria 2GMWE@201174,4DTEB@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_001032 754252.PFREUD_16540 2.8e-202 711.1 Propionibacteriales moeB 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 R07459,R07461 RC00043 ko00000,ko00001,ko01000 Bacteria 2GJB6@201174,4DNCG@85009,COG0476@1,COG0476@2 NA|NA|NA H ThiF family gnl|extdb|FAM14217-p1-1.1_001040 754252.PFREUD_16460 2.8e-122 444.5 Propionibacteriales pth_2 3.1.1.29 ko:K04794 ko00000,ko01000,ko03012 Bacteria 2HEY8@201174,4DRVA@85009,COG1990@1,COG1990@2 NA|NA|NA S Peptidyl-tRNA hydrolase gnl|extdb|FAM14217-p1-1.1_001049 754252.PFREUD_16390 1.1e-220 772.3 Actinobacteria Bacteria 2GK05@201174,COG1473@1,COG1473@2 NA|NA|NA M amidohydrolase gnl|extdb|FAM14217-p1-1.1_001051 754252.PFREUD_16370 8.3e-90 336.3 Propionibacteriales yncA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 2IHSY@201174,4DS6A@85009,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain gnl|extdb|FAM14217-p1-1.1_001065 754252.PFREUD_16230 2.1e-131 474.9 Propionibacteriales fmt2 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2GKJH@201174,4DPM7@85009,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family gnl|extdb|FAM14217-p1-1.1_001071 754252.PFREUD_16170 5.5e-101 373.6 Propionibacteriales safC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 2GPEV@201174,4DNEI@85009,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase gnl|extdb|FAM14217-p1-1.1_001076 754252.PFREUD_16120 2.4e-189 668.3 Propionibacteriales mgtE Bacteria 2GMMK@201174,4DPA3@85009,COG2239@1,COG2239@2 NA|NA|NA P MgtE intracellular N domain gnl|extdb|FAM14217-p1-1.1_001083 754252.PFREUD_16060 1.3e-159 568.9 Propionibacteriales map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2GKIZ@201174,4DN75@85009,COG0024@1,COG0024@2 NA|NA|NA J Methionine aminopeptidase gnl|extdb|FAM14217-p1-1.1_001091 754252.PFREUD_15990 7.9e-97 359.8 Actinobacteria tetR Bacteria 2HAGC@201174,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_001093 754252.PFREUD_15970 1.6e-287 994.6 Propionibacteriales glnA GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GMN1@201174,4DNAS@85009,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase gnl|extdb|FAM14217-p1-1.1_001117 754252.PFREUD_15720 7.6e-263 912.5 Propionibacteriales aroH 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJBX@201174,4DNES@85009,COG3200@1,COG3200@2 NA|NA|NA E Belongs to the class-II DAHP synthase family gnl|extdb|FAM14217-p1-1.1_001121 754252.PFREUD_15680 1.8e-195 688.3 Propionibacteriales idsA 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2GJEK@201174,4DNU8@85009,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family gnl|extdb|FAM14217-p1-1.1_001122 754252.PFREUD_15670 6.8e-178 629.8 Propionibacteriales metF GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJTN@201174,4DPM1@85009,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase gnl|extdb|FAM14217-p1-1.1_001123 754252.PFREUD_15660 0.0 1365.9 Propionibacteriales Bacteria 2GK30@201174,4DPXT@85009,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase gnl|extdb|FAM14217-p1-1.1_001125 754252.PFREUD_15640 0.0 2352.4 Actinobacteria dnaE2 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ1P@201174,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase gnl|extdb|FAM14217-p1-1.1_001126 754252.PFREUD_15620 6.5e-229 799.7 Propionibacteriales dinB 2.7.7.7 ko:K02346,ko:K03502 ko00000,ko01000,ko03400 Bacteria 2GKBI@201174,4DP99@85009,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII gnl|extdb|FAM14217-p1-1.1_001129 754252.PFREUD_15580 4.8e-174 617.1 Propionibacteriales rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 2GJGK@201174,4DPXU@85009,COG0275@1,COG0275@2 NA|NA|NA M Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA gnl|extdb|FAM14217-p1-1.1_001131 754252.PFREUD_15560 0.0 1140.2 Propionibacteriales ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2GKHH@201174,4DNVU@85009,COG0768@1,COG0768@2 NA|NA|NA M Cell division protein FtsI penicillin-binding protein gnl|extdb|FAM14217-p1-1.1_001132 754252.PFREUD_15550 2.2e-301 1040.8 Propionibacteriales murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2158c Bacteria 2GIS2@201174,4DN64@85009,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan gnl|extdb|FAM14217-p1-1.1_001137 754252.PFREUD_15500 4.1e-198 697.2 Propionibacteriales murG 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232 Bacteria 2GJEM@201174,4DN0T@85009,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) gnl|extdb|FAM14217-p1-1.1_001143 754252.PFREUD_15440 1.4e-30 138.3 Bacteria yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria COG0762@1,COG0762@2 NA|NA|NA D integral membrane protein gnl|extdb|FAM14217-p1-1.1_001146 754252.PFREUD_15410 2.7e-94 351.3 Actinobacteria lspA GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKRX@201174,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins gnl|extdb|FAM14217-p1-1.1_001168 754252.PFREUD_15190 2.2e-162 578.2 Propionibacteriales rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 2GMWB@201174,4DPVQ@85009,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities gnl|extdb|FAM14217-p1-1.1_001175 754252.PFREUD_15130 4.6e-188 663.7 Propionibacteriales gap 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJK4@201174,4DNQ8@85009,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gnl|extdb|FAM14217-p1-1.1_001178 754252.PFREUD_15100 1.4e-34 151.8 Propionibacteriales secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GR31@201174,4DS3V@85009,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase SecG subunit gnl|extdb|FAM14217-p1-1.1_001182 754252.PFREUD_15060 2.7e-293 1013.8 Propionibacteriales zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 2GISI@201174,4DNXH@85009,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone gnl|extdb|FAM14217-p1-1.1_001189 754252.PFREUD_14990 5.4e-141 506.9 Propionibacteriales sufR Bacteria 2GN8W@201174,4DQCB@85009,COG2345@1,COG2345@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM14217-p1-1.1_001197 754252.PFREUD_14910 1.1e-293 1015.4 Propionibacteriales ybiT Bacteria 2GKQ4@201174,4DPPB@85009,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter gnl|extdb|FAM14217-p1-1.1_001200 754252.PFREUD_14870 7.3e-124 449.9 Propionibacteriales Bacteria 2GK6C@201174,4DPI8@85009,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM14217-p1-1.1_001203 754252.PFREUD_14840 1.4e-144 518.8 Propionibacteriales modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028,ko:K05776 ko02010,map02010 M00189,M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 2GIXX@201174,4DNDT@85009,COG1119@1,COG1119@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_001204 754252.PFREUD_14830 2.5e-172 611.3 Propionibacteriales ko:K14347 ko00000,ko02000,ko04147 2.A.93.1 Bacteria 2GJQU@201174,4DT11@85009,COG0385@1,COG0385@2 NA|NA|NA S SBF-like CPA transporter family (DUF4137) gnl|extdb|FAM14217-p1-1.1_001220 754252.PFREUD_14730 1.5e-216 758.4 Propionibacteriales rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2GJ48@201174,4DPW3@85009,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs gnl|extdb|FAM14217-p1-1.1_001222 754252.PFREUD_14710 5.2e-212 743.4 Propionibacteriales ispG GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS06430,iJN678.gcpE Bacteria 2GK2S@201174,4DP7G@85009,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate gnl|extdb|FAM14217-p1-1.1_001228 1171373.PACID_21840 5.3e-12 76.6 Bacteria ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria COG2740@1,COG2740@2 NA|NA|NA K Nucleic-acid-binding protein implicated in transcription termination gnl|extdb|FAM14217-p1-1.1_001242 754252.PFREUD_14510 0.0 1381.3 Propionibacteriales recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKA3@201174,4DNNB@85009,COG1200@1,COG1200@2 NA|NA|NA L ATP-dependent DNA helicase RecG gnl|extdb|FAM14217-p1-1.1_001250 754252.PFREUD_14430 3.2e-101 374.4 Actinobacteria MA20_09515 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 2IQYV@201174,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein gnl|extdb|FAM14217-p1-1.1_001259 754252.PFREUD_14340 9.1e-138 496.1 Propionibacteriales trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GJ1G@201174,4DNVI@85009,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family gnl|extdb|FAM14217-p1-1.1_001266 754252.PFREUD_14270 2.6e-109 401.4 Propionibacteriales rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFN@201174,4DPWD@85009,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids gnl|extdb|FAM14217-p1-1.1_001279 754252.PFREUD_14140 1e-187 662.5 Propionibacteriales Bacteria 2GMNA@201174,4DPF5@85009,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM14217-p1-1.1_001312 754252.PFREUD_13660 3.9e-264 917.1 Propionibacteriales recN GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 2GIVG@201174,4DN95@85009,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA gnl|extdb|FAM14217-p1-1.1_001314 754252.PFREUD_13640 4.3e-103 380.6 Propionibacteriales nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 2GNW6@201174,4DR6U@85009,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain gnl|extdb|FAM14217-p1-1.1_001319 754252.PFREUD_13590 2.3e-114 418.3 Propionibacteriales scpB ko:K06024 ko00000,ko03036 Bacteria 2GISY@201174,4DQ4Q@85009,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves gnl|extdb|FAM14217-p1-1.1_001321 754252.PFREUD_13570 1.6e-85 322.4 Bacteria fkbB 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase gnl|extdb|FAM14217-p1-1.1_001327 754252.PFREUD_13510 9.1e-133 479.6 Propionibacteriales tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2GJK8@201174,4DQFM@85009,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides gnl|extdb|FAM14217-p1-1.1_001332 754252.PFREUD_13460 0.0 1776.9 Propionibacteriales helY GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K03727 ko00000,ko01000 Bacteria 2GJEX@201174,4DN1B@85009,COG4581@1,COG4581@2 NA|NA|NA L DSHCT gnl|extdb|FAM14217-p1-1.1_001360 754252.PFREUD_13180 1.8e-75 288.5 Propionibacteriales cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 2IQ8T@201174,4DS1E@85009,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family gnl|extdb|FAM14217-p1-1.1_001372 754252.PFREUD_13050 0.0 1302.7 Propionibacteriales dinG GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0070035,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GKT8@201174,4DN8C@85009,COG1199@1,COG1199@2 NA|NA|NA KL HELICc2 gnl|extdb|FAM14217-p1-1.1_001378 754252.PFREUD_12990 0.0 1093.2 Actinobacteria glpA GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 iSDY_1059.SDY_2436 Bacteria 2GJKN@201174,COG0578@1,COG0578@2 NA|NA|NA C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family gnl|extdb|FAM14217-p1-1.1_001392 754252.PFREUD_12820 0.0 1324.7 Propionibacteriales gyrB2 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GM1E@201174,4DN70@85009,COG0187@1,COG0187@2 NA|NA|NA L TopoisomeraseII gnl|extdb|FAM14217-p1-1.1_001396 754252.PFREUD_12780 1.9e-109 401.7 Propionibacteriales Bacteria 29850@1,2GKR1@201174,2ZVAX@2,4DQC6@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001399 754252.PFREUD_12750 2.3e-47 194.5 Propionibacteriales Bacteria 2ATJW@1,2I810@201174,32RNQ@2,4DR4Y@85009 NA|NA|NA S Domain of unknown function (DUF4193) gnl|extdb|FAM14217-p1-1.1_001402 754252.PFREUD_12720 6.5e-60 236.5 Bacteria 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria COG1200@1,COG1200@2 NA|NA|NA L ATP-dependent DNA helicase activity gnl|extdb|FAM14217-p1-1.1_001404 754252.PFREUD_12700 3.9e-116 424.1 Propionibacteriales ceoB ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2GK4N@201174,4DNXX@85009,COG0569@1,COG0569@2 NA|NA|NA P TrkA-N domain gnl|extdb|FAM14217-p1-1.1_001406 754252.PFREUD_12680 2.7e-224 784.3 Propionibacteriales trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 2GIR3@201174,4DN2V@85009,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family gnl|extdb|FAM14217-p1-1.1_001417 754252.PFREUD_12550 1.2e-246 858.6 Propionibacteriales rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 2GKNM@201174,4DNGR@85009,COG0349@1,COG0349@2 NA|NA|NA J 3'-5' exonuclease gnl|extdb|FAM14217-p1-1.1_001427 754252.PFREUD_12440 0.0 1368.2 Propionibacteriales thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GKTC@201174,4DN38@85009,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) gnl|extdb|FAM14217-p1-1.1_001432 754252.PFREUD_12390 1.2e-106 392.5 Propionibacteriales pgsA GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GM3F@201174,4DQ8M@85009,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family gnl|extdb|FAM14217-p1-1.1_001433 754252.PFREUD_12380 2.5e-77 294.7 Propionibacteriales GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GMS5@201174,4DR0G@85009,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) gnl|extdb|FAM14217-p1-1.1_001443 754252.PFREUD_12270 0.0 1090.9 Propionibacteriales yhgE ko:K01421 ko00000 Bacteria 2GKEM@201174,4DQ2G@85009,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein gnl|extdb|FAM14217-p1-1.1_001453 754252.PFREUD_12170 1.3e-270 938.3 Propionibacteriales otsA GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K16055 ko00500,ko01100,map00500,map01100 R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT20 Bacteria 2GMX7@201174,4DNDY@85009,COG0380@1,COG0380@2 NA|NA|NA G Glycosyltransferase family 20 gnl|extdb|FAM14217-p1-1.1_001456 1033810.HLPCO_001631 3.2e-15 87.0 unclassified Bacteria Bacteria 2NRTY@2323,COG2314@1,COG2314@2 NA|NA|NA S TM2 domain gnl|extdb|FAM14217-p1-1.1_001478 754252.PFREUD_11920 4.9e-63 246.9 Propionibacteriales hisI GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1606 Bacteria 2IKKU@201174,4DR51@85009,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP gnl|extdb|FAM14217-p1-1.1_001479 754252.PFREUD_11910 7.4e-291 1005.7 Propionibacteriales trpE 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJT@201174,4DQ56@85009,COG0147@1,COG0147@2 NA|NA|NA E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia gnl|extdb|FAM14217-p1-1.1_001548 754252.PFREUD_11190 4.4e-68 263.8 Actinobacteria Bacteria 2B48T@1,2GY61@201174,31X00@2 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001560 754252.PFREUD_11070 9.6e-222 775.8 Propionibacteriales Bacteria 2I081@201174,4DW6B@85009,COG0582@1,COG0582@2 NA|NA|NA L viral genome integration into host DNA gnl|extdb|FAM14217-p1-1.1_001559 754252.PFREUD_11080 1e-29 135.2 Actinobacteria Bacteria 2B3VH@1,2GT4B@201174,31WJD@2 NA|NA|NA S Helix-turn-helix domain gnl|extdb|FAM14217-p1-1.1_001563 754252.PFREUD_11040 1.4e-249 868.6 Actinobacteria Bacteria 2GIUM@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator superfamily gnl|extdb|FAM14217-p1-1.1_001573 754252.PFREUD_10930 1.5e-135 488.8 Propionibacteriales glpQ2 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2GJ5W@201174,4DQB5@85009,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase gnl|extdb|FAM14217-p1-1.1_001589 754252.PFREUD_10770 9.8e-280 968.8 Propionibacteriales gatB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJJH@201174,4DNB4@85009,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gnl|extdb|FAM14217-p1-1.1_001595 754252.PFREUD_10710 3.1e-206 724.2 Propionibacteriales mnmA 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 2GIUQ@201174,4DPXG@85009,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 gnl|extdb|FAM14217-p1-1.1_001600 754252.PFREUD_10660 0.0 1370.9 Propionibacteriales glgE 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 R09994 ko00000,ko00001,ko01000 GH13 Bacteria 2GJKR@201174,4DMZD@85009,COG0366@1,COG0366@2 NA|NA|NA G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB gnl|extdb|FAM14217-p1-1.1_001601 754252.PFREUD_10650 0.0 1221.1 Propionibacteriales treS 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 GH13 Bacteria 2GIV1@201174,4DNMJ@85009,COG0366@1,COG0366@2 NA|NA|NA G Trehalose synthase gnl|extdb|FAM14217-p1-1.1_001603 754252.PFREUD_10630 0.0 1369.8 Propionibacteriales glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 2GJ5C@201174,4DPZS@85009,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position gnl|extdb|FAM14217-p1-1.1_001614 754252.PFREUD_10520 6e-199 699.9 Propionibacteriales lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 2GJV5@201174,4DP41@85009,COG0095@1,COG0095@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family gnl|extdb|FAM14217-p1-1.1_001623 754252.PFREUD_10430 2.8e-148 531.2 Propionibacteriales atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 2H3PR@201174,4DPUV@85009,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane gnl|extdb|FAM14217-p1-1.1_001627 754252.PFREUD_10380 4.9e-127 460.7 Propionibacteriales ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2GK2X@201174,4DQKX@85009,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine gnl|extdb|FAM14217-p1-1.1_001628 754252.PFREUD_10370 1.7e-159 568.5 Propionibacteriales prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2GMH1@201174,4DP23@85009,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif gnl|extdb|FAM14217-p1-1.1_001646 754252.PFREUD_10200 1.9e-101 375.2 Propionibacteriales sigH GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 ko:K03088 ko00000,ko03021 Bacteria 2GJ02@201174,4DMYC@85009,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily gnl|extdb|FAM14217-p1-1.1_001657 754252.PFREUD_10070 7.5e-138 496.5 Propionibacteriales sapF ko:K02032,ko:K19230 ko01503,ko02010,ko02024,map01503,map02010,map02024 M00239,M00739 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.5 Bacteria 2H4BW@201174,4DX37@85009,COG4608@1,COG4608@2 NA|NA|NA E ATPases associated with a variety of cellular activities gnl|extdb|FAM14217-p1-1.1_001666 754252.PFREUD_09980 1.8e-231 808.1 Actinobacteria ko:K07263 ko00000,ko01000,ko01002 Bacteria 2GJZ3@201174,COG0612@1,COG0612@2 NA|NA|NA S Belongs to the peptidase M16 family gnl|extdb|FAM14217-p1-1.1_001669 754252.PFREUD_09950 5.3e-101 373.6 Propionibacteriales Bacteria 2DA1Q@1,2GKR3@201174,32TUF@2,4DRDD@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001671 754252.PFREUD_09920 5.2e-259 899.8 Propionibacteriales Bacteria 2GJ9K@201174,4DN9A@85009,COG5282@1,COG5282@2 NA|NA|NA S Zincin-like metallopeptidase gnl|extdb|FAM14217-p1-1.1_001675 754252.PFREUD_09880 0.0 1378.6 Propionibacteriales uvrD2 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKRW@201174,4DNWV@85009,COG0210@1,COG0210@2 NA|NA|NA L HRDC domain gnl|extdb|FAM14217-p1-1.1_001678 754252.PFREUD_09840 0.0 1190.3 Propionibacteriales recD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJRK@201174,4DWT0@85009,COG0507@1,COG0507@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD gnl|extdb|FAM14217-p1-1.1_001693 754252.PFREUD_09690 0.0 1815.8 Propionibacteriales secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GIRT@201174,4DPEU@85009,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane gnl|extdb|FAM14217-p1-1.1_001703 754252.PFREUD_09600 2e-152 545.0 Propionibacteriales ftsX GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJMA@201174,4DQWR@85009,COG2177@1,COG2177@2 NA|NA|NA D Part of the ABC transporter FtsEX involved in cellular division gnl|extdb|FAM14217-p1-1.1_001710 754252.PFREUD_09520 1.2e-151 542.3 Actinobacteria Bacteria 2GP6F@201174,COG0388@1,COG0388@2 NA|NA|NA S Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates gnl|extdb|FAM14217-p1-1.1_001733 754252.PFREUD_09290 1.1e-119 436.0 Propionibacteriales ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 2GMHX@201174,4DSGT@85009,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) gnl|extdb|FAM14217-p1-1.1_001735 754252.PFREUD_09270 1.1e-219 768.8 Propionibacteriales dus Bacteria 2GJ8I@201174,4DNZA@85009,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines gnl|extdb|FAM14217-p1-1.1_001737 754252.PFREUD_09250 0.0 1339.7 Propionibacteriales sdhA 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ45@201174,4DN0E@85009,COG1053@1,COG1053@2 NA|NA|NA C succinate dehydrogenase gnl|extdb|FAM14217-p1-1.1_001747 754252.PFREUD_09150 3.1e-77 294.3 Propionibacteriales zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711,ko:K09823 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 2IKS3@201174,4DQZK@85009,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family gnl|extdb|FAM14217-p1-1.1_001782 754252.PFREUD_08810 8.8e-186 656.0 Propionibacteriales pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 2GNBX@201174,4DQ1B@85009,COG0596@1,COG0596@2 NA|NA|NA S Belongs to the peptidase S33 family gnl|extdb|FAM14217-p1-1.1_001812 754252.PFREUD_08490 1.2e-211 742.3 Propionibacteriales proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM8U@201174,4DNUG@85009,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate gnl|extdb|FAM14217-p1-1.1_001817 754252.PFREUD_08420 1.9e-127 461.8 Propionibacteriales Bacteria 2GIS7@201174,4DQ75@85009,COG5011@1,COG5011@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2344) gnl|extdb|FAM14217-p1-1.1_001820 754252.PFREUD_08390 7.5e-181 639.8 Propionibacteriales chaA ko:K07300 ko00000,ko02000 2.A.19 iNJ661.Rv1607 Bacteria 2GJWT@201174,4DP08@85009,COG0387@1,COG0387@2 NA|NA|NA P Sodium/calcium exchanger protein gnl|extdb|FAM14217-p1-1.1_001835 754252.PFREUD_08240 4e-110 404.1 Propionibacteriales clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK5C@201174,4DNFI@85009,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins gnl|extdb|FAM14217-p1-1.1_001841 754252.PFREUD_08180 2.1e-46 191.4 Propionibacteriales sugE ko:K11741 ko00000,ko02000 2.A.7.1 Bacteria 2IQND@201174,4DRIV@85009,COG2076@1,COG2076@2 NA|NA|NA P Small Multidrug Resistance protein gnl|extdb|FAM14217-p1-1.1_001849 754252.PFREUD_08110 5.1e-101 373.6 Propionibacteriales yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 2GJNX@201174,4DX18@85009,COG2761@1,COG2761@2 NA|NA|NA Q DSBA oxidoreductase gnl|extdb|FAM14217-p1-1.1_001856 754252.PFREUD_08040 0.0 1906.0 Propionibacteriales Bacteria 2GKI9@201174,4DN5D@85009,COG0247@1,COG0247@2,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain gnl|extdb|FAM14217-p1-1.1_001870 754252.PFREUD_07890 2.4e-124 451.4 Propionibacteriales orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GJR7@201174,4DPKU@85009,COG1949@1,COG1949@2 NA|NA|NA L 3'-to-5' exoribonuclease specific for small oligoribonucleotides gnl|extdb|FAM14217-p1-1.1_001875 754252.PFREUD_07850 1.6e-140 505.4 Propionibacteriales iphP 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 2GK28@201174,4DVE3@85009,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family gnl|extdb|FAM14217-p1-1.1_001896 754252.PFREUD_07620 1.3e-113 415.6 Actinobacteria folA 1.5.1.3 ko:K00287,ko:K18589 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 2IM1S@201174,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis gnl|extdb|FAM14217-p1-1.1_001917 754252.PFREUD_07410 1.7e-26 124.4 Bacteria ycaR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 ko:K00912,ko:K09791 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria COG2835@1,COG2835@2 NA|NA|NA EG tetraacyldisaccharide 4'-kinase activity gnl|extdb|FAM14217-p1-1.1_001927 754252.PFREUD_07310 1.7e-79 302.0 Propionibacteriales purE GO:0008150,GO:0040007 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iJN678.purE,iNJ661.Rv3275c Bacteria 2IFFD@201174,4DQ6R@85009,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) gnl|extdb|FAM14217-p1-1.1_001941 754252.PFREUD_07160 1.5e-42 178.3 Actinobacteria Bacteria 2DFKT@1,2GT3J@201174,2ZS8K@2 NA|NA|NA S Acyl-CoA carboxylase epsilon subunit gnl|extdb|FAM14217-p1-1.1_001947 754252.PFREUD_07090 6.5e-98 363.2 Propionibacteriales Bacteria 2IKSA@201174,4DR0W@85009,COG1514@1,COG1514@2 NA|NA|NA J 2'-5' RNA ligase superfamily gnl|extdb|FAM14217-p1-1.1_001957 754252.PFREUD_06980 4.7e-114 417.2 Actinobacteria yviA Bacteria 2IEEX@201174,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) gnl|extdb|FAM14217-p1-1.1_001964 754252.PFREUD_06910 7.5e-233 812.8 Propionibacteriales 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 2I4D0@201174,4DX20@85009,COG3173@1,COG3173@2 NA|NA|NA S Phosphotransferase enzyme family gnl|extdb|FAM14217-p1-1.1_001966 754252.PFREUD_06890 9.6e-118 429.5 Propionibacteriales Bacteria 2GN6R@201174,4DQH9@85009,COG1296@1,COG1296@2 NA|NA|NA E AzlC protein gnl|extdb|FAM14217-p1-1.1_001978 754252.PFREUD_06760 2.8e-155 554.7 Actinobacteria feuB ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 2GNC7@201174,COG4606@1,COG4606@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM14217-p1-1.1_001984 754252.PFREUD_06700 2.7e-174 617.8 Actinobacteria Bacteria 2HWXG@201174,COG0604@1,COG0604@2 NA|NA|NA C NADPH quinone reductase gnl|extdb|FAM14217-p1-1.1_002001 754252.PFREUD_06500 2.8e-48 197.6 Actinobacteria tyrA 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQ46@201174,COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase gnl|extdb|FAM14217-p1-1.1_002006 754252.PFREUD_06450 2.3e-184 651.4 Propionibacteriales yehZ GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 ko:K05845 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iE2348C_1286.E2348C_2278,iEC55989_1330.EC55989_2381,iECIAI39_1322.ECIAI39_0865,iECO103_1326.ECO103_2607,iECSE_1348.ECSE_2399 Bacteria 2GJWY@201174,4DU0Q@85009,COG1732@1,COG1732@2 NA|NA|NA M Substrate binding domain of ABC-type glycine betaine transport system gnl|extdb|FAM14217-p1-1.1_002018 754252.PFREUD_06330 1.2e-140 505.8 Propionibacteriales ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 2IKV2@201174,4DPK9@85009,COG0802@1,COG0802@2 NA|NA|NA K Threonylcarbamoyl adenosine biosynthesis protein TsaE gnl|extdb|FAM14217-p1-1.1_002019 754252.PFREUD_06320 9.4e-265 919.1 Propionibacteriales deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4DNT3@85009,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase gnl|extdb|FAM14217-p1-1.1_002029 754252.PFREUD_06220 3.4e-59 234.2 Propionibacteriales yccF Bacteria 2IKS5@201174,4DRE0@85009,COG3304@1,COG3304@2 NA|NA|NA S Inner membrane component domain gnl|extdb|FAM14217-p1-1.1_002030 754252.PFREUD_06210 8.4e-156 556.2 Propionibacteriales trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 2GJ8R@201174,4DNDX@85009,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA gnl|extdb|FAM14217-p1-1.1_002032 754252.PFREUD_06190 5.8e-114 416.8 Propionibacteriales rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2IFG7@201174,4DNX6@85009,COG2813@1,COG2813@2 NA|NA|NA J Ribosomal protein L11 methyltransferase (PrmA) gnl|extdb|FAM14217-p1-1.1_002036 754252.PFREUD_06140 3.9e-142 510.8 Propionibacteriales ko:K16784,ko:K16785,ko:K16786,ko:K16787,ko:K16927 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GMK1@201174,4DQPM@85009,COG1122@1,COG1122@2 NA|NA|NA P ECF transporter, substrate-specific component gnl|extdb|FAM14217-p1-1.1_002039 754252.PFREUD_06120 3.8e-154 550.8 Actinobacteria natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter gnl|extdb|FAM14217-p1-1.1_002068 754252.PFREUD_05830 1.3e-110 405.6 Propionibacteriales rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW7@201174,4DNUQ@85009,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits gnl|extdb|FAM14217-p1-1.1_002101 754252.PFREUD_05510 1.3e-76 292.4 Propionibacteriales secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GQFP@201174,4DSA3@85009,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation gnl|extdb|FAM14217-p1-1.1_002111 754252.PFREUD_05410 5.5e-106 390.2 Actinobacteria ahpC GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM74@201174,COG0450@1,COG0450@2 NA|NA|NA O alkyl hydroperoxide reductase gnl|extdb|FAM14217-p1-1.1_002122 754252.PFREUD_05300 7.3e-164 583.2 Propionibacteriales hepS GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 R09247 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 2GMB4@201174,4DNPE@85009,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family gnl|extdb|FAM14217-p1-1.1_002125 754252.PFREUD_05270 0.0 1198.7 Propionibacteriales nuoL 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 2GIT4@201174,4DP65@85009,COG1009@1,COG1009@2 NA|NA|NA CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus gnl|extdb|FAM14217-p1-1.1_002137 754252.PFREUD_05140 5.1e-256 889.8 Propionibacteriales 1.3.99.38 ko:K21401 ko00000,ko01000 Bacteria 2GKGH@201174,4DPE1@85009,COG0644@1,COG0644@2 NA|NA|NA C FAD binding domain gnl|extdb|FAM14217-p1-1.1_002145 754252.PFREUD_05060 3.1e-141 508.4 Propionibacteriales pimH Bacteria 2I2EY@201174,4DNW0@85009,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_002148 754252.PFREUD_05020 2.7e-163 581.3 Actinobacteria fieF Bacteria 2GJ8Q@201174,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family gnl|extdb|FAM14217-p1-1.1_002154 754252.PFREUD_04950 6.4e-190 669.8 Propionibacteriales 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GISW@201174,4DPID@85009,COG1063@1,COG1063@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM14217-p1-1.1_002155 754252.PFREUD_04940 1.8e-159 568.5 Actinobacteria 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 2I3AM@201174,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid gnl|extdb|FAM14217-p1-1.1_002209 754252.PFREUD_04370 4e-226 790.4 Propionibacteriales sbcD ko:K03547 ko00000,ko03400 Bacteria 2GK9R@201174,4DTJP@85009,COG0420@1,COG0420@2 NA|NA|NA L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity gnl|extdb|FAM14217-p1-1.1_002218 754252.PFREUD_04280 1.8e-81 309.3 Propionibacteriales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GIWB@201174,4DQU1@85009,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family gnl|extdb|FAM14217-p1-1.1_002225 644548.SCNU_12597 6e-11 73.9 Gordoniaceae ko:K03646 ko00000,ko02000 2.C.1.2 Bacteria 2GJ38@201174,4GB5D@85026,COG2356@1,COG2356@2,COG3064@1,COG3064@2 NA|NA|NA L Protein of unknown function (DUF1524) gnl|extdb|FAM14217-p1-1.1_002231 754252.PFREUD_04070 2e-214 751.5 Actinobacteria csbX Bacteria 2GPRH@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM14217-p1-1.1_002238 754252.PFREUD_04000 7.8e-233 812.8 Propionibacteriales purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.3.1,6.3.4.13,6.3.5.3 ko:K01945,ko:K01952,ko:K11788,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208,R04463,R04591 RC00010,RC00064,RC00090,RC00162,RC00166,RC01100,RC01160 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729,iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 2I2F5@201174,4DN4W@85009,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family gnl|extdb|FAM14217-p1-1.1_002244 754252.PFREUD_03930 4.5e-261 906.7 Propionibacteriales aguD ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 2HMMA@201174,4DNUW@85009,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM14217-p1-1.1_002273 754252.PFREUD_03620 1.7e-213 748.4 Actinobacteria 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 2I779@201174,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp domain gnl|extdb|FAM14217-p1-1.1_002288 754252.PFREUD_03380 1.5e-141 508.8 Propionibacteriales thiM 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2IC73@201174,4DUM7@85009,COG2145@1,COG2145@2 NA|NA|NA H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) gnl|extdb|FAM14217-p1-1.1_002290 754252.PFREUD_03360 3.4e-138 497.7 Propionibacteriales thiD 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKZM@201174,4DR48@85009,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase gnl|extdb|FAM14217-p1-1.1_002291 754252.PFREUD_03350 7.5e-231 806.2 Bacteria cytX ko:K03457 ko00000 2.A.39 Bacteria COG1457@1,COG1457@2 NA|NA|NA F cytosine transport gnl|extdb|FAM14217-p1-1.1_002306 754252.PFREUD_03190 2.5e-202 711.4 Propionibacteriales dinF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2GJE3@201174,4DPMZ@85009,COG0534@1,COG0534@2 NA|NA|NA V MatE gnl|extdb|FAM14217-p1-1.1_002312 754252.PFREUD_03130 1.1e-223 782.3 Actinobacteria yreE Bacteria 2HISK@201174,COG0671@1,COG0671@2 NA|NA|NA I LssY C-terminus gnl|extdb|FAM14217-p1-1.1_002333 10702.Q6VY42_9CAUD 4.4e-23 117.5 Siphoviridae GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 Viruses 4QAK6@10239,4QKKV@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidoglycan catabolic process gnl|extdb|FAM14217-p1-1.1_000074 754252.PFREUD_24470 3.7e-51 207.2 Actinobacteria ko:K07483,ko:K07497 ko00000 Bacteria 2IMAC@201174,COG2963@1,COG2963@2 NA|NA|NA L transposase activity gnl|extdb|FAM14217-p1-1.1_001278 754252.PFREUD_14150 8.2e-38 162.5 Propionibacteriales Bacteria 2EGVE@1,2HZGF@201174,33AMN@2,4DSPT@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001317 1032480.MLP_17520 4.8e-15 87.0 Propionibacteriales Bacteria 2E3JK@1,2GS0Y@201174,32YHZ@2,4DS71@85009 NA|NA|NA gnl|extdb|FAM14217-p1-1.1_001407 888439.HMPREF9240_00565 1.8e-11 75.1 Actinobacteria Bacteria 28ZZN@1,2GXJY@201174,2ZMPZ@2 NA|NA|NA # 2030 queries scanned # Total time (seconds): 1454.46838689 # Rate: 1.40 q/s