## Fri Feb  4 10:20:12 2022
## emapper-2.1.6
## /data/projects/p446_Dialact_Phoenix/6_open_genome_browser/OgbClusterServer/venv/bin/emapper.py --annotate_hits_table /data/projects/p446_Dialact_Phoenix/6_open_genome_browser/dialact/organisms/FAM1414/genomes/FAM1414-i1-1.1/3_annotation/FAM1414-i1-1.1.emapper.seed_orthologs --data_dir /dev/shm/eggnog/data -o /data/projects/p446_Dialact_Phoenix/6_open_genome_browser/dialact/organisms/FAM1414/genomes/FAM1414-i1-1.1/3_annotation/FAM1414-i1-1.1 --cpu 20
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
gnl|extdb|FAM1414-i1-1.1_000001	1203190.CAJP01000045_gene2203	1.5e-08	57.4	2BFIT@1|root,329CR@2|Bacteria,2HT3U@201174|Actinobacteria,22P9J@1653|Corynebacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
gnl|extdb|FAM1414-i1-1.1_000002	1220583.GOACH_58_01050	2.43e-10	59.7	COG1525@1|root,COG2356@1|root,COG1525@2|Bacteria,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria,4GB5D@85026|Gordoniaceae	201174|Actinobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,Excalibur
gnl|extdb|FAM1414-i1-1.1_000004	754252.PFREUD_04230	4.82e-155	436.0	2EKVV@1|root,33EJD@2|Bacteria,2GYGM@201174|Actinobacteria,4DW0T@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000005	754252.PFREUD_04240	2.93e-279	765.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cutinase
gnl|extdb|FAM1414-i1-1.1_000006	754252.PFREUD_04250	9.1e-111	318.0	COG1881@1|root,COG1881@2|Bacteria,2GMIG@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipid-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
gnl|extdb|FAM1414-i1-1.1_000007	754252.PFREUD_04260	0.0	1689.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4DPKV@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
gnl|extdb|FAM1414-i1-1.1_000008	754252.PFREUD_04270	1.04e-152	430.0	COG0800@1|root,COG0800@2|Bacteria	2|Bacteria	G	2-dehydro-3-deoxy-phosphogluconate aldolase activity	kdgA	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
gnl|extdb|FAM1414-i1-1.1_000009	754252.PFREUD_04280	3.16e-191	536.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4DQU1@85009|Propionibacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
gnl|extdb|FAM1414-i1-1.1_000010	754252.PFREUD_04290	0.0	1117.0	COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4DPRV@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
gnl|extdb|FAM1414-i1-1.1_000011	754252.PFREUD_04300	7.15e-163	458.0	COG2949@1|root,COG2949@2|Bacteria,2GWVK@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
gnl|extdb|FAM1414-i1-1.1_000012	754252.PFREUD_04310	2.96e-283	775.0	COG1680@1|root,COG1680@2|Bacteria,2GJQG@201174|Actinobacteria,4DPYC@85009|Propionibacteriales	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
gnl|extdb|FAM1414-i1-1.1_000013	754252.PFREUD_04320	0.0	1860.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4DU4S@85009|Propionibacteriales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	Arth_4141	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
gnl|extdb|FAM1414-i1-1.1_000014	754252.PFREUD_04330	4.86e-281	767.0	COG1960@1|root,COG1960@2|Bacteria,2HY9F@201174|Actinobacteria,4DTUE@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
gnl|extdb|FAM1414-i1-1.1_000015	754252.PFREUD_04340	5.63e-316	861.0	COG1075@1|root,COG1075@2|Bacteria,2GRKM@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	LCAT,PGAP1
gnl|extdb|FAM1414-i1-1.1_000016	888439.HMPREF9240_01877	9.75e-10	62.4	2ASGE@1|root,31HWJ@2|Bacteria,2HMEQ@201174|Actinobacteria,4D6VV@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000017	754252.PFREUD_04360	0.0	1862.0	COG0419@1|root,COG0419@2|Bacteria,2GKYR@201174|Actinobacteria,4DNWN@85009|Propionibacteriales	201174|Actinobacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
gnl|extdb|FAM1414-i1-1.1_000019	754252.PFREUD_04380	3.13e-259	714.0	COG1816@1|root,COG1816@2|Bacteria,2GKJP@201174|Actinobacteria,4DN6T@85009|Propionibacteriales	201174|Actinobacteria	F	adenosine deaminase	add	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
gnl|extdb|FAM1414-i1-1.1_000020	754252.PFREUD_04390	0.0	1101.0	COG0840@1|root,COG0840@2|Bacteria,2IECR@201174|Actinobacteria,4DV3X@85009|Propionibacteriales	201174|Actinobacteria	NT	Psort location	aer	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS,PAS_3
gnl|extdb|FAM1414-i1-1.1_000021	754252.PFREUD_04400	1.93e-79	236.0	292E4@1|root,2ZPYC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000024	754252.PFREUD_04430	0.0	1161.0	COG0028@1|root,COG0028@2|Bacteria,2GJ20@201174|Actinobacteria,4DQ50@85009|Propionibacteriales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	poxB	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
gnl|extdb|FAM1414-i1-1.1_000025	754252.PFREUD_04440	0.0	1124.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4DPNW@85009|Propionibacteriales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
gnl|extdb|FAM1414-i1-1.1_000026	649743.HMPREF0972_01479	7.19e-25	99.4	2EEPW@1|root,338HK@2|Bacteria,2HMSD@201174|Actinobacteria,4D7GV@85005|Actinomycetales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
gnl|extdb|FAM1414-i1-1.1_000027	754252.PFREUD_04470	1.26e-95	279.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
gnl|extdb|FAM1414-i1-1.1_000028	754252.PFREUD_04480	6.95e-159	447.0	2DBXI@1|root,2ZBQ3@2|Bacteria,2GJN1@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
gnl|extdb|FAM1414-i1-1.1_000029	754252.PFREUD_04490	2.86e-287	786.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4DND5@85009|Propionibacteriales	201174|Actinobacteria	P	Phosphate transporter family	pit3	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
gnl|extdb|FAM1414-i1-1.1_000030	1284679.HMPREF1626_02750	8.13e-07	49.3	2EITI@1|root,33CIU@2|Bacteria,2GWHZ@201174|Actinobacteria,4D6AA@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000031	754252.PFREUD_04510	1.3e-143	405.0	COG2910@1|root,COG2910@2|Bacteria,2GK2P@201174|Actinobacteria,4DS5Q@85009|Propionibacteriales	201174|Actinobacteria	S	NmrA-like family	-	-	-	ko:K07118	-	-	-	-	ko00000	-	-	-	NAD_binding_10
gnl|extdb|FAM1414-i1-1.1_000032	754252.PFREUD_04520	4.19e-140	396.0	COG2910@1|root,COG2910@2|Bacteria,2GK2P@201174|Actinobacteria,4DS5Q@85009|Propionibacteriales	201174|Actinobacteria	S	NmrA-like family	-	-	-	ko:K07118	-	-	-	-	ko00000	-	-	-	NAD_binding_10
gnl|extdb|FAM1414-i1-1.1_000033	754252.PFREUD_04530	0.0	1218.0	COG4425@1|root,COG4425@2|Bacteria,2GKB5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
gnl|extdb|FAM1414-i1-1.1_000034	754252.PFREUD_04540	0.0	1615.0	COG1643@1|root,COG1643@2|Bacteria,2GMAW@201174|Actinobacteria,4DPC5@85009|Propionibacteriales	201174|Actinobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
gnl|extdb|FAM1414-i1-1.1_000035	754252.PFREUD_04550	3.99e-183	509.0	COG0007@1|root,COG0007@2|Bacteria,2GK3B@201174|Actinobacteria,4DN4H@85009|Propionibacteriales	201174|Actinobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,NAD_binding_7,TP_methylase
gnl|extdb|FAM1414-i1-1.1_000036	754252.PFREUD_04560	9.16e-209	577.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4DN9V@85009|Propionibacteriales	201174|Actinobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000037	754252.PFREUD_04570	6.03e-177	494.0	COG0619@1|root,COG0619@2|Bacteria,2GP2M@201174|Actinobacteria,4DQAX@85009|Propionibacteriales	201174|Actinobacteria	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
gnl|extdb|FAM1414-i1-1.1_000038	754252.PFREUD_04580	4.2e-106	307.0	COG1930@1|root,COG1930@2|Bacteria,2GRJ6@201174|Actinobacteria	201174|Actinobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiN	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
gnl|extdb|FAM1414-i1-1.1_000039	754252.PFREUD_04590	9.74e-164	458.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria	201174|Actinobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
gnl|extdb|FAM1414-i1-1.1_000040	754252.PFREUD_04600	1.09e-174	488.0	COG2186@1|root,COG2186@2|Bacteria,2GKBM@201174|Actinobacteria,4DQBS@85009|Propionibacteriales	201174|Actinobacteria	K	FCD	gntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
gnl|extdb|FAM1414-i1-1.1_000041	754252.PFREUD_04610	1.98e-297	814.0	COG2610@1|root,COG2610@2|Bacteria,2GITQ@201174|Actinobacteria,4DN1V@85009|Propionibacteriales	201174|Actinobacteria	EG	GntP family permease	gnuT	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
gnl|extdb|FAM1414-i1-1.1_000042	754252.PFREUD_04620	7.12e-210	580.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4DN6Y@85009|Propionibacteriales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase, decarboxylating	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
gnl|extdb|FAM1414-i1-1.1_000043	754252.PFREUD_04630	0.0	1108.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4DP1V@85009|Propionibacteriales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
gnl|extdb|FAM1414-i1-1.1_000044	754252.PFREUD_04640	9.68e-141	399.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4DRAF@85009|Propionibacteriales	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
gnl|extdb|FAM1414-i1-1.1_000045	754252.PFREUD_04650	4.85e-260	715.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4DNFB@85009|Propionibacteriales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
gnl|extdb|FAM1414-i1-1.1_000046	754252.PFREUD_04660	2.2e-95	278.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4DVMZ@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
gnl|extdb|FAM1414-i1-1.1_000047	754252.PFREUD_04670	1.04e-220	609.0	COG2971@1|root,COG2971@2|Bacteria,2GKBF@201174|Actinobacteria,4DSI3@85009|Propionibacteriales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
gnl|extdb|FAM1414-i1-1.1_000048	754252.PFREUD_04680	0.0	1511.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DN9Q@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
gnl|extdb|FAM1414-i1-1.1_000049	754252.PFREUD_04690	0.0	895.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4DMZ8@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
gnl|extdb|FAM1414-i1-1.1_000050	1120954.ATXE01000004_gene98	6.93e-31	115.0	2DM0Y@1|root,318KY@2|Bacteria,2IMIX@201174|Actinobacteria,4DS97@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
gnl|extdb|FAM1414-i1-1.1_000051	754252.PFREUD_04720	0.0	1094.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DPF3@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
gnl|extdb|FAM1414-i1-1.1_000052	754252.PFREUD_04730	2.98e-125	358.0	COG0645@1|root,COG0645@2|Bacteria,2IKMM@201174|Actinobacteria	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
gnl|extdb|FAM1414-i1-1.1_000053	754252.PFREUD_04740	0.0	865.0	COG2848@1|root,COG2848@2|Bacteria,2HHMF@201174|Actinobacteria	201174|Actinobacteria	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
gnl|extdb|FAM1414-i1-1.1_000054	754252.PFREUD_04750	1.18e-55	173.0	COG3830@1|root,COG3830@2|Bacteria,2IKS1@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
gnl|extdb|FAM1414-i1-1.1_000055	1089453.GOSPT_007_01000	5.12e-06	55.1	COG0515@1|root,COG0515@2|Bacteria,2HXWG@201174|Actinobacteria,4GG6R@85026|Gordoniaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000057	754252.PFREUD_04780	3.26e-253	694.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4DMYH@85009|Propionibacteriales	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
gnl|extdb|FAM1414-i1-1.1_000058	754252.PFREUD_04800	2.33e-47	151.0	2EGRW@1|root,33AI2@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3073
gnl|extdb|FAM1414-i1-1.1_000059	754252.PFREUD_04810	6.03e-273	745.0	COG2267@1|root,COG2267@2|Bacteria,2GIVB@201174|Actinobacteria,4DP02@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
gnl|extdb|FAM1414-i1-1.1_000063	754252.PFREUD_04850	0.0	1013.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4DQU1@85009|Propionibacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
gnl|extdb|FAM1414-i1-1.1_000064	754252.PFREUD_04860	7.66e-182	507.0	COG0842@1|root,COG0842@2|Bacteria,2IITR@201174|Actinobacteria	201174|Actinobacteria	V	Abc-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
gnl|extdb|FAM1414-i1-1.1_000066	754252.PFREUD_04880	1.08e-80	239.0	COG1131@1|root,COG1131@2|Bacteria,2GJ84@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_000067	754252.PFREUD_04890	5.39e-155	438.0	COG1309@1|root,COG1309@2|Bacteria,2GP2Z@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
gnl|extdb|FAM1414-i1-1.1_000069	203120.LEUM_0817	2.6e-23	97.8	COG3064@1|root,COG3064@2|Bacteria,1VASR@1239|Firmicutes,4HH3I@91061|Bacilli,4AY42@81850|Leuconostocaceae	91061|Bacilli	M	Host cell surface-exposed lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp
gnl|extdb|FAM1414-i1-1.1_000070	351016.RAZWK3B_16780	3.45e-05	47.8	COG2932@1|root,COG2932@2|Bacteria,1N97M@1224|Proteobacteria,2UF88@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
gnl|extdb|FAM1414-i1-1.1_000071	158787.BSCA_3000	1.32e-05	46.2	2B5UV@1|root,31YQM@2|Bacteria,2H13Y@201174|Actinobacteria,4D1QG@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000072	1123322.KB904719_gene5113	1.18e-20	95.1	COG2197@1|root,COG2197@2|Bacteria,2GTG5@201174|Actinobacteria	201174|Actinobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000073	1206732.BAGD01000280_gene6514	1.07e-38	144.0	2CHG1@1|root,32YZS@2|Bacteria,2IRMN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000074	702450.CUW_2180	0.0002	44.3	2EGVY@1|root,33AN6@2|Bacteria,1VN7Q@1239|Firmicutes	1239|Firmicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
gnl|extdb|FAM1414-i1-1.1_000076	1489678.RDMS_01785	3.83e-13	73.9	2CBW9@1|root,34C12@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000077	1172180.KB911777_gene1924	2.37e-44	160.0	COG5377@1|root,COG5377@2|Bacteria,2ICEE@201174|Actinobacteria	201174|Actinobacteria	L	YqaJ-like viral recombinase domain	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
gnl|extdb|FAM1414-i1-1.1_000078	479433.Caci_3047	2.13e-75	239.0	COG3723@1|root,COG3723@2|Bacteria,2IA1A@201174|Actinobacteria	201174|Actinobacteria	L	RecT family	-	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	RecT
gnl|extdb|FAM1414-i1-1.1_000082	1486424.A0A023W5Q6_9CAUD	3.35e-102	304.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales	28883|Caudovirales	S	N-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000087	1125718.HMPREF1318_0889	5.4e-105	320.0	COG0270@1|root,COG0270@2|Bacteria,2I8R8@201174|Actinobacteria,4D6HQ@85005|Actinomycetales	201174|Actinobacteria	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
gnl|extdb|FAM1414-i1-1.1_000089	1437603.BMON_1155	1.51e-23	95.5	2B0RD@1|root,31T3K@2|Bacteria,2GRNW@201174|Actinobacteria,4D1J4@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	3.1.22.4	ko:K01160	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000090	1415166.NONO_c73280	2.34e-68	219.0	2EUW1@1|root,33070@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000091	47716.JOFH01000001_gene2454	6.15e-10	62.8	2C5BQ@1|root,33FPA@2|Bacteria,2IQQ0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000093	754252.PFREUD_23460	2.99e-67	209.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4DQ95@85009|Propionibacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
gnl|extdb|FAM1414-i1-1.1_000100	640132.Srot_1167	2.27e-129	393.0	COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
gnl|extdb|FAM1414-i1-1.1_000101	1449976.KALB_4961	2.82e-92	304.0	COG4695@1|root,COG4695@2|Bacteria,2I9PX@201174|Actinobacteria	201174|Actinobacteria	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
gnl|extdb|FAM1414-i1-1.1_000102	1449976.KALB_4962	1.41e-32	132.0	2B4IX@1|root,31XAZ@2|Bacteria,2GYQV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000103	1449976.KALB_4963	9.78e-64	219.0	COG4653@1|root,COG4653@2|Bacteria,2ICZP@201174|Actinobacteria,4E712@85010|Pseudonocardiales	201174|Actinobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78,Phage_capsid
gnl|extdb|FAM1414-i1-1.1_000104	1341695.BBOMB_1037	7.49e-08	57.8	2A37Y@1|root,30RPJ@2|Bacteria,2IP6J@201174|Actinobacteria,4D10A@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000105	566461.SSFG_01010	5.99e-06	49.3	2BIEU@1|root,32CM8@2|Bacteria,2GSGV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000108	1054860.KB913030_gene3920	1.48e-15	79.3	2F1JS@1|root,33UK6@2|Bacteria,2ICBZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000111	1283283.ATXA01000001_gene629	9.94e-52	200.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria	2|Bacteria	N	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
gnl|extdb|FAM1414-i1-1.1_000113	680198.SCAB_65041	1.94e-25	114.0	2DWRB@1|root,341IF@2|Bacteria,2ID68@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF5047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5047
gnl|extdb|FAM1414-i1-1.1_000115	680198.SCAB_65061	0.000646	47.4	2BFKT@1|root,329F2@2|Bacteria,2IPQZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000117	1499967.BAYZ01000197_gene3014	0.000141	46.6	2EPSZ@1|root,33HDG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000119	1123321.KB905834_gene388	2.39e-22	101.0	COG3757@1|root,COG3757@2|Bacteria,2GNZ1@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25
gnl|extdb|FAM1414-i1-1.1_000120	1125712.HMPREF1316_2355	6.33e-09	55.8	2E4T7@1|root,32ZMK@2|Bacteria,2GVRN@201174|Actinobacteria	201174|Actinobacteria	S	Putative lactococcus lactis phage r1t holin	-	-	-	-	-	-	-	-	-	-	-	-	Phage_r1t_holin
gnl|extdb|FAM1414-i1-1.1_000123	1150599.MPHLEI_19984	5.42e-05	47.0	29RHX@1|root,30CKW@2|Bacteria,2HB0P@201174|Actinobacteria,23EGS@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000124	298655.KI912267_gene7666	1.58e-52	187.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESQP@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
gnl|extdb|FAM1414-i1-1.1_000126	754252.PFREUD_04910	2.39e-93	273.0	COG0640@1|root,COG0640@2|Bacteria,2IMCT@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
gnl|extdb|FAM1414-i1-1.1_000127	754252.PFREUD_04920	0.0	1154.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54	ko:K01533,ko:K01534,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
gnl|extdb|FAM1414-i1-1.1_000128	754252.PFREUD_04930	6.95e-284	775.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4DPVC@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	aspB	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
gnl|extdb|FAM1414-i1-1.1_000130	754252.PFREUD_04950	3.23e-247	678.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DPID@85009|Propionibacteriales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
gnl|extdb|FAM1414-i1-1.1_000132	754252.PFREUD_04970	4.43e-250	687.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4DN6D@85009|Propionibacteriales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
gnl|extdb|FAM1414-i1-1.1_000134	754252.PFREUD_04990	1.77e-78	233.0	COG3861@1|root,COG3861@2|Bacteria	2|Bacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	puhA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464	-	ko:K13991	ko02020,map02020	-	-	-	ko00000,ko00001,ko00194	-	-	-	PRC,PRCH
gnl|extdb|FAM1414-i1-1.1_000135	1122994.AUFR01000005_gene830	1.86e-173	506.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
gnl|extdb|FAM1414-i1-1.1_000136	754252.PFREUD_05020	3.9e-218	603.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
gnl|extdb|FAM1414-i1-1.1_000137	754252.PFREUD_05030	1.7e-115	330.0	COG2131@1|root,COG2131@2|Bacteria,2IJ94@201174|Actinobacteria	201174|Actinobacteria	F	Deoxycytidylate deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
gnl|extdb|FAM1414-i1-1.1_000138	754252.PFREUD_05040	6.78e-82	243.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
gnl|extdb|FAM1414-i1-1.1_000140	1122994.AUFR01000005_gene826	4.74e-25	95.9	2EGDD@1|root,33A58@2|Bacteria,2HKYH@201174|Actinobacteria,4DSSA@85009|Propionibacteriales	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
gnl|extdb|FAM1414-i1-1.1_000141	754252.PFREUD_05080	1.43e-194	541.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4DNAI@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
gnl|extdb|FAM1414-i1-1.1_000142	754252.PFREUD_05090	0.0	1195.0	COG2251@1|root,COG2251@2|Bacteria,2HF5B@201174|Actinobacteria,4DWCJ@85009|Propionibacteriales	201174|Actinobacteria	V	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H_2
gnl|extdb|FAM1414-i1-1.1_000143	754252.PFREUD_05100	8.17e-168	470.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4DNP2@85009|Propionibacteriales	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
gnl|extdb|FAM1414-i1-1.1_000144	754252.PFREUD_05110	5.25e-158	443.0	COG1131@1|root,COG1131@2|Bacteria,2IJGC@201174|Actinobacteria,4DQSV@85009|Propionibacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ccmA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000146	754252.PFREUD_05130	7.25e-305	830.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4DPGF@85009|Propionibacteriales	201174|Actinobacteria	HQ	Isochorismate synthase	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
gnl|extdb|FAM1414-i1-1.1_000148	754252.PFREUD_05160	1.43e-80	239.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4DR0D@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
gnl|extdb|FAM1414-i1-1.1_000149	754252.PFREUD_05170	9.73e-137	386.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4DNIV@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
gnl|extdb|FAM1414-i1-1.1_000150	754252.PFREUD_05180	1.2e-192	533.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4DPNJ@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
gnl|extdb|FAM1414-i1-1.1_000151	754252.PFREUD_05190	0.0	919.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DPY1@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
gnl|extdb|FAM1414-i1-1.1_000152	754252.PFREUD_05200	1.63e-175	489.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4DN2R@85009|Propionibacteriales	201174|Actinobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
gnl|extdb|FAM1414-i1-1.1_000153	754252.PFREUD_05210	0.0	921.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4DPP6@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
gnl|extdb|FAM1414-i1-1.1_000154	754252.PFREUD_05220	0.0	1569.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4DNGW@85009|Propionibacteriales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
gnl|extdb|FAM1414-i1-1.1_000155	754252.PFREUD_05230	0.0	891.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4DNAD@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	NADHdh
gnl|extdb|FAM1414-i1-1.1_000156	754252.PFREUD_05240	1.01e-145	409.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4DP1W@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
gnl|extdb|FAM1414-i1-1.1_000157	754252.PFREUD_05250	1.6e-189	528.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4DPPF@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
gnl|extdb|FAM1414-i1-1.1_000158	754252.PFREUD_05260	2.53e-57	178.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4DRR0@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
gnl|extdb|FAM1414-i1-1.1_000160	754252.PFREUD_05280	0.0	970.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4DPXE@85009|Propionibacteriales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
gnl|extdb|FAM1414-i1-1.1_000161	754252.PFREUD_05290	0.0	964.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4DNIM@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
gnl|extdb|FAM1414-i1-1.1_000162	754252.PFREUD_05300	3.47e-245	674.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4DNPE@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
gnl|extdb|FAM1414-i1-1.1_000163	754252.PFREUD_05310	4.54e-114	326.0	COG3152@1|root,COG3152@2|Bacteria	2|Bacteria	L	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,DUF805
gnl|extdb|FAM1414-i1-1.1_000164	754252.PFREUD_05320	7e-254	700.0	COG3152@1|root,COG3152@2|Bacteria	2|Bacteria	L	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
gnl|extdb|FAM1414-i1-1.1_000165	754252.PFREUD_05330	0.0	1339.0	COG3590@1|root,COG3590@2|Bacteria,2GNJY@201174|Actinobacteria,4DQ4I@85009|Propionibacteriales	201174|Actinobacteria	O	Peptidase family M13	pepO	-	3.4.24.11,3.4.24.71	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
gnl|extdb|FAM1414-i1-1.1_000166	754252.PFREUD_05340	1.11e-263	721.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4DQ3H@85009|Propionibacteriales	201174|Actinobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
gnl|extdb|FAM1414-i1-1.1_000167	754252.PFREUD_05350	0.0	1237.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4DPBE@85009|Propionibacteriales	201174|Actinobacteria	C	ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
gnl|extdb|FAM1414-i1-1.1_000168	754252.PFREUD_05360	0.0	1054.0	2DBIT@1|root,2Z9GU@2|Bacteria,2GN9J@201174|Actinobacteria,4DTW6@85009|Propionibacteriales	201174|Actinobacteria	S	Carotene biosynthesis associated membrane protein	-	-	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000170	754252.PFREUD_05380	1.29e-232	639.0	COG0708@1|root,COG0708@2|Bacteria,2GKIS@201174|Actinobacteria,4DNS6@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
gnl|extdb|FAM1414-i1-1.1_000174	754252.PFREUD_05420	0.0	1096.0	COG3634@1|root,COG3634@2|Bacteria,2H4AX@201174|Actinobacteria,4DWPW@85009|Propionibacteriales	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
gnl|extdb|FAM1414-i1-1.1_000177	754252.PFREUD_05450	2.71e-35	119.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
gnl|extdb|FAM1414-i1-1.1_000178	754252.PFREUD_05460	1.13e-97	284.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4DRU6@85009|Propionibacteriales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
gnl|extdb|FAM1414-i1-1.1_000179	754252.PFREUD_05470	3.66e-98	285.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4DRH0@85009|Propionibacteriales	201174|Actinobacteria	I	MaoC like domain	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
gnl|extdb|FAM1414-i1-1.1_000180	754252.PFREUD_05480	1.32e-271	743.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4DNF7@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
gnl|extdb|FAM1414-i1-1.1_000181	28444.JODQ01000002_gene4647	3.36e-06	58.2	COG5305@1|root,COG5305@2|Bacteria,2GN7C@201174|Actinobacteria,4EJI9@85012|Streptosporangiales	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
gnl|extdb|FAM1414-i1-1.1_000184	754252.PFREUD_05520	4.31e-203	563.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4DPR5@85009|Propionibacteriales	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
gnl|extdb|FAM1414-i1-1.1_000185	754252.PFREUD_05530	4.28e-92	270.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4DQC0@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
gnl|extdb|FAM1414-i1-1.1_000186	754252.PFREUD_05540	6.34e-165	461.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4DNBG@85009|Propionibacteriales	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
gnl|extdb|FAM1414-i1-1.1_000187	754252.PFREUD_05550	1.17e-209	579.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4DPMN@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
gnl|extdb|FAM1414-i1-1.1_000188	754252.PFREUD_05560	4.81e-225	620.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4DPBB@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
gnl|extdb|FAM1414-i1-1.1_000189	754252.PFREUD_05570	1.03e-130	373.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4DQF9@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
gnl|extdb|FAM1414-i1-1.1_000190	754252.PFREUD_05580	1.16e-68	209.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4DQS8@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
gnl|extdb|FAM1414-i1-1.1_000192	754252.PFREUD_05600	0.0	2320.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4DMYN@85009|Propionibacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
gnl|extdb|FAM1414-i1-1.1_000193	754252.PFREUD_05610	0.0	2524.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4DP2S@85009|Propionibacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
gnl|extdb|FAM1414-i1-1.1_000194	754252.PFREUD_05620	4.75e-80	238.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4DQR6@85009|Propionibacteriales	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
gnl|extdb|FAM1414-i1-1.1_000195	754252.PFREUD_05630	2.22e-103	299.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4DQ8Q@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
gnl|extdb|FAM1414-i1-1.1_000196	754252.PFREUD_05640	0.0	1396.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4DNTK@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
gnl|extdb|FAM1414-i1-1.1_000197	754252.PFREUD_05650	8.91e-291	793.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4DP42@85009|Propionibacteriales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
gnl|extdb|FAM1414-i1-1.1_000198	754252.PFREUD_05660	0.0	1011.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
gnl|extdb|FAM1414-i1-1.1_000199	754252.PFREUD_05670	5.65e-131	372.0	COG1670@1|root,COG1670@2|Bacteria,2IIEK@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
gnl|extdb|FAM1414-i1-1.1_000200	754252.PFREUD_05680	0.0	977.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4DPQP@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
gnl|extdb|FAM1414-i1-1.1_000201	754252.PFREUD_05690	9.59e-212	584.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
gnl|extdb|FAM1414-i1-1.1_000202	754252.PFREUD_05700	7.35e-70	210.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4DQJR@85009|Propionibacteriales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
gnl|extdb|FAM1414-i1-1.1_000203	754252.PFREUD_05710	3.94e-154	433.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4DNWZ@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
gnl|extdb|FAM1414-i1-1.1_000204	754252.PFREUD_05720	1.55e-159	447.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4DN59@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
gnl|extdb|FAM1414-i1-1.1_000205	754252.PFREUD_05730	3.51e-68	206.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4DR9N@85009|Propionibacteriales	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
gnl|extdb|FAM1414-i1-1.1_000206	754252.PFREUD_05740	7.23e-201	556.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4DN2A@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
gnl|extdb|FAM1414-i1-1.1_000207	754252.PFREUD_05750	9.07e-64	194.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4DR2Q@85009|Propionibacteriales	201174|Actinobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
gnl|extdb|FAM1414-i1-1.1_000208	754252.PFREUD_05760	3.62e-100	291.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4DQNW@85009|Propionibacteriales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
gnl|extdb|FAM1414-i1-1.1_000209	754252.PFREUD_05770	3.63e-129	374.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4DNUB@85009|Propionibacteriales	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
gnl|extdb|FAM1414-i1-1.1_000210	754252.PFREUD_05780	5.47e-98	284.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4DQ7S@85009|Propionibacteriales	201174|Actinobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
gnl|extdb|FAM1414-i1-1.1_000211	754252.PFREUD_05790	1.29e-49	157.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4DRUK@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
gnl|extdb|FAM1414-i1-1.1_000212	754252.PFREUD_05800	6.76e-56	174.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4DRI1@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
gnl|extdb|FAM1414-i1-1.1_000213	754252.PFREUD_05810	4.06e-81	240.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4DQTB@85009|Propionibacteriales	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
gnl|extdb|FAM1414-i1-1.1_000214	754252.PFREUD_05820	2.26e-78	233.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4DRJP@85009|Propionibacteriales	201174|Actinobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
gnl|extdb|FAM1414-i1-1.1_000216	754252.PFREUD_05840	2.78e-37	125.0	COG0199@1|root,COG0199@2|Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
gnl|extdb|FAM1414-i1-1.1_000217	754252.PFREUD_05850	4.21e-91	266.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4DQQ1@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
gnl|extdb|FAM1414-i1-1.1_000218	754252.PFREUD_05860	1.62e-128	365.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4DNFZ@85009|Propionibacteriales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
gnl|extdb|FAM1414-i1-1.1_000219	754252.PFREUD_05870	9.07e-80	237.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4DR5B@85009|Propionibacteriales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
gnl|extdb|FAM1414-i1-1.1_000220	754252.PFREUD_05880	4.34e-120	346.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4DNXT@85009|Propionibacteriales	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
gnl|extdb|FAM1414-i1-1.1_000221	754252.PFREUD_05890	1.02e-34	118.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
gnl|extdb|FAM1414-i1-1.1_000222	754252.PFREUD_05900	7.03e-98	285.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4DQND@85009|Propionibacteriales	201174|Actinobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
gnl|extdb|FAM1414-i1-1.1_000223	754252.PFREUD_05910	1.14e-143	406.0	COG0431@1|root,COG0431@2|Bacteria,2IHWU@201174|Actinobacteria,4DQNQ@85009|Propionibacteriales	201174|Actinobacteria	S	FMN reductase	ssuE	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
gnl|extdb|FAM1414-i1-1.1_000224	754252.PFREUD_05920	1.1e-301	821.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4DNNU@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
gnl|extdb|FAM1414-i1-1.1_000225	754252.PFREUD_05930	0.0	1101.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4DUB4@85009|Propionibacteriales	201174|Actinobacteria	E	COG0747 ABC-type dipeptide transport system, periplasmic component	oppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
gnl|extdb|FAM1414-i1-1.1_000226	754252.PFREUD_05940	0.0	1365.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4DWGB@85009|Propionibacteriales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
gnl|extdb|FAM1414-i1-1.1_000227	754252.PFREUD_05950	3.65e-226	624.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
gnl|extdb|FAM1414-i1-1.1_000228	754252.PFREUD_05960	1.38e-230	637.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	oppB1	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_000229	754252.PFREUD_05970	2.66e-306	836.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4DN3Y@85009|Propionibacteriales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
gnl|extdb|FAM1414-i1-1.1_000230	754252.PFREUD_05980	2.75e-130	370.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4DP2T@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
gnl|extdb|FAM1414-i1-1.1_000232	1120954.ATXE01000003_gene392	9.42e-15	72.8	COG4758@1|root,COG4758@2|Bacteria,2HP3B@201174|Actinobacteria,4DSH5@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
gnl|extdb|FAM1414-i1-1.1_000233	754252.PFREUD_06010	1.14e-62	191.0	COG2350@1|root,COG2350@2|Bacteria,2GQTW@201174|Actinobacteria,4DSNY@85009|Propionibacteriales	201174|Actinobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
gnl|extdb|FAM1414-i1-1.1_000234	754252.PFREUD_06020	1.09e-46	149.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4DRMG@85009|Propionibacteriales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
gnl|extdb|FAM1414-i1-1.1_000235	754252.PFREUD_06030	5.99e-20	79.7	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
gnl|extdb|FAM1414-i1-1.1_000236	754252.PFREUD_06040	2.43e-78	233.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4DQUI@85009|Propionibacteriales	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
gnl|extdb|FAM1414-i1-1.1_000237	754252.PFREUD_06050	5.53e-87	256.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4DQ7M@85009|Propionibacteriales	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
gnl|extdb|FAM1414-i1-1.1_000238	754252.PFREUD_06060	8.82e-141	397.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4DP75@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
gnl|extdb|FAM1414-i1-1.1_000239	754252.PFREUD_06070	2.72e-238	655.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4DNW6@85009|Propionibacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
gnl|extdb|FAM1414-i1-1.1_000240	754252.PFREUD_06080	6.18e-97	286.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4DQBP@85009|Propionibacteriales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
gnl|extdb|FAM1414-i1-1.1_000241	754252.PFREUD_06090	3.8e-273	747.0	COG0438@1|root,COG0438@2|Bacteria,2GNYW@201174|Actinobacteria,4DPGM@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase Family 4	pimC	-	-	ko:K14335	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
gnl|extdb|FAM1414-i1-1.1_000242	754252.PFREUD_06100	7.93e-249	684.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4DMZZ@85009|Propionibacteriales	201174|Actinobacteria	M	G5	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
gnl|extdb|FAM1414-i1-1.1_000243	754252.PFREUD_06110	5.55e-149	418.0	COG0605@1|root,COG0605@2|Bacteria,2GJV8@201174|Actinobacteria,4DQ3N@85009|Propionibacteriales	201174|Actinobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
gnl|extdb|FAM1414-i1-1.1_000245	754252.PFREUD_06130	0.0	1008.0	2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
gnl|extdb|FAM1414-i1-1.1_000247	754252.PFREUD_06150	0.0	1028.0	COG3845@1|root,COG3845@2|Bacteria,2I2Y2@201174|Actinobacteria,4DP2H@85009|Propionibacteriales	201174|Actinobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000248	754252.PFREUD_06160	3.49e-251	691.0	COG0619@1|root,COG0619@2|Bacteria,2GKHK@201174|Actinobacteria,4DPHW@85009|Propionibacteriales	201174|Actinobacteria	P	Cobalt transport protein	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
gnl|extdb|FAM1414-i1-1.1_000249	1120954.ATXE01000003_gene432	4.86e-31	122.0	2E775@1|root,331R0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000250	754252.PFREUD_06190	6.96e-151	424.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4DNX6@85009|Propionibacteriales	201174|Actinobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
gnl|extdb|FAM1414-i1-1.1_000251	754252.PFREUD_06200	2.96e-209	578.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4DPSE@85009|Propionibacteriales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
gnl|extdb|FAM1414-i1-1.1_000252	754252.PFREUD_06210	1.12e-207	573.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4DNDX@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
gnl|extdb|FAM1414-i1-1.1_000254	754252.PFREUD_06230	0.0	1378.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4DNXI@85009|Propionibacteriales	201174|Actinobacteria	J	Elongation factor G, domain IV	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
gnl|extdb|FAM1414-i1-1.1_000255	754252.PFREUD_06240	5.57e-104	300.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4DQET@85009|Propionibacteriales	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
gnl|extdb|FAM1414-i1-1.1_000256	754252.PFREUD_06250	5.66e-112	323.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4DQN0@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
gnl|extdb|FAM1414-i1-1.1_000257	754252.PFREUD_06260	4.87e-314	857.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4DNFP@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
gnl|extdb|FAM1414-i1-1.1_000258	754252.PFREUD_06270	1.06e-257	706.0	COG1072@1|root,COG1072@2|Bacteria,2GIRR@201174|Actinobacteria,4DPFH@85009|Propionibacteriales	201174|Actinobacteria	H	pantothenate kinase activity	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
gnl|extdb|FAM1414-i1-1.1_000259	754252.PFREUD_06280	0.0	1214.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4DNBT@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
gnl|extdb|FAM1414-i1-1.1_000260	754252.PFREUD_06290	1.62e-100	292.0	COG0736@1|root,COG0736@2|Bacteria,2IQF6@201174|Actinobacteria,4DRCQ@85009|Propionibacteriales	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
gnl|extdb|FAM1414-i1-1.1_000261	754252.PFREUD_06300	0.0	905.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4DN6W@85009|Propionibacteriales	201174|Actinobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
gnl|extdb|FAM1414-i1-1.1_000262	754252.PFREUD_06310	4.82e-276	754.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4DNSP@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase Family 4	mgtA	GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12583	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
gnl|extdb|FAM1414-i1-1.1_000265	754252.PFREUD_06340	1.5e-159	447.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4DQ98@85009|Propionibacteriales	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
gnl|extdb|FAM1414-i1-1.1_000266	754252.PFREUD_06350	2.83e-121	346.0	COG0454@1|root,COG0456@2|Bacteria,2HZJQ@201174|Actinobacteria,4DRZ3@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
gnl|extdb|FAM1414-i1-1.1_000267	754252.PFREUD_06360	4.98e-250	687.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4DP6P@85009|Propionibacteriales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
gnl|extdb|FAM1414-i1-1.1_000268	754252.PFREUD_06370	0.0	1214.0	COG0778@1|root,COG2038@1|root,COG0778@2|Bacteria,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4DWZJ@85009|Propionibacteriales	201174|Actinobacteria	CH	Phosphoribosyltransferase	bluB	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT,Nitroreductase
gnl|extdb|FAM1414-i1-1.1_000269	754252.PFREUD_06380	0.0	947.0	COG3579@1|root,COG3579@2|Bacteria,2HCVR@201174|Actinobacteria,4DWUZ@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase C1-like family	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
gnl|extdb|FAM1414-i1-1.1_000270	754252.PFREUD_06390	5.2e-118	337.0	COG1051@1|root,COG1051@2|Bacteria,2INEI@201174|Actinobacteria	201174|Actinobacteria	F	NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_000272	754252.PFREUD_06410	0.0	900.0	COG2265@1|root,COG2265@2|Bacteria,2GK97@201174|Actinobacteria,4DPMI@85009|Propionibacteriales	201174|Actinobacteria	J	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_15,Methyltransf_25
gnl|extdb|FAM1414-i1-1.1_000273	754252.PFREUD_06420	1.17e-135	385.0	COG1174@1|root,COG1174@2|Bacteria,2GMQT@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter permease	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_000274	754252.PFREUD_06430	4.8e-308	841.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	proV	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
gnl|extdb|FAM1414-i1-1.1_000275	754252.PFREUD_06440	5.53e-159	447.0	COG1174@1|root,COG1174@2|Bacteria,2H9I7@201174|Actinobacteria,4DTU3@85009|Propionibacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	opuBB	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
gnl|extdb|FAM1414-i1-1.1_000276	754252.PFREUD_06450	1.04e-244	672.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DU0Q@85009|Propionibacteriales	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
gnl|extdb|FAM1414-i1-1.1_000277	754252.PFREUD_06460	6.23e-62	190.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4DR0X@85009|Propionibacteriales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
gnl|extdb|FAM1414-i1-1.1_000278	754252.PFREUD_06470	0.0	996.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNCJ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
gnl|extdb|FAM1414-i1-1.1_000279	754252.PFREUD_06480	0.0	991.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4DN68@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
gnl|extdb|FAM1414-i1-1.1_000280	754252.PFREUD_06490	5.71e-261	715.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4DN1G@85009|Propionibacteriales	201174|Actinobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
gnl|extdb|FAM1414-i1-1.1_000283	1690.BPSG_1585	3.54e-07	61.6	COG1520@1|root,COG1520@2|Bacteria,2IBDZ@201174|Actinobacteria,4CYUA@85004|Bifidobacteriales	201174|Actinobacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,zinc_ribbon_2
gnl|extdb|FAM1414-i1-1.1_000284	1449353.JQMQ01000005_gene4539	4.39e-05	53.9	2DYQ9@1|root,34ANP@2|Bacteria,2IDJX@201174|Actinobacteria,2NIIJ@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NERD
gnl|extdb|FAM1414-i1-1.1_000285	1089453.GOSPT_088_00130	6.33e-20	93.2	2B35U@1|root,31VTR@2|Bacteria,2HX5K@201174|Actinobacteria,4GDYQ@85026|Gordoniaceae	201174|Actinobacteria	S	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
gnl|extdb|FAM1414-i1-1.1_000287	754252.PFREUD_06560	5.9e-206	571.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
gnl|extdb|FAM1414-i1-1.1_000288	1121924.ATWH01000004_gene2276	7.78e-287	800.0	COG1069@1|root,COG1069@2|Bacteria,2H531@201174|Actinobacteria,4FR1B@85023|Microbacteriaceae	201174|Actinobacteria	C	FGGY family of carbohydrate kinases, N-terminal domain	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
gnl|extdb|FAM1414-i1-1.1_000289	754252.PFREUD_06590	1.34e-151	426.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,4DNAZ@85009|Propionibacteriales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
gnl|extdb|FAM1414-i1-1.1_000290	754252.PFREUD_06610	0.0	1017.0	COG2160@1|root,COG2160@2|Bacteria,2GJNB@201174|Actinobacteria,4DPD0@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
gnl|extdb|FAM1414-i1-1.1_000291	754252.PFREUD_06620	4.73e-242	665.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4DQ8P@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
gnl|extdb|FAM1414-i1-1.1_000292	754252.PFREUD_06630	7.05e-223	615.0	COG1879@1|root,COG1879@2|Bacteria,2GJ0Z@201174|Actinobacteria,4DQJY@85009|Propionibacteriales	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
gnl|extdb|FAM1414-i1-1.1_000294	754252.PFREUD_06660	8.46e-133	385.0	COG1172@1|root,COG1172@2|Bacteria,2HB45@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	ytfT	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
gnl|extdb|FAM1414-i1-1.1_000295	754252.PFREUD_06670	2.77e-228	630.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4DQ7E@85009|Propionibacteriales	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057,ko:K10440,ko:K17209	ko02010,map02010	M00212,M00221,M00592	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21	-	-	BPD_transp_2
gnl|extdb|FAM1414-i1-1.1_000296	754252.PFREUD_06680	0.0	1025.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4DPFU@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
gnl|extdb|FAM1414-i1-1.1_000297	754252.PFREUD_06690	1.49e-222	612.0	COG3878@1|root,COG3878@2|Bacteria,2GXBT@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1963)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
gnl|extdb|FAM1414-i1-1.1_000299	754252.PFREUD_06710	8.94e-77	228.0	COG1983@1|root,COG1983@2|Bacteria,2IRZU@201174|Actinobacteria	201174|Actinobacteria	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
gnl|extdb|FAM1414-i1-1.1_000300	754252.PFREUD_06720	1.03e-279	767.0	COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DNII@85009|Propionibacteriales	201174|Actinobacteria	T	PspC domain	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
gnl|extdb|FAM1414-i1-1.1_000301	754252.PFREUD_06730	1.68e-158	445.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4DQ1R@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
gnl|extdb|FAM1414-i1-1.1_000302	754252.PFREUD_06740	6.09e-53	166.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	MA20_40075	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
gnl|extdb|FAM1414-i1-1.1_000303	754252.PFREUD_06750	8.07e-235	647.0	COG4607@1|root,COG4607@2|Bacteria,2GK6Q@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type enterochelin transport system periplasmic component	feuS	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
gnl|extdb|FAM1414-i1-1.1_000305	754252.PFREUD_06770	2.15e-227	630.0	COG4605@1|root,COG4605@2|Bacteria,2GN2I@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	feuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
gnl|extdb|FAM1414-i1-1.1_000306	754252.PFREUD_06780	1.99e-174	486.0	COG4604@1|root,COG4604@2|Bacteria,2I2KS@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	feuA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000307	754252.PFREUD_06790	2.11e-311	847.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,4DP3Y@85009|Propionibacteriales	201174|Actinobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
gnl|extdb|FAM1414-i1-1.1_000308	754252.PFREUD_06800	0.0	1618.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4DP2M@85009|Propionibacteriales	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
gnl|extdb|FAM1414-i1-1.1_000309	754252.PFREUD_06810	0.0	896.0	COG3266@1|root,COG3266@2|Bacteria,2I39E@201174|Actinobacteria,4DX1A@85009|Propionibacteriales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000310	754252.PFREUD_06820	5.95e-140	395.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4DPAW@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
gnl|extdb|FAM1414-i1-1.1_000311	754252.PFREUD_06830	0.0	1003.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4DP1R@85009|Propionibacteriales	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
gnl|extdb|FAM1414-i1-1.1_000312	754252.PFREUD_06840	1.25e-205	568.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4DNC5@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
gnl|extdb|FAM1414-i1-1.1_000313	754252.PFREUD_06850	6.68e-68	206.0	2DRQP@1|root,33CNM@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3017
gnl|extdb|FAM1414-i1-1.1_000314	754252.PFREUD_06860	2.14e-234	645.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4DN1I@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
gnl|extdb|FAM1414-i1-1.1_000315	754252.PFREUD_06870	1.99e-303	826.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
gnl|extdb|FAM1414-i1-1.1_000318	754252.PFREUD_06900	0.0	959.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4DPDV@85009|Propionibacteriales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
gnl|extdb|FAM1414-i1-1.1_000320	754252.PFREUD_06920	5.04e-237	654.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria	201174|Actinobacteria	S	basic membrane	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
gnl|extdb|FAM1414-i1-1.1_000321	754252.PFREUD_06930	2.85e-242	666.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4DR5Z@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
gnl|extdb|FAM1414-i1-1.1_000322	754252.PFREUD_06940	3.59e-123	350.0	COG1514@1|root,COG1514@2|Bacteria,2I096@201174|Actinobacteria,4DWBJ@85009|Propionibacteriales	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
gnl|extdb|FAM1414-i1-1.1_000323	754252.PFREUD_06950	9.27e-220	606.0	COG1024@1|root,COG1024@2|Bacteria,2GMET@201174|Actinobacteria,4DR5H@85009|Propionibacteriales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA9	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
gnl|extdb|FAM1414-i1-1.1_000324	754252.PFREUD_06960	0.0	1156.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4DNQ0@85009|Propionibacteriales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
gnl|extdb|FAM1414-i1-1.1_000325	754252.PFREUD_06970	3.84e-231	635.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4DPHU@85009|Propionibacteriales	201174|Actinobacteria	K	Sir2 family	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
gnl|extdb|FAM1414-i1-1.1_000326	754252.PFREUD_06980	4e-148	417.0	COG2323@1|root,COG2323@2|Bacteria,2IEEX@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
gnl|extdb|FAM1414-i1-1.1_000327	754252.PFREUD_06990	1.35e-97	284.0	2A77J@1|root,30W3R@2|Bacteria,2GVFK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3290
gnl|extdb|FAM1414-i1-1.1_000328	754252.PFREUD_07000	5.81e-80	237.0	COG0789@1|root,COG0789@2|Bacteria,2IFX0@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
gnl|extdb|FAM1414-i1-1.1_000329	754252.PFREUD_07010	3.6e-92	269.0	COG0599@1|root,COG0599@2|Bacteria,2HFD1@201174|Actinobacteria,4DVHT@85009|Propionibacteriales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
gnl|extdb|FAM1414-i1-1.1_000330	1423732.BALS01000013_gene1548	2.7e-09	57.8	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,3F9HM@33958|Lactobacillaceae	91061|Bacilli	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
gnl|extdb|FAM1414-i1-1.1_000332	754252.PFREUD_07030	3.74e-149	419.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
gnl|extdb|FAM1414-i1-1.1_000333	754252.PFREUD_07050	2.66e-249	684.0	COG1063@1|root,COG1063@2|Bacteria,2GNFX@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
gnl|extdb|FAM1414-i1-1.1_000334	754252.PFREUD_07060	0.0	1170.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
gnl|extdb|FAM1414-i1-1.1_000335	754252.PFREUD_07070	0.0	2447.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,2I995@201174|Actinobacteria,4DVUV@85009|Propionibacteriales	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
gnl|extdb|FAM1414-i1-1.1_000336	754252.PFREUD_07080	1.29e-234	646.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
gnl|extdb|FAM1414-i1-1.1_000337	754252.PFREUD_07090	7.59e-127	360.0	COG1514@1|root,COG1514@2|Bacteria,2IKSA@201174|Actinobacteria,4DR0W@85009|Propionibacteriales	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
gnl|extdb|FAM1414-i1-1.1_000338	754252.PFREUD_07100	0.0	1162.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DMZN@85009|Propionibacteriales	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	bccA	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
gnl|extdb|FAM1414-i1-1.1_000339	754252.PFREUD_07110	1.36e-206	570.0	COG0266@1|root,COG0266@2|Bacteria,2GKUI@201174|Actinobacteria,4DN81@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the FPG family	nei1	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K05522,ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
gnl|extdb|FAM1414-i1-1.1_000340	765123.HMPREF9621_02000	8.69e-20	89.4	COG2235@1|root,COG2235@2|Bacteria	2|Bacteria	E	arginine	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
gnl|extdb|FAM1414-i1-1.1_000341	754252.PFREUD_07140	1.62e-99	292.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria	201174|Actinobacteria	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_000342	754252.PFREUD_07150	7.16e-174	484.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4DQJD@85009|Propionibacteriales	201174|Actinobacteria	D	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
gnl|extdb|FAM1414-i1-1.1_000344	754252.PFREUD_07170	0.0	1043.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DNBQ@85009|Propionibacteriales	201174|Actinobacteria	I	Carboxyl transferase domain	pccB	GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
gnl|extdb|FAM1414-i1-1.1_000345	754252.PFREUD_07180	0.0	876.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria	2|Bacteria	H	response to peptide	yjjP	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
gnl|extdb|FAM1414-i1-1.1_000346	754252.PFREUD_07200	1.63e-242	676.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4DPHI@85009|Propionibacteriales	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
gnl|extdb|FAM1414-i1-1.1_000347	754252.PFREUD_07210	1.04e-218	604.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4DPD1@85009|Propionibacteriales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
gnl|extdb|FAM1414-i1-1.1_000348	754252.PFREUD_07220	4.03e-125	355.0	2DWTW@1|root,341UU@2|Bacteria,2GPSK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000349	754252.PFREUD_07230	7.01e-133	377.0	COG1510@1|root,COG1510@2|Bacteria,2GNYV@201174|Actinobacteria,4DRAY@85009|Propionibacteriales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
gnl|extdb|FAM1414-i1-1.1_000350	754252.PFREUD_07240	2.94e-130	370.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K21961	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_000351	754252.PFREUD_07250	5.72e-195	540.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4DQT5@85009|Propionibacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
gnl|extdb|FAM1414-i1-1.1_000352	754252.PFREUD_07260	1.21e-110	318.0	COG3428@1|root,COG3428@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2,bPH_4
gnl|extdb|FAM1414-i1-1.1_000353	754252.PFREUD_07280	1.08e-133	379.0	COG1309@1|root,COG1309@2|Bacteria,2GX8K@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_000354	754252.PFREUD_07290	1.29e-174	486.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4DR4C@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
gnl|extdb|FAM1414-i1-1.1_000355	754252.PFREUD_07300	1.59e-287	785.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4DPHF@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
gnl|extdb|FAM1414-i1-1.1_000357	754252.PFREUD_07320	3.98e-311	849.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4DPY2@85009|Propionibacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
gnl|extdb|FAM1414-i1-1.1_000358	754252.PFREUD_07330	3.42e-258	707.0	COG0836@1|root,COG0836@2|Bacteria,2GIRM@201174|Actinobacteria,4DPTJ@85009|Propionibacteriales	201174|Actinobacteria	M	Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
gnl|extdb|FAM1414-i1-1.1_000359	754252.PFREUD_07340	1.08e-218	608.0	2956M@1|root,2ZSJ3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000360	754252.PFREUD_07350	1.02e-59	183.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4DRN7@85009|Propionibacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
gnl|extdb|FAM1414-i1-1.1_000361	754252.PFREUD_07360	0.0	2118.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4DN93@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
gnl|extdb|FAM1414-i1-1.1_000362	1035308.AQYY01000001_gene3570	2.33e-07	61.6	2EC47@1|root,33632@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000363	754252.PFREUD_07380	7.06e-102	295.0	COG3824@1|root,COG3824@2|Bacteria,2GR5W@201174|Actinobacteria,4DS4T@85009|Propionibacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
gnl|extdb|FAM1414-i1-1.1_000364	1122994.AUFR01000021_gene225	2.49e-51	165.0	2C7XW@1|root,32RR4@2|Bacteria,2IQ5R@201174|Actinobacteria,4DRSS@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3499
gnl|extdb|FAM1414-i1-1.1_000365	754252.PFREUD_07400	5.49e-197	545.0	COG0561@1|root,COG0561@2|Bacteria,2HZD0@201174|Actinobacteria	201174|Actinobacteria	T	HAD hydrolase, family IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,PMM
gnl|extdb|FAM1414-i1-1.1_000366	754252.PFREUD_07410	7.28e-42	137.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	ycaR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.7.1.130	ko:K00912,ko:K09791	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Trm112p
gnl|extdb|FAM1414-i1-1.1_000367	754252.PFREUD_07420	5.58e-226	624.0	COG1737@1|root,COG1737@2|Bacteria,2GMG0@201174|Actinobacteria,4DMZS@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
gnl|extdb|FAM1414-i1-1.1_000368	754252.PFREUD_07430	1.08e-221	615.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4DPUX@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
gnl|extdb|FAM1414-i1-1.1_000369	754252.PFREUD_07440	9.4e-61	186.0	2CAFG@1|root,32RRB@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
gnl|extdb|FAM1414-i1-1.1_000370	754252.PFREUD_07450	0.0	916.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria,4DQFD@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_000371	754252.PFREUD_07460	1.05e-197	554.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,RDD
gnl|extdb|FAM1414-i1-1.1_000372	754252.PFREUD_07470	0.0	1499.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4DPPR@85009|Propionibacteriales	201174|Actinobacteria	G	4-alpha-glucanotransferase	malQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
gnl|extdb|FAM1414-i1-1.1_000373	754252.PFREUD_07480	5.43e-230	634.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4DNKN@85009|Propionibacteriales	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
gnl|extdb|FAM1414-i1-1.1_000377	754252.PFREUD_07520	0.0	865.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4DPGF@85009|Propionibacteriales	201174|Actinobacteria	HQ	Isochorismate synthase	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
gnl|extdb|FAM1414-i1-1.1_000378	754252.PFREUD_07530	3.24e-291	795.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4DP67@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme	menE	-	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
gnl|extdb|FAM1414-i1-1.1_000379	754252.PFREUD_07540	1.79e-245	673.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4DNED@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
gnl|extdb|FAM1414-i1-1.1_000380	754252.PFREUD_07550	0.0	874.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4DN3A@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
gnl|extdb|FAM1414-i1-1.1_000381	754252.PFREUD_07560	9.17e-67	202.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4DRQZ@85009|Propionibacteriales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
gnl|extdb|FAM1414-i1-1.1_000382	754252.PFREUD_07570	7.3e-147	413.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4DQGY@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
gnl|extdb|FAM1414-i1-1.1_000383	754252.PFREUD_07580	3.85e-193	536.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4DP8J@85009|Propionibacteriales	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
gnl|extdb|FAM1414-i1-1.1_000384	754252.PFREUD_07590	1.49e-176	492.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4DN7G@85009|Propionibacteriales	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
gnl|extdb|FAM1414-i1-1.1_000385	754252.PFREUD_07600	1.15e-192	534.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4DQ0I@85009|Propionibacteriales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
gnl|extdb|FAM1414-i1-1.1_000386	754252.PFREUD_07610	7.58e-208	573.0	COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4DPMT@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
gnl|extdb|FAM1414-i1-1.1_000388	754252.PFREUD_07630	0.0	922.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DN0X@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
gnl|extdb|FAM1414-i1-1.1_000389	754252.PFREUD_07640	6.13e-234	644.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DP5N@85009|Propionibacteriales	201174|Actinobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
gnl|extdb|FAM1414-i1-1.1_000390	754252.PFREUD_07650	0.0	1431.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4DWYX@85009|Propionibacteriales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
gnl|extdb|FAM1414-i1-1.1_000391	754252.PFREUD_07660	0.0	1235.0	COG1884@1|root,COG1884@2|Bacteria,2GNBQ@201174|Actinobacteria,4DNT9@85009|Propionibacteriales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	mutA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
gnl|extdb|FAM1414-i1-1.1_000392	754252.PFREUD_07680	1.54e-171	480.0	COG2243@1|root,COG2243@2|Bacteria,2GUI0@201174|Actinobacteria	201174|Actinobacteria	H	Precorrin-2 C(20)-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
gnl|extdb|FAM1414-i1-1.1_000393	754252.PFREUD_07690	1.09e-227	627.0	COG2875@1|root,COG2875@2|Bacteria,2GJ97@201174|Actinobacteria,4DPG8@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the precorrin methyltransferase family	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
gnl|extdb|FAM1414-i1-1.1_000394	754252.PFREUD_07700	0.0	1660.0	COG1010@1|root,COG2073@1|root,COG2241@1|root,COG1010@2|Bacteria,COG2073@2|Bacteria,COG2241@2|Bacteria,2GMIR@201174|Actinobacteria,4DPRG@85009|Propionibacteriales	201174|Actinobacteria	H	precorrin-3B C17-methyltransferase	cobJ	-	2.1.1.131,3.7.1.12	ko:K13541	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R07772	RC00003,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,TP_methylase
gnl|extdb|FAM1414-i1-1.1_000395	754252.PFREUD_07710	1.85e-296	809.0	COG1648@1|root,COG2138@1|root,COG1648@2|Bacteria,COG2138@2|Bacteria,2I4ST@201174|Actinobacteria,4DWGC@85009|Propionibacteriales	201174|Actinobacteria	H	Putative NAD(P)-binding	-	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7
gnl|extdb|FAM1414-i1-1.1_000396	754252.PFREUD_07720	1.45e-295	808.0	COG1903@1|root,COG1903@2|Bacteria,2GM41@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
gnl|extdb|FAM1414-i1-1.1_000397	754252.PFREUD_07730	1.18e-146	414.0	COG2082@1|root,COG2082@2|Bacteria,2GK0B@201174|Actinobacteria,4DPQK@85009|Propionibacteriales	201174|Actinobacteria	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
gnl|extdb|FAM1414-i1-1.1_000398	754252.PFREUD_07750	1.87e-144	406.0	COG2242@1|root,COG2242@2|Bacteria,2GM8G@201174|Actinobacteria,4DNG6@85009|Propionibacteriales	201174|Actinobacteria	H	Precorrin-6y C5,15-methyltransferase	cobL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2072c	PCMT,TP_methylase
gnl|extdb|FAM1414-i1-1.1_000399	754252.PFREUD_07760	1.98e-182	507.0	COG2099@1|root,COG2099@2|Bacteria,2GMYZ@201174|Actinobacteria,4DPKR@85009|Propionibacteriales	201174|Actinobacteria	H	reductase	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
gnl|extdb|FAM1414-i1-1.1_000400	754252.PFREUD_07770	4.16e-167	466.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,4DNAZ@85009|Propionibacteriales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
gnl|extdb|FAM1414-i1-1.1_000402	754252.PFREUD_07790	7.36e-114	326.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4DQGR@85009|Propionibacteriales	201174|Actinobacteria	O	Redoxin	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
gnl|extdb|FAM1414-i1-1.1_000403	1120954.ATXE01000003_gene587	3.67e-11	62.0	296K5@1|root,2ZTVJ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
gnl|extdb|FAM1414-i1-1.1_000404	754252.PFREUD_07810	1.21e-99	289.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4DR8F@85009|Propionibacteriales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
gnl|extdb|FAM1414-i1-1.1_000406	754252.PFREUD_07830	3.56e-186	517.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4DUT1@85009|Propionibacteriales	201174|Actinobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
gnl|extdb|FAM1414-i1-1.1_000407	754252.PFREUD_07840	0.0	880.0	COG0769@1|root,COG0769@2|Bacteria,2I2TV@201174|Actinobacteria,4DU2N@85009|Propionibacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
gnl|extdb|FAM1414-i1-1.1_000408	754252.PFREUD_07850	3.19e-187	521.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4DVE3@85009|Propionibacteriales	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
gnl|extdb|FAM1414-i1-1.1_000409	754252.PFREUD_07860	0.0	1533.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DN67@85009|Propionibacteriales	201174|Actinobacteria	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000410	754252.PFREUD_07870	1.16e-113	326.0	COG0317@1|root,COG0317@2|Bacteria,2IHTX@201174|Actinobacteria	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
gnl|extdb|FAM1414-i1-1.1_000413	327277.JHAL01000002_gene372	5.83e-55	174.0	2EBVN@1|root,335V2@2|Bacteria,2IR7Q@201174|Actinobacteria,4D2BT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000414	888050.HMPREF9004_0544	0.0	943.0	2DBH4@1|root,2Z97J@2|Bacteria,2I8MI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000415	888050.HMPREF9004_0545	9.69e-46	147.0	2AM2S@1|root,31BWT@2|Bacteria,2HMYJ@201174|Actinobacteria,4D7R1@85005|Actinomycetales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2188
gnl|extdb|FAM1414-i1-1.1_000416	888050.HMPREF9004_0546	4.61e-240	663.0	COG2856@1|root,COG2856@2|Bacteria,2GRH0@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,Peptidase_M78
gnl|extdb|FAM1414-i1-1.1_000418	1178540.BA70_01040	1.5e-73	251.0	COG0827@1|root,COG0827@2|Bacteria,1U6WB@1239|Firmicutes,4HEXF@91061|Bacilli,1ZJKW@1386|Bacillus	91061|Bacilli	L	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
gnl|extdb|FAM1414-i1-1.1_000419	67281.JNZZ01000026_gene4961	4.8e-219	613.0	COG3886@1|root,COG3886@2|Bacteria,2H1ND@201174|Actinobacteria	201174|Actinobacteria	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
gnl|extdb|FAM1414-i1-1.1_000420	1115632.JAFW01000001_gene4167	2.3e-120	363.0	28IDI@1|root,2Z8FT@2|Bacteria,2I4VR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000423	928724.SacglDRAFT_02671	5.77e-56	182.0	COG1309@1|root,COG1309@2|Bacteria,2IP3P@201174|Actinobacteria,4E5ZE@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_000425	136273.GY22_00430	9.22e-43	146.0	2B2NA@1|root,31V7X@2|Bacteria,2I84M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000426	77635.BISU_1956	1.81e-151	433.0	COG4977@1|root,COG4977@2|Bacteria,2I4ZH@201174|Actinobacteria	201174|Actinobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
gnl|extdb|FAM1414-i1-1.1_000427	77635.BISU_1955	4.71e-198	556.0	COG2856@1|root,COG2856@2|Bacteria,2GMAA@201174|Actinobacteria,4D0DQ@85004|Bifidobacteriales	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
gnl|extdb|FAM1414-i1-1.1_000428	218140.BPSY_0774	1.35e-151	433.0	COG5519@1|root,COG5519@2|Bacteria,2HZHJ@201174|Actinobacteria,4D0GR@85004|Bifidobacteriales	201174|Actinobacteria	L	Primase C terminal 1 (PriCT-1)	-	-	-	-	-	-	-	-	-	-	-	-	PriCT_1,Prim-Pol
gnl|extdb|FAM1414-i1-1.1_000429	327277.JHAL01000002_gene360	4.71e-109	322.0	COG3415@1|root,COG3415@2|Bacteria,2I8K3@201174|Actinobacteria,4CZQM@85004|Bifidobacteriales	201174|Actinobacteria	L	Protein of unknown function (DUF2637)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2637,HTH_23,HTH_38
gnl|extdb|FAM1414-i1-1.1_000430	218140.BPSY_0776	8.29e-37	129.0	2CJWA@1|root,330VP@2|Bacteria,2GPWV@201174|Actinobacteria,4D1DC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000431	218140.BPSY_0777	2.15e-164	465.0	28KES@1|root,2ZA10@2|Bacteria,2GJPN@201174|Actinobacteria,4D01M@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000432	218140.BPSY_0778	7.99e-174	491.0	COG1475@1|root,COG1475@2|Bacteria,2HTYC@201174|Actinobacteria,4D0GC@85004|Bifidobacteriales	201174|Actinobacteria	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
gnl|extdb|FAM1414-i1-1.1_000433	327277.JHAL01000002_gene354	9.78e-107	313.0	2DBHA@1|root,2Z986@2|Bacteria,2IE6S@201174|Actinobacteria,4CYSR@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000435	327277.JHAL01000002_gene349	3.93e-44	145.0	2E1EX@1|root,32WTQ@2|Bacteria,2IRYZ@201174|Actinobacteria,4D18A@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000436	327277.JHAL01000002_gene348	5.95e-62	191.0	2E3QT@1|root,32YNN@2|Bacteria,2IKY3@201174|Actinobacteria,4D14W@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000437	327277.JHAL01000002_gene347	1.77e-196	561.0	COG3266@1|root,COG3266@2|Bacteria,2GN4E@201174|Actinobacteria,4D0EC@85004|Bifidobacteriales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
gnl|extdb|FAM1414-i1-1.1_000438	77635.BISU_1830	0.0	867.0	28IJ8@1|root,2Z8K6@2|Bacteria,2GIV3@201174|Actinobacteria,4CZPS@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EccE
gnl|extdb|FAM1414-i1-1.1_000439	327277.JHAL01000002_gene345	2.16e-120	351.0	28JTD@1|root,2Z9IP@2|Bacteria,2IB6M@201174|Actinobacteria,4D1WQ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000440	77635.BISU_1832	0.0	887.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4D0A1@85004|Bifidobacteriales	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000441	1125718.HMPREF1318_1743	1.22e-107	315.0	2C959@1|root,32RNM@2|Bacteria,2GTV3@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4145
gnl|extdb|FAM1414-i1-1.1_000442	218140.BPSY_0786	3.74e-60	189.0	29K3G@1|root,3070W@2|Bacteria,2IINK@201174|Actinobacteria,4D0RR@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000443	218140.BPSY_0787	0.0	1016.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria,4D08H@85004|Bifidobacteriales	201174|Actinobacteria	U	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	TraG-D_C
gnl|extdb|FAM1414-i1-1.1_000445	77635.BISU_1837	3.38e-109	317.0	28Q31@1|root,2ZCKT@2|Bacteria,2IFAQ@201174|Actinobacteria,4CZ7H@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000449	754252.PFREUD_07900	5.76e-286	783.0	COG0477@1|root,COG2814@2|Bacteria,2H0CW@201174|Actinobacteria,4DN0M@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_000451	754252.PFREUD_07920	0.0	954.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4DQ3Y@85009|Propionibacteriales	201174|Actinobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
gnl|extdb|FAM1414-i1-1.1_000452	754252.PFREUD_07930	0.0	1088.0	COG0699@1|root,COG0699@2|Bacteria,2GJX9@201174|Actinobacteria,4DPB6@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
gnl|extdb|FAM1414-i1-1.1_000453	754252.PFREUD_07940	0.0	1027.0	COG0699@1|root,COG0699@2|Bacteria,2GM68@201174|Actinobacteria,4DPRU@85009|Propionibacteriales	201174|Actinobacteria	S	50S ribosome-binding GTPase	PPA1638	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
gnl|extdb|FAM1414-i1-1.1_000454	754252.PFREUD_07950	2.42e-161	451.0	COG0412@1|root,COG0412@2|Bacteria,2IG1G@201174|Actinobacteria,4DVST@85009|Propionibacteriales	201174|Actinobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000455	754252.PFREUD_07960	1.25e-107	311.0	COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,4DS96@85009|Propionibacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb2	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
gnl|extdb|FAM1414-i1-1.1_000456	754252.PFREUD_07970	0.0	1121.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4DNB9@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
gnl|extdb|FAM1414-i1-1.1_000457	754252.PFREUD_07980	2.83e-236	650.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4DN06@85009|Propionibacteriales	201174|Actinobacteria	G	Dihydroxyacetone kinase	dhaK	-	2.7.1.121,2.7.1.209,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878,ko:K20901	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059,R11460	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1
gnl|extdb|FAM1414-i1-1.1_000458	754252.PFREUD_07990	1.1e-138	393.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4DQSR@85009|Propionibacteriales	201174|Actinobacteria	S	Dak2	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
gnl|extdb|FAM1414-i1-1.1_000459	754252.PFREUD_08000	0.0	901.0	COG1080@1|root,COG1925@1|root,COG3412@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG3412@2|Bacteria,2GIZZ@201174|Actinobacteria,4DNRM@85009|Propionibacteriales	201174|Actinobacteria	G	PTS system fructose IIA component	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
gnl|extdb|FAM1414-i1-1.1_000460	754252.PFREUD_08010	0.0	947.0	COG1085@1|root,COG1085@2|Bacteria,2IA73@201174|Actinobacteria	201174|Actinobacteria	C	uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4921
gnl|extdb|FAM1414-i1-1.1_000461	754252.PFREUD_08030	0.0	1354.0	COG0339@1|root,COG0339@2|Bacteria,2GM2Z@201174|Actinobacteria	201174|Actinobacteria	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
gnl|extdb|FAM1414-i1-1.1_000462	754252.PFREUD_08040	0.0	1895.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4DN5D@85009|Propionibacteriales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
gnl|extdb|FAM1414-i1-1.1_000463	754252.PFREUD_08050	3.57e-98	286.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,4DR7Q@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
gnl|extdb|FAM1414-i1-1.1_000464	754252.PFREUD_08060	0.0	1259.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DNTY@85009|Propionibacteriales	201174|Actinobacteria	I	AMP-binding enzyme	fadD11_1	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
gnl|extdb|FAM1414-i1-1.1_000465	754252.PFREUD_08070	6.52e-216	595.0	COG0824@1|root,COG0824@2|Bacteria,2IFAK@201174|Actinobacteria,4DRTF@85009|Propionibacteriales	201174|Actinobacteria	S	Acyl-ACP thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
gnl|extdb|FAM1414-i1-1.1_000466	754252.PFREUD_08080	1.39e-191	532.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
gnl|extdb|FAM1414-i1-1.1_000467	754252.PFREUD_08090	0.0	971.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4DQ33@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
gnl|extdb|FAM1414-i1-1.1_000468	754252.PFREUD_08100	0.0	1717.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4DNEA@85009|Propionibacteriales	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
gnl|extdb|FAM1414-i1-1.1_000018	754252.PFREUD_04370	8.59e-290	792.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4DTJP@85009|Propionibacteriales	201174|Actinobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
gnl|extdb|FAM1414-i1-1.1_000056	754252.PFREUD_04770	0.0	1009.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4DN2S@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
gnl|extdb|FAM1414-i1-1.1_000080	1385518.N798_00785	1.03e-09	57.8	2CC1Y@1|root,32G41@2|Bacteria,2GPTR@201174|Actinobacteria,4FHEV@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	-	-	-	-	-	-	-	-	-	Whib
gnl|extdb|FAM1414-i1-1.1_000121	1125718.HMPREF1318_2354	3.36e-14	72.4	2BWS4@1|root,32XQ0@2|Bacteria,2GR3P@201174|Actinobacteria,4D7SW@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000129	754252.PFREUD_04940	2.04e-204	567.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
gnl|extdb|FAM1414-i1-1.1_000139	754252.PFREUD_05060	6.75e-180	509.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4DNW0@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
gnl|extdb|FAM1414-i1-1.1_000147	754252.PFREUD_05140	0.0	880.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4DPE1@85009|Propionibacteriales	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
gnl|extdb|FAM1414-i1-1.1_000159	754252.PFREUD_05270	0.0	1197.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4DP65@85009|Propionibacteriales	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
gnl|extdb|FAM1414-i1-1.1_000173	754252.PFREUD_05410	2.29e-136	385.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria	201174|Actinobacteria	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
gnl|extdb|FAM1414-i1-1.1_000183	754252.PFREUD_05510	4.71e-98	287.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,4DSA3@85009|Propionibacteriales	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
gnl|extdb|FAM1414-i1-1.1_000215	754252.PFREUD_05830	2.28e-142	402.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4DNUQ@85009|Propionibacteriales	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
gnl|extdb|FAM1414-i1-1.1_000231	754252.PFREUD_05990	7.51e-195	540.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4DNQ9@85009|Propionibacteriales	201174|Actinobacteria	J	Methionine aminopeptidase	mapA	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
gnl|extdb|FAM1414-i1-1.1_000244	754252.PFREUD_06120	5.21e-159	451.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000246	754252.PFREUD_06140	2.44e-176	493.0	COG1122@1|root,COG1122@2|Bacteria,2GMK1@201174|Actinobacteria,4DQPM@85009|Propionibacteriales	201174|Actinobacteria	P	ECF transporter, substrate-specific component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF_trnsprt
gnl|extdb|FAM1414-i1-1.1_000253	754252.PFREUD_06220	8.81e-79	235.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4DRE0@85009|Propionibacteriales	201174|Actinobacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
gnl|extdb|FAM1414-i1-1.1_000263	754252.PFREUD_06320	0.0	983.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DNT3@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	rhlE_2	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
gnl|extdb|FAM1414-i1-1.1_000264	754252.PFREUD_06330	3.05e-171	482.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4DPK9@85009|Propionibacteriales	201174|Actinobacteria	K	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
gnl|extdb|FAM1414-i1-1.1_000271	754252.PFREUD_06400	5.12e-247	684.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4DP19@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
gnl|extdb|FAM1414-i1-1.1_000281	754252.PFREUD_06500	8.52e-65	197.0	COG1605@1|root,COG1605@2|Bacteria,2IQ46@201174|Actinobacteria	201174|Actinobacteria	E	Chorismate mutase	tyrA	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
gnl|extdb|FAM1414-i1-1.1_000286	754252.PFREUD_06550	1.51e-110	319.0	COG1045@1|root,COG1045@2|Bacteria,2IHW5@201174|Actinobacteria,4DSPI@85009|Propionibacteriales	201174|Actinobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
gnl|extdb|FAM1414-i1-1.1_000298	754252.PFREUD_06700	2.38e-222	613.0	COG0604@1|root,COG0604@2|Bacteria,2HWXG@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
gnl|extdb|FAM1414-i1-1.1_000304	754252.PFREUD_06760	3.61e-198	552.0	COG4606@1|root,COG4606@2|Bacteria,2GNC7@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	feuB	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
gnl|extdb|FAM1414-i1-1.1_000316	1035308.AQYY01000001_gene1840	2.05e-30	110.0	2E45J@1|root,32Z1K@2|Bacteria	2|Bacteria	S	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
gnl|extdb|FAM1414-i1-1.1_000317	754252.PFREUD_06890	4.14e-154	433.0	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4DQH9@85009|Propionibacteriales	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
gnl|extdb|FAM1414-i1-1.1_000319	754252.PFREUD_06910	1.86e-295	807.0	COG3173@1|root,COG3173@2|Bacteria,2I4D0@201174|Actinobacteria,4DX20@85009|Propionibacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
gnl|extdb|FAM1414-i1-1.1_000343	754252.PFREUD_07160	2.98e-58	179.0	2DFKT@1|root,2ZS8K@2|Bacteria,2GT3J@201174|Actinobacteria	201174|Actinobacteria	S	Acyl-CoA carboxylase epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_epsilon
gnl|extdb|FAM1414-i1-1.1_000356	754252.PFREUD_07310	2.37e-103	300.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4DQ6R@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
gnl|extdb|FAM1414-i1-1.1_000374	754252.PFREUD_07490	0.0	985.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4DPUU@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
gnl|extdb|FAM1414-i1-1.1_000375	754252.PFREUD_07500	0.0	1651.0	COG0178@1|root,COG0178@2|Bacteria,2GNMW@201174|Actinobacteria	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA3	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000387	754252.PFREUD_07620	8.97e-147	413.0	COG0262@1|root,COG0262@2|Bacteria,2IM1S@201174|Actinobacteria	201174|Actinobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1,NUDIX
gnl|extdb|FAM1414-i1-1.1_000434	218140.BPSY_0780	3.3e-225	629.0	COG0739@1|root,COG0739@2|Bacteria,2GKXN@201174|Actinobacteria,4D079@85004|Bifidobacteriales	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
gnl|extdb|FAM1414-i1-1.1_000444	327277.JHAL01000002_gene341	1.27e-96	283.0	COG0629@1|root,COG0629@2|Bacteria,2IMCN@201174|Actinobacteria,4D1D0@85004|Bifidobacteriales	201174|Actinobacteria	L	single-stranded DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	SSB
gnl|extdb|FAM1414-i1-1.1_000448	754252.PFREUD_07890	7.18e-160	447.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4DPKU@85009|Propionibacteriales	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
gnl|extdb|FAM1414-i1-1.1_000065	653386.HMPREF0975_00230	5.35e-53	179.0	COG1131@1|root,COG1131@2|Bacteria,2GJ84@201174|Actinobacteria,4D4D6@85005|Actinomycetales	201174|Actinobacteria	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_000926	754252.PFREUD_10700	0.0	1588.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4DPSB@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
gnl|extdb|FAM1414-i1-1.1_000927	754252.PFREUD_10710	3.05e-260	712.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4DPXG@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
gnl|extdb|FAM1414-i1-1.1_000928	754252.PFREUD_10720	6.2e-218	603.0	COG0620@1|root,COG0620@2|Bacteria,2GMPS@201174|Actinobacteria,4DN0J@85009|Propionibacteriales	201174|Actinobacteria	E	Methionine synthase, vitamin-B12 independent	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
gnl|extdb|FAM1414-i1-1.1_000930	754252.PFREUD_10740	5.09e-148	416.0	COG2061@1|root,COG2061@2|Bacteria,2I3KF@201174|Actinobacteria,4DR5N@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	-	-	-	-	-	-	-	-	-	-	ACT
gnl|extdb|FAM1414-i1-1.1_000931	754252.PFREUD_10750	1.46e-61	189.0	COG0721@1|root,COG0721@2|Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
gnl|extdb|FAM1414-i1-1.1_000932	754252.PFREUD_10760	0.0	975.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4DN5B@85009|Propionibacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
gnl|extdb|FAM1414-i1-1.1_000934	754252.PFREUD_10780	0.0	1356.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156,Rhomboid
gnl|extdb|FAM1414-i1-1.1_000935	1122994.AUFR01000001_gene1486	3.2e-146	430.0	COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria	201174|Actinobacteria	S	Esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
gnl|extdb|FAM1414-i1-1.1_000937	754252.PFREUD_10820	1.9e-94	275.0	COG2893@1|root,COG2893@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	manX1	-	2.7.1.191	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man,PTSIIB_sorb
gnl|extdb|FAM1414-i1-1.1_000938	754252.PFREUD_10830	5.67e-149	419.0	COG0517@1|root,COG0517@2|Bacteria,2GSAR@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
gnl|extdb|FAM1414-i1-1.1_000939	754252.PFREUD_10840	2.19e-155	437.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DPMH@85009|Propionibacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
gnl|extdb|FAM1414-i1-1.1_000940	754252.PFREUD_10850	2.69e-184	513.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DPPJ@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
gnl|extdb|FAM1414-i1-1.1_000941	754252.PFREUD_10860	4.42e-211	587.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4DNIE@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	braE	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
gnl|extdb|FAM1414-i1-1.1_000942	754252.PFREUD_10870	6.29e-194	540.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
gnl|extdb|FAM1414-i1-1.1_000943	754252.PFREUD_10880	8.62e-273	747.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4DQP9@85009|Propionibacteriales	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
gnl|extdb|FAM1414-i1-1.1_000944	754252.PFREUD_10890	0.0	910.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4DNBU@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpd	GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
gnl|extdb|FAM1414-i1-1.1_000945	754252.PFREUD_10900	0.0	995.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4DP2I@85009|Propionibacteriales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase,HTH_3
gnl|extdb|FAM1414-i1-1.1_000946	754252.PFREUD_10910	1.02e-201	559.0	COG2240@1|root,COG2240@2|Bacteria,2HS59@201174|Actinobacteria,4DNVS@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the pyridoxine kinase family	pdxY	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
gnl|extdb|FAM1414-i1-1.1_000947	1122994.AUFR01000001_gene1494	1.32e-47	160.0	2B5VP@1|root,31YRJ@2|Bacteria,2I057@201174|Actinobacteria,4DVSR@85009|Propionibacteriales	201174|Actinobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
gnl|extdb|FAM1414-i1-1.1_000949	754252.PFREUD_10940	4.95e-79	234.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4DQUX@85009|Propionibacteriales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
gnl|extdb|FAM1414-i1-1.1_000950	754252.PFREUD_10950	1.24e-191	532.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4DNYS@85009|Propionibacteriales	201174|Actinobacteria	S	Glycosyltransferase like family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
gnl|extdb|FAM1414-i1-1.1_000951	754252.PFREUD_10970	0.0	1056.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,4DP6S@85009|Propionibacteriales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
gnl|extdb|FAM1414-i1-1.1_000952	754252.PFREUD_10980	1.83e-101	294.0	COG1522@1|root,COG1522@2|Bacteria,2GK3G@201174|Actinobacteria,4DQJS@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix ASNC type	lrp_3	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
gnl|extdb|FAM1414-i1-1.1_000953	754252.PFREUD_10990	6.63e-163	456.0	COG0500@1|root,COG2226@2|Bacteria,2IDZY@201174|Actinobacteria,4DUY7@85009|Propionibacteriales	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW,Methyltransf_11
gnl|extdb|FAM1414-i1-1.1_000954	754252.PFREUD_11000	5.45e-302	822.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,4DNSW@85009|Propionibacteriales	201174|Actinobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
gnl|extdb|FAM1414-i1-1.1_000956	754252.PFREUD_11020	5.87e-231	637.0	COG0715@1|root,COG0715@2|Bacteria,2HFVC@201174|Actinobacteria,4DSW7@85009|Propionibacteriales	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
gnl|extdb|FAM1414-i1-1.1_000957	754252.PFREUD_11030	2.29e-197	548.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4DWQU@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_000958	754252.PFREUD_11040	0.0	989.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_000959	754252.PFREUD_11050	1.34e-112	322.0	COG1854@1|root,COG1854@2|Bacteria,2GJVF@201174|Actinobacteria	201174|Actinobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
gnl|extdb|FAM1414-i1-1.1_000961	754252.PFREUD_11180	1.69e-65	199.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	marR5	-	-	-	-	-	-	-	-	-	-	-	HTH_34
gnl|extdb|FAM1414-i1-1.1_000962	754252.PFREUD_11190	9.8e-113	324.0	2B48T@1|root,31X00@2|Bacteria,2GY61@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000963	754252.PFREUD_11200	1.37e-191	533.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria	201174|Actinobacteria	K	permease, DMT superfamily	rhtA_1	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
gnl|extdb|FAM1414-i1-1.1_000964	754252.PFREUD_11210	4.42e-221	610.0	COG0604@1|root,COG0604@2|Bacteria,2GMA2@201174|Actinobacteria,4DVUX@85009|Propionibacteriales	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_zinc_N
gnl|extdb|FAM1414-i1-1.1_000965	754252.PFREUD_11220	5.14e-131	372.0	COG1309@1|root,COG1309@2|Bacteria,2IR1F@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_000966	446468.Ndas_1066	9.66e-218	617.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4EHJM@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000967	754252.PFREUD_11250	2.96e-121	345.0	COG4283@1|root,COG4283@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
gnl|extdb|FAM1414-i1-1.1_000968	754252.PFREUD_11260	0.0	870.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4DNFK@85009|Propionibacteriales	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
gnl|extdb|FAM1414-i1-1.1_000969	754252.PFREUD_11270	3.02e-152	428.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
gnl|extdb|FAM1414-i1-1.1_000970	754252.PFREUD_11280	5.89e-257	705.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4DNB5@85009|Propionibacteriales	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
gnl|extdb|FAM1414-i1-1.1_000971	754252.PFREUD_11290	1.75e-169	473.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4DMZ3@85009|Propionibacteriales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
gnl|extdb|FAM1414-i1-1.1_000972	754252.PFREUD_11300	1.01e-199	553.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4DPD6@85009|Propionibacteriales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
gnl|extdb|FAM1414-i1-1.1_000973	754252.PFREUD_11310	1.77e-263	721.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4DNGH@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
gnl|extdb|FAM1414-i1-1.1_000974	754252.PFREUD_11320	3.02e-170	475.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4DQE5@85009|Propionibacteriales	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
gnl|extdb|FAM1414-i1-1.1_000975	754252.PFREUD_11330	1.66e-272	749.0	COG0616@1|root,COG0616@2|Bacteria	2|Bacteria	OU	serine-type peptidase activity	sppA	-	-	ko:K04773,ko:K21511	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49,SDH_sah
gnl|extdb|FAM1414-i1-1.1_000976	754252.PFREUD_11340	0.0	2293.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
gnl|extdb|FAM1414-i1-1.1_000977	754252.PFREUD_11350	4.54e-203	561.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4DWGD@85009|Propionibacteriales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
gnl|extdb|FAM1414-i1-1.1_000978	754252.PFREUD_11360	0.0	898.0	COG3579@1|root,COG3579@2|Bacteria,2GNYU@201174|Actinobacteria,4DQ4H@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase C1-like family	pepC2	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
gnl|extdb|FAM1414-i1-1.1_000979	754252.PFREUD_11370	1.69e-153	431.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4DNZI@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
gnl|extdb|FAM1414-i1-1.1_000980	754252.PFREUD_11380	0.0	889.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4DP4E@85009|Propionibacteriales	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
gnl|extdb|FAM1414-i1-1.1_000981	754252.PFREUD_11390	4.84e-229	630.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4DN9I@85009|Propionibacteriales	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
gnl|extdb|FAM1414-i1-1.1_000982	754252.PFREUD_11400	0.0	1342.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4DNMW@85009|Propionibacteriales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000983	754252.PFREUD_11410	8.54e-289	788.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4DN34@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
gnl|extdb|FAM1414-i1-1.1_000984	754252.PFREUD_11420	6.17e-77	229.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4DRNP@85009|Propionibacteriales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
gnl|extdb|FAM1414-i1-1.1_000985	754252.PFREUD_11430	7.24e-147	413.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4DQBB@85009|Propionibacteriales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
gnl|extdb|FAM1414-i1-1.1_000986	754252.PFREUD_11440	9.69e-66	200.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4DRRY@85009|Propionibacteriales	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000987	754252.PFREUD_11450	2.4e-190	528.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4DNH0@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
gnl|extdb|FAM1414-i1-1.1_000988	754252.PFREUD_11460	2.97e-267	731.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4DP48@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
gnl|extdb|FAM1414-i1-1.1_000989	754252.PFREUD_11470	0.0	2196.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4DNSQ@85009|Propionibacteriales	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
gnl|extdb|FAM1414-i1-1.1_000990	754252.PFREUD_11480	1.43e-295	805.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4DNY4@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
gnl|extdb|FAM1414-i1-1.1_000991	754252.PFREUD_11500	1.29e-141	400.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
gnl|extdb|FAM1414-i1-1.1_000992	754252.PFREUD_11510	2.31e-133	378.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
gnl|extdb|FAM1414-i1-1.1_000993	754252.PFREUD_11520	0.0	1071.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4DN6F@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
gnl|extdb|FAM1414-i1-1.1_000994	754252.PFREUD_11530	8.81e-284	776.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4DPU4@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
gnl|extdb|FAM1414-i1-1.1_000995	754252.PFREUD_11540	2.9e-294	803.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4DN3K@85009|Propionibacteriales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
gnl|extdb|FAM1414-i1-1.1_000996	754252.PFREUD_11550	3.13e-122	349.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4DR7E@85009|Propionibacteriales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
gnl|extdb|FAM1414-i1-1.1_000997	754252.PFREUD_11560	0.0	1769.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4DP1M@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
gnl|extdb|FAM1414-i1-1.1_000998	754252.PFREUD_11570	5.26e-234	644.0	COG0039@1|root,COG0039@2|Bacteria,2H3WC@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the LDH MDH superfamily	ldh1	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
gnl|extdb|FAM1414-i1-1.1_000999	754252.PFREUD_11580	0.0	898.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4DP5Q@85009|Propionibacteriales	201174|Actinobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
gnl|extdb|FAM1414-i1-1.1_001000	754252.PFREUD_11590	0.0	1238.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4DPC4@85009|Propionibacteriales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
gnl|extdb|FAM1414-i1-1.1_001001	754252.PFREUD_11600	9.5e-264	721.0	28IW2@1|root,2Z8UC@2|Bacteria,2IA78@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001003	754252.PFREUD_11620	0.0	875.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4DP1N@85009|Propionibacteriales	201174|Actinobacteria	J	Histidine--tRNA ligase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
gnl|extdb|FAM1414-i1-1.1_001004	754252.PFREUD_11630	1.13e-166	466.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4DNMS@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
gnl|extdb|FAM1414-i1-1.1_001005	754252.PFREUD_11640	1.09e-283	777.0	COG1196@1|root,COG1196@2|Bacteria,2GJBD@201174|Actinobacteria,4DNC8@85009|Propionibacteriales	201174|Actinobacteria	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
gnl|extdb|FAM1414-i1-1.1_001006	754252.PFREUD_11650	0.0	1559.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4DNJH@85009|Propionibacteriales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
gnl|extdb|FAM1414-i1-1.1_001007	754252.PFREUD_11660	7.41e-120	343.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
gnl|extdb|FAM1414-i1-1.1_001008	754252.PFREUD_11670	1.06e-278	764.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4DPBJ@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
gnl|extdb|FAM1414-i1-1.1_001009	754252.PFREUD_11680	0.0	1065.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4DP94@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
gnl|extdb|FAM1414-i1-1.1_001010	754252.PFREUD_11690	1.16e-108	313.0	COG1862@1|root,COG1862@2|Bacteria,2GXK0@201174|Actinobacteria,4DSPJ@85009|Propionibacteriales	201174|Actinobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
gnl|extdb|FAM1414-i1-1.1_001011	754252.PFREUD_11700	1.26e-244	672.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4DP63@85009|Propionibacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
gnl|extdb|FAM1414-i1-1.1_001012	754252.PFREUD_11710	8.11e-138	390.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4DQ7Y@85009|Propionibacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
gnl|extdb|FAM1414-i1-1.1_001013	754252.PFREUD_11720	2.06e-115	333.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4DQAA@85009|Propionibacteriales	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
gnl|extdb|FAM1414-i1-1.1_001014	754252.PFREUD_11730	2.45e-177	495.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4DN3U@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
gnl|extdb|FAM1414-i1-1.1_001015	754252.PFREUD_11740	3.71e-264	721.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K18566	ko00332,ko01130,map00332,map01130	-	R10745,R10746	RC00004,RC00096	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
gnl|extdb|FAM1414-i1-1.1_001016	754252.PFREUD_11750	2.49e-169	473.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4DMXV@85009|Propionibacteriales	201174|Actinobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
gnl|extdb|FAM1414-i1-1.1_001018	754252.PFREUD_11770	2.52e-136	386.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4DNSZ@85009|Propionibacteriales	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
gnl|extdb|FAM1414-i1-1.1_001019	754252.PFREUD_11780	2.57e-291	795.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4DPP5@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
gnl|extdb|FAM1414-i1-1.1_001020	754252.PFREUD_11790	1.21e-302	827.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4DMY2@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
gnl|extdb|FAM1414-i1-1.1_001021	754252.PFREUD_11800	1.86e-166	467.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria,4DPPY@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
gnl|extdb|FAM1414-i1-1.1_001022	754252.PFREUD_11810	8.44e-118	337.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,4DQRV@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
gnl|extdb|FAM1414-i1-1.1_001023	754252.PFREUD_11820	3.62e-165	462.0	2DVYJ@1|root,33XQ4@2|Bacteria,2HZGU@201174|Actinobacteria,4DSRP@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001024	754252.PFREUD_11830	0.0	2384.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DTRE@85009|Propionibacteriales	201174|Actinobacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
gnl|extdb|FAM1414-i1-1.1_001025	754252.PFREUD_11840	2.92e-134	383.0	COG3247@1|root,COG3247@2|Bacteria	2|Bacteria	U	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
gnl|extdb|FAM1414-i1-1.1_001026	754252.PFREUD_11850	0.0	997.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4DNI1@85009|Propionibacteriales	201174|Actinobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
gnl|extdb|FAM1414-i1-1.1_001027	754252.PFREUD_11860	0.0	2970.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,2GN09@201174|Actinobacteria,4DP8G@85009|Propionibacteriales	201174|Actinobacteria	E	GXGXG motif	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
gnl|extdb|FAM1414-i1-1.1_001028	754252.PFREUD_11870	2.17e-245	672.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4DP3T@85009|Propionibacteriales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
gnl|extdb|FAM1414-i1-1.1_001030	754252.PFREUD_11890	1.36e-307	837.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4DN45@85009|Propionibacteriales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
gnl|extdb|FAM1414-i1-1.1_001031	754252.PFREUD_11900	1.88e-191	533.0	COG3010@1|root,COG3010@2|Bacteria,2I4VZ@201174|Actinobacteria,4DX2K@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
gnl|extdb|FAM1414-i1-1.1_001033	754252.PFREUD_11920	7.97e-98	284.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4DR51@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
gnl|extdb|FAM1414-i1-1.1_001034	754252.PFREUD_11930	1.76e-168	470.0	COG0243@1|root,COG0243@2|Bacteria,2GJ62@201174|Actinobacteria,4DR20@85009|Propionibacteriales	201174|Actinobacteria	C	molybdopterin cofactor binding	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
gnl|extdb|FAM1414-i1-1.1_001035	754252.PFREUD_11940	0.0	1182.0	COG0008@1|root,COG0008@2|Bacteria,2H1TZ@201174|Actinobacteria	201174|Actinobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
gnl|extdb|FAM1414-i1-1.1_001036	754252.PFREUD_11950	4.05e-158	442.0	COG0406@1|root,COG0406@2|Bacteria,2I9GN@201174|Actinobacteria	201174|Actinobacteria	G	phosphoglycerate mutase	-	-	3.1.3.85,5.4.2.12	ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
gnl|extdb|FAM1414-i1-1.1_001038	754252.PFREUD_11970	1.6e-203	566.0	COG4120@1|root,COG4120@2|Bacteria,2I8VW@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
gnl|extdb|FAM1414-i1-1.1_001039	754252.PFREUD_11980	4.79e-178	497.0	COG1101@1|root,COG1101@2|Bacteria,2GNP6@201174|Actinobacteria,4DUW4@85009|Propionibacteriales	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001040	754252.PFREUD_11990	1.08e-247	680.0	COG1938@1|root,COG1938@2|Bacteria,2I2N7@201174|Actinobacteria,4DQ83@85009|Propionibacteriales	201174|Actinobacteria	S	PAC2 family	pac	-	-	-	-	-	-	-	-	-	-	-	PAC2
gnl|extdb|FAM1414-i1-1.1_001041	754252.PFREUD_12000	5.51e-199	550.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4DREC@85009|Propionibacteriales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	rifO	-	-	-	-	-	-	-	-	-	-	-	PIG-L
gnl|extdb|FAM1414-i1-1.1_001042	754252.PFREUD_12010	3.49e-139	398.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria	201174|Actinobacteria	NU	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
gnl|extdb|FAM1414-i1-1.1_001043	754252.PFREUD_12020	3.32e-147	414.0	COG0009@1|root,COG0009@2|Bacteria,2GNEW@201174|Actinobacteria,4DNCR@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
gnl|extdb|FAM1414-i1-1.1_001044	1146883.BLASA_1487	6.03e-11	63.9	2E4ST@1|root,32ZM5@2|Bacteria,2GSCH@201174|Actinobacteria,4ETEF@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
gnl|extdb|FAM1414-i1-1.1_001045	754252.PFREUD_12040	4.27e-293	800.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DPPT@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.90	ko:K00895	ko00010,ko00030,ko00051,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map01100,map01110,map01120,map01130	-	R00764,R02073	RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
gnl|extdb|FAM1414-i1-1.1_001047	754252.PFREUD_12060	1.33e-128	365.0	2EFFR@1|root,3398G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001048	754252.PFREUD_12070	3.96e-186	518.0	COG0568@1|root,COG0568@2|Bacteria	2|Bacteria	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086,ko:K03087,ko:K03093	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
gnl|extdb|FAM1414-i1-1.1_001050	754252.PFREUD_12090	6.4e-174	484.0	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
gnl|extdb|FAM1414-i1-1.1_001051	754252.PFREUD_12100	4.22e-60	185.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001052	754252.PFREUD_12110	0.0	945.0	COG0568@1|root,COG0568@2|Bacteria,2H4XN@201174|Actinobacteria	201174|Actinobacteria	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001053	754252.PFREUD_12120	1.04e-220	609.0	COG1397@1|root,COG1397@2|Bacteria,2HEZY@201174|Actinobacteria,4DQGC@85009|Propionibacteriales	201174|Actinobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
gnl|extdb|FAM1414-i1-1.1_001057	754252.PFREUD_12160	3.06e-201	557.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4DNQI@85009|Propionibacteriales	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
gnl|extdb|FAM1414-i1-1.1_001059	754252.PFREUD_12180	1.07e-120	345.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.85,5.4.2.11,5.4.2.12	ko:K01834,ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
gnl|extdb|FAM1414-i1-1.1_001060	754252.PFREUD_12190	3.18e-262	717.0	COG1270@1|root,COG1270@2|Bacteria,2GMB8@201174|Actinobacteria,4DNIT@85009|Propionibacteriales	201174|Actinobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
gnl|extdb|FAM1414-i1-1.1_001061	754252.PFREUD_12200	0.0	958.0	COG1492@1|root,COG1492@2|Bacteria,2GJ1W@201174|Actinobacteria,4DPU3@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
gnl|extdb|FAM1414-i1-1.1_001062	754252.PFREUD_12210	2.75e-148	416.0	COG2109@1|root,COG2109@2|Bacteria,2GNJQ@201174|Actinobacteria,4DNYI@85009|Propionibacteriales	201174|Actinobacteria	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2849c	CobA_CobO_BtuR
gnl|extdb|FAM1414-i1-1.1_001063	754252.PFREUD_12220	0.0	1708.0	COG0079@1|root,COG1797@1|root,COG0079@2|Bacteria,COG1797@2|Bacteria,2GJ3R@201174|Actinobacteria,4DN94@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	cobB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,CbiA,GATase_3
gnl|extdb|FAM1414-i1-1.1_001064	754252.PFREUD_12230	1.51e-161	452.0	COG2087@1|root,COG2087@2|Bacteria,2GM8Q@201174|Actinobacteria,4DQRD@85009|Propionibacteriales	201174|Actinobacteria	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU,Lactamase_B_2
gnl|extdb|FAM1414-i1-1.1_001065	754252.PFREUD_12240	1.96e-176	493.0	COG0368@1|root,COG0368@2|Bacteria,2GKM4@201174|Actinobacteria	201174|Actinobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
gnl|extdb|FAM1414-i1-1.1_001067	754252.PFREUD_12260	6.29e-182	507.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001068	754252.PFREUD_12270	0.0	1226.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4DQ2G@85009|Propionibacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3
gnl|extdb|FAM1414-i1-1.1_001069	754252.PFREUD_12280	0.0	904.0	COG1295@1|root,COG1295@2|Bacteria,2GN79@201174|Actinobacteria,4DS0K@85009|Propionibacteriales	201174|Actinobacteria	S	Virulence factor BrkB	yhjD	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
gnl|extdb|FAM1414-i1-1.1_001070	754252.PFREUD_12300	0.0	1924.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4DNP8@85009|Propionibacteriales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
gnl|extdb|FAM1414-i1-1.1_001071	754252.PFREUD_12310	1.51e-133	379.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4DPQ2@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
gnl|extdb|FAM1414-i1-1.1_001072	754252.PFREUD_12320	5.07e-103	298.0	COG1259@1|root,COG1259@2|Bacteria	2|Bacteria	K	PFAM Uncharacterised ACR, COG1259	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
gnl|extdb|FAM1414-i1-1.1_001073	754252.PFREUD_12330	1.05e-167	469.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4DQDI@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
gnl|extdb|FAM1414-i1-1.1_001074	754252.PFREUD_12340	5.39e-116	332.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4DR1A@85009|Propionibacteriales	201174|Actinobacteria	T	zinc-ribbon domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
gnl|extdb|FAM1414-i1-1.1_001075	754252.PFREUD_12350	1.76e-86	254.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4DR4B@85009|Propionibacteriales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
gnl|extdb|FAM1414-i1-1.1_001076	754252.PFREUD_12360	1.17e-164	461.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4DR07@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
gnl|extdb|FAM1414-i1-1.1_001077	754252.PFREUD_12370	7.7e-64	196.0	COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4DR0I@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1290)	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
gnl|extdb|FAM1414-i1-1.1_001080	754252.PFREUD_12400	3.04e-279	763.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4DNV1@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase Family 4	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
gnl|extdb|FAM1414-i1-1.1_001081	754252.PFREUD_12410	6.4e-215	592.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
gnl|extdb|FAM1414-i1-1.1_001082	754252.PFREUD_12420	1.39e-141	400.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4DP2F@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.11,2.7.8.5	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	-	R01801,R01802	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
gnl|extdb|FAM1414-i1-1.1_001083	754252.PFREUD_12430	4.95e-147	414.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4DQ7R@85009|Propionibacteriales	201174|Actinobacteria	FG	HIT domain	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
gnl|extdb|FAM1414-i1-1.1_001089	754252.PFREUD_12500	2.91e-192	534.0	COG2138@1|root,COG2138@2|Bacteria,2GS51@201174|Actinobacteria,4DQ03@85009|Propionibacteriales	201174|Actinobacteria	S	CbiX	cbiX	-	-	-	-	-	-	-	-	-	-	-	CbiX
gnl|extdb|FAM1414-i1-1.1_001090	754252.PFREUD_12510	1.74e-219	604.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4DNFS@85009|Propionibacteriales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
gnl|extdb|FAM1414-i1-1.1_001091	754252.PFREUD_12520	2.53e-115	329.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4DQU8@85009|Propionibacteriales	201174|Actinobacteria	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
gnl|extdb|FAM1414-i1-1.1_001092	754252.PFREUD_12530	4.67e-116	333.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria,4DR3S@85009|Propionibacteriales	201174|Actinobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
gnl|extdb|FAM1414-i1-1.1_001093	754252.PFREUD_12540	1.72e-146	412.0	2AIF4@1|root,318WM@2|Bacteria,2GK8R@201174|Actinobacteria,4DQE6@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3000
gnl|extdb|FAM1414-i1-1.1_001095	754252.PFREUD_12560	0.0	1320.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4DNP5@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
gnl|extdb|FAM1414-i1-1.1_001096	754252.PFREUD_12570	2e-119	341.0	2E8DB@1|root,332RT@2|Bacteria,2IHS0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001097	754252.PFREUD_12580	5.68e-68	205.0	COG4367@1|root,COG4367@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	DUF2316
gnl|extdb|FAM1414-i1-1.1_001098	754252.PFREUD_12590	0.0	1786.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DPP4@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
gnl|extdb|FAM1414-i1-1.1_001099	754252.PFREUD_12600	2.34e-306	838.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	kgtP	-	-	ko:K03761	-	-	-	-	ko00000,ko02000	2.A.1.6.2	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_001100	754252.PFREUD_12610	1.82e-258	707.0	COG0435@1|root,COG0435@2|Bacteria,2GIXK@201174|Actinobacteria,4DNXR@85009|Propionibacteriales	201174|Actinobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
gnl|extdb|FAM1414-i1-1.1_001102	754252.PFREUD_12640	2.72e-156	438.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
gnl|extdb|FAM1414-i1-1.1_001103	1171373.PACID_02490	1.55e-191	539.0	COG0435@1|root,COG0435@2|Bacteria,2GIXK@201174|Actinobacteria,4DNXR@85009|Propionibacteriales	201174|Actinobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N_2
gnl|extdb|FAM1414-i1-1.1_001106	754252.PFREUD_12690	0.0	1246.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4DP47@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid permease	ydaO	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
gnl|extdb|FAM1414-i1-1.1_001108	754252.PFREUD_12710	4.14e-154	433.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4DN0P@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-C domain	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
gnl|extdb|FAM1414-i1-1.1_001111	1122994.AUFR01000016_gene1863	3.26e-14	68.9	2DR0Y@1|root,339QH@2|Bacteria,2GWIF@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
gnl|extdb|FAM1414-i1-1.1_001112	754252.PFREUD_12750	3.5e-62	191.0	2ATJW@1|root,32RNQ@2|Bacteria,2I810@201174|Actinobacteria,4DR4Y@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
gnl|extdb|FAM1414-i1-1.1_001113	754252.PFREUD_12760	1.01e-292	802.0	28PUQ@1|root,2ZCFK@2|Bacteria,2GNQM@201174|Actinobacteria,4DR1M@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3071
gnl|extdb|FAM1414-i1-1.1_001114	754252.PFREUD_12770	1.71e-286	781.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4DNS7@85009|Propionibacteriales	201174|Actinobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
gnl|extdb|FAM1414-i1-1.1_001116	754252.PFREUD_12790	2.65e-272	743.0	COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
gnl|extdb|FAM1414-i1-1.1_001117	754252.PFREUD_12800	0.0	1590.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4DPNM@85009|Propionibacteriales	201174|Actinobacteria	L	DNA Topoisomerase IV	gyrA2	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
gnl|extdb|FAM1414-i1-1.1_001118	754252.PFREUD_12810	5.54e-214	591.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4DUY3@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
gnl|extdb|FAM1414-i1-1.1_001121	754252.PFREUD_12840	8.63e-226	622.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4DV68@85009|Propionibacteriales	201174|Actinobacteria	C	lactate/malate dehydrogenase, NAD binding domain	ldh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
gnl|extdb|FAM1414-i1-1.1_001122	754252.PFREUD_12850	2.61e-299	824.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DN2F@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
gnl|extdb|FAM1414-i1-1.1_001123	754252.PFREUD_12860	2.42e-210	582.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DNNR@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
gnl|extdb|FAM1414-i1-1.1_001124	762211.BSTEL_1136	2.47e-121	359.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CZWK@85004|Bifidobacteriales	201174|Actinobacteria	K	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
gnl|extdb|FAM1414-i1-1.1_001126	754252.PFREUD_12910	1.08e-213	589.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4DN4N@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
gnl|extdb|FAM1414-i1-1.1_001127	754252.PFREUD_12920	0.0	2591.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4DNBR@85009|Propionibacteriales	201174|Actinobacteria	L	ATP-dependent helicase hrpA	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
gnl|extdb|FAM1414-i1-1.1_001128	754252.PFREUD_12930	0.0	1781.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4DNF9@85009|Propionibacteriales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
gnl|extdb|FAM1414-i1-1.1_001129	754252.PFREUD_12940	2.32e-209	580.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4DPWX@85009|Propionibacteriales	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
gnl|extdb|FAM1414-i1-1.1_001130	754252.PFREUD_12960	1.37e-220	609.0	COG2390@1|root,COG2390@2|Bacteria,2GMIM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	HTH_23,HTH_28,MarR_2,Sigma70_r4,Sugar-bind
gnl|extdb|FAM1414-i1-1.1_001132	754252.PFREUD_12980	1.02e-314	857.0	COG3075@1|root,COG3075@2|Bacteria,2GMNS@201174|Actinobacteria	201174|Actinobacteria	E	Glycerol-3-phosphate dehydrogenase	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
gnl|extdb|FAM1414-i1-1.1_001134	754252.PFREUD_13000	1.18e-225	621.0	COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4DRYI@85009|Propionibacteriales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
gnl|extdb|FAM1414-i1-1.1_001135	754252.PFREUD_13010	0.0	1898.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4DP4H@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
gnl|extdb|FAM1414-i1-1.1_001136	754252.PFREUD_13020	1.87e-113	325.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4DQJU@85009|Propionibacteriales	201174|Actinobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
gnl|extdb|FAM1414-i1-1.1_001138	754252.PFREUD_13040	3.54e-193	536.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4DNCQ@85009|Propionibacteriales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
gnl|extdb|FAM1414-i1-1.1_001140	754252.PFREUD_13060	0.0	905.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4DNPS@85009|Propionibacteriales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
gnl|extdb|FAM1414-i1-1.1_001141	754252.PFREUD_13070	6.22e-206	568.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4DN7Z@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
gnl|extdb|FAM1414-i1-1.1_001142	754252.PFREUD_13080	1.24e-233	643.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4DP56@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
gnl|extdb|FAM1414-i1-1.1_001143	754252.PFREUD_13090	0.0	1017.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4DNBY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
gnl|extdb|FAM1414-i1-1.1_001145	754252.PFREUD_13110	3.35e-303	834.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4DQ4C@85009|Propionibacteriales	201174|Actinobacteria	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
gnl|extdb|FAM1414-i1-1.1_001146	754252.PFREUD_13120	7.6e-123	352.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria	201174|Actinobacteria	S	regulatory protein RecX	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
gnl|extdb|FAM1414-i1-1.1_001147	754252.PFREUD_13130	3.29e-242	668.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4DPDK@85009|Propionibacteriales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
gnl|extdb|FAM1414-i1-1.1_001148	754252.PFREUD_13140	2.68e-43	140.0	2AU8K@1|root,31JVT@2|Bacteria,2HZCZ@201174|Actinobacteria,4DS5N@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
gnl|extdb|FAM1414-i1-1.1_001149	754252.PFREUD_13150	0.0	3055.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4DPDX@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
gnl|extdb|FAM1414-i1-1.1_001150	754252.PFREUD_13160	5.01e-55	172.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,4DS8T@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_31
gnl|extdb|FAM1414-i1-1.1_001152	754252.PFREUD_13190	5.24e-150	422.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4DQPW@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
gnl|extdb|FAM1414-i1-1.1_001153	754252.PFREUD_13200	0.0	932.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,4DNHY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
gnl|extdb|FAM1414-i1-1.1_001154	754252.PFREUD_13210	0.0	1582.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4DN14@85009|Propionibacteriales	201174|Actinobacteria	D	Ftsk_gamma	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
gnl|extdb|FAM1414-i1-1.1_001155	754252.PFREUD_13220	3.84e-232	639.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DNV9@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
gnl|extdb|FAM1414-i1-1.1_001156	754252.PFREUD_13230	9.36e-171	477.0	COG1309@1|root,COG1309@2|Bacteria,2H5KV@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_001157	754252.PFREUD_13240	4.24e-248	680.0	28H6R@1|root,2Z7J3@2|Bacteria,2I9RC@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001158	754252.PFREUD_13250	2.04e-274	750.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
gnl|extdb|FAM1414-i1-1.1_001159	754252.PFREUD_13260	1.52e-195	541.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4DQUS@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
gnl|extdb|FAM1414-i1-1.1_001160	754252.PFREUD_13270	4.4e-144	405.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4DPSM@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2987c	Aconitase_C
gnl|extdb|FAM1414-i1-1.1_001161	754252.PFREUD_13280	0.0	932.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4DNZM@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
gnl|extdb|FAM1414-i1-1.1_001162	754252.PFREUD_13290	1.13e-161	454.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4DP77@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
gnl|extdb|FAM1414-i1-1.1_001165	754252.PFREUD_13320	6.04e-250	687.0	COG1266@1|root,COG1266@2|Bacteria,2GR9Y@201174|Actinobacteria,4DWVR@85009|Propionibacteriales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
gnl|extdb|FAM1414-i1-1.1_001166	754252.PFREUD_13330	2.34e-203	562.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4DPHV@85009|Propionibacteriales	201174|Actinobacteria	Q	Domain of unknown function (DUF2437)	fahA	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
gnl|extdb|FAM1414-i1-1.1_001167	754252.PFREUD_13340	0.0	1065.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4DNDJ@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
gnl|extdb|FAM1414-i1-1.1_001168	754252.PFREUD_13350	3.23e-273	746.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4DPRZ@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
gnl|extdb|FAM1414-i1-1.1_001169	754252.PFREUD_13360	1.13e-249	686.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4DPJF@85009|Propionibacteriales	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
gnl|extdb|FAM1414-i1-1.1_001171	1035308.AQYY01000002_gene1049	1.54e-12	73.9	29XDV@1|root,30J3Z@2|Bacteria,1W1G1@1239|Firmicutes,252S6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000933	754252.PFREUD_10770	0.0	970.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4DNB4@85009|Propionibacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
gnl|extdb|FAM1414-i1-1.1_000936	754252.PFREUD_10810	6.47e-260	712.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4DNDZ@85009|Propionibacteriales	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepE	-	3.4.13.9,3.5.3.3	ko:K01271,ko:K01274,ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
gnl|extdb|FAM1414-i1-1.1_000948	754252.PFREUD_10930	2.2e-174	487.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4DQB5@85009|Propionibacteriales	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
gnl|extdb|FAM1414-i1-1.1_001002	754252.PFREUD_11610	1.88e-170	477.0	COG3527@1|root,COG3527@2|Bacteria,2IBRH@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the alpha-acetolactate decarboxylase family	budA	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
gnl|extdb|FAM1414-i1-1.1_001017	754252.PFREUD_11760	1.04e-145	411.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4DPJU@85009|Propionibacteriales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
gnl|extdb|FAM1414-i1-1.1_001029	754252.PFREUD_11880	1.34e-196	546.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4DNGE@85009|Propionibacteriales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
gnl|extdb|FAM1414-i1-1.1_001032	754252.PFREUD_11910	0.0	1001.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4DQ56@85009|Propionibacteriales	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
gnl|extdb|FAM1414-i1-1.1_001037	754252.PFREUD_11960	2.36e-211	586.0	COG2984@1|root,COG2984@2|Bacteria,2GKNV@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter substrate-binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
gnl|extdb|FAM1414-i1-1.1_001049	754252.PFREUD_12080	0.0	1245.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4DN6K@85009|Propionibacteriales	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
gnl|extdb|FAM1414-i1-1.1_001055	537013.CLOSTMETH_02269	2.09e-23	92.4	COG2314@1|root,COG2314@2|Bacteria,1VNA3@1239|Firmicutes,24UCG@186801|Clostridia,3WMHZ@541000|Ruminococcaceae	186801|Clostridia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
gnl|extdb|FAM1414-i1-1.1_001058	754252.PFREUD_12170	0.0	989.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4DNDY@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
gnl|extdb|FAM1414-i1-1.1_001066	754252.PFREUD_12250	1.18e-121	350.0	COG1309@1|root,COG1309@2|Bacteria,2GQPK@201174|Actinobacteria,4DR62@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
gnl|extdb|FAM1414-i1-1.1_001078	754252.PFREUD_12380	4.95e-99	293.0	COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4DR0G@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
gnl|extdb|FAM1414-i1-1.1_001079	754252.PFREUD_12390	1.21e-138	393.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4DQ8M@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
gnl|extdb|FAM1414-i1-1.1_001084	754252.PFREUD_12440	0.0	1359.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4DN38@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
gnl|extdb|FAM1414-i1-1.1_001094	754252.PFREUD_12550	1.84e-313	853.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4DNGR@85009|Propionibacteriales	201174|Actinobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
gnl|extdb|FAM1414-i1-1.1_001105	754252.PFREUD_12680	6.62e-286	780.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4DN2V@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
gnl|extdb|FAM1414-i1-1.1_001107	754252.PFREUD_12700	7.65e-150	422.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,4DNXX@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
gnl|extdb|FAM1414-i1-1.1_001109	754252.PFREUD_12720	2.29e-80	238.0	COG1200@1|root,COG1200@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001110	754252.PFREUD_12730	3.93e-151	428.0	28J4D@1|root,2Z90C@2|Bacteria,2GJYC@201174|Actinobacteria,4DRF5@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
gnl|extdb|FAM1414-i1-1.1_001115	754252.PFREUD_12780	9.22e-141	397.0	29850@1|root,2ZVAX@2|Bacteria,2GKR1@201174|Actinobacteria,4DQC6@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001119	754252.PFREUD_12820	0.0	1319.0	COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,4DN70@85009|Propionibacteriales	201174|Actinobacteria	L	TopoisomeraseII	gyrB2	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
gnl|extdb|FAM1414-i1-1.1_001120	754252.PFREUD_12830	7.06e-39	129.0	2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001125	754252.PFREUD_12900	1.02e-239	661.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4DPIZ@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
gnl|extdb|FAM1414-i1-1.1_001131	754252.PFREUD_12970	1.98e-301	824.0	COG0247@1|root,COG0247@2|Bacteria,2H9RN@201174|Actinobacteria	201174|Actinobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	1.1.5.3	ko:K00113,ko:K18930	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
gnl|extdb|FAM1414-i1-1.1_001133	754252.PFREUD_12990	0.0	1084.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
gnl|extdb|FAM1414-i1-1.1_001139	754252.PFREUD_13050	0.0	1301.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,4DN8C@85009|Propionibacteriales	201174|Actinobacteria	KL	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
gnl|extdb|FAM1414-i1-1.1_001144	754252.PFREUD_13100	2.46e-166	466.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DNTI@85009|Propionibacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	gluA	-	3.6.3.21	ko:K02028,ko:K10008	ko02010,map02010	M00233,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.9	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001151	754252.PFREUD_13180	6.97e-99	288.0	COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4DS1E@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
gnl|extdb|FAM1414-i1-1.1_001104	888439.HMPREF9240_00565	1.91e-17	76.3	28ZZN@1|root,2ZMPZ@2|Bacteria,2GXJY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001411	754252.PFREUD_24680	3.1e-118	345.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DUKR@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve,rve_3
gnl|extdb|FAM1414-i1-1.1_001412	754252.PFREUD_20730	3.56e-182	506.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,4DQJ7@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
gnl|extdb|FAM1414-i1-1.1_001413	754252.PFREUD_20720	8.86e-244	669.0	COG2894@1|root,COG2894@2|Bacteria,2I56Y@201174|Actinobacteria,4DWGF@85009|Propionibacteriales	201174|Actinobacteria	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	ParA
gnl|extdb|FAM1414-i1-1.1_001414	754252.PFREUD_20710	2.68e-274	750.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4DN5K@85009|Propionibacteriales	201174|Actinobacteria	U	Type II/IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
gnl|extdb|FAM1414-i1-1.1_001415	754252.PFREUD_20700	4.78e-179	499.0	COG4965@1|root,COG4965@2|Bacteria	2|Bacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
gnl|extdb|FAM1414-i1-1.1_001416	754252.PFREUD_20690	1.04e-164	462.0	COG2064@1|root,COG2064@2|Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein F	gspF	-	-	ko:K12510,ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
gnl|extdb|FAM1414-i1-1.1_001417	754252.PFREUD_20680	1.61e-47	160.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	yisX	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
gnl|extdb|FAM1414-i1-1.1_001419	754252.PFREUD_20660	2.51e-98	286.0	2EGB2@1|root,33A2X@2|Bacteria,2GT7C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
gnl|extdb|FAM1414-i1-1.1_001420	313589.JNB_09744	2.92e-07	53.1	2DRBM@1|root,33B4F@2|Bacteria,2HZS2@201174|Actinobacteria,4FJH9@85021|Intrasporangiaceae	201174|Actinobacteria	S	TIGRFAM helicase secretion neighborhood TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
gnl|extdb|FAM1414-i1-1.1_001421	754252.PFREUD_20640	1.54e-51	163.0	2DR18@1|root,339RQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001422	754252.PFREUD_20630	2.61e-160	454.0	COG3381@1|root,COG3381@2|Bacteria,2ISXF@201174|Actinobacteria	201174|Actinobacteria	S	PFAM cytoplasmic chaperone TorD	-	-	-	ko:K03533	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.4	-	-	Nitrate_red_del
gnl|extdb|FAM1414-i1-1.1_001423	754252.PFREUD_20620	2.06e-279	765.0	COG1143@1|root,COG1143@2|Bacteria,2GRKW@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
gnl|extdb|FAM1414-i1-1.1_001425	754252.PFREUD_20600	8.83e-170	472.0	COG0437@1|root,COG0437@2|Bacteria,2H0W0@201174|Actinobacteria,4DVEF@85009|Propionibacteriales	201174|Actinobacteria	C	4Fe-4S binding domain	-	-	-	ko:K07307,ko:K07311	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_3,Fer4_4
gnl|extdb|FAM1414-i1-1.1_001426	754252.PFREUD_20590	1.1e-230	636.0	COG3302@1|root,COG3302@2|Bacteria,2GV8F@201174|Actinobacteria	201174|Actinobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K07308	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	DmsC
gnl|extdb|FAM1414-i1-1.1_001427	754252.PFREUD_20580	0.0	1619.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4DNQG@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
gnl|extdb|FAM1414-i1-1.1_001428	754252.PFREUD_20570	0.0	1011.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,4DNCS@85009|Propionibacteriales	201174|Actinobacteria	J	Methyltransferase small domain	rsmC	-	-	-	-	-	-	-	-	-	-	-	MTS
gnl|extdb|FAM1414-i1-1.1_001429	754252.PFREUD_20560	0.0	1710.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4DN7K@85009|Propionibacteriales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
gnl|extdb|FAM1414-i1-1.1_001430	767029.HMPREF9154_2697	2.46e-36	147.0	COG3025@1|root,COG3025@2|Bacteria	2|Bacteria	S	triphosphatase activity	cyaA6	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.1.25	ko:K18446	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,CYTH
gnl|extdb|FAM1414-i1-1.1_001431	754252.PFREUD_20540	1.45e-149	421.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4DNXP@85009|Propionibacteriales	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
gnl|extdb|FAM1414-i1-1.1_001433	754252.PFREUD_20520	9.1e-270	753.0	COG2259@1|root,COG2259@2|Bacteria,2GV27@201174|Actinobacteria	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
gnl|extdb|FAM1414-i1-1.1_001434	754252.PFREUD_20510	1.02e-222	617.0	COG1774@1|root,COG1774@2|Bacteria,2HYDT@201174|Actinobacteria	201174|Actinobacteria	S	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
gnl|extdb|FAM1414-i1-1.1_001436	754252.PFREUD_20480	7.33e-186	518.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
gnl|extdb|FAM1414-i1-1.1_001437	754252.PFREUD_20470	7.67e-259	721.0	COG0577@1|root,COG0577@2|Bacteria,2GMH5@201174|Actinobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
gnl|extdb|FAM1414-i1-1.1_001438	754252.PFREUD_20460	0.0	922.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	cycA	-	-	ko:K03293,ko:K11737	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.7	-	-	AA_permease
gnl|extdb|FAM1414-i1-1.1_001439	754252.PFREUD_20440	0.0	894.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4DP12@85009|Propionibacteriales	201174|Actinobacteria	E	amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
gnl|extdb|FAM1414-i1-1.1_001440	754252.PFREUD_20430	2.46e-70	212.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4DR0Z@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the P(II) protein family	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
gnl|extdb|FAM1414-i1-1.1_001441	754252.PFREUD_20420	1.19e-315	861.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4DNW9@85009|Propionibacteriales	201174|Actinobacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iNJ661.Rv2920c	Ammonium_transp
gnl|extdb|FAM1414-i1-1.1_001442	754252.PFREUD_20410	1.58e-240	662.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
gnl|extdb|FAM1414-i1-1.1_001443	754252.PFREUD_20400	7.91e-216	595.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
gnl|extdb|FAM1414-i1-1.1_001444	754252.PFREUD_20390	2.49e-123	352.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
gnl|extdb|FAM1414-i1-1.1_001446	754252.PFREUD_20370	2.26e-134	380.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4DQYI@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
gnl|extdb|FAM1414-i1-1.1_001447	754252.PFREUD_20360	1.63e-312	853.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4DN2Y@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
gnl|extdb|FAM1414-i1-1.1_001448	754252.PFREUD_20350	8.43e-261	714.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4DNQY@85009|Propionibacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
gnl|extdb|FAM1414-i1-1.1_001449	754252.PFREUD_20340	1.79e-222	615.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4DQ41@85009|Propionibacteriales	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
gnl|extdb|FAM1414-i1-1.1_001450	754252.PFREUD_20330	7.67e-124	353.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4DN1D@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
gnl|extdb|FAM1414-i1-1.1_001451	754252.PFREUD_20320	0.0	1566.0	COG0507@1|root,COG0507@2|Bacteria	2|Bacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	Herpes_Helicase,PIF1,UvrD_C_2
gnl|extdb|FAM1414-i1-1.1_001453	754252.PFREUD_20300	2.02e-67	207.0	COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria,4DRRW@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
gnl|extdb|FAM1414-i1-1.1_001454	754252.PFREUD_20290	6.95e-204	564.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4DPQM@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
gnl|extdb|FAM1414-i1-1.1_001456	754252.PFREUD_20270	2.13e-129	367.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4DQ88@85009|Propionibacteriales	201174|Actinobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
gnl|extdb|FAM1414-i1-1.1_001458	754252.PFREUD_20260	9.17e-70	210.0	2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria	201174|Actinobacteria	S	pathogenesis	lsr	-	-	-	-	-	-	-	-	-	-	-	Lsr2
gnl|extdb|FAM1414-i1-1.1_001459	754252.PFREUD_20250	0.0	1608.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4DPBH@85009|Propionibacteriales	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
gnl|extdb|FAM1414-i1-1.1_001460	1214242.B446_00400	5.38e-05	50.8	COG0515@1|root,COG0515@2|Bacteria,2IK8K@201174|Actinobacteria	201174|Actinobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
gnl|extdb|FAM1414-i1-1.1_001461	754252.PFREUD_20230	1.43e-173	484.0	COG0710@1|root,COG0710@2|Bacteria,2GREB@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
gnl|extdb|FAM1414-i1-1.1_001462	754252.PFREUD_20210	3.87e-136	385.0	COG0572@1|root,COG0572@2|Bacteria,2HQC8@201174|Actinobacteria,4DRP4@85009|Propionibacteriales	201174|Actinobacteria	F	uridine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,Cytidylate_kin
gnl|extdb|FAM1414-i1-1.1_001463	754252.PFREUD_20200	2.76e-183	511.0	COG0619@1|root,COG0619@2|Bacteria,2IDC9@201174|Actinobacteria	201174|Actinobacteria	P	cobalt transport	ykoC	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
gnl|extdb|FAM1414-i1-1.1_001464	754252.PFREUD_20190	0.0	1008.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4DT5R@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
gnl|extdb|FAM1414-i1-1.1_001465	754252.PFREUD_20180	2.31e-141	400.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria	201174|Actinobacteria	S	membrane	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
gnl|extdb|FAM1414-i1-1.1_001467	754252.PFREUD_20160	7.31e-247	679.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4DNMZ@85009|Propionibacteriales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
gnl|extdb|FAM1414-i1-1.1_001468	754252.PFREUD_20150	0.0	889.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DNF3@85009|Propionibacteriales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
gnl|extdb|FAM1414-i1-1.1_001469	754252.PFREUD_20140	6.97e-157	439.0	2DC18@1|root,2ZCCT@2|Bacteria,2IBBW@201174|Actinobacteria,4DUJG@85009|Propionibacteriales	201174|Actinobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
gnl|extdb|FAM1414-i1-1.1_001470	754252.PFREUD_20130	3.09e-209	577.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria,4DMZR@85009|Propionibacteriales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
gnl|extdb|FAM1414-i1-1.1_001472	754252.PFREUD_20110	3.95e-153	431.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
gnl|extdb|FAM1414-i1-1.1_001473	754252.PFREUD_20100	9.61e-246	675.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4DNGU@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
gnl|extdb|FAM1414-i1-1.1_001474	754252.PFREUD_20090	3.03e-165	466.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4DNEJ@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
gnl|extdb|FAM1414-i1-1.1_001475	196162.Noca_0485	2.71e-08	50.1	2B42S@1|root,31WTB@2|Bacteria,2GXWF@201174|Actinobacteria,4DST4@85009|Propionibacteriales	201174|Actinobacteria	S	Mitochondrial domain of unknown function (DUF1713)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1713
gnl|extdb|FAM1414-i1-1.1_001476	754252.PFREUD_20070	0.0	1036.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4DNP0@85009|Propionibacteriales	201174|Actinobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
gnl|extdb|FAM1414-i1-1.1_001477	754252.PFREUD_20060	3.18e-161	451.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4DPM9@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
gnl|extdb|FAM1414-i1-1.1_001478	754252.PFREUD_20050	0.0	1003.0	COG1249@1|root,COG1249@2|Bacteria,2GNSR@201174|Actinobacteria,4DPYH@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	mtr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657	1.8.1.15	ko:K17883	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
gnl|extdb|FAM1414-i1-1.1_001479	754252.PFREUD_20040	6.5e-248	686.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4DQDD@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
gnl|extdb|FAM1414-i1-1.1_001481	754252.PFREUD_20020	3.04e-105	304.0	2DMHQ@1|root,32RMG@2|Bacteria,2IQ7H@201174|Actinobacteria	201174|Actinobacteria	S	Arsenical resistance operon trans-acting repressor	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
gnl|extdb|FAM1414-i1-1.1_001482	754252.PFREUD_20010	4.73e-85	250.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,LMWPc
gnl|extdb|FAM1414-i1-1.1_001483	754252.PFREUD_19990	6.59e-93	272.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4DQUH@85009|Propionibacteriales	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
gnl|extdb|FAM1414-i1-1.1_001484	754252.PFREUD_19980	1.65e-183	511.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4DN0B@85009|Propionibacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001485	754252.PFREUD_19970	5.64e-257	707.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4DPD3@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_001486	754252.PFREUD_19960	4.56e-219	606.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4DNZF@85009|Propionibacteriales	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_001487	754252.PFREUD_19950	7.2e-241	664.0	COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,4DPFF@85009|Propionibacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
gnl|extdb|FAM1414-i1-1.1_001488	754252.PFREUD_19940	1.42e-216	597.0	COG0494@1|root,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4DQI9@85009|Propionibacteriales	201174|Actinobacteria	L	Phosphoglycerate mutase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
gnl|extdb|FAM1414-i1-1.1_001489	754252.PFREUD_19930	0.0	1431.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4DNIH@85009|Propionibacteriales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
gnl|extdb|FAM1414-i1-1.1_001490	754252.PFREUD_19920	1.61e-229	631.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4DQJC@85009|Propionibacteriales	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
gnl|extdb|FAM1414-i1-1.1_001491	754252.PFREUD_19910	1.45e-238	656.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4DQX1@85009|Propionibacteriales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
gnl|extdb|FAM1414-i1-1.1_001492	754252.PFREUD_19900	2.24e-181	503.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD,Cupin_2
gnl|extdb|FAM1414-i1-1.1_001493	754252.PFREUD_19890	3.88e-175	489.0	COG2084@1|root,COG2084@2|Bacteria,2IE00@201174|Actinobacteria	201174|Actinobacteria	I	NAD binding domain of 6-phosphogluconate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_2
gnl|extdb|FAM1414-i1-1.1_001494	754252.PFREUD_19880	2.62e-262	718.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4DNQF@85009|Propionibacteriales	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
gnl|extdb|FAM1414-i1-1.1_001496	754252.PFREUD_19870	1.45e-157	441.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4DN15@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
gnl|extdb|FAM1414-i1-1.1_001497	754252.PFREUD_19860	2.12e-97	283.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4DQK6@85009|Propionibacteriales	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
gnl|extdb|FAM1414-i1-1.1_001499	754252.PFREUD_19830	8.54e-129	364.0	COG4044@1|root,COG4044@2|Bacteria,2GKGF@201174|Actinobacteria,4DQW9@85009|Propionibacteriales	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1794
gnl|extdb|FAM1414-i1-1.1_001500	754252.PFREUD_19820	5.23e-257	704.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4DN39@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
gnl|extdb|FAM1414-i1-1.1_001501	754252.PFREUD_19810	0.0	1234.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4DP68@85009|Propionibacteriales	201174|Actinobacteria	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
gnl|extdb|FAM1414-i1-1.1_001502	754252.PFREUD_19790	0.0	1700.0	COG4932@1|root,COG4932@2|Bacteria,2GJU9@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
gnl|extdb|FAM1414-i1-1.1_001503	1283287.KB822575_gene650	5.94e-62	213.0	COG4932@1|root,COG4932@2|Bacteria,2IE6W@201174|Actinobacteria	201174|Actinobacteria	M	Lpxtg-motif cell wall anchor domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
gnl|extdb|FAM1414-i1-1.1_001504	1238186.AOCN01000011_gene1362	1.1e-24	106.0	COG4932@1|root,COG4932@2|Bacteria,2I9ZQ@201174|Actinobacteria	201174|Actinobacteria	M	LPXTG cell wall anchor motif	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,GramPos_pilinD1,Gram_pos_anchor
gnl|extdb|FAM1414-i1-1.1_001506	754252.PFREUD_19740	2.47e-223	615.0	COG3764@1|root,COG3764@2|Bacteria,2HUS9@201174|Actinobacteria,4DVWE@85009|Propionibacteriales	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
gnl|extdb|FAM1414-i1-1.1_001507	754252.PFREUD_19730	1.68e-145	410.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4DPRI@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
gnl|extdb|FAM1414-i1-1.1_001512	754252.PFREUD_19680	0.0	955.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4DN3N@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-C domain	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
gnl|extdb|FAM1414-i1-1.1_001513	1122994.AUFR01000007_gene1021	3.87e-34	126.0	2E1BJ@1|root,32WRF@2|Bacteria,2GXNF@201174|Actinobacteria	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
gnl|extdb|FAM1414-i1-1.1_001514	754252.PFREUD_19660	4.82e-78	232.0	COG1918@1|root,COG1918@2|Bacteria,2GX6H@201174|Actinobacteria,4DVX5@85009|Propionibacteriales	201174|Actinobacteria	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
gnl|extdb|FAM1414-i1-1.1_001516	754252.PFREUD_19640	8.26e-136	384.0	COG0694@1|root,COG0694@2|Bacteria,2IRPN@201174|Actinobacteria,4DVEH@85009|Propionibacteriales	201174|Actinobacteria	O	NifU-like domain	-	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	NifU
gnl|extdb|FAM1414-i1-1.1_001517	754252.PFREUD_19630	5.4e-277	757.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4DQ3A@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
gnl|extdb|FAM1414-i1-1.1_001518	754252.PFREUD_19620	7.62e-312	863.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DQTY@85009|Propionibacteriales	201174|Actinobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
gnl|extdb|FAM1414-i1-1.1_001519	754252.PFREUD_19610	0.0	1075.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DNY6@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
gnl|extdb|FAM1414-i1-1.1_001520	754252.PFREUD_19600	0.0	912.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4DP0A@85009|Propionibacteriales	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
gnl|extdb|FAM1414-i1-1.1_001521	754252.PFREUD_19590	0.0	875.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4DPN4@85009|Propionibacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
gnl|extdb|FAM1414-i1-1.1_001523	754252.PFREUD_19570	3.4e-103	299.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
gnl|extdb|FAM1414-i1-1.1_001524	754252.PFREUD_19560	1.33e-167	468.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4DQ6H@85009|Propionibacteriales	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
gnl|extdb|FAM1414-i1-1.1_001525	754252.PFREUD_19550	1.33e-95	278.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4DRIP@85009|Propionibacteriales	201174|Actinobacteria	CO	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
gnl|extdb|FAM1414-i1-1.1_001526	754252.PFREUD_19540	0.0	1201.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
gnl|extdb|FAM1414-i1-1.1_001528	1151126.AQYI01000002_gene244	7.14e-14	75.9	2ANEZ@1|root,31DDM@2|Bacteria,2IARS@201174|Actinobacteria,4FP0Y@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001529	754252.PFREUD_19510	6.23e-266	729.0	2ANEZ@1|root,31DDM@2|Bacteria,2IARS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001530	754252.PFREUD_19500	8.1e-303	824.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
gnl|extdb|FAM1414-i1-1.1_001532	754252.PFREUD_19480	2.5e-52	165.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183,ko:K11189	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PTS-HPr
gnl|extdb|FAM1414-i1-1.1_001534	754252.PFREUD_19460	3.04e-80	238.0	COG1188@1|root,COG1188@2|Bacteria,2IQ6F@201174|Actinobacteria,4DV0F@85009|Propionibacteriales	201174|Actinobacteria	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
gnl|extdb|FAM1414-i1-1.1_001535	754252.PFREUD_19450	2.79e-159	447.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4DQJF@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_001537	754252.PFREUD_19430	1.29e-95	279.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4DQIS@85009|Propionibacteriales	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	yabJ	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
gnl|extdb|FAM1414-i1-1.1_001538	1171373.PACID_29150	3.77e-24	92.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria,4DS7G@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
gnl|extdb|FAM1414-i1-1.1_001539	754252.PFREUD_19410	7.09e-78	232.0	2CC1Y@1|root,32TCV@2|Bacteria,2IQEP@201174|Actinobacteria,4DRQS@85009|Propionibacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB4	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0030312,GO:0043254,GO:0044087,GO:0044464,GO:0047134,GO:0048037,GO:0050789,GO:0050794,GO:0051128,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071944,GO:0090034,GO:0097159,GO:1901363	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
gnl|extdb|FAM1414-i1-1.1_001540	754252.PFREUD_19400	0.0	1429.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4DPA4@85009|Propionibacteriales	201174|Actinobacteria	M	Transglycosylase	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
gnl|extdb|FAM1414-i1-1.1_001543	754252.PFREUD_19370	0.0	995.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.12	ko:K00694,ko:K00786	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_tranf_2_3,Glyco_trans_2_3
gnl|extdb|FAM1414-i1-1.1_001546	754252.PFREUD_19350	0.0	932.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4DNWA@85009|Propionibacteriales	201174|Actinobacteria	Q	Multicopper oxidase	-	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
gnl|extdb|FAM1414-i1-1.1_001548	1285583.CCASEI_12085	6.66e-41	143.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,22RBI@1653|Corynebacteriaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
gnl|extdb|FAM1414-i1-1.1_001550	754252.PFREUD_19310	2.33e-238	655.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria	201174|Actinobacteria	F	nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
gnl|extdb|FAM1414-i1-1.1_001551	754252.PFREUD_19300	0.0	980.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DNGV@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldB	-	-	-	-	-	-	-	-	-	-	-	Aldedh
gnl|extdb|FAM1414-i1-1.1_001553	754252.PFREUD_19280	0.0	869.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4DNMU@85009|Propionibacteriales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
gnl|extdb|FAM1414-i1-1.1_001554	754252.PFREUD_19270	0.0	956.0	COG0531@1|root,COG0531@2|Bacteria,2GMTD@201174|Actinobacteria,4DQSQ@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c_2,SpoIIE
gnl|extdb|FAM1414-i1-1.1_001555	754252.PFREUD_19260	0.0	909.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,4DU4P@85009|Propionibacteriales	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
gnl|extdb|FAM1414-i1-1.1_001556	754252.PFREUD_19250	0.0	1613.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4DN44@85009|Propionibacteriales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
gnl|extdb|FAM1414-i1-1.1_001558	754252.PFREUD_19230	3.68e-228	627.0	COG0421@1|root,COG0421@2|Bacteria,2GN8I@201174|Actinobacteria,4DQ70@85009|Propionibacteriales	201174|Actinobacteria	E	spermidine synthase	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Spermine_synth
gnl|extdb|FAM1414-i1-1.1_001559	754252.PFREUD_19210	1.07e-137	390.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
gnl|extdb|FAM1414-i1-1.1_001560	754252.PFREUD_19200	1.27e-123	353.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
gnl|extdb|FAM1414-i1-1.1_001565	754252.PFREUD_19150	7.33e-248	680.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4DPKE@85009|Propionibacteriales	201174|Actinobacteria	G	Fructose-bisphosphate aldolase class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
gnl|extdb|FAM1414-i1-1.1_001567	754252.PFREUD_19130	7.03e-270	739.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
gnl|extdb|FAM1414-i1-1.1_001568	754252.PFREUD_19120	5.09e-250	693.0	2DYWR@1|root,34BGI@2|Bacteria,2I6UH@201174|Actinobacteria	201174|Actinobacteria	S	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
gnl|extdb|FAM1414-i1-1.1_001569	754252.PFREUD_19110	0.0	1033.0	COG0477@1|root,COG0477@2|Bacteria,2I77C@201174|Actinobacteria	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K06609	-	-	-	-	ko00000,ko02000	2.A.1.1.26	-	-	Sugar_tr
gnl|extdb|FAM1414-i1-1.1_001570	754252.PFREUD_19100	0.0	1005.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4DNVW@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	mmsA	GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
gnl|extdb|FAM1414-i1-1.1_001571	754252.PFREUD_19090	0.0	1255.0	COG3962@1|root,COG3962@2|Bacteria,2GMCJ@201174|Actinobacteria,4DQ59@85009|Propionibacteriales	201174|Actinobacteria	E	Thiamine pyrophosphate enzyme, central domain	iolD	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
gnl|extdb|FAM1414-i1-1.1_001573	754252.PFREUD_19070	1.25e-202	561.0	COG1830@1|root,COG1830@2|Bacteria,2GKTN@201174|Actinobacteria,4DN9P@85009|Propionibacteriales	201174|Actinobacteria	G	deoxyribose-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001574	754252.PFREUD_19060	5.94e-237	651.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria,4DNFD@85009|Propionibacteriales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
gnl|extdb|FAM1414-i1-1.1_001575	754252.PFREUD_19050	1.62e-174	487.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4DQMB@85009|Propionibacteriales	201174|Actinobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
gnl|extdb|FAM1414-i1-1.1_001576	754252.PFREUD_19040	1.57e-258	708.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4DTCS@85009|Propionibacteriales	201174|Actinobacteria	H	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
gnl|extdb|FAM1414-i1-1.1_001577	754252.PFREUD_19030	7.75e-233	641.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DUJU@85009|Propionibacteriales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	idhA	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
gnl|extdb|FAM1414-i1-1.1_001579	754252.PFREUD_19010	3.85e-227	626.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria	201174|Actinobacteria	G	dehydratase	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
gnl|extdb|FAM1414-i1-1.1_001580	754252.PFREUD_19000	8.42e-135	382.0	COG1279@1|root,COG1279@2|Bacteria,2IHQ2@201174|Actinobacteria,4DQJE@85009|Propionibacteriales	201174|Actinobacteria	S	LysE type translocator	lysE	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822	-	ko:K06895	-	-	-	-	ko00000,ko02000	2.A.75.1	-	-	LysE
gnl|extdb|FAM1414-i1-1.1_001581	754252.PFREUD_18990	0.0	1212.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DN1H@85009|Propionibacteriales	201174|Actinobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
gnl|extdb|FAM1414-i1-1.1_001582	754252.PFREUD_18980	0.0	1311.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4DQH7@85009|Propionibacteriales	201174|Actinobacteria	E	Asparagine synthase	asnB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
gnl|extdb|FAM1414-i1-1.1_001583	754252.PFREUD_18970	8.51e-286	782.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4DPDT@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
gnl|extdb|FAM1414-i1-1.1_001584	754252.PFREUD_18960	1.65e-213	590.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4DN1M@85009|Propionibacteriales	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
gnl|extdb|FAM1414-i1-1.1_001585	754252.PFREUD_18950	0.0	1178.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,4DP2Q@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
gnl|extdb|FAM1414-i1-1.1_001586	754252.PFREUD_18940	8.99e-277	756.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
gnl|extdb|FAM1414-i1-1.1_001587	754252.PFREUD_18930	0.0	934.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
gnl|extdb|FAM1414-i1-1.1_001588	754252.PFREUD_18920	5e-252	691.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,4DNBP@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
gnl|extdb|FAM1414-i1-1.1_001589	754252.PFREUD_18910	1.07e-236	651.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4DNVG@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
gnl|extdb|FAM1414-i1-1.1_001590	754252.PFREUD_18900	0.0	899.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4DPB8@85009|Propionibacteriales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K18926	-	M00715	-	-	ko00000,ko00002,ko02000	2.A.1.3.30	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_001591	754252.PFREUD_18890	2.79e-165	462.0	COG1309@1|root,COG1309@2|Bacteria,2GJXV@201174|Actinobacteria,4DWPP@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
gnl|extdb|FAM1414-i1-1.1_001592	754252.PFREUD_18880	9.43e-317	863.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4DNRS@85009|Propionibacteriales	201174|Actinobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
gnl|extdb|FAM1414-i1-1.1_001593	754252.PFREUD_18870	0.0	1008.0	COG5016@1|root,COG5016@2|Bacteria,2IASR@201174|Actinobacteria,4DWP2@85009|Propionibacteriales	201174|Actinobacteria	C	Conserved carboxylase domain	oadA	-	2.1.3.1	ko:K03416	ko00640,map00640	-	R00353,R00930	RC00040,RC00097	ko00000,ko00001,ko01000	-	-	-	HMGL-like,PYC_OADA
gnl|extdb|FAM1414-i1-1.1_001594	754252.PFREUD_18860	0.0	1030.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	mmdA	-	2.1.3.1	ko:K17489	ko00640,map00640	-	R00353	RC00040	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
gnl|extdb|FAM1414-i1-1.1_001595	1292373.H640_07489	9.49e-27	100.0	2EJZC@1|root,33DPX@2|Bacteria	2|Bacteria	-	-	-	-	2.1.3.1	ko:K17489	ko00640,map00640	-	R00353	RC00040	ko00000,ko00001,ko01000	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001596	754252.PFREUD_18840	2.53e-43	145.0	COG1038@1|root,COG1038@2|Bacteria	2|Bacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	yngHB	-	2.1.3.1,6.4.1.1	ko:K01958,ko:K02160,ko:K17490	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376	R00344,R00353,R00742	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
gnl|extdb|FAM1414-i1-1.1_001597	754252.PFREUD_18830	5.85e-171	478.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4DPFM@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	adh_short
gnl|extdb|FAM1414-i1-1.1_001598	754252.PFREUD_18820	1.28e-172	481.0	COG1309@1|root,COG1309@2|Bacteria,2HFX1@201174|Actinobacteria,4DRU7@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
gnl|extdb|FAM1414-i1-1.1_001599	754252.PFREUD_18810	1.06e-183	510.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4DND2@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
gnl|extdb|FAM1414-i1-1.1_001600	754252.PFREUD_18800	2.21e-155	436.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4DQEB@85009|Propionibacteriales	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
gnl|extdb|FAM1414-i1-1.1_001602	754252.PFREUD_18780	1.56e-155	437.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4DNN6@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
gnl|extdb|FAM1414-i1-1.1_001603	754252.PFREUD_18770	2.37e-105	305.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4DN6V@85009|Propionibacteriales	201174|Actinobacteria	K	CarD-like/TRCF domain	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
gnl|extdb|FAM1414-i1-1.1_001604	754252.PFREUD_18760	3.67e-160	450.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4DS1C@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
gnl|extdb|FAM1414-i1-1.1_001606	754252.PFREUD_18740	0.0	957.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4DPXC@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
gnl|extdb|FAM1414-i1-1.1_001607	754252.PFREUD_18730	4.91e-239	658.0	COG0252@1|root,COG0252@2|Bacteria	2|Bacteria	EJ	asparaginase activity	ansA	GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0033345,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_1961,iSF_1195.SF1456,iS_1188.S1571,iYL1228.KPN_01203	Asparaginase
gnl|extdb|FAM1414-i1-1.1_001610	754252.PFREUD_18690	1.52e-212	588.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4DNYC@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
gnl|extdb|FAM1414-i1-1.1_001611	754252.PFREUD_18680	0.0	969.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4DP8C@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
gnl|extdb|FAM1414-i1-1.1_001612	754252.PFREUD_18670	4.15e-237	654.0	COG2186@1|root,COG2186@2|Bacteria,2GZJA@201174|Actinobacteria,4DV1Q@85009|Propionibacteriales	201174|Actinobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
gnl|extdb|FAM1414-i1-1.1_001613	754252.PFREUD_18660	0.0	1061.0	COG1620@1|root,COG1620@2|Bacteria,2GIUF@201174|Actinobacteria,4DPUA@85009|Propionibacteriales	201174|Actinobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
gnl|extdb|FAM1414-i1-1.1_001614	754252.PFREUD_18650	4.9e-199	550.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4DNWX@85009|Propionibacteriales	201174|Actinobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
gnl|extdb|FAM1414-i1-1.1_001615	754252.PFREUD_18640	0.0	1042.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4DQ12@85009|Propionibacteriales	201174|Actinobacteria	C	LUD domain	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
gnl|extdb|FAM1414-i1-1.1_001616	754252.PFREUD_18630	3.98e-150	422.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria,4DRME@85009|Propionibacteriales	201174|Actinobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
gnl|extdb|FAM1414-i1-1.1_001618	754252.PFREUD_18600	0.0	924.0	COG3642@1|root,COG3642@2|Bacteria,2GIX0@201174|Actinobacteria,4DNTH@85009|Propionibacteriales	201174|Actinobacteria	T	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
gnl|extdb|FAM1414-i1-1.1_001619	754252.PFREUD_18590	1.83e-278	762.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DNK6@85009|Propionibacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.48	ko:K01739,ko:K21173	ko00270,ko00450,ko00920,ko01059,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01059,map01100,map01110,map01130,map01230	M00017,M00825	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
gnl|extdb|FAM1414-i1-1.1_001620	754252.PFREUD_18580	5.7e-260	712.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DN4V@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	msiK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
gnl|extdb|FAM1414-i1-1.1_001621	754252.PFREUD_18570	0.0	932.0	COG1760@1|root,COG1760@2|Bacteria,2GJPA@201174|Actinobacteria,4DPVP@85009|Propionibacteriales	201174|Actinobacteria	E	Serine dehydratase beta chain	sdaA	GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
gnl|extdb|FAM1414-i1-1.1_001622	754252.PFREUD_18560	2.76e-306	835.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria	201174|Actinobacteria	M	amidohydrolase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
gnl|extdb|FAM1414-i1-1.1_001623	754252.PFREUD_18550	4.58e-214	593.0	COG0586@1|root,COG0586@2|Bacteria,2IP88@201174|Actinobacteria,4DVGS@85009|Propionibacteriales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
gnl|extdb|FAM1414-i1-1.1_001624	754252.PFREUD_18540	3.07e-114	328.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4DR0K@85009|Propionibacteriales	201174|Actinobacteria	S	Appr-1'-p processing enzyme	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
gnl|extdb|FAM1414-i1-1.1_001625	754252.PFREUD_18530	3.7e-79	236.0	2AHT8@1|root,3185S@2|Bacteria,2IMSB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001626	754252.PFREUD_18520	0.0	1337.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	kch	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
gnl|extdb|FAM1414-i1-1.1_001627	754252.PFREUD_18510	0.0	1370.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DNJP@85009|Propionibacteriales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.6	-	-	MMPL
gnl|extdb|FAM1414-i1-1.1_001629	754252.PFREUD_18490	1.01e-293	801.0	COG1482@1|root,COG1482@2|Bacteria,2GJXC@201174|Actinobacteria,4DPWV@85009|Propionibacteriales	201174|Actinobacteria	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
gnl|extdb|FAM1414-i1-1.1_001630	1203605.HMPREF1531_00302	1.77e-32	115.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
gnl|extdb|FAM1414-i1-1.1_001631	754252.PFREUD_18470	0.0	1005.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNNQ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL_1	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
gnl|extdb|FAM1414-i1-1.1_001424	754252.PFREUD_20610	0.0	1756.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria,4DPDY@85009|Propionibacteriales	201174|Actinobacteria	C	Molydopterin dinucleotide binding domain	bisC	-	1.8.5.3	ko:K07306,ko:K08351	ko00780,ko00920,ko01100,map00780,map00920,map01100	-	R09501,R10127	RC02555,RC03056	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.4	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
gnl|extdb|FAM1414-i1-1.1_001432	754252.PFREUD_20530	8.64e-304	830.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4DNVR@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
gnl|extdb|FAM1414-i1-1.1_001445	754252.PFREUD_20380	1.26e-285	782.0	COG0863@1|root,COG0863@2|Bacteria,2I5QP@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001452	754252.PFREUD_20310	2.32e-123	354.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4DN6R@85009|Propionibacteriales	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
gnl|extdb|FAM1414-i1-1.1_001455	754252.PFREUD_20280	3.55e-74	223.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
gnl|extdb|FAM1414-i1-1.1_001466	754252.PFREUD_20170	2.83e-205	568.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4DP1C@85009|Propionibacteriales	201174|Actinobacteria	L	FES	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
gnl|extdb|FAM1414-i1-1.1_001471	754252.PFREUD_20120	1.85e-180	503.0	COG1266@1|root,COG1266@2|Bacteria,2GK11@201174|Actinobacteria,4DR9W@85009|Propionibacteriales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
gnl|extdb|FAM1414-i1-1.1_001480	754252.PFREUD_20030	0.0	1126.0	COG0003@1|root,COG0003@2|Bacteria	2|Bacteria	P	Pfam Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
gnl|extdb|FAM1414-i1-1.1_001508	754252.PFREUD_19720	7.62e-119	344.0	2BM8T@1|root,32FSI@2|Bacteria,2IG06@201174|Actinobacteria,4DR8K@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA adenosine	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001509	754252.PFREUD_19710	9e-98	285.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4DV8A@85009|Propionibacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
gnl|extdb|FAM1414-i1-1.1_001515	754252.PFREUD_19650	0.0	1207.0	COG0370@1|root,COG0370@2|Bacteria,2GTV2@201174|Actinobacteria	201174|Actinobacteria	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
gnl|extdb|FAM1414-i1-1.1_001522	754252.PFREUD_19580	4.91e-292	803.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4DNAN@85009|Propionibacteriales	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
gnl|extdb|FAM1414-i1-1.1_001531	754252.PFREUD_19490	0.0	1265.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPNE@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
gnl|extdb|FAM1414-i1-1.1_001533	754252.PFREUD_19470	0.0	1054.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4DPJ6@85009|Propionibacteriales	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
gnl|extdb|FAM1414-i1-1.1_001536	754252.PFREUD_19440	5.43e-159	446.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4DNJN@85009|Propionibacteriales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
gnl|extdb|FAM1414-i1-1.1_001541	754252.PFREUD_19390	8e-224	617.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria,4DNBM@85009|Propionibacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
gnl|extdb|FAM1414-i1-1.1_001545	1122175.ATXU01000002_gene1410	7.35e-278	762.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4FNGP@85023|Microbacteriaceae	201174|Actinobacteria	L	by sequence	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_001547	1122622.ATWJ01000008_gene2694	2.11e-54	176.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4FH29@85021|Intrasporangiaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
gnl|extdb|FAM1414-i1-1.1_001549	754252.PFREUD_19320	6.79e-149	421.0	COG1738@1|root,COG1738@2|Bacteria,2IFDB@201174|Actinobacteria	201174|Actinobacteria	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
gnl|extdb|FAM1414-i1-1.1_001557	754252.PFREUD_19240	0.0	1197.0	COG1297@1|root,COG1297@2|Bacteria,2I9UD@201174|Actinobacteria	201174|Actinobacteria	S	oligopeptide transporter opt family	opt	-	-	-	-	-	-	-	-	-	-	-	OPT
gnl|extdb|FAM1414-i1-1.1_001561	754252.PFREUD_19190	3.4e-159	451.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4DR1W@85009|Propionibacteriales	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
gnl|extdb|FAM1414-i1-1.1_001562	754252.PFREUD_19180	7.76e-160	447.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4DQX9@85009|Propionibacteriales	201174|Actinobacteria	I	SNARE associated Golgi protein	yqjA	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
gnl|extdb|FAM1414-i1-1.1_001563	754252.PFREUD_19170	7.96e-163	456.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4DN90@85009|Propionibacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
gnl|extdb|FAM1414-i1-1.1_001572	754252.PFREUD_19080	1.41e-218	601.0	COG3718@1|root,COG3718@2|Bacteria,2GM8S@201174|Actinobacteria,4DQKK@85009|Propionibacteriales	201174|Actinobacteria	G	KduI/IolB family	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
gnl|extdb|FAM1414-i1-1.1_001601	754252.PFREUD_18790	3.09e-252	694.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4DP15@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
gnl|extdb|FAM1414-i1-1.1_001605	754252.PFREUD_18750	9.12e-107	308.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4DQIJ@85009|Propionibacteriales	201174|Actinobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3581c	YgbB
gnl|extdb|FAM1414-i1-1.1_001608	754252.PFREUD_18720	0.0	936.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4DTIR@85009|Propionibacteriales	201174|Actinobacteria	E	COG1113 Gamma-aminobutyrate permease and related permeases	-	-	-	ko:K11738	-	-	-	-	ko00000,ko02000	2.A.3.1.8	-	-	AA_permease
gnl|extdb|FAM1414-i1-1.1_001609	754252.PFREUD_18700	0.0	910.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4DTIR@85009|Propionibacteriales	201174|Actinobacteria	E	COG1113 Gamma-aminobutyrate permease and related permeases	-	-	-	ko:K11738	-	-	-	-	ko00000,ko02000	2.A.3.1.8	-	-	AA_permease
gnl|extdb|FAM1414-i1-1.1_001694	1122998.AUHZ01000010_gene1562	4.41e-26	97.8	COG2801@1|root,COG2801@2|Bacteria,2GTHN@201174|Actinobacteria,4DWUJ@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
gnl|extdb|FAM1414-i1-1.1_001695	754252.PFREUD_16330	0.0	943.0	COG1027@1|root,COG1027@2|Bacteria,2I2HG@201174|Actinobacteria,4DPWH@85009|Propionibacteriales	201174|Actinobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
gnl|extdb|FAM1414-i1-1.1_001696	754252.PFREUD_16320	0.0	962.0	COG1027@1|root,COG1027@2|Bacteria,2I2HG@201174|Actinobacteria,4DPWH@85009|Propionibacteriales	201174|Actinobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
gnl|extdb|FAM1414-i1-1.1_001698	754252.PFREUD_16300	0.0	954.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4DNS5@85009|Propionibacteriales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
gnl|extdb|FAM1414-i1-1.1_001699	754252.PFREUD_16290	3.69e-232	639.0	COG1052@1|root,COG1052@2|Bacteria,2HBNQ@201174|Actinobacteria,4DPGQ@85009|Propionibacteriales	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
gnl|extdb|FAM1414-i1-1.1_001700	754252.PFREUD_16280	1.84e-78	232.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4DR37@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4
gnl|extdb|FAM1414-i1-1.1_001701	754252.PFREUD_16270	5.53e-266	728.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4DNQA@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
gnl|extdb|FAM1414-i1-1.1_001702	754252.PFREUD_16260	6.7e-203	561.0	COG0739@1|root,COG0739@2|Bacteria,2GKXN@201174|Actinobacteria,4DQPK@85009|Propionibacteriales	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001703	754252.PFREUD_16250	2.12e-226	623.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4DMZE@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
gnl|extdb|FAM1414-i1-1.1_001704	754252.PFREUD_16240	6.49e-269	735.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4DN9X@85009|Propionibacteriales	201174|Actinobacteria	E	Succinyl-diaminopimelate desuccinylase	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
gnl|extdb|FAM1414-i1-1.1_001705	754252.PFREUD_16230	1.4e-199	553.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4DPM7@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
gnl|extdb|FAM1414-i1-1.1_001707	1122994.AUFR01000009_gene1715	1.39e-19	85.5	2DR5U@1|root,33AAR@2|Bacteria,2GX63@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001708	754252.PFREUD_16200	2.77e-30	107.0	2E39N@1|root,32Y97@2|Bacteria,2GQFF@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3117
gnl|extdb|FAM1414-i1-1.1_001709	754252.PFREUD_16190	6.38e-300	817.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4DN2C@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl transferases group 1	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
gnl|extdb|FAM1414-i1-1.1_001710	754252.PFREUD_16180	1.32e-309	842.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4DPN8@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
gnl|extdb|FAM1414-i1-1.1_001711	754252.PFREUD_16170	1.23e-150	424.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,4DNEI@85009|Propionibacteriales	201174|Actinobacteria	S	O-methyltransferase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
gnl|extdb|FAM1414-i1-1.1_001712	754252.PFREUD_16160	1.59e-195	543.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4DNA0@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
gnl|extdb|FAM1414-i1-1.1_001713	754252.PFREUD_16150	3.11e-77	233.0	COG1826@1|root,COG1826@2|Bacteria,2IR0U@201174|Actinobacteria,4DRKC@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0008150,GO:0040007	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
gnl|extdb|FAM1414-i1-1.1_001714	754252.PFREUD_16140	2.68e-275	753.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4DNNW@85009|Propionibacteriales	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
gnl|extdb|FAM1414-i1-1.1_001715	754252.PFREUD_16130	1.23e-106	310.0	COG4420@1|root,COG4420@2|Bacteria,2GJRV@201174|Actinobacteria,4DQT8@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
gnl|extdb|FAM1414-i1-1.1_001717	754252.PFREUD_16110	7.51e-203	561.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4DPA5@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	mcl2	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI,PEP-utilizers_C
gnl|extdb|FAM1414-i1-1.1_001718	754252.PFREUD_16100	1.28e-177	498.0	2CAW2@1|root,32RS7@2|Bacteria,2IB15@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001719	754252.PFREUD_16090	0.0	977.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4DNH3@85009|Propionibacteriales	201174|Actinobacteria	E	to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
gnl|extdb|FAM1414-i1-1.1_001720	754252.PFREUD_16080	5.15e-165	462.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4DV7K@85009|Propionibacteriales	201174|Actinobacteria	S	C4-type zinc ribbon domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
gnl|extdb|FAM1414-i1-1.1_001722	754252.PFREUD_16070	2.06e-197	547.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Polysacc_deac_1,SLH,VCBS
gnl|extdb|FAM1414-i1-1.1_001724	754252.PFREUD_16050	1.24e-231	637.0	2DYIV@1|root,34A0Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510
gnl|extdb|FAM1414-i1-1.1_001725	754252.PFREUD_16040	1.32e-215	594.0	2DYIV@1|root,34A0Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510
gnl|extdb|FAM1414-i1-1.1_001726	754252.PFREUD_16030	0.0	899.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4DNNP@85009|Propionibacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
gnl|extdb|FAM1414-i1-1.1_001727	754252.PFREUD_16020	6.83e-169	472.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
gnl|extdb|FAM1414-i1-1.1_001728	754252.PFREUD_16010	0.0	1904.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4DPAV@85009|Propionibacteriales	201174|Actinobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
gnl|extdb|FAM1414-i1-1.1_001729	754252.PFREUD_16000	1.05e-185	517.0	COG1028@1|root,COG1028@2|Bacteria,2I2RJ@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase	dprE2	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	iNJ661.Rv3791	adh_short
gnl|extdb|FAM1414-i1-1.1_001730	754252.PFREUD_15990	8.5e-131	372.0	COG1309@1|root,COG1309@2|Bacteria,2HAGC@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	tetR	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
gnl|extdb|FAM1414-i1-1.1_001733	754252.PFREUD_15960	0.0	1174.0	COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4DNB0@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	yjjK	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
gnl|extdb|FAM1414-i1-1.1_001734	754252.PFREUD_15950	3.21e-152	431.0	2AUFS@1|root,31K3Y@2|Bacteria,2GIXC@201174|Actinobacteria,4DQHR@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4191)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4191
gnl|extdb|FAM1414-i1-1.1_001735	754252.PFREUD_15940	4.3e-315	870.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4DNH6@85009|Propionibacteriales	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	sucB	GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008289,GO:0009405,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0030312,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043177,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
gnl|extdb|FAM1414-i1-1.1_001736	754252.PFREUD_15930	2.86e-276	755.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4DN5V@85009|Propionibacteriales	201174|Actinobacteria	E	Glycine cleavage system T protein	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
gnl|extdb|FAM1414-i1-1.1_001737	267747.PPA0696	1.46e-07	50.8	2EFWK@1|root,339NW@2|Bacteria,2IQXQ@201174|Actinobacteria,4DSKV@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001738	767029.HMPREF9154_2090	1.52e-38	139.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4DRVQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3043)	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
gnl|extdb|FAM1414-i1-1.1_001739	754252.PFREUD_15890	1.77e-169	475.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4DPJS@85009|Propionibacteriales	201174|Actinobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
gnl|extdb|FAM1414-i1-1.1_001740	1122998.AUHZ01000004_gene1041	3.7e-21	87.0	2E7WR@1|root,332BD@2|Bacteria,2I8C0@201174|Actinobacteria,4DS76@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001741	754252.PFREUD_15870	2.06e-207	575.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
gnl|extdb|FAM1414-i1-1.1_001742	754252.PFREUD_15860	1.63e-79	236.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4DR9B@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
gnl|extdb|FAM1414-i1-1.1_001743	754252.PFREUD_15850	0.0	935.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GNDC@201174|Actinobacteria,4DN4P@85009|Propionibacteriales	201174|Actinobacteria	F	IMP dehydrogenase GMP reductase	guaB1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
gnl|extdb|FAM1414-i1-1.1_001744	754252.PFREUD_15840	1.02e-119	342.0	COG0784@1|root,COG0784@2|Bacteria,2II71@201174|Actinobacteria,4DQR3@85009|Propionibacteriales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Response_reg
gnl|extdb|FAM1414-i1-1.1_001745	754252.PFREUD_15830	2.1e-247	679.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4DP4R@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
gnl|extdb|FAM1414-i1-1.1_001747	754252.PFREUD_15810	1.69e-160	449.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	pppA	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
gnl|extdb|FAM1414-i1-1.1_001749	754252.PFREUD_15790	5e-279	761.0	COG1670@1|root,COG4696@1|root,COG1670@2|Bacteria,COG4696@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	XK27_03185	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Acetyltransf_3,Hydrolase_3,PRA-PH
gnl|extdb|FAM1414-i1-1.1_001750	754252.PFREUD_15780	5.4e-201	561.0	COG0088@1|root,COG0088@2|Bacteria,2GXD5@201174|Actinobacteria,4DVXM@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	-	-	-	-	-	-	-	-	-	-	-	-	DUF5324
gnl|extdb|FAM1414-i1-1.1_001751	754252.PFREUD_15770	1.16e-123	352.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4DQA4@85009|Propionibacteriales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
gnl|extdb|FAM1414-i1-1.1_001752	754252.PFREUD_15760	3.97e-54	169.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4DRN1@85009|Propionibacteriales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
gnl|extdb|FAM1414-i1-1.1_001753	754252.PFREUD_15750	1.11e-245	677.0	COG4942@1|root,COG4942@2|Bacteria,2GP1Y@201174|Actinobacteria,4DWGE@85009|Propionibacteriales	201174|Actinobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
gnl|extdb|FAM1414-i1-1.1_001754	754252.PFREUD_15740	9.51e-203	561.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4DP1S@85009|Propionibacteriales	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
gnl|extdb|FAM1414-i1-1.1_001755	754252.PFREUD_15730	1.94e-221	611.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,Cytidylate_kin
gnl|extdb|FAM1414-i1-1.1_001757	754252.PFREUD_15710	8.79e-163	454.0	COG2220@1|root,COG2220@2|Bacteria,2GNHK@201174|Actinobacteria,4DQBG@85009|Propionibacteriales	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
gnl|extdb|FAM1414-i1-1.1_001758	754252.PFREUD_15700	8.66e-203	563.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4DPV8@85009|Propionibacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
gnl|extdb|FAM1414-i1-1.1_001759	754252.PFREUD_15690	0.0	1395.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DPC3@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
gnl|extdb|FAM1414-i1-1.1_001763	1122138.AQUZ01000033_gene3548	2e-06	51.2	2ERD0@1|root,33IYN@2|Bacteria,2GXC0@201174|Actinobacteria,4DSVZ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001764	754252.PFREUD_15640	0.0	2342.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
gnl|extdb|FAM1414-i1-1.1_001766	754252.PFREUD_15610	1.7e-84	249.0	2E49S@1|root,32Z5G@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
gnl|extdb|FAM1414-i1-1.1_001767	754252.PFREUD_15590	1.27e-99	289.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4DQJP@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
gnl|extdb|FAM1414-i1-1.1_001769	754252.PFREUD_15570	4.09e-100	292.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	ftsL	-	-	ko:K05589,ko:K12065	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
gnl|extdb|FAM1414-i1-1.1_001772	754252.PFREUD_15540	0.0	956.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4DNW8@85009|Propionibacteriales	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
gnl|extdb|FAM1414-i1-1.1_001773	754252.PFREUD_15530	7.44e-257	704.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4DNZ9@85009|Propionibacteriales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
gnl|extdb|FAM1414-i1-1.1_001774	754252.PFREUD_15520	0.0	971.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4DNTV@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
gnl|extdb|FAM1414-i1-1.1_001775	754252.PFREUD_15510	1.88e-291	797.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
gnl|extdb|FAM1414-i1-1.1_001777	754252.PFREUD_15490	0.0	945.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4DNNN@85009|Propionibacteriales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
gnl|extdb|FAM1414-i1-1.1_001778	754252.PFREUD_15480	1.61e-166	466.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	6.3.2.4	ko:K01921,ko:K03589,ko:K06438	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
gnl|extdb|FAM1414-i1-1.1_001779	754252.PFREUD_15470	1.15e-281	771.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4DND0@85009|Propionibacteriales	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
gnl|extdb|FAM1414-i1-1.1_001780	754252.PFREUD_15460	9.44e-189	524.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4DR2J@85009|Propionibacteriales	201174|Actinobacteria	S	Multi-copper polyphenol oxidoreductase laccase	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
gnl|extdb|FAM1414-i1-1.1_001781	754252.PFREUD_15450	1.51e-116	334.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4DR13@85009|Propionibacteriales	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
gnl|extdb|FAM1414-i1-1.1_001783	754252.PFREUD_15430	6.65e-126	370.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
gnl|extdb|FAM1414-i1-1.1_001784	754252.PFREUD_15420	6.34e-94	274.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4DR4Q@85009|Propionibacteriales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
gnl|extdb|FAM1414-i1-1.1_001786	754252.PFREUD_15400	1.87e-217	600.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4DN88@85009|Propionibacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
gnl|extdb|FAM1414-i1-1.1_001787	754252.PFREUD_15390	0.0	978.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4DPR2@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
gnl|extdb|FAM1414-i1-1.1_001789	754252.PFREUD_15370	1.5e-135	385.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
gnl|extdb|FAM1414-i1-1.1_001790	754252.PFREUD_15360	0.0	1749.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4DNJG@85009|Propionibacteriales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
gnl|extdb|FAM1414-i1-1.1_001791	754252.PFREUD_15350	1.18e-95	282.0	2DXBZ@1|root,344BK@2|Bacteria,2I77B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
gnl|extdb|FAM1414-i1-1.1_001792	754252.PFREUD_15340	0.0	954.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DNDH@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
gnl|extdb|FAM1414-i1-1.1_001793	754252.PFREUD_15330	1.6e-308	845.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4DPIM@85009|Propionibacteriales	201174|Actinobacteria	J	ribosomal protein	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
gnl|extdb|FAM1414-i1-1.1_001794	754252.PFREUD_15320	9.83e-189	523.0	COG2820@1|root,COG2820@2|Bacteria,2IT3V@201174|Actinobacteria	201174|Actinobacteria	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
gnl|extdb|FAM1414-i1-1.1_001795	754252.PFREUD_15310	1.39e-152	429.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4DQNK@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
gnl|extdb|FAM1414-i1-1.1_001796	754252.PFREUD_15300	0.0	1359.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4DN5W@85009|Propionibacteriales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
gnl|extdb|FAM1414-i1-1.1_001797	754252.PFREUD_15290	2.38e-230	636.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4DNU5@85009|Propionibacteriales	201174|Actinobacteria	P	Membrane protein TerC	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
gnl|extdb|FAM1414-i1-1.1_001798	754252.PFREUD_15280	2.45e-145	409.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,4DPUP@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
gnl|extdb|FAM1414-i1-1.1_001799	754252.PFREUD_15270	1.63e-182	507.0	2C7TJ@1|root,31RF6@2|Bacteria,2GP9X@201174|Actinobacteria,4DS45@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	5.2.1.4	ko:K16163	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	MDMPI_C,MDMPI_N
gnl|extdb|FAM1414-i1-1.1_001800	754252.PFREUD_15260	0.0	2014.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DN4J@85009|Propionibacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001801	754252.PFREUD_15250	1.98e-128	364.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Acetyltransf_3
gnl|extdb|FAM1414-i1-1.1_001802	754252.PFREUD_15240	2.62e-263	723.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4DQIN@85009|Propionibacteriales	201174|Actinobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
gnl|extdb|FAM1414-i1-1.1_001803	754252.PFREUD_15230	3.19e-207	573.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4DP66@85009|Propionibacteriales	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
gnl|extdb|FAM1414-i1-1.1_001804	754252.PFREUD_15220	1.48e-140	398.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DTUQ@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
gnl|extdb|FAM1414-i1-1.1_001805	754252.PFREUD_15210	4.36e-305	834.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4DRHK@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
gnl|extdb|FAM1414-i1-1.1_001806	754252.PFREUD_15200	0.0	1297.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4DN4X@85009|Propionibacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
gnl|extdb|FAM1414-i1-1.1_001807	754252.PFREUD_15190	7.57e-211	582.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4DPVQ@85009|Propionibacteriales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
gnl|extdb|FAM1414-i1-1.1_001808	754252.PFREUD_15180	5.17e-223	615.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4DNYU@85009|Propionibacteriales	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
gnl|extdb|FAM1414-i1-1.1_001809	754252.PFREUD_15170	4.76e-219	607.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4DNGS@85009|Propionibacteriales	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
gnl|extdb|FAM1414-i1-1.1_001810	266940.Krad_3778	3.81e-93	281.0	COG1136@1|root,COG1136@2|Bacteria,2GM25@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001811	754252.PFREUD_15140	8.99e-88	272.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
gnl|extdb|FAM1414-i1-1.1_001812	754252.PFREUD_15130	4.53e-239	657.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4DNQ8@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
gnl|extdb|FAM1414-i1-1.1_001813	754252.PFREUD_15120	1.85e-282	773.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4DNJD@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
gnl|extdb|FAM1414-i1-1.1_001814	754252.PFREUD_15110	2.39e-182	508.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4DP7B@85009|Propionibacteriales	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
gnl|extdb|FAM1414-i1-1.1_001816	754252.PFREUD_15090	5.65e-81	239.0	2CNY9@1|root,31GEE@2|Bacteria,2IKKZ@201174|Actinobacteria	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	-	-	-	-	-	-	-	-	-	-	-	RbpA
gnl|extdb|FAM1414-i1-1.1_001817	754252.PFREUD_15080	3.99e-178	496.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4DQAQ@85009|Propionibacteriales	201174|Actinobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
gnl|extdb|FAM1414-i1-1.1_001818	754252.PFREUD_15070	4.03e-209	578.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4DP29@85009|Propionibacteriales	201174|Actinobacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
gnl|extdb|FAM1414-i1-1.1_001820	754252.PFREUD_15050	0.0	926.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4DPW7@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	pdxR	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
gnl|extdb|FAM1414-i1-1.1_001821	754252.PFREUD_15040	5.26e-203	563.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4DNEB@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
gnl|extdb|FAM1414-i1-1.1_001822	754252.PFREUD_15030	7.39e-131	373.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
gnl|extdb|FAM1414-i1-1.1_001823	525246.HMPREF0058_2332	1.44e-17	87.4	2DJRM@1|root,3072U@2|Bacteria,2IIWH@201174|Actinobacteria,4D7YY@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001824	754252.PFREUD_15010	1.98e-166	465.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001825	754252.PFREUD_15000	1.12e-83	247.0	COG1725@1|root,COG1725@2|Bacteria,2IKDF@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
gnl|extdb|FAM1414-i1-1.1_001827	754252.PFREUD_14980	0.0	976.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4DN7B@85009|Propionibacteriales	201174|Actinobacteria	O	Uncharacterized protein family (UPF0051)	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
gnl|extdb|FAM1414-i1-1.1_001828	754252.PFREUD_14970	6.56e-293	799.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria	201174|Actinobacteria	O	FeS assembly protein SufD	sufD	GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
gnl|extdb|FAM1414-i1-1.1_001829	754252.PFREUD_14960	2.24e-81	240.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
gnl|extdb|FAM1414-i1-1.1_001830	754252.PFREUD_14950	3.99e-179	498.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4DNC0@85009|Propionibacteriales	201174|Actinobacteria	O	assembly ATPase	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001831	754252.PFREUD_14940	6.01e-307	836.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4DNCW@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
gnl|extdb|FAM1414-i1-1.1_001832	754252.PFREUD_14930	5.98e-105	303.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4DQS7@85009|Propionibacteriales	201174|Actinobacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
gnl|extdb|FAM1414-i1-1.1_001834	754252.PFREUD_14910	0.0	1010.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4DPPB@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
gnl|extdb|FAM1414-i1-1.1_001835	754252.PFREUD_14890	1.58e-199	552.0	COG0500@1|root,COG2226@2|Bacteria,2HCAN@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
gnl|extdb|FAM1414-i1-1.1_001836	754252.PFREUD_14880	1.31e-163	459.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4DNZG@85009|Propionibacteriales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
gnl|extdb|FAM1414-i1-1.1_001838	754252.PFREUD_14860	3.82e-181	504.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4DNM7@85009|Propionibacteriales	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
gnl|extdb|FAM1414-i1-1.1_001839	1121933.AUHH01000032_gene1975	1.78e-45	159.0	2BK9Y@1|root,32EQ4@2|Bacteria,2GMZH@201174|Actinobacteria,4DR19@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001840	754252.PFREUD_14840	1.29e-187	521.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4DNDT@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001842	754252.PFREUD_14820	1.24e-192	534.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4DN3T@85009|Propionibacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
gnl|extdb|FAM1414-i1-1.1_001843	754252.PFREUD_14810	2.34e-152	427.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4DQAV@85009|Propionibacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
gnl|extdb|FAM1414-i1-1.1_001844	754252.PFREUD_14800	2.28e-219	605.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DN7T@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
gnl|extdb|FAM1414-i1-1.1_001845	754252.PFREUD_14790	1.52e-265	729.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
gnl|extdb|FAM1414-i1-1.1_001846	754252.PFREUD_14780	9.29e-207	575.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4DP30@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
gnl|extdb|FAM1414-i1-1.1_001847	754252.PFREUD_14770	1.42e-178	499.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4DNDW@85009|Propionibacteriales	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
gnl|extdb|FAM1414-i1-1.1_001848	754252.PFREUD_14760	5.47e-167	467.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4DNEC@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
gnl|extdb|FAM1414-i1-1.1_001849	754252.PFREUD_14750	2.46e-121	347.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4DNKY@85009|Propionibacteriales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
gnl|extdb|FAM1414-i1-1.1_001850	754252.PFREUD_14740	6.42e-201	556.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4DQ6M@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
gnl|extdb|FAM1414-i1-1.1_001852	754252.PFREUD_14720	2.82e-280	766.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4DND1@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
gnl|extdb|FAM1414-i1-1.1_001854	754252.PFREUD_14700	1.53e-202	560.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4DP1G@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
gnl|extdb|FAM1414-i1-1.1_001855	754252.PFREUD_14690	0.0	1160.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4DN8W@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
gnl|extdb|FAM1414-i1-1.1_001857	754252.PFREUD_14670	7.43e-107	308.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,4DRA1@85009|Propionibacteriales	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
gnl|extdb|FAM1414-i1-1.1_001858	754252.PFREUD_14660	7.94e-249	683.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4DN47@85009|Propionibacteriales	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
gnl|extdb|FAM1414-i1-1.1_001860	754252.PFREUD_14640	0.0	1638.0	COG0481@1|root,COG0532@1|root,COG0481@2|Bacteria,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4DN57@85009|Propionibacteriales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
gnl|extdb|FAM1414-i1-1.1_001861	754252.PFREUD_14630	2.98e-94	275.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4DR3E@85009|Propionibacteriales	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
gnl|extdb|FAM1414-i1-1.1_001862	754252.PFREUD_14620	1.41e-208	577.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4DPKY@85009|Propionibacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
gnl|extdb|FAM1414-i1-1.1_001863	754252.PFREUD_14610	5.49e-193	535.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4DPG7@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
gnl|extdb|FAM1414-i1-1.1_001864	754252.PFREUD_14600	0.0	1001.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4DNYQ@85009|Propionibacteriales	201174|Actinobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
gnl|extdb|FAM1414-i1-1.1_001865	754252.PFREUD_14590	7.52e-238	653.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4DNXK@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
gnl|extdb|FAM1414-i1-1.1_001866	754252.PFREUD_14580	1.02e-55	173.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4DS16@85009|Propionibacteriales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
gnl|extdb|FAM1414-i1-1.1_001867	754252.PFREUD_14570	0.0	1421.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4DP91@85009|Propionibacteriales	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
gnl|extdb|FAM1414-i1-1.1_001868	754252.PFREUD_14560	2.3e-172	481.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4DNG2@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
gnl|extdb|FAM1414-i1-1.1_001869	1032480.MLP_15900	4.92e-14	77.0	2AQTN@1|root,31G1R@2|Bacteria,2IACN@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2993
gnl|extdb|FAM1414-i1-1.1_001870	754252.PFREUD_14540	4.5e-124	353.0	COG0454@1|root,COG0456@2|Bacteria,2I2XB@201174|Actinobacteria,4DQWV@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
gnl|extdb|FAM1414-i1-1.1_001871	754252.PFREUD_14530	0.0	1108.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4DMZI@85009|Propionibacteriales	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
gnl|extdb|FAM1414-i1-1.1_001872	754252.PFREUD_14520	5.14e-42	137.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
gnl|extdb|FAM1414-i1-1.1_001874	754252.PFREUD_14500	3.04e-100	290.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4DVJV@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
gnl|extdb|FAM1414-i1-1.1_001875	754252.PFREUD_14490	8.49e-138	390.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4DQZ1@85009|Propionibacteriales	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
gnl|extdb|FAM1414-i1-1.1_001876	754252.PFREUD_14480	3.12e-110	317.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4DR12@85009|Propionibacteriales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
gnl|extdb|FAM1414-i1-1.1_001877	754252.PFREUD_14470	4.45e-138	389.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4DQUU@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
gnl|extdb|FAM1414-i1-1.1_001878	1111131.HMPREF1255_0135	3.06e-28	102.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4DS4H@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
gnl|extdb|FAM1414-i1-1.1_001879	754252.PFREUD_14460	7.16e-173	482.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4DN7J@85009|Propionibacteriales	201174|Actinobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
gnl|extdb|FAM1414-i1-1.1_001880	754252.PFREUD_14440	4.42e-218	601.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4DN5R@85009|Propionibacteriales	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
gnl|extdb|FAM1414-i1-1.1_001881	754252.PFREUD_14430	8.75e-138	390.0	COG2246@1|root,COG2246@2|Bacteria,2IQYV@201174|Actinobacteria	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
gnl|extdb|FAM1414-i1-1.1_001882	754252.PFREUD_14420	0.0	1953.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DN2T@85009|Propionibacteriales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
gnl|extdb|FAM1414-i1-1.1_001884	754252.PFREUD_14400	1.53e-237	657.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4DN3Z@85009|Propionibacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
gnl|extdb|FAM1414-i1-1.1_001885	754252.PFREUD_14390	0.0	949.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4DNUI@85009|Propionibacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
gnl|extdb|FAM1414-i1-1.1_001886	754252.PFREUD_14380	2.36e-270	739.0	COG1228@1|root,COG1228@2|Bacteria,2GKRZ@201174|Actinobacteria,4DP0W@85009|Propionibacteriales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
gnl|extdb|FAM1414-i1-1.1_001887	754252.PFREUD_14370	3.35e-106	307.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4DQZU@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
gnl|extdb|FAM1414-i1-1.1_001888	754252.PFREUD_14360	1.6e-53	167.0	COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4DSI2@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the UPF0109 family	-	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
gnl|extdb|FAM1414-i1-1.1_001889	754252.PFREUD_14350	8.96e-123	350.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4DRAZ@85009|Propionibacteriales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
gnl|extdb|FAM1414-i1-1.1_001891	754252.PFREUD_14330	6.4e-172	479.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DLH,Peptidase_S9
gnl|extdb|FAM1414-i1-1.1_001892	754252.PFREUD_14320	4.13e-168	471.0	28HIR@1|root,2Z7U4@2|Bacteria,2GN2S@201174|Actinobacteria,4DQJ4@85009|Propionibacteriales	201174|Actinobacteria	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
gnl|extdb|FAM1414-i1-1.1_001893	754252.PFREUD_14310	0.0	1377.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DN0E@85009|Propionibacteriales	201174|Actinobacteria	C	succinate dehydrogenase	sdhA	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
gnl|extdb|FAM1414-i1-1.1_001894	754252.PFREUD_14300	1.02e-188	523.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4DPU6@85009|Propionibacteriales	201174|Actinobacteria	C	Succinate dehydrogenase fumarate reductase	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
gnl|extdb|FAM1414-i1-1.1_001895	754252.PFREUD_14290	4.31e-76	227.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4DQSW@85009|Propionibacteriales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
gnl|extdb|FAM1414-i1-1.1_001896	754252.PFREUD_14280	1.34e-177	494.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4DQK9@85009|Propionibacteriales	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
gnl|extdb|FAM1414-i1-1.1_001898	754252.PFREUD_14260	7.91e-70	210.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4DR0E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
gnl|extdb|FAM1414-i1-1.1_001899	754252.PFREUD_14250	4.98e-85	250.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
gnl|extdb|FAM1414-i1-1.1_001900	754252.PFREUD_14240	0.0	986.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4DNC3@85009|Propionibacteriales	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
gnl|extdb|FAM1414-i1-1.1_001901	754252.PFREUD_14230	2.13e-277	758.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria	201174|Actinobacteria	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
gnl|extdb|FAM1414-i1-1.1_001902	754252.PFREUD_14220	0.0	907.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4DPK3@85009|Propionibacteriales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
gnl|extdb|FAM1414-i1-1.1_001903	754252.PFREUD_14210	1.14e-87	257.0	COG1433@1|root,COG1433@2|Bacteria,2GSU0@201174|Actinobacteria,4DVMP@85009|Propionibacteriales	201174|Actinobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
gnl|extdb|FAM1414-i1-1.1_001904	754252.PFREUD_14200	3.25e-188	524.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4DQ00@85009|Propionibacteriales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
gnl|extdb|FAM1414-i1-1.1_001907	1410634.JHVD01000001_gene1407	0.000207	44.3	COG2856@1|root,COG2856@2|Bacteria,2GWUV@201174|Actinobacteria,4DVWS@85009|Propionibacteriales	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001911	754252.PFREUD_14130	1.19e-315	858.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,4DNNY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
gnl|extdb|FAM1414-i1-1.1_001912	754252.PFREUD_14120	0.0	1384.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4DWPQ@85009|Propionibacteriales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
gnl|extdb|FAM1414-i1-1.1_001913	754252.PFREUD_14110	5.44e-56	174.0	COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria	201174|Actinobacteria	E	Phosphoribosyl-ATP	hisE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
gnl|extdb|FAM1414-i1-1.1_001914	754252.PFREUD_14100	2.81e-198	550.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4DTZ7@85009|Propionibacteriales	201174|Actinobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
gnl|extdb|FAM1414-i1-1.1_001915	1032480.MLP_17080	1.5e-08	58.5	2F46V@1|root,33WXW@2|Bacteria,2II56@201174|Actinobacteria,4DS70@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001916	754252.PFREUD_14070	2.07e-150	425.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4DNG8@85009|Propionibacteriales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
gnl|extdb|FAM1414-i1-1.1_001917	754252.PFREUD_14060	1.19e-37	126.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4DSHV@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
gnl|extdb|FAM1414-i1-1.1_001918	754252.PFREUD_14050	1.86e-77	231.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4DQY2@85009|Propionibacteriales	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
gnl|extdb|FAM1414-i1-1.1_001919	754252.PFREUD_14040	1.71e-203	563.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
gnl|extdb|FAM1414-i1-1.1_001921	754252.PFREUD_14020	2.09e-266	729.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4DPA8@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
gnl|extdb|FAM1414-i1-1.1_001922	754252.PFREUD_14010	0.0	1662.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,4DPEJ@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
gnl|extdb|FAM1414-i1-1.1_001923	754252.PFREUD_14000	3.87e-305	830.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4DN56@85009|Propionibacteriales	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	iNJ661.Rv0337c	Aminotran_1_2
gnl|extdb|FAM1414-i1-1.1_001924	754252.PFREUD_13990	7.94e-249	682.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4DNZ7@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
gnl|extdb|FAM1414-i1-1.1_001925	754252.PFREUD_13980	2.2e-273	748.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4DN1T@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
gnl|extdb|FAM1414-i1-1.1_001926	754252.PFREUD_13970	5.54e-213	588.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4DPCE@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
gnl|extdb|FAM1414-i1-1.1_001927	754252.PFREUD_13960	9.23e-298	812.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4DNMX@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class-III	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
gnl|extdb|FAM1414-i1-1.1_001928	754252.PFREUD_13950	2.55e-118	339.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4DQUP@85009|Propionibacteriales	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
gnl|extdb|FAM1414-i1-1.1_001929	754252.PFREUD_13940	0.0	892.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4DPEP@85009|Propionibacteriales	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
gnl|extdb|FAM1414-i1-1.1_001930	754252.PFREUD_13930	5.09e-301	821.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4DNWH@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
gnl|extdb|FAM1414-i1-1.1_001706	754252.PFREUD_16220	2.78e-311	850.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria	201174|Actinobacteria	P	Chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
gnl|extdb|FAM1414-i1-1.1_001716	754252.PFREUD_16120	1.47e-252	699.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,4DPA3@85009|Propionibacteriales	201174|Actinobacteria	P	MgtE intracellular N domain	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
gnl|extdb|FAM1414-i1-1.1_001723	754252.PFREUD_16060	5.9e-205	567.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria,4DN75@85009|Propionibacteriales	201174|Actinobacteria	J	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
gnl|extdb|FAM1414-i1-1.1_001732	754252.PFREUD_15970	0.0	988.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4DNAS@85009|Propionibacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
gnl|extdb|FAM1414-i1-1.1_001756	754252.PFREUD_15720	0.0	904.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4DNES@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	aroG	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.5.1.54	ko:K01626,ko:K16019	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01051,map01100,map01110,map01130,map01230,map02024	M00022	R01826,R06591	RC00435,RC01556	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2178c	DAHP_synth_2
gnl|extdb|FAM1414-i1-1.1_001760	754252.PFREUD_15680	2.2e-253	695.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4DNU8@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
gnl|extdb|FAM1414-i1-1.1_001761	754252.PFREUD_15670	5.65e-229	630.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4DPM1@85009|Propionibacteriales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
gnl|extdb|FAM1414-i1-1.1_001762	754252.PFREUD_15660	0.0	1365.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DPXT@85009|Propionibacteriales	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2
gnl|extdb|FAM1414-i1-1.1_001765	754252.PFREUD_15620	3.95e-292	798.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DP99@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
gnl|extdb|FAM1414-i1-1.1_001768	754252.PFREUD_15580	7.1e-222	613.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4DPXU@85009|Propionibacteriales	201174|Actinobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
gnl|extdb|FAM1414-i1-1.1_001770	754252.PFREUD_15560	0.0	1175.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4DNVU@85009|Propionibacteriales	201174|Actinobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
gnl|extdb|FAM1414-i1-1.1_001771	754252.PFREUD_15550	0.0	1037.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4DN64@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
gnl|extdb|FAM1414-i1-1.1_001776	754252.PFREUD_15500	4.64e-255	700.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4DN0T@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
gnl|extdb|FAM1414-i1-1.1_001782	754252.PFREUD_15440	1.33e-42	140.0	COG0762@1|root,COG0762@2|Bacteria	2|Bacteria	D	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
gnl|extdb|FAM1414-i1-1.1_001785	754252.PFREUD_15410	9.36e-124	353.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
gnl|extdb|FAM1414-i1-1.1_001815	754252.PFREUD_15100	9.54e-47	150.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4DS3V@85009|Propionibacteriales	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
gnl|extdb|FAM1414-i1-1.1_001819	754252.PFREUD_15060	0.0	1048.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4DNXH@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
gnl|extdb|FAM1414-i1-1.1_001826	754252.PFREUD_14990	4.31e-181	504.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,4DQCB@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
gnl|extdb|FAM1414-i1-1.1_001833	754252.PFREUD_14920	1.03e-93	274.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4DR2I@85009|Propionibacteriales	201174|Actinobacteria	S	Pfam:DUF59	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
gnl|extdb|FAM1414-i1-1.1_001837	754252.PFREUD_14870	1.38e-155	438.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,4DPI8@85009|Propionibacteriales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
gnl|extdb|FAM1414-i1-1.1_001841	754252.PFREUD_14830	6.63e-219	606.0	COG0385@1|root,COG0385@2|Bacteria,2GJQU@201174|Actinobacteria,4DT11@85009|Propionibacteriales	201174|Actinobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
gnl|extdb|FAM1414-i1-1.1_001851	754252.PFREUD_14730	9.95e-275	750.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4DPW3@85009|Propionibacteriales	201174|Actinobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
gnl|extdb|FAM1414-i1-1.1_001853	754252.PFREUD_14710	4.92e-269	737.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4DP7G@85009|Propionibacteriales	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
gnl|extdb|FAM1414-i1-1.1_001859	1171373.PACID_21840	1.14e-17	77.0	COG2740@1|root,COG2740@2|Bacteria	2|Bacteria	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
gnl|extdb|FAM1414-i1-1.1_001873	754252.PFREUD_14510	0.0	1377.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4DNNB@85009|Propionibacteriales	201174|Actinobacteria	L	ATP-dependent DNA helicase RecG	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
gnl|extdb|FAM1414-i1-1.1_001890	754252.PFREUD_14340	3.37e-177	494.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4DNVI@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
gnl|extdb|FAM1414-i1-1.1_001897	754252.PFREUD_14270	4.26e-142	401.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4DPWD@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
gnl|extdb|FAM1414-i1-1.1_001910	754252.PFREUD_14140	6.19e-239	656.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DPF5@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
gnl|extdb|FAM1414-i1-1.1_001909	754252.PFREUD_14150	8.34e-51	160.0	2EGVE@1|root,33AMN@2|Bacteria,2HZGF@201174|Actinobacteria,4DSPT@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001942	754252.PFREUD_02520	0.0	1165.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4DP3W@85009|Propionibacteriales	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
gnl|extdb|FAM1414-i1-1.1_001943	754252.PFREUD_02510	1.31e-67	204.0	COG2440@1|root,COG2440@2|Bacteria,2IREY@201174|Actinobacteria	201174|Actinobacteria	C	Psort location Cytoplasmic, score	-	-	-	ko:K03855	-	-	-	-	ko00000	-	-	-	ETF_QO
gnl|extdb|FAM1414-i1-1.1_001944	754252.PFREUD_02500	3.4e-312	850.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	fixC	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3
gnl|extdb|FAM1414-i1-1.1_001945	754252.PFREUD_02490	1.09e-192	536.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
gnl|extdb|FAM1414-i1-1.1_001946	754252.PFREUD_02480	9.95e-165	462.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
gnl|extdb|FAM1414-i1-1.1_001947	754252.PFREUD_02470	2.51e-151	425.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria	201174|Actinobacteria	S	Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
gnl|extdb|FAM1414-i1-1.1_001948	754252.PFREUD_02460	0.0	868.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08368	-	-	-	-	ko00000,ko02000	2.A.1	-	-	Sugar_tr
gnl|extdb|FAM1414-i1-1.1_001949	754252.PFREUD_02450	1.05e-225	620.0	COG2030@1|root,COG2030@2|Bacteria,2GJJI@201174|Actinobacteria,4DP3A@85009|Propionibacteriales	201174|Actinobacteria	I	MaoC like domain	hsd4B	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
gnl|extdb|FAM1414-i1-1.1_001950	754252.PFREUD_02440	0.0	1068.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	caiC	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
gnl|extdb|FAM1414-i1-1.1_001951	754252.PFREUD_02430	2.63e-305	831.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.21	ko:K07749,ko:K08298	-	-	R10643,R10644	RC00014,RC00131	ko00000,ko01000	-	-	-	CoA_transf_3
gnl|extdb|FAM1414-i1-1.1_001952	754252.PFREUD_02420	2.61e-283	773.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DT02@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	caiA	-	1.3.8.13	ko:K08297,ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
gnl|extdb|FAM1414-i1-1.1_001953	1227261.HMPREF0043_01394	1.09e-134	393.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4D4ZQ@85005|Actinomycetales	201174|Actinobacteria	I	alpha/beta hydrolase fold	lipN	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
gnl|extdb|FAM1414-i1-1.1_001954	1120945.ATUW01000001_gene1649	1.91e-180	518.0	COG2271@1|root,COG2271@2|Bacteria,2HJ93@201174|Actinobacteria,4D4W3@85005|Actinomycetales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_001955	754252.PFREUD_02320	3.43e-223	622.0	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,4DQN3@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like peptidase domain	pepA	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
gnl|extdb|FAM1414-i1-1.1_001956	754252.PFREUD_02310	8.91e-297	815.0	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,4DQN3@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like peptidase domain	pepA	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
gnl|extdb|FAM1414-i1-1.1_001958	754252.PFREUD_02290	0.0	2303.0	28HY3@1|root,2Z83I@2|Bacteria,2H218@201174|Actinobacteria	201174|Actinobacteria	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001960	754252.PFREUD_02260	8.81e-205	566.0	COG0656@1|root,COG0656@2|Bacteria,2I5YH@201174|Actinobacteria	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
gnl|extdb|FAM1414-i1-1.1_001961	754252.PFREUD_02250	6.68e-156	437.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4DNQV@85009|Propionibacteriales	201174|Actinobacteria	EH	Peptidase C26	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
gnl|extdb|FAM1414-i1-1.1_001962	754252.PFREUD_02240	6.78e-164	459.0	COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4DRBX@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
gnl|extdb|FAM1414-i1-1.1_001963	754252.PFREUD_02230	2.05e-52	166.0	2E4NY@1|root,31XN3@2|Bacteria,2GX73@201174|Actinobacteria,4DSQV@85009|Propionibacteriales	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
gnl|extdb|FAM1414-i1-1.1_001964	754252.PFREUD_02220	2.58e-228	630.0	COG0648@1|root,COG0648@2|Bacteria,2I8IU@201174|Actinobacteria	201174|Actinobacteria	L	Domain of unknown function (DUF4862)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4862
gnl|extdb|FAM1414-i1-1.1_001965	754252.PFREUD_02210	4.68e-285	783.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4DPHS@85009|Propionibacteriales	201174|Actinobacteria	C	e3 binding domain	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
gnl|extdb|FAM1414-i1-1.1_001966	754252.PFREUD_02200	2.16e-241	662.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DNN8@85009|Propionibacteriales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
gnl|extdb|FAM1414-i1-1.1_001967	754252.PFREUD_02190	1.95e-274	749.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4DNN1@85009|Propionibacteriales	201174|Actinobacteria	C	dehydrogenase, E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
gnl|extdb|FAM1414-i1-1.1_001968	754252.PFREUD_02180	5.25e-175	487.0	COG2227@1|root,COG2227@2|Bacteria,2H9ND@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
gnl|extdb|FAM1414-i1-1.1_001970	754252.PFREUD_02160	0.0	1034.0	COG0488@1|root,COG0488@2|Bacteria,2GJHN@201174|Actinobacteria,4DPS7@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001971	861299.J421_1598	1.96e-116	350.0	COG0192@1|root,COG0192@2|Bacteria,1ZSZ9@142182|Gemmatimonadetes	2|Bacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.metX	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
gnl|extdb|FAM1414-i1-1.1_001972	103733.JNYO01000007_gene5122	1.53e-40	156.0	COG0026@1|root,COG0026@2|Bacteria,2I481@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
gnl|extdb|FAM1414-i1-1.1_001973	40571.JOEA01000008_gene2661	9.59e-19	97.4	COG3146@1|root,COG3146@2|Bacteria,2IK34@201174|Actinobacteria,4E6VJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	Acetyltransf_6,FemAB_like
gnl|extdb|FAM1414-i1-1.1_001974	1123288.SOV_1c10280	5.1e-43	169.0	COG1032@1|root,COG1032@2|Bacteria,1TQJT@1239|Firmicutes,4H23J@909932|Negativicutes	909932|Negativicutes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
gnl|extdb|FAM1414-i1-1.1_001975	1120949.KB903305_gene7054	5.99e-55	185.0	COG0842@1|root,COG0842@2|Bacteria,2I8FD@201174|Actinobacteria,4DCAY@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
gnl|extdb|FAM1414-i1-1.1_001976	1157635.KB892005_gene4409	4.86e-45	158.0	COG0842@1|root,COG0842@2|Bacteria,2HDDD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
gnl|extdb|FAM1414-i1-1.1_001977	1122138.AQUZ01000039_gene8021	1.35e-133	389.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4DNSV@85009|Propionibacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001978	754252.PFREUD_02150	3.07e-139	399.0	COG0030@1|root,COG0030@2|Bacteria,2I2II@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
gnl|extdb|FAM1414-i1-1.1_001979	754252.PFREUD_02140	2.17e-76	228.0	COG1917@1|root,COG1917@2|Bacteria,2IR2V@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2
gnl|extdb|FAM1414-i1-1.1_001981	754252.PFREUD_02120	3.08e-211	583.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4DNDN@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
gnl|extdb|FAM1414-i1-1.1_001982	754252.PFREUD_02110	4.12e-158	444.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_001983	754252.PFREUD_02100	0.0	1062.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DNTU@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_001984	754252.PFREUD_02090	0.0	1296.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DN2U@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_001985	754252.PFREUD_01930	3.16e-231	636.0	2D089@1|root,32T81@2|Bacteria,2IHKJ@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
gnl|extdb|FAM1414-i1-1.1_001986	754252.PFREUD_01920	2.61e-140	397.0	COG5340@1|root,COG5340@2|Bacteria,2IM3H@201174|Actinobacteria,4DWAS@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
gnl|extdb|FAM1414-i1-1.1_001991	754252.PFREUD_01860	0.0	928.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DNGV@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
gnl|extdb|FAM1414-i1-1.1_001994	754252.PFREUD_01830	0.0	1071.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4DU0U@85009|Propionibacteriales	201174|Actinobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	preT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
gnl|extdb|FAM1414-i1-1.1_001995	754252.PFREUD_01810	2.97e-70	211.0	COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,4DR5J@85009|Propionibacteriales	201174|Actinobacteria	S	Thiamine-binding protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
gnl|extdb|FAM1414-i1-1.1_001996	754252.PFREUD_01800	1.25e-99	292.0	COG1309@1|root,COG1309@2|Bacteria,2GRWW@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_001997	754252.PFREUD_01780	0.0	926.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4DPB8@85009|Propionibacteriales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K18926	-	M00715	-	-	ko00000,ko00002,ko02000	2.A.1.3.30	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_001998	754252.PFREUD_01750	1.95e-230	642.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4DPX4@85009|Propionibacteriales	201174|Actinobacteria	E	Acetylornithine deacetylase	argE	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
gnl|extdb|FAM1414-i1-1.1_002001	754252.PFREUD_01730	1.54e-270	740.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4DN35@85009|Propionibacteriales	201174|Actinobacteria	C	oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
gnl|extdb|FAM1414-i1-1.1_002002	754252.PFREUD_01720	0.0	994.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DNI9@85009|Propionibacteriales	201174|Actinobacteria	C	Cytochrome bd terminal oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
gnl|extdb|FAM1414-i1-1.1_002003	754252.PFREUD_01710	1.93e-145	409.0	COG0847@1|root,COG0847@2|Bacteria,2GJZ0@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T,Sigma70_r4
gnl|extdb|FAM1414-i1-1.1_002005	754252.PFREUD_01690	8.16e-86	252.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4DQUT@85009|Propionibacteriales	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans	fkbP	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
gnl|extdb|FAM1414-i1-1.1_002006	754252.PFREUD_01680	8e-53	165.0	COG3592@1|root,COG3592@2|Bacteria,2II8Q@201174|Actinobacteria,4DS90@85009|Propionibacteriales	201174|Actinobacteria	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
gnl|extdb|FAM1414-i1-1.1_002008	754252.PFREUD_01660	2.63e-142	401.0	COG3548@1|root,COG3548@2|Bacteria,2IGXY@201174|Actinobacteria,4DUV8@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
gnl|extdb|FAM1414-i1-1.1_002009	754252.PFREUD_01650	1.34e-137	390.0	COG3764@1|root,COG3764@2|Bacteria,2INDK@201174|Actinobacteria	201174|Actinobacteria	M	Sortase (surface protein transpeptidase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
gnl|extdb|FAM1414-i1-1.1_002011	754252.PFREUD_01630	1.3e-155	437.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DQC2@85009|Propionibacteriales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
gnl|extdb|FAM1414-i1-1.1_002012	754252.PFREUD_01620	1.35e-203	564.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4DNEX@85009|Propionibacteriales	201174|Actinobacteria	V	COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_002013	754252.PFREUD_01610	0.0	1423.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4DWWD@85009|Propionibacteriales	201174|Actinobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
gnl|extdb|FAM1414-i1-1.1_002014	754252.PFREUD_01600	3.07e-203	562.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4DT39@85009|Propionibacteriales	201174|Actinobacteria	S	Aldo/keto reductase family	dkgA	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
gnl|extdb|FAM1414-i1-1.1_002015	754252.PFREUD_01590	7.21e-264	721.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
gnl|extdb|FAM1414-i1-1.1_002016	754252.PFREUD_01580	3.03e-190	528.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4DQSP@85009|Propionibacteriales	201174|Actinobacteria	E	Shikimate dehydrogenase substrate binding domain	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
gnl|extdb|FAM1414-i1-1.1_002017	754252.PFREUD_01570	1.23e-168	471.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4DRS8@85009|Propionibacteriales	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,LTD
gnl|extdb|FAM1414-i1-1.1_002018	754252.PFREUD_01560	3.27e-158	444.0	COG4221@1|root,COG4221@2|Bacteria,2GKK7@201174|Actinobacteria,4DRYB@85009|Propionibacteriales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
gnl|extdb|FAM1414-i1-1.1_002019	754252.PFREUD_01550	2.39e-223	620.0	COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria	201174|Actinobacteria	V	Glycopeptide antibiotics resistance protein	nnrE	-	-	-	-	-	-	-	-	-	-	-	RDD,VanZ
gnl|extdb|FAM1414-i1-1.1_002023	754252.PFREUD_01500	0.0	1411.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,4DPV3@85009|Propionibacteriales	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
gnl|extdb|FAM1414-i1-1.1_002026	754252.PFREUD_01470	2.21e-229	632.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4DNH8@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
gnl|extdb|FAM1414-i1-1.1_002027	754252.PFREUD_01460	0.0	959.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4DNHA@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
gnl|extdb|FAM1414-i1-1.1_002028	754252.PFREUD_01450	0.0	980.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
gnl|extdb|FAM1414-i1-1.1_002029	754252.PFREUD_01440	8.09e-183	508.0	COG0846@1|root,COG0846@2|Bacteria,2IJ46@201174|Actinobacteria,4DQQ7@85009|Propionibacteriales	201174|Actinobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
gnl|extdb|FAM1414-i1-1.1_002030	754252.PFREUD_01430	2.65e-113	325.0	COG2077@1|root,COG2077@2|Bacteria,2II20@201174|Actinobacteria,4DQU5@85009|Propionibacteriales	201174|Actinobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
gnl|extdb|FAM1414-i1-1.1_002031	754252.PFREUD_01420	1.27e-140	398.0	2DBY6@1|root,2ZBTG@2|Bacteria,2IM2N@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002032	754252.PFREUD_01410	1.24e-242	669.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4DP74@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
gnl|extdb|FAM1414-i1-1.1_002034	754252.PFREUD_01390	0.0	934.0	COG1236@1|root,COG1236@2|Bacteria,2HEXB@201174|Actinobacteria,4DQ4R@85009|Propionibacteriales	201174|Actinobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL
gnl|extdb|FAM1414-i1-1.1_002036	1273125.Rrhod_0805	1.29e-25	106.0	2AD8S@1|root,312XT@2|Bacteria,2I87J@201174|Actinobacteria,4FWTX@85025|Nocardiaceae	201174|Actinobacteria	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
gnl|extdb|FAM1414-i1-1.1_002037	754252.PFREUD_01350	1.94e-306	835.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4DNQN@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
gnl|extdb|FAM1414-i1-1.1_002038	754252.PFREUD_01340	0.0	1019.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4DNXQ@85009|Propionibacteriales	201174|Actinobacteria	I	diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat,PAP2
gnl|extdb|FAM1414-i1-1.1_002039	469371.Tbis_1699	3.69e-09	61.2	2E89B@1|root,332N6@2|Bacteria,2IMU0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002040	754252.PFREUD_01310	8.35e-234	644.0	COG0115@1|root,COG0115@2|Bacteria,2IAFA@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
gnl|extdb|FAM1414-i1-1.1_002041	754252.PFREUD_01300	0.0	1049.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4DPGT@85009|Propionibacteriales	201174|Actinobacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
gnl|extdb|FAM1414-i1-1.1_002042	754252.PFREUD_01290	6.46e-241	661.0	COG1893@1|root,COG1893@2|Bacteria	2|Bacteria	H	2-dehydropantoate 2-reductase activity	panE1	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
gnl|extdb|FAM1414-i1-1.1_002043	754252.PFREUD_01280	2.65e-233	648.0	COG0842@1|root,COG0842@2|Bacteria,2HEJT@201174|Actinobacteria,4DQ1W@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
gnl|extdb|FAM1414-i1-1.1_002044	754252.PFREUD_01270	0.0	1135.0	COG1129@1|root,COG1129@2|Bacteria,2I778@201174|Actinobacteria	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_002045	754252.PFREUD_01260	0.0	1026.0	COG0286@1|root,COG0286@2|Bacteria,2GKAQ@201174|Actinobacteria,4DTIH@85009|Propionibacteriales	201174|Actinobacteria	V	HsdM N-terminal domain	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
gnl|extdb|FAM1414-i1-1.1_002046	391735.Veis_2423	3.29e-87	277.0	COG0732@1|root,COG0732@2|Bacteria,1R7I5@1224|Proteobacteria,2VT2V@28216|Betaproteobacteria,4AHMY@80864|Comamonadaceae	28216|Betaproteobacteria	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
gnl|extdb|FAM1414-i1-1.1_002047	1348338.ADILRU_0465	0.0	1267.0	COG0610@1|root,COG0610@2|Bacteria,2HI69@201174|Actinobacteria,4FN77@85023|Microbacteriaceae	201174|Actinobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoR124_C,HSDR_N,ResIII
gnl|extdb|FAM1414-i1-1.1_002049	754252.PFREUD_01210	8.12e-238	652.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4DQSG@85009|Propionibacteriales	201174|Actinobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
gnl|extdb|FAM1414-i1-1.1_002051	754252.PFREUD_01040	0.0	1014.0	COG1070@1|root,COG1070@2|Bacteria,2IAKI@201174|Actinobacteria,4DTR5@85009|Propionibacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
gnl|extdb|FAM1414-i1-1.1_002052	754252.PFREUD_01050	6.71e-206	569.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4DN9T@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
gnl|extdb|FAM1414-i1-1.1_002053	754252.PFREUD_01060	8.75e-179	497.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4DQD7@85009|Propionibacteriales	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
gnl|extdb|FAM1414-i1-1.1_002054	754252.PFREUD_01070	6.13e-275	779.0	COG0515@1|root,COG0515@2|Bacteria,2GM6E@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NPCBM,Pkinase
gnl|extdb|FAM1414-i1-1.1_002055	754252.PFREUD_01080	1.86e-106	311.0	COG1388@1|root,COG1388@2|Bacteria,2GQ1M@201174|Actinobacteria	201174|Actinobacteria	M	Transglycosylase-like domain	rpfA	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	DUF3235,LysM,Transglycosylas
gnl|extdb|FAM1414-i1-1.1_002056	754252.PFREUD_01090	0.0	875.0	COG0372@1|root,COG0372@2|Bacteria,2GSH4@201174|Actinobacteria,4DWPV@85009|Propionibacteriales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
gnl|extdb|FAM1414-i1-1.1_002057	754252.PFREUD_01100	6.79e-180	502.0	28MIG@1|root,2ZAV8@2|Bacteria,2IGFB@201174|Actinobacteria,4DQAF@85009|Propionibacteriales	201174|Actinobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
gnl|extdb|FAM1414-i1-1.1_002058	2074.JNYD01000004_gene4841	3.03e-05	51.2	COG5658@1|root,COG5658@2|Bacteria,2GR16@201174|Actinobacteria,4E4YP@85010|Pseudonocardiales	201174|Actinobacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
gnl|extdb|FAM1414-i1-1.1_002059	754252.PFREUD_01120	0.0	974.0	COG1404@1|root,COG1404@2|Bacteria,2GMBS@201174|Actinobacteria	201174|Actinobacteria	O	cog cog1404	vpr	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
gnl|extdb|FAM1414-i1-1.1_002060	754252.PFREUD_01130	3.52e-274	750.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4DNHM@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
gnl|extdb|FAM1414-i1-1.1_002061	754252.PFREUD_01140	0.0	926.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4DNHQ@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
gnl|extdb|FAM1414-i1-1.1_002062	754252.PFREUD_01150	1.07e-74	223.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR1	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
gnl|extdb|FAM1414-i1-1.1_002063	762963.HMPREF9056_02856	2.3e-69	224.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4D53J@85005|Actinomycetales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
gnl|extdb|FAM1414-i1-1.1_001941	754252.PFREUD_02530	4.33e-148	417.0	COG2949@1|root,COG2949@2|Bacteria,2GWVK@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
gnl|extdb|FAM1414-i1-1.1_001959	754252.PFREUD_02270	1.07e-125	357.0	2BBAF@1|root,324T6@2|Bacteria,2IM1Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001969	754252.PFREUD_02170	0.0	972.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4DNHS@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
gnl|extdb|FAM1414-i1-1.1_001980	754252.PFREUD_02130	0.0	932.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	aroP	-	-	ko:K03293,ko:K11732	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.1	-	-	AA_permease
gnl|extdb|FAM1414-i1-1.1_001993	754252.PFREUD_01840	0.0	2401.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,2I995@201174|Actinobacteria,4DVUV@85009|Propionibacteriales	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
gnl|extdb|FAM1414-i1-1.1_001992	754252.PFREUD_01850	3.13e-240	663.0	COG0167@1|root,COG0167@2|Bacteria,2GN1V@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
gnl|extdb|FAM1414-i1-1.1_001999	754252.PFREUD_01740	0.0	1168.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4DP3V@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_002004	754252.PFREUD_01700	1.54e-133	380.0	COG0572@1|root,COG0572@2|Bacteria,2I9H4@201174|Actinobacteria,4DR2H@85009|Propionibacteriales	201174|Actinobacteria	F	Fructose transport system kinase	frcK	-	-	-	-	-	-	-	-	-	-	-	PRK
gnl|extdb|FAM1414-i1-1.1_002007	754252.PFREUD_01670	6.25e-50	160.0	COG2388@1|root,COG2388@2|Bacteria	2|Bacteria	S	GCN5-related N-acetyl-transferase	-	-	2.7.7.76	ko:K06975,ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_CG
gnl|extdb|FAM1414-i1-1.1_002010	754252.PFREUD_01640	6.14e-305	832.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4DN2N@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
gnl|extdb|FAM1414-i1-1.1_002033	754252.PFREUD_01400	3.29e-148	418.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DNSE@85009|Propionibacteriales	201174|Actinobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
gnl|extdb|FAM1414-i1-1.1_002048	754252.PFREUD_01220	1.71e-201	568.0	COG0847@1|root,COG0847@2|Bacteria,2IFVF@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
gnl|extdb|FAM1414-i1-1.1_002065	754252.PFREUD_10670	0.0	1730.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4DPQE@85009|Propionibacteriales	201174|Actinobacteria	G	Protein of unknown function (DUF3417)	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
gnl|extdb|FAM1414-i1-1.1_002066	754252.PFREUD_10660	0.0	1399.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4DMZD@85009|Propionibacteriales	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
gnl|extdb|FAM1414-i1-1.1_002068	754252.PFREUD_10640	0.0	913.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4DNWM@85009|Propionibacteriales	201174|Actinobacteria	G	protein probably involved in trehalose biosynthesis	mak	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
gnl|extdb|FAM1414-i1-1.1_002070	754252.PFREUD_10620	1.51e-189	526.0	COG1051@1|root,COG1051@2|Bacteria,2IFB9@201174|Actinobacteria,4DWZM@85009|Propionibacteriales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_002071	754252.PFREUD_10610	0.0	1100.0	COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4DNWG@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
gnl|extdb|FAM1414-i1-1.1_002072	754252.PFREUD_10600	5.94e-217	601.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4DN3B@85009|Propionibacteriales	201174|Actinobacteria	O	Tetratricopeptide repeat	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
gnl|extdb|FAM1414-i1-1.1_002073	754252.PFREUD_10590	2.26e-108	311.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4DQPV@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
gnl|extdb|FAM1414-i1-1.1_002074	754252.PFREUD_10580	2.77e-139	393.0	COG0204@1|root,COG0204@2|Bacteria,2IDC7@201174|Actinobacteria,4DRMR@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
gnl|extdb|FAM1414-i1-1.1_002075	754252.PFREUD_10570	3.41e-143	434.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K02107	ko00190,map00190	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	DivIVA
gnl|extdb|FAM1414-i1-1.1_002076	754252.PFREUD_10560	9.9e-168	470.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4DN0H@85009|Propionibacteriales	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
gnl|extdb|FAM1414-i1-1.1_002078	754252.PFREUD_10540	2.52e-200	554.0	COG2267@1|root,COG2267@2|Bacteria,2I5QQ@201174|Actinobacteria,4DWZK@85009|Propionibacteriales	201174|Actinobacteria	I	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
gnl|extdb|FAM1414-i1-1.1_002079	754252.PFREUD_10530	1.16e-141	400.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,4DNZ5@85009|Propionibacteriales	201174|Actinobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
gnl|extdb|FAM1414-i1-1.1_002081	1122994.AUFR01000001_gene1457	1.92e-23	96.7	2E6YX@1|root,331I5@2|Bacteria,2ISED@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2550)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2550
gnl|extdb|FAM1414-i1-1.1_002082	754252.PFREUD_10500	1.14e-100	292.0	COG0355@1|root,COG0355@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
gnl|extdb|FAM1414-i1-1.1_002083	754252.PFREUD_10490	0.0	956.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4DMY1@85009|Propionibacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
gnl|extdb|FAM1414-i1-1.1_002084	754252.PFREUD_10480	1.71e-211	585.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4DN4I@85009|Propionibacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
gnl|extdb|FAM1414-i1-1.1_002085	754252.PFREUD_10470	0.0	1051.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4DNCI@85009|Propionibacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
gnl|extdb|FAM1414-i1-1.1_002086	754252.PFREUD_10460	1.01e-177	496.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
gnl|extdb|FAM1414-i1-1.1_002087	754252.PFREUD_10450	1.05e-101	297.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4DQDT@85009|Propionibacteriales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
gnl|extdb|FAM1414-i1-1.1_002088	754252.PFREUD_10440	4.52e-41	135.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
gnl|extdb|FAM1414-i1-1.1_002090	754252.PFREUD_10420	2.45e-48	154.0	COG5336@1|root,COG5336@2|Bacteria	2|Bacteria	C	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
gnl|extdb|FAM1414-i1-1.1_002092	754252.PFREUD_10390	7.13e-256	703.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4DPQZ@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
gnl|extdb|FAM1414-i1-1.1_002095	754252.PFREUD_10360	1.31e-246	678.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4DP4Q@85009|Propionibacteriales	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
gnl|extdb|FAM1414-i1-1.1_002096	754252.PFREUD_10350	8.86e-51	160.0	COG0254@1|root,COG0254@2|Bacteria	2|Bacteria	J	rRNA binding	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
gnl|extdb|FAM1414-i1-1.1_002097	754252.PFREUD_10340	0.0	1091.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4DN0N@85009|Propionibacteriales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
gnl|extdb|FAM1414-i1-1.1_002098	754252.PFREUD_10330	6.97e-150	421.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
gnl|extdb|FAM1414-i1-1.1_002099	754252.PFREUD_10320	1.96e-310	847.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4DPCG@85009|Propionibacteriales	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
gnl|extdb|FAM1414-i1-1.1_002100	754252.PFREUD_10300	0.0	938.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4DPUN@85009|Propionibacteriales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
gnl|extdb|FAM1414-i1-1.1_002102	754252.PFREUD_10290	3.13e-134	391.0	COG0586@1|root,COG0586@2|Bacteria,2GKKC@201174|Actinobacteria,4DUMN@85009|Propionibacteriales	201174|Actinobacteria	S	SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
gnl|extdb|FAM1414-i1-1.1_002103	754252.PFREUD_10280	0.0	907.0	COG5650@1|root,COG5650@2|Bacteria,2GN1J@201174|Actinobacteria,4DRA3@85009|Propionibacteriales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
gnl|extdb|FAM1414-i1-1.1_002104	754252.PFREUD_10270	3.66e-310	845.0	COG5650@1|root,COG5650@2|Bacteria,2GN1J@201174|Actinobacteria,4DRA3@85009|Propionibacteriales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
gnl|extdb|FAM1414-i1-1.1_002105	754252.PFREUD_10260	0.0	897.0	COG5650@1|root,COG5650@2|Bacteria,2GN1J@201174|Actinobacteria,4DRA3@85009|Propionibacteriales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
gnl|extdb|FAM1414-i1-1.1_002106	754252.PFREUD_10250	0.0	2467.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4DN7Q@85009|Propionibacteriales	201174|Actinobacteria	C	2-oxoglutarate dehydrogenase	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
gnl|extdb|FAM1414-i1-1.1_002107	754252.PFREUD_10240	7.13e-56	173.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4DRG4@85009|Propionibacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
gnl|extdb|FAM1414-i1-1.1_002108	754252.PFREUD_10230	0.0	986.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4DPYA@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
gnl|extdb|FAM1414-i1-1.1_002109	754252.PFREUD_10210	1.3e-67	204.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
gnl|extdb|FAM1414-i1-1.1_002111	754252.PFREUD_10190	3.72e-189	524.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4DPFJ@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
gnl|extdb|FAM1414-i1-1.1_002112	754252.PFREUD_10180	0.0	882.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4DNC2@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
gnl|extdb|FAM1414-i1-1.1_002113	754252.PFREUD_10170	6.46e-259	709.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria,4DNJ3@85009|Propionibacteriales	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
gnl|extdb|FAM1414-i1-1.1_002114	754252.PFREUD_10160	2.33e-198	549.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4DNRF@85009|Propionibacteriales	201174|Actinobacteria	G	Inositol monophosphatase family	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
gnl|extdb|FAM1414-i1-1.1_002115	754252.PFREUD_10150	4.23e-188	548.0	arCOG08054@1|root,2Z8AD@2|Bacteria,2GKIT@201174|Actinobacteria	201174|Actinobacteria	S	Carbohydrate-binding domain-containing protein Cthe_2159	-	-	-	-	-	-	-	-	-	-	-	-	Cthe_2159
gnl|extdb|FAM1414-i1-1.1_002116	754252.PFREUD_10140	8.09e-194	537.0	COG3025@1|root,COG3025@2|Bacteria,2II2C@201174|Actinobacteria,4DV8T@85009|Propionibacteriales	201174|Actinobacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
gnl|extdb|FAM1414-i1-1.1_002117	754252.PFREUD_10130	3.52e-136	387.0	arCOG14808@1|root,308PC@2|Bacteria,2IIBU@201174|Actinobacteria,4DSEE@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
gnl|extdb|FAM1414-i1-1.1_002118	754252.PFREUD_10120	3.92e-219	605.0	COG4632@1|root,COG4632@2|Bacteria	2|Bacteria	-	-	XK27_08080	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	NAGPA
gnl|extdb|FAM1414-i1-1.1_002119	446469.Sked_32660	9.2e-44	156.0	COG1215@1|root,COG2246@1|root,COG1215@2|Bacteria,COG2246@2|Bacteria,2I6D1@201174|Actinobacteria	201174|Actinobacteria	M	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
gnl|extdb|FAM1414-i1-1.1_002120	1449044.JMLE01000001_gene3837	4.69e-44	158.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,2I6D1@201174|Actinobacteria,1WASN@1268|Micrococcaceae	201174|Actinobacteria	M	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
gnl|extdb|FAM1414-i1-1.1_002121	754252.PFREUD_10080	8.13e-283	773.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4DPHP@85009|Propionibacteriales	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
gnl|extdb|FAM1414-i1-1.1_002122	754252.PFREUD_10070	2.47e-186	519.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DX37@85009|Propionibacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
gnl|extdb|FAM1414-i1-1.1_002123	754252.PFREUD_10060	4.86e-198	549.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
gnl|extdb|FAM1414-i1-1.1_002124	754252.PFREUD_10050	1.43e-183	511.0	COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria	201174|Actinobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC4	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002125	754252.PFREUD_10040	3.68e-193	540.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4DPAR@85009|Propionibacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppB4	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002126	754252.PFREUD_10030	0.0	1004.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
gnl|extdb|FAM1414-i1-1.1_002128	754252.PFREUD_10010	1.24e-278	761.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4DQ0R@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
gnl|extdb|FAM1414-i1-1.1_002129	754252.PFREUD_10000	5.8e-66	200.0	COG2388@1|root,COG2388@2|Bacteria	2|Bacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
gnl|extdb|FAM1414-i1-1.1_002130	754252.PFREUD_09990	1.37e-310	845.0	COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria,4DNTP@85009|Propionibacteriales	201174|Actinobacteria	S	Alpha beta hydrolase	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
gnl|extdb|FAM1414-i1-1.1_002132	754252.PFREUD_09970	0.0	891.0	COG0612@1|root,COG0612@2|Bacteria,2GKAT@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
gnl|extdb|FAM1414-i1-1.1_002133	754252.PFREUD_09960	0.0	1918.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4DQ0K@85009|Propionibacteriales	201174|Actinobacteria	T	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
gnl|extdb|FAM1414-i1-1.1_002135	754252.PFREUD_09940	2.62e-240	661.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4DQEN@85009|Propionibacteriales	201174|Actinobacteria	T	Domain present in PSD-95, Dlg, and ZO-1/2.	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
gnl|extdb|FAM1414-i1-1.1_002138	754252.PFREUD_09900	2.43e-31	110.0	2E479@1|root,32Z35@2|Bacteria,2GQXY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002139	258052.JNYV01000004_gene4395	5.31e-06	55.8	COG0476@1|root,COG0476@2|Bacteria,2GMJI@201174|Actinobacteria,2M1BV@2063|Kitasatospora	201174|Actinobacteria	H	UBA ThiF-type NAD FAD binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
gnl|extdb|FAM1414-i1-1.1_002141	754252.PFREUD_09860	0.0	2255.0	COG1330@1|root,COG1330@2|Bacteria,2GNVB@201174|Actinobacteria,4DNIF@85009|Propionibacteriales	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
gnl|extdb|FAM1414-i1-1.1_002142	754252.PFREUD_09850	0.0	2189.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4DNNK@85009|Propionibacteriales	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
gnl|extdb|FAM1414-i1-1.1_002143	754252.PFREUD_09840	0.0	1183.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DWT0@85009|Propionibacteriales	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
gnl|extdb|FAM1414-i1-1.1_002144	754252.PFREUD_09830	2.56e-219	604.0	COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4DN72@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	nudC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
gnl|extdb|FAM1414-i1-1.1_002145	754252.PFREUD_09820	0.0	2174.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4DP1P@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
gnl|extdb|FAM1414-i1-1.1_002146	754252.PFREUD_09810	0.0	2193.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4DPY8@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
gnl|extdb|FAM1414-i1-1.1_002147	754252.PFREUD_09800	1.23e-43	141.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
gnl|extdb|FAM1414-i1-1.1_002148	754252.PFREUD_09790	5.96e-206	570.0	COG0631@1|root,COG0631@2|Bacteria,2GKDM@201174|Actinobacteria,4DN5I@85009|Propionibacteriales	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	prpB10	-	-	-	-	-	-	-	-	-	-	-	DZR,PP2C_2
gnl|extdb|FAM1414-i1-1.1_002149	754252.PFREUD_09780	9.66e-46	147.0	2E3M2@1|root,32YJA@2|Bacteria,2GQQW@201174|Actinobacteria,4DS75@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
gnl|extdb|FAM1414-i1-1.1_002150	754252.PFREUD_09770	4.29e-175	488.0	COG3396@1|root,COG3396@2|Bacteria,2GKXZ@201174|Actinobacteria,4DMYE@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
gnl|extdb|FAM1414-i1-1.1_002151	754252.PFREUD_09760	0.0	937.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DNNT@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
gnl|extdb|FAM1414-i1-1.1_002152	754252.PFREUD_09750	1.22e-271	743.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4DTIS@85009|Propionibacteriales	201174|Actinobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
gnl|extdb|FAM1414-i1-1.1_002153	754252.PFREUD_09740	1.72e-211	584.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4DP8Q@85009|Propionibacteriales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
gnl|extdb|FAM1414-i1-1.1_002154	754252.PFREUD_09730	2.69e-114	327.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
gnl|extdb|FAM1414-i1-1.1_002156	754252.PFREUD_09710	3.33e-118	338.0	2DGDU@1|root,2ZVJF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002157	1136417.AZWE01000007_gene1999	7.01e-05	48.1	2EUNN@1|root,33N4H@2|Bacteria,2IN6S@201174|Actinobacteria,4DE0R@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002159	754252.PFREUD_09680	1.25e-134	382.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4DQCT@85009|Propionibacteriales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
gnl|extdb|FAM1414-i1-1.1_002160	754252.PFREUD_09670	1.57e-195	541.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	ctsW	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
gnl|extdb|FAM1414-i1-1.1_002161	754252.PFREUD_09660	1.76e-176	491.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DP53@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
gnl|extdb|FAM1414-i1-1.1_002162	754252.PFREUD_09650	1.22e-136	386.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4DR8I@85009|Propionibacteriales	201174|Actinobacteria	K	Uncharacterized ACR, COG1678	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
gnl|extdb|FAM1414-i1-1.1_002164	754252.PFREUD_09640	8.36e-146	411.0	COG3296@1|root,COG3296@2|Bacteria,2GT71@201174|Actinobacteria,4DSEG@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4870
gnl|extdb|FAM1414-i1-1.1_002165	754252.PFREUD_09630	5.61e-108	311.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4DQQA@85009|Propionibacteriales	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
gnl|extdb|FAM1414-i1-1.1_002166	754252.PFREUD_09620	0.0	1195.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
gnl|extdb|FAM1414-i1-1.1_002167	754252.PFREUD_09610	5.93e-226	634.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4DPWU@85009|Propionibacteriales	201174|Actinobacteria	M	Peptidase family M23	pdc2	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
gnl|extdb|FAM1414-i1-1.1_002169	754252.PFREUD_09590	1.28e-160	450.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4DNHN@85009|Propionibacteriales	201174|Actinobacteria	D	cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_002170	754252.PFREUD_09580	7.45e-258	707.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4DPCH@85009|Propionibacteriales	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
gnl|extdb|FAM1414-i1-1.1_002171	754252.PFREUD_09570	2.39e-92	271.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4DR27@85009|Propionibacteriales	201174|Actinobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
gnl|extdb|FAM1414-i1-1.1_002174	1229781.C272_06154	6.29e-157	456.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4FAPH@85019|Brevibacteriaceae	201174|Actinobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
gnl|extdb|FAM1414-i1-1.1_002176	1229781.C272_06164	1.72e-151	427.0	2EYJK@1|root,33RTA@2|Bacteria,2IE6T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002177	926564.KI911656_gene1659	9.48e-67	206.0	COG2453@1|root,COG2453@2|Bacteria,2IHXA@201174|Actinobacteria	201174|Actinobacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase
gnl|extdb|FAM1414-i1-1.1_002178	478801.Ksed_08050	0.0	1597.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
gnl|extdb|FAM1414-i1-1.1_002179	1151122.AQYD01000004_gene2736	5.22e-140	404.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4FKAS@85023|Microbacteriaceae	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
gnl|extdb|FAM1414-i1-1.1_002180	1449058.JQKT01000014_gene2355	1.76e-204	572.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4FN8P@85023|Microbacteriaceae	201174|Actinobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
gnl|extdb|FAM1414-i1-1.1_002181	1151122.AQYD01000004_gene2737	6.11e-52	169.0	2E60Y@1|root,330Q9@2|Bacteria,2GTR2@201174|Actinobacteria,4FT5V@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002182	1397278.AYMV01000021_gene1775	7.08e-42	142.0	2BJHU@1|root,32DUR@2|Bacteria,2GYU1@201174|Actinobacteria,4FQPP@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002183	1397278.AYMV01000021_gene1774	8.7e-102	299.0	COG1302@1|root,COG1302@2|Bacteria,2IQBU@201174|Actinobacteria,4FNZK@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
gnl|extdb|FAM1414-i1-1.1_002184	1122238.AULR01000008_gene847	2.13e-96	284.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4FNE9@85023|Microbacteriaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
gnl|extdb|FAM1414-i1-1.1_002185	1397278.AYMV01000021_gene1773	3.42e-50	159.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria,4FQ3U@85023|Microbacteriaceae	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
gnl|extdb|FAM1414-i1-1.1_002186	1452536.JARE01000016_gene2134	2.56e-18	77.0	COG3237@1|root,COG3237@2|Bacteria,2GQQ4@201174|Actinobacteria,4FQH1@85023|Microbacteriaceae	201174|Actinobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
gnl|extdb|FAM1414-i1-1.1_002187	1397278.AYMV01000021_gene1771	1.3e-32	114.0	2B5QM@1|root,31YK6@2|Bacteria,2H0X2@201174|Actinobacteria,4FQMR@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002188	1397278.AYMV01000021_gene1770	1.23e-94	281.0	2FGZC@1|root,34C09@2|Bacteria,2IJ32@201174|Actinobacteria,4FP08@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002189	1397278.AYMV01000021_gene1769	3.25e-91	271.0	2BXHQ@1|root,345PG@2|Bacteria,2GRQ5@201174|Actinobacteria,4FQE1@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002190	1122238.AULR01000008_gene852	3.03e-41	140.0	2AYMZ@1|root,31QSF@2|Bacteria,2HSX0@201174|Actinobacteria,4FQQX@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002191	1122238.AULR01000008_gene853	5.01e-23	89.4	2DED3@1|root,2ZMH1@2|Bacteria,2GXTN@201174|Actinobacteria,4FQMZ@85023|Microbacteriaceae	201174|Actinobacteria	S	Small integral membrane protein (DUF2273)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2273
gnl|extdb|FAM1414-i1-1.1_002195	1074488.AGBX01000007_gene1502	4.91e-19	81.3	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4FCZ7@85020|Dermabacteraceae	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_002067	754252.PFREUD_10650	0.0	1214.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4DNMJ@85009|Propionibacteriales	201174|Actinobacteria	G	Trehalose synthase	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
gnl|extdb|FAM1414-i1-1.1_002069	754252.PFREUD_10630	0.0	1357.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4DPZS@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
gnl|extdb|FAM1414-i1-1.1_002077	706439.HMPREF9057_00636	1.07e-14	68.6	2E3EP@1|root,32AF8@2|Bacteria,2HM0U@201174|Actinobacteria,4D65U@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002080	754252.PFREUD_10520	6.06e-255	699.0	COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4DP41@85009|Propionibacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
gnl|extdb|FAM1414-i1-1.1_002089	754252.PFREUD_10430	1.74e-191	532.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4DPUV@85009|Propionibacteriales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
gnl|extdb|FAM1414-i1-1.1_002093	754252.PFREUD_10380	6.34e-187	521.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4DQKX@85009|Propionibacteriales	201174|Actinobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
gnl|extdb|FAM1414-i1-1.1_002094	754252.PFREUD_10370	2.3e-204	565.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4DP23@85009|Propionibacteriales	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	Cons_hypoth95,MTS,Methyltransf_31
gnl|extdb|FAM1414-i1-1.1_002110	754252.PFREUD_10200	1.21e-131	375.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DMYC@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
gnl|extdb|FAM1414-i1-1.1_002131	754252.PFREUD_09980	6.71e-295	805.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
gnl|extdb|FAM1414-i1-1.1_002134	754252.PFREUD_09950	7.09e-132	374.0	2DA1Q@1|root,32TUF@2|Bacteria,2GKR3@201174|Actinobacteria,4DRDD@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002136	754252.PFREUD_09920	0.0	905.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4DN9A@85009|Propionibacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
gnl|extdb|FAM1414-i1-1.1_002137	754252.PFREUD_09910	2.92e-129	368.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4DQV0@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
gnl|extdb|FAM1414-i1-1.1_002140	754252.PFREUD_09880	0.0	1375.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4DNWV@85009|Propionibacteriales	201174|Actinobacteria	L	HRDC domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
gnl|extdb|FAM1414-i1-1.1_002158	754252.PFREUD_09690	0.0	1830.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4DPEU@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
gnl|extdb|FAM1414-i1-1.1_002168	754252.PFREUD_09600	6.63e-197	547.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4DQWR@85009|Propionibacteriales	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
gnl|extdb|FAM1414-i1-1.1_002173	1122998.AUHZ01000010_gene1471	2.88e-158	451.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
gnl|extdb|FAM1414-i1-1.1_002192	1397278.AYMV01000021_gene1767	3.53e-74	225.0	COG1302@1|root,COG1302@2|Bacteria,2IMA3@201174|Actinobacteria,4FNY9@85023|Microbacteriaceae	201174|Actinobacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
gnl|extdb|FAM1414-i1-1.1_002194	1122175.ATXU01000001_gene1126	1.36e-217	605.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4FKHE@85023|Microbacteriaceae	201174|Actinobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
gnl|extdb|FAM1414-i1-1.1_002196	754252.PFREUD_24680	3.1e-118	345.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DUKR@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve,rve_3
gnl|extdb|FAM1414-i1-1.1_002198	754252.PFREUD_20790	7.03e-44	142.0	COG2608@1|root,COG2608@2|Bacteria,2GQK5@201174|Actinobacteria,4DSND@85009|Propionibacteriales	201174|Actinobacteria	P	Heavy-metal-associated domain	copZ	-	-	-	-	-	-	-	-	-	-	-	HMA
gnl|extdb|FAM1414-i1-1.1_002200	754252.PFREUD_20810	0.0	870.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4DN0Y@85009|Propionibacteriales	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
gnl|extdb|FAM1414-i1-1.1_002201	1416759.AYMR01000011_gene527	5.98e-67	211.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4FND1@85023|Microbacteriaceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
gnl|extdb|FAM1414-i1-1.1_002202	1416759.AYMR01000011_gene528	4.28e-65	221.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4FNMT@85023|Microbacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
gnl|extdb|FAM1414-i1-1.1_002203	1032480.MLP_38510	3.2e-144	434.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DP72@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_002204	754252.PFREUD_20820	2.91e-110	318.0	COG1846@1|root,COG1846@2|Bacteria,2GQS5@201174|Actinobacteria	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
gnl|extdb|FAM1414-i1-1.1_002205	754252.PFREUD_20830	3.12e-309	847.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4DNV0@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K18926	-	M00715	-	-	ko00000,ko00002,ko02000	2.A.1.3.30	-	-	CBS,MFS_1
gnl|extdb|FAM1414-i1-1.1_002206	754252.PFREUD_20840	1.3e-269	738.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4DP05@85009|Propionibacteriales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
gnl|extdb|FAM1414-i1-1.1_002207	754252.PFREUD_20850	6.93e-196	543.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4DP7U@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
gnl|extdb|FAM1414-i1-1.1_002210	754252.PFREUD_20880	3.26e-74	222.0	2EP9H@1|root,33GW8@2|Bacteria,2HBUH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
gnl|extdb|FAM1414-i1-1.1_002211	754252.PFREUD_20890	4.61e-291	795.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4DVC5@85009|Propionibacteriales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
gnl|extdb|FAM1414-i1-1.1_002212	754252.PFREUD_20900	0.0	1241.0	COG0422@1|root,COG0422@2|Bacteria,2GJ3Y@201174|Actinobacteria,4DN8A@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
gnl|extdb|FAM1414-i1-1.1_002213	754252.PFREUD_20910	0.0	1082.0	COG0591@1|root,COG0591@2|Bacteria,2GKPW@201174|Actinobacteria,4DNA9@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
gnl|extdb|FAM1414-i1-1.1_002214	754252.PFREUD_20920	2.45e-114	328.0	2EJED@1|root,33D5D@2|Bacteria,2GUI5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002215	754252.PFREUD_20940	5.66e-158	443.0	COG1321@1|root,COG1321@2|Bacteria,2GK7P@201174|Actinobacteria,4DVDS@85009|Propionibacteriales	201174|Actinobacteria	K	FeoA	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
gnl|extdb|FAM1414-i1-1.1_002216	754252.PFREUD_20950	8.83e-317	865.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4DSP2@85009|Propionibacteriales	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	mntH	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0030001,GO:0034220,GO:0034755,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071421,GO:0071577,GO:0071578,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
gnl|extdb|FAM1414-i1-1.1_002218	1122997.AUDD01000034_gene1939	1.7e-15	80.5	2DTHT@1|root,33KE8@2|Bacteria,2I02E@201174|Actinobacteria,4DV28@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002219	754252.PFREUD_20980	6.73e-202	561.0	COG2304@1|root,COG2304@2|Bacteria,2GJMP@201174|Actinobacteria	201174|Actinobacteria	S	von willebrand factor type a	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
gnl|extdb|FAM1414-i1-1.1_002221	1121933.AUHH01000001_gene2079	2.22e-181	520.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,2GN33@201174|Actinobacteria,4DQMY@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
gnl|extdb|FAM1414-i1-1.1_002222	1120797.KB908256_gene2150	4.91e-243	687.0	COG4986@1|root,COG4986@2|Bacteria,2GNF7@201174|Actinobacteria,238I1@1762|Mycobacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002224	1171373.PACID_00890	7.58e-148	449.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,2HXN0@201174|Actinobacteria	201174|Actinobacteria	GKT	transcriptional antiterminator	-	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
gnl|extdb|FAM1414-i1-1.1_002225	267747.PPA0021	1.48e-32	120.0	COG1762@1|root,COG1762@2|Bacteria,2H0MP@201174|Actinobacteria	201174|Actinobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.200	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_EIIA_2
gnl|extdb|FAM1414-i1-1.1_002226	1462527.CCDM010000001_gene1962	1.48e-52	175.0	COG0235@1|root,COG0235@2|Bacteria,1V3MT@1239|Firmicutes,4HI2W@91061|Bacilli	91061|Bacilli	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
gnl|extdb|FAM1414-i1-1.1_002227	765123.HMPREF9621_02737	2.2e-200	566.0	COG3775@1|root,COG3775@2|Bacteria,2IBG5@201174|Actinobacteria	201174|Actinobacteria	G	PTS system Galactitol-specific IIC component	-	-	-	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5.1	-	-	EIIC-GAT
gnl|extdb|FAM1414-i1-1.1_002228	1171373.PACID_00910	5.87e-43	142.0	COG3414@1|root,COG3414@2|Bacteria,2H8V1@201174|Actinobacteria	201174|Actinobacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.200	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_IIB
gnl|extdb|FAM1414-i1-1.1_002229	1171373.PACID_00900	4.21e-173	492.0	COG1063@1|root,COG1063@2|Bacteria,2GKBE@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	adh	-	1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
gnl|extdb|FAM1414-i1-1.1_002230	1111131.HMPREF1255_0851	1.22e-31	118.0	2C94N@1|root,33BC5@2|Bacteria,2GS64@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002231	367299.JOEE01000006_gene755	5.01e-265	736.0	COG0286@1|root,COG0286@2|Bacteria,2GP6Y@201174|Actinobacteria,4FG4F@85021|Intrasporangiaceae	201174|Actinobacteria	V	HsdM N-terminal domain	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
gnl|extdb|FAM1414-i1-1.1_002232	585531.HMPREF0063_11123	4.31e-86	273.0	COG0732@1|root,COG0732@2|Bacteria,2IN0M@201174|Actinobacteria	201174|Actinobacteria	V	Type I restriction modification DNA specificity domain	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
gnl|extdb|FAM1414-i1-1.1_002233	585531.HMPREF0063_11125	0.0	1413.0	COG4096@1|root,COG4096@2|Bacteria,2I2FC@201174|Actinobacteria	201174|Actinobacteria	L	Type III restriction enzyme res subunit	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
gnl|extdb|FAM1414-i1-1.1_002234	558173.CDOO_00865	2.58e-70	226.0	COG0758@1|root,COG0758@2|Bacteria,2IFTH@201174|Actinobacteria,22NA7@1653|Corynebacteriaceae	201174|Actinobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
gnl|extdb|FAM1414-i1-1.1_002235	754252.PFREUD_21420	4.24e-221	614.0	COG2310@1|root,COG2310@2|Bacteria,2IE9A@201174|Actinobacteria	201174|Actinobacteria	T	stress, protein	-	-	-	-	-	-	-	-	-	-	-	-	TerD
gnl|extdb|FAM1414-i1-1.1_002236	754252.PFREUD_21430	0.0	960.0	COG0471@1|root,COG0471@2|Bacteria,2GVHZ@201174|Actinobacteria	201174|Actinobacteria	P	transporter	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
gnl|extdb|FAM1414-i1-1.1_002237	754252.PFREUD_21440	4.41e-88	260.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4DQTS@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
gnl|extdb|FAM1414-i1-1.1_002238	754252.PFREUD_21450	0.0	885.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4DNA4@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2,Lum_binding
gnl|extdb|FAM1414-i1-1.1_002239	754252.PFREUD_21460	1.09e-148	419.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4DQ6E@85009|Propionibacteriales	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
gnl|extdb|FAM1414-i1-1.1_002242	754252.PFREUD_21490	8.95e-105	303.0	COG1447@1|root,COG1447@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	lacF	-	2.7.1.196,2.7.1.205,2.7.1.207	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	M00275,M00281	R04393,R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.1,4.A.3.2	-	-	PTS_IIA
gnl|extdb|FAM1414-i1-1.1_002243	754252.PFREUD_21500	0.0	1332.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria	201174|Actinobacteria	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
gnl|extdb|FAM1414-i1-1.1_002244	1032480.MLP_46690	7.47e-59	198.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4DR6P@85009|Propionibacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
gnl|extdb|FAM1414-i1-1.1_002245	754252.PFREUD_21530	0.0	905.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria	201174|Actinobacteria	C	the transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
gnl|extdb|FAM1414-i1-1.1_002246	754252.PFREUD_21540	0.0	953.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4DNG1@85009|Propionibacteriales	201174|Actinobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
gnl|extdb|FAM1414-i1-1.1_002247	754252.PFREUD_21550	1.7e-207	578.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	effR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
gnl|extdb|FAM1414-i1-1.1_002248	754252.PFREUD_21560	3.26e-234	647.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DNPQ@85009|Propionibacteriales	201174|Actinobacteria	V	daunorubicin resistance ABC transporter	drrA	-	-	ko:K01990,ko:K18232	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC_tran,DUF4162
gnl|extdb|FAM1414-i1-1.1_002249	754252.PFREUD_21570	2.14e-160	453.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4DPYQ@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	drrB	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
gnl|extdb|FAM1414-i1-1.1_002250	754252.PFREUD_21580	1.6e-247	680.0	COG1118@1|root,COG1118@2|Bacteria,2I3KJ@201174|Actinobacteria,4DNAR@85009|Propionibacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0040007,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE,TOBE_3
gnl|extdb|FAM1414-i1-1.1_002252	754252.PFREUD_21600	1.13e-217	605.0	COG0555@1|root,COG0555@2|Bacteria,2GP6P@201174|Actinobacteria,4DNC9@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002253	754252.PFREUD_21610	2.52e-245	675.0	COG1613@1|root,COG1613@2|Bacteria,2GJIK@201174|Actinobacteria,4DNI4@85009|Propionibacteriales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	subI	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
gnl|extdb|FAM1414-i1-1.1_002254	754252.PFREUD_21620	0.0	1181.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4DP25@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	sir	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
gnl|extdb|FAM1414-i1-1.1_002255	754252.PFREUD_21630	6.48e-183	508.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4DPGD@85009|Propionibacteriales	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2392	PAPS_reduct
gnl|extdb|FAM1414-i1-1.1_002257	754252.PFREUD_21650	0.0	870.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4DPIP@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
gnl|extdb|FAM1414-i1-1.1_002258	754252.PFREUD_21660	3.95e-108	311.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
gnl|extdb|FAM1414-i1-1.1_002259	754252.PFREUD_21670	2.72e-170	474.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
gnl|extdb|FAM1414-i1-1.1_002260	754252.PFREUD_21680	1.21e-172	483.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,4DPSU@85009|Propionibacteriales	201174|Actinobacteria	S	VIT family	pcl	-	-	-	-	-	-	-	-	-	-	-	VIT1
gnl|extdb|FAM1414-i1-1.1_002261	754252.PFREUD_21690	0.0	1001.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4DN9N@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
gnl|extdb|FAM1414-i1-1.1_002262	754252.PFREUD_21700	0.0	2900.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2I1VH@201174|Actinobacteria,4DVSF@85009|Propionibacteriales	201174|Actinobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
gnl|extdb|FAM1414-i1-1.1_002265	1171373.PACID_02570	2.61e-94	285.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,4DQXM@85009|Propionibacteriales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
gnl|extdb|FAM1414-i1-1.1_002266	1120942.AUBM01000003_gene804	1.77e-60	192.0	COG0521@1|root,COG0521@2|Bacteria,2H57U@201174|Actinobacteria,4D434@85005|Actinomycetales	201174|Actinobacteria	H	Molybdopterin binding domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
gnl|extdb|FAM1414-i1-1.1_002267	1122994.AUFR01000011_gene1978	9.13e-64	203.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
gnl|extdb|FAM1414-i1-1.1_002270	1227261.HMPREF0043_01372	0.0	2070.0	COG5013@1|root,COG5013@2|Bacteria,2GKZU@201174|Actinobacteria,4D4NX@85005|Actinomycetales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding
gnl|extdb|FAM1414-i1-1.1_002271	1203556.HMPREF1478_00889	0.0	880.0	COG1140@1|root,COG1140@2|Bacteria,2GJ8P@201174|Actinobacteria,4D4CE@85005|Actinomycetales	201174|Actinobacteria	C	Nitrate reductase beta subunit	narH	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
gnl|extdb|FAM1414-i1-1.1_002273	649743.HMPREF0972_01555	3.3e-125	361.0	COG2181@1|root,COG2181@2|Bacteria,2GJVI@201174|Actinobacteria,4D3AB@85005|Actinomycetales	201174|Actinobacteria	C	Respiratory nitrate reductase, gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
gnl|extdb|FAM1414-i1-1.1_002274	1227261.HMPREF0043_01367	1.7e-83	264.0	COG2345@1|root,COG2345@2|Bacteria,2GW1M@201174|Actinobacteria,4D3N7@85005|Actinomycetales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR,MarR_2,ThiS
gnl|extdb|FAM1414-i1-1.1_002276	754252.PFREUD_21770	3.57e-203	563.0	COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,4DNCG@85009|Propionibacteriales	201174|Actinobacteria	H	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
gnl|extdb|FAM1414-i1-1.1_002278	754252.PFREUD_21800	4.29e-120	345.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4DQPG@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
gnl|extdb|FAM1414-i1-1.1_002279	754252.PFREUD_21810	2.54e-132	375.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4DQU7@85009|Propionibacteriales	201174|Actinobacteria	H	Probable molybdopterin binding domain	moaB	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
gnl|extdb|FAM1414-i1-1.1_002280	754252.PFREUD_21820	1.12e-104	302.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
gnl|extdb|FAM1414-i1-1.1_002281	754252.PFREUD_21830	9.13e-194	536.0	COG1794@1|root,COG1794@2|Bacteria,2ICDA@201174|Actinobacteria	201174|Actinobacteria	M	racemase activity, acting on amino acids and derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002282	754252.PFREUD_21840	2.34e-300	819.0	COG0665@1|root,COG0665@2|Bacteria,2GMR7@201174|Actinobacteria,4DPH7@85009|Propionibacteriales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_3
gnl|extdb|FAM1414-i1-1.1_002283	754252.PFREUD_21850	7.18e-86	253.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
gnl|extdb|FAM1414-i1-1.1_002284	754252.PFREUD_21860	9.38e-187	519.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DP52@85009|Propionibacteriales	201174|Actinobacteria	E	amino acid ABC transporter, ATP-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_002285	754252.PFREUD_21870	3.69e-198	550.0	COG0834@1|root,COG0834@2|Bacteria,2IPCR@201174|Actinobacteria	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
gnl|extdb|FAM1414-i1-1.1_002286	754252.PFREUD_21880	1.6e-140	398.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria	201174|Actinobacteria	E	amino acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002287	754252.PFREUD_21890	9.72e-139	393.0	COG0765@1|root,COG0765@2|Bacteria,2ISHP@201174|Actinobacteria,4DV4K@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002288	754252.PFREUD_21900	1.49e-251	690.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DPID@85009|Propionibacteriales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	adh	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
gnl|extdb|FAM1414-i1-1.1_002289	754252.PFREUD_21910	1.28e-253	696.0	COG0111@1|root,COG0111@2|Bacteria,2I3FK@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
gnl|extdb|FAM1414-i1-1.1_002290	754252.PFREUD_21920	0.0	886.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
gnl|extdb|FAM1414-i1-1.1_002291	754252.PFREUD_21930	0.0	955.0	COG2508@1|root,COG2508@2|Bacteria,2GNDH@201174|Actinobacteria	201174|Actinobacteria	QT	Regulator of polyketide synthase expression	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
gnl|extdb|FAM1414-i1-1.1_002292	754252.PFREUD_21960	0.0	1149.0	2CC7E@1|root,2Z7WG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002293	754252.PFREUD_21970	5.01e-312	853.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4DN2N@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
gnl|extdb|FAM1414-i1-1.1_002294	754252.PFREUD_21980	3.27e-150	423.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DPI9@85009|Propionibacteriales	201174|Actinobacteria	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
gnl|extdb|FAM1414-i1-1.1_002295	754252.PFREUD_21990	1.37e-222	614.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
gnl|extdb|FAM1414-i1-1.1_002296	754252.PFREUD_22020	5.1e-308	842.0	COG2270@1|root,COG2270@2|Bacteria,2GK5A@201174|Actinobacteria,4DQ23@85009|Propionibacteriales	201174|Actinobacteria	S	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_002297	754252.PFREUD_22030	1.06e-125	359.0	COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria,4DQEH@85009|Propionibacteriales	201174|Actinobacteria	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
gnl|extdb|FAM1414-i1-1.1_002298	754252.PFREUD_22040	0.0	2087.0	COG1652@1|root,COG1652@2|Bacteria,2GWK7@201174|Actinobacteria	201174|Actinobacteria	NU	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
gnl|extdb|FAM1414-i1-1.1_002299	1122994.AUFR01000011_gene2038	9.46e-44	147.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
gnl|extdb|FAM1414-i1-1.1_002300	1035308.AQYY01000002_gene277	6.74e-13	67.4	2EMTJ@1|root,33FFX@2|Bacteria	2|Bacteria	S	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
gnl|extdb|FAM1414-i1-1.1_002302	754252.PFREUD_22080	9.42e-204	565.0	COG2064@1|root,COG2064@2|Bacteria,2HZTC@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
gnl|extdb|FAM1414-i1-1.1_002303	754252.PFREUD_22090	2.22e-200	556.0	COG4965@1|root,COG4965@2|Bacteria,2GN6E@201174|Actinobacteria,4DQV5@85009|Propionibacteriales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
gnl|extdb|FAM1414-i1-1.1_002305	754252.PFREUD_22110	6.17e-238	655.0	COG1192@1|root,COG1192@2|Bacteria,2I57A@201174|Actinobacteria,4DS3J@85009|Propionibacteriales	201174|Actinobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002306	754252.PFREUD_22120	1.86e-110	320.0	COG1261@1|root,COG1261@2|Bacteria,2IR93@201174|Actinobacteria,4DW2A@85009|Propionibacteriales	201174|Actinobacteria	NO	SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	SAF
gnl|extdb|FAM1414-i1-1.1_002307	1074488.AGBX01000007_gene1502	4.91e-19	81.3	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4FCZ7@85020|Dermabacteraceae	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_002197	754252.PFREUD_20780	0.0	1420.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DN8M@85009|Propionibacteriales	201174|Actinobacteria	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
gnl|extdb|FAM1414-i1-1.1_002199	754252.PFREUD_20800	7.08e-91	270.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4DRND@85009|Propionibacteriales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
gnl|extdb|FAM1414-i1-1.1_002223	1299327.I546_1626	1.45e-29	108.0	2DSMY@1|root,33GQS@2|Bacteria,2GS9Y@201174|Actinobacteria,23B40@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
gnl|extdb|FAM1414-i1-1.1_002240	754252.PFREUD_21470	2.46e-239	661.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4DNKD@85009|Propionibacteriales	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
gnl|extdb|FAM1414-i1-1.1_002251	754252.PFREUD_21590	4.36e-169	474.0	COG4208@1|root,COG4208@2|Bacteria,2GMTK@201174|Actinobacteria,4DNNA@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002256	754252.PFREUD_21640	1.79e-244	671.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4DPJX@85009|Propionibacteriales	201174|Actinobacteria	EH	Sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
gnl|extdb|FAM1414-i1-1.1_002263	1122994.AUFR01000060_gene620	2.2e-26	109.0	COG3842@1|root,COG4149@1|root,COG3842@2|Bacteria,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4DPG9@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
gnl|extdb|FAM1414-i1-1.1_002268	1120942.AUBM01000001_gene1299	4.53e-44	156.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4D32B@85005|Actinomycetales	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
gnl|extdb|FAM1414-i1-1.1_002269	1122994.AUFR01000011_gene1980	6.16e-249	690.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria	201174|Actinobacteria	P	Major Facilitator	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_002272	754252.PFREUD_21730	2.41e-135	389.0	COG2180@1|root,COG2180@2|Bacteria,2IAQV@201174|Actinobacteria,4DRDB@85009|Propionibacteriales	201174|Actinobacteria	C	Nitrate reductase delta subunit	narJ	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
gnl|extdb|FAM1414-i1-1.1_002275	754252.PFREUD_21760	1.23e-91	268.0	COG0314@1|root,COG0314@2|Bacteria,2IQ9F@201174|Actinobacteria,4DR9R@85009|Propionibacteriales	201174|Actinobacteria	H	MoaE protein	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
gnl|extdb|FAM1414-i1-1.1_002277	754252.PFREUD_21790	0.0	900.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria	201174|Actinobacteria	H	Molybdenum cofactor synthesis domain protein	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
gnl|extdb|FAM1414-i1-1.1_002304	754252.PFREUD_22100	0.0	932.0	COG0630@1|root,COG0630@2|Bacteria,2I3XU@201174|Actinobacteria,4DNAT@85009|Propionibacteriales	201174|Actinobacteria	NU	Type II/IV secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
gnl|extdb|FAM1414-i1-1.1_002310	754252.PFREUD_23840	3.66e-292	798.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria	201174|Actinobacteria	P	Chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
gnl|extdb|FAM1414-i1-1.1_002311	1206741.BAFX01000010_gene6803	0.000131	47.8	2ETEY@1|root,33KYV@2|Bacteria,2GWJV@201174|Actinobacteria,4G4R8@85025|Nocardiaceae	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
gnl|extdb|FAM1414-i1-1.1_002312	754252.PFREUD_23820	0.0	1182.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DQX3@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
gnl|extdb|FAM1414-i1-1.1_002313	754252.PFREUD_23810	6.36e-229	629.0	COG2837@1|root,COG2837@2|Bacteria,2GMNJ@201174|Actinobacteria	201174|Actinobacteria	P	peroxidase	yfeX	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
gnl|extdb|FAM1414-i1-1.1_002314	754252.PFREUD_23800	0.0	989.0	COG0753@1|root,COG0753@2|Bacteria,2GITN@201174|Actinobacteria,4DP8F@85009|Propionibacteriales	201174|Actinobacteria	P	Serves to protect cells from the toxic effects of hydrogen peroxide	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
gnl|extdb|FAM1414-i1-1.1_002315	754252.PFREUD_23780	0.0	1133.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DWKQ@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
gnl|extdb|FAM1414-i1-1.1_002316	754252.PFREUD_23770	1.29e-233	643.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
gnl|extdb|FAM1414-i1-1.1_002317	754252.PFREUD_23760	0.0	1231.0	COG2233@1|root,COG3195@1|root,COG2233@2|Bacteria,COG3195@2|Bacteria,2GMH6@201174|Actinobacteria,4DN54@85009|Propionibacteriales	201174|Actinobacteria	F	Permease family	pbuX	-	-	-	-	-	-	-	-	-	-	-	OHCU_decarbox,Xan_ur_permease
gnl|extdb|FAM1414-i1-1.1_002319	883069.HMPREF9238_01206	5.43e-05	50.1	2ASGE@1|root,31HWJ@2|Bacteria,2HMEQ@201174|Actinobacteria,4D6VV@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002322	754252.PFREUD_23720	5.1e-204	564.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria	201174|Actinobacteria	K	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
gnl|extdb|FAM1414-i1-1.1_002323	754252.PFREUD_23710	2.21e-295	805.0	COG2124@1|root,COG2124@2|Bacteria,2IJFZ@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
gnl|extdb|FAM1414-i1-1.1_002324	936140.AEOT01000010_gene487	6.81e-06	46.6	29QT0@1|root,30BSV@2|Bacteria,1U8KV@1239|Firmicutes,4IIIW@91061|Bacilli,3FB3C@33958|Lactobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002325	754252.PFREUD_23690	5.15e-174	493.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria	201174|Actinobacteria	S	Low temperature requirement	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
gnl|extdb|FAM1414-i1-1.1_002327	754252.PFREUD_23650	6.91e-101	291.0	2CQNK@1|root,32SMG@2|Bacteria,2IIJ7@201174|Actinobacteria	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
gnl|extdb|FAM1414-i1-1.1_002328	754252.PFREUD_23640	0.0	1293.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4DMYZ@85009|Propionibacteriales	201174|Actinobacteria	M	Transglycosylase	pbp5	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
gnl|extdb|FAM1414-i1-1.1_002329	754252.PFREUD_23630	0.0	1056.0	COG5650@1|root,COG5650@2|Bacteria,2GJYA@201174|Actinobacteria,4DPN0@85009|Propionibacteriales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
gnl|extdb|FAM1414-i1-1.1_002330	754252.PFREUD_23620	4.12e-274	750.0	COG5542@1|root,COG5542@2|Bacteria,2HZNP@201174|Actinobacteria,4DTDM@85009|Propionibacteriales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
gnl|extdb|FAM1414-i1-1.1_002332	754252.PFREUD_23600	5.19e-293	799.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4DPPZ@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
gnl|extdb|FAM1414-i1-1.1_002333	754252.PFREUD_23590	4.36e-149	419.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria,4DQTX@85009|Propionibacteriales	201174|Actinobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
gnl|extdb|FAM1414-i1-1.1_002334	754252.PFREUD_23580	9.93e-285	780.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,4DTNQ@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_002335	754252.PFREUD_23530	1.04e-163	459.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
gnl|extdb|FAM1414-i1-1.1_002336	754252.PFREUD_23520	4.16e-85	251.0	COG0607@1|root,COG0607@2|Bacteria,2IH0R@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
gnl|extdb|FAM1414-i1-1.1_002337	754252.PFREUD_23510	7.2e-166	463.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4DP69@85009|Propionibacteriales	201174|Actinobacteria	S	Chlorite dismutase	cld	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
gnl|extdb|FAM1414-i1-1.1_002338	754252.PFREUD_23500	5.41e-84	247.0	COG0221@1|root,COG0221@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002341	754252.PFREUD_23460	4.5e-114	329.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4DQ95@85009|Propionibacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
gnl|extdb|FAM1414-i1-1.1_002342	754252.PFREUD_23450	2.88e-47	151.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4DRVS@85009|Propionibacteriales	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
gnl|extdb|FAM1414-i1-1.1_002343	754252.PFREUD_23440	3.2e-100	291.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4DQYG@85009|Propionibacteriales	201174|Actinobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
gnl|extdb|FAM1414-i1-1.1_002344	754252.PFREUD_23430	0.0	974.0	COG0477@1|root,COG2814@2|Bacteria,2H32P@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_002345	754252.PFREUD_23420	0.0	931.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	ugpB	-	-	ko:K02027,ko:K05813	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	SBP_bac_8
gnl|extdb|FAM1414-i1-1.1_002346	754252.PFREUD_23410	2.57e-225	622.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter (Permease)	ugpE	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002347	754252.PFREUD_23400	7.36e-224	619.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4DQWD@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002348	754252.PFREUD_23380	2.3e-24	100.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
gnl|extdb|FAM1414-i1-1.1_002349	1306174.JODP01000016_gene7165	2.58e-104	325.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
gnl|extdb|FAM1414-i1-1.1_002350	754252.PFREUD_23350	2.05e-60	190.0	COG3797@1|root,COG3797@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
gnl|extdb|FAM1414-i1-1.1_002352	1121363.KB902227_gene2520	6.58e-07	48.9	2AYAG@1|root,31QD0@2|Bacteria,2HSG6@201174|Actinobacteria,22QXD@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002353	1121363.KB902227_gene2521	1.97e-33	120.0	COG3654@1|root,COG3654@2|Bacteria,2HWRI@201174|Actinobacteria,22PTF@1653|Corynebacteriaceae	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
gnl|extdb|FAM1414-i1-1.1_002354	754252.PFREUD_23330	1.78e-283	775.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4DN5T@85009|Propionibacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.1,2.6.1.17,2.6.1.2,2.6.1.66	ko:K00812,ko:K10907,ko:K14260,ko:K14267	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R04475,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
gnl|extdb|FAM1414-i1-1.1_002355	76636.JOEC01000001_gene494	6.67e-129	375.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4FKS0@85023|Microbacteriaceae	201174|Actinobacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
gnl|extdb|FAM1414-i1-1.1_002356	46429.BV95_02825	0.000203	45.4	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria,2K29S@204457|Sphingomonadales	204457|Sphingomonadales	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
gnl|extdb|FAM1414-i1-1.1_002357	754252.PFREUD_23320	1.71e-116	338.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter (Permease)	proZ	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002358	754252.PFREUD_23310	1.3e-117	340.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,4DQQZ@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002359	754252.PFREUD_23300	8.74e-170	479.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4DPZM@85009|Propionibacteriales	201174|Actinobacteria	E	ABC transporter	proV	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iNJ661.Rv3758c	ABC_tran
gnl|extdb|FAM1414-i1-1.1_002361	754252.PFREUD_23280	4e-160	452.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4DS0X@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
gnl|extdb|FAM1414-i1-1.1_002362	754252.PFREUD_00530	3.89e-172	502.0	COG1807@1|root,COG1807@2|Bacteria,2I48D@201174|Actinobacteria,4DWG9@85009|Propionibacteriales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
gnl|extdb|FAM1414-i1-1.1_002363	754252.PFREUD_23250	2.87e-214	612.0	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
gnl|extdb|FAM1414-i1-1.1_002364	292.DM42_4409	1.08e-82	258.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,2VJIS@28216|Betaproteobacteria,1K296@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
gnl|extdb|FAM1414-i1-1.1_002365	754252.PFREUD_23240	0.0	911.0	COG0531@1|root,COG0531@2|Bacteria,2HMMA@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
gnl|extdb|FAM1414-i1-1.1_002366	754252.PFREUD_23230	0.0	975.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4DPUT@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	gadB	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
gnl|extdb|FAM1414-i1-1.1_002367	754252.PFREUD_23220	2.97e-206	569.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria,4DQ8V@85009|Propionibacteriales	201174|Actinobacteria	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
gnl|extdb|FAM1414-i1-1.1_002368	754252.PFREUD_23210	7.52e-240	660.0	COG1609@1|root,COG1609@2|Bacteria,2GMUU@201174|Actinobacteria,4DNP6@85009|Propionibacteriales	201174|Actinobacteria	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
gnl|extdb|FAM1414-i1-1.1_002369	754252.PFREUD_23200	4.35e-277	758.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4DPFS@85009|Propionibacteriales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
gnl|extdb|FAM1414-i1-1.1_002370	754252.PFREUD_23190	8.68e-257	702.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria,4DNDR@85009|Propionibacteriales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
gnl|extdb|FAM1414-i1-1.1_002371	754252.PFREUD_23180	4.13e-180	501.0	COG2375@1|root,COG2375@2|Bacteria,2GP41@201174|Actinobacteria	201174|Actinobacteria	P	siderophore-interacting protein	-	-	-	ko:K14698	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.21.2	-	-	FAD_binding_9,SIP
gnl|extdb|FAM1414-i1-1.1_002372	754252.PFREUD_23170	5.54e-303	829.0	COG2271@1|root,COG2271@2|Bacteria,2I5AK@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_002374	754252.PFREUD_23150	7.49e-236	647.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
gnl|extdb|FAM1414-i1-1.1_002376	754252.PFREUD_23140	1.4e-238	657.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
gnl|extdb|FAM1414-i1-1.1_002377	754252.PFREUD_23130	2.66e-217	598.0	COG1082@1|root,COG1082@2|Bacteria,2GMU1@201174|Actinobacteria,4DVPQ@85009|Propionibacteriales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	iolH	-	-	ko:K06605	-	-	-	-	ko00000	-	-	-	AP_endonuc_2
gnl|extdb|FAM1414-i1-1.1_002378	1171373.PACID_34140	1.19e-175	497.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DT8B@85009|Propionibacteriales	201174|Actinobacteria	S	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
gnl|extdb|FAM1414-i1-1.1_002379	1122997.AUDD01000015_gene1612	5.5e-207	574.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria	201174|Actinobacteria	G	dehydratase	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
gnl|extdb|FAM1414-i1-1.1_002380	1122997.AUDD01000004_gene1329	2.83e-78	248.0	COG0730@1|root,COG0730@2|Bacteria,2GK5W@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
gnl|extdb|FAM1414-i1-1.1_002381	1133569.AHYZ01000122_gene8	1.27e-93	297.0	COG0477@1|root,COG2814@2|Bacteria,1VU5Q@1239|Firmicutes,4HUUP@91061|Bacilli,3F3JN@33958|Lactobacillaceae	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	ko:K18934	-	-	-	-	ko00000,ko02000	2.A.1.3.39	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_002382	1184609.KILIM_022_00040	2.37e-13	67.4	2EBXP@1|root,335X1@2|Bacteria,2I70R@201174|Actinobacteria	201174|Actinobacteria	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
gnl|extdb|FAM1414-i1-1.1_002383	411473.RUMCAL_00506	4.15e-208	606.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,3WNN8@541000|Ruminococcaceae	186801|Clostridia	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
gnl|extdb|FAM1414-i1-1.1_002384	269800.Tfu_1353	9.26e-194	556.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4EHQR@85012|Streptosporangiales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
gnl|extdb|FAM1414-i1-1.1_002385	882083.SacmaDRAFT_2713	4.83e-70	221.0	COG1116@1|root,COG1116@2|Bacteria,2GM73@201174|Actinobacteria,4E9GC@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_002386	1463855.JOHV01000046_gene229	1e-45	162.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002387	1312959.KI914657_gene3528	1.52e-46	166.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria,1W8V5@1268|Micrococcaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_002388	1122611.KB903941_gene2139	9.96e-31	125.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria,4EG1E@85012|Streptosporangiales	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
gnl|extdb|FAM1414-i1-1.1_002389	754252.PFREUD_00750	7.85e-283	776.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	aslB	GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
gnl|extdb|FAM1414-i1-1.1_002390	754252.PFREUD_00760	0.0	1032.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
gnl|extdb|FAM1414-i1-1.1_002391	754252.PFREUD_00770	1.16e-240	662.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
gnl|extdb|FAM1414-i1-1.1_002392	754252.PFREUD_00780	8.95e-176	491.0	COG1349@1|root,COG1349@2|Bacteria,2I8G0@201174|Actinobacteria	201174|Actinobacteria	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
gnl|extdb|FAM1414-i1-1.1_002393	754252.PFREUD_00790	2.97e-243	667.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria,4DPY4@85009|Propionibacteriales	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002396	754252.PFREUD_00820	1.44e-163	457.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DP6U@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
gnl|extdb|FAM1414-i1-1.1_002397	754252.PFREUD_00830	4.06e-195	543.0	COG4242@1|root,COG4242@2|Bacteria,2IG1C@201174|Actinobacteria,4DSB5@85009|Propionibacteriales	201174|Actinobacteria	PQ	Belongs to the peptidase S51 family	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
gnl|extdb|FAM1414-i1-1.1_002399	754252.PFREUD_00850	1.77e-81	241.0	COG1950@1|root,COG1950@2|Bacteria	2|Bacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
gnl|extdb|FAM1414-i1-1.1_002400	754252.PFREUD_00860	7e-243	667.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4DPPU@85009|Propionibacteriales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
gnl|extdb|FAM1414-i1-1.1_002401	754252.PFREUD_00870	4.06e-145	408.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4DQD9@85009|Propionibacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
gnl|extdb|FAM1414-i1-1.1_002402	754252.PFREUD_00880	1.2e-191	531.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4DPW6@85009|Propionibacteriales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
gnl|extdb|FAM1414-i1-1.1_002403	754252.PFREUD_24270	0.0	881.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_002320	754252.PFREUD_23740	0.0	1131.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4DNRU@85009|Propionibacteriales	201174|Actinobacteria	G	SMART alpha amylase, catalytic sub domain	aglA	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
gnl|extdb|FAM1414-i1-1.1_002331	754252.PFREUD_23610	0.0	877.0	COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria,4DT3W@85009|Propionibacteriales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	nplT	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
gnl|extdb|FAM1414-i1-1.1_002340	754252.PFREUD_23470	1.63e-62	191.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4DRPR@85009|Propionibacteriales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
gnl|extdb|FAM1414-i1-1.1_002373	754252.PFREUD_23160	3.75e-163	457.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4DQNY@85009|Propionibacteriales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
gnl|extdb|FAM1414-i1-1.1_002375	1479623.JHEL01000009_gene1730	2.31e-25	96.3	2D5VR@1|root,32TJX@2|Bacteria,2I34C@201174|Actinobacteria,4FTQQ@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002395	754252.PFREUD_00810	3.33e-315	860.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4DP7S@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	mprB	GO:0000160,GO:0003674,GO:0003824,GO:0004721,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0040007,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
gnl|extdb|FAM1414-i1-1.1_002398	754252.PFREUD_00840	1.29e-94	276.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4DR9C@85009|Propionibacteriales	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
gnl|extdb|FAM1414-i1-1.1_002404	754252.PFREUD_17940	1.14e-100	291.0	COG3118@1|root,COG3118@2|Bacteria,2IHQV@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
gnl|extdb|FAM1414-i1-1.1_002407	318424.EU78_05920	9.5e-10	65.9	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,2343K@1762|Mycobacteriaceae	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
gnl|extdb|FAM1414-i1-1.1_002408	754252.PFREUD_17900	5.38e-204	566.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DNMP@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
gnl|extdb|FAM1414-i1-1.1_002409	754252.PFREUD_17890	1.23e-154	434.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4DQ2F@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
gnl|extdb|FAM1414-i1-1.1_002410	666684.AfiDRAFT_3530	1.72e-08	59.3	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,2U93B@28211|Alphaproteobacteria,3JZ0D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
gnl|extdb|FAM1414-i1-1.1_002412	754252.PFREUD_17860	1.61e-194	541.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	degP	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
gnl|extdb|FAM1414-i1-1.1_002414	754252.PFREUD_17830	8.88e-126	358.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
gnl|extdb|FAM1414-i1-1.1_002415	754252.PFREUD_17820	5.86e-237	654.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4DNFB@85009|Propionibacteriales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
gnl|extdb|FAM1414-i1-1.1_002416	754252.PFREUD_17810	1.98e-91	268.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	racA	-	-	ko:K11686,ko:K13640,ko:K18997	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	DUF1836,MerR_1,MerR_2
gnl|extdb|FAM1414-i1-1.1_002417	1120947.ATUX01000005_gene1507	2.72e-17	80.1	COG2169@1|root,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	rhaS	-	3.2.2.21	ko:K02854,ko:K02855,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlkA_N,AraC_binding,Endonuclea_NS_2,HTH_18
gnl|extdb|FAM1414-i1-1.1_002419	754252.PFREUD_17770	4.23e-123	352.0	28PR5@1|root,2ZCD3@2|Bacteria,2GTWC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002420	754252.PFREUD_17760	1.04e-268	737.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4DVA2@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
gnl|extdb|FAM1414-i1-1.1_002421	754252.PFREUD_17750	3.2e-136	387.0	COG2197@1|root,COG2197@2|Bacteria,2HF6M@201174|Actinobacteria,4DUWR@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
gnl|extdb|FAM1414-i1-1.1_002422	754252.PFREUD_17740	2.27e-174	487.0	2A730@1|root,30VYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002423	754252.PFREUD_17710	1.11e-160	449.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
gnl|extdb|FAM1414-i1-1.1_002424	754252.PFREUD_17700	2.45e-86	253.0	COG0346@1|root,COG0346@2|Bacteria,2IHNJ@201174|Actinobacteria,4DVAQ@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
gnl|extdb|FAM1414-i1-1.1_002425	754252.PFREUD_17690	8.95e-95	276.0	COG1846@1|root,COG1846@2|Bacteria,2IFEY@201174|Actinobacteria,4DVR8@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
gnl|extdb|FAM1414-i1-1.1_002426	754252.PFREUD_17680	7.86e-67	204.0	COG0640@1|root,COG0640@2|Bacteria,2GSCM@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
gnl|extdb|FAM1414-i1-1.1_002428	754252.PFREUD_17660	0.0	924.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DPQY@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	proP	-	-	ko:K03761,ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.2,2.A.1.6.4	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_002429	754252.PFREUD_17650	1.85e-131	374.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_002432	754252.PFREUD_17600	7.44e-116	331.0	COG0454@1|root,COG0456@2|Bacteria,2GNNG@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
gnl|extdb|FAM1414-i1-1.1_002435	754252.PFREUD_17570	4.86e-124	353.0	COG0589@1|root,COG0589@2|Bacteria,2GUPR@201174|Actinobacteria	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
gnl|extdb|FAM1414-i1-1.1_002436	754252.PFREUD_17560	1.25e-282	773.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4DQ3A@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
gnl|extdb|FAM1414-i1-1.1_002437	754252.PFREUD_17540	2.95e-123	351.0	COG4297@1|root,COG4297@2|Bacteria,2H7KC@201174|Actinobacteria	201174|Actinobacteria	S	protein containing double-stranded beta helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
gnl|extdb|FAM1414-i1-1.1_002438	754252.PFREUD_17530	0.0	1001.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4DP9E@85009|Propionibacteriales	201174|Actinobacteria	F	Permease family	rutG	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
gnl|extdb|FAM1414-i1-1.1_002439	754252.PFREUD_17520	2.24e-240	662.0	COG1434@1|root,COG1434@2|Bacteria,2GMGZ@201174|Actinobacteria	201174|Actinobacteria	V	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
gnl|extdb|FAM1414-i1-1.1_002441	754252.PFREUD_17500	0.0	1543.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
gnl|extdb|FAM1414-i1-1.1_002442	754252.PFREUD_17490	1.91e-203	563.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4DN3D@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
gnl|extdb|FAM1414-i1-1.1_002444	754252.PFREUD_17470	2.11e-196	546.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4DN5S@85009|Propionibacteriales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
gnl|extdb|FAM1414-i1-1.1_002447	754252.PFREUD_17440	1.74e-250	687.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
gnl|extdb|FAM1414-i1-1.1_002449	754252.PFREUD_17410	0.0	895.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4DNA1@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
gnl|extdb|FAM1414-i1-1.1_002450	754252.PFREUD_17400	6.2e-240	659.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4DP73@85009|Propionibacteriales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
gnl|extdb|FAM1414-i1-1.1_002451	754252.PFREUD_17390	3.42e-131	375.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4DQEY@85009|Propionibacteriales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
gnl|extdb|FAM1414-i1-1.1_002452	754252.PFREUD_17370	1.03e-139	394.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4DPFB@85009|Propionibacteriales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
gnl|extdb|FAM1414-i1-1.1_002453	754252.PFREUD_17360	8.24e-71	214.0	COG1610@1|root,COG1610@2|Bacteria	2|Bacteria	S	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
gnl|extdb|FAM1414-i1-1.1_002454	754252.PFREUD_17350	0.0	2361.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4DNWF@85009|Propionibacteriales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
gnl|extdb|FAM1414-i1-1.1_002455	754252.PFREUD_17340	8.68e-118	337.0	COG0760@1|root,COG0760@2|Bacteria,2ICFD@201174|Actinobacteria	201174|Actinobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002456	754252.PFREUD_17330	1.5e-152	429.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4DV8P@85009|Propionibacteriales	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
gnl|extdb|FAM1414-i1-1.1_002457	754252.PFREUD_17320	2.26e-303	828.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4DPWS@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
gnl|extdb|FAM1414-i1-1.1_002458	754252.PFREUD_17310	4.21e-92	275.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4DS5K@85009|Propionibacteriales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
gnl|extdb|FAM1414-i1-1.1_002459	754252.PFREUD_17300	1.07e-124	354.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4DQUA@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
gnl|extdb|FAM1414-i1-1.1_002460	754252.PFREUD_17290	9.98e-219	604.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4DQ85@85009|Propionibacteriales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
gnl|extdb|FAM1414-i1-1.1_002462	1184609.KILIM_019_00150	5.7e-59	191.0	COG1309@1|root,COG1309@2|Bacteria,2GNBI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
gnl|extdb|FAM1414-i1-1.1_002463	857290.HMPREF9156_01208	9.73e-72	227.0	COG0842@1|root,COG0842@2|Bacteria,2IB08@201174|Actinobacteria,4D0DK@85004|Bifidobacteriales	201174|Actinobacteria	U	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
gnl|extdb|FAM1414-i1-1.1_002464	857290.HMPREF9156_01209	1.98e-87	271.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CYUQ@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_002465	754252.PFREUD_17270	5.25e-316	863.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DPE6@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_002466	754252.PFREUD_17260	2.8e-130	371.0	COG1309@1|root,COG1309@2|Bacteria,2GNND@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_002467	754252.PFREUD_17250	7.95e-310	843.0	COG0148@1|root,COG0148@2|Bacteria,2IA5M@201174|Actinobacteria,4DWPR@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno2	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
gnl|extdb|FAM1414-i1-1.1_002468	754252.PFREUD_17240	0.0	891.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4DPTX@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
gnl|extdb|FAM1414-i1-1.1_002469	754252.PFREUD_17230	2.12e-178	497.0	COG0702@1|root,COG0702@2|Bacteria,2ID6I@201174|Actinobacteria	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
gnl|extdb|FAM1414-i1-1.1_002470	754252.PFREUD_17220	9.87e-189	523.0	COG0500@1|root,COG0500@2|Bacteria,2GM5T@201174|Actinobacteria,4DQPT@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
gnl|extdb|FAM1414-i1-1.1_002471	754252.PFREUD_17210	8.2e-178	497.0	COG4760@1|root,COG4760@2|Bacteria,2GNCK@201174|Actinobacteria,4DQBD@85009|Propionibacteriales	201174|Actinobacteria	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
gnl|extdb|FAM1414-i1-1.1_002472	754252.PFREUD_17200	3.04e-171	477.0	COG1051@1|root,COG1051@2|Bacteria,2GPP2@201174|Actinobacteria,4DQE2@85009|Propionibacteriales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_002473	754252.PFREUD_17190	1.94e-214	593.0	299UX@1|root,2ZWWZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002474	754252.PFREUD_17180	1.11e-155	436.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4DQWP@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
gnl|extdb|FAM1414-i1-1.1_002475	754252.PFREUD_17160	4.06e-93	271.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
gnl|extdb|FAM1414-i1-1.1_002477	754252.PFREUD_17140	7.29e-126	357.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4DR3V@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
gnl|extdb|FAM1414-i1-1.1_002478	754252.PFREUD_17130	2.53e-146	412.0	COG1011@1|root,COG1011@2|Bacteria,2IHVB@201174|Actinobacteria	201174|Actinobacteria	S	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
gnl|extdb|FAM1414-i1-1.1_002479	754252.PFREUD_17120	7.16e-147	414.0	COG3467@1|root,COG3467@2|Bacteria,2GJ76@201174|Actinobacteria,4DVES@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
gnl|extdb|FAM1414-i1-1.1_002482	754252.PFREUD_17090	4.68e-168	469.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4DT7D@85009|Propionibacteriales	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
gnl|extdb|FAM1414-i1-1.1_002483	754252.PFREUD_17080	1.42e-307	842.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4DNK8@85009|Propionibacteriales	201174|Actinobacteria	S	AI-2E family transporter	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
gnl|extdb|FAM1414-i1-1.1_002484	754252.PFREUD_17070	1.27e-222	614.0	2B5R0@1|root,31YKI@2|Bacteria,2IPMA@201174|Actinobacteria,4DR93@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002485	754252.PFREUD_17060	2.79e-88	260.0	COG2259@1|root,COG2259@2|Bacteria,2GUAH@201174|Actinobacteria	201174|Actinobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
gnl|extdb|FAM1414-i1-1.1_002486	754252.PFREUD_17050	2.17e-113	325.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4DQI3@85009|Propionibacteriales	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
gnl|extdb|FAM1414-i1-1.1_002487	754252.PFREUD_17040	4.69e-237	650.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4DP8N@85009|Propionibacteriales	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
gnl|extdb|FAM1414-i1-1.1_002488	754252.PFREUD_17030	0.0	1795.0	COG1331@1|root,COG4405@1|root,COG1331@2|Bacteria,COG4405@2|Bacteria,2IE03@201174|Actinobacteria,4DWN1@85009|Propionibacteriales	201174|Actinobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
gnl|extdb|FAM1414-i1-1.1_002489	754252.PFREUD_17020	2.73e-123	351.0	COG4405@1|root,COG4405@2|Bacteria	2|Bacteria	I	Protein conserved in bacteria	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	ASCH
gnl|extdb|FAM1414-i1-1.1_002490	754252.PFREUD_17010	4.03e-198	548.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4DPJB@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS1	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
gnl|extdb|FAM1414-i1-1.1_002492	754252.PFREUD_16990	3.76e-48	154.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
gnl|extdb|FAM1414-i1-1.1_002493	754252.PFREUD_16980	1.02e-311	851.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4DNJ0@85009|Propionibacteriales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
gnl|extdb|FAM1414-i1-1.1_002494	754252.PFREUD_16970	2.22e-232	640.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4DP0N@85009|Propionibacteriales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
gnl|extdb|FAM1414-i1-1.1_002495	754252.PFREUD_16950	6.49e-304	831.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4DN8P@85009|Propionibacteriales	201174|Actinobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
gnl|extdb|FAM1414-i1-1.1_002496	754252.PFREUD_16940	8.27e-309	841.0	COG1362@1|root,COG1362@2|Bacteria,2GKW4@201174|Actinobacteria,4DPTA@85009|Propionibacteriales	201174|Actinobacteria	E	Aminopeptidase I zinc metalloprotease (M18)	apeB	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
gnl|extdb|FAM1414-i1-1.1_002497	754252.PFREUD_16930	1.6e-252	693.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4DP3C@85009|Propionibacteriales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
gnl|extdb|FAM1414-i1-1.1_002498	223184.AS25_13660	1.31e-62	195.0	COG3293@1|root,COG3293@2|Bacteria,2IKID@201174|Actinobacteria,1W9RI@1268|Micrococcaceae	201174|Actinobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DUF4096
gnl|extdb|FAM1414-i1-1.1_002499	223184.AS25_13655	0.0	1583.0	COG0457@1|root,COG1672@1|root,COG4995@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CHAT,NB-ARC,TIR_2,TPR_12,TPR_8
gnl|extdb|FAM1414-i1-1.1_002500	223184.AS25_13660	1.41e-110	323.0	COG3293@1|root,COG3293@2|Bacteria,2IKID@201174|Actinobacteria,1W9RI@1268|Micrococcaceae	201174|Actinobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DUF4096
gnl|extdb|FAM1414-i1-1.1_002501	223184.AS25_08350	8.6e-32	112.0	COG1396@1|root,COG1396@2|Bacteria,2HWH4@201174|Actinobacteria,1WA91@1268|Micrococcaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
gnl|extdb|FAM1414-i1-1.1_002502	321955.AAGP01000001_gene3246	4.98e-13	68.2	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4F98Z@85019|Brevibacteriaceae	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
gnl|extdb|FAM1414-i1-1.1_002503	1122175.ATXU01000002_gene1329	0.0	994.0	COG0286@1|root,COG0286@2|Bacteria,2GKAQ@201174|Actinobacteria,4FKWC@85023|Microbacteriaceae	201174|Actinobacteria	V	N-6 DNA Methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
gnl|extdb|FAM1414-i1-1.1_002504	1123013.AUIC01000004_gene1927	6.6e-128	381.0	COG0732@1|root,COG0732@2|Bacteria,2IAIR@201174|Actinobacteria,4FSB8@85023|Microbacteriaceae	201174|Actinobacteria	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
gnl|extdb|FAM1414-i1-1.1_002505	321955.AAGP01000001_gene3242	0.0	1784.0	COG0610@1|root,COG0610@2|Bacteria,2HI69@201174|Actinobacteria	201174|Actinobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoR124_C,HSDR_N,ResIII
gnl|extdb|FAM1414-i1-1.1_002406	754252.PFREUD_17920	0.0	1534.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4DN44@85009|Propionibacteriales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
gnl|extdb|FAM1414-i1-1.1_002413	754252.PFREUD_17840	0.0	1161.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4DP1V@85009|Propionibacteriales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
gnl|extdb|FAM1414-i1-1.1_002418	1089455.MOPEL_021_00660	3.58e-55	175.0	2EJS5@1|root,33DGX@2|Bacteria,2GY44@201174|Actinobacteria,4F7DW@85018|Dermatophilaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_002427	754252.PFREUD_17670	0.0	895.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_002430	754252.PFREUD_17620	6.9e-268	739.0	COG0477@1|root,COG0477@2|Bacteria,2GKQH@201174|Actinobacteria,4DWWP@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_002431	754252.PFREUD_17610	0.0	895.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4DP86@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
gnl|extdb|FAM1414-i1-1.1_002433	754252.PFREUD_17590	1.54e-79	236.0	COG0239@1|root,COG0239@2|Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
gnl|extdb|FAM1414-i1-1.1_002434	754252.PFREUD_17580	1.72e-93	273.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,4DSBC@85009|Propionibacteriales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB2	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
gnl|extdb|FAM1414-i1-1.1_002440	754252.PFREUD_17510	0.0	1024.0	COG1928@1|root,COG1928@2|Bacteria,2I2H1@201174|Actinobacteria,4DP3Z@85009|Propionibacteriales	201174|Actinobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	pmt	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
gnl|extdb|FAM1414-i1-1.1_002443	754252.PFREUD_17480	1.92e-224	619.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4DPJ5@85009|Propionibacteriales	201174|Actinobacteria	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
gnl|extdb|FAM1414-i1-1.1_002445	754252.PFREUD_17460	1.07e-209	581.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4DPS0@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
gnl|extdb|FAM1414-i1-1.1_002446	754252.PFREUD_17450	3.91e-169	474.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_002481	754252.PFREUD_17100	3.83e-154	432.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4DQ8G@85009|Propionibacteriales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
gnl|extdb|FAM1414-i1-1.1_002491	754252.PFREUD_17000	3.42e-178	496.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4DQ8R@85009|Propionibacteriales	201174|Actinobacteria	S	Haemolysin-III related	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
gnl|extdb|FAM1414-i1-1.1_000469	1074488.AGBX01000007_gene1502	4.91e-19	81.3	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4FCZ7@85020|Dermabacteraceae	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_000470	754252.PFREUD_08110	1.72e-153	430.0	COG2761@1|root,COG2761@2|Bacteria,2GJNX@201174|Actinobacteria,4DX18@85009|Propionibacteriales	201174|Actinobacteria	Q	DSBA oxidoreductase	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DSBA
gnl|extdb|FAM1414-i1-1.1_000471	754252.PFREUD_08120	9.05e-188	521.0	2CNM1@1|root,32SHB@2|Bacteria,2GKWT@201174|Actinobacteria,4DR39@85009|Propionibacteriales	201174|Actinobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
gnl|extdb|FAM1414-i1-1.1_000472	754252.PFREUD_08130	0.0	1444.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4DNKM@85009|Propionibacteriales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
gnl|extdb|FAM1414-i1-1.1_000478	754252.PFREUD_08210	0.0	876.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4DP8U@85009|Propionibacteriales	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
gnl|extdb|FAM1414-i1-1.1_000479	754252.PFREUD_08220	7.01e-268	735.0	COG0628@1|root,COG0628@2|Bacteria,2GM01@201174|Actinobacteria,4DT6M@85009|Propionibacteriales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
gnl|extdb|FAM1414-i1-1.1_000480	754252.PFREUD_08230	1.19e-285	782.0	COG0628@1|root,COG0628@2|Bacteria,2GM01@201174|Actinobacteria	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
gnl|extdb|FAM1414-i1-1.1_000483	754252.PFREUD_08260	7.01e-305	831.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4DP0T@85009|Propionibacteriales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
gnl|extdb|FAM1414-i1-1.1_000484	754252.PFREUD_08280	0.0	960.0	COG0498@1|root,COG0498@2|Bacteria,2GIRY@201174|Actinobacteria	201174|Actinobacteria	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
gnl|extdb|FAM1414-i1-1.1_000485	754252.PFREUD_08290	1.58e-261	717.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DPJ3@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
gnl|extdb|FAM1414-i1-1.1_000486	754252.PFREUD_08300	2.93e-181	504.0	COG1011@1|root,COG1011@2|Bacteria,2GNSS@201174|Actinobacteria	201174|Actinobacteria	S	hydrolase	-	-	3.1.3.102,3.1.3.104	ko:K07025,ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
gnl|extdb|FAM1414-i1-1.1_000487	754252.PFREUD_08310	0.0	1788.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4DNR2@85009|Propionibacteriales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
gnl|extdb|FAM1414-i1-1.1_000488	754252.PFREUD_08320	1.02e-152	433.0	COG1651@1|root,COG1651@2|Bacteria,2GKH8@201174|Actinobacteria	201174|Actinobacteria	O	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
gnl|extdb|FAM1414-i1-1.1_000489	754252.PFREUD_08330	1.59e-156	442.0	COG1651@1|root,COG1651@2|Bacteria,2GKH8@201174|Actinobacteria	201174|Actinobacteria	O	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
gnl|extdb|FAM1414-i1-1.1_000490	754252.PFREUD_08340	4.25e-139	392.0	COG2259@1|root,COG2259@2|Bacteria,2IQEY@201174|Actinobacteria	201174|Actinobacteria	O	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
gnl|extdb|FAM1414-i1-1.1_000491	754252.PFREUD_08350	0.0	953.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4DNMV@85009|Propionibacteriales	201174|Actinobacteria	H	Mur ligase middle domain	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
gnl|extdb|FAM1414-i1-1.1_000492	754252.PFREUD_08360	2.39e-108	312.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4DQR5@85009|Propionibacteriales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
gnl|extdb|FAM1414-i1-1.1_000493	754252.PFREUD_08370	1.3e-285	783.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
gnl|extdb|FAM1414-i1-1.1_000494	754252.PFREUD_08380	0.0	1317.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4DNWJ@85009|Propionibacteriales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
gnl|extdb|FAM1414-i1-1.1_000495	754252.PFREUD_08390	2.31e-239	660.0	COG0387@1|root,COG0387@2|Bacteria,2GJWT@201174|Actinobacteria,4DP08@85009|Propionibacteriales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	chaA	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	iNJ661.Rv1607	Na_Ca_ex
gnl|extdb|FAM1414-i1-1.1_000496	754252.PFREUD_08400	1.12e-286	785.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4DNCF@85009|Propionibacteriales	201174|Actinobacteria	P	Integral membrane protein TerC family	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
gnl|extdb|FAM1414-i1-1.1_000497	754252.PFREUD_08410	4.19e-101	293.0	COG1846@1|root,COG1846@2|Bacteria,2I08G@201174|Actinobacteria,4DW84@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
gnl|extdb|FAM1414-i1-1.1_000498	754252.PFREUD_08420	1.38e-175	489.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria,4DQ75@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
gnl|extdb|FAM1414-i1-1.1_000499	754252.PFREUD_08440	0.0	1180.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4DPJ7@85009|Propionibacteriales	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
gnl|extdb|FAM1414-i1-1.1_000500	754252.PFREUD_08450	5.22e-65	198.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4DRJ6@85009|Propionibacteriales	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
gnl|extdb|FAM1414-i1-1.1_000501	754252.PFREUD_08460	7.2e-56	174.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4DRNG@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
gnl|extdb|FAM1414-i1-1.1_000502	754252.PFREUD_08480	0.0	1053.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4DNZK@85009|Propionibacteriales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
gnl|extdb|FAM1414-i1-1.1_000504	1032480.MLP_36030	2.34e-20	92.4	2DYDK@1|root,34999@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PQ-loop
gnl|extdb|FAM1414-i1-1.1_000505	754252.PFREUD_08510	7.59e-287	785.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4DNEG@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
gnl|extdb|FAM1414-i1-1.1_000506	754252.PFREUD_08530	4e-187	519.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4DNX3@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
gnl|extdb|FAM1414-i1-1.1_000507	754252.PFREUD_08540	5.06e-86	253.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4DR96@85009|Propionibacteriales	201174|Actinobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
gnl|extdb|FAM1414-i1-1.1_000508	754252.PFREUD_08550	1.21e-143	405.0	COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4DRFR@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpmB	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	3.1.3.85,5.4.2.11	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
gnl|extdb|FAM1414-i1-1.1_000509	754252.PFREUD_08560	5.2e-74	223.0	2EKIG@1|root,33E8D@2|Bacteria,2INGR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000510	754252.PFREUD_08570	3.14e-225	620.0	COG0451@1|root,COG0451@2|Bacteria,2GNH5@201174|Actinobacteria	201174|Actinobacteria	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
gnl|extdb|FAM1414-i1-1.1_000513	1150864.MILUP08_30162	2.51e-21	100.0	2AR9G@1|root,31GJC@2|Bacteria,2GN9V@201174|Actinobacteria,4DAW5@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4192)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4192
gnl|extdb|FAM1414-i1-1.1_000514	754252.PFREUD_08610	0.0	1728.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4DNGN@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
gnl|extdb|FAM1414-i1-1.1_000515	754252.PFREUD_08620	9.67e-317	862.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4DMZJ@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
gnl|extdb|FAM1414-i1-1.1_000516	754252.PFREUD_08630	0.0	1113.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4DTGZ@85009|Propionibacteriales	201174|Actinobacteria	C	Malic enzyme, NAD binding domain	PPA0888	-	1.1.1.38,4.1.1.101	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	-	R00214,R11074	RC00105,RC00282	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
gnl|extdb|FAM1414-i1-1.1_000517	754252.PFREUD_08640	1.37e-224	620.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4DRFZ@85009|Propionibacteriales	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
gnl|extdb|FAM1414-i1-1.1_000518	754252.PFREUD_08650	0.0	1472.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DP9N@85009|Propionibacteriales	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
gnl|extdb|FAM1414-i1-1.1_000519	754252.PFREUD_08660	3.79e-229	634.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4DN5C@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
gnl|extdb|FAM1414-i1-1.1_000521	754252.PFREUD_08680	3.34e-47	152.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4DS53@85009|Propionibacteriales	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
gnl|extdb|FAM1414-i1-1.1_000522	754252.PFREUD_08690	2.92e-137	389.0	2DQ2A@1|root,334FV@2|Bacteria,2I1WX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000523	754252.PFREUD_08710	0.0	1187.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4DNM0@85009|Propionibacteriales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
gnl|extdb|FAM1414-i1-1.1_000524	754252.PFREUD_08720	9e-297	808.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4DN32@85009|Propionibacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
gnl|extdb|FAM1414-i1-1.1_000525	754252.PFREUD_08730	2.61e-219	605.0	COG0613@1|root,COG0613@2|Bacteria,2GIZ5@201174|Actinobacteria,4DN6Z@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3097
gnl|extdb|FAM1414-i1-1.1_000526	754252.PFREUD_08740	5.46e-191	529.0	COG0483@1|root,COG0483@2|Bacteria,2GP74@201174|Actinobacteria,4DQB7@85009|Propionibacteriales	201174|Actinobacteria	G	Inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
gnl|extdb|FAM1414-i1-1.1_000527	754252.PFREUD_08750	4.47e-231	637.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4DP2Y@85009|Propionibacteriales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
gnl|extdb|FAM1414-i1-1.1_000528	754252.PFREUD_08760	2.32e-280	767.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4DPD2@85009|Propionibacteriales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
gnl|extdb|FAM1414-i1-1.1_000529	754252.PFREUD_08770	1.65e-162	456.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4DQEM@85009|Propionibacteriales	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
gnl|extdb|FAM1414-i1-1.1_000530	754252.PFREUD_08780	0.0	908.0	COG1409@1|root,COG1409@2|Bacteria,2IDNH@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,Pur_ac_phosph_N
gnl|extdb|FAM1414-i1-1.1_000535	754252.PFREUD_08830	0.0	900.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DPBG@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000536	754252.PFREUD_08840	6.13e-233	642.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4DPI2@85009|Propionibacteriales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
gnl|extdb|FAM1414-i1-1.1_000537	754252.PFREUD_08850	5.09e-107	308.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4DQJA@85009|Propionibacteriales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
gnl|extdb|FAM1414-i1-1.1_000538	754252.PFREUD_08860	9.92e-301	822.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4DNND@85009|Propionibacteriales	201174|Actinobacteria	S	Transporter associated domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
gnl|extdb|FAM1414-i1-1.1_000539	754252.PFREUD_08870	3.11e-221	610.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4DNEH@85009|Propionibacteriales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
gnl|extdb|FAM1414-i1-1.1_000540	1001240.GY21_08100	1.18e-07	57.8	2C5ND@1|root,3053S@2|Bacteria,2GSG7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000541	754252.PFREUD_08910	0.0	972.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4DN27@85009|Propionibacteriales	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
gnl|extdb|FAM1414-i1-1.1_000542	754252.PFREUD_08920	0.0	1189.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4DMZU@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
gnl|extdb|FAM1414-i1-1.1_000543	754252.PFREUD_08930	4.62e-81	240.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
gnl|extdb|FAM1414-i1-1.1_000544	754252.PFREUD_08940	1.4e-192	534.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4DPW4@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
gnl|extdb|FAM1414-i1-1.1_000545	754252.PFREUD_08950	3.56e-181	503.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4DP6A@85009|Propionibacteriales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
gnl|extdb|FAM1414-i1-1.1_000546	1203605.HMPREF1531_00752	2.35e-18	79.0	COG4576@1|root,COG4576@2|Bacteria,2GT97@201174|Actinobacteria,4DVTC@85009|Propionibacteriales	201174|Actinobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
gnl|extdb|FAM1414-i1-1.1_000475	754252.PFREUD_08180	1.89e-62	192.0	COG2076@1|root,COG2076@2|Bacteria,2IQND@201174|Actinobacteria,4DRIV@85009|Propionibacteriales	201174|Actinobacteria	P	Small Multidrug Resistance protein	sugE	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
gnl|extdb|FAM1414-i1-1.1_000481	754252.PFREUD_08240	2.88e-142	402.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4DNFI@85009|Propionibacteriales	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
gnl|extdb|FAM1414-i1-1.1_000482	754252.PFREUD_08250	5.35e-142	402.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4DNRI@85009|Propionibacteriales	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
gnl|extdb|FAM1414-i1-1.1_000503	754252.PFREUD_08490	1.42e-270	741.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4DNUG@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
gnl|extdb|FAM1414-i1-1.1_000531	754252.PFREUD_08790	2.59e-306	834.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
gnl|extdb|FAM1414-i1-1.1_000533	754252.PFREUD_08810	1.31e-236	650.0	COG0596@1|root,COG0596@2|Bacteria,2GNBX@201174|Actinobacteria,4DQ1B@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
gnl|extdb|FAM1414-i1-1.1_000548	754252.PFREUD_18300	2.04e-134	380.0	COG0494@1|root,COG0494@2|Bacteria,2HZ8R@201174|Actinobacteria,4DR5X@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_000549	754252.PFREUD_18290	0.0	1066.0	COG1404@1|root,COG1404@2|Bacteria,2GQDQ@201174|Actinobacteria	201174|Actinobacteria	O	S-layer domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SLH
gnl|extdb|FAM1414-i1-1.1_000550	754252.PFREUD_18270	0.0	976.0	COG1404@1|root,COG5492@1|root,COG1404@2|Bacteria,COG5492@2|Bacteria,2GQDQ@201174|Actinobacteria	201174|Actinobacteria	O	S-layer domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SLH
gnl|extdb|FAM1414-i1-1.1_000551	754252.PFREUD_18290	7.89e-15	83.2	COG1404@1|root,COG1404@2|Bacteria,2GQDQ@201174|Actinobacteria	201174|Actinobacteria	O	S-layer domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SLH
gnl|extdb|FAM1414-i1-1.1_000552	754252.PFREUD_18260	4.61e-126	364.0	COG5479@1|root,COG5479@2|Bacteria	2|Bacteria	M	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Excalibur,LGFP,Peptidase_M15_4
gnl|extdb|FAM1414-i1-1.1_000553	1121933.AUHH01000001_gene2207	7.9e-305	842.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4DNIW@85009|Propionibacteriales	201174|Actinobacteria	L	ERCC3/RAD25/XPB C-terminal helicase	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
gnl|extdb|FAM1414-i1-1.1_000554	754252.PFREUD_18230	0.0	1446.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria,4DP0U@85009|Propionibacteriales	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
gnl|extdb|FAM1414-i1-1.1_000556	754252.PFREUD_18210	2.81e-88	259.0	COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4DQZ2@85009|Propionibacteriales	201174|Actinobacteria	K	Cold shock protein domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
gnl|extdb|FAM1414-i1-1.1_000557	754252.PFREUD_18200	4.19e-195	540.0	28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4DQ8F@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
gnl|extdb|FAM1414-i1-1.1_000558	1229203.KI301992_gene268	4.4e-05	47.4	2ETMT@1|root,33M5J@2|Bacteria,2IQ41@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2530)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2530
gnl|extdb|FAM1414-i1-1.1_000561	754252.PFREUD_18160	2.03e-273	747.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4DP4I@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
gnl|extdb|FAM1414-i1-1.1_000562	754252.PFREUD_18150	1.45e-160	449.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4DP20@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix diphteria tox regulatory element	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
gnl|extdb|FAM1414-i1-1.1_000563	754252.PFREUD_18140	3e-75	224.0	COG3118@1|root,COG3118@2|Bacteria,2I2FB@201174|Actinobacteria,4DWYI@85009|Propionibacteriales	201174|Actinobacteria	O	Thioredoxin	trxA	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
gnl|extdb|FAM1414-i1-1.1_000564	754252.PFREUD_18120	2.12e-81	241.0	2E4BT@1|root,33YQ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000565	754252.PFREUD_18110	1.46e-200	554.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
gnl|extdb|FAM1414-i1-1.1_000566	754252.PFREUD_18100	1.11e-141	400.0	COG1335@1|root,COG1335@2|Bacteria,2GKZR@201174|Actinobacteria,4DSEZ@85009|Propionibacteriales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
gnl|extdb|FAM1414-i1-1.1_000569	754252.PFREUD_18070	0.0	924.0	COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4DPKI@85009|Propionibacteriales	201174|Actinobacteria	G	UTP--glucose-1-phosphate uridylyltransferase	ugp	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
gnl|extdb|FAM1414-i1-1.1_000570	767029.HMPREF9154_2601	1.51e-11	63.2	2DDCJ@1|root,2ZHHZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000571	754252.PFREUD_18050	3.03e-93	273.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4DRP7@85009|Propionibacteriales	201174|Actinobacteria	M	Large-conductance mechanosensitive channel, MscL	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
gnl|extdb|FAM1414-i1-1.1_000572	754252.PFREUD_18030	1.71e-127	365.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ChapFlgA,RcpC,SAF
gnl|extdb|FAM1414-i1-1.1_000574	754252.PFREUD_18010	5.36e-157	441.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4DR3Y@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
gnl|extdb|FAM1414-i1-1.1_000575	754252.PFREUD_18000	1.35e-299	818.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4DNAW@85009|Propionibacteriales	201174|Actinobacteria	H	MoeA domain protein domain I and II	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
gnl|extdb|FAM1414-i1-1.1_000577	1122994.AUFR01000027_gene93	2.79e-97	292.0	2ETNC@1|root,33M63@2|Bacteria,2GKI3@201174|Actinobacteria,4DS5B@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000580	930171.Asphe3_22540	2.67e-39	131.0	2EBC3@1|root,335CU@2|Bacteria,2GUEZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000582	1184609.KILIM_019_00520	4.95e-91	267.0	COG0629@1|root,COG0629@2|Bacteria,2IMCN@201174|Actinobacteria	201174|Actinobacteria	L	single-stranded DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	SSB
gnl|extdb|FAM1414-i1-1.1_000583	1032480.MLP_37270	0.0	1065.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria,4DNM4@85009|Propionibacteriales	201174|Actinobacteria	U	Type IV secretory pathway VirD4	-	-	-	-	-	-	-	-	-	-	-	-	TraG-D_C
gnl|extdb|FAM1414-i1-1.1_000584	1184609.KILIM_078_00170	3.19e-93	276.0	29K3G@1|root,3070W@2|Bacteria,2IINK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000585	1121933.AUHH01000008_gene1174	0.0	930.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4DP1Q@85009|Propionibacteriales	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000586	1184609.KILIM_078_00190	1.78e-177	496.0	28JTD@1|root,2Z9IP@2|Bacteria,2IB6M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000587	1172185.KB911513_gene4544	2.05e-306	848.0	2CB9N@1|root,348B8@2|Bacteria,2GP80@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000588	1184609.KILIM_078_00210	0.0	932.0	28IJ8@1|root,2Z8K6@2|Bacteria,2GIV3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EccE
gnl|extdb|FAM1414-i1-1.1_000589	930171.Asphe3_22450	3.74e-227	637.0	COG3266@1|root,COG3266@2|Bacteria,2GN4E@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
gnl|extdb|FAM1414-i1-1.1_000591	1184609.KILIM_078_00250	4.68e-48	154.0	2E1EX@1|root,32WTQ@2|Bacteria,2IRYZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000592	1121933.AUHH01000008_gene1196	0.0	1087.0	COG1061@1|root,COG1061@2|Bacteria,2HJPR@201174|Actinobacteria	201174|Actinobacteria	KL	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	T5orf172
gnl|extdb|FAM1414-i1-1.1_000593	1121933.AUHH01000008_gene1196	6.69e-102	315.0	COG1061@1|root,COG1061@2|Bacteria,2HJPR@201174|Actinobacteria	201174|Actinobacteria	KL	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	T5orf172
gnl|extdb|FAM1414-i1-1.1_000594	1273125.Rrhod_4375	0.0	956.0	COG1479@1|root,COG1479@2|Bacteria,2ID2S@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
gnl|extdb|FAM1414-i1-1.1_000595	1121020.JIAG01000002_gene809	2.69e-67	208.0	2B8NN@1|root,321Y4@2|Bacteria,2H652@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000596	1121924.ATWH01000002_gene3724	2.94e-67	214.0	COG0270@1|root,COG0270@2|Bacteria,2I8R8@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
gnl|extdb|FAM1414-i1-1.1_000598	1089455.MOPEL_015_00020	1.04e-220	609.0	COG0464@1|root,COG0464@2|Bacteria,2GN05@201174|Actinobacteria,4F7QM@85018|Dermatophilaceae	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
gnl|extdb|FAM1414-i1-1.1_000599	1089455.MOPEL_015_00030	0.0	1642.0	COG1404@1|root,COG1404@2|Bacteria,2HVT3@201174|Actinobacteria,4F7IX@85018|Dermatophilaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
gnl|extdb|FAM1414-i1-1.1_000600	930171.Asphe3_21690	1.11e-167	477.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,1W7T5@1268|Micrococcaceae	201174|Actinobacteria	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
gnl|extdb|FAM1414-i1-1.1_000601	930171.Asphe3_21680	3.73e-68	207.0	2EBVN@1|root,335V2@2|Bacteria,2IR7Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000602	1184609.KILIM_155_00010	4.25e-260	716.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4F7MV@85018|Dermatophilaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_000559	754252.PFREUD_18180	7.99e-317	868.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4DNIA@85009|Propionibacteriales	201174|Actinobacteria	S	Permease family	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
gnl|extdb|FAM1414-i1-1.1_000573	754252.PFREUD_18020	1.18e-49	162.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
gnl|extdb|FAM1414-i1-1.1_000576	754252.PFREUD_17990	4.62e-168	469.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,4DQM3@85009|Propionibacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
gnl|extdb|FAM1414-i1-1.1_000581	1184609.KILIM_019_00530	7.72e-122	348.0	28Q31@1|root,2ZCKT@2|Bacteria,2IFAQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000590	1184609.KILIM_078_00230	1.62e-61	189.0	2E3QT@1|root,32YNN@2|Bacteria,2IKY3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000597	930171.Asphe3_21770	0.0	1990.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,1WA5R@1268|Micrococcaceae	201174|Actinobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
gnl|extdb|FAM1414-i1-1.1_000603	754252.PFREUD_24230	3.61e-41	145.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_000604	1173025.GEI7407_3101	6.82e-36	146.0	COG4713@1|root,COG4713@2|Bacteria,1G496@1117|Cyanobacteria,1HAGJ@1150|Oscillatoriales	1117|Cyanobacteria	S	Predicted membrane protein (DUF2142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
gnl|extdb|FAM1414-i1-1.1_000605	754252.PFREUD_00560	1.6e-247	737.0	COG1705@1|root,COG5479@1|root,COG1705@2|Bacteria,COG5479@2|Bacteria	2|Bacteria	M	isomerase activity	acm2	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,LGFP,Phospholip_A2_3
gnl|extdb|FAM1414-i1-1.1_000607	754252.PFREUD_00570	5.87e-300	816.0	COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4DNBC@85009|Propionibacteriales	201174|Actinobacteria	M	UDP-galactopyranose mutase	glf	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3809c	GLF,NAD_binding_8
gnl|extdb|FAM1414-i1-1.1_000608	754252.PFREUD_00580	0.0	1321.0	COG1216@1|root,COG1216@2|Bacteria,2GM9N@201174|Actinobacteria,4DPRT@85009|Propionibacteriales	201174|Actinobacteria	S	Glycosyltransferase like family 2	glfT	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009273,GO:0009987,GO:0010383,GO:0016020,GO:0016043,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0022607,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0035250,GO:0035496,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046483,GO:0052573,GO:0055086,GO:0070589,GO:0070592,GO:0071554,GO:0071555,GO:0071704,GO:0071766,GO:0071769,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901576,GO:1903509	2.4.1.288	ko:K16650	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	iNJ661.Rv3808c	Glyco_tranf_2_3
gnl|extdb|FAM1414-i1-1.1_000609	754252.PFREUD_00590	8.88e-216	596.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4DQ8I@85009|Propionibacteriales	201174|Actinobacteria	GM	ABC-2 type transporter	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
gnl|extdb|FAM1414-i1-1.1_000611	754252.PFREUD_00610	0.0	1575.0	COG1216@1|root,COG2327@1|root,COG1216@2|Bacteria,COG2327@2|Bacteria,2IK1R@201174|Actinobacteria	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
gnl|extdb|FAM1414-i1-1.1_000612	754252.PFREUD_00620	1.16e-205	568.0	COG1215@1|root,COG1215@2|Bacteria,2HFAF@201174|Actinobacteria,4DTEA@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
gnl|extdb|FAM1414-i1-1.1_000613	754252.PFREUD_00630	8.93e-223	615.0	COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,4DN24@85009|Propionibacteriales	201174|Actinobacteria	M	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
gnl|extdb|FAM1414-i1-1.1_000614	754252.PFREUD_00640	1.66e-85	252.0	COG0526@1|root,COG0526@2|Bacteria,2IKMI@201174|Actinobacteria,4DRPF@85009|Propionibacteriales	201174|Actinobacteria	CO	Thioredoxin	thiX	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
gnl|extdb|FAM1414-i1-1.1_000615	754252.PFREUD_00650	1.3e-92	272.0	2AN8T@1|root,327DN@2|Bacteria,2I81P@201174|Actinobacteria,4DWJ2@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
gnl|extdb|FAM1414-i1-1.1_000616	754252.PFREUD_00670	6.35e-188	522.0	COG0204@1|root,COG0204@2|Bacteria,2IA3W@201174|Actinobacteria,4DWQN@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
gnl|extdb|FAM1414-i1-1.1_000617	754252.PFREUD_00680	6.37e-190	527.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4DQTE@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
gnl|extdb|FAM1414-i1-1.1_000618	754252.PFREUD_00690	1.16e-286	783.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4DP4Y@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
gnl|extdb|FAM1414-i1-1.1_000619	754252.PFREUD_00700	0.0	962.0	COG0280@1|root,COG0280@2|Bacteria,2GJ5U@201174|Actinobacteria,4DN2E@85009|Propionibacteriales	201174|Actinobacteria	C	belongs to the CobB CobQ family	pta	GO:0005575,GO:0005576	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
gnl|extdb|FAM1414-i1-1.1_000620	754252.PFREUD_00710	0.0	2243.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria	201174|Actinobacteria	L	helicase	helZ	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
gnl|extdb|FAM1414-i1-1.1_000621	754252.PFREUD_23030	0.0	911.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SLH
gnl|extdb|FAM1414-i1-1.1_000623	754252.PFREUD_23010	1.97e-188	523.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4DN5G@85009|Propionibacteriales	201174|Actinobacteria	L	Xylose isomerase-like TIM barrel	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
gnl|extdb|FAM1414-i1-1.1_000624	754252.PFREUD_23000	0.0	1280.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	PPA2234	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
gnl|extdb|FAM1414-i1-1.1_000625	754252.PFREUD_22990	0.0	997.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K06609	-	-	-	-	ko00000,ko02000	2.A.1.1.26	-	-	Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000626	754252.PFREUD_22980	9.48e-195	539.0	COG3622@1|root,COG3622@2|Bacteria,2GKPC@201174|Actinobacteria,4DR0F@85009|Propionibacteriales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
gnl|extdb|FAM1414-i1-1.1_000627	754252.PFREUD_22970	6.64e-235	647.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
gnl|extdb|FAM1414-i1-1.1_000628	754252.PFREUD_22960	2.77e-134	380.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4DQD6@85009|Propionibacteriales	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
gnl|extdb|FAM1414-i1-1.1_000629	754252.PFREUD_22950	1.19e-232	641.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4DQ7J@85009|Propionibacteriales	201174|Actinobacteria	ET	amino acid	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
gnl|extdb|FAM1414-i1-1.1_000630	754252.PFREUD_22940	3.45e-191	533.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4DQ7J@85009|Propionibacteriales	201174|Actinobacteria	ET	amino acid	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
gnl|extdb|FAM1414-i1-1.1_000631	754252.PFREUD_22930	7.93e-197	548.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4DQ7J@85009|Propionibacteriales	201174|Actinobacteria	ET	amino acid	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
gnl|extdb|FAM1414-i1-1.1_000632	754252.PFREUD_22920	5.93e-215	595.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4DQAE@85009|Propionibacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	yecS	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_000634	754252.PFREUD_22900	4.77e-177	497.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4DR1C@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	yqjI	-	-	-	-	-	-	-	-	-	-	-	PadR
gnl|extdb|FAM1414-i1-1.1_000635	754252.PFREUD_22890	0.0	1418.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2H2H9@201174|Actinobacteria,4DNXS@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
gnl|extdb|FAM1414-i1-1.1_000636	754252.PFREUD_22880	9.76e-300	816.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4DQQR@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
gnl|extdb|FAM1414-i1-1.1_000637	754252.PFREUD_22870	8.2e-102	295.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
gnl|extdb|FAM1414-i1-1.1_000638	754252.PFREUD_22860	2.2e-252	692.0	COG1995@1|root,COG1995@2|Bacteria,2GRPG@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the PdxA family	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
gnl|extdb|FAM1414-i1-1.1_000639	754252.PFREUD_22850	5.78e-290	795.0	COG2610@1|root,COG2610@2|Bacteria,2GITQ@201174|Actinobacteria,4DN1V@85009|Propionibacteriales	201174|Actinobacteria	EG	GntP family permease	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
gnl|extdb|FAM1414-i1-1.1_000640	754252.PFREUD_22840	4.29e-226	622.0	COG1082@1|root,COG1082@2|Bacteria,2IB5E@201174|Actinobacteria	201174|Actinobacteria	G	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
gnl|extdb|FAM1414-i1-1.1_000641	754252.PFREUD_22830	4.63e-312	850.0	COG2271@1|root,COG2271@2|Bacteria,2IE55@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08194	-	-	-	-	ko00000,ko02000	2.A.1.14.7	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_000642	1221522.B723_06785	1.79e-38	138.0	COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,1RNCH@1236|Gammaproteobacteria,1YR7K@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
gnl|extdb|FAM1414-i1-1.1_000643	754252.PFREUD_25090	0.0	882.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_000610	754252.PFREUD_00600	3.59e-174	486.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4DP9X@85009|Propionibacteriales	201174|Actinobacteria	GM	ATPases associated with a variety of cellular activities	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
gnl|extdb|FAM1414-i1-1.1_000633	754252.PFREUD_22910	1.28e-181	506.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DNUK@85009|Propionibacteriales	201174|Actinobacteria	E	Polar amino acid transport system	atrC	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000645	1274.HX89_01350	4.33e-23	96.3	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,1ZWJX@145357|Dermacoccaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_000646	1292373.H640_03326	1.77e-123	380.0	COG1203@1|root,COG1203@2|Bacteria,2GMM0@201174|Actinobacteria	201174|Actinobacteria	L	CRISPR-associated helicase Cas3	cas3	-	-	ko:K07012,ko:K19123	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	CRISPR_Cse1,DEAD,Helicase_C
gnl|extdb|FAM1414-i1-1.1_000647	1170318.PALO_00040	6.94e-243	715.0	COG1203@1|root,COG1203@2|Bacteria,2GMM0@201174|Actinobacteria	201174|Actinobacteria	L	CRISPR-associated helicase Cas3	cas3	-	-	ko:K07012,ko:K19123	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	CRISPR_Cse1,DEAD,Helicase_C
gnl|extdb|FAM1414-i1-1.1_000648	754252.PFREUD_03840	1.14e-143	405.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4DP0B@85009|Propionibacteriales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
gnl|extdb|FAM1414-i1-1.1_000649	754252.PFREUD_03830	5.65e-60	185.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4DRUM@85009|Propionibacteriales	201174|Actinobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
gnl|extdb|FAM1414-i1-1.1_000651	754252.PFREUD_03810	1.87e-155	438.0	COG3764@1|root,COG3764@2|Bacteria,2HF6P@201174|Actinobacteria,4DWEQ@85009|Propionibacteriales	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
gnl|extdb|FAM1414-i1-1.1_000652	1231336.L248_2822	2.21e-07	62.4	COG3827@1|root,COG4932@1|root,COG3827@2|Bacteria,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F4FM@33958|Lactobacillaceae	91061|Bacilli	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind,Gram_pos_anchor,SdrD_B
gnl|extdb|FAM1414-i1-1.1_000653	754252.PFREUD_03790	0.0	1636.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GPUP@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
gnl|extdb|FAM1414-i1-1.1_000654	754252.PFREUD_03780	9.06e-266	733.0	COG4243@1|root,COG4243@2|Bacteria,2HG56@201174|Actinobacteria	201174|Actinobacteria	Q	Vitamin k epoxide reductase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000655	754252.PFREUD_03770	8.06e-183	516.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,HTH_20,HTH_IclR
gnl|extdb|FAM1414-i1-1.1_000656	754252.PFREUD_03760	2.57e-64	196.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
gnl|extdb|FAM1414-i1-1.1_000658	754252.PFREUD_03750	1.22e-309	843.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DP7V@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1559	PALP,Thr_dehydrat_C
gnl|extdb|FAM1414-i1-1.1_000661	1121019.AUMN01000005_gene2701	0.000389	47.8	2EGCD@1|root,33A46@2|Bacteria,2HNPD@201174|Actinobacteria,1WA96@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mycobact_memb
gnl|extdb|FAM1414-i1-1.1_000662	754252.PFREUD_03610	3.34e-164	464.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
gnl|extdb|FAM1414-i1-1.1_000663	754252.PFREUD_03610	8.31e-22	92.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
gnl|extdb|FAM1414-i1-1.1_000665	754252.PFREUD_03590	4.64e-153	432.0	COG2356@1|root,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria,4DQTH@85009|Propionibacteriales	201174|Actinobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,Excalibur
gnl|extdb|FAM1414-i1-1.1_000667	754252.PFREUD_03570	3.35e-289	793.0	COG2704@1|root,COG2704@2|Bacteria,2GKYB@201174|Actinobacteria	201174|Actinobacteria	S	Anaerobic c4-dicarboxylate	PPA1043	-	-	ko:K07791	-	-	-	-	ko00000,ko02000	2.A.13.1	-	-	DcuA_DcuB
gnl|extdb|FAM1414-i1-1.1_000668	754252.PFREUD_03560	0.0	2080.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4DN78@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
gnl|extdb|FAM1414-i1-1.1_000672	1206733.BAGC01000110_gene6635	6.67e-11	61.2	2BKTU@1|root,32FA2@2|Bacteria,2HZ4Z@201174|Actinobacteria,4G4ZQ@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000674	754252.PFREUD_03460	3.25e-188	526.0	COG3786@1|root,COG3786@2|Bacteria,2GNX8@201174|Actinobacteria,4DSUC@85009|Propionibacteriales	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
gnl|extdb|FAM1414-i1-1.1_000675	754252.PFREUD_03450	4.91e-173	489.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Band 7 protein	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
gnl|extdb|FAM1414-i1-1.1_000677	754252.PFREUD_03410	3.25e-223	615.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4DNBF@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
gnl|extdb|FAM1414-i1-1.1_000678	754252.PFREUD_03400	0.0	897.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	aroP	-	-	ko:K03293,ko:K11732	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.1	-	-	AA_permease
gnl|extdb|FAM1414-i1-1.1_000680	754252.PFREUD_03370	8.4e-198	548.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4DSCS@85009|Propionibacteriales	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
gnl|extdb|FAM1414-i1-1.1_000683	754252.PFREUD_03340	0.0	1082.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DQX3@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
gnl|extdb|FAM1414-i1-1.1_000684	754252.PFREUD_03330	2.75e-125	357.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4DR1C@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	padR	-	-	-	-	-	-	-	-	-	-	-	PadR
gnl|extdb|FAM1414-i1-1.1_000686	1122998.AUHZ01000032_gene57	9.01e-243	668.0	COG0798@1|root,COG0798@2|Bacteria,2GJ4H@201174|Actinobacteria,4DP3B@85009|Propionibacteriales	201174|Actinobacteria	P	Sodium Bile acid symporter family	arsB	-	1.20.4.1	ko:K03325,ko:K03741	-	-	-	-	ko00000,ko01000,ko02000	2.A.59	-	-	SBF
gnl|extdb|FAM1414-i1-1.1_000687	1122998.AUHZ01000032_gene58	0.0	922.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4DQ82@85009|Propionibacteriales	201174|Actinobacteria	T	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C
gnl|extdb|FAM1414-i1-1.1_000688	1122998.AUHZ01000032_gene59	2.95e-77	230.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
gnl|extdb|FAM1414-i1-1.1_000689	1122998.AUHZ01000032_gene60	2.49e-65	202.0	2DMHQ@1|root,32RMG@2|Bacteria,2IQ7H@201174|Actinobacteria	201174|Actinobacteria	S	Arsenical resistance operon trans-acting repressor	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
gnl|extdb|FAM1414-i1-1.1_000690	1122998.AUHZ01000032_gene61	0.0	1131.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
gnl|extdb|FAM1414-i1-1.1_000691	1122998.AUHZ01000032_gene62	2.58e-185	516.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4DTYI@85009|Propionibacteriales	201174|Actinobacteria	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
gnl|extdb|FAM1414-i1-1.1_000692	1125718.HMPREF1318_1520	0.0	1060.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,4D3AT@85005|Actinomycetales	201174|Actinobacteria	L	the current gene model (or a revised gene model) may contain a premature stop	-	-	-	-	-	-	-	-	-	-	-	-	rve
gnl|extdb|FAM1414-i1-1.1_000694	754252.PFREUD_23050	6.99e-130	369.0	COG1961@1|root,COG1961@2|Bacteria,2INBC@201174|Actinobacteria	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
gnl|extdb|FAM1414-i1-1.1_000679	754252.PFREUD_03380	3.47e-188	524.0	COG2145@1|root,COG2145@2|Bacteria,2IC73@201174|Actinobacteria,4DUM7@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
gnl|extdb|FAM1414-i1-1.1_000681	754252.PFREUD_03360	1.14e-175	492.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4DR48@85009|Propionibacteriales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TENA_THI-4,TMP-TENI
gnl|extdb|FAM1414-i1-1.1_000682	754252.PFREUD_03350	4.46e-294	805.0	COG1457@1|root,COG1457@2|Bacteria	2|Bacteria	F	cytosine transport	cytX	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
gnl|extdb|FAM1414-i1-1.1_000695	754252.PFREUD_00110	2.82e-98	300.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Polysacc_deac_1,SLH,VCBS
gnl|extdb|FAM1414-i1-1.1_000696	754252.PFREUD_00110	3.95e-285	785.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Polysacc_deac_1,SLH,VCBS
gnl|extdb|FAM1414-i1-1.1_000698	754252.PFREUD_00090	1.86e-304	831.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4DNK0@85009|Propionibacteriales	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
gnl|extdb|FAM1414-i1-1.1_000699	754252.PFREUD_00080	4.05e-266	730.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4DN43@85009|Propionibacteriales	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
gnl|extdb|FAM1414-i1-1.1_000700	754252.PFREUD_00070	0.0	1506.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4DP5J@85009|Propionibacteriales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
gnl|extdb|FAM1414-i1-1.1_000701	754252.PFREUD_00060	7.34e-218	603.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4DNEX@85009|Propionibacteriales	201174|Actinobacteria	V	COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000702	754252.PFREUD_00050	2.86e-308	839.0	COG0451@1|root,COG0451@2|Bacteria,2GJJG@201174|Actinobacteria	201174|Actinobacteria	GM	Epimerase dehydratase	sqdB	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
gnl|extdb|FAM1414-i1-1.1_000703	754252.PFREUD_00040	5.46e-279	763.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4DNSP@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase Family 4	sqdX	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
gnl|extdb|FAM1414-i1-1.1_000704	754252.PFREUD_00030	1.03e-141	400.0	COG0789@1|root,COG0789@2|Bacteria,2I9B3@201174|Actinobacteria,4DSCP@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
gnl|extdb|FAM1414-i1-1.1_000705	754252.PFREUD_00020	0.0	901.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DPZK@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000706	754252.PFREUD_00010	0.0	946.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4DMZ1@85009|Propionibacteriales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
gnl|extdb|FAM1414-i1-1.1_000707	754252.PFREUD_24220	1.22e-19	80.1	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
gnl|extdb|FAM1414-i1-1.1_000708	754252.PFREUD_24210	5.01e-91	267.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4DSDD@85009|Propionibacteriales	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0008150,GO:0040007	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
gnl|extdb|FAM1414-i1-1.1_000709	754252.PFREUD_24200	1.76e-83	246.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4DSGI@85009|Propionibacteriales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
gnl|extdb|FAM1414-i1-1.1_000711	1122994.AUFR01000026_gene128	5.42e-81	251.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4DQRW@85009|Propionibacteriales	201174|Actinobacteria	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
gnl|extdb|FAM1414-i1-1.1_000713	754252.PFREUD_24150	4.6e-186	530.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4DNHI@85009|Propionibacteriales	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
gnl|extdb|FAM1414-i1-1.1_000714	754252.PFREUD_24140	5.01e-228	629.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4DNPD@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
gnl|extdb|FAM1414-i1-1.1_000715	754252.PFREUD_24120	1.94e-100	291.0	COG1765@1|root,COG1765@2|Bacteria,2IRWN@201174|Actinobacteria	201174|Actinobacteria	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
gnl|extdb|FAM1414-i1-1.1_000716	754252.PFREUD_24110	5.27e-74	221.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4DRDT@85009|Propionibacteriales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
gnl|extdb|FAM1414-i1-1.1_000717	754252.PFREUD_24100	9.42e-232	638.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4DPPP@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
gnl|extdb|FAM1414-i1-1.1_000718	754252.PFREUD_24090	3.32e-301	823.0	COG1653@1|root,COG1653@2|Bacteria,2GR9A@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
gnl|extdb|FAM1414-i1-1.1_000719	754252.PFREUD_24080	7.49e-179	497.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
gnl|extdb|FAM1414-i1-1.1_000720	754252.PFREUD_24070	0.0	1211.0	COG0515@1|root,COG0515@2|Bacteria,2GM4A@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
gnl|extdb|FAM1414-i1-1.1_000721	1122997.AUDD01000011_gene2065	6.85e-60	222.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria,4DQW4@85009|Propionibacteriales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000722	754252.PFREUD_24050	0.0	951.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria,4DWGG@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000723	754252.PFREUD_24040	0.0	989.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4DMZV@85009|Propionibacteriales	201174|Actinobacteria	J	Probable RNA and SrmB- binding site of polymerase A	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
gnl|extdb|FAM1414-i1-1.1_000724	754252.PFREUD_24030	0.0	977.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4DNMY@85009|Propionibacteriales	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
gnl|extdb|FAM1414-i1-1.1_000725	754252.PFREUD_24020	2.52e-210	588.0	COG0614@1|root,COG0614@2|Bacteria,2GKZJ@201174|Actinobacteria,4DPXR@85009|Propionibacteriales	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
gnl|extdb|FAM1414-i1-1.1_000726	754252.PFREUD_24010	3.43e-237	657.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4DN77@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
gnl|extdb|FAM1414-i1-1.1_000728	754252.PFREUD_23980	1.63e-52	166.0	COG4270@1|root,COG4270@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,DoxX_2
gnl|extdb|FAM1414-i1-1.1_000729	754252.PFREUD_23970	7.18e-153	429.0	COG0702@1|root,COG0702@2|Bacteria,2IC5H@201174|Actinobacteria	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
gnl|extdb|FAM1414-i1-1.1_000730	754252.PFREUD_23960	9.4e-150	423.0	COG1309@1|root,COG1309@2|Bacteria,2GJQY@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
gnl|extdb|FAM1414-i1-1.1_000731	754252.PFREUD_23950	0.0	1221.0	COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DP70@85009|Propionibacteriales	201174|Actinobacteria	P	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
gnl|extdb|FAM1414-i1-1.1_000732	754252.PFREUD_23930	4.68e-149	421.0	COG4291@1|root,COG4291@2|Bacteria,2IIVD@201174|Actinobacteria,4DQSM@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
gnl|extdb|FAM1414-i1-1.1_000734	754252.PFREUD_23910	1.73e-306	835.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4DPEX@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
gnl|extdb|FAM1414-i1-1.1_000735	754252.PFREUD_23900	1.33e-124	355.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4DQQD@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
gnl|extdb|FAM1414-i1-1.1_000736	754252.PFREUD_23890	7.21e-205	567.0	COG3588@1|root,COG3588@2|Bacteria,2GN1A@201174|Actinobacteria	201174|Actinobacteria	G	Aldolase	fda	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
gnl|extdb|FAM1414-i1-1.1_000697	754252.PFREUD_00100	1.95e-102	301.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4DR8Q@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
gnl|extdb|FAM1414-i1-1.1_000710	754252.PFREUD_24190	2.27e-229	634.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4DQ6T@85009|Propionibacteriales	201174|Actinobacteria	U	60Kd inner membrane protein	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
gnl|extdb|FAM1414-i1-1.1_000712	754252.PFREUD_24170	3.88e-176	491.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4DR7I@85009|Propionibacteriales	201174|Actinobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
gnl|extdb|FAM1414-i1-1.1_000733	754252.PFREUD_23920	5.8e-252	691.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4DNMA@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
gnl|extdb|FAM1414-i1-1.1_000737	1210046.B277_05364	4.94e-16	83.6	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4FJZU@85021|Intrasporangiaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
gnl|extdb|FAM1414-i1-1.1_000738	754252.PFREUD_09150	1.52e-119	341.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4DQZK@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
gnl|extdb|FAM1414-i1-1.1_000740	754252.PFREUD_09170	1.01e-183	511.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,4DPIC@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	mntB	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000741	754252.PFREUD_09180	6.32e-225	620.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4DNM9@85009|Propionibacteriales	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
gnl|extdb|FAM1414-i1-1.1_000742	754252.PFREUD_09190	0.0	963.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4DPNB@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
gnl|extdb|FAM1414-i1-1.1_000743	754252.PFREUD_09200	1.21e-213	590.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4DNUU@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
gnl|extdb|FAM1414-i1-1.1_000744	754252.PFREUD_09210	0.0	1079.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4DN9N@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
gnl|extdb|FAM1414-i1-1.1_000745	754252.PFREUD_09220	1.91e-236	650.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
gnl|extdb|FAM1414-i1-1.1_000747	754252.PFREUD_09240	2.21e-177	494.0	28HIR@1|root,30UAY@2|Bacteria,2I860@201174|Actinobacteria,4DWJ7@85009|Propionibacteriales	201174|Actinobacteria	C	succinate dehydrogenase	sdhC_1	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
gnl|extdb|FAM1414-i1-1.1_000748	754252.PFREUD_09250	0.0	1416.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DN0E@85009|Propionibacteriales	201174|Actinobacteria	C	succinate dehydrogenase	sdhA	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
gnl|extdb|FAM1414-i1-1.1_000749	754252.PFREUD_09260	3.43e-186	516.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4DPU6@85009|Propionibacteriales	201174|Actinobacteria	C	Succinate dehydrogenase fumarate reductase	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_7,Fer4_8
gnl|extdb|FAM1414-i1-1.1_000753	754252.PFREUD_09300	2.53e-164	458.0	COG5423@1|root,COG5423@2|Bacteria	2|Bacteria	M	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
gnl|extdb|FAM1414-i1-1.1_000754	754252.PFREUD_09310	0.0	917.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4DNK2@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	dldH5	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
gnl|extdb|FAM1414-i1-1.1_000755	754252.PFREUD_09320	5.7e-199	551.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4DR0A@85009|Propionibacteriales	201174|Actinobacteria	J	hydrolases of the HAD superfamily	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
gnl|extdb|FAM1414-i1-1.1_000756	754252.PFREUD_09330	1.35e-164	466.0	2BYTB@1|root,33S2I@2|Bacteria,2IIS4@201174|Actinobacteria,4DSUF@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000757	754252.PFREUD_09340	3.83e-242	667.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DNJJ@85009|Propionibacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
gnl|extdb|FAM1414-i1-1.1_000758	754252.PFREUD_09350	5.09e-236	650.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4DPV4@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
gnl|extdb|FAM1414-i1-1.1_000759	754252.PFREUD_09360	4.44e-225	621.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
gnl|extdb|FAM1414-i1-1.1_000760	754252.PFREUD_09370	4.07e-218	603.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
gnl|extdb|FAM1414-i1-1.1_000761	754252.PFREUD_09380	1.69e-178	497.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4DQBA@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
gnl|extdb|FAM1414-i1-1.1_000762	754252.PFREUD_09390	0.0	1340.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4DTZJ@85009|Propionibacteriales	201174|Actinobacteria	E	Dienelactone hydrolase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
gnl|extdb|FAM1414-i1-1.1_000763	754252.PFREUD_09400	2.77e-119	340.0	299E4@1|root,2ZWGX@2|Bacteria,2GM90@201174|Actinobacteria,4DQ7U@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3145
gnl|extdb|FAM1414-i1-1.1_000764	754252.PFREUD_09410	5.25e-297	811.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,4DN2J@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
gnl|extdb|FAM1414-i1-1.1_000765	754252.PFREUD_09420	4.66e-48	154.0	COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
gnl|extdb|FAM1414-i1-1.1_000766	754252.PFREUD_09430	8.54e-213	589.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4DP78@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
gnl|extdb|FAM1414-i1-1.1_000767	754252.PFREUD_09440	4.95e-219	605.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4DPZC@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl transferase domain	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
gnl|extdb|FAM1414-i1-1.1_000768	754252.PFREUD_09450	7.47e-273	748.0	COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria,4DNAE@85009|Propionibacteriales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
gnl|extdb|FAM1414-i1-1.1_000769	754252.PFREUD_09460	1.73e-289	790.0	COG1448@1|root,COG1448@2|Bacteria,2I96J@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class I and II	-	-	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
gnl|extdb|FAM1414-i1-1.1_000770	754252.PFREUD_09470	0.0	1881.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DNUA@85009|Propionibacteriales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
gnl|extdb|FAM1414-i1-1.1_000771	754252.PFREUD_09480	5.23e-97	282.0	2B57P@1|root,32TPU@2|Bacteria,2I89I@201174|Actinobacteria,4DQZ6@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
gnl|extdb|FAM1414-i1-1.1_000772	754252.PFREUD_09490	0.0	1129.0	COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria,4DWN0@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	ywjA	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_000773	754252.PFREUD_09500	8.16e-103	297.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4DQU3@85009|Propionibacteriales	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20)	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
gnl|extdb|FAM1414-i1-1.1_000774	754252.PFREUD_09510	0.0	880.0	COG0531@1|root,COG0531@2|Bacteria,2GNUF@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
gnl|extdb|FAM1414-i1-1.1_000775	754252.PFREUD_09520	1.48e-213	588.0	COG0388@1|root,COG0388@2|Bacteria,2GP6F@201174|Actinobacteria	201174|Actinobacteria	S	Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
gnl|extdb|FAM1414-i1-1.1_000776	754252.PFREUD_09540	0.0	875.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,4DPFZ@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
gnl|extdb|FAM1414-i1-1.1_000777	754252.PFREUD_09550	5.46e-191	530.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4DN5P@85009|Propionibacteriales	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
gnl|extdb|FAM1414-i1-1.1_000739	754252.PFREUD_09160	1.25e-207	577.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4DPI0@85009|Propionibacteriales	201174|Actinobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
gnl|extdb|FAM1414-i1-1.1_000746	754252.PFREUD_09230	8.2e-152	428.0	COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_000750	754252.PFREUD_09270	4.05e-280	764.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DNZA@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
gnl|extdb|FAM1414-i1-1.1_000751	754252.PFREUD_09280	1.74e-266	729.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria	201174|Actinobacteria	F	Deoxyguanosinetriphosphate triphosphohydrolase-like protein	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
gnl|extdb|FAM1414-i1-1.1_000752	754252.PFREUD_09290	2.95e-152	430.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,4DSGT@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0014)	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
gnl|extdb|FAM1414-i1-1.1_000778	1416752.AYME01000003_gene3088	1.29e-107	335.0	COG3206@1|root,COG3206@2|Bacteria,2I35M@201174|Actinobacteria	201174|Actinobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000779	754252.PFREUD_03030	3.86e-194	538.0	2FC2C@1|root,3446A@2|Bacteria,2H4PU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000780	754252.PFREUD_02870	3.7e-118	338.0	COG0783@1|root,COG0783@2|Bacteria,2IFDP@201174|Actinobacteria,4DQZR@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
gnl|extdb|FAM1414-i1-1.1_000781	754252.PFREUD_02850	9.37e-115	338.0	COG1266@1|root,COG1266@2|Bacteria,2IID1@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
gnl|extdb|FAM1414-i1-1.1_000782	1171373.PACID_09790	0.00021	42.7	COG3237@1|root,COG3237@2|Bacteria	2|Bacteria	K	CsbD-like	csbD	-	-	-	-	-	-	-	-	-	-	-	CsbD
gnl|extdb|FAM1414-i1-1.1_000783	754252.PFREUD_02830	1.05e-230	638.0	COG0318@1|root,COG0318@2|Bacteria,2I908@201174|Actinobacteria,4DV3A@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
gnl|extdb|FAM1414-i1-1.1_000784	754252.PFREUD_02820	2.34e-264	725.0	COG0183@1|root,COG0183@2|Bacteria,2GM29@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	yhfS	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
gnl|extdb|FAM1414-i1-1.1_000785	754252.PFREUD_02810	0.0	957.0	COG2271@1|root,COG2271@2|Bacteria,2IE3Y@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator Superfamily	uhpT	-	-	ko:K07784	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.1	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_000786	754252.PFREUD_02800	3.72e-201	557.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	-	-	3.1.22.1,3.1.3.25	ko:K01092,ko:K01158	ko00521,ko00562,ko01100,ko04070,ko04142,map00521,map00562,map01100,map04070,map04142	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GDPD,Inositol_P
gnl|extdb|FAM1414-i1-1.1_000787	754252.PFREUD_02790	0.0	950.0	COG1457@1|root,COG1457@2|Bacteria,2GJ6B@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
gnl|extdb|FAM1414-i1-1.1_000788	754252.PFREUD_02780	1.84e-238	655.0	COG0524@1|root,COG0524@2|Bacteria,2IA3T@201174|Actinobacteria	201174|Actinobacteria	G	Kinase, PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,PfkB
gnl|extdb|FAM1414-i1-1.1_000789	754252.PFREUD_02720	6.21e-98	285.0	COG1051@1|root,COG1051@2|Bacteria,2IQEA@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	mutT2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_000790	1292373.H640_01106	6.89e-228	672.0	COG1100@1|root,COG1100@2|Bacteria,2I8GF@201174|Actinobacteria,4DV8E@85009|Propionibacteriales	201174|Actinobacteria	L	Z1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Z1
gnl|extdb|FAM1414-i1-1.1_000791	66429.JOFL01000011_gene2818	1.7e-16	86.3	2C6HZ@1|root,32RIB@2|Bacteria,2IEAM@201174|Actinobacteria	201174|Actinobacteria	S	Putative  PD-(D/E)XK family member, (DUF4420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4420
gnl|extdb|FAM1414-i1-1.1_000792	1171373.PACID_28370	5.98e-118	370.0	28JJU@1|root,2Z9CS@2|Bacteria,2IFY1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000793	1292373.H640_01091	6.17e-39	145.0	2DBVM@1|root,2ZBBP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000794	1292373.H640_01086	4.33e-43	154.0	2ES8K@1|root,33JT9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000796	794903.OPIT5_28690	9.86e-154	447.0	COG0270@1|root,COG0270@2|Bacteria	2|Bacteria	L	DNA (cytosine-5-)-methyltransferase activity	dcm	GO:0003674,GO:0003824,GO:0003886,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044728,GO:0046483,GO:0071704,GO:0090116,GO:0090304,GO:0140097,GO:1901360	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_3
gnl|extdb|FAM1414-i1-1.1_000798	754252.PFREUD_24640	8.06e-301	819.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GJ3V@201174|Actinobacteria,4DSTQ@85009|Propionibacteriales	201174|Actinobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
gnl|extdb|FAM1414-i1-1.1_000799	754252.PFREUD_02700	0.0	930.0	COG2271@1|root,COG2271@2|Bacteria,2H9HJ@201174|Actinobacteria,4DMYK@85009|Propionibacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	GO:0005575,GO:0005576	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_000800	754252.PFREUD_02670	4.1e-164	460.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
gnl|extdb|FAM1414-i1-1.1_000801	754252.PFREUD_02660	0.0	1071.0	COG1409@1|root,COG1409@2|Bacteria,2GK31@201174|Actinobacteria,4DN1J@85009|Propionibacteriales	201174|Actinobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
gnl|extdb|FAM1414-i1-1.1_000802	754252.PFREUD_02650	0.0	879.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08368	-	-	-	-	ko00000,ko02000	2.A.1	-	-	Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000803	754252.PFREUD_02640	0.0	1505.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
gnl|extdb|FAM1414-i1-1.1_000804	754252.PFREUD_02630	1.8e-152	429.0	COG1309@1|root,COG1309@2|Bacteria,2I8DN@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
gnl|extdb|FAM1414-i1-1.1_000805	754252.PFREUD_02620	1.85e-242	665.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4DP83@85009|Propionibacteriales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	galE1	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
gnl|extdb|FAM1414-i1-1.1_000806	754252.PFREUD_02610	2.68e-316	863.0	COG0471@1|root,COG0471@2|Bacteria,2IEZE@201174|Actinobacteria	201174|Actinobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Na_sulph_symp
gnl|extdb|FAM1414-i1-1.1_000808	754252.PFREUD_02590	1.26e-207	577.0	COG0614@1|root,COG0614@2|Bacteria,2I1A6@201174|Actinobacteria,4DWT6@85009|Propionibacteriales	201174|Actinobacteria	P	Periplasmic binding protein	siuS16	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
gnl|extdb|FAM1414-i1-1.1_000810	754252.PFREUD_02570	2.94e-202	565.0	COG4779@1|root,COG4779@2|Bacteria,2GJ7A@201174|Actinobacteria,4DT74@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
gnl|extdb|FAM1414-i1-1.1_000813	754252.PFREUD_02540	4.45e-308	843.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4DPN1@85009|Propionibacteriales	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
gnl|extdb|FAM1414-i1-1.1_000795	1120934.KB894410_gene6982	2.34e-46	153.0	COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4E51W@85010|Pseudonocardiales	201174|Actinobacteria	L	TIGRFAM DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,Vsr
gnl|extdb|FAM1414-i1-1.1_000807	754252.PFREUD_02600	3.14e-182	507.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4DQCW@85009|Propionibacteriales	201174|Actinobacteria	GK	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
gnl|extdb|FAM1414-i1-1.1_000809	754252.PFREUD_02580	9.48e-208	578.0	COG0609@1|root,COG0609@2|Bacteria,2GJB9@201174|Actinobacteria,4DTAG@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
gnl|extdb|FAM1414-i1-1.1_000811	754252.PFREUD_02560	2.12e-197	548.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria,4DQ2B@85009|Propionibacteriales	201174|Actinobacteria	HP	ATPases associated with a variety of cellular activities	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000812	754252.PFREUD_02550	0.0	1085.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4DNTZ@85009|Propionibacteriales	201174|Actinobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
gnl|extdb|FAM1414-i1-1.1_000815	754252.PFREUD_22490	1.22e-311	849.0	COG2271@1|root,COG2271@2|Bacteria,2GIS1@201174|Actinobacteria,4DUJT@85009|Propionibacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_000816	754252.PFREUD_22480	1.13e-164	461.0	COG1802@1|root,COG1802@2|Bacteria,2IKBV@201174|Actinobacteria,4DVIQ@85009|Propionibacteriales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
gnl|extdb|FAM1414-i1-1.1_000817	754252.PFREUD_22470	0.0	1082.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4DN06@85009|Propionibacteriales	201174|Actinobacteria	G	Dihydroxyacetone kinase	dhaK	GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0030246,GO:0042221,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701	2.7.1.121,2.7.1.209,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878,ko:K20901	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059,R11460	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1,Dak2
gnl|extdb|FAM1414-i1-1.1_000818	754252.PFREUD_22460	1.24e-178	497.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4DP7B@85009|Propionibacteriales	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	-	-	5.1.3.39,5.3.1.1	ko:K01803,ko:K20905	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
gnl|extdb|FAM1414-i1-1.1_000819	754252.PFREUD_22450	1.96e-188	524.0	COG1349@1|root,COG1349@2|Bacteria,2IBBZ@201174|Actinobacteria,4DQU0@85009|Propionibacteriales	201174|Actinobacteria	K	DeoR C terminal sensor domain	sucR	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
gnl|extdb|FAM1414-i1-1.1_000820	754252.PFREUD_22440	7.09e-153	430.0	COG4221@1|root,COG4221@2|Bacteria,2GKK7@201174|Actinobacteria,4DRYB@85009|Propionibacteriales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
gnl|extdb|FAM1414-i1-1.1_000821	754252.PFREUD_22430	4.1e-111	319.0	COG0698@1|root,COG0698@2|Bacteria,2IIDQ@201174|Actinobacteria	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	-	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
gnl|extdb|FAM1414-i1-1.1_000822	754252.PFREUD_22420	5.06e-260	712.0	arCOG04584@1|root,2ZYP7@2|Bacteria,2IBQ6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000823	754252.PFREUD_22410	3.63e-216	595.0	COG0647@1|root,COG0647@2|Bacteria,2IBHB@201174|Actinobacteria,4DQQ5@85009|Propionibacteriales	201174|Actinobacteria	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
gnl|extdb|FAM1414-i1-1.1_000824	754252.PFREUD_22400	0.0	1076.0	COG1069@1|root,COG1069@2|Bacteria,2I41D@201174|Actinobacteria,4DQK0@85009|Propionibacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
gnl|extdb|FAM1414-i1-1.1_000825	754252.PFREUD_22380	0.0	927.0	COG0371@1|root,COG0371@2|Bacteria,2GKWA@201174|Actinobacteria,4DQ5E@85009|Propionibacteriales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
gnl|extdb|FAM1414-i1-1.1_000826	754252.PFREUD_22370	0.0	1040.0	COG1069@1|root,COG1069@2|Bacteria,2H531@201174|Actinobacteria,4DP9J@85009|Propionibacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, C-terminal domain	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
gnl|extdb|FAM1414-i1-1.1_000827	754252.PFREUD_22360	0.0	1366.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4DN1Y@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
gnl|extdb|FAM1414-i1-1.1_000828	754252.PFREUD_22350	9.62e-75	223.0	COG4357@1|root,COG4357@2|Bacteria	2|Bacteria	S	CHY zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHY
gnl|extdb|FAM1414-i1-1.1_000829	754252.PFREUD_22340	0.0	1499.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DTER@85009|Propionibacteriales	201174|Actinobacteria	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_000830	754252.PFREUD_22330	8.24e-217	598.0	COG0676@1|root,COG0676@2|Bacteria,2IIUH@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
gnl|extdb|FAM1414-i1-1.1_000831	754252.PFREUD_22320	3.09e-195	541.0	COG1708@1|root,COG1708@2|Bacteria,2I71C@201174|Actinobacteria	201174|Actinobacteria	L	Domain of unknown function (DUF4111)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4111
gnl|extdb|FAM1414-i1-1.1_000833	396014.BF93_15390	0.000352	50.1	2C23B@1|root,33FM7@2|Bacteria,2GXYA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000834	754252.PFREUD_22290	2.3e-295	806.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4DN29@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
gnl|extdb|FAM1414-i1-1.1_000835	754252.PFREUD_22280	1.15e-194	540.0	COG2120@1|root,COG2120@2|Bacteria,2GKUM@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway	-	-	3.5.1.103	ko:K15525	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
gnl|extdb|FAM1414-i1-1.1_000836	754252.PFREUD_22270	2.99e-124	356.0	COG3247@1|root,COG3247@2|Bacteria,2H3AT@201174|Actinobacteria,4DS50@85009|Propionibacteriales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
gnl|extdb|FAM1414-i1-1.1_000837	754252.PFREUD_22260	3.7e-234	644.0	COG0462@1|root,COG0462@2|Bacteria,2GKR2@201174|Actinobacteria,4DQ3C@85009|Propionibacteriales	201174|Actinobacteria	EF	Phosphoribosyl synthetase-associated domain	prs_1	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
gnl|extdb|FAM1414-i1-1.1_000838	754252.PFREUD_22250	2.23e-166	464.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria	201174|Actinobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,Methyltransf_11
gnl|extdb|FAM1414-i1-1.1_000839	754252.PFREUD_22240	1.63e-260	716.0	COG0477@1|root,COG2814@2|Bacteria,2IAX5@201174|Actinobacteria	201174|Actinobacteria	EGP	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000840	754252.PFREUD_22230	1.26e-73	221.0	COG0789@1|root,COG0789@2|Bacteria,2IIEZ@201174|Actinobacteria,4DRBZ@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1,Redoxin
gnl|extdb|FAM1414-i1-1.1_000842	754252.PFREUD_22210	7.36e-114	326.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
gnl|extdb|FAM1414-i1-1.1_000843	754252.PFREUD_22200	1.29e-76	228.0	COG0640@1|root,COG0640@2|Bacteria,2IMDE@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	cmtR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K21885	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
gnl|extdb|FAM1414-i1-1.1_000844	754252.PFREUD_22190	0.0	1229.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPEN@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	cadA	-	3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54	ko:K01533,ko:K01534,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
gnl|extdb|FAM1414-i1-1.1_000849	754252.PFREUD_22140	1.16e-141	400.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
gnl|extdb|FAM1414-i1-1.1_000850	1121924.ATWH01000008_gene678	1.59e-101	305.0	COG0395@1|root,COG0395@2|Bacteria,2GJ3P@201174|Actinobacteria,4FRNV@85023|Microbacteriaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_000851	883069.HMPREF9238_00890	1.09e-122	360.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D3GB@85005|Actinomycetales	201174|Actinobacteria	P	ABC transporter permease	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_000852	883069.HMPREF9238_00889	6.79e-151	441.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	msmE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
gnl|extdb|FAM1414-i1-1.1_000853	1171373.PACID_03120	3.62e-313	877.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4DSZC@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
gnl|extdb|FAM1414-i1-1.1_000854	1171373.PACID_07290	2.37e-111	333.0	COG1609@1|root,COG1609@2|Bacteria,2GM7M@201174|Actinobacteria,4DWNW@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
gnl|extdb|FAM1414-i1-1.1_000855	754252.PFREUD_22130	8.62e-155	435.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
gnl|extdb|FAM1414-i1-1.1_000847	754252.PFREUD_22160	6.79e-192	532.0	COG0614@1|root,COG0614@2|Bacteria,2GYJE@201174|Actinobacteria,4DPCN@85009|Propionibacteriales	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
gnl|extdb|FAM1414-i1-1.1_000859	754252.PFREUD_00160	0.0	1785.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4DN2Z@85009|Propionibacteriales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
gnl|extdb|FAM1414-i1-1.1_000860	754252.PFREUD_00170	1.03e-208	577.0	2CR6U@1|root,32SNH@2|Bacteria,2IRNY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000861	754252.PFREUD_00180	3.08e-61	187.0	2E7BZ@1|root,331V9@2|Bacteria,2GQHG@201174|Actinobacteria	201174|Actinobacteria	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
gnl|extdb|FAM1414-i1-1.1_000862	754252.PFREUD_00190	4.46e-184	512.0	COG1355@1|root,COG1355@2|Bacteria	2|Bacteria	C	regulation of microtubule-based process	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
gnl|extdb|FAM1414-i1-1.1_000863	754252.PFREUD_00200	8.6e-138	389.0	COG2078@1|root,COG2078@2|Bacteria,2ISCW@201174|Actinobacteria	201174|Actinobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
gnl|extdb|FAM1414-i1-1.1_000864	754252.PFREUD_00210	1.8e-275	751.0	COG1180@1|root,COG1180@2|Bacteria	2|Bacteria	C	glycyl-radical enzyme activating activity	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
gnl|extdb|FAM1414-i1-1.1_000865	754252.PFREUD_00220	7.17e-110	317.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4DR9G@85009|Propionibacteriales	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
gnl|extdb|FAM1414-i1-1.1_000870	1171373.PACID_09350	2.03e-68	222.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
gnl|extdb|FAM1414-i1-1.1_000872	754252.PFREUD_00290	8e-290	795.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
gnl|extdb|FAM1414-i1-1.1_000875	754252.PFREUD_00320	0.0	953.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4DNF6@85009|Propionibacteriales	201174|Actinobacteria	T	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
gnl|extdb|FAM1414-i1-1.1_000876	754252.PFREUD_00330	0.0	870.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	kgtP	-	-	ko:K03761	-	-	-	-	ko00000,ko02000	2.A.1.6.2	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000877	754252.PFREUD_00340	1.96e-293	800.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4DNXZ@85009|Propionibacteriales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
gnl|extdb|FAM1414-i1-1.1_000879	754252.PFREUD_00360	0.0	1025.0	COG1132@1|root,COG1132@2|Bacteria,2GJ8B@201174|Actinobacteria,4DNKK@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_000880	754252.PFREUD_00370	5.26e-259	711.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4DNSB@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
gnl|extdb|FAM1414-i1-1.1_000881	754252.PFREUD_00380	0.0	983.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	cycA	-	-	ko:K03293,ko:K11737	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.7	-	-	AA_permease
gnl|extdb|FAM1414-i1-1.1_000882	754252.PFREUD_00390	1.8e-275	754.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,4DN7Y@85009|Propionibacteriales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	lppS	-	-	-	-	-	-	-	-	-	-	-	YkuD
gnl|extdb|FAM1414-i1-1.1_000883	754252.PFREUD_00400	1.14e-58	181.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
gnl|extdb|FAM1414-i1-1.1_000884	1122130.AUHN01000005_gene2443	1.21e-40	135.0	COG2026@1|root,COG2026@2|Bacteria,2IRES@201174|Actinobacteria	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
gnl|extdb|FAM1414-i1-1.1_000885	1348338.ADILRU_2309	1.65e-37	128.0	COG2161@1|root,COG2161@2|Bacteria,2GSF2@201174|Actinobacteria,4FPZ6@85023|Microbacteriaceae	201174|Actinobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
gnl|extdb|FAM1414-i1-1.1_000887	754252.PFREUD_00420	2.4e-102	298.0	COG0778@1|root,COG0778@2|Bacteria,2IHY1@201174|Actinobacteria,4DU3G@85009|Propionibacteriales	201174|Actinobacteria	C	Nitroreductase family	tdsD	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
gnl|extdb|FAM1414-i1-1.1_000888	1120954.ATXE01000002_gene1228	5.26e-70	233.0	COG2244@1|root,COG2244@2|Bacteria,2I8M1@201174|Actinobacteria	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000889	234621.RER_02460	1.79e-95	289.0	COG1215@1|root,COG1215@2|Bacteria,2I3WV@201174|Actinobacteria,4G8KF@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
gnl|extdb|FAM1414-i1-1.1_000890	1120954.ATXE01000002_gene1230	2.21e-81	256.0	COG0451@1|root,COG0451@2|Bacteria,2IISR@201174|Actinobacteria,4DQVX@85009|Propionibacteriales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
gnl|extdb|FAM1414-i1-1.1_000891	1120954.ATXE01000002_gene1231	1.45e-146	424.0	COG0463@1|root,COG0463@2|Bacteria,2I3C0@201174|Actinobacteria,4DNR6@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	wcqE	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
gnl|extdb|FAM1414-i1-1.1_000892	754252.PFREUD_00470	1.63e-198	551.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4DNRQ@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0334	NTP_transferase
gnl|extdb|FAM1414-i1-1.1_000893	754252.PFREUD_00480	5.32e-167	468.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4DWXT@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
gnl|extdb|FAM1414-i1-1.1_000894	754252.PFREUD_00490	4.69e-59	186.0	COG2456@1|root,COG2456@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	XK27_09090	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
gnl|extdb|FAM1414-i1-1.1_000896	754252.PFREUD_00510	2.27e-222	622.0	COG2244@1|root,COG2244@2|Bacteria,2I9WN@201174|Actinobacteria	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	-
gnl|extdb|FAM1414-i1-1.1_000858	754252.PFREUD_00150	0.0	1317.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4DN1A@85009|Propionibacteriales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
gnl|extdb|FAM1414-i1-1.1_000873	754252.PFREUD_00300	0.0	1061.0	COG0477@1|root,COG2814@2|Bacteria,2H1X6@201174|Actinobacteria	201174|Actinobacteria	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
gnl|extdb|FAM1414-i1-1.1_000874	754252.PFREUD_00310	1.04e-144	409.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
gnl|extdb|FAM1414-i1-1.1_000878	754252.PFREUD_00350	0.0	985.0	COG1132@1|root,COG1132@2|Bacteria,2GJAP@201174|Actinobacteria,4DQK3@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
gnl|extdb|FAM1414-i1-1.1_000886	754252.PFREUD_00410	4.74e-123	354.0	COG1739@1|root,COG1739@2|Bacteria,2GMM4@201174|Actinobacteria,4DQWQ@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized protein family UPF0029	yigZ	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
gnl|extdb|FAM1414-i1-1.1_000897	754252.PFREUD_03310	6.41e-109	351.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Polysacc_deac_1,SLH,VCBS
gnl|extdb|FAM1414-i1-1.1_000898	754252.PFREUD_03300	1.67e-142	403.0	COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4DQ48@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_000899	754252.PFREUD_03290	1.81e-291	797.0	COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4DPWT@85009|Propionibacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
gnl|extdb|FAM1414-i1-1.1_000900	754252.PFREUD_03280	6.39e-212	587.0	COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4DPJ9@85009|Propionibacteriales	201174|Actinobacteria	P	NLPA lipoprotein	-	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
gnl|extdb|FAM1414-i1-1.1_000901	754252.PFREUD_03270	2.8e-171	478.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DNE1@85009|Propionibacteriales	201174|Actinobacteria	T	response regulator	tcrX	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
gnl|extdb|FAM1414-i1-1.1_000902	754252.PFREUD_03260	0.0	1142.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4DNGB@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
gnl|extdb|FAM1414-i1-1.1_000903	754252.PFREUD_03250	2.31e-214	594.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
gnl|extdb|FAM1414-i1-1.1_000904	754252.PFREUD_03240	0.0	1461.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA
gnl|extdb|FAM1414-i1-1.1_000905	754252.PFREUD_03230	0.0	1702.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4DPDB@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
gnl|extdb|FAM1414-i1-1.1_000906	754252.PFREUD_03210	1.36e-210	582.0	COG1806@1|root,COG1806@2|Bacteria,2IDD1@201174|Actinobacteria	201174|Actinobacteria	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
gnl|extdb|FAM1414-i1-1.1_000908	754252.PFREUD_03180	5.77e-244	669.0	COG2813@1|root,COG2813@2|Bacteria,2I8VY@201174|Actinobacteria	201174|Actinobacteria	J	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA	rlmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.172,2.1.1.174	ko:K00564,ko:K11391	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
gnl|extdb|FAM1414-i1-1.1_000909	754252.PFREUD_03170	1.89e-181	505.0	28NT3@1|root,2ZBRV@2|Bacteria,2IIC3@201174|Actinobacteria,4DW8G@85009|Propionibacteriales	201174|Actinobacteria	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
gnl|extdb|FAM1414-i1-1.1_000910	754252.PFREUD_03160	4.55e-207	572.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4DN3W@85009|Propionibacteriales	201174|Actinobacteria	S	Aldo/keto reductase family	dkgA	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
gnl|extdb|FAM1414-i1-1.1_000911	479434.Sthe_0222	6.75e-05	49.7	COG4194@1|root,COG4194@2|Bacteria,2G921@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
gnl|extdb|FAM1414-i1-1.1_000912	754252.PFREUD_03140	2.55e-84	256.0	COG1335@1|root,COG1335@2|Bacteria,2GKZR@201174|Actinobacteria,4DSEZ@85009|Propionibacteriales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
gnl|extdb|FAM1414-i1-1.1_000914	754252.PFREUD_03120	1.72e-288	787.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4DRPN@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
gnl|extdb|FAM1414-i1-1.1_000915	754252.PFREUD_03110	0.0	1018.0	COG0427@1|root,COG0427@2|Bacteria,2I9EB@201174|Actinobacteria,4DPYR@85009|Propionibacteriales	201174|Actinobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	cat1	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
gnl|extdb|FAM1414-i1-1.1_000916	754252.PFREUD_03100	1.68e-186	519.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4DR4D@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.127,1.1.1.69	ko:K00046,ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
gnl|extdb|FAM1414-i1-1.1_000917	754252.PFREUD_03090	1.96e-252	692.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4DRRR@85009|Propionibacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
gnl|extdb|FAM1414-i1-1.1_000918	754252.PFREUD_03080	1.34e-152	429.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	ppaX	-	3.1.3.105,3.1.3.18,3.6.1.1	ko:K01091,ko:K06019,ko:K16017,ko:K22292	ko00190,ko00520,ko00630,ko01051,ko01100,ko01110,ko01130,map00190,map00520,map00630,map01051,map01100,map01110,map01130	-	R01334,R06587,R11785	RC00017,RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
gnl|extdb|FAM1414-i1-1.1_000919	754252.PFREUD_03070	0.0	1069.0	28MCF@1|root,2ZAQK@2|Bacteria,2IDHH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000920	1035308.AQYY01000001_gene1494	1.03e-13	75.9	2DEXG@1|root,2ZPNB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000922	1410674.JNKU01000056_gene1899	2.03e-23	100.0	2BJ3M@1|root,32DCI@2|Bacteria,1TUND@1239|Firmicutes,4HYB7@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_000924	1074488.AGBX01000007_gene1502	4.91e-19	81.3	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4FCZ7@85020|Dermabacteraceae	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_000907	754252.PFREUD_03190	3.6e-274	755.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4DPMZ@85009|Propionibacteriales	201174|Actinobacteria	V	MatE	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
gnl|extdb|FAM1414-i1-1.1_000913	754252.PFREUD_03130	3.99e-284	779.0	COG0671@1|root,COG0671@2|Bacteria,2HISK@201174|Actinobacteria	201174|Actinobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
gnl|extdb|FAM1414-i1-1.1_001173	378753.KRH_07440	1.25e-17	77.0	COG1396@1|root,COG1396@2|Bacteria,2HWH4@201174|Actinobacteria,1WA91@1268|Micrococcaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
gnl|extdb|FAM1414-i1-1.1_001174	754252.PFREUD_16680	1.44e-148	419.0	COG1954@1|root,COG1954@2|Bacteria	2|Bacteria	K	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
gnl|extdb|FAM1414-i1-1.1_001175	754252.PFREUD_16670	0.0	1036.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4DNGC@85009|Propionibacteriales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
gnl|extdb|FAM1414-i1-1.1_001176	1197706.AKKK01000011_gene420	1.25e-218	624.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,1W7WK@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
gnl|extdb|FAM1414-i1-1.1_001177	754252.PFREUD_16610	7.08e-228	630.0	COG0798@1|root,COG0798@2|Bacteria,2GIZD@201174|Actinobacteria,4DQFJ@85009|Propionibacteriales	201174|Actinobacteria	P	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF,SBF_like
gnl|extdb|FAM1414-i1-1.1_001178	754252.PFREUD_16600	1.71e-263	723.0	COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria	201174|Actinobacteria	P	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
gnl|extdb|FAM1414-i1-1.1_001179	469371.Tbis_1596	3.58e-05	43.5	2DF5H@1|root,2ZQJB@2|Bacteria,2GX57@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001180	754252.PFREUD_16580	1.76e-147	416.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4DVRE@85009|Propionibacteriales	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
gnl|extdb|FAM1414-i1-1.1_001181	754252.PFREUD_16570	5.47e-298	813.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,4DR72@85009|Propionibacteriales	201174|Actinobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
gnl|extdb|FAM1414-i1-1.1_001182	754252.PFREUD_16560	5.91e-46	148.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154,ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
gnl|extdb|FAM1414-i1-1.1_001183	754252.PFREUD_16550	8.55e-183	510.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4DP6Q@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0008150,GO:0040007	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
gnl|extdb|FAM1414-i1-1.1_001184	754252.PFREUD_16540	3.17e-278	763.0	COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,4DNCG@85009|Propionibacteriales	201174|Actinobacteria	H	ThiF family	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
gnl|extdb|FAM1414-i1-1.1_001185	754252.PFREUD_16530	3.33e-229	634.0	COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria,4DQTV@85009|Propionibacteriales	201174|Actinobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
gnl|extdb|FAM1414-i1-1.1_001186	754252.PFREUD_16520	5.74e-212	586.0	COG0583@1|root,COG0583@2|Bacteria,2I8WJ@201174|Actinobacteria,4DT8E@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
gnl|extdb|FAM1414-i1-1.1_001187	754252.PFREUD_16510	1.45e-50	159.0	COG2879@1|root,COG2879@2|Bacteria,2GQWY@201174|Actinobacteria	201174|Actinobacteria	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
gnl|extdb|FAM1414-i1-1.1_001188	754252.PFREUD_16500	0.0	1519.0	COG1966@1|root,COG1966@2|Bacteria,2GIYX@201174|Actinobacteria,4DN9Z@85009|Propionibacteriales	201174|Actinobacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
gnl|extdb|FAM1414-i1-1.1_001189	754252.PFREUD_16490	9.64e-251	690.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	garK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
gnl|extdb|FAM1414-i1-1.1_001191	754252.PFREUD_16470	5.42e-226	621.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	ubiG	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
gnl|extdb|FAM1414-i1-1.1_001193	754252.PFREUD_16450	6.35e-201	558.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DNRX@85009|Propionibacteriales	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	proX	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
gnl|extdb|FAM1414-i1-1.1_001194	754252.PFREUD_16440	9.3e-212	591.0	COG2807@1|root,COG2807@2|Bacteria,2GP5W@201174|Actinobacteria,4DQR2@85009|Propionibacteriales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_001195	1713.JOFV01000003_gene1575	9.15e-24	92.8	COG4877@1|root,COG4877@2|Bacteria,2GQV1@201174|Actinobacteria,4F2ZW@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001196	754252.PFREUD_16430	6.46e-217	600.0	COG0330@1|root,COG0330@2|Bacteria,2GM0Z@201174|Actinobacteria,4DTH0@85009|Propionibacteriales	201174|Actinobacteria	O	prohibitin homologues	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
gnl|extdb|FAM1414-i1-1.1_001197	754252.PFREUD_16420	5.63e-227	625.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
gnl|extdb|FAM1414-i1-1.1_001198	754252.PFREUD_16410	4.98e-250	686.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
gnl|extdb|FAM1414-i1-1.1_001199	1122994.AUFR01000032_gene510	2.76e-47	172.0	2DXWE@1|root,346YS@2|Bacteria,2H8B6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001201	754252.PFREUD_16380	1.79e-117	336.0	COG2236@1|root,COG2236@2|Bacteria,2GN86@201174|Actinobacteria,4DRPW@85009|Propionibacteriales	201174|Actinobacteria	F	Phosphoribosyl transferase domain	gpt	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
gnl|extdb|FAM1414-i1-1.1_001203	754252.PFREUD_16360	1.23e-119	342.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
gnl|extdb|FAM1414-i1-1.1_001204	754252.PFREUD_16350	5.42e-310	846.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4DNW0@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	pimH	-	-	-	-	-	-	-	-	-	-	-	MFS_3
gnl|extdb|FAM1414-i1-1.1_001205	754252.PFREUD_16340	1.12e-288	791.0	COG2704@1|root,COG2704@2|Bacteria,2GKYB@201174|Actinobacteria	201174|Actinobacteria	S	Anaerobic c4-dicarboxylate	-	-	-	ko:K07791	-	-	-	-	ko00000,ko02000	2.A.13.1	-	-	DcuA_DcuB
gnl|extdb|FAM1414-i1-1.1_001206	754252.PFREUD_24680	3.1e-118	345.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DUKR@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve,rve_3
gnl|extdb|FAM1414-i1-1.1_001190	754252.PFREUD_16480	0.0	973.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DTQ6@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_001192	754252.PFREUD_16460	2.2e-158	444.0	COG1990@1|root,COG1990@2|Bacteria,2HEY8@201174|Actinobacteria,4DRVA@85009|Propionibacteriales	201174|Actinobacteria	S	Peptidyl-tRNA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PTH2
gnl|extdb|FAM1414-i1-1.1_001200	754252.PFREUD_16390	6.41e-281	769.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria	201174|Actinobacteria	M	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
gnl|extdb|FAM1414-i1-1.1_001202	754252.PFREUD_16370	1.06e-111	321.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,4DS6A@85009|Propionibacteriales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
gnl|extdb|FAM1414-i1-1.1_001207	754252.PFREUD_13390	4.79e-250	686.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4DNFA@85009|Propionibacteriales	201174|Actinobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
gnl|extdb|FAM1414-i1-1.1_001208	754252.PFREUD_13400	1.42e-109	316.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4DQCD@85009|Propionibacteriales	201174|Actinobacteria	E	Acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
gnl|extdb|FAM1414-i1-1.1_001209	754252.PFREUD_13410	0.0	1178.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4DNJX@85009|Propionibacteriales	201174|Actinobacteria	E	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
gnl|extdb|FAM1414-i1-1.1_001210	1123023.JIAI01000020_gene2146	4.82e-07	60.1	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4E2EW@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
gnl|extdb|FAM1414-i1-1.1_001211	754252.PFREUD_13430	1.68e-178	497.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4DPEF@85009|Propionibacteriales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
gnl|extdb|FAM1414-i1-1.1_001212	754252.PFREUD_13440	5.15e-247	677.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4DN73@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
gnl|extdb|FAM1414-i1-1.1_001213	754252.PFREUD_13450	8e-79	233.0	COG1359@1|root,COG1359@2|Bacteria,2IQ6Y@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
gnl|extdb|FAM1414-i1-1.1_001215	754252.PFREUD_13470	3.57e-200	555.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
gnl|extdb|FAM1414-i1-1.1_001216	754252.PFREUD_13490	6.59e-195	544.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4DPPK@85009|Propionibacteriales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
gnl|extdb|FAM1414-i1-1.1_001218	1120954.ATXE01000002_gene693	1.1e-16	75.9	COG1826@1|root,COG1826@2|Bacteria,2HZG4@201174|Actinobacteria,4DSNW@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
gnl|extdb|FAM1414-i1-1.1_001219	754252.PFREUD_13530	1.05e-225	622.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4DP7N@85009|Propionibacteriales	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
gnl|extdb|FAM1414-i1-1.1_001220	754252.PFREUD_13540	5.17e-223	615.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4DNBD@85009|Propionibacteriales	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
gnl|extdb|FAM1414-i1-1.1_001221	754252.PFREUD_13550	1.39e-230	634.0	COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
gnl|extdb|FAM1414-i1-1.1_001222	754252.PFREUD_13560	6.19e-226	625.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4DRPD@85009|Propionibacteriales	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkbB	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
gnl|extdb|FAM1414-i1-1.1_001226	754252.PFREUD_13600	1.03e-211	586.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4DMYR@85009|Propionibacteriales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
gnl|extdb|FAM1414-i1-1.1_001227	1032480.MLP_17520	9.43e-21	87.0	2E3JK@1|root,32YHZ@2|Bacteria,2GS0Y@201174|Actinobacteria,4DS71@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001228	754252.PFREUD_13620	1.35e-206	572.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DP0V@85009|Propionibacteriales	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
gnl|extdb|FAM1414-i1-1.1_001230	754252.PFREUD_13640	2.23e-157	441.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4DR6U@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
gnl|extdb|FAM1414-i1-1.1_001231	754252.PFREUD_13650	0.0	1154.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4DP71@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
gnl|extdb|FAM1414-i1-1.1_001232	754252.PFREUD_13660	0.0	967.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4DN95@85009|Propionibacteriales	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
gnl|extdb|FAM1414-i1-1.1_001233	754252.PFREUD_13670	4.62e-223	614.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4DPDG@85009|Propionibacteriales	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
gnl|extdb|FAM1414-i1-1.1_001235	754252.PFREUD_13690	2e-127	363.0	COG0619@1|root,COG0619@2|Bacteria,2IQMQ@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type cobalt transport system permease component CbiQ	-	-	-	ko:K16783	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25.1	-	-	CbiQ
gnl|extdb|FAM1414-i1-1.1_001236	754252.PFREUD_13710	8.26e-164	459.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4DQ9U@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	bioM	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
gnl|extdb|FAM1414-i1-1.1_001237	754252.PFREUD_13720	2.84e-125	359.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4DRM2@85009|Propionibacteriales	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
gnl|extdb|FAM1414-i1-1.1_001238	754252.PFREUD_13730	5.83e-251	688.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4DPB1@85009|Propionibacteriales	201174|Actinobacteria	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
gnl|extdb|FAM1414-i1-1.1_001239	754252.PFREUD_13740	2.37e-201	562.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4DNAU@85009|Propionibacteriales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
gnl|extdb|FAM1414-i1-1.1_001214	754252.PFREUD_13460	0.0	1770.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4DN1B@85009|Propionibacteriales	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
gnl|extdb|FAM1414-i1-1.1_001217	754252.PFREUD_13510	5.87e-170	477.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4DQFM@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
gnl|extdb|FAM1414-i1-1.1_001223	754252.PFREUD_13570	6.96e-117	338.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	fkbB	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
gnl|extdb|FAM1414-i1-1.1_001224	754252.PFREUD_13580	2.04e-182	508.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DNT7@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
gnl|extdb|FAM1414-i1-1.1_001225	754252.PFREUD_13590	3.78e-147	416.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4DQ4Q@85009|Propionibacteriales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
gnl|extdb|FAM1414-i1-1.1_001229	754252.PFREUD_13630	1.73e-206	573.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DNSC@85009|Propionibacteriales	201174|Actinobacteria	L	tyrosine recombinase	xerD	GO:0008150,GO:0040007	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
gnl|extdb|FAM1414-i1-1.1_001245	1122998.AUHZ01000024_gene1327	4.94e-280	848.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DTQE@85009|Propionibacteriales	201174|Actinobacteria	L	DNA primase catalytic core, N-terminal domain	traA	-	-	-	-	-	-	-	-	-	-	-	AAA_30,Toprim_2,Toprim_N,TrwC
gnl|extdb|FAM1414-i1-1.1_001247	767029.HMPREF9154_2258	6.33e-100	322.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria,4DNM4@85009|Propionibacteriales	201174|Actinobacteria	U	Type IV secretory pathway VirD4	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C
gnl|extdb|FAM1414-i1-1.1_001249	882082.SaccyDRAFT_0375	5.35e-07	60.1	COG0455@1|root,COG0455@2|Bacteria,2GMK0@201174|Actinobacteria,4DXEP@85010|Pseudonocardiales	201174|Actinobacteria	D	ATPase involved in chromosome	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
gnl|extdb|FAM1414-i1-1.1_001252	281090.Lxx07680	1.43e-257	742.0	COG3451@1|root,COG3451@2|Bacteria,2H6W2@201174|Actinobacteria	201174|Actinobacteria	U	type IV secretory pathway VirB4	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
gnl|extdb|FAM1414-i1-1.1_001253	1437608.BBIA_1554	9.73e-15	73.6	2DFZH@1|root,2ZTUZ@2|Bacteria,2GTBP@201174|Actinobacteria	201174|Actinobacteria	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
gnl|extdb|FAM1414-i1-1.1_001254	644284.Arch_1692	1.26e-29	120.0	2B0U3@1|root,31T6M@2|Bacteria,2IDXF@201174|Actinobacteria,4D5Z5@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
gnl|extdb|FAM1414-i1-1.1_001255	326426.Bbr_1527	2.66e-27	100.0	2EJJI@1|root,33DAG@2|Bacteria,2GW42@201174|Actinobacteria,4D1C7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001256	754252.PFREUD_03810	5e-40	144.0	COG3764@1|root,COG3764@2|Bacteria,2HF6P@201174|Actinobacteria,4DWEQ@85009|Propionibacteriales	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
gnl|extdb|FAM1414-i1-1.1_001257	1121353.H924_01070	0.000757	51.2	COG4932@1|root,COG4932@2|Bacteria,2HF9J@201174|Actinobacteria,22PH8@1653|Corynebacteriaceae	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001258	33876.JNXY01000023_gene5178	0.000765	46.2	COG1940@1|root,COG1940@2|Bacteria,2GNFJ@201174|Actinobacteria,4D9Z1@85008|Micromonosporales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,MarR_2,ROK
gnl|extdb|FAM1414-i1-1.1_001259	935839.JAGJ01000003_gene1442	0.000106	47.4	COG2856@1|root,COG2856@2|Bacteria,2GY08@201174|Actinobacteria	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
gnl|extdb|FAM1414-i1-1.1_001261	1151119.KB895493_gene1382	1.03e-06	54.3	COG0671@1|root,COG0671@2|Bacteria,2I92V@201174|Actinobacteria,1WA4Q@1268|Micrococcaceae	201174|Actinobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
gnl|extdb|FAM1414-i1-1.1_001263	653386.HMPREF0975_02734	3.23e-51	170.0	COG1192@1|root,COG1192@2|Bacteria,2ICWE@201174|Actinobacteria	201174|Actinobacteria	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
gnl|extdb|FAM1414-i1-1.1_001265	452662.SJA_C1-05500	2.33e-53	176.0	COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,2U9WZ@28211|Alphaproteobacteria,2K0NF@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA invertase	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
gnl|extdb|FAM1414-i1-1.1_001266	562973.HMPREF0059_00697	2.9e-30	111.0	COG4683@1|root,COG4683@2|Bacteria,2IFY3@201174|Actinobacteria,4D6DP@85005|Actinomycetales	201174|Actinobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
gnl|extdb|FAM1414-i1-1.1_001272	445975.COLSTE_02318	2.08e-23	100.0	COG0792@1|root,COG0792@2|Bacteria,2HUX4@201174|Actinobacteria,4CVXC@84998|Coriobacteriia	84998|Coriobacteriia	L	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001273	1150599.MPHLEI_19984	8.96e-07	51.6	29RHX@1|root,30CKW@2|Bacteria,2HB0P@201174|Actinobacteria,23EGS@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001243	1125718.HMPREF1318_2354	2.34e-13	70.1	2BWS4@1|root,32XQ0@2|Bacteria,2GR3P@201174|Actinobacteria,4D7SW@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001251	435830.HMPREF0045_01291	5.01e-42	154.0	COG3583@1|root,COG3942@1|root,COG3583@2|Bacteria,COG3942@2|Bacteria,2I2GH@201174|Actinobacteria	201174|Actinobacteria	M	G5 domain protein	-	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,SLT
gnl|extdb|FAM1414-i1-1.1_001267	521393.JH806632_gene223	5.79e-13	66.2	COG1813@1|root,COG1813@2|Bacteria,2HH2F@201174|Actinobacteria,4D6M0@85005|Actinomycetales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
gnl|extdb|FAM1414-i1-1.1_001277	754252.PFREUD_03870	1.35e-237	653.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
gnl|extdb|FAM1414-i1-1.1_001278	754252.PFREUD_03880	1.44e-292	800.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4DN2D@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the aspartokinase family	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
gnl|extdb|FAM1414-i1-1.1_001279	754252.PFREUD_03890	0.0	1196.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4DNJI@85009|Propionibacteriales	201174|Actinobacteria	KLT	MviN-like protein	mviN	GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
gnl|extdb|FAM1414-i1-1.1_001280	754252.PFREUD_03900	0.0	1251.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
gnl|extdb|FAM1414-i1-1.1_001281	1386089.N865_21015	1.33e-06	52.8	2D6K8@1|root,32TMG@2|Bacteria,2GR9V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001282	754252.PFREUD_03920	7.72e-229	630.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4DQSX@85009|Propionibacteriales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
gnl|extdb|FAM1414-i1-1.1_001284	754252.PFREUD_03940	0.0	1066.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4DQV2@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
gnl|extdb|FAM1414-i1-1.1_001288	754252.PFREUD_03990	0.0	991.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,2GKDW@201174|Actinobacteria	201174|Actinobacteria	P	TrkA C-terminal domain protein	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
gnl|extdb|FAM1414-i1-1.1_001290	754252.PFREUD_04010	0.0	922.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4DNYZ@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
gnl|extdb|FAM1414-i1-1.1_001291	754252.PFREUD_04020	3.88e-264	723.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
gnl|extdb|FAM1414-i1-1.1_001292	754252.PFREUD_04030	2.1e-216	596.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4DP92@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N,SAICAR_synt
gnl|extdb|FAM1414-i1-1.1_001293	754252.PFREUD_04040	4.9e-49	156.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4DS4C@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
gnl|extdb|FAM1414-i1-1.1_001294	754252.PFREUD_04050	1.91e-165	462.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4DNEU@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
gnl|extdb|FAM1414-i1-1.1_001295	754252.PFREUD_04060	9.54e-91	273.0	COG3064@1|root,COG3064@2|Bacteria,2IJCG@201174|Actinobacteria	201174|Actinobacteria	M	Host cell surface-exposed lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp
gnl|extdb|FAM1414-i1-1.1_001296	754252.PFREUD_04070	1.19e-297	813.0	COG0477@1|root,COG2814@2|Bacteria,2GPRH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator	csbX	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_001297	754252.PFREUD_04080	1.09e-147	424.0	2E461@1|root,32Z21@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CD20
gnl|extdb|FAM1414-i1-1.1_001298	1122994.AUFR01000005_gene839	9.99e-06	53.9	COG0515@1|root,COG0515@2|Bacteria,2GY2S@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001276	754252.PFREUD_03860	0.0	2149.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4DNYP@85009|Propionibacteriales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
gnl|extdb|FAM1414-i1-1.1_001283	754252.PFREUD_03930	0.0	923.0	COG0531@1|root,COG0531@2|Bacteria,2HMMA@201174|Actinobacteria,4DNUW@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
gnl|extdb|FAM1414-i1-1.1_001289	754252.PFREUD_04000	7.02e-296	809.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4DN4W@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
gnl|extdb|FAM1414-i1-1.1_001301	1105029.HMPREF1137_0417	5.73e-06	48.9	COG1192@1|root,COG1192@2|Bacteria,2IIMA@201174|Actinobacteria,4D5XA@85005|Actinomycetales	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
gnl|extdb|FAM1414-i1-1.1_001302	861360.AARI_pI00030	3.64e-46	153.0	2B9TB@1|root,32366@2|Bacteria,2H7S2@201174|Actinobacteria,1WBYP@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001303	593907.Celgi_2793	1.98e-56	180.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
gnl|extdb|FAM1414-i1-1.1_001304	754252.PFREUD_21260	7.92e-56	177.0	2EMV9@1|root,33FHI@2|Bacteria,2GZNR@201174|Actinobacteria	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001305	1120946.AUBF01000012_gene1155	1.77e-26	98.2	2DEMJ@1|root,2ZNGD@2|Bacteria,2GZR5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001306	1120946.AUBF01000012_gene1156	1.2e-140	401.0	COG2184@1|root,COG2184@2|Bacteria,2IN0D@201174|Actinobacteria,4D57Z@85005|Actinomycetales	201174|Actinobacteria	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
gnl|extdb|FAM1414-i1-1.1_001308	205869.Q857N5_9CAUD	5.84e-06	49.3	4QDKP@10239|Viruses,4QZHT@35237|dsDNA viruses  no RNA stage,4QTRD@28883|Caudovirales	28883|Caudovirales	S	transaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001309	861360.AARI_06780	5.03e-92	275.0	COG1961@1|root,COG1961@2|Bacteria,2IJUP@201174|Actinobacteria	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Resolvase
gnl|extdb|FAM1414-i1-1.1_001311	861360.AARI_06800	3.67e-65	201.0	28X5X@1|root,2ZJ4C@2|Bacteria	2|Bacteria	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
gnl|extdb|FAM1414-i1-1.1_001312	861360.AARI_06810	0.0	886.0	COG0323@1|root,COG0323@2|Bacteria,2GPWU@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Relaxase mobilization nuclease family protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
gnl|extdb|FAM1414-i1-1.1_001313	861360.AARI_06820	2.91e-103	309.0	2C57Z@1|root,2ZFQ7@2|Bacteria,2GYPW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001314	861360.AARI_06860	1.78e-69	217.0	2E3KC@1|root,32YIM@2|Bacteria,2GQQS@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4913)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4913
gnl|extdb|FAM1414-i1-1.1_001315	861360.AARI_pI00250	0.0	998.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria,1W9JR@1268|Micrococcaceae	201174|Actinobacteria	U	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C
gnl|extdb|FAM1414-i1-1.1_001317	861360.AARI_pI00270	1.91e-307	844.0	28IPW@1|root,2Z8PQ@2|Bacteria,2HQJM@201174|Actinobacteria,1W9EN@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001318	861360.AARI_pI00280	1.17e-208	599.0	2D2AG@1|root,32TCD@2|Bacteria,2IARE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001319	861360.AARI_pI00290	5.14e-73	229.0	2DRVP@1|root,33D9Z@2|Bacteria,2IGDJ@201174|Actinobacteria,1WC2D@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001320	861360.AARI_pI00300	3.81e-46	150.0	2EKRJ@1|root,33EFB@2|Bacteria,2GTVU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001322	1177594.MIC448_50014	1.29e-08	53.9	COG3311@1|root,COG3311@2|Bacteria,2GRPS@201174|Actinobacteria,4FQAK@85023|Microbacteriaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
gnl|extdb|FAM1414-i1-1.1_001323	861360.AARI_pI00340	7.89e-55	178.0	299PB@1|root,2ZWRN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001324	935839.JAGJ01000019_gene2256	1.47e-180	509.0	COG0739@1|root,COG3942@1|root,COG0739@2|Bacteria,COG3942@2|Bacteria,2IQ9S@201174|Actinobacteria	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Peptidase_M23
gnl|extdb|FAM1414-i1-1.1_001325	861360.AARI_pI00360	2.05e-245	684.0	COG0455@1|root,COG0455@2|Bacteria,2GMK0@201174|Actinobacteria	201174|Actinobacteria	D	Involved in chromosome	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
gnl|extdb|FAM1414-i1-1.1_001326	1122238.AULR01000010_gene210	7.76e-07	51.2	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD
gnl|extdb|FAM1414-i1-1.1_001328	861360.AARI_pI00390	6.73e-305	850.0	COG1846@1|root,COG1846@2|Bacteria,2IIX2@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001329	861360.AARI_pI00400	7.85e-156	443.0	COG4227@1|root,COG4227@2|Bacteria,2I2PD@201174|Actinobacteria	201174|Actinobacteria	L	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738,Peptidase_M78
gnl|extdb|FAM1414-i1-1.1_001334	861360.AARI_pI00010	4.06e-58	182.0	2F71V@1|root,33ZHG@2|Bacteria,2H77X@201174|Actinobacteria	201174|Actinobacteria	S	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
gnl|extdb|FAM1414-i1-1.1_001335	1403948.Q618_VCMC00003G0128	3.99e-89	271.0	COG1192@1|root,COG1192@2|Bacteria,2IIMA@201174|Actinobacteria,4D5XA@85005|Actinomycetales	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
gnl|extdb|FAM1414-i1-1.1_001316	861360.AARI_pI00260	0.0	928.0	COG0433@1|root,COG0433@2|Bacteria,2I70J@201174|Actinobacteria,1W9A2@1268|Micrococcaceae	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
gnl|extdb|FAM1414-i1-1.1_001331	861360.AARI_pI00440	2.78e-39	132.0	COG0695@1|root,COG0695@2|Bacteria,2H960@201174|Actinobacteria,1WBYC@1268|Micrococcaceae	201174|Actinobacteria	O	Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
gnl|extdb|FAM1414-i1-1.1_001321	1246474.ANBE01000003_gene2020	3.49e-67	211.0	2CS83@1|root,32SQM@2|Bacteria,2IRK9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001336	1122997.AUDD01000010_gene800	1.1e-25	96.7	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DUKR@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve,rve_3
gnl|extdb|FAM1414-i1-1.1_001337	754252.PFREUD_02390	1.27e-212	589.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria,4DNGK@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator, RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
gnl|extdb|FAM1414-i1-1.1_001338	754252.PFREUD_02370	0.0	2136.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4DPD7@85009|Propionibacteriales	201174|Actinobacteria	G	Beta galactosidase small chain	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
gnl|extdb|FAM1414-i1-1.1_001339	754252.PFREUD_02360	0.0	888.0	COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
gnl|extdb|FAM1414-i1-1.1_001340	1122998.AUHZ01000019_gene1684	3.9e-243	667.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4DP83@85009|Propionibacteriales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	galE1	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
gnl|extdb|FAM1414-i1-1.1_001341	754252.PFREUD_24450	0.0	872.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001343	465515.Mlut_00380	2.91e-201	566.0	2EZ4D@1|root,33SAM@2|Bacteria,2GSWH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001344	1032480.MLP_37790	3.23e-172	516.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DPHY@85009|Propionibacteriales	201174|Actinobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
gnl|extdb|FAM1414-i1-1.1_001345	1429046.RR21198_1502	8.3e-203	592.0	COG3593@1|root,COG3593@2|Bacteria,2ICNW@201174|Actinobacteria	201174|Actinobacteria	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
gnl|extdb|FAM1414-i1-1.1_001347	478801.Ksed_08050	3.5e-140	432.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
gnl|extdb|FAM1414-i1-1.1_001349	1122998.AUHZ01000004_gene1125	1.39e-91	275.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	rarD	-	-	-	-	-	-	-	-	-	-	-	EamA
gnl|extdb|FAM1414-i1-1.1_001350	1122998.AUHZ01000004_gene1125	3.58e-47	159.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	rarD	-	-	-	-	-	-	-	-	-	-	-	EamA
gnl|extdb|FAM1414-i1-1.1_001351	1122998.AUHZ01000004_gene1126	3.29e-147	415.0	COG2304@1|root,COG2304@2|Bacteria,2IFH7@201174|Actinobacteria,4DTS5@85009|Propionibacteriales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
gnl|extdb|FAM1414-i1-1.1_001352	1122998.AUHZ01000004_gene1127	4.12e-77	231.0	2EASN@1|root,334UM@2|Bacteria,2GSVP@201174|Actinobacteria,4DSAQ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001353	1122998.AUHZ01000004_gene1128	1.51e-126	359.0	COG0262@1|root,COG0262@2|Bacteria,2IHZ7@201174|Actinobacteria,4DUXF@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
gnl|extdb|FAM1414-i1-1.1_001354	1238186.AOCN01000010_gene1432	8.31e-61	195.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4FME5@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
gnl|extdb|FAM1414-i1-1.1_001355	1146883.BLASA_1816	9.57e-137	418.0	COG4694@1|root,COG4694@2|Bacteria,2II3K@201174|Actinobacteria	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13
gnl|extdb|FAM1414-i1-1.1_001356	754252.PFREUD_21240	3.65e-94	275.0	COG1974@1|root,COG1974@2|Bacteria,2GPJI@201174|Actinobacteria	201174|Actinobacteria	KT	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
gnl|extdb|FAM1414-i1-1.1_001357	754252.PFREUD_21250	0.0	870.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
gnl|extdb|FAM1414-i1-1.1_001358	754252.PFREUD_21260	4.91e-95	276.0	2EMV9@1|root,33FHI@2|Bacteria,2GZNR@201174|Actinobacteria	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001361	1121017.AUFG01000001_gene3124	4.54e-28	112.0	COG0610@1|root,COG0610@2|Bacteria,2HI69@201174|Actinobacteria,4FHJD@85021|Intrasporangiaceae	201174|Actinobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoR124_C,HSDR_N,ResIII
gnl|extdb|FAM1414-i1-1.1_001368	754252.PFREUD_16760	4.49e-167	466.0	COG2761@1|root,COG2761@2|Bacteria,2GNBC@201174|Actinobacteria,4DQ7I@85009|Propionibacteriales	201174|Actinobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
gnl|extdb|FAM1414-i1-1.1_001372	754252.PFREUD_16730	6.05e-93	272.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	yvgK	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
gnl|extdb|FAM1414-i1-1.1_001373	1203605.HMPREF1531_01557	1.49e-83	263.0	2BGT1@1|root,32ASH@2|Bacteria,2H7BX@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
gnl|extdb|FAM1414-i1-1.1_001365	754252.PFREUD_16790	7.87e-221	610.0	COG0583@1|root,COG0583@2|Bacteria,2GTX3@201174|Actinobacteria,4DQK8@85009|Propionibacteriales	201174|Actinobacteria	K	LysR substrate binding domain	-	-	-	ko:K09681	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
gnl|extdb|FAM1414-i1-1.1_001366	754252.PFREUD_16780	7.71e-263	724.0	COG0477@1|root,COG2814@2|Bacteria,2GMWE@201174|Actinobacteria,4DTEB@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	ynfM	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1,Sugar_tr
gnl|extdb|FAM1414-i1-1.1_001375	754252.PFREUD_22700	8.26e-105	303.0	2DSUA@1|root,33HFA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001376	754252.PFREUD_22690	2.79e-97	283.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
gnl|extdb|FAM1414-i1-1.1_001377	754252.PFREUD_22680	0.0	1489.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4DN1Q@85009|Propionibacteriales	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
gnl|extdb|FAM1414-i1-1.1_001379	1122998.AUHZ01000028_gene9	1.57e-65	199.0	2ATJW@1|root,31J3Z@2|Bacteria,2IKN0@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
gnl|extdb|FAM1414-i1-1.1_001380	754252.PFREUD_22650	1.97e-227	626.0	COG4974@1|root,COG4974@2|Bacteria,2IGA2@201174|Actinobacteria,4DT9K@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
gnl|extdb|FAM1414-i1-1.1_001381	1122998.AUHZ01000028_gene11	1.28e-76	236.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4DTJE@85009|Propionibacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
gnl|extdb|FAM1414-i1-1.1_001382	754252.PFREUD_22630	1.51e-121	347.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria	201174|Actinobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
gnl|extdb|FAM1414-i1-1.1_001383	1122998.AUHZ01000028_gene12	7e-123	351.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
gnl|extdb|FAM1414-i1-1.1_001384	77635.BISU_1961	3.36e-43	149.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria,4D2KU@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
gnl|extdb|FAM1414-i1-1.1_001385	1184609.KILIM_018_00570	7.77e-11	62.4	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4F7RM@85018|Dermatophilaceae	201174|Actinobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
gnl|extdb|FAM1414-i1-1.1_001387	754252.PFREUD_22580	8.63e-33	113.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	tnp3521a1	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
gnl|extdb|FAM1414-i1-1.1_001388	1287475.HMPREF1650_06440	1.92e-54	171.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria,22N9U@1653|Corynebacteriaceae	201174|Actinobacteria	L	transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
gnl|extdb|FAM1414-i1-1.1_001389	754252.PFREUD_22560	1.06e-281	769.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4DQAY@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_001391	1220583.GOACH_42_00020	4.4e-73	228.0	COG5502@1|root,COG5502@2|Bacteria,2I9TQ@201174|Actinobacteria,4GDEI@85026|Gordoniaceae	201174|Actinobacteria	S	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001386	1170318.PALO_02770	9.97e-62	195.0	2E9IE@1|root,333RF@2|Bacteria,2GTQZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001390	754252.PFREUD_22550	2.25e-84	251.0	2CAW2@1|root,32RS7@2|Bacteria,2IB15@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001392	1122997.AUDD01000042_gene1168	0.0	1069.0	COG2939@1|root,COG2939@2|Bacteria,2GK9N@201174|Actinobacteria,4DT28@85009|Propionibacteriales	201174|Actinobacteria	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
gnl|extdb|FAM1414-i1-1.1_001394	1122997.AUDD01000042_gene1170	0.0	936.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4DNQ3@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
gnl|extdb|FAM1414-i1-1.1_001395	1122997.AUDD01000042_gene1171	1.06e-193	538.0	COG1028@1|root,COG1028@2|Bacteria,2GJ9X@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
gnl|extdb|FAM1414-i1-1.1_001396	1122997.AUDD01000042_gene1172	2.22e-153	435.0	COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4DUP4@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_001397	1122997.AUDD01000042_gene1173	3.21e-213	589.0	COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4DUM9@85009|Propionibacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
gnl|extdb|FAM1414-i1-1.1_001398	1122997.AUDD01000042_gene1174	7.6e-149	420.0	COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type metal ion transport system permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
gnl|extdb|FAM1414-i1-1.1_001399	1122997.AUDD01000042_gene1175	1.18e-153	436.0	COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4DPJ9@85009|Propionibacteriales	201174|Actinobacteria	P	NLPA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
gnl|extdb|FAM1414-i1-1.1_001400	1429046.RR21198_5965	1.43e-147	435.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria,4FXGX@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
gnl|extdb|FAM1414-i1-1.1_001393	1122997.AUDD01000042_gene1169	0.0	1233.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	copB	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
gnl|extdb|FAM1414-i1-1.1_001401	1170318.PALO_00230	1.05e-45	155.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001402	754252.PFREUD_24530	7.06e-175	493.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4DTG9@85009|Propionibacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001403	1123251.ATWM01000005_gene1519	4.73e-17	83.2	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4FF8P@85021|Intrasporangiaceae	201174|Actinobacteria	L	zinc-finger of transposase IS204/IS1001/IS1096/IS1165	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001404	754252.PFREUD_01180	1.39e-231	636.0	29PMQ@1|root,30AJW@2|Bacteria,2I95H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001405	1170318.PALO_00230	6.48e-46	154.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001406	754252.PFREUD_24530	9.22e-53	176.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4DTG9@85009|Propionibacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001407	754252.PFREUD_24230	0.0	890.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001408	754252.PFREUD_00550	7.08e-210	583.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4DPM2@85009|Propionibacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
gnl|extdb|FAM1414-i1-1.1_001409	754252.PFREUD_00540	1.33e-255	712.0	COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,2GNY8@201174|Actinobacteria,4DN84@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind,dTDP_sugar_isom
gnl|extdb|FAM1414-i1-1.1_001410	1151122.AQYD01000006_gene2257	8.97e-208	611.0	COG4485@1|root,COG4485@2|Bacteria,2HT0R@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001633	1292373.H640_03296	1.01e-48	158.0	COG0847@1|root,COG0847@2|Bacteria,2IRF3@201174|Actinobacteria	201174|Actinobacteria	L	CRISPR-associated protein Cas2	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978
gnl|extdb|FAM1414-i1-1.1_001634	1292373.H640_03301	1.72e-152	436.0	COG1518@1|root,COG1518@2|Bacteria,2GKQ0@201174|Actinobacteria	201174|Actinobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
gnl|extdb|FAM1414-i1-1.1_001636	1051006.HMPREF1162_1254	7.09e-86	261.0	2DBXF@1|root,2ZBPB@2|Bacteria,2IHYA@201174|Actinobacteria	201174|Actinobacteria	S	CRISPR-associated protein	casD	-	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
gnl|extdb|FAM1414-i1-1.1_001637	1292373.H640_03316	2.51e-102	313.0	COG1857@1|root,COG1857@2|Bacteria,2GJ3A@201174|Actinobacteria	201174|Actinobacteria	L	CRISPR-associated protein	casC	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
gnl|extdb|FAM1414-i1-1.1_001638	1292373.H640_03321	2.08e-39	142.0	2DP12@1|root,33037@2|Bacteria,2IR0Y@201174|Actinobacteria	201174|Actinobacteria	S	CRISPR-associated protein, Cse2	casB	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse2
gnl|extdb|FAM1414-i1-1.1_001639	223184.AS25_13380	1.03e-20	89.7	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,1W8U7@1268|Micrococcaceae	201174|Actinobacteria	L	4.5 Transposon and IS	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001635	1170318.PALO_00015	4.65e-64	205.0	2DKU6@1|root,30BEK@2|Bacteria,2GNNP@201174|Actinobacteria	201174|Actinobacteria	S	CRISPR-associated protein	casE	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
gnl|extdb|FAM1414-i1-1.1_001640	754252.PFREUD_01070	4.59e-12	66.6	COG0515@1|root,COG0515@2|Bacteria,2GM6E@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NPCBM,Pkinase
gnl|extdb|FAM1414-i1-1.1_001643	754252.PFREUD_00970	2.01e-208	576.0	29J5I@1|root,3062Y@2|Bacteria,2I9N8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001644	754252.PFREUD_00960	2.2e-155	438.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,4DTAB@85009|Propionibacteriales	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
gnl|extdb|FAM1414-i1-1.1_001645	754252.PFREUD_01040	2.96e-27	112.0	COG1070@1|root,COG1070@2|Bacteria,2IAKI@201174|Actinobacteria,4DTR5@85009|Propionibacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
gnl|extdb|FAM1414-i1-1.1_001646	754252.PFREUD_00930	2.14e-257	706.0	2DGZY@1|root,2ZXX0@2|Bacteria,2HDJM@201174|Actinobacteria	201174|Actinobacteria	S	function, without similarity to other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001647	1449058.JQKT01000013_gene324	3.87e-16	73.6	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4FPPT@85023|Microbacteriaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
gnl|extdb|FAM1414-i1-1.1_001648	754252.PFREUD_00910	3.63e-92	273.0	2B9CE@1|root,322Q4@2|Bacteria,2IKT2@201174|Actinobacteria,4DRJ3@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
gnl|extdb|FAM1414-i1-1.1_001649	754252.PFREUD_00900	5.18e-251	690.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4DP5Z@85009|Propionibacteriales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
gnl|extdb|FAM1414-i1-1.1_001651	754252.PFREUD_24270	1.41e-35	130.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001642	754252.PFREUD_00980	0.0	1521.0	COG3256@1|root,COG3256@2|Bacteria,2I6ZN@201174|Actinobacteria	201174|Actinobacteria	P	nitric oxide reductase	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
gnl|extdb|FAM1414-i1-1.1_001650	1232429.CBLL010000159_gene654	8.93e-18	82.4	COG4227@1|root,COG4227@2|Bacteria,2I2PD@201174|Actinobacteria,1WCFW@1268|Micrococcaceae	201174|Actinobacteria	L	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738,Peptidase_M78
gnl|extdb|FAM1414-i1-1.1_001652	1089455.MOPEL_097_00020	4.53e-77	243.0	COG5502@1|root,COG5502@2|Bacteria,2I9TQ@201174|Actinobacteria	201174|Actinobacteria	S	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001654	754252.PFREUD_22750	6.21e-128	364.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_7,Resolvase
gnl|extdb|FAM1414-i1-1.1_001655	754252.PFREUD_22760	7.4e-180	501.0	COG2253@1|root,COG2253@2|Bacteria,2I3Y9@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
gnl|extdb|FAM1414-i1-1.1_001656	754252.PFREUD_22770	4.11e-77	229.0	2ES0Y@1|root,2ZIQJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001657	754252.PFREUD_22780	1.04e-102	298.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4DQU3@85009|Propionibacteriales	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20)	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
gnl|extdb|FAM1414-i1-1.1_001658	754252.PFREUD_22790	3.03e-104	301.0	COG0071@1|root,COG0071@2|Bacteria,2IRG0@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
gnl|extdb|FAM1414-i1-1.1_001659	754252.PFREUD_22800	0.0	1199.0	COG3158@1|root,COG3158@2|Bacteria,2GMPQ@201174|Actinobacteria,4DU3B@85009|Propionibacteriales	201174|Actinobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
gnl|extdb|FAM1414-i1-1.1_001660	754252.PFREUD_21300	4.17e-196	555.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_30,Toprim_2,Toprim_3,Toprim_N,TrwC,zf-CHC2
gnl|extdb|FAM1414-i1-1.1_001661	1171373.PACID_03870	0.0	952.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4DQAY@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_001662	1122998.AUHZ01000019_gene1687	0.0	884.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4DNX4@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	merA	-	1.16.1.1	ko:K00520,ko:K21739	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
gnl|extdb|FAM1414-i1-1.1_001667	754252.PFREUD_24460	9.2e-195	540.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DUKR@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve,rve_3
gnl|extdb|FAM1414-i1-1.1_001668	754252.PFREUD_24470	1.58e-66	202.0	COG2963@1|root,COG2963@2|Bacteria,2IMAC@201174|Actinobacteria	201174|Actinobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
gnl|extdb|FAM1414-i1-1.1_001670	321955.AAGP01000051_gene3591	9.14e-41	135.0	COG2608@1|root,COG2608@2|Bacteria,2GQMZ@201174|Actinobacteria,4FAKK@85019|Brevibacteriaceae	201174|Actinobacteria	P	Heavy-metal-associated domain	copZ	-	-	-	-	-	-	-	-	-	-	-	HMA
gnl|extdb|FAM1414-i1-1.1_001671	861360.AARI_06640	8.13e-127	364.0	COG0664@1|root,COG0664@2|Bacteria,2IKTT@201174|Actinobacteria,1W9PR@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
gnl|extdb|FAM1414-i1-1.1_001669	1449058.JQKT01000007_gene1345	0.0	947.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4FMAV@85023|Microbacteriaceae	201174|Actinobacteria	P	E1-E2 ATPase	copA	-	3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
gnl|extdb|FAM1414-i1-1.1_001672	754252.PFREUD_23090	1.55e-170	476.0	COG3967@1|root,COG3967@2|Bacteria,2GP7V@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
gnl|extdb|FAM1414-i1-1.1_001673	754252.PFREUD_23080	3.71e-208	577.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
gnl|extdb|FAM1414-i1-1.1_001674	754252.PFREUD_23070	5.05e-184	514.0	COG1737@1|root,COG1737@2|Bacteria,2IIAF@201174|Actinobacteria	201174|Actinobacteria	K	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
gnl|extdb|FAM1414-i1-1.1_001675	754252.PFREUD_23060	5.24e-166	468.0	COG0697@1|root,COG0697@2|Bacteria,2GMPU@201174|Actinobacteria,4DS3N@85009|Propionibacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
gnl|extdb|FAM1414-i1-1.1_001677	754252.PFREUD_24230	3.61e-41	145.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001678	1122997.AUDD01000010_gene800	1.1e-25	96.7	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DUKR@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve,rve_3
gnl|extdb|FAM1414-i1-1.1_001681	754252.PFREUD_20750	3.26e-101	294.0	2DPPE@1|root,332VJ@2|Bacteria,2IN30@201174|Actinobacteria,4DSE1@85009|Propionibacteriales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
gnl|extdb|FAM1414-i1-1.1_001682	754252.PFREUD_20740	8.58e-290	791.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4DNGP@85009|Propionibacteriales	201174|Actinobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
gnl|extdb|FAM1414-i1-1.1_001683	1122998.AUHZ01000010_gene1562	4.41e-26	97.8	COG2801@1|root,COG2801@2|Bacteria,2GTHN@201174|Actinobacteria,4DWUJ@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
gnl|extdb|FAM1414-i1-1.1_001686	754252.PFREUD_24800	1.51e-139	395.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	yagA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_29,HTH_32,LZ_Tnp_IS481,rve,rve_3
gnl|extdb|FAM1414-i1-1.1_001687	1285583.CCASEI_09485	9.42e-26	95.1	2AUJT@1|root,31K8D@2|Bacteria,2HEBX@201174|Actinobacteria,22PI3@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
gnl|extdb|FAM1414-i1-1.1_001688	1121353.H924_02745	0.0	1149.0	COG0277@1|root,COG0277@2|Bacteria,2IB1Z@201174|Actinobacteria,22MFP@1653|Corynebacteriaceae	201174|Actinobacteria	C	Catalyzes the oxidation of D-lactate to pyruvate	dld	-	1.1.5.12	ko:K03777	ko00620,ko01120,map00620,map01120	-	R00704,R11591	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD_binding_4,Lact-deh-memb
gnl|extdb|FAM1414-i1-1.1_001685	1077972.ARGLB_047_00540	2.96e-12	67.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2ITEV@201174|Actinobacteria,1WBN4@1268|Micrococcaceae	201174|Actinobacteria	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
gnl|extdb|FAM1414-i1-1.1_001691	861360.AARI_29420	1.66e-77	230.0	COG1695@1|root,COG1695@2|Bacteria,2GRHC@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
gnl|extdb|FAM1414-i1-1.1_001693	223184.AS25_13380	1.03e-20	89.7	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,1W8U7@1268|Micrococcaceae	201174|Actinobacteria	L	4.5 Transposon and IS	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001689	749927.AMED_8302	2.72e-35	139.0	COG2159@1|root,COG2159@2|Bacteria,2IC9Z@201174|Actinobacteria,4EEUC@85010|Pseudonocardiales	201174|Actinobacteria	S	AIPR protein	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	AIPR
gnl|extdb|FAM1414-i1-1.1_001931	1121372.AULK01000004_gene1399	0.0	876.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4FM4P@85023|Microbacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001933	754252.PFREUD_02920	6.74e-80	255.0	COG3409@1|root,COG3409@2|Bacteria,2GMEN@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,PG_binding_1
gnl|extdb|FAM1414-i1-1.1_001934	1246995.AFR_29520	4.6e-81	265.0	COG2159@1|root,COG2159@2|Bacteria,2IC9Z@201174|Actinobacteria	201174|Actinobacteria	S	AIPR protein	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	AIPR
gnl|extdb|FAM1414-i1-1.1_001935	754252.PFREUD_24830	2.44e-285	780.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4DQAY@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_001936	710685.MycrhN_2941	0.0	887.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,237B6@1762|Mycobacteriaceae	201174|Actinobacteria	L	transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
gnl|extdb|FAM1414-i1-1.1_001937	1229781.C272_16245	4.08e-247	678.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4FAZ2@85019|Brevibacteriaceae	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
gnl|extdb|FAM1414-i1-1.1_001939	1171373.PACID_04050	6.17e-90	274.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
## 2250 queries scanned
## Total time (seconds): 5.35212254524231
## Rate: 420.39 q/s