# emapper version: emapper-1.0.3-35-g63c274b emapper DB: 2.0 # command: ./emapper.py --cpu 6 -i /data/shared/emapper_jobs/user_data/MM_uvkqps_l/query_seqs.fa --output query_seqs.fa --output_dir /data/shared/emapper_jobs/user_data/MM_uvkqps_l -m diamond -d none --tax_scope auto --go_evidence non-electronic --target_orthologs all --seed_ortholog_evalue 0.001 --seed_ortholog_score 60 --query-cover 20 --subject-cover 0 --override --temp_dir /data/shared/emapper_jobs/user_data/MM_uvkqps_l # time: Fri May 29 15:43:39 2020 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction gnl|extdb|FAM1079-i1-1.1_000001 1114972.AUAW01000027_gene720 1.3e-08 64.3 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_000002 797515.HMPREF9103_00509 2.9e-216 757.7 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family gnl|extdb|FAM1079-i1-1.1_000003 797515.HMPREF9103_00508 9.4e-217 759.2 Lactobacillaceae hpk31 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPB6@1239,3F479@33958,4HARU@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM1079-i1-1.1_000004 797515.HMPREF9103_00507 5.4e-124 450.3 Lactobacillaceae Bacteria 1TP9M@1239,3F3Y0@33958,4HB3T@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator gnl|extdb|FAM1079-i1-1.1_000005 797515.HMPREF9103_00506 5.6e-94 350.1 Lactobacillaceae ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1V3V3@1239,3F70T@33958,4HHNY@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_000006 797515.HMPREF9103_00505 1.9e-68 265.0 Lactobacillaceae def 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V73T@1239,3F6ZA@33958,4HISW@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins gnl|extdb|FAM1079-i1-1.1_000007 797515.HMPREF9103_00504 1.2e-255 888.6 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP gnl|extdb|FAM1079-i1-1.1_000008 525318.HMPREF0497_1103 5.7e-114 417.2 Lactobacillaceae 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1UZ4E@1239,3FB80@33958,4HE6E@91061,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F NUDIX domain gnl|extdb|FAM1079-i1-1.1_000009 797515.HMPREF9103_00500 5.5e-107 393.7 Lactobacillaceae zmp1 Bacteria 1VW9X@1239,3F60X@33958,4HWF8@91061,COG5549@1,COG5549@2 NA|NA|NA O PFAM peptidase M10A and M12B, matrixin and adamalysin gnl|extdb|FAM1079-i1-1.1_000010 797515.HMPREF9103_00499 1.7e-124 452.2 Lactobacillaceae qmcA GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TPXU@1239,3F4HV@33958,4HGRC@91061,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues gnl|extdb|FAM1079-i1-1.1_000011 797515.HMPREF9103_00498 3.1e-53 214.2 Lactobacillaceae Bacteria 1W0S9@1239,3F76E@33958,4HZDX@91061,COG4226@1,COG4226@2 NA|NA|NA S protein encoded in hypervariable junctions of pilus gene clusters gnl|extdb|FAM1079-i1-1.1_000012 797515.HMPREF9103_00497 7e-209 733.0 Lactobacillaceae guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1TNZ1@1239,3F3XN@33958,4H9V3@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides gnl|extdb|FAM1079-i1-1.1_000013 797515.HMPREF9103_00495 2.9e-131 474.6 Lactobacillaceae XK27_01040 Bacteria 1VF5N@1239,3F4JS@33958,4HH7B@91061,COG4858@1,COG4858@2 NA|NA|NA S Protein of unknown function (DUF1129) gnl|extdb|FAM1079-i1-1.1_000014 797515.HMPREF9103_00494 1e-201 709.1 Lactobacillaceae ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1TPRK@1239,3F3TK@33958,4H9SQ@91061,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner gnl|extdb|FAM1079-i1-1.1_000015 797515.HMPREF9103_00493 2.3e-32 144.1 Lactobacillaceae yyzM Bacteria 1VEQ7@1239,3F823@33958,4HNHU@91061,COG4481@1,COG4481@2 NA|NA|NA S Bacterial protein of unknown function (DUF951) gnl|extdb|FAM1079-i1-1.1_000016 797515.HMPREF9103_00492 1.7e-154 552.0 Lactobacillaceae spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TQ2B@1239,3F47R@33958,4H9TB@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family gnl|extdb|FAM1079-i1-1.1_000017 797515.HMPREF9103_00491 7.4e-138 496.5 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3F4AE@33958,4HAYM@91061,COG1192@1,COG1192@2 NA|NA|NA D Sporulation initiation inhibitor gnl|extdb|FAM1079-i1-1.1_000018 797515.HMPREF9103_00490 1.2e-126 459.1 Lactobacillaceae rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1TPBT@1239,3F3ZX@33958,4HAAZ@91061,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA gnl|extdb|FAM1079-i1-1.1_000019 797515.HMPREF9103_00489 4.3e-247 860.1 Lactobacillaceae pepT2 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3FB44@33958,4HA04@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides gnl|extdb|FAM1079-i1-1.1_000020 797515.HMPREF9103_00487 3.9e-170 604.0 Lactobacillaceae rihC 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSSS@1239,3F4T0@33958,4HB17@91061,COG1957@1,COG1957@2 NA|NA|NA F Nucleoside gnl|extdb|FAM1079-i1-1.1_000021 797515.HMPREF9103_00486 2.1e-225 788.1 Lactobacillaceae pbuO_1 ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F4I2@33958,4HBDC@91061,COG2252@1,COG2252@2 NA|NA|NA S Permease family gnl|extdb|FAM1079-i1-1.1_000022 797515.HMPREF9103_00485 1.6e-230 805.1 Lactobacillaceae nupG GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015212,GO:0015213,GO:0015214,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015506,GO:0015672,GO:0015858,GO:0015861,GO:0015862,GO:0015864,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072531,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1901505,GO:1901642,GO:1902600 ko:K03317,ko:K16323 ko00000,ko02000 2.A.41,2.A.41.1 Bacteria 1TRSK@1239,3F4GI@33958,4HA8N@91061,COG1972@1,COG1972@2 NA|NA|NA F Nucleoside gnl|extdb|FAM1079-i1-1.1_000023 797515.HMPREF9103_00484 1e-153 549.3 Lactobacillaceae 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 R01057,R02749 RC00408 ko00000,ko00001,ko01000 Bacteria 1TP70@1239,3F5Y0@33958,4H9RU@91061,COG1015@1,COG1015@2 NA|NA|NA G Metalloenzyme superfamily gnl|extdb|FAM1079-i1-1.1_000024 797515.HMPREF9103_02168 1.3e-79 303.5 Lactobacillaceae Bacteria 1U5MD@1239,29NUM@1,309SQ@2,3F66S@33958,4IFC6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000025 525318.HMPREF0497_1083 2.1e-163 582.0 Lactobacillaceae Bacteria 1U5AU@1239,2C146@1,346DU@2,3F5EF@33958,4IF29@91061 NA|NA|NA S GDSL-like Lipase/Acylhydrolase gnl|extdb|FAM1079-i1-1.1_000026 797515.HMPREF9103_02164 7e-127 460.3 Lactobacillaceae Bacteria 1U5D5@1239,29XME@1,309N6@2,3F5KZ@33958,4IF4G@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000028 797515.HMPREF9103_00039 1.3e-206 726.1 Lactobacillaceae Bacteria 1U5KD@1239,29XME@1,309S1@2,3F64M@33958,4IFB6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000029 797515.HMPREF9103_00038 2.1e-35 154.5 Lactobacillaceae Bacteria 1U795@1239,29PZN@1,30AY3@2,3F955@33958,4IH41@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000030 797515.HMPREF9103_00036 3.8e-63 247.3 Lactobacillaceae Bacteria 1U64Y@1239,29P56@1,30A3D@2,3F726@33958,4IFUP@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000031 797515.HMPREF9103_00035 6e-82 310.1 Lactobacillaceae gepA Bacteria 1UK2I@1239,3F4EH@33958,4ITGB@91061,COG3600@1,COG3600@2 NA|NA|NA K Protein of unknown function (DUF4065) gnl|extdb|FAM1079-i1-1.1_000032 797515.HMPREF9103_00034 2.8e-114 417.9 Lactobacillaceae cah 4.2.1.1 ko:K01674 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1V16J@1239,3F7DZ@33958,4HA62@91061,COG3338@1,COG3338@2 NA|NA|NA P Eukaryotic-type carbonic anhydrase gnl|extdb|FAM1079-i1-1.1_000033 797515.HMPREF9103_00033 6.5e-179 633.3 Lactobacillaceae kdgR ko:K02525 ko00000,ko03000 Bacteria 1VSEE@1239,3FC5F@33958,4HTEF@91061,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor gnl|extdb|FAM1079-i1-1.1_000034 797515.HMPREF9103_00032 5.8e-89 333.6 Lactobacillaceae hxlB 4.1.2.14,4.1.2.43,4.1.3.42,5.3.1.27 ko:K01625,ko:K08094,ko:K13831 ko00030,ko00630,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00630,map00680,map01100,map01120,map01200,map01230 M00008,M00061,M00308,M00345,M00580,M00631 R00470,R05338,R05339,R05605,R09780 RC00307,RC00308,RC00377,RC00421,RC00422,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3UJ@1239,3F7I2@33958,4HH5G@91061,COG0794@1,COG0794@2 NA|NA|NA M sugar phosphate isomerase involved in capsule formation gnl|extdb|FAM1079-i1-1.1_000035 797515.HMPREF9103_00031 2.9e-108 397.9 Lactobacillaceae hxlA 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4B6@1239,3F6EU@33958,4HHY5@91061,COG0269@1,COG0269@2 NA|NA|NA G Orotidine 5'-phosphate decarboxylase HUMPS family gnl|extdb|FAM1079-i1-1.1_000036 797515.HMPREF9103_00030 2.3e-165 588.2 Lactobacillaceae kdgK 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRRY@1239,3F4FT@33958,4HBH6@91061,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM1079-i1-1.1_000037 797515.HMPREF9103_00029 2e-228 798.1 Lactobacillaceae gntT Bacteria 1UIHX@1239,3F4AP@33958,4ISSR@91061,COG2610@1,COG2610@2 NA|NA|NA EG Citrate transporter gnl|extdb|FAM1079-i1-1.1_000038 797515.HMPREF9103_00028 1.1e-138 499.2 Lactobacillaceae kguE 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V82S@1239,3FBQ6@33958,4IRUU@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel gnl|extdb|FAM1079-i1-1.1_000039 797515.HMPREF9103_00026 2.4e-248 864.4 Lactobacillaceae Bacteria 1TREV@1239,3F4NG@33958,4HAN1@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000040 797515.HMPREF9103_00025 1.2e-148 532.7 Lactobacillaceae MA20_41405 Bacteria 1UGEU@1239,3F5TN@33958,4IF6K@91061,COG2340@1,COG2340@2 NA|NA|NA S Cysteine-rich secretory protein family gnl|extdb|FAM1079-i1-1.1_000041 1114972.AUAW01000012_gene1146 1e-64 255.4 Lactobacillaceae Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2 NA|NA|NA M Bacterial Ig-like domain (group 3) gnl|extdb|FAM1079-i1-1.1_000042 797515.HMPREF9103_00024 4.5e-156 557.4 Bacteria Bacteria COG5549@1,COG5549@2 NA|NA|NA O protein import gnl|extdb|FAM1079-i1-1.1_000043 797515.HMPREF9103_00023 4.3e-302 1043.1 Lactobacillaceae 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1VSNK@1239,3F4VP@33958,4HU8G@91061,COG0438@1,COG0438@2 NA|NA|NA M Poly(Glycerol-phosphate) alpha-glucosyltransferase gnl|extdb|FAM1079-i1-1.1_000044 797515.HMPREF9103_00022 1.3e-306 1058.1 Lactobacillaceae tagE3 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1TR6K@1239,3FBGJ@33958,4IQBA@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein gnl|extdb|FAM1079-i1-1.1_000045 797515.HMPREF9103_00021 2.6e-49 201.1 Lactobacillaceae Bacteria 1U82K@1239,29QGS@1,30BG6@2,3FAGA@33958,4IHZZ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000046 797515.HMPREF9103_00020 8.8e-78 296.2 Lactobacillaceae Bacteria 1UYXM@1239,3F667@33958,4HD96@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase gnl|extdb|FAM1079-i1-1.1_000047 797515.HMPREF9103_00019 9.5e-175 619.4 Lactobacillaceae manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,3F40I@33958,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase gnl|extdb|FAM1079-i1-1.1_000048 1423743.JCM14108_1763 2.6e-234 818.1 Firmicutes Bacteria 1UKBZ@1239,COG3664@1,COG3664@2 NA|NA|NA G leucine binding gnl|extdb|FAM1079-i1-1.1_000049 797515.HMPREF9103_00018 3.4e-244 850.5 Lactobacillaceae ydjK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08369 ko00000,ko02000 2.A.1 Bacteria 1UJGJ@1239,3FBY5@33958,4IT9D@91061,COG2271@1,COG2271@2 NA|NA|NA G Sugar (and other) transporter gnl|extdb|FAM1079-i1-1.1_000050 797515.HMPREF9103_00017 2e-111 408.3 Lactobacillaceae leuD 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1V1I6@1239,3F47W@33958,4HFTY@91061,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate gnl|extdb|FAM1079-i1-1.1_000051 797515.HMPREF9103_00016 9.1e-272 942.2 Lactobacillaceae leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700 Bacteria 1TPE5@1239,3F4KF@33958,4HAWA@91061,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate gnl|extdb|FAM1079-i1-1.1_000052 797515.HMPREF9103_00015 9.5e-200 702.6 Lactobacillaceae leuB GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TPEM@1239,3F4AY@33958,4HATP@91061,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate gnl|extdb|FAM1079-i1-1.1_000053 797515.HMPREF9103_00014 5.1e-215 753.4 Lactobacillaceae leuA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS10690,iYO844.BSU28280 Bacteria 1TP4Y@1239,3F581@33958,4HA6E@91061,COG0119@1,COG0119@2 NA|NA|NA E Belongs to the alpha-IPM synthase homocitrate synthase family gnl|extdb|FAM1079-i1-1.1_000054 797515.HMPREF9103_00013 5.7e-118 430.6 Lactobacillaceae Bacteria 1V8CG@1239,3F6RS@33958,4HGZV@91061,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase gnl|extdb|FAM1079-i1-1.1_000055 797515.HMPREF9103_00009 0.0 1663.7 Lactobacillaceae xpkA 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F5FX@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G XFP C-terminal domain gnl|extdb|FAM1079-i1-1.1_000056 797515.HMPREF9103_00008 7e-127 459.9 Lactobacillaceae Bacteria 1UI5G@1239,3F652@33958,4ISEF@91061,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family gnl|extdb|FAM1079-i1-1.1_000057 1423743.JCM14108_2934 2.1e-47 194.9 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1UPNV@1239,3F6UK@33958,4IV86@91061,COG2337@1,COG2337@2 NA|NA|NA T Toxin-antitoxin system, toxin component, MazF family gnl|extdb|FAM1079-i1-1.1_000058 1400520.LFAB_14565 4.8e-15 87.0 Lactobacillaceae Bacteria 1U740@1239,29PVW@1,30AU6@2,3F8XY@33958,4IGYG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000059 797515.HMPREF9103_00006 5.9e-108 396.7 Lactobacillaceae ydeN ko:K07002 ko00000 Bacteria 1VB10@1239,3F6EJ@33958,4HMAD@91061,COG3545@1,COG3545@2 NA|NA|NA S Serine hydrolase gnl|extdb|FAM1079-i1-1.1_000060 1423734.JCM14202_3664 5e-43 180.6 Lactobacillaceae Bacteria 1VG8M@1239,3F6QY@33958,4HYHM@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000061 1423734.JCM14202_3663 2.4e-184 651.7 Lactobacillaceae Bacteria 1UHNW@1239,3FCCP@33958,4IS4S@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000063 797515.HMPREF9103_00004 0.0 1206.4 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZHI@1239,3F4A4@33958,4I3MZ@91061,COG1053@1,COG1053@2,COG3976@1,COG3976@2 NA|NA|NA C FMN_bind gnl|extdb|FAM1079-i1-1.1_000064 797515.HMPREF9103_00003 1.7e-160 572.0 Lactobacillaceae Bacteria 1U35Y@1239,3FBI9@33958,4HCXK@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain gnl|extdb|FAM1079-i1-1.1_000065 797515.HMPREF9103_00002 1.6e-141 508.8 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VA8S@1239,3F5HF@33958,4HPR4@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM1079-i1-1.1_000066 797515.HMPREF9103_02394 0.0 1209.9 Lactobacillaceae phnX GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.1.3.18,3.11.1.1 ko:K01091,ko:K01740,ko:K03430,ko:K05306 ko00270,ko00440,ko00630,ko01100,ko01110,ko01120,ko01130,map00270,map00440,map00630,map01100,map01110,map01120,map01130 R00747,R01287,R01334,R04152,R04859 RC00008,RC00017,RC00020,RC00062,RC00368,RC02821,RC02848 ko00000,ko00001,ko01000,ko01007 Bacteria 1TPS0@1239,3F43T@33958,4HBFN@91061,COG0075@1,COG0075@2,COG0637@1,COG0637@2 NA|NA|NA E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily gnl|extdb|FAM1079-i1-1.1_000067 797515.HMPREF9103_02393 1.5e-150 538.9 Lactobacillaceae phnE1 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TQ73@1239,3FB6V@33958,4HD3S@91061,COG3639@1,COG3639@2 NA|NA|NA U ABC transporter permease gnl|extdb|FAM1079-i1-1.1_000068 797515.HMPREF9103_02392 5.5e-136 490.3 Lactobacillaceae phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TR1S@1239,3FB6W@33958,4HDQQ@91061,COG3639@1,COG3639@2 NA|NA|NA U Phosphonate ABC transporter permease gnl|extdb|FAM1079-i1-1.1_000069 797515.HMPREF9103_02391 5.4e-133 480.3 Lactobacillaceae phnC 3.6.3.28 ko:K02041 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TQG6@1239,3F3SJ@33958,4HC3N@91061,COG3638@1,COG3638@2 NA|NA|NA P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_000070 797515.HMPREF9103_02390 6.9e-184 649.8 Lactobacillaceae phnD ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1TR0H@1239,3F3KK@33958,4HBJQ@91061,COG3221@1,COG3221@2 NA|NA|NA P Phosphonate ABC transporter gnl|extdb|FAM1079-i1-1.1_000071 797515.HMPREF9103_02389 3e-159 567.8 Lactobacillaceae pdxS GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 ko:K06215 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 Bacteria 1TPSZ@1239,3F49H@33958,4H9RA@91061,COG0214@1,COG0214@2 NA|NA|NA H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively gnl|extdb|FAM1079-i1-1.1_000072 797515.HMPREF9103_02388 7e-98 363.2 Lactobacillaceae pdxT GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 Bacteria 1V3I6@1239,3F6QE@33958,4HFSZ@91061,COG0311@1,COG0311@2 NA|NA|NA H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS gnl|extdb|FAM1079-i1-1.1_000073 797515.HMPREF9103_02387 2e-52 211.5 Lactobacillaceae Bacteria 1W3JF@1239,298U1@1,2ZVY8@2,3F7JE@33958,4I1SS@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000074 797515.HMPREF9103_02386 1e-173 615.9 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily gnl|extdb|FAM1079-i1-1.1_000076 1203076.CAKF01000035_gene1009 1.1e-28 132.9 Lactobacillaceae doc ko:K07341 ko00000,ko02048 Bacteria 1VCC8@1239,3F7JS@33958,4HKXW@91061,COG3654@1,COG3654@2 NA|NA|NA S Fic/DOC family gnl|extdb|FAM1079-i1-1.1_000077 797515.HMPREF9103_02379 5.4e-144 516.9 Lactobacillaceae phnX 3.1.3.23,3.11.1.1 ko:K05306,ko:K07025,ko:K19270 ko00440,ko01100,ko01120,map00440,map01100,map01120 R00747 RC00368 ko00000,ko00001,ko01000 Bacteria 1TP1A@1239,3F5WZ@33958,4HC8X@91061,COG0637@1,COG0637@2 NA|NA|NA E Belongs to the HAD-like hydrolase superfamily. PhnX family gnl|extdb|FAM1079-i1-1.1_000079 797515.HMPREF9103_02377 9.1e-68 262.7 Lactobacillaceae Bacteria 1U6BT@1239,2BWXC@1,30A8G@2,3F7JA@33958,4IG3E@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000080 797515.HMPREF9103_02376 5.6e-206 723.4 Lactobacillaceae glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 1TPSI@1239,3F3V2@33958,4HA91@91061,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family gnl|extdb|FAM1079-i1-1.1_000082 797515.HMPREF9103_02374 8e-255 885.9 Lactobacillaceae potE5 ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F5DV@33958,4HATU@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM1079-i1-1.1_000083 797515.HMPREF9103_02372 6.9e-200 703.0 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase gnl|extdb|FAM1079-i1-1.1_000084 797515.HMPREF9103_02371 3.7e-128 464.2 Lactobacillaceae 2.1.1.157 ko:K18897 ko00260,map00260 R10061 RC00003,RC03040 ko00000,ko00001,ko01000 Bacteria 1UZU3@1239,3F7AM@33958,4HHH3@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain gnl|extdb|FAM1079-i1-1.1_000085 797515.HMPREF9103_02370 5.8e-230 803.1 Lactobacillaceae queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 1TP6Q@1239,3F5I3@33958,4HAEW@91061,COG1600@1,COG1600@2 NA|NA|NA C Domain of unknown function (DUF1730) gnl|extdb|FAM1079-i1-1.1_000086 797515.HMPREF9103_02369 1.6e-255 888.3 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM1079-i1-1.1_000087 797515.HMPREF9103_02368 0.0 1504.2 Lactobacillaceae uvrA2 Bacteria 1TR1H@1239,3F50Y@33958,4H9RE@91061,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter gnl|extdb|FAM1079-i1-1.1_000088 797515.HMPREF9103_02367 2.9e-66 258.8 Lactobacillaceae Bacteria 1U5ZF@1239,2DE6V@1,2ZKR8@2,3F6RD@33958,4IFNG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000089 1423780.LOT_2122 1e-143 517.7 Lactobacillaceae Bacteria 1TQBI@1239,3F4FM@33958,4HBAT@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein gnl|extdb|FAM1079-i1-1.1_000090 797515.HMPREF9103_02364 3.3e-234 817.4 Lactobacillaceae gshR 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase gnl|extdb|FAM1079-i1-1.1_000092 797515.HMPREF9103_02360 9.9e-64 249.2 Lactobacillaceae GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1VGE7@1239,3F6YB@33958,4HNE7@91061,COG3576@1,COG3576@2 NA|NA|NA S pyridoxamine 5-phosphate gnl|extdb|FAM1079-i1-1.1_000093 797515.HMPREF9103_02359 2.2e-252 877.9 Lactobacillaceae nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 1TQ3B@1239,3FB8Z@33958,4HCYW@91061,COG1757@1,COG1757@2 NA|NA|NA C Na H antiporter NhaC gnl|extdb|FAM1079-i1-1.1_000094 1071400.LBUCD034_1644 2.9e-67 261.5 Lactobacillaceae Bacteria 1VEM5@1239,3F66Z@33958,4HQRV@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator (TetR family) gnl|extdb|FAM1079-i1-1.1_000095 511437.Lbuc_1585 0.0 1192.6 Lactobacillaceae ko:K07003 ko00000 Bacteria 1VSWA@1239,3F4S6@33958,4HHPY@91061,COG1033@1,COG1033@2 NA|NA|NA S Protein export membrane protein gnl|extdb|FAM1079-i1-1.1_000096 797515.HMPREF9103_02358 2.6e-158 564.7 Lactobacillaceae Bacteria 1U728@1239,29PC0@1,30ASU@2,3F8VU@33958,4IGWP@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000097 797515.HMPREF9103_02357 4.6e-160 570.5 Lactobacillaceae Bacteria 1U728@1239,29PC0@1,30ASU@2,3F8VU@33958,4IGWP@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000098 797515.HMPREF9103_02356 2.4e-161 574.7 Lactobacillaceae Bacteria 1UZZS@1239,3F9HB@33958,4HA7Y@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain gnl|extdb|FAM1079-i1-1.1_000100 797515.HMPREF9103_02354 2.3e-178 631.7 Lactobacillaceae ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25 Bacteria 1UKTP@1239,3FBW0@33958,4ITJV@91061,COG2223@1,COG2223@2 NA|NA|NA P Major Facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000101 797515.HMPREF9103_02352 1.3e-187 662.1 Lactobacillaceae Bacteria 1UKTN@1239,3F5JQ@33958,4ITJU@91061,COG4977@1,COG4977@2 NA|NA|NA K AraC family transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000102 797515.HMPREF9103_02351 9.1e-259 899.0 Lactobacillaceae ko:K03292 ko00000 2.A.2 Bacteria 1TRA5@1239,3F3Z2@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G symporter gnl|extdb|FAM1079-i1-1.1_000103 797515.HMPREF9103_02350 0.0 1354.7 Lactobacillaceae 3.2.1.185 ko:K09955,ko:K18205 ko00000,ko01000 GH127 Bacteria 1TNYA@1239,3F57Z@33958,4HDGR@91061,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 gnl|extdb|FAM1079-i1-1.1_000105 1499689.CCNN01000007_gene2489 9.1e-56 223.0 Clostridiaceae yjaB 2.3.1.181 ko:K03801,ko:K03827 ko00785,ko01100,map00785,map01100 R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 1VAAI@1239,24ID9@186801,36J2R@31979,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_000106 797515.HMPREF9103_02321 0.0 1127.5 Lactobacillaceae spxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM1079-i1-1.1_000107 1302286.BAOT01000083_gene2225 3.1e-82 312.4 Lactobacillaceae Bacteria 1TP4A@1239,3F40X@33958,4HDAB@91061,COG3547@1,COG3547@2 NA|NA|NA L COG3547 Transposase and inactivated derivatives gnl|extdb|FAM1079-i1-1.1_000109 1136177.KCA1_2911 5.2e-13 80.1 Lactobacillaceae Bacteria 1VZ7R@1239,2DXGR@1,344Y7@2,3F842@33958,4HYQW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000110 1423743.JCM14108_1763 2.3e-203 715.7 Firmicutes Bacteria 1UKBZ@1239,COG3664@1,COG3664@2 NA|NA|NA G leucine binding gnl|extdb|FAM1079-i1-1.1_000111 797515.HMPREF9103_00571 0.0 1339.3 Lactobacillaceae 3.2.1.185 ko:K09955,ko:K18205 ko00000,ko01000 GH127 Bacteria 1TNYA@1239,3F57Z@33958,4HDGR@91061,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 gnl|extdb|FAM1079-i1-1.1_000112 1071400.LBUCD034_0242 8.9e-238 829.3 Lactobacillaceae melB ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 1TRA5@1239,3F3Z2@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G symporter gnl|extdb|FAM1079-i1-1.1_000113 1071400.LBUCD034_0241 9.4e-151 539.7 Lactobacillaceae Bacteria 1UKTN@1239,3F5JQ@33958,4ITJU@91061,COG4977@1,COG4977@2 NA|NA|NA K AraC family transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000114 797515.HMPREF9103_00568 4.9e-30 136.3 Lactobacillaceae Bacteria 1U6J3@1239,28VMF@1,2ZHPK@2,3F80P@33958,4IGBM@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000115 797515.HMPREF9103_00567 2.6e-187 661.4 Bacilli Bacteria 1V7SE@1239,4HJQZ@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 gnl|extdb|FAM1079-i1-1.1_000116 797515.HMPREF9103_00566 3.7e-131 474.2 Lactobacillaceae Bacteria 1V7SE@1239,3F9MC@33958,4HJQZ@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 gnl|extdb|FAM1079-i1-1.1_000117 797515.HMPREF9103_00565 5.1e-146 523.9 Lactobacillaceae psaA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FC74@33958,4HE71@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family gnl|extdb|FAM1079-i1-1.1_000119 797515.HMPREF9103_00561 2.3e-113 414.8 Lactobacillaceae ycaC Bacteria 1V7WN@1239,3F4WV@33958,4HIYX@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family gnl|extdb|FAM1079-i1-1.1_000120 797515.HMPREF9103_00560 1.9e-256 891.3 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids gnl|extdb|FAM1079-i1-1.1_000121 797515.HMPREF9103_00559 6.6e-176 623.2 Lactobacillaceae 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_000122 797515.HMPREF9103_00558 8.4e-113 412.9 Lactobacillaceae XK27_02070 ko:K07078 ko00000 Bacteria 1V1CR@1239,3F576@33958,4HD6W@91061,COG3560@1,COG3560@2 NA|NA|NA S Nitroreductase family gnl|extdb|FAM1079-i1-1.1_000123 1071400.LBUCD034_0228 1.1e-282 978.8 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM1079-i1-1.1_000124 797515.HMPREF9103_00555 3.1e-186 657.5 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta gnl|extdb|FAM1079-i1-1.1_000125 797515.HMPREF9103_00553 3.4e-152 544.3 Lactobacillaceae pheA 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDN@1239,3F57E@33958,4HA96@91061,COG0077@1,COG0077@2 NA|NA|NA E Prephenate dehydratase gnl|extdb|FAM1079-i1-1.1_000126 797515.HMPREF9103_00552 8.5e-195 686.0 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid gnl|extdb|FAM1079-i1-1.1_000127 797515.HMPREF9103_00551 2.1e-143 515.0 Lactobacillaceae tcyA ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 Bacteria 1UFZS@1239,3FC54@33958,4HD9I@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family gnl|extdb|FAM1079-i1-1.1_000128 797515.HMPREF9103_00550 1.1e-133 482.6 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10010 ko02010,map02010 M00234,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14 Bacteria 1TNYD@1239,3F4YF@33958,4HUHS@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000129 797515.HMPREF9103_00549 2.5e-116 424.9 Lactobacillaceae tcyB GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0033229,GO:0034220,GO:0042883,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098655,GO:0098656,GO:1901682,GO:1902475,GO:1903712,GO:1903825,GO:1905039 ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 iYO844.BSU03600 Bacteria 1TPQ8@1239,3F4QR@33958,4H9N1@91061,COG0765@1,COG0765@2 NA|NA|NA E ABC transporter gnl|extdb|FAM1079-i1-1.1_000130 797515.HMPREF9103_00548 1.1e-74 285.8 Lactobacillaceae ypeA 2.3.1.1 ko:K03826,ko:K22477 ko00220,ko01210,ko01230,map00220,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4GU@1239,3F6UT@33958,4HQNT@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_000131 1423743.JCM14108_1266 3.3e-154 551.2 Lactobacillaceae 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_000132 797515.HMPREF9103_00545 5.6e-217 760.0 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F5BA@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II gnl|extdb|FAM1079-i1-1.1_000133 797515.HMPREF9103_00544 2.2e-218 764.6 Lactobacillaceae ko:K01436 ko00000,ko01000,ko01002 Bacteria 1TPD7@1239,3FC42@33958,4H9WQ@91061,COG1473@1,COG1473@2 NA|NA|NA E Peptidase family M20/M25/M40 gnl|extdb|FAM1079-i1-1.1_000134 797515.HMPREF9103_00543 2.6e-244 850.9 Lactobacillaceae 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 1TQZN@1239,3F4I0@33958,4HTHM@91061,COG2873@1,COG2873@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme gnl|extdb|FAM1079-i1-1.1_000135 797515.HMPREF9103_00542 4.5e-205 720.3 Lactobacillaceae mdh 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 R02935,R02936 RC00169 ko00000,ko00001,ko01000 Bacteria 1TR0Z@1239,3F4JZ@33958,4HB6X@91061,COG2055@1,COG2055@2 NA|NA|NA C Belongs to the LDH2 MDH2 oxidoreductase family gnl|extdb|FAM1079-i1-1.1_000136 797515.HMPREF9103_00541 1.4e-192 678.7 Lactobacillaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UP5R@1239,3F5HB@33958,4HIPS@91061,COG0715@1,COG0715@2 NA|NA|NA P NMT1-like family gnl|extdb|FAM1079-i1-1.1_000137 797515.HMPREF9103_00540 2.2e-142 511.5 Lactobacillaceae ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00436 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 Bacteria 1TRM6@1239,3FC3U@33958,4HAJC@91061,COG1116@1,COG1116@2 NA|NA|NA P ABC transporter gnl|extdb|FAM1079-i1-1.1_000139 1423743.JCM14108_1254 6.9e-179 633.3 Lactobacillaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1TPI2@1239,3F4DK@33958,4HDP6@91061,COG0715@1,COG0715@2 NA|NA|NA P NMT1-like family gnl|extdb|FAM1079-i1-1.1_000140 797515.HMPREF9103_00536 4.6e-216 756.9 Lactobacillaceae metC1 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine gnl|extdb|FAM1079-i1-1.1_000141 797515.HMPREF9103_01788 2.7e-180 637.9 Lactobacillaceae htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1TP23@1239,3F40Z@33958,4HB11@91061,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family gnl|extdb|FAM1079-i1-1.1_000142 797515.HMPREF9103_01787 1.1e-87 329.3 Lactobacillaceae lemA ko:K03744 ko00000 Bacteria 1V3Z0@1239,3FCF0@33958,4HH6X@91061,COG1704@1,COG1704@2 NA|NA|NA S LemA family gnl|extdb|FAM1079-i1-1.1_000143 797515.HMPREF9103_01786 1.3e-192 679.1 Lactobacillaceae dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase gnl|extdb|FAM1079-i1-1.1_000144 511437.Lbuc_0172 1.3e-225 788.9 Lactobacillaceae gdhA 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 1TP45@1239,3F4DS@33958,4HAEI@91061,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family gnl|extdb|FAM1079-i1-1.1_000145 797515.HMPREF9103_01783 1.2e-247 862.1 Lactobacillaceae lmrB ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000146 797515.HMPREF9103_01782 5.3e-228 796.6 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM1079-i1-1.1_000147 797515.HMPREF9103_01781 1.1e-113 416.0 Lactobacillaceae yviA Bacteria 1TPNF@1239,3F4F3@33958,4HF15@91061,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) gnl|extdb|FAM1079-i1-1.1_000148 797515.HMPREF9103_01780 7.2e-53 213.0 Lactobacillaceae Bacteria 1W12G@1239,2C9NT@1,341TS@2,3FC2I@33958,4HXZV@91061 NA|NA|NA S Protein of unknown function (DUF3290) gnl|extdb|FAM1079-i1-1.1_000078 797515.HMPREF9103_02378 1.2e-25 121.7 Lactobacillaceae Bacteria 1U7UP@1239,2BWXC@1,30BB8@2,3FA76@33958,4IHS2@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000081 797515.HMPREF9103_02375 1.1e-133 482.6 Lactobacillaceae Bacteria 1V23Q@1239,3F594@33958,4HG26@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM1079-i1-1.1_000099 797515.HMPREF9103_02355 1.4e-43 181.8 Lactobacillaceae Bacteria 1U6T7@1239,29PN0@1,30AK6@2,3F8G4@33958,4IGKZ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000104 797515.HMPREF9103_02349 1.7e-300 1037.7 Lactobacillaceae abfA 3.2.1.55 ko:K01209 ko00520,map00520 R01762 ko00000,ko00001,ko01000 GH51 Bacteria 1TRY9@1239,3F5AH@33958,4HAZ7@91061,COG3534@1,COG3534@2 NA|NA|NA G Alpha-L-arabinofuranosidase C-terminus gnl|extdb|FAM1079-i1-1.1_000118 1423743.JCM14108_1280 4.4e-99 367.5 Lactobacillaceae 3.2.1.96,3.5.1.28 ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 R04112 RC00064,RC00141 ko00000,ko00001,ko01000 GH73 Bacteria 1V3MY@1239,3F4BU@33958,4HBWG@91061,COG5632@1,COG5632@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase gnl|extdb|FAM1079-i1-1.1_000138 797515.HMPREF9103_00539 2e-164 585.1 Lactobacillaceae ssuC2 ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1TQ26@1239,3F4W8@33958,4HCJ7@91061,COG0600@1,COG0600@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM1079-i1-1.1_000152 525318.HMPREF0497_2238 1.1e-294 1018.8 Lactobacillaceae mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPGK@1239,3F3PK@33958,4HB34@91061,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex gnl|extdb|FAM1079-i1-1.1_000153 797515.HMPREF9103_02794 2.4e-104 384.8 Lactobacillaceae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V3KF@1239,3F42W@33958,4HHI5@91061,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB gnl|extdb|FAM1079-i1-1.1_000154 797515.HMPREF9103_02793 2.5e-189 667.9 Lactobacillaceae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TR47@1239,3F47S@33958,4HBMW@91061,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing gnl|extdb|FAM1079-i1-1.1_000155 797515.HMPREF9103_02792 4.6e-207 726.9 Lactobacillaceae queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 1TPKD@1239,3F3VG@33958,4H9PT@91061,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) gnl|extdb|FAM1079-i1-1.1_000156 797515.HMPREF9103_02791 3.1e-225 787.3 Lactobacillaceae tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 1TNZ4@1239,3F43F@33958,4HCNM@91061,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) gnl|extdb|FAM1079-i1-1.1_000157 797515.HMPREF9103_02790 3.5e-33 147.9 Lactobacillaceae yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEMC@1239,3F7EY@33958,4HNK0@91061,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase gnl|extdb|FAM1079-i1-1.1_000158 797515.HMPREF9103_02789 1.7e-204 718.4 Lactobacillaceae dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F44N@33958,4HADJ@91061,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII gnl|extdb|FAM1079-i1-1.1_000159 797515.HMPREF9103_02788 2.1e-179 634.8 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F4FC@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain protein gnl|extdb|FAM1079-i1-1.1_000160 797515.HMPREF9103_02787 1.8e-240 838.2 Lactobacillaceae cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K18692 ko00000,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F4FQ@33958,4HA98@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures gnl|extdb|FAM1079-i1-1.1_000161 525318.HMPREF0497_2247 0.0 1585.1 Lactobacillaceae alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPK6@1239,3F3QS@33958,4H9XC@91061,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain gnl|extdb|FAM1079-i1-1.1_000162 797515.HMPREF9103_02783 2.9e-47 194.1 Lactobacillaceae yrzL Bacteria 1VAC4@1239,3F7EG@33958,4HKD0@91061,COG4472@1,COG4472@2 NA|NA|NA S Belongs to the UPF0297 family gnl|extdb|FAM1079-i1-1.1_000163 797515.HMPREF9103_02782 8e-73 279.6 Lactobacillaceae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1V6ER@1239,3F6NI@33958,4HH04@91061,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA gnl|extdb|FAM1079-i1-1.1_000164 797515.HMPREF9103_02781 9.9e-55 219.2 Lactobacillaceae yrzB Bacteria 1VAPW@1239,3F6X3@33958,4HKV7@91061,COG3906@1,COG3906@2 NA|NA|NA S Belongs to the UPF0473 family gnl|extdb|FAM1079-i1-1.1_000165 797515.HMPREF9103_02780 2.3e-41 174.5 Lactobacillaceae zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K09888 ko00000,ko03036 Bacteria 1VNMD@1239,3FB5J@33958,4I1GY@91061,COG3027@1,COG3027@2 NA|NA|NA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division gnl|extdb|FAM1079-i1-1.1_000166 797515.HMPREF9103_02779 0.0 1469.5 Lactobacillaceae mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TP5W@1239,3F4DX@33958,4H9NZ@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity gnl|extdb|FAM1079-i1-1.1_000167 797515.HMPREF9103_02778 1.7e-53 214.9 Lactobacillaceae trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F6Y3@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family gnl|extdb|FAM1079-i1-1.1_000168 797515.HMPREF9103_02777 4.5e-94 350.5 Lactobacillaceae yslB Bacteria 1VD7N@1239,3F7ZI@33958,4HKV3@91061,COG1719@1,COG1719@2 NA|NA|NA S Protein of unknown function (DUF2507) gnl|extdb|FAM1079-i1-1.1_000169 797515.HMPREF9103_02776 1.1e-150 539.3 Lactobacillaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 1TPPR@1239,3F446@33958,4HA46@91061,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis gnl|extdb|FAM1079-i1-1.1_000170 797515.HMPREF9103_02775 2e-106 391.7 Lactobacillaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1V6RN@1239,3F3KD@33958,4HCP6@91061,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions gnl|extdb|FAM1079-i1-1.1_000171 797515.HMPREF9103_02774 8.2e-93 346.3 Lactobacillaceae ko:K07095 ko00000 Bacteria 1VA0U@1239,3F73R@33958,4HM24@91061,COG0622@1,COG0622@2 NA|NA|NA S Phosphoesterase gnl|extdb|FAM1079-i1-1.1_000172 797515.HMPREF9103_02773 3.5e-91 340.9 Lactobacillaceae ykuL Bacteria 1V9HN@1239,3F678@33958,4HH3X@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain gnl|extdb|FAM1079-i1-1.1_000173 797515.HMPREF9103_02772 1.8e-143 515.4 Lactobacillaceae ykuT GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1TR9Z@1239,3F49U@33958,4HCB8@91061,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel gnl|extdb|FAM1079-i1-1.1_000175 797515.HMPREF9103_02770 7.2e-30 137.1 Lactobacillaceae Bacteria 1U70A@1239,2DKTG@1,30AR7@2,3F8T5@33958,4IGUM@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000176 797515.HMPREF9103_02769 1e-209 735.7 Lactobacillaceae pepQ 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ6R@1239,3F3X5@33958,4HA5I@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain gnl|extdb|FAM1079-i1-1.1_000177 797515.HMPREF9103_02768 6.6e-179 633.3 Lactobacillaceae ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4AA@33958,4H9NG@91061,COG1609@1,COG1609@2 NA|NA|NA K catabolite control protein A gnl|extdb|FAM1079-i1-1.1_000178 797515.HMPREF9103_02767 1.2e-132 479.2 Lactobacillaceae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 1TPP5@1239,3F4WF@33958,4H9WJ@91061,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein gnl|extdb|FAM1079-i1-1.1_000179 797515.HMPREF9103_02766 2.9e-179 634.4 Lactobacillaceae comGA ko:K02243 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1TPGE@1239,3F4HY@33958,4HB0C@91061,COG2804@1,COG2804@2 NA|NA|NA NU Type II IV secretion system protein gnl|extdb|FAM1079-i1-1.1_000180 797515.HMPREF9103_02764 1.2e-117 429.9 Lactobacillaceae comGB ko:K02244 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1U00C@1239,3F3S9@33958,4HGUA@91061,COG1459@1,COG1459@2 NA|NA|NA NU type II secretion system gnl|extdb|FAM1079-i1-1.1_000181 797515.HMPREF9103_02763 2.9e-51 207.6 Lactobacillaceae comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1VFI9@1239,3F7ZC@33958,4HNNT@91061,COG4537@1,COG4537@2 NA|NA|NA U competence protein ComGC gnl|extdb|FAM1079-i1-1.1_000182 1071400.LBUCD034_1084 1.1e-24 119.8 Lactobacillaceae ko:K02246 M00429 ko00000,ko00002,ko02044 Bacteria 1TZC0@1239,2DJI7@1,30682@2,3F8AE@33958,4I8K1@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000183 797515.HMPREF9103_02762 8.3e-24 115.5 Lactobacillaceae Bacteria 1U759@1239,29PWW@1,30AV7@2,3F8ZY@33958,4IGZY@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000184 797515.HMPREF9103_02761 1.2e-76 292.4 Lactobacillaceae ko:K02248 M00429 ko00000,ko00002,ko02044 Bacteria 1U6HH@1239,29PF0@1,30AD6@2,3F7XR@33958,4IG9U@91061 NA|NA|NA S Putative Competence protein ComGF gnl|extdb|FAM1079-i1-1.1_000185 797515.HMPREF9103_02759 1.8e-184 651.7 Lactobacillaceae ytxK 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TRIQ@1239,3F4CI@33958,4H9SE@91061,COG0827@1,COG0827@2 NA|NA|NA L N-6 DNA Methylase gnl|extdb|FAM1079-i1-1.1_000186 525318.HMPREF0497_2273 1.8e-207 728.4 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction gnl|extdb|FAM1079-i1-1.1_000187 797515.HMPREF9103_02756 7.8e-247 859.4 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM1079-i1-1.1_000188 797515.HMPREF9103_02755 1.3e-116 425.6 Lactobacillaceae Bacteria 1V35X@1239,3FBJA@33958,4IQV1@91061,COG4186@1,COG4186@2 NA|NA|NA S Calcineurin-like phosphoesterase gnl|extdb|FAM1079-i1-1.1_000189 797515.HMPREF9103_02754 8.9e-267 925.6 Lactobacillaceae yunD 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TQCW@1239,3F4ZD@33958,4HAUC@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family gnl|extdb|FAM1079-i1-1.1_000190 797515.HMPREF9103_02753 3.5e-91 341.3 Lactobacillaceae yutD Bacteria 1VA85@1239,3F66P@33958,4HKF7@91061,COG4470@1,COG4470@2 NA|NA|NA S Protein of unknown function (DUF1027) gnl|extdb|FAM1079-i1-1.1_000191 797515.HMPREF9103_02752 3.4e-143 514.2 Lactobacillaceae nagD 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGM@1239,3F49D@33958,4HA3R@91061,COG0647@1,COG0647@2 NA|NA|NA G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro gnl|extdb|FAM1079-i1-1.1_000192 797515.HMPREF9103_02751 3.1e-113 414.5 Lactobacillaceae Bacteria 1VGZ1@1239,3FBK9@33958,4HNTM@91061,COG4478@1,COG4478@2 NA|NA|NA S Protein of unknown function (DUF1461) gnl|extdb|FAM1079-i1-1.1_000193 797515.HMPREF9103_02750 1.6e-25 121.3 Lactobacillaceae ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VKBQ@1239,3F8BW@33958,4HRGW@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain gnl|extdb|FAM1079-i1-1.1_000194 797515.HMPREF9103_02749 2.7e-41 174.1 Lactobacillaceae Bacteria 1U6H6@1239,2CAB0@1,30ACY@2,3F7X2@33958,4IG9H@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000195 797515.HMPREF9103_02748 1.8e-220 771.5 Lactobacillaceae mvaS 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4K@1239,3F425@33958,4HA67@91061,COG3425@1,COG3425@2 NA|NA|NA I Hydroxymethylglutaryl-CoA synthase gnl|extdb|FAM1079-i1-1.1_000196 797515.HMPREF9103_02747 7.2e-115 419.9 Lactobacillaceae lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1TQ3H@1239,3F3JG@33958,4HBHA@91061,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair gnl|extdb|FAM1079-i1-1.1_000197 797515.HMPREF9103_02746 2.1e-42 177.9 Lactobacillaceae ynzC Bacteria 1VEKJ@1239,3F87S@33958,4HNIB@91061,COG4224@1,COG4224@2 NA|NA|NA S UPF0291 protein gnl|extdb|FAM1079-i1-1.1_000198 797515.HMPREF9103_02745 1e-15 89.0 Lactobacillaceae yneF ko:K09976 ko00000 Bacteria 1VEJC@1239,3FCDQ@33958,4HNN9@91061,COG3763@1,COG3763@2 NA|NA|NA S UPF0154 protein gnl|extdb|FAM1079-i1-1.1_000199 797515.HMPREF9103_02744 5.4e-118 430.3 Lactobacillaceae plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1U8N2@1239,3F4QB@33958,4HDQR@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase gnl|extdb|FAM1079-i1-1.1_000200 797515.HMPREF9103_02743 3.7e-134 484.2 Lactobacillaceae yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 ko00000,ko01000,ko03016 Bacteria 1TQ25@1239,3F4C5@33958,4HA8W@91061,COG4123@1,COG4123@2 NA|NA|NA L Methyltransferase small domain gnl|extdb|FAM1079-i1-1.1_000201 797515.HMPREF9103_02742 1.4e-43 181.8 Lactobacillaceae yazA ko:K07461 ko00000 Bacteria 1VEZF@1239,3F7G2@33958,4HNHJ@91061,COG2827@1,COG2827@2 NA|NA|NA L GIY-YIG catalytic domain protein gnl|extdb|FAM1079-i1-1.1_000202 797515.HMPREF9103_02741 4.2e-186 657.1 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_000203 797515.HMPREF9103_02740 2.5e-135 488.0 Lactobacillaceae ko:K07025 ko00000 Bacteria 1V5P7@1239,3F5CR@33958,4HHGY@91061,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase gnl|extdb|FAM1079-i1-1.1_000204 797515.HMPREF9103_02739 1.4e-139 502.3 Lactobacillaceae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPNA@1239,3F3M1@33958,4H9N5@91061,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family gnl|extdb|FAM1079-i1-1.1_000205 797515.HMPREF9103_02738 8.4e-154 549.7 Lactobacillaceae tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1TPFJ@1239,3F459@33958,4HBDV@91061,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome gnl|extdb|FAM1079-i1-1.1_000206 797515.HMPREF9103_02736 5.3e-130 470.3 Lactobacillaceae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1TPXN@1239,3F42J@33958,4H9UB@91061,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP gnl|extdb|FAM1079-i1-1.1_000207 797515.HMPREF9103_02735 4.1e-93 347.4 Lactobacillaceae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1V1F2@1239,3F4X2@33958,4HFSH@91061,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another gnl|extdb|FAM1079-i1-1.1_000208 525318.HMPREF0497_2296 7.2e-69 266.5 Lactobacillaceae Bacteria 1U5UH@1239,2BZ0D@1,309WH@2,3F6II@33958,4IFIA@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000209 797515.HMPREF9103_02733 3.7e-145 520.8 Lactobacillaceae uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1TQTS@1239,3F42M@33958,4HA37@91061,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids gnl|extdb|FAM1079-i1-1.1_000210 525318.HMPREF0497_2298 2e-122 445.3 Lactobacillaceae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 1UPNB@1239,3F4AF@33958,4IV81@91061,COG0575@1,COG0575@2 NA|NA|NA I Belongs to the CDS family gnl|extdb|FAM1079-i1-1.1_000211 797515.HMPREF9103_02731 4.4e-228 797.0 Lactobacillaceae rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399,ko:K11749,ko:K16922 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPMC@1239,3F3TM@33958,4HAQ5@91061,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease gnl|extdb|FAM1079-i1-1.1_000212 797515.HMPREF9103_02730 0.0 1101.7 Lactobacillaceae proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1TRBV@1239,3F44A@33958,4H9NN@91061,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS gnl|extdb|FAM1079-i1-1.1_000214 797515.HMPREF9103_02728 1.1e-78 299.3 Lactobacillaceae rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1V6KT@1239,3F6GZ@33958,4HH88@91061,COG0779@1,COG0779@2 NA|NA|NA J Required for maturation of 30S ribosomal subunits gnl|extdb|FAM1079-i1-1.1_000215 797515.HMPREF9103_02727 4.3e-199 700.7 Lactobacillaceae nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600,ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021 Bacteria 1TPB3@1239,3F3KZ@33958,4HA7F@91061,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination gnl|extdb|FAM1079-i1-1.1_000216 797515.HMPREF9103_02726 5.2e-47 193.4 Lactobacillaceae ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria 1VEJS@1239,3F7E2@33958,4HKBY@91061,COG2740@1,COG2740@2 NA|NA|NA K Protein of unknown function (DUF448) gnl|extdb|FAM1079-i1-1.1_000217 797515.HMPREF9103_02725 4.8e-51 206.8 Lactobacillaceae ylxQ ko:K07590,ko:K07742 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEYG@1239,3F7ZK@33958,4HNY7@91061,COG1358@1,COG1358@2 NA|NA|NA J ribosomal protein gnl|extdb|FAM1079-i1-1.1_000218 797515.HMPREF9103_02723 0.0 1159.1 Lactobacillaceae infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1TPAI@1239,3F3JV@33958,4HA8S@91061,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gnl|extdb|FAM1079-i1-1.1_000219 797515.HMPREF9103_02722 3.8e-57 227.3 Lactobacillaceae rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1VA0P@1239,3F6WZ@33958,4HII1@91061,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA gnl|extdb|FAM1079-i1-1.1_000220 797515.HMPREF9103_02721 5.4e-172 610.1 Lactobacillaceae truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 ko00000,ko01000,ko03000,ko03016 iSB619.SA_RS06305 Bacteria 1TP9Y@1239,3F3NX@33958,4HA9X@91061,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs gnl|extdb|FAM1079-i1-1.1_000221 797515.HMPREF9103_02720 4.2e-183 647.1 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1TPKS@1239,3F3TG@33958,4H9KE@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family gnl|extdb|FAM1079-i1-1.1_000224 797515.HMPREF9103_02717 0.0 1107.0 Lactobacillaceae dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TP1J@1239,3F48C@33958,4HA9S@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein gnl|extdb|FAM1079-i1-1.1_000225 797515.HMPREF9103_02716 4.4e-195 687.2 Lactobacillaceae dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 1TP00@1239,3F490@33958,4H9KA@91061,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins gnl|extdb|FAM1079-i1-1.1_000226 797515.HMPREF9103_02715 0.0 1196.4 Lactobacillaceae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1TP0G@1239,3F3Z1@33958,4HASA@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner gnl|extdb|FAM1079-i1-1.1_000227 797515.HMPREF9103_02714 3.7e-70 270.8 Lactobacillaceae Bacteria 1U5U2@1239,2DKM2@1,309W8@2,3F6I8@33958,4IFI0@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000228 797515.HMPREF9103_02713 1.4e-68 265.4 Lactobacillaceae Bacteria 1U5X7@1239,29NZX@1,309Y2@2,3F6N0@33958,4IFKM@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000229 797515.HMPREF9103_02712 2.6e-58 231.1 Lactobacillaceae Bacteria 1W026@1239,2FCQV@1,344U2@2,3F7FM@33958,4HZ7F@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000230 797515.HMPREF9103_02711 1e-176 625.9 Lactobacillaceae prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1TPKI@1239,3F47Z@33958,4HAMF@91061,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase gnl|extdb|FAM1079-i1-1.1_000231 797515.HMPREF9103_02710 3.4e-132 477.6 Lactobacillaceae rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1V7BD@1239,3FBME@33958,4IR59@91061,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit gnl|extdb|FAM1079-i1-1.1_000232 525318.HMPREF0497_2399 0.0 1406.0 Lactobacillaceae relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 iHN637.CLJU_RS16615,iYO844.BSU27600 Bacteria 1TNYZ@1239,3F44F@33958,4HBX7@91061,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance gnl|extdb|FAM1079-i1-1.1_000233 797515.HMPREF9103_02707 1.1e-77 295.8 Lactobacillaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,3F6GK@33958,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality gnl|extdb|FAM1079-i1-1.1_000234 797515.HMPREF9103_02706 6.4e-119 433.3 Lactobacillaceae 3.1.3.18 ko:K01091,ko:K07025 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V9GF@1239,3FBP2@33958,4HJ85@91061,COG0546@1,COG0546@2 NA|NA|NA S HAD-hyrolase-like gnl|extdb|FAM1079-i1-1.1_000235 797515.HMPREF9103_02705 4.9e-167 593.6 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1V1VZ@1239,3FCE0@33958,4HGP7@91061,COG3001@1,COG3001@2 NA|NA|NA G Fructosamine kinase gnl|extdb|FAM1079-i1-1.1_000236 797515.HMPREF9103_02704 3.1e-145 521.2 Lactobacillaceae lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1UYPW@1239,3F4F4@33958,4HBVT@91061,COG0860@1,COG0860@2,COG3103@1,COG4991@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase gnl|extdb|FAM1079-i1-1.1_000237 797515.HMPREF9103_02703 5.6e-247 859.8 Lactobacillaceae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP3D@1239,3F3M3@33958,4HAM2@91061,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase gnl|extdb|FAM1079-i1-1.1_000238 797515.HMPREF9103_02702 0.0 1190.6 Lactobacillaceae aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,3F4PE@33958,4HACD@91061,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) gnl|extdb|FAM1079-i1-1.1_000239 797515.HMPREF9103_02701 2.5e-158 564.7 Lactobacillaceae yitT Bacteria 1TRBT@1239,3F3PH@33958,4HBPR@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 gnl|extdb|FAM1079-i1-1.1_000240 797515.HMPREF9103_02700 8.6e-223 779.2 Lactobacillaceae tagB 2.7.8.14,2.7.8.44,2.7.8.47 ko:K18704,ko:K21285 R11558,R11614,R11621 RC00078 ko00000,ko01000 iYO844.BSU35760 Bacteria 1TSTN@1239,3F456@33958,4HBID@91061,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase gnl|extdb|FAM1079-i1-1.1_000241 797515.HMPREF9103_02699 1.1e-152 545.8 Lactobacillaceae tagG GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0033036,GO:0051179,GO:0051234,GO:0071702,GO:1901264 ko:K09690,ko:K09692 ko02010,map02010 M00250,M00251 ko00000,ko00001,ko00002,ko02000 3.A.1.103,3.A.1.104 Bacteria 1TQZF@1239,3F4FP@33958,4HB9R@91061,COG1682@1,COG1682@2 NA|NA|NA U Transport permease protein gnl|extdb|FAM1079-i1-1.1_000242 797515.HMPREF9103_02698 2e-238 831.2 Lactobacillaceae tagF1 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.8.12,2.7.8.45 ko:K09809,ko:K21591 R11612 ko00000,ko01000 Bacteria 1TP75@1239,3FC1F@33958,4HEW4@91061,COG1887@1,COG1887@2 NA|NA|NA M glycerophosphotransferase gnl|extdb|FAM1079-i1-1.1_000243 797515.HMPREF9103_02697 2.8e-176 624.4 Lactobacillaceae nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP1D@1239,3F42I@33958,4HB4F@91061,COG0648@1,COG0648@2 NA|NA|NA L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin gnl|extdb|FAM1079-i1-1.1_000244 797515.HMPREF9103_02696 4.2e-147 527.3 Lactobacillaceae yqfL 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 1TPG0@1239,3F3WK@33958,4HB0Q@91061,COG1806@1,COG1806@2 NA|NA|NA F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation gnl|extdb|FAM1079-i1-1.1_000245 1071400.LBUCD034_1146 4.3e-23 113.2 Lactobacillaceae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEHU@1239,3F81Y@33958,4HNPV@91061,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family gnl|extdb|FAM1079-i1-1.1_000246 797515.HMPREF9103_02694 7.7e-71 273.1 Lactobacillaceae yqeY ko:K09117 ko00000 Bacteria 1V6F2@1239,3F6I0@33958,4HIQP@91061,COG1610@1,COG1610@2 NA|NA|NA S YqeY-like protein gnl|extdb|FAM1079-i1-1.1_000247 797515.HMPREF9103_02693 2.3e-176 624.8 Lactobacillaceae phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1TP35@1239,3F4E7@33958,4HBD5@91061,COG1702@1,COG1702@2 NA|NA|NA T phosphate starvation-inducible protein PhoH gnl|extdb|FAM1079-i1-1.1_000248 797515.HMPREF9103_02692 1.2e-85 322.4 Lactobacillaceae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1V6BU@1239,3F516@33958,4HIIE@91061,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA gnl|extdb|FAM1079-i1-1.1_000249 797515.HMPREF9103_02691 3.3e-65 254.2 Lactobacillaceae dgkA 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2369,iSB619.SA_RS07900 Bacteria 1VEGR@1239,3F7DC@33958,4HNKN@91061,COG0818@1,COG0818@2 NA|NA|NA M Diacylglycerol kinase gnl|extdb|FAM1079-i1-1.1_000250 797515.HMPREF9103_02690 1.2e-166 592.4 Lactobacillaceae era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1TP3R@1239,3F3WQ@33958,4H9WF@91061,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism gnl|extdb|FAM1079-i1-1.1_000251 797515.HMPREF9103_02689 1.2e-145 522.3 Lactobacillaceae recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,3F56P@33958,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination gnl|extdb|FAM1079-i1-1.1_000252 797515.HMPREF9103_02687 5.7e-177 626.7 Lactobacillaceae glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1TPW8@1239,3F3T8@33958,4HBCF@91061,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit gnl|extdb|FAM1079-i1-1.1_000253 797515.HMPREF9103_02686 0.0 1358.2 Lactobacillaceae glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1TNZ7@1239,3F4G8@33958,4H9NT@91061,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit gnl|extdb|FAM1079-i1-1.1_000254 797515.HMPREF9103_02684 6.8e-299 1032.7 Lactobacillaceae dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQ0X@1239,3F3N1@33958,4HAG2@91061,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication gnl|extdb|FAM1079-i1-1.1_000255 525318.HMPREF0497_2422 8.9e-191 672.9 Lactobacillaceae sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,3F4CF@33958,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth gnl|extdb|FAM1079-i1-1.1_000256 797515.HMPREF9103_02681 1.1e-124 452.6 Lactobacillaceae trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 ko00000,ko01000,ko03016 Bacteria 1V3I4@1239,3F4GT@33958,4HHIM@91061,COG2384@1,COG2384@2 NA|NA|NA S SAM-dependent methyltransferase gnl|extdb|FAM1079-i1-1.1_000257 797515.HMPREF9103_02680 5.8e-216 756.5 Lactobacillaceae yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ27@1239,3F3ZD@33958,4H9NY@91061,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family gnl|extdb|FAM1079-i1-1.1_000258 797515.HMPREF9103_02679 1.8e-234 818.1 Lactobacillaceae pepT GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides gnl|extdb|FAM1079-i1-1.1_000259 525318.HMPREF0497_2426 0.0 1408.7 Lactobacillaceae clpB GO:0003674,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0042802,GO:0043170,GO:0044238,GO:0071704,GO:1901564 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE gnl|extdb|FAM1079-i1-1.1_000260 797515.HMPREF9103_02676 2e-171 608.2 Lactobacillaceae Bacteria 1TRM1@1239,3F5QC@33958,4HA1B@91061,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 gnl|extdb|FAM1079-i1-1.1_000262 797515.HMPREF9103_02674 0.0 2167.1 Lactobacillaceae dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPYG@1239,3F4AM@33958,4H9T3@91061,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase gnl|extdb|FAM1079-i1-1.1_000263 797515.HMPREF9103_02673 0.0 1129.0 Lactobacillaceae pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 1TPGG@1239,3F3JU@33958,4H9VY@91061,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family gnl|extdb|FAM1079-i1-1.1_000264 797515.HMPREF9103_02672 1.5e-163 582.0 Lactobacillaceae cvfB ko:K00243 ko00000 Bacteria 1TQ1Z@1239,3F44W@33958,4HDAZ@91061,COG2996@1,COG2996@2 NA|NA|NA S S1 domain gnl|extdb|FAM1079-i1-1.1_000265 797515.HMPREF9103_02671 3.2e-164 584.3 Lactobacillaceae xerD ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3F3V9@33958,4HAEX@91061,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD gnl|extdb|FAM1079-i1-1.1_000266 797515.HMPREF9103_02670 1.5e-64 251.9 Lactobacillaceae ribT ko:K02859 ko00000 Bacteria 1VAD7@1239,3F7QC@33958,4HKR2@91061,COG0454@1,COG0456@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases gnl|extdb|FAM1079-i1-1.1_000267 797515.HMPREF9103_02669 2e-135 488.4 Lactobacillaceae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1TRW3@1239,3F4FS@33958,4HA6Q@91061,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves gnl|extdb|FAM1079-i1-1.1_000269 797515.HMPREF9103_02667 2.8e-131 474.6 Lactobacillaceae rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,3F402@33958,4H9MU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family gnl|extdb|FAM1079-i1-1.1_000270 797515.HMPREF9103_02666 6.2e-97 360.1 Lactobacillaceae Bacteria 1V4BW@1239,3F4HD@33958,4HHFT@91061,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins gnl|extdb|FAM1079-i1-1.1_000271 797515.HMPREF9103_02665 1.5e-192 678.7 Lactobacillaceae ypbB 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU9@1239,3F45N@33958,4HJ71@91061,COG4955@1,COG4955@2 NA|NA|NA S Helix-turn-helix domain gnl|extdb|FAM1079-i1-1.1_000272 797515.HMPREF9103_02664 3.8e-276 956.8 Lactobacillaceae recQ1 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ gnl|extdb|FAM1079-i1-1.1_000274 797515.HMPREF9103_02662 3.2e-116 424.5 Lactobacillaceae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1V3IA@1239,3F3W4@33958,4HFZE@91061,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily gnl|extdb|FAM1079-i1-1.1_000275 797515.HMPREF9103_02661 2.8e-211 741.1 Lactobacillaceae rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1TQ9N@1239,3F4DQ@33958,4H9PX@91061,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 gnl|extdb|FAM1079-i1-1.1_000276 797515.HMPREF9103_02660 1.6e-249 868.2 Lactobacillaceae der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 1TPNM@1239,3F4V0@33958,4HAJ6@91061,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis gnl|extdb|FAM1079-i1-1.1_000277 797515.HMPREF9103_02658 2.5e-40 171.0 Lactobacillaceae hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1V9XQ@1239,3F6YN@33958,4HKF2@91061,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions gnl|extdb|FAM1079-i1-1.1_000278 797515.HMPREF9103_02657 2.2e-216 758.1 Lactobacillaceae Bacteria 1TT97@1239,3F3ND@33958,4HAIA@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat protein gnl|extdb|FAM1079-i1-1.1_000279 797515.HMPREF9103_02656 4.7e-160 570.5 Lactobacillaceae ypjC Bacteria 1TRAU@1239,3F44R@33958,4H9UY@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 gnl|extdb|FAM1079-i1-1.1_000280 797515.HMPREF9103_02655 8.4e-221 772.7 Lactobacillaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1TQ2A@1239,3F3VH@33958,4HB2W@91061,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate gnl|extdb|FAM1079-i1-1.1_000281 797515.HMPREF9103_02654 0.0 1228.0 Lactobacillaceae yfmR ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 1TPAX@1239,3FC7W@33958,4H9TK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000282 797515.HMPREF9103_02653 7.4e-188 662.9 Lactobacillaceae thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSIR@1239,3F3SB@33958,4H9QS@91061,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis gnl|extdb|FAM1079-i1-1.1_000283 797515.HMPREF9103_02652 6.6e-92 343.2 Lactobacillaceae folA 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 Bacteria 1VB80@1239,3F6Y4@33958,4HIGJ@91061,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis gnl|extdb|FAM1079-i1-1.1_000284 797515.HMPREF9103_02651 4.9e-151 540.4 Lactobacillaceae DegV Bacteria 1TRZ4@1239,3F4CW@33958,4HBR8@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family gnl|extdb|FAM1079-i1-1.1_000285 797515.HMPREF9103_02650 8.1e-160 569.7 Lactobacillaceae ypmR GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 Bacteria 1V1HR@1239,3F4N0@33958,4HDXS@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase gnl|extdb|FAM1079-i1-1.1_000286 525318.HMPREF0497_2455 1.3e-76 292.7 Lactobacillaceae ypmS Bacteria 1VF0K@1239,3F5K5@33958,4HIYN@91061,COG4698@1,COG4698@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2140) gnl|extdb|FAM1079-i1-1.1_000287 797515.HMPREF9103_02648 6.2e-34 149.4 Lactobacillaceae yozE Bacteria 1VFI4@1239,3FCDP@33958,4HR7P@91061,COG4479@1,COG4479@2 NA|NA|NA S Belongs to the UPF0346 family gnl|extdb|FAM1079-i1-1.1_000288 797515.HMPREF9103_02647 9.2e-161 572.8 Lactobacillaceae ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1TQGK@1239,3F3MI@33958,4HA4D@91061,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity gnl|extdb|FAM1079-i1-1.1_000289 797515.HMPREF9103_02646 3.4e-135 487.6 Lactobacillaceae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V1D6@1239,3F3JC@33958,4HB7M@91061,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids gnl|extdb|FAM1079-i1-1.1_000290 797515.HMPREF9103_02645 6.8e-164 583.2 Lactobacillaceae dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1TPP7@1239,3F41U@33958,4HGWM@91061,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA gnl|extdb|FAM1079-i1-1.1_000291 797515.HMPREF9103_02644 0.0 1379.4 Lactobacillaceae topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1TPUS@1239,3F3VS@33958,4HA6C@91061,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone gnl|extdb|FAM1079-i1-1.1_000292 797515.HMPREF9103_02643 5.2e-278 963.0 Lactobacillaceae pepD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase gnl|extdb|FAM1079-i1-1.1_000293 797515.HMPREF9103_02642 1.9e-280 971.1 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase gnl|extdb|FAM1079-i1-1.1_000294 525318.HMPREF0497_2463 2e-25 120.9 Lactobacillaceae dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1VKD5@1239,3F83T@33958,4HRBS@91061,COG1942@1,COG1942@2 NA|NA|NA G Belongs to the 4-oxalocrotonate tautomerase family gnl|extdb|FAM1079-i1-1.1_000295 797515.HMPREF9103_02640 2.3e-292 1010.7 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate gnl|extdb|FAM1079-i1-1.1_000296 797515.HMPREF9103_02639 4.2e-155 553.9 Lactobacillaceae yitU 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TREF@1239,3F47B@33958,4H9Y9@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase gnl|extdb|FAM1079-i1-1.1_000297 797515.HMPREF9103_02638 3.1e-272 943.7 Lactobacillaceae rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 ko00000,ko01000,ko03009 Bacteria 1TPGQ@1239,3F492@33958,4HCHQ@91061,COG0144@1,COG0144@2,COG3270@1,COG3270@2 NA|NA|NA J NOL1 NOP2 sun family protein gnl|extdb|FAM1079-i1-1.1_000298 797515.HMPREF9103_02637 1.8e-187 661.8 Lactobacillaceae fni 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQZ3@1239,3F3UY@33958,4HAMV@91061,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) gnl|extdb|FAM1079-i1-1.1_000299 797515.HMPREF9103_02636 1.2e-208 732.3 Lactobacillaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,3F3RZ@33958,4HC93@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase gnl|extdb|FAM1079-i1-1.1_000301 797515.HMPREF9103_02634 5.3e-141 507.3 Lactobacillaceae mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT5C@1239,3F3TW@33958,4HAQQ@91061,COG1577@1,COG1577@2 NA|NA|NA I mevalonate kinase gnl|extdb|FAM1079-i1-1.1_000302 797515.HMPREF9103_02633 0.0 1860.1 Lactobacillaceae dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQHQ@1239,3F4KA@33958,4HB2Y@91061,COG0847@1,COG0847@2,COG1199@1,COG1199@2 NA|NA|NA L helicase involved in DNA repair and perhaps also replication gnl|extdb|FAM1079-i1-1.1_000303 797515.HMPREF9103_02632 8.7e-87 326.2 Lactobacillaceae ypmB Bacteria 1VA2H@1239,3F4MM@33958,4HNMM@91061,COG5353@1,COG5353@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM1079-i1-1.1_000304 797515.HMPREF9103_02631 1.4e-226 792.0 Lactobacillaceae aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS06550 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM1079-i1-1.1_000305 797515.HMPREF9103_02630 1e-256 892.1 Lactobacillaceae asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,3F4EK@33958,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase gnl|extdb|FAM1079-i1-1.1_000306 797515.HMPREF9103_02629 1e-128 466.1 Lactobacillaceae dnaD ko:K02086 ko00000 Bacteria 1V283@1239,3F4FF@33958,4HFP3@91061,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein gnl|extdb|FAM1079-i1-1.1_000150 797515.HMPREF9103_02798 1.8e-150 538.5 Lactobacillaceae ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 ko:K02029,ko:K02030,ko:K09769 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TR9P@1239,3F484@33958,4HAV5@91061,COG1692@1,COG1692@2 NA|NA|NA S YmdB-like protein gnl|extdb|FAM1079-i1-1.1_000151 797515.HMPREF9103_02797 0.0 1669.1 Lactobacillaceae mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPRJ@1239,3F4A5@33958,4HA63@91061,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity gnl|extdb|FAM1079-i1-1.1_000213 797515.HMPREF9103_02729 0.0 2869.0 Lactobacillaceae polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPAG@1239,3F4AN@33958,4H9RF@91061,COG2176@1,COG2176@2 NA|NA|NA L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity gnl|extdb|FAM1079-i1-1.1_000222 797515.HMPREF9103_02719 1.7e-190 671.8 Lactobacillaceae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1TQP7@1239,3F3ST@33958,4HAX5@91061,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons gnl|extdb|FAM1079-i1-1.1_000223 797515.HMPREF9103_02718 3.4e-82 311.2 Lactobacillaceae grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1V6G2@1239,3F4DY@33958,4HIRK@91061,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ gnl|extdb|FAM1079-i1-1.1_000261 797515.HMPREF9103_02675 1.5e-31 141.7 Lactobacillaceae Bacteria 1W2U5@1239,2DGWH@1,2ZXI7@2,3F8TZ@33958,4I0PU@91061 NA|NA|NA S Protein of unknown function (DUF2929) gnl|extdb|FAM1079-i1-1.1_000268 797515.HMPREF9103_02668 2.1e-103 381.7 Lactobacillaceae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1V6HI@1239,3F5RN@33958,4HIQ0@91061,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves gnl|extdb|FAM1079-i1-1.1_000300 797515.HMPREF9103_02635 9.9e-175 619.4 Lactobacillaceae mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXR@1239,3F4B5@33958,4HAM6@91061,COG3407@1,COG3407@2 NA|NA|NA I diphosphomevalonate decarboxylase gnl|extdb|FAM1079-i1-1.1_000307 1071400.LBUCD034_1601 2.7e-42 177.6 Lactobacillaceae Bacteria 1UYND@1239,3FBNE@33958,4IRAQ@91061,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_000310 797515.HMPREF9103_01274 3.1e-110 404.4 Lactobacillaceae Bacteria 1VK84@1239,3FBWG@33958,4ITM1@91061,COG1396@1,COG1396@2 NA|NA|NA K DNA-binding helix-turn-helix protein gnl|extdb|FAM1079-i1-1.1_000312 797515.HMPREF9103_01272 3.4e-109 401.4 Lactobacillaceae ko:K07052 ko00000 Bacteria 1UYI9@1239,3F74I@33958,4I2VS@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM1079-i1-1.1_000313 797515.HMPREF9103_01271 2e-194 684.9 Lactobacillaceae adh 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F42F@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase gnl|extdb|FAM1079-i1-1.1_000315 797515.HMPREF9103_01268 1.2e-68 265.8 Lactobacillaceae pheB 5.4.99.5 ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 iYO844.BSU27910 Bacteria 1VAJ9@1239,3F6TJ@33958,4HFRC@91061,COG4492@1,COG4492@2 NA|NA|NA S Belongs to the UPF0735 family gnl|extdb|FAM1079-i1-1.1_000316 797515.HMPREF9103_01267 8.6e-170 602.8 Lactobacillaceae thrB 2.7.1.39,4.2.3.1 ko:K00872,ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R01771,R05086 RC00002,RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRWS@1239,3F44T@33958,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate gnl|extdb|FAM1079-i1-1.1_000317 797515.HMPREF9103_01266 7.1e-286 989.2 Lactobacillaceae thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 1TPR0@1239,3F3UF@33958,4H9R7@91061,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase gnl|extdb|FAM1079-i1-1.1_000318 797515.HMPREF9103_01265 2.8e-232 810.8 Lactobacillaceae hom 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06610 Bacteria 1TQ2H@1239,3F5BM@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase gnl|extdb|FAM1079-i1-1.1_000319 797515.HMPREF9103_01264 2.3e-240 837.8 Lactobacillaceae yclM 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family gnl|extdb|FAM1079-i1-1.1_000320 797515.HMPREF9103_01263 0.0 1171.8 Lactobacillaceae gph ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter gnl|extdb|FAM1079-i1-1.1_000321 46256.BBIK01000005_gene844 1.7e-299 1035.0 Leuconostocaceae rafA GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009987,GO:0010033,GO:0015925,GO:0016043,GO:0016052,GO:0016787,GO:0016798,GO:0022607,GO:0042221,GO:0043933,GO:0044085,GO:0044238,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901545,GO:1901575,GO:1901700 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,4AWNT@81850,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G Glycosyl hydrolase family 36 N-terminal domain gnl|extdb|FAM1079-i1-1.1_000322 797515.HMPREF9103_01261 8.8e-173 612.8 Lactobacillaceae scrR ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4JE@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family gnl|extdb|FAM1079-i1-1.1_000323 797515.HMPREF9103_01260 6.3e-151 540.0 Lactobacillaceae rlrG ko:K21900 ko00000,ko03000 Bacteria 1TP6T@1239,3F4VC@33958,4HC4T@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000324 797515.HMPREF9103_01259 1.5e-172 612.1 Lactobacillaceae shetA ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 2.A.16,2.A.16.1 Bacteria 1UYTE@1239,3F4I9@33958,4HIE2@91061,COG1275@1,COG1275@2 NA|NA|NA P C4-dicarboxylate transporter malic acid transport protein gnl|extdb|FAM1079-i1-1.1_000325 525318.HMPREF0497_0221 6.1e-239 833.2 Lactobacillaceae mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid gnl|extdb|FAM1079-i1-1.1_000326 797515.HMPREF9103_01256 1.3e-179 635.6 Lactobacillaceae mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQ5@1239,3F4UT@33958,4HAS6@91061,COG2040@1,COG2040@2 NA|NA|NA H homocysteine S-methyltransferase gnl|extdb|FAM1079-i1-1.1_000327 797515.HMPREF9103_01255 1.4e-155 555.8 Lactobacillaceae Bacteria 1U5G3@1239,3F9B7@33958,4I2Y5@91061,COG3594@1,COG3594@2 NA|NA|NA G Acyltransferase family gnl|extdb|FAM1079-i1-1.1_000328 797515.HMPREF9103_01254 0.0 1615.9 Lactobacillaceae Bacteria 1TRR1@1239,3F49G@33958,4HBW6@91061,COG4485@1,COG4485@2 NA|NA|NA S membrane gnl|extdb|FAM1079-i1-1.1_000329 797515.HMPREF9103_01253 1.9e-113 415.2 Lactobacillaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1U506@1239,3F3M2@33958,4IES2@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues gnl|extdb|FAM1079-i1-1.1_000330 797515.HMPREF9103_01252 4.6e-226 790.4 Lactobacillaceae Bacteria 1VU2I@1239,3F475@33958,4HHZT@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor gnl|extdb|FAM1079-i1-1.1_000331 797515.HMPREF9103_01251 8.2e-128 463.0 Lactobacillaceae Bacteria 1TS81@1239,3F3JF@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal gnl|extdb|FAM1079-i1-1.1_000332 797515.HMPREF9103_01250 5.5e-84 317.0 Lactobacillaceae Z012_06855 ko:K03824 ko00000,ko01000 Bacteria 1V3PW@1239,3F6IT@33958,4HGZK@91061,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) family gnl|extdb|FAM1079-i1-1.1_000333 797515.HMPREF9103_01249 2.7e-227 794.3 Lactobacillaceae aadAT ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 R01939 RC00006 ko00000,ko00001,ko01000 Bacteria 1TPS5@1239,3F4AH@33958,4H9M3@91061,COG1167@1,COG1167@2 NA|NA|NA EK Aminotransferase, class I gnl|extdb|FAM1079-i1-1.1_000335 797515.HMPREF9103_01247 2.1e-255 887.9 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000336 797515.HMPREF9103_01246 2.8e-136 491.1 Lactobacillaceae tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 Bacteria 1TSTW@1239,3F5MN@33958,4HDJ3@91061,COG0819@1,COG0819@2 NA|NA|NA K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway gnl|extdb|FAM1079-i1-1.1_000337 797515.HMPREF9103_01245 3.5e-48 197.6 Lactobacillaceae Bacteria 1U6B5@1239,2C55F@1,30A7Y@2,3F7HV@33958,4IG2P@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000338 797515.HMPREF9103_01244 7.4e-48 196.4 Lactobacillaceae Bacteria 1U6TF@1239,29Z5R@1,30M3H@2,3F8GI@33958,4IGM8@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000339 797515.HMPREF9103_01243 1.1e-164 585.9 Lactobacillaceae fadB4 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 1TPJS@1239,3FC7E@33958,4IQUF@91061,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, NAD binding gnl|extdb|FAM1079-i1-1.1_000341 797515.HMPREF9103_01241 5.3e-57 226.9 Lactobacillaceae yvoA_1 ko:K07979 ko00000,ko03000 Bacteria 1VA2B@1239,3F6GC@33958,4HPK4@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family gnl|extdb|FAM1079-i1-1.1_000342 797515.HMPREF9103_01240 8.7e-125 453.0 Lactobacillaceae skfE ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUP@1239,3FC3H@33958,4HGHM@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_000343 797515.HMPREF9103_01239 3.9e-137 494.2 Lactobacillaceae Bacteria 1U5IX@1239,29NT4@1,309R6@2,3F624@33958,4HZ1H@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000344 797515.HMPREF9103_01238 2.3e-130 471.5 Lactobacillaceae ko:K07052 ko00000 Bacteria 1UPIW@1239,3F6UI@33958,4IFQW@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM1079-i1-1.1_000345 797515.HMPREF9103_01237 1.5e-18 97.8 Lactobacillaceae rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEJ4@1239,3F828@33958,4HNIM@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family gnl|extdb|FAM1079-i1-1.1_000346 797515.HMPREF9103_01236 2.6e-42 177.6 Lactobacillaceae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3F7KX@33958,4HKK1@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site gnl|extdb|FAM1079-i1-1.1_000348 797515.HMPREF9103_01235 1e-57 229.2 Lactobacillaceae Bacteria 1VES3@1239,3F88S@33958,4HNRE@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain gnl|extdb|FAM1079-i1-1.1_000349 797515.HMPREF9103_01234 5.7e-305 1052.7 Lactobacillaceae cdr Bacteria 1TPWW@1239,3FBSF@33958,4HA11@91061,COG0446@1,COG0446@2,COG0607@1,COG0607@2 NA|NA|NA P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM1079-i1-1.1_000350 797515.HMPREF9103_01233 1.5e-36 158.3 Lactobacillaceae yrkD Bacteria 1VFB9@1239,3F74Z@33958,4HNVQ@91061,COG1937@1,COG1937@2 NA|NA|NA S Metal-sensitive transcriptional repressor gnl|extdb|FAM1079-i1-1.1_000351 797515.HMPREF9103_01231 1.4e-167 596.3 Lactobacillaceae Bacteria 1VCF5@1239,3F615@33958,4HQ4B@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family gnl|extdb|FAM1079-i1-1.1_000353 797515.HMPREF9103_00482 3.2e-200 704.1 Lactobacillaceae Bacteria 1U5BI@1239,3F57I@33958,4HE49@91061,COG3568@1,COG3568@2 NA|NA|NA S endonuclease exonuclease phosphatase family protein gnl|extdb|FAM1079-i1-1.1_000354 797515.HMPREF9103_00481 1.1e-80 305.8 Lactobacillaceae yiaC ko:K03826 ko00000,ko01000 Bacteria 1V1GW@1239,3FBC7@33958,4IQ5M@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_000355 797515.HMPREF9103_00480 7.9e-307 1058.9 Lactobacillaceae sfcA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0030145,GO:0036094,GO:0043167,GO:0043169,GO:0043464,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,3F3RH@33958,4HBF1@91061,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme gnl|extdb|FAM1079-i1-1.1_000356 797515.HMPREF9103_00479 4.9e-168 597.0 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family gnl|extdb|FAM1079-i1-1.1_000357 797515.HMPREF9103_00478 1.1e-170 605.9 Lactobacillaceae hoxN ko:K07241 ko00000,ko02000 2.A.52.1 Bacteria 1TSSI@1239,3F4YV@33958,4HEUV@91061,COG2042@1,COG3376@2 NA|NA|NA U High-affinity nickel-transport protein gnl|extdb|FAM1079-i1-1.1_000358 797515.HMPREF9103_00477 5.5e-161 573.5 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family gnl|extdb|FAM1079-i1-1.1_000359 797515.HMPREF9103_00476 4.9e-162 577.0 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1V8DX@1239,3F6IA@33958,4HITY@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family gnl|extdb|FAM1079-i1-1.1_000360 797515.HMPREF9103_00475 0.0 1178.3 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM1079-i1-1.1_000361 797515.HMPREF9103_00473 6.2e-260 902.9 Lactobacillaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHPH@1239,3F3K0@33958,4HA6P@91061,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate gnl|extdb|FAM1079-i1-1.1_000362 797515.HMPREF9103_00472 3.7e-268 930.2 Lactobacillaceae frdC 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F3KJ@33958,4HAXN@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain gnl|extdb|FAM1079-i1-1.1_000363 797515.HMPREF9103_00471 2.8e-243 847.4 Lactobacillaceae Bacteria 1TQ1C@1239,3F3MP@33958,4HDCE@91061,COG3875@1,COG3875@2 NA|NA|NA S Domain of unknown function (DUF2088) gnl|extdb|FAM1079-i1-1.1_000364 797515.HMPREF9103_00470 2.3e-131 474.9 Lactobacillaceae larB ko:K06898 ko00000 Bacteria 1TP0Z@1239,3F526@33958,4HBMK@91061,COG1691@1,COG1691@2 NA|NA|NA S AIR carboxylase gnl|extdb|FAM1079-i1-1.1_000365 797515.HMPREF9103_00469 5.1e-142 510.4 Lactobacillaceae larC 4.99.1.12 ko:K06898,ko:K09121 ko00000,ko01000 Bacteria 1TPAV@1239,3F408@33958,4HC7I@91061,COG1641@1,COG1641@2 NA|NA|NA S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes gnl|extdb|FAM1079-i1-1.1_000366 797515.HMPREF9103_00468 3.4e-57 227.6 Lactobacillaceae larC 4.99.1.12 ko:K06898,ko:K09121 ko00000,ko01000 Bacteria 1V4CM@1239,3F6BC@33958,4IBXK@91061,COG1641@1,COG1641@2 NA|NA|NA S Protein of unknown function DUF111 gnl|extdb|FAM1079-i1-1.1_000367 797515.HMPREF9103_00467 1.8e-153 548.5 Lactobacillaceae larE ko:K06864 ko00000 Bacteria 1TPB2@1239,3F3Z9@33958,4HAZT@91061,COG1606@1,COG1606@2 NA|NA|NA S NAD synthase gnl|extdb|FAM1079-i1-1.1_000368 797515.HMPREF9103_00466 1.7e-71 275.4 Lactobacillaceae Bacteria 1VCK0@1239,3F6FQ@33958,4I1W9@91061,COG0716@1,COG0716@2 NA|NA|NA C FMN binding gnl|extdb|FAM1079-i1-1.1_000369 797515.HMPREF9103_00465 6.9e-92 343.2 Lactobacillaceae 1.8.5.2 ko:K15977,ko:K16937 ko00920,ko01120,map00920,map01120 R07177 ko00000,ko00001,ko01000 3.D.4.9 Bacteria 1V4ER@1239,3F6YV@33958,4HGZN@91061,COG2259@1,COG2259@2 NA|NA|NA S DoxX gnl|extdb|FAM1079-i1-1.1_000370 797515.HMPREF9103_00464 1.3e-173 615.5 Lactobacillaceae ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TPV8@1239,3F55H@33958,4H9SI@91061,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000371 797515.HMPREF9103_00463 4.2e-278 963.4 Lactobacillaceae proWX ko:K05845,ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TQ7D@1239,3F44S@33958,4HBDR@91061,COG1174@1,COG1174@2,COG1732@1,COG1732@2 NA|NA|NA EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) gnl|extdb|FAM1079-i1-1.1_000372 797515.HMPREF9103_00462 1.2e-174 619.0 Lactobacillaceae Bacteria 1TPGA@1239,3F4HK@33958,4HER3@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase gnl|extdb|FAM1079-i1-1.1_000373 797515.HMPREF9103_00461 1.3e-31 141.7 Lactobacillaceae Bacteria 1U88C@1239,2BRNC@1,32KMY@2,3FAP4@33958,4II64@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000374 797515.HMPREF9103_00460 6.9e-256 889.4 Lactobacillaceae npr 1.11.1.1 ko:K05910 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase gnl|extdb|FAM1079-i1-1.1_000375 797515.HMPREF9103_00459 2e-129 468.4 Lactobacillaceae Bacteria 1UZ0H@1239,3FC63@33958,4HGGU@91061,COG0789@1,COG0789@2 NA|NA|NA K transcriptional regulator, MerR family gnl|extdb|FAM1079-i1-1.1_000376 797515.HMPREF9103_00458 1.2e-97 362.5 Bacilli immR_1 Bacteria 1V8SA@1239,4HJMH@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_000377 525318.HMPREF0497_0161 5.8e-175 620.2 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F5YI@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gnl|extdb|FAM1079-i1-1.1_000378 797515.HMPREF9103_00454 4e-214 750.7 Lactobacillaceae ydiC1 Bacteria 1TPRN@1239,3F5YC@33958,4HBXJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator gnl|extdb|FAM1079-i1-1.1_000379 797515.HMPREF9103_00305 2e-174 618.6 Lactobacillaceae yeaN GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 1TP9R@1239,3F5BH@33958,4H9YZ@91061,COG2807@1,COG2807@2 NA|NA|NA P Major Facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000380 797515.HMPREF9103_00306 5.8e-118 430.3 Lactobacillaceae pdhR Bacteria 1UVTZ@1239,3F98V@33958,4I39F@91061,COG2186@1,COG2186@2 NA|NA|NA K Transcriptional regulator, GntR family gnl|extdb|FAM1079-i1-1.1_000381 797515.HMPREF9103_00307 8.6e-93 346.3 Lactobacillaceae yvqK GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 ko:K00798,ko:K13821 ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130 M00122 R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268 RC00080,RC00083,RC00216,RC00242,RC00255,RC00533 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1UZ2W@1239,3F6MY@33958,4HF48@91061,COG2096@1,COG2096@2 NA|NA|NA S cob(I)alamin adenosyltransferase gnl|extdb|FAM1079-i1-1.1_000382 797515.HMPREF9103_00308 3.8e-44 183.7 Lactobacillaceae Bacteria 1U7WV@1239,29QDA@1,30BCJ@2,3FA9T@33958,4IHU7@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000383 797515.HMPREF9103_00309 0.0 1534.2 Lactobacillaceae rtpR 1.1.98.6,1.17.4.1,1.17.4.2 ko:K00525,ko:K00527,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02017,R02018,R02019,R02020,R02022,R02023,R02024,R04315,R11633,R11634,R11635,R11636 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TT3U@1239,3F3VU@33958,4HFF1@91061,COG0209@1,COG0209@2 NA|NA|NA F ribonucleoside-triphosphate reductase activity gnl|extdb|FAM1079-i1-1.1_000384 525318.HMPREF0497_0151 1.3e-186 659.1 Lactobacillaceae patB 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I gnl|extdb|FAM1079-i1-1.1_000385 797515.HMPREF9103_00313 1.6e-101 375.9 Lactobacillaceae Bacteria 1TQXN@1239,3F4Y5@33958,4HBHT@91061,COG5434@1,COG5434@2 NA|NA|NA M Protein of unknown function (DUF3737) gnl|extdb|FAM1079-i1-1.1_000386 797515.HMPREF9103_00314 5.1e-185 653.7 Lactobacillaceae ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1UY33@1239,3F41X@33958,4HDN5@91061,COG0659@1,COG0659@2 NA|NA|NA P secondary active sulfate transmembrane transporter activity gnl|extdb|FAM1079-i1-1.1_000387 797515.HMPREF9103_00315 1.6e-94 352.1 Lactobacillaceae apt 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 1V9BZ@1239,3FBI8@33958,4IQPM@91061,COG0503@1,COG0503@2 NA|NA|NA F Phosphoribosyl transferase domain gnl|extdb|FAM1079-i1-1.1_000388 797515.HMPREF9103_00316 6.5e-66 256.5 Lactobacillaceae Bacteria 1U7S9@1239,29QAC@1,30B9H@2,3FA3R@33958,4IHPM@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000389 797515.HMPREF9103_00318 6.7e-256 889.4 Lactobacillaceae ntaA Bacteria 1TQZ0@1239,3F9P0@33958,4HAF9@91061,COG2141@1,COG2141@2 NA|NA|NA C FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family gnl|extdb|FAM1079-i1-1.1_000393 797515.HMPREF9103_02496 3.7e-160 570.9 Lactobacillaceae mleP3 ko:K07088 ko00000 Bacteria 1V0E3@1239,3F4BN@33958,4IQTM@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein gnl|extdb|FAM1079-i1-1.1_000395 797515.HMPREF9103_02498 2.1e-227 794.7 Lactobacillaceae icaA ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 Bacteria 1TR2P@1239,3F3RY@33958,4HAQN@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase gnl|extdb|FAM1079-i1-1.1_000396 797515.HMPREF9103_02499 8.5e-45 186.0 Lactobacillaceae Bacteria 1U6TK@1239,2C2ES@1,3027K@2,3F8GW@33958,4IGMF@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000397 797515.HMPREF9103_02500 4.3e-174 617.1 Lactobacillaceae icaB GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K21478 R03096 RC00010 ko00000,ko01000 Bacteria 1V47P@1239,3F5B9@33958,4HHJX@91061,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase gnl|extdb|FAM1079-i1-1.1_000398 797515.HMPREF9103_02501 4.7e-128 463.8 Lactobacillaceae hchA Bacteria 1UG8E@1239,3FB74@33958,4HCV7@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family gnl|extdb|FAM1079-i1-1.1_000399 797515.HMPREF9103_02502 1.4e-53 215.3 Lactobacillaceae ko:K03892 ko00000,ko03000 Bacteria 1V6Z2@1239,3F7CV@33958,4HKFB@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional gnl|extdb|FAM1079-i1-1.1_000400 797515.HMPREF9103_02503 1.4e-181 642.1 Lactobacillaceae GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0007275,GO:0007399,GO:0008150,GO:0009987,GO:0010975,GO:0016020,GO:0019867,GO:0022008,GO:0030154,GO:0031090,GO:0031344,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045664,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051239,GO:0051960,GO:0060284,GO:0065007,GO:0098588,GO:0098805,GO:0120035,GO:2000026 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F4EJ@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase gnl|extdb|FAM1079-i1-1.1_000401 797515.HMPREF9103_02504 2e-238 831.2 Lactobacillaceae Bacteria 1UGRE@1239,2BGV4@1,32AUU@2,3F5YY@33958,4IF8F@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000402 525318.HMPREF0497_0129 3.3e-20 103.6 Lactobacillaceae Bacteria 1U7YZ@1239,2AKX0@1,31BQH@2,3FACB@33958,4IHWD@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000403 797515.HMPREF9103_02506 5.9e-167 594.3 Lactobacillaceae Bacteria 1V83S@1239,3F5ER@33958,4HY51@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO gnl|extdb|FAM1079-i1-1.1_000406 797515.HMPREF9103_02509 1.1e-217 762.3 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent gnl|extdb|FAM1079-i1-1.1_000407 1423743.JCM14108_1166 2.5e-73 282.0 Lactobacillaceae yoaK Bacteria 1U5PX@1239,3F6AC@33958,4IFE7@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) gnl|extdb|FAM1079-i1-1.1_000408 797515.HMPREF9103_02513 2.2e-146 525.0 Lactobacillaceae pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TRCR@1239,3F3V7@33958,4HHME@91061,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase gnl|extdb|FAM1079-i1-1.1_000409 797515.HMPREF9103_02514 2.1e-108 398.3 Lactobacillaceae ywlG Bacteria 1V3H0@1239,3F66D@33958,4HH6F@91061,COG4475@1,COG4475@2 NA|NA|NA S Belongs to the UPF0340 family gnl|extdb|FAM1079-i1-1.1_000410 797515.HMPREF9103_02515 3.1e-84 317.8 Lactobacillaceae hmpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1VBBN@1239,3F6W6@33958,4HNM0@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component gnl|extdb|FAM1079-i1-1.1_000411 797515.HMPREF9103_02517 2.1e-93 348.6 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VZE5@1239,3F73V@33958,4HYX4@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX amino terminal protease gnl|extdb|FAM1079-i1-1.1_000412 797515.HMPREF9103_02519 9.8e-255 885.6 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F3QA@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase gnl|extdb|FAM1079-i1-1.1_000413 797515.HMPREF9103_02520 4.3e-95 354.0 Lactobacillaceae Bacteria 1U5P9@1239,2AM9B@1,31C46@2,3F69D@33958,4IFDS@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000414 797515.HMPREF9103_02521 5.5e-175 620.2 Lactobacillaceae malR ko:K02529 ko00000,ko03000 Bacteria 1VSUF@1239,3FC5H@33958,4HUWB@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain gnl|extdb|FAM1079-i1-1.1_000415 797515.HMPREF9103_02522 8.5e-249 865.9 Lactobacillaceae ydiC1 Bacteria 1TPRN@1239,3F4D4@33958,4HBXJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000416 797515.HMPREF9103_02523 7.9e-117 426.4 Bacteria 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria COG3764@1,COG3764@2 NA|NA|NA M Sortase family gnl|extdb|FAM1079-i1-1.1_000417 797515.HMPREF9103_02524 4.5e-109 400.6 Lactobacillaceae Bacteria 1W3AZ@1239,28UQM@1,2ZGUY@2,3F65Q@33958,4I0YM@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000418 797515.HMPREF9103_02525 0.0 1179.1 Bacteria ko:K01421 ko00000 Bacteria COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation gnl|extdb|FAM1079-i1-1.1_000419 797515.HMPREF9103_02526 9.6e-302 1042.0 Lactobacillaceae tagE3 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1TR6K@1239,3FBGJ@33958,4IQBA@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein gnl|extdb|FAM1079-i1-1.1_000420 797515.HMPREF9103_02527 1.6e-293 1014.6 Lactobacillaceae 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1VSNK@1239,3F4VP@33958,4HU8G@91061,COG0438@1,COG0438@2 NA|NA|NA M Poly(Glycerol-phosphate) alpha-glucosyltransferase gnl|extdb|FAM1079-i1-1.1_000421 797515.HMPREF9103_02529 0.0 1096.3 Lactobacillaceae prgA Bacteria 1U5DQ@1239,3F5NM@33958,4IF55@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation gnl|extdb|FAM1079-i1-1.1_000426 797515.HMPREF9103_01842 2.9e-114 417.9 Lactobacillaceae Bacteria 1U5PP@1239,29NVY@1,309U2@2,3F6A0@33958,4IFE3@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000427 1423743.JCM14108_412 1.7e-203 715.3 Lactobacillaceae ko:K03458 ko00000 2.A.40 Bacteria 1TNZZ@1239,3FC8X@33958,4HCX6@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease gnl|extdb|FAM1079-i1-1.1_000430 1423743.JCM14108_415 1.4e-112 412.5 Lactobacillaceae Bacteria 1UU2F@1239,3F9TV@33958,4HCVI@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain gnl|extdb|FAM1079-i1-1.1_000432 1158601.I585_01349 3.1e-51 210.7 Enterococcaceae Bacteria 1UE4Y@1239,4B48T@81852,4HRCE@91061,COG0846@1,COG0846@2 NA|NA|NA K SIR2-like domain gnl|extdb|FAM1079-i1-1.1_000433 1423780.LOT_1606 2.2e-48 198.0 Lactobacillaceae Bacteria 1VA3E@1239,3F7T0@33958,4HKDQ@91061,COG1694@1,COG1694@2 NA|NA|NA S MazG-like family gnl|extdb|FAM1079-i1-1.1_000435 1423734.JCM14202_2170 1.2e-12 79.7 Lactobacillaceae Bacteria 1VN33@1239,3F7RZ@33958,4HSF4@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM1079-i1-1.1_000436 1423734.JCM14202_2171 1.1e-83 316.6 Bacilli dltE ko:K14189 ko00000,ko01000 Bacteria 1TT89@1239,4HC2F@91061,COG3967@1,COG3967@2 NA|NA|NA M Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM1079-i1-1.1_000437 1423734.JCM14202_2172 2.3e-100 372.1 Lactobacillaceae Bacteria 1TX7J@1239,3F63Y@33958,4I641@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family gnl|extdb|FAM1079-i1-1.1_000439 1138822.PL11_00750 1.3e-10 74.3 Lactobacillaceae Bacteria 1U8AZ@1239,29PJJ@1,30BM0@2,3FASE@33958,4II8Z@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000352 797515.HMPREF9103_01230 5.3e-209 733.4 Lactobacillaceae Bacteria 1VX75@1239,3F5WJ@33958,4HH0B@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family group 2 gnl|extdb|FAM1079-i1-1.1_000390 797515.HMPREF9103_00319 4.9e-162 577.0 Lactobacillaceae Bacteria 1U5DH@1239,2DKJ3@1,309NE@2,3F5MT@33958,4IF4V@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000391 797515.HMPREF9103_02494 7.6e-126 456.4 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1UYDN@1239,3F469@33958,4HJE5@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter gnl|extdb|FAM1079-i1-1.1_000394 797515.HMPREF9103_02497 5.2e-209 733.4 Lactobacillaceae strH 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 1VDY0@1239,3F5FB@33958,4HKGG@91061,COG3525@1,COG3525@2 NA|NA|NA G Glycosyl hydrolase family 20, catalytic domain gnl|extdb|FAM1079-i1-1.1_000404 797515.HMPREF9103_02507 0.0 1081.2 Lactobacillaceae Bacteria 1V693@1239,3F3US@33958,4ISGZ@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family gnl|extdb|FAM1079-i1-1.1_000428 1423743.JCM14108_413 8.8e-164 583.2 Bacilli luxE 6.2.1.19 ko:K06046 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Bacteria 1UYJ0@1239,4HD80@91061,COG1541@1,COG1541@2 NA|NA|NA H Acyl-protein synthetase, LuxE gnl|extdb|FAM1079-i1-1.1_000429 1423743.JCM14108_414 1e-196 693.0 Bacilli luxC 1.2.1.50 ko:K03400 ko02020,ko02024,map02020,map02024 R10549 RC00004,RC00184 ko00000,ko00001,ko01000 Bacteria 1TSYP@1239,4HE2I@91061,COG1012@1,COG1012@2 NA|NA|NA C Acyl-CoA reductase (LuxC) gnl|extdb|FAM1079-i1-1.1_000431 1423734.JCM14202_144 6.1e-13 80.1 Lactobacillaceae hoxN ko:K07241 ko00000,ko02000 2.A.52.1 Bacteria 1TSSI@1239,3F4YV@33958,4HEUV@91061,COG2042@1,COG3376@2 NA|NA|NA U High-affinity nickel-transport protein gnl|extdb|FAM1079-i1-1.1_000440 797515.HMPREF9103_01185 7.2e-121 439.9 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3F4ST@33958,4HF3K@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase gnl|extdb|FAM1079-i1-1.1_000441 797515.HMPREF9103_01186 0.0 1824.7 Lactobacillaceae trePP GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.216,2.4.1.8,3.1.3.12,3.2.1.28 ko:K00691,ko:K01087,ko:K01194,ko:K03731 ko00500,ko01100,map00500,map01100 R00010,R01555,R02778 RC00017,RC00049 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1TQMB@1239,3F4TB@33958,4HD7Z@91061,COG1554@1,COG1554@2 NA|NA|NA G Glycosyl hydrolase family 65 central catalytic domain gnl|extdb|FAM1079-i1-1.1_000442 1423743.JCM14108_192 4e-49 200.7 Lactobacillaceae mscL GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1VA14@1239,3F6YZ@33958,4HKIA@91061,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell gnl|extdb|FAM1079-i1-1.1_000443 797515.HMPREF9103_01189 7.1e-29 132.9 Lactobacillaceae Bacteria 1U6TY@1239,29PNH@1,30AKQ@2,3F8HD@33958,4IGMS@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000444 797515.HMPREF9103_01190 0.0 1207.2 Lactobacillaceae Bacteria 1V06T@1239,3F47I@33958,4HFKG@91061,COG4934@1,COG4934@2 NA|NA|NA O Pro-kumamolisin, activation domain gnl|extdb|FAM1079-i1-1.1_000445 525318.HMPREF0497_2708 7.1e-79 300.4 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VFRX@1239,3FC4Z@33958,4HPZB@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM1079-i1-1.1_000446 797515.HMPREF9103_01192 3.4e-200 704.1 Lactobacillaceae dmpA 3.4.11.19 ko:K01266 ko00000,ko01000,ko01002 Bacteria 1TQHA@1239,3F53N@33958,4HAZM@91061,COG3191@1,COG3191@2 NA|NA|NA EQ Peptidase family S58 gnl|extdb|FAM1079-i1-1.1_000447 797515.HMPREF9103_01193 1.2e-105 389.0 Lactobacillaceae Bacteria 1VE2G@1239,3F6FB@33958,4HMDI@91061,COG4990@1,COG4990@2 NA|NA|NA M Peptidase_C39 like family gnl|extdb|FAM1079-i1-1.1_000448 797515.HMPREF9103_01194 1.7e-301 1041.2 Lactobacillaceae ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein gnl|extdb|FAM1079-i1-1.1_000449 797515.HMPREF9103_01195 1.5e-189 668.7 Lactobacillaceae ykfB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 R10938 RC03309 ko00000,ko01000 Bacteria 1TQMS@1239,3F4XQ@33958,4HCY5@91061,COG4948@1,COG4948@2 NA|NA|NA M Belongs to the mandelate racemase muconate lactonizing enzyme family gnl|extdb|FAM1079-i1-1.1_000450 525318.HMPREF0497_2701 5.9e-139 500.4 Lactobacillaceae ykfC 3.4.14.13 ko:K20742,ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1TSZ0@1239,3F5GI@33958,4HBUM@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family gnl|extdb|FAM1079-i1-1.1_000451 797515.HMPREF9103_01198 3.1e-133 481.1 Lactobacillaceae 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VAJP@1239,3FC20@33958,4HK3F@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family gnl|extdb|FAM1079-i1-1.1_000452 797515.HMPREF9103_02397 1.3e-75 288.9 Lactobacillaceae usp Bacteria 1V3NY@1239,3F694@33958,4IFDK@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein gnl|extdb|FAM1079-i1-1.1_000454 797515.HMPREF9103_00109 2.8e-120 438.0 Lactobacillaceae Bacteria 1UJ9U@1239,2DSFV@1,33FZI@2,3FBW5@33958,4ITK0@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000455 797515.HMPREF9103_00108 1.8e-54 218.8 Lactobacillaceae ohrR Bacteria 1V6G0@1239,3FC7H@33958,4HI3T@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000456 797515.HMPREF9103_00107 7.3e-39 166.0 Lactobacillaceae Bacteria 1W6D0@1239,2930D@1,2ZQHQ@2,3F7KZ@33958,4HZS5@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000457 797515.HMPREF9103_00106 0.0 1288.5 Lactobacillaceae asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRPB@1239,3F3NT@33958,4HAIP@91061,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase gnl|extdb|FAM1079-i1-1.1_000458 797515.HMPREF9103_00105 1.3e-295 1021.5 Lactobacillaceae murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,3F3UE@33958,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan gnl|extdb|FAM1079-i1-1.1_000459 797515.HMPREF9103_00104 4e-250 870.2 Lactobacillaceae yxbA 6.3.1.12 ko:K17810 ko00000,ko01000 Bacteria 1TQPN@1239,3F3S7@33958,4HAB0@91061,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp enzyme gnl|extdb|FAM1079-i1-1.1_000460 797515.HMPREF9103_00103 1.1e-135 489.2 Lactobacillaceae racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1V34N@1239,3F3XZ@33958,4HG8W@91061,COG1794@1,COG1794@2 NA|NA|NA G Belongs to the aspartate glutamate racemases family gnl|extdb|FAM1079-i1-1.1_000463 797515.HMPREF9103_00100 0.0 1111.7 Lactobacillaceae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPEZ@1239,3F4DE@33958,4HAR3@91061,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase gnl|extdb|FAM1079-i1-1.1_000464 525318.HMPREF0497_2685 0.0 1270.8 Lactobacillaceae pbp2A 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F49Q@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein gnl|extdb|FAM1079-i1-1.1_000465 797515.HMPREF9103_00097 2.5e-29 134.8 Lactobacillaceae yheA Bacteria 1VASS@1239,3F822@33958,4HKKC@91061,COG3679@1,COG3679@2 NA|NA|NA S Belongs to the UPF0342 family gnl|extdb|FAM1079-i1-1.1_000466 797515.HMPREF9103_00096 1.7e-232 811.6 Lactobacillaceae yhaO ko:K03547 ko00000,ko03400 Bacteria 1TWMI@1239,3F3PX@33958,4HCA0@91061,COG0420@1,COG0420@2 NA|NA|NA L Ser Thr phosphatase family protein gnl|extdb|FAM1079-i1-1.1_000467 797515.HMPREF9103_00095 0.0 1561.2 Lactobacillaceae Bacteria 1TQP3@1239,3F3PF@33958,4HBCA@91061,COG4717@1,COG4717@2 NA|NA|NA L AAA domain gnl|extdb|FAM1079-i1-1.1_000468 797515.HMPREF9103_00094 5.3e-178 630.2 Lactobacillaceae ko:K03698 ko00000,ko01000,ko03019 Bacteria 1TPIU@1239,3F4SF@33958,4HB1M@91061,COG3481@1,COG3481@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. gnl|extdb|FAM1079-i1-1.1_000469 797515.HMPREF9103_00091 2.3e-151 541.6 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1TX3R@1239,3F45W@33958,4HC85@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins gnl|extdb|FAM1079-i1-1.1_000470 797515.HMPREF9103_00090 7.1e-23 113.2 Lactobacillaceae Bacteria 1U6P6@1239,29PJB@1,30AHG@2,3F88K@33958,4IGG6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000471 797515.HMPREF9103_00089 2e-76 291.6 Lactobacillaceae hit ko:K02503 ko00000,ko04147 Bacteria 1V9ZJ@1239,3F6K5@33958,4HIG2@91061,COG0537@1,COG0537@2 NA|NA|NA FG histidine triad gnl|extdb|FAM1079-i1-1.1_000472 797515.HMPREF9103_00088 2.1e-126 458.4 Lactobacillaceae ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3F444@33958,4HA2B@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000473 797515.HMPREF9103_00087 5.9e-206 723.4 Lactobacillaceae ecsB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1VG@1239,3F4HH@33958,4HG1K@91061,COG4473@1,COG4473@2 NA|NA|NA U ABC transporter gnl|extdb|FAM1079-i1-1.1_000474 797515.HMPREF9103_00086 1.2e-122 445.7 Lactobacillaceae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1TQCA@1239,3F3QM@33958,4HC08@91061,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA gnl|extdb|FAM1079-i1-1.1_000475 797515.HMPREF9103_00085 3.6e-51 207.2 Lactobacillaceae Bacteria 1U72H@1239,29PUU@1,30AT1@2,3F8W5@33958,4IGWZ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000476 797515.HMPREF9103_00084 3.9e-56 223.8 Lactobacillaceae ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1VAS6@1239,3F72K@33958,4HKGM@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin gnl|extdb|FAM1079-i1-1.1_000477 797515.HMPREF9103_00083 7.8e-117 426.4 Lactobacillaceae pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V3R1@1239,3F58U@33958,4HHBI@91061,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily gnl|extdb|FAM1079-i1-1.1_000478 797515.HMPREF9103_00082 0.0 1517.7 Lactobacillaceae sftA ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F441@33958,4HA1S@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family gnl|extdb|FAM1079-i1-1.1_000479 797515.HMPREF9103_00081 8e-257 892.5 Lactobacillaceae mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 1TQ5H@1239,3F49J@33958,4HAR4@91061,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family gnl|extdb|FAM1079-i1-1.1_000480 797515.HMPREF9103_00080 8.6e-117 426.4 Lactobacillaceae ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V779@1239,3F3QH@33958,4HIX1@91061,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family gnl|extdb|FAM1079-i1-1.1_000481 797515.HMPREF9103_00079 0.0 1722.2 Lactobacillaceae polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPKJ@1239,3F3ZA@33958,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity gnl|extdb|FAM1079-i1-1.1_000482 797515.HMPREF9103_00078 2.2e-159 568.2 Lactobacillaceae fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPM9@1239,3F43E@33958,4H9Q7@91061,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates gnl|extdb|FAM1079-i1-1.1_000483 797515.HMPREF9103_00077 3.5e-103 380.9 Lactobacillaceae coaE 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6FS@1239,3F6WF@33958,4HII3@91061,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A gnl|extdb|FAM1079-i1-1.1_000484 797515.HMPREF9103_00076 1.6e-85 322.0 Lactobacillaceae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,3F65S@33958,4HGXA@91061,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes gnl|extdb|FAM1079-i1-1.1_000485 797515.HMPREF9103_00075 4.6e-258 896.7 Lactobacillaceae dnaB ko:K03346 ko00000,ko03032 Bacteria 1TSBB@1239,3F5D7@33958,4H9RI@91061,COG3611@1,COG3611@2 NA|NA|NA L replication initiation and membrane attachment gnl|extdb|FAM1079-i1-1.1_000486 797515.HMPREF9103_00074 3e-173 614.4 Lactobacillaceae dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K11144 ko00000,ko03032 Bacteria 1TPZX@1239,3F4JK@33958,4HABS@91061,COG1484@1,COG1484@2 NA|NA|NA L Primosomal protein DnaI gnl|extdb|FAM1079-i1-1.1_000487 797515.HMPREF9103_00073 0.0 1295.0 Lactobacillaceae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP78@1239,3F3TC@33958,4HABZ@91061,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) gnl|extdb|FAM1079-i1-1.1_000488 797515.HMPREF9103_00072 1.3e-85 322.4 Lactobacillaceae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1V1RC@1239,3F4MS@33958,4HFUS@91061,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins gnl|extdb|FAM1079-i1-1.1_000489 797515.HMPREF9103_00071 2.9e-27 127.1 Lactobacillaceae rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VF5W@1239,3F7CQ@33958,4HNIQ@91061,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family gnl|extdb|FAM1079-i1-1.1_000490 797515.HMPREF9103_00070 2.3e-57 228.0 Lactobacillaceae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DB@1239,3F6HZ@33958,4HH2W@91061,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit gnl|extdb|FAM1079-i1-1.1_000491 797515.HMPREF9103_00069 4.4e-94 350.5 Lactobacillaceae yqeG ko:K07015 ko00000 Bacteria 1V6KM@1239,3F46V@33958,4HGAV@91061,COG2179@1,COG2179@2 NA|NA|NA S HAD phosphatase, family IIIA gnl|extdb|FAM1079-i1-1.1_000492 797515.HMPREF9103_00068 1e-215 755.7 Lactobacillaceae yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 ko:K06948 ko00000,ko03009 Bacteria 1TPM2@1239,3F4JU@33958,4HAAF@91061,COG1161@1,COG1161@2 NA|NA|NA S Ribosome biogenesis GTPase YqeH gnl|extdb|FAM1079-i1-1.1_000493 797515.HMPREF9103_00067 1.9e-47 194.9 Lactobacillaceae yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 1VEGM@1239,3F7EW@33958,4HKC7@91061,COG1534@1,COG1534@2 NA|NA|NA J RNA-binding protein gnl|extdb|FAM1079-i1-1.1_000494 797515.HMPREF9103_00066 2e-117 428.3 Lactobacillaceae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3SK@1239,3F4D6@33958,4HGXK@91061,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) gnl|extdb|FAM1079-i1-1.1_000495 797515.HMPREF9103_00065 6.5e-113 413.3 Lactobacillaceae nadD 2.7.6.3,2.7.7.18 ko:K00950,ko:K00969,ko:K06950 ko00760,ko00790,ko01100,map00760,map00790,map01100 M00115,M00126,M00841 R00137,R03005,R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6Y1@1239,3F47C@33958,4HHRY@91061,COG1713@1,COG1713@2 NA|NA|NA H Hydrolase, HD family gnl|extdb|FAM1079-i1-1.1_000496 1423743.JCM14108_923 8.1e-55 219.5 Lactobacillaceae rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 1VA2Z@1239,3F7QN@33958,4HKEJ@91061,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation gnl|extdb|FAM1079-i1-1.1_000497 797515.HMPREF9103_00062 2.8e-142 511.1 Lactobacillaceae yqeM Bacteria 1TQUF@1239,3F4KM@33958,4HD2W@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase gnl|extdb|FAM1079-i1-1.1_000498 797515.HMPREF9103_00061 6.5e-215 753.1 Lactobacillaceae ylbM Bacteria 1TPP2@1239,3F3QC@33958,4HAZJ@91061,COG1323@1,COG1323@2 NA|NA|NA S Belongs to the UPF0348 family gnl|extdb|FAM1079-i1-1.1_000499 797515.HMPREF9103_00060 1.3e-99 369.0 Lactobacillaceae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1VB08@1239,3F61Z@33958,4HME9@91061,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 gnl|extdb|FAM1079-i1-1.1_000500 525318.HMPREF0497_2648 5.1e-23 112.8 Bacteria rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family gnl|extdb|FAM1079-i1-1.1_000501 797515.HMPREF9103_01813 7.4e-194 682.9 Lactobacillaceae adhP GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0006081,GO:0006117,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0045471,GO:0046185,GO:0046187,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0097305,GO:1901575,GO:1901700 1.1.1.1 ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 iECP_1309.ECP_1480 Bacteria 1TP5B@1239,3F4PR@33958,4HA9Z@91061,COG1064@1,COG1064@2 NA|NA|NA C alcohol dehydrogenase gnl|extdb|FAM1079-i1-1.1_000502 525318.HMPREF0497_2646 3.6e-120 437.6 Lactobacillaceae Bacteria 1TS81@1239,3F421@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator gnl|extdb|FAM1079-i1-1.1_000503 797515.HMPREF9103_01816 1e-263 915.6 Lactobacillaceae arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPSK@1239,3F3NU@33958,4HAH5@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM1079-i1-1.1_000504 797515.HMPREF9103_01817 3.1e-171 607.8 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TSDN@1239,3F3P3@33958,4HCC8@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins gnl|extdb|FAM1079-i1-1.1_000506 797515.HMPREF9103_00893 4.9e-142 510.4 Lactobacillaceae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1V3JP@1239,3F3NF@33958,4HCF5@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gnl|extdb|FAM1079-i1-1.1_000507 797515.HMPREF9103_00894 5.3e-89 333.6 Lactobacillaceae 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974,ko:K06885,ko:K06950 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1UHY1@1239,3FBRW@33958,4ISAF@91061,COG1078@1,COG1078@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. gnl|extdb|FAM1079-i1-1.1_000508 797515.HMPREF9103_00895 1.9e-61 241.5 Lactobacillaceae yodB Bacteria 1VBI7@1239,3F7FK@33958,4HKBR@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family gnl|extdb|FAM1079-i1-1.1_000509 797515.HMPREF9103_00896 2.4e-203 714.5 Lactobacillaceae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPFW@1239,3F4NT@33958,4HAVN@91061,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily gnl|extdb|FAM1079-i1-1.1_000510 797515.HMPREF9103_00897 0.0 1594.7 Lactobacillaceae pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1TP98@1239,3F3V3@33958,4HAQ9@91061,COG0072@1,COG0072@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily gnl|extdb|FAM1079-i1-1.1_000511 797515.HMPREF9103_00898 3e-204 717.6 Lactobacillaceae mltG ko:K07082 ko00000 Bacteria 1TS48@1239,3F4IG@33958,4HAUV@91061,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation gnl|extdb|FAM1079-i1-1.1_000512 797515.HMPREF9103_00899 3.2e-121 441.0 Lactobacillaceae udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,3F3KE@33958,4HAVR@91061,COG0572@1,COG0572@2 NA|NA|NA F Cytidine monophosphokinase gnl|extdb|FAM1079-i1-1.1_000513 797515.HMPREF9103_00900 1.3e-79 302.4 Lactobacillaceae greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03624 ko00000,ko03021 Bacteria 1V44S@1239,3F4ZF@33958,4HGZU@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides gnl|extdb|FAM1079-i1-1.1_000514 797515.HMPREF9103_00901 8.3e-56 222.6 Lactobacillaceae yneR Bacteria 1VEQE@1239,3F7SB@33958,4HNU2@91061,COG4841@1,COG4841@2 NA|NA|NA S Belongs to the HesB IscA family gnl|extdb|FAM1079-i1-1.1_000515 525318.HMPREF0497_2633 0.0 1279.2 Lactobacillaceae Bacteria 1TRR1@1239,3FC7P@33958,4HCR9@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO gnl|extdb|FAM1079-i1-1.1_000516 797515.HMPREF9103_00905 0.0 1146.0 Lactobacillaceae pbp2b 3.4.16.4 ko:K00687,ko:K05515,ko:K12553,ko:K21465 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQHY@1239,3F3KH@33958,4HAFX@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein gnl|extdb|FAM1079-i1-1.1_000517 525318.HMPREF0497_2631 2.7e-20 103.6 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEJ4@1239,3F828@33958,4HNIM@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family gnl|extdb|FAM1079-i1-1.1_000518 797515.HMPREF9103_00906 5.3e-98 363.6 Lactobacillaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,3F4KQ@33958,4HM35@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family gnl|extdb|FAM1079-i1-1.1_000519 797515.HMPREF9103_00907 5.8e-107 393.7 Lactobacillaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,3F3WR@33958,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Peptidase, S54 family gnl|extdb|FAM1079-i1-1.1_000520 797515.HMPREF9103_00908 5.8e-35 152.9 Lactobacillaceae yqgQ Bacteria 1VK83@1239,3F83I@33958,4HRG2@91061,COG4483@1,COG4483@2 NA|NA|NA S Bacterial protein of unknown function (DUF910) gnl|extdb|FAM1079-i1-1.1_000521 797515.HMPREF9103_00909 2.3e-187 661.4 Lactobacillaceae glk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS07790 Bacteria 1TPKW@1239,3F4F0@33958,4HBAU@91061,COG1940@1,COG1940@2 NA|NA|NA G Glucokinase gnl|extdb|FAM1079-i1-1.1_000522 797515.HMPREF9103_00910 7.8e-73 279.6 Lactobacillaceae yqhL Bacteria 1VAI7@1239,3F67E@33958,4HKCE@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like protein gnl|extdb|FAM1079-i1-1.1_000523 797515.HMPREF9103_00911 2.3e-23 114.0 Lactobacillaceae WQ51_02665 Bacteria 1VPEZ@1239,2C91M@1,33E1E@2,3F8C0@33958,4HRR2@91061 NA|NA|NA S Protein of unknown function (DUF3042) gnl|extdb|FAM1079-i1-1.1_000524 525318.HMPREF0497_2624 7.7e-124 449.9 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4CS@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C phosphodiesterase gnl|extdb|FAM1079-i1-1.1_000525 797515.HMPREF9103_00913 2.1e-171 608.2 Lactobacillaceae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1TPSC@1239,3F3XS@33958,4HAVW@91061,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) gnl|extdb|FAM1079-i1-1.1_000526 797515.HMPREF9103_00914 3.2e-68 264.2 Lactobacillaceae glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V6JE@1239,3F7RX@33958,4HKM6@91061,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000527 797515.HMPREF9103_00915 1.4e-264 918.3 Lactobacillaceae glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1TNZA@1239,3F41A@33958,4HACE@91061,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase gnl|extdb|FAM1079-i1-1.1_000528 797515.HMPREF9103_00916 6e-160 570.1 Lactobacillaceae Bacteria 1V8SY@1239,2AZ1J@1,31R7P@2,3F4MX@33958,4HJRD@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000529 797515.HMPREF9103_00917 9.2e-175 619.4 Lactobacillaceae Bacteria 1VK1W@1239,2F367@1,33W0S@2,3F3MT@33958,4HWH4@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000530 797515.HMPREF9103_00918 9.9e-97 359.4 Lactobacillaceae dut Bacteria 1VGAY@1239,3F6E4@33958,4HPDT@91061,COG4508@1,COG4508@2 NA|NA|NA S Protein conserved in bacteria gnl|extdb|FAM1079-i1-1.1_000533 797515.HMPREF9103_02536 2e-49 201.4 Lactobacillaceae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YH@1239,3F6WT@33958,4HIGK@91061,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 gnl|extdb|FAM1079-i1-1.1_000534 797515.HMPREF9103_02537 2.2e-54 218.0 Lactobacillaceae ysxB ko:K07584 ko00000 Bacteria 1VEQ9@1239,3F839@33958,4HNMV@91061,COG2868@1,COG2868@2 NA|NA|NA J Cysteine protease Prp gnl|extdb|FAM1079-i1-1.1_000535 797515.HMPREF9103_02538 7.9e-48 196.1 Lactobacillaceae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6HW@1239,3F6WU@33958,4HIMN@91061,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family gnl|extdb|FAM1079-i1-1.1_000536 797515.HMPREF9103_02539 2.9e-99 367.9 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F422@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase gnl|extdb|FAM1079-i1-1.1_000537 797515.HMPREF9103_02540 9.4e-74 282.7 Lactobacillaceae yqhY ko:K10947 ko00000,ko03000 Bacteria 1V4IC@1239,3F71X@33958,4HJ7T@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function gnl|extdb|FAM1079-i1-1.1_000538 797515.HMPREF9103_02541 4.6e-70 270.4 Lactobacillaceae nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1VA9B@1239,3F7KW@33958,4HKMU@91061,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons gnl|extdb|FAM1079-i1-1.1_000539 797515.HMPREF9103_02542 2.2e-159 568.2 Lactobacillaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1P@1239,3F46A@33958,4H9Q6@91061,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate gnl|extdb|FAM1079-i1-1.1_000540 797515.HMPREF9103_02543 1.5e-239 835.1 Lactobacillaceae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP4E@1239,3F4RE@33958,4HAN2@91061,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides gnl|extdb|FAM1079-i1-1.1_000541 797515.HMPREF9103_02544 2.5e-40 171.0 Lactobacillaceae xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1VK9I@1239,3F81K@33958,4HNRB@91061,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides gnl|extdb|FAM1079-i1-1.1_000542 797515.HMPREF9103_02545 8e-171 606.3 Lactobacillaceae ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TPQY@1239,3F436@33958,4HA8E@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family gnl|extdb|FAM1079-i1-1.1_000543 797515.HMPREF9103_02546 5.8e-149 533.5 Lactobacillaceae rrmJ 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1TPE4@1239,3F45T@33958,4HAPY@91061,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J gnl|extdb|FAM1079-i1-1.1_000544 797515.HMPREF9103_02547 2.8e-76 291.2 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,3F71C@33958,4HFY8@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes gnl|extdb|FAM1079-i1-1.1_000545 797515.HMPREF9103_02548 1e-309 1068.5 Lactobacillaceae recN GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 1TP99@1239,3F43U@33958,4H9ZR@91061,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA gnl|extdb|FAM1079-i1-1.1_000547 797515.HMPREF9103_02550 2.8e-111 407.9 Lactobacillaceae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15680 Bacteria 1TP0M@1239,3F3X9@33958,4HAYW@91061,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP gnl|extdb|FAM1079-i1-1.1_000548 797515.HMPREF9103_02551 1.1e-30 138.7 Lactobacillaceae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1VK74@1239,3F81N@33958,4HNHS@91061,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gnl|extdb|FAM1079-i1-1.1_000549 797515.HMPREF9103_02552 4e-207 727.2 Lactobacillaceae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPP3@1239,3F3XX@33958,4HAK8@91061,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine gnl|extdb|FAM1079-i1-1.1_000550 797515.HMPREF9103_02553 0.0 1594.7 Lactobacillaceae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TNYB@1239,3F3N8@33958,4H9WW@91061,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA gnl|extdb|FAM1079-i1-1.1_000552 797515.HMPREF9103_02555 2e-252 877.9 Lactobacillaceae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TP3N@1239,3F45F@33958,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA gnl|extdb|FAM1079-i1-1.1_000553 797515.HMPREF9103_02556 4.4e-135 487.3 Lactobacillaceae stp 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1V6K5@1239,3F4UI@33958,4HCDR@91061,COG0631@1,COG0631@2 NA|NA|NA T phosphatase gnl|extdb|FAM1079-i1-1.1_000554 797515.HMPREF9103_02557 0.0 1275.8 Lactobacillaceae prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1TP3F@1239,3F4G6@33958,4H9KD@91061,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT serine threonine protein kinase gnl|extdb|FAM1079-i1-1.1_000555 797515.HMPREF9103_02558 1.8e-167 595.1 Lactobacillaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TPSQ@1239,3F3XH@33958,4HA9W@91061,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit gnl|extdb|FAM1079-i1-1.1_000556 797515.HMPREF9103_02559 1.1e-118 432.6 Lactobacillaceae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,3F4KX@33958,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family gnl|extdb|FAM1079-i1-1.1_000557 797515.HMPREF9103_02560 1.6e-125 455.3 Lactobacillaceae thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VA0W@1239,3F4N8@33958,4HHS1@91061,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase gnl|extdb|FAM1079-i1-1.1_000558 797515.HMPREF9103_02562 1.4e-110 405.6 Lactobacillaceae XK27_09620 Bacteria 1TT2S@1239,3F544@33958,4HBQI@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase gnl|extdb|FAM1079-i1-1.1_000559 797515.HMPREF9103_02563 2.3e-229 801.2 Lactobacillaceae XK27_09615 Bacteria 1TPRA@1239,3F44U@33958,4HDA5@91061,COG0431@1,COG0431@2,COG2461@1,COG2461@2 NA|NA|NA S reductase gnl|extdb|FAM1079-i1-1.1_000560 797515.HMPREF9103_02565 1.1e-26 125.2 Lactobacillaceae rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEI2@1239,3F7ZN@33958,4HNIK@91061,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family gnl|extdb|FAM1079-i1-1.1_000561 797515.HMPREF9103_02566 1.4e-57 228.8 Lactobacillaceae asp Bacteria 1V731@1239,3F72W@33958,4HIS4@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function gnl|extdb|FAM1079-i1-1.1_000562 797515.HMPREF9103_02567 1.7e-283 981.5 Lactobacillaceae yloV ko:K07030 ko00000 Bacteria 1TQMX@1239,3F3X0@33958,4HBSE@91061,COG1461@1,COG1461@2 NA|NA|NA S DAK2 domain fusion protein YloV gnl|extdb|FAM1079-i1-1.1_000563 797515.HMPREF9103_02569 0.0 1305.4 Lactobacillaceae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TQ6I@1239,3F3JW@33958,4HAWN@91061,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) gnl|extdb|FAM1079-i1-1.1_000564 797515.HMPREF9103_02570 6.2e-188 663.3 Lactobacillaceae plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPXS@1239,3F4N9@33958,4HA0R@91061,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA gnl|extdb|FAM1079-i1-1.1_000565 797515.HMPREF9103_02571 3.4e-36 157.1 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VEE3@1239,3F7F4@33958,4HNQ0@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis gnl|extdb|FAM1079-i1-1.1_000566 797515.HMPREF9103_02572 1.9e-127 461.8 Lactobacillaceae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1TPGC@1239,3F564@33958,4HAWU@91061,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism gnl|extdb|FAM1079-i1-1.1_000567 797515.HMPREF9103_02573 0.0 1962.2 Lactobacillaceae smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,3F478@33958,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning gnl|extdb|FAM1079-i1-1.1_000568 797515.HMPREF9103_02574 4.7e-186 657.5 Lactobacillaceae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,3F3YC@33958,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) gnl|extdb|FAM1079-i1-1.1_000569 797515.HMPREF9103_02575 2.9e-57 227.6 Lactobacillaceae ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 ko:K09787 ko00000 Bacteria 1VEGP@1239,3F7FG@33958,4HKK6@91061,COG2739@1,COG2739@2 NA|NA|NA S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein gnl|extdb|FAM1079-i1-1.1_000570 797515.HMPREF9103_02576 1.1e-216 759.2 Lactobacillaceae ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1TP06@1239,3F40R@33958,4H9T4@91061,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY gnl|extdb|FAM1079-i1-1.1_000571 797515.HMPREF9103_02577 2.9e-44 184.1 Lactobacillaceae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA0X@1239,3F6VV@33958,4HKNN@91061,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family gnl|extdb|FAM1079-i1-1.1_000572 797515.HMPREF9103_02578 1.5e-39 168.3 Lactobacillaceae ylqC ko:K06960 ko00000 Bacteria 1VEG7@1239,3F829@33958,4HNX0@91061,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family gnl|extdb|FAM1079-i1-1.1_000573 797515.HMPREF9103_02579 7e-95 353.2 Lactobacillaceae rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1V6HD@1239,3F74P@33958,4HH3H@91061,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes gnl|extdb|FAM1079-i1-1.1_000575 797515.HMPREF9103_02581 1.1e-59 235.7 Lactobacillaceae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6FT@1239,3F6K4@33958,4HIK3@91061,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site gnl|extdb|FAM1079-i1-1.1_000576 797515.HMPREF9103_02582 8.3e-176 622.9 Lactobacillaceae xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TPQB@1239,3F44K@33958,4HARA@91061,COG4974@1,COG4974@2 NA|NA|NA D Belongs to the 'phage' integrase family. XerC subfamily gnl|extdb|FAM1079-i1-1.1_000577 797515.HMPREF9103_02583 4.6e-94 350.5 Lactobacillaceae hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 ko00000,ko01000,ko01002 Bacteria 1TPXK@1239,3F4HS@33958,4H9PD@91061,COG5405@1,COG5405@2 NA|NA|NA O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery gnl|extdb|FAM1079-i1-1.1_000578 797515.HMPREF9103_02584 2.9e-257 894.0 Lactobacillaceae hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03667 ko00000,ko03110 Bacteria 1TPKQ@1239,3F3WB@33958,4HA83@91061,COG1220@1,COG1220@2 NA|NA|NA O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis gnl|extdb|FAM1079-i1-1.1_000579 797515.HMPREF9103_02585 1.3e-167 595.5 Lactobacillaceae lacX 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1U26T@1239,3F3KT@33958,4HA4J@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase gnl|extdb|FAM1079-i1-1.1_000580 797515.HMPREF9103_02586 8.6e-108 396.4 Lactobacillaceae plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,3.5.1.104 ko:K08591,ko:K22278 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VA3J@1239,3F543@33958,4HC55@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP gnl|extdb|FAM1079-i1-1.1_000581 797515.HMPREF9103_02587 0.0 1263.4 Lactobacillaceae parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQCF@1239,3F430@33958,4H9UC@91061,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule gnl|extdb|FAM1079-i1-1.1_000582 797515.HMPREF9103_02588 0.0 1584.3 Lactobacillaceae parC GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TRE7@1239,3F3MJ@33958,4HAQB@91061,COG0188@1,COG0188@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule gnl|extdb|FAM1079-i1-1.1_000583 797515.HMPREF9103_02589 4.5e-177 627.1 Lactobacillaceae Bacteria 1UYRT@1239,3FBIB@33958,4IQQ1@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain gnl|extdb|FAM1079-i1-1.1_000584 797515.HMPREF9103_02590 9.8e-169 599.4 Lactobacillaceae ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TPH6@1239,3F3PJ@33958,4H9T8@91061,COG1227@1,COG1227@2 NA|NA|NA C inorganic pyrophosphatase gnl|extdb|FAM1079-i1-1.1_000585 1423743.JCM14108_1697 7.5e-63 246.5 Lactobacillaceae msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1UPN0@1239,3F6H4@33958,4HGWN@91061,COG0229@1,COG0229@2 NA|NA|NA O peptide methionine sulfoxide reductase gnl|extdb|FAM1079-i1-1.1_000586 797515.HMPREF9103_02592 9.4e-100 369.4 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TQ3E@1239,3F3YI@33958,4HAIV@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine gnl|extdb|FAM1079-i1-1.1_000461 797515.HMPREF9103_00102 5.9e-55 219.9 Lactobacillaceae Bacteria 1U6G7@1239,2C86H@1,30AC5@2,3F7UM@33958,4IG8A@91061 NA|NA|NA S Protein of unknown function (DUF1516) gnl|extdb|FAM1079-i1-1.1_000505 797515.HMPREF9103_00892 1.4e-32 145.6 Lactobacillaceae acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 1VEM9@1239,3F81R@33958,4HNN7@91061,COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family gnl|extdb|FAM1079-i1-1.1_000551 797515.HMPREF9103_02554 6.1e-163 580.1 Lactobacillaceae fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 iSB619.SA_RS06010 Bacteria 1TQ32@1239,3F4N7@33958,4HART@91061,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus gnl|extdb|FAM1079-i1-1.1_000574 797515.HMPREF9103_02580 3.5e-151 540.8 Lactobacillaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,3F3NP@33958,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family gnl|extdb|FAM1079-i1-1.1_000589 797515.HMPREF9103_00867 1.2e-58 232.3 Lactobacillaceae Bacteria 1U5VQ@1239,3F6KH@33958,4IFJH@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain gnl|extdb|FAM1079-i1-1.1_000590 797515.HMPREF9103_00866 3.8e-99 367.5 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1V56K@1239,3F54I@33958,4HTPS@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase gnl|extdb|FAM1079-i1-1.1_000591 797515.HMPREF9103_00865 1e-240 839.0 Lactobacillaceae pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 ko:K03458,ko:K16169,ko:K16170 ko00000,ko02000 2.A.40,2.A.40.3.1,2.A.40.3.2 iSB619.SA_RS02140 Bacteria 1TNZZ@1239,3F3Y7@33958,4HBAM@91061,COG2233@1,COG2233@2 NA|NA|NA F xanthine permease gnl|extdb|FAM1079-i1-1.1_000592 797515.HMPREF9103_00864 0.0 1213.0 Lactobacillaceae Bacteria 1UYFY@1239,3F5UM@33958,4HFAH@91061,COG4934@1,COG4934@2 NA|NA|NA O Pro-kumamolisin, activation domain gnl|extdb|FAM1079-i1-1.1_000593 797515.HMPREF9103_00863 1.9e-172 611.7 Lactobacillaceae Bacteria 1TTAM@1239,3FC6M@33958,4HFT5@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000594 797515.HMPREF9103_00862 0.0 1573.1 Lactobacillaceae treP 2.4.1.64 ko:K05342 ko00500,ko01100,map00500,map01100 R02727 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic gnl|extdb|FAM1079-i1-1.1_000595 797515.HMPREF9103_00861 4.4e-80 303.9 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,3FBR5@33958,4HN5H@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes gnl|extdb|FAM1079-i1-1.1_000596 525318.HMPREF0497_0741 3.2e-176 624.4 Lactobacillaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.7.2.2 ko:K00611,ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00220,map00230,map00910,map01100,map01110,map01120,map01130,map01200,map01230 M00029,M00844 R00150,R01395,R01398 RC00002,RC00043,RC00096,RC02803,RC02804 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPF2@1239,3F48K@33958,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline gnl|extdb|FAM1079-i1-1.1_000597 797515.HMPREF9103_00858 1.6e-120 438.7 Lactobacillaceae gph GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 ko:K01091,ko:K07025 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V6BF@1239,3FC9Y@33958,4HHZW@91061,COG0546@1,COG0546@2 NA|NA|NA S haloacid dehalogenase-like hydrolase gnl|extdb|FAM1079-i1-1.1_000598 1400520.LFAB_14015 9.1e-33 146.7 Lactobacillaceae sigM ko:K03088 ko00000,ko03021 Bacteria 1V5Z4@1239,3F7VY@33958,4HK72@91061,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 gnl|extdb|FAM1079-i1-1.1_000599 511437.Lbuc_0145 1.4e-82 313.2 Lactobacillaceae Bacteria 1V1V7@1239,28Q2Q@1,2ZCKK@2,3F68V@33958,4HGPP@91061 NA|NA|NA S Sigma factor regulator N-terminal gnl|extdb|FAM1079-i1-1.1_000600 797515.HMPREF9103_00857 7.9e-60 236.1 Lactobacillaceae ko:K09004 ko00000 Bacteria 1VEYT@1239,3F7R7@33958,4HP12@91061,COG1416@1,COG1416@2 NA|NA|NA S DsrE/DsrF-like family gnl|extdb|FAM1079-i1-1.1_000601 797515.HMPREF9103_00856 3.8e-273 946.8 Lactobacillaceae Bacteria 1UCBA@1239,3F3JA@33958,4HBCI@91061,COG4320@1,COG4320@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2252) gnl|extdb|FAM1079-i1-1.1_000602 525318.HMPREF0497_0748 2.9e-86 324.7 Lactobacillaceae ogt 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 ko00000,ko01000,ko03000,ko03400 Bacteria 1VA03@1239,3F6RF@33958,4HETA@91061,COG0350@1,COG0350@2 NA|NA|NA L Methyltransferase gnl|extdb|FAM1079-i1-1.1_000603 797515.HMPREF9103_00853 5.4e-158 563.5 Lactobacillaceae Bacteria 1UYTY@1239,2E39Q@1,2ZBHZ@2,3FC0T@33958,4IVCP@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000604 797515.HMPREF9103_00852 7.1e-74 283.1 Lactobacillaceae Bacteria 1VEC4@1239,3F654@33958,4HM2F@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000606 797515.HMPREF9103_00849 9.2e-218 763.1 Lactobacillaceae rny ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,3F3JT@33958,4HC9J@91061,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay gnl|extdb|FAM1079-i1-1.1_000608 797515.HMPREF9103_00847 3.1e-24 119.0 Lactobacillaceae Bacteria 1U7GX@1239,29XME@1,30B3I@2,3F9NF@33958,4IHDC@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000610 797515.HMPREF9103_00846 2.6e-307 1060.4 Lactobacillaceae cpdB 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3FC1Z@33958,4H9VJ@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family gnl|extdb|FAM1079-i1-1.1_000611 797515.HMPREF9103_00844 2e-248 865.1 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter gnl|extdb|FAM1079-i1-1.1_000612 797515.HMPREF9103_00843 1.6e-64 251.9 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6HJ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress gnl|extdb|FAM1079-i1-1.1_000614 797515.HMPREF9103_00841 7.2e-194 682.9 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid gnl|extdb|FAM1079-i1-1.1_000616 797515.HMPREF9103_00611 9.5e-183 646.0 Lactobacillaceae iunH2 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSAR@1239,3F4A3@33958,4HDCS@91061,COG1957@1,COG1957@2 NA|NA|NA F nucleoside hydrolase gnl|extdb|FAM1079-i1-1.1_000617 525318.HMPREF0497_0760 2.5e-174 618.2 Lactobacillaceae Bacteria 1VDPM@1239,3F3NS@33958,4IRVW@91061,COG2339@1,COG2339@2 NA|NA|NA S Protease prsW family gnl|extdb|FAM1079-i1-1.1_000618 797515.HMPREF9103_00614 5.7e-183 646.7 Lactobacillaceae trxB1 1.18.1.2,1.19.1.1 ko:K21567 ko00000,ko01000 Bacteria 1TRPN@1239,3F3NQ@33958,4H9V7@91061,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase gnl|extdb|FAM1079-i1-1.1_000619 797515.HMPREF9103_00615 3e-134 484.6 Lactobacillaceae kcsA GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K10716 ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 1V4RU@1239,3FBTF@33958,4HHVV@91061,COG1226@1,COG1226@2 NA|NA|NA P Ion channel gnl|extdb|FAM1079-i1-1.1_000620 797515.HMPREF9103_00616 0.0 1355.9 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily gnl|extdb|FAM1079-i1-1.1_000621 797515.HMPREF9103_00618 3.6e-125 454.1 Lactobacillaceae pgm3 Bacteria 1TQWQ@1239,3FC5N@33958,4HV9J@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family gnl|extdb|FAM1079-i1-1.1_000622 797515.HMPREF9103_00619 9.6e-71 272.7 Bacteria yjcF ko:K02348 ko00000 Bacteria COG2153@1,COG2153@2 NA|NA|NA K protein acetylation gnl|extdb|FAM1079-i1-1.1_000623 797515.HMPREF9103_00620 2.1e-218 764.6 Lactobacillaceae Bacteria 1V7GP@1239,3F42R@33958,4HJ4R@91061,COG1835@1,COG1835@2 NA|NA|NA I transferase activity, transferring acyl groups other than amino-acyl groups gnl|extdb|FAM1079-i1-1.1_000624 797515.HMPREF9103_00621 1.4e-83 315.5 Lactobacillaceae iap ko:K19224,ko:K21471 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 1V9ZW@1239,3F6NS@33958,4HH84@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC P60 family gnl|extdb|FAM1079-i1-1.1_000625 797515.HMPREF9103_00623 0.0 1488.4 Lactobacillaceae ydgH ko:K06994,ko:K07003 ko00000 Bacteria 1TQ7C@1239,3FCCY@33958,4HBM6@91061,COG2409@1,COG2409@2 NA|NA|NA S MMPL family gnl|extdb|FAM1079-i1-1.1_000626 797515.HMPREF9103_00624 5.5e-178 630.2 Lactobacillaceae pacA 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein gnl|extdb|FAM1079-i1-1.1_000627 797515.HMPREF9103_00625 2.9e-108 397.9 Lactobacillaceae ko:K02395 ko00000,ko02035 Bacteria 1V7JY@1239,3F6JN@33958,4I28S@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gnl|extdb|FAM1079-i1-1.1_000629 797515.HMPREF9103_00627 1.5e-55 221.9 Lactobacillaceae trxA ko:K03619,ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F7I4@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family gnl|extdb|FAM1079-i1-1.1_000630 797515.HMPREF9103_00628 1e-63 249.2 Lactobacillaceae Bacteria 1U66I@1239,29P6C@1,30A4G@2,3F76T@33958,4IFWT@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000631 797515.HMPREF9103_00629 4e-77 294.3 Lactobacillaceae ko:K03824 ko00000,ko01000 Bacteria 1V3PW@1239,3F6DM@33958,4HGZK@91061,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) family gnl|extdb|FAM1079-i1-1.1_000633 797515.HMPREF9103_00632 2.7e-121 441.8 Lactobacillaceae Bacteria 1VWGD@1239,2F31P@1,33VWT@2,3F4CP@33958,4HWD9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000635 797515.HMPREF9103_00634 0.0 1093.2 Lactobacillaceae ycfI GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000636 797515.HMPREF9103_00635 2.5e-112 411.4 Lactobacillaceae Bacteria 1U5NN@1239,3F684@33958,4IFD7@91061,COG4832@1,COG4832@2 NA|NA|NA S Psort location Cytoplasmic, score gnl|extdb|FAM1079-i1-1.1_000637 797515.HMPREF9103_00636 3.1e-181 641.0 Lactobacillaceae GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008 Bacteria 1TPIY@1239,3F40K@33958,4HA4Q@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_000638 797515.HMPREF9103_00637 9.2e-186 656.0 Lactobacillaceae guaC 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS06660 Bacteria 1TNYF@1239,3F45K@33958,4HA55@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides gnl|extdb|FAM1079-i1-1.1_000639 797515.HMPREF9103_00638 6.6e-248 862.8 Lactobacillaceae purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4C@1239,3F3RQ@33958,4H9YT@91061,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP gnl|extdb|FAM1079-i1-1.1_000640 797515.HMPREF9103_00640 1.7e-248 864.8 Lactobacillaceae purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095 Bacteria 1TPMM@1239,3F48P@33958,4HACW@91061,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily gnl|extdb|FAM1079-i1-1.1_000641 797515.HMPREF9103_00641 1.1e-122 446.0 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VR9G@1239,3F3TR@33958,4HV4W@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM1079-i1-1.1_000643 797515.HMPREF9103_00645 8.5e-151 539.7 Lactobacillaceae 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 Bacteria 1W3JS@1239,3FB6M@33958,4I1FX@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold gnl|extdb|FAM1079-i1-1.1_000644 797515.HMPREF9103_00646 1.3e-119 435.6 Lactobacillaceae Bacteria 1V8E3@1239,3F4H9@33958,4HJ08@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane gnl|extdb|FAM1079-i1-1.1_000645 797515.HMPREF9103_00647 1.3e-113 415.6 Lactobacillaceae Bacteria 1UKTT@1239,3F60N@33958,4HZHQ@91061,COG3322@1,COG3322@2 NA|NA|NA T CHASE4 domain gnl|extdb|FAM1079-i1-1.1_000646 797515.HMPREF9103_00648 2.1e-28 131.0 Lactobacillaceae Bacteria 1U6T9@1239,29PN2@1,30AK8@2,3F8GA@33958,4IGM2@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000648 797515.HMPREF9103_00650 8.7e-300 1035.4 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate gnl|extdb|FAM1079-i1-1.1_000649 797515.HMPREF9103_01442 7.1e-72 276.6 Lactobacillaceae Bacteria 1VFXH@1239,2DNYJ@1,32ZT4@2,3F6B5@33958,4HPEG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000650 797515.HMPREF9103_01441 1.6e-263 914.8 Lactobacillaceae rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP4H@1239,3F4GQ@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family gnl|extdb|FAM1079-i1-1.1_000651 797515.HMPREF9103_01438 8.7e-164 582.8 Lactobacillaceae yvgN Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_000652 1071400.LBUCD034_0560 3.9e-60 237.7 Lactobacillaceae ko:K03828 ko00000,ko01000 Bacteria 1UIWB@1239,3F6WR@33958,4HM7D@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) family gnl|extdb|FAM1079-i1-1.1_000653 797515.HMPREF9103_01436 2.5e-155 554.7 Lactobacillaceae yneD Bacteria 1TQDY@1239,3FBSM@33958,4HBS5@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM1079-i1-1.1_000654 797515.HMPREF9103_01433 7.3e-141 506.5 Lactobacillaceae thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1R6@1239,3F43J@33958,4HFTJ@91061,COG2145@1,COG2145@2 NA|NA|NA H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) gnl|extdb|FAM1079-i1-1.1_000655 525318.HMPREF0497_0808 5.6e-136 490.3 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase gnl|extdb|FAM1079-i1-1.1_000656 797515.HMPREF9103_01431 4.2e-110 404.1 Lactobacillaceae thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3ZR@1239,3F5ZQ@33958,4HH1E@91061,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) gnl|extdb|FAM1079-i1-1.1_000657 797515.HMPREF9103_01430 2e-160 571.6 Lactobacillaceae Bacteria 1U5GZ@1239,2BXPD@1,309Q4@2,3F5XE@33958,4IF7S@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000658 797515.HMPREF9103_01429 7.7e-145 520.0 Lactobacillaceae Bacteria 1U6PJ@1239,29PJJ@1,30AHQ@2,3F89A@33958,4IGGI@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000659 797515.HMPREF9103_01428 8.9e-247 859.4 Lactobacillaceae Bacteria 1W4G9@1239,2FCGI@1,2ZQRU@2,3F61K@33958,4I16N@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000660 1423743.JCM14108_1675 1.2e-101 376.3 Lactobacillaceae 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 1TP2Q@1239,3F4NB@33958,4HCKS@91061,COG1120@1,COG1120@2 NA|NA|NA HP ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000661 525318.HMPREF0497_0813 7.3e-114 417.2 Lactobacillaceae fhuB ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TPX6@1239,3F4T9@33958,4H9QQ@91061,COG0609@1,COG0609@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM1079-i1-1.1_000662 797515.HMPREF9103_01423 1.7e-174 618.6 Lactobacillaceae fhuG ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TPX6@1239,3FCBP@33958,4HAM8@91061,COG0609@1,COG0609@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM1079-i1-1.1_000663 797515.HMPREF9103_01422 6e-161 573.5 Lactobacillaceae fhuD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TQMK@1239,3F4YN@33958,4HBP4@91061,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein gnl|extdb|FAM1079-i1-1.1_000664 1423743.JCM14108_1682 0.0 1086.2 Lactobacillaceae macB3 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBJ@1239,3F44P@33958,4HBK7@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000665 797515.HMPREF9103_01419 1.4e-80 305.4 Lactobacillaceae Bacteria 1U686@1239,2CHFK@1,30A5K@2,3F7A8@33958,4IFYX@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000666 797515.HMPREF9103_01418 1.6e-58 231.9 Lactobacillaceae Bacteria 1VPXU@1239,2EGA1@1,33A1U@2,3F7WK@33958,4HS3Y@91061 NA|NA|NA S Protein of unknown function (DUF1516) gnl|extdb|FAM1079-i1-1.1_000667 797515.HMPREF9103_01417 7e-74 283.1 Lactobacillaceae Bacteria 1VX0V@1239,2F603@1,33YIJ@2,3F6YU@33958,4HXF9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000668 797515.HMPREF9103_01416 1.7e-287 994.6 Lactobacillaceae ubiD 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ6V@1239,3F50J@33958,4HM1D@91061,COG0043@1,COG0043@2 NA|NA|NA H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase gnl|extdb|FAM1079-i1-1.1_000669 60520.HR47_03440 3.6e-81 307.8 Lactobacillaceae ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3JV@1239,3F5PD@33958,4HFZX@91061,COG0163@1,COG0163@2 NA|NA|NA H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN gnl|extdb|FAM1079-i1-1.1_000670 797515.HMPREF9103_01413 7e-156 556.6 Lactobacillaceae ko:K09681 ko00000,ko03000 Bacteria 1TQ6Y@1239,3F4CY@33958,4HWQQ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain gnl|extdb|FAM1079-i1-1.1_000671 797515.HMPREF9103_01412 1.7e-103 382.5 Lactobacillaceae ko:K19224,ko:K21471 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 1VG0Z@1239,3F50V@33958,4HBE9@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC P60 family protein gnl|extdb|FAM1079-i1-1.1_000672 797515.HMPREF9103_01411 1.1e-113 416.0 Lactobacillaceae Bacteria 1V3AX@1239,3F9SJ@33958,4IHFV@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family gnl|extdb|FAM1079-i1-1.1_000673 797515.HMPREF9103_01410 3.8e-66 257.3 Lactobacillaceae Bacteria 1V3SS@1239,3F6UD@33958,4HI9G@91061,COG1942@1,COG1942@2 NA|NA|NA S Tautomerase enzyme gnl|extdb|FAM1079-i1-1.1_000674 797515.HMPREF9103_01409 1.1e-225 788.9 Lactobacillaceae fdh 1.17.1.9 ko:K00122 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 R00519 RC02796 ko00000,ko00001,ko01000 Bacteria 1V122@1239,3F4ZM@33958,4HDD3@91061,COG1052@1,COG1052@2 NA|NA|NA C Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms gnl|extdb|FAM1079-i1-1.1_000675 797515.HMPREF9103_01408 1.4e-246 859.4 Lactobacillaceae Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2,COG4886@1,COG4886@2 NA|NA|NA M Bacterial Ig-like domain (group 3) gnl|extdb|FAM1079-i1-1.1_000676 525318.HMPREF0497_0835 1.4e-40 172.2 Lactobacillaceae Bacteria 1U7N5@1239,29Q7W@1,30B6X@2,3F9XS@33958,4IHJF@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000677 525318.HMPREF0497_1187 1.3e-09 67.8 Lactobacillaceae Bacteria 1W51C@1239,2DG6I@1,2ZUQQ@2,3F8SJ@33958,4IGU7@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000678 525318.HMPREF0497_0836 1.3e-228 798.9 Lactobacillaceae Bacteria 1VSAB@1239,3FCCN@33958,4HECQ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000680 203123.OEOE_1494 3.9e-137 494.6 Leuconostocaceae ko:K07497 ko00000 Bacteria 1U3DM@1239,4AXMR@81850,4ID5Z@91061,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_000681 1302286.BAOT01000008_gene597 8.7e-99 366.7 Lactobacillaceae Bacteria 1TRQP@1239,3F562@33958,4HCUQ@91061,COG1783@1,COG1783@2 NA|NA|NA S Terminase RNAseH like domain gnl|extdb|FAM1079-i1-1.1_000682 1140002.I570_01447 1.9e-19 102.1 Enterococcaceae Bacteria 1TZWU@1239,2BM4Y@1,32FNE@2,4B3TF@81852,4I96A@91061 NA|NA|NA S Helix-turn-helix of insertion element transposase gnl|extdb|FAM1079-i1-1.1_000683 762968.HMPREF9441_00533 6.6e-11 74.3 Bacteroidetes ko:K07451 ko00000,ko01000,ko02048 Bacteria 4P6AH@976,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease gnl|extdb|FAM1079-i1-1.1_000684 1138822.PL11_06645 4e-25 121.3 Lactobacillaceae Bacteria 1VMGI@1239,2E42J@1,32YZ1@2,3F8JP@33958,4HRUN@91061 NA|NA|NA S Transcriptional regulator, RinA family gnl|extdb|FAM1079-i1-1.1_000688 1423724.BAMM01000020_gene1816 7.4e-20 102.8 Lactobacillaceae Bacteria 1W3JH@1239,29C1X@1,2ZZ0E@2,3F8BR@33958,4I1E9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000690 511437.Lbuc_1535 3.8e-32 144.4 Lactobacillaceae Bacteria 1VKPB@1239,2EGZP@1,33ART@2,3F8RA@33958,4HR69@91061 NA|NA|NA S YopX protein gnl|extdb|FAM1079-i1-1.1_000692 1423743.JCM14108_2653 7.7e-14 83.6 Lactobacillaceae Bacteria 1U5U4@1239,29NY6@1,309WA@2,3F6IC@33958,4IFI2@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000695 543734.LCABL_11000 1e-32 146.0 Lactobacillaceae Bacteria 1VA3C@1239,2DJ23@1,32UC6@2,3F7VB@33958,4HPYG@91061 NA|NA|NA S VRR_NUC gnl|extdb|FAM1079-i1-1.1_000696 1423755.BAML01000004_gene401 5e-139 501.1 Lactobacillaceae Bacteria 1TQNX@1239,3F4EZ@33958,4HCHZ@91061,COG5545@1,COG5545@2 NA|NA|NA S Virulence-associated protein E gnl|extdb|FAM1079-i1-1.1_000697 1423815.BACR01000010_gene574 2.6e-82 312.0 Lactobacillaceae Bacteria 1V4PM@1239,3F3RI@33958,4HHZK@91061,COG3378@1,COG3378@2 NA|NA|NA S Bifunctional DNA primase/polymerase, N-terminal gnl|extdb|FAM1079-i1-1.1_000698 1231336.L248_1664 1.2e-43 183.0 Lactobacillaceae Bacteria 1VDGZ@1239,2C0B0@1,32WZE@2,3F79D@33958,4HMDG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000699 1567453.A0A0A1ENB5_9CAUD 6.5e-78 297.4 Siphoviridae Viruses 4QCJP@10239,4QKTS@10699,4QTX1@28883 NA|NA|NA S AAA domain gnl|extdb|FAM1079-i1-1.1_000700 1567453.A0A0A1ENT0_9CAUD 1.2e-175 622.9 Siphoviridae Viruses 4QB5I@10239,4QKRP@10699,4QPQ9@28883 NA|NA|NA S helicase activity gnl|extdb|FAM1079-i1-1.1_000701 272626.lin2591 3.6e-21 108.2 Listeriaceae Bacteria 1VC9N@1239,26KK1@186820,2E5K5@1,330BC@2,4HM43@91061 NA|NA|NA S Siphovirus Gp157 gnl|extdb|FAM1079-i1-1.1_000705 511437.Lbuc_1552 3.4e-18 97.1 Lactobacillaceae Bacteria 1U6BZ@1239,2A5KR@1,30UB8@2,3F7JT@33958,4IG3M@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000706 349161.Dred_2622 3.8e-60 238.0 Clostridia ko:K14623 ko00000,ko03400 Bacteria 1VUFB@1239,24KSB@186801,COG3617@1,COG3617@2 NA|NA|NA K BRO family, N-terminal domain gnl|extdb|FAM1079-i1-1.1_000707 1423734.JCM14202_3081 2.4e-11 74.3 Lactobacillaceae Bacteria 1U71B@1239,29PTX@1,30AS3@2,3F8UQ@33958,4IGVS@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000708 1423743.JCM14108_2664 4.5e-13 80.1 Lactobacillaceae Bacteria 1U6D9@1239,2A552@1,30TTU@2,3F7N9@33958,4IG50@91061 NA|NA|NA S YozE SAM-like fold gnl|extdb|FAM1079-i1-1.1_000709 1423743.JCM14108_2665 5e-11 73.2 Lactobacillaceae Bacteria 1U6DV@1239,29PBW@1,30AA3@2,3F7P6@33958,4IG5J@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000712 1423734.JCM14202_3082 2.3e-24 118.2 Lactobacillaceae ps115 Bacteria 1VEP9@1239,3F871@33958,4HPCR@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_000713 1423732.BALS01000070_gene2074 5.4e-21 107.5 Bacilli Bacteria 1W1K0@1239,4I17Z@91061,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase gnl|extdb|FAM1079-i1-1.1_000714 1423780.LOT_1614 7.5e-88 330.5 Bacilli Bacteria 1W2AH@1239,2CCD7@1,2ZWVQ@2,4I12M@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000715 862514.HMPREF0623_1544 1.3e-29 136.3 Lactobacillaceae Bacteria 1VW0M@1239,2EDPB@1,337J0@2,3F571@33958,4HW5R@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000716 1033837.WANG_1726 8.8e-184 649.4 Lactobacillaceae Bacteria 1TRSF@1239,3F3UG@33958,4HDM3@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase, catalytic core gnl|extdb|FAM1079-i1-1.1_000720 797515.HMPREF9103_02886 8e-140 503.1 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase gnl|extdb|FAM1079-i1-1.1_000721 797515.HMPREF9103_02888 1.1e-81 309.3 Lactobacillaceae Bacteria 1U5Q0@1239,2ADA1@1,312ZA@2,3F6AG@33958,4IFEA@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000722 797515.HMPREF9103_02889 0.0 1167.9 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM1079-i1-1.1_000723 797515.HMPREF9103_02890 2.3e-72 278.1 Lactobacillaceae Z012_06975 Bacteria 1UW8V@1239,3F8DU@33958,4I489@91061,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) gnl|extdb|FAM1079-i1-1.1_000724 1114972.AUAW01000027_gene720 1.3e-08 64.3 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_000605 797515.HMPREF9103_00851 7.7e-185 652.9 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta gnl|extdb|FAM1079-i1-1.1_000613 797515.HMPREF9103_00842 7.9e-151 539.7 Lactobacillaceae XK27_02985 Bacteria 1TR2E@1239,3FC89@33958,4HGA9@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase gnl|extdb|FAM1079-i1-1.1_000628 797515.HMPREF9103_00626 4e-128 464.2 Lactobacillaceae terC ko:K05794 ko00000 Bacteria 1TQ09@1239,3FB69@33958,4HI9A@91061,COG0861@1,COG0861@2 NA|NA|NA P integral membrane protein, YkoY family gnl|extdb|FAM1079-i1-1.1_000632 797515.HMPREF9103_00631 3.2e-67 261.5 Lactobacillaceae Bacteria 1V773@1239,3F3JQ@33958,4HIJG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein gnl|extdb|FAM1079-i1-1.1_000634 797515.HMPREF9103_00633 0.0 1172.1 Lactobacillaceae yfiC ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_000642 797515.HMPREF9103_00642 4.7e-34 149.8 Lactobacillaceae ko:K19157 ko00000,ko01000,ko02048 Bacteria 1U69Z@1239,3F7EP@33958,4IG17@91061,COG3041@1,COG3041@2 NA|NA|NA S Bacterial toxin of type II toxin-antitoxin system, YafQ gnl|extdb|FAM1079-i1-1.1_000647 797515.HMPREF9103_00649 1e-37 162.2 Lactobacillaceae Bacteria 1U6VB@1239,2BBKG@1,3254B@2,3F8JF@33958,4IGP7@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000679 525318.HMPREF0497_0837 7.8e-52 209.9 Lactobacillaceae feoA ko:K04758 ko00000,ko02000 Bacteria 1VEHC@1239,3F729@33958,4HPFS@91061,COG1918@1,COG1918@2 NA|NA|NA P FeoA gnl|extdb|FAM1079-i1-1.1_000702 1122143.AUEG01000005_gene1446 2.3e-11 74.7 Carnobacteriaceae ko:K07726 ko00000,ko03000 Bacteria 1UIZ9@1239,27HNG@186828,4HR4Y@91061,COG2944@1,COG2944@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_000726 525318.HMPREF0497_0419 1.8e-184 652.1 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F9B8@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family gnl|extdb|FAM1079-i1-1.1_000727 797515.HMPREF9103_01676 1.2e-137 495.7 Lactobacillaceae puuD ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F4PK@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S peptidase C26 gnl|extdb|FAM1079-i1-1.1_000728 797515.HMPREF9103_01675 2.4e-264 917.5 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family gnl|extdb|FAM1079-i1-1.1_000729 797515.HMPREF9103_01674 9.6e-104 382.9 Lactobacillaceae Bacteria 1U6AQ@1239,29P9F@1,30A7J@2,3F7GQ@33958,4IG25@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000730 797515.HMPREF9103_01673 0.0 1120.5 Lactobacillaceae mdlA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06148,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_000731 525318.HMPREF0497_0424 1.9e-309 1067.8 Lactobacillaceae mdlB GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008144,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0034040,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06147,ko:K18890 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_000732 797515.HMPREF9103_00814 4.5e-76 290.4 Lactobacillaceae hsp1 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F7DR@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family gnl|extdb|FAM1079-i1-1.1_000733 797515.HMPREF9103_00813 6.6e-72 276.6 Lactobacillaceae hsp1 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F7DR@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family gnl|extdb|FAM1079-i1-1.1_000734 797515.HMPREF9103_00812 3.5e-118 431.0 Lactobacillaceae Bacteria 1U67Q@1239,29P74@1,30A57@2,3F79H@33958,4IFY9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000735 797515.HMPREF9103_00811 1.1e-101 375.9 Lactobacillaceae Bacteria 1UYIP@1239,3FC4J@33958,4HJ4M@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_000739 797515.HMPREF9103_00806 6.2e-112 410.2 Lactobacillaceae Bacteria 1V011@1239,3FBCV@33958,4HWJY@91061,COG1814@1,COG1814@2 NA|NA|NA S VIT family gnl|extdb|FAM1079-i1-1.1_000740 797515.HMPREF9103_00805 7.5e-135 486.5 Lactobacillaceae nfrA 1.5.1.39 ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,3F4IY@33958,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase gnl|extdb|FAM1079-i1-1.1_000741 797515.HMPREF9103_00804 4.1e-113 414.1 Lactobacillaceae papP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TRU3@1239,3F3XD@33958,4HGE1@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter, permease protein gnl|extdb|FAM1079-i1-1.1_000742 797515.HMPREF9103_00803 5.6e-113 413.7 Lactobacillaceae ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TR7R@1239,3F45E@33958,4HGVA@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_000743 797515.HMPREF9103_00802 2.1e-134 485.0 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3FC3P@33958,4HDK7@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000744 797515.HMPREF9103_00801 4.6e-141 507.3 Lactobacillaceae cjaA ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F54P@33958,4HFBQ@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein gnl|extdb|FAM1079-i1-1.1_000745 797515.HMPREF9103_00800 8.8e-221 772.7 Lactobacillaceae ydiN GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015291,GO:0015292,GO:0016020,GO:0022804,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1V18N@1239,3FBEJ@33958,4IPXQ@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM1079-i1-1.1_000746 525318.HMPREF0497_0445 2.1e-81 308.9 Lactobacillaceae aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSPN@1239,3F4TX@33958,4HDMG@91061,COG0710@1,COG0710@2 NA|NA|NA E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate gnl|extdb|FAM1079-i1-1.1_000748 797515.HMPREF9103_00796 1.9e-192 678.3 Lactobacillaceae xynD GO:0005575,GO:0016020 3.5.1.104 ko:K22278 ko00000,ko01000 Bacteria 1V6DN@1239,3F50B@33958,4HEPH@91061,COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase gnl|extdb|FAM1079-i1-1.1_000749 797515.HMPREF9103_00794 5.1e-245 853.2 Lactobacillaceae Bacteria 1TQQ0@1239,3F4D3@33958,4HDKW@91061,COG1228@1,COG1228@2 NA|NA|NA Q Imidazolonepropionase and related amidohydrolases gnl|extdb|FAM1079-i1-1.1_000750 797515.HMPREF9103_00792 2.9e-45 187.6 Lactobacillaceae 5.4.99.5 ko:K04092,ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 1VK50@1239,3F8ZV@33958,4HPQX@91061,COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase type II gnl|extdb|FAM1079-i1-1.1_000751 797515.HMPREF9103_00791 1.2e-216 758.8 Lactobacillaceae aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976,iNJ661.Rv2540c Bacteria 1TQ40@1239,3F502@33958,4HA0H@91061,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system gnl|extdb|FAM1079-i1-1.1_000752 797515.HMPREF9103_00790 6.5e-243 846.3 Lactobacillaceae aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0345 Bacteria 1TPIH@1239,3F5B2@33958,4HBHZ@91061,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate gnl|extdb|FAM1079-i1-1.1_000753 797515.HMPREF9103_00789 1.4e-148 532.3 Lactobacillaceae tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 iYO844.BSU22610 Bacteria 1TPXG@1239,3F589@33958,4HBI4@91061,COG0287@1,COG0287@2 NA|NA|NA E prephenate dehydrogenase gnl|extdb|FAM1079-i1-1.1_000754 797515.HMPREF9103_00788 3e-87 327.8 Lactobacillaceae aroK GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 1.1.1.25,2.7.1.71,4.2.1.10,4.2.3.4 ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R02413,R03083,R03084 RC00002,RC00078,RC00206,RC00847,RC00848 ko00000,ko00001,ko00002,ko01000,ko03000 iAPECO1_1312.APECO1_1620,iECOK1_1307.ECOK1_0367,iECS88_1305.ECS88_0383,iUMN146_1321.UM146_15425,iUTI89_1310.UTI89_C0407,iYL1228.KPN_00332 Bacteria 1VA6Z@1239,3F7FE@33958,4HKD6@91061,COG0703@1,COG0703@2 NA|NA|NA F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate gnl|extdb|FAM1079-i1-1.1_000755 797515.HMPREF9103_00787 4.8e-141 507.3 Lactobacillaceae aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQRY@1239,3F4WM@33958,4HD4R@91061,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) gnl|extdb|FAM1079-i1-1.1_000756 797515.HMPREF9103_00786 3.8e-82 310.8 Lactobacillaceae thiW ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V6HH@1239,3F6M6@33958,4HHG6@91061,COG4732@1,COG4732@2 NA|NA|NA S Thiamine-precursor transporter protein (ThiW) gnl|extdb|FAM1079-i1-1.1_000757 797515.HMPREF9103_00785 1.1e-245 855.5 Lactobacillaceae fucP ko:K02429 ko00000,ko02000 2.A.1.7 Bacteria 1TQ1K@1239,3F3U4@33958,4HTTC@91061,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000758 797515.HMPREF9103_00784 2.1e-64 251.5 Lactobacillaceae rbsD GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009056,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016052,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0016887,GO:0017111,GO:0019303,GO:0019321,GO:0019323,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0042802,GO:0043211,GO:0043492,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:1901575 5.4.99.62 ko:K06726 ko02010,map02010 R08247 RC02247 ko00000,ko00001,ko01000 iAF1260.b3748,iBWG_1329.BWG_3439,iECDH10B_1368.ECDH10B_3936,iECDH1ME8569_1439.ECDH1ME8569_3636,iECH74115_1262.ECH74115_5184,iECSP_1301.ECSP_4798,iECs_1301.ECs4690,iETEC_1333.ETEC_4039,iEcDH1_1363.EcDH1_4219,iJO1366.b3748,iJR904.b3748,iY75_1357.Y75_RS18330 Bacteria 1VA2V@1239,3F6GA@33958,4HIFW@91061,COG1869@1,COG1869@2 NA|NA|NA G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose gnl|extdb|FAM1079-i1-1.1_000759 797515.HMPREF9103_00783 1.8e-184 651.7 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1VUK7@1239,3F4SV@33958,4HVQD@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family gnl|extdb|FAM1079-i1-1.1_000760 797515.HMPREF9103_00782 0.0 1211.1 Lactobacillaceae lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter gnl|extdb|FAM1079-i1-1.1_000762 797515.HMPREF9103_00780 0.0 1227.6 Lactobacillaceae XK27_11280 Bacteria 1TQFA@1239,2BW99@1,2Z7PD@2,3F4D7@33958,4HC1J@91061 NA|NA|NA S Psort location CytoplasmicMembrane, score gnl|extdb|FAM1079-i1-1.1_000763 797515.HMPREF9103_00779 8.9e-62 242.7 Lactobacillaceae Bacteria 1VWQW@1239,2E4BT@1,33YQ0@2,3FBRI@33958,4HWWB@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000764 525318.HMPREF0497_0466 6.1e-132 476.9 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase gnl|extdb|FAM1079-i1-1.1_000765 797515.HMPREF9103_00777 1.2e-103 382.5 Lactobacillaceae ko:K09155 ko00000 Bacteria 1TRD5@1239,3F45M@33958,4HAAW@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain gnl|extdb|FAM1079-i1-1.1_000766 797515.HMPREF9103_01976 0.0 2011.5 Lactobacillaceae carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase gnl|extdb|FAM1079-i1-1.1_000767 797515.HMPREF9103_01977 8.7e-209 732.6 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain gnl|extdb|FAM1079-i1-1.1_000768 797515.HMPREF9103_01978 1.6e-179 635.2 Lactobacillaceae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1TQ96@1239,3F4BQ@33958,4H9M6@91061,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family gnl|extdb|FAM1079-i1-1.1_000769 797515.HMPREF9103_01979 5.2e-237 826.6 Lactobacillaceae pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,3F3S3@33958,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily gnl|extdb|FAM1079-i1-1.1_000770 797515.HMPREF9103_01980 2.2e-96 358.2 Lactobacillaceae 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 1VXC7@1239,3F45R@33958,4HX58@91061,COG0494@1,COG0494@2 NA|NA|NA L Belongs to the Nudix hydrolase family gnl|extdb|FAM1079-i1-1.1_000771 797515.HMPREF9103_01981 3.8e-48 197.2 Lactobacillaceae sugE ko:K11741 ko00000,ko02000 2.A.7.1 Bacteria 1VEZX@1239,3F7D6@33958,4HKXB@91061,COG2076@1,COG2076@2 NA|NA|NA U Multidrug resistance protein gnl|extdb|FAM1079-i1-1.1_000772 797515.HMPREF9103_01982 5.6e-214 750.0 Lactobacillaceae serA 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V410@1239,3F4JJ@33958,4H9PH@91061,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_000773 797515.HMPREF9103_01983 5.2e-206 723.4 Lactobacillaceae serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP6Y@1239,3F4IU@33958,4HATT@91061,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine gnl|extdb|FAM1079-i1-1.1_000774 797515.HMPREF9103_01984 4.2e-115 420.6 Lactobacillaceae Bacteria 1V6ES@1239,3F5SD@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase gnl|extdb|FAM1079-i1-1.1_000775 797515.HMPREF9103_01985 7.6e-166 589.7 Lactobacillaceae menA 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TSZV@1239,3F3JM@33958,4HA68@91061,COG1575@1,COG1575@2 NA|NA|NA H 1,4-dihydroxy-2-naphthoate gnl|extdb|FAM1079-i1-1.1_000776 525318.HMPREF0497_0483 7.6e-113 413.3 Lactobacillaceae menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQEA@1239,3F3R2@33958,4HAR9@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) gnl|extdb|FAM1079-i1-1.1_000777 797515.HMPREF9103_01988 3.9e-63 247.3 Lactobacillaceae yjgF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009636,GO:0009987,GO:0016787,GO:0019239,GO:0019752,GO:0042221,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051082,GO:0071704,GO:1901564,GO:1901605 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 1V6HG@1239,3F7KB@33958,4HKEF@91061,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP gnl|extdb|FAM1079-i1-1.1_000780 797515.HMPREF9103_01991 5e-79 300.8 Bacteria ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM1079-i1-1.1_000782 387344.LVIS_0012 8.5e-22 110.9 Lactobacillaceae Bacteria 1U5DH@1239,2DKJ3@1,309NE@2,3F5MT@33958,4IF4V@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000783 797515.HMPREF9103_02007 1e-108 399.4 Lactobacillaceae Bacteria 1V3R8@1239,3F6RQ@33958,4HBEK@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000784 797515.HMPREF9103_02006 2.6e-201 708.0 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQG7@1239,3F40D@33958,4H9MK@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_000785 797515.HMPREF9103_02005 7.6e-132 476.5 Lactobacillaceae ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQKM@1239,3F3VV@33958,4HBUK@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM1079-i1-1.1_000787 797515.HMPREF9103_03075 3.6e-185 654.1 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_000788 797515.HMPREF9103_03076 2.3e-92 344.7 Lactobacillaceae ko:K07005 ko00000 Bacteria 1VB7Q@1239,3F6Z4@33958,4HSEE@91061,COG3467@1,COG3467@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase gnl|extdb|FAM1079-i1-1.1_000790 797515.HMPREF9103_03078 0.0 1124.4 Lactobacillaceae yknV ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_000792 525318.HMPREF0497_0493 1.1e-174 619.4 Lactobacillaceae Bacteria 1W0CD@1239,2FCGI@1,344JZ@2,3F4X9@33958,4HYAJ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000793 797515.HMPREF9103_03081 1.1e-86 325.9 Lactobacillaceae btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 1V3M3@1239,3F6A9@33958,4HH5Q@91061,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family gnl|extdb|FAM1079-i1-1.1_000794 797515.HMPREF9103_03082 0.0 1422.9 Lactobacillaceae ylbB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease gnl|extdb|FAM1079-i1-1.1_000795 797515.HMPREF9103_03084 3.8e-125 454.1 Lactobacillaceae macB ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,3F3YU@33958,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000797 797515.HMPREF9103_03085 6.1e-199 699.9 Lactobacillaceae Bacteria 1W017@1239,2FCGI@1,344JZ@2,3F3ZT@33958,4HY8J@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000798 797515.HMPREF9103_03087 1.5e-89 335.5 Lactobacillaceae ygfC Bacteria 1VXZV@1239,3FCEI@33958,4HXIZ@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator (TetR family) gnl|extdb|FAM1079-i1-1.1_000799 797515.HMPREF9103_03088 7.2e-184 649.8 Lactobacillaceae hrtB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TWFZ@1239,3F3K5@33958,4H9RQ@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease gnl|extdb|FAM1079-i1-1.1_000800 797515.HMPREF9103_03089 2.4e-119 434.9 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1TQP5@1239,3F4RP@33958,4HBXK@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000801 797515.HMPREF9103_03090 3.1e-203 714.1 Lactobacillaceae Bacteria 1TQ5U@1239,3F6DB@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase gnl|extdb|FAM1079-i1-1.1_000802 797515.HMPREF9103_03091 7e-264 916.0 Lactobacillaceae purB2 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMM@1239,3F583@33958,4HDVU@91061,COG0015@1,COG0015@2 NA|NA|NA F Adenylosuccinate lyase C-terminus gnl|extdb|FAM1079-i1-1.1_000803 797515.HMPREF9103_03092 1.6e-51 208.4 Lactobacillaceae gcsH2 ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1V6WV@1239,3F6YH@33958,4HIMA@91061,COG0509@1,COG0509@2 NA|NA|NA E Glycine cleavage H-protein gnl|extdb|FAM1079-i1-1.1_000804 797515.HMPREF9103_03093 1.3e-93 349.0 Lactobacillaceae ymdB Bacteria 1TPCU@1239,3F6GV@33958,4HIHC@91061,COG2110@1,COG2110@2 NA|NA|NA S Macro domain protein gnl|extdb|FAM1079-i1-1.1_000805 525318.HMPREF0497_0507 2.2e-125 455.3 Lactobacillaceae hipB GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K15773 ko00000,ko02048,ko03000 Bacteria 1VDMN@1239,3F5A3@33958,4HDVP@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix gnl|extdb|FAM1079-i1-1.1_000806 525318.HMPREF0497_0508 5.2e-100 370.5 Lactobacillaceae nreC ko:K02282,ko:K07696 ko02020,map02020 M00483 ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 Bacteria 1TQ1U@1239,3F4DN@33958,4HA4B@91061,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon gnl|extdb|FAM1079-i1-1.1_000807 525318.HMPREF0497_0509 1.3e-124 453.0 Lactobacillaceae comP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07680,ko:K07683 ko02020,ko02024,map02020,map02024 M00476,M00483 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQI3@1239,3F3XQ@33958,4HAUU@91061,COG4585@1,COG4585@2 NA|NA|NA F Sensor histidine kinase gnl|extdb|FAM1079-i1-1.1_000808 797515.HMPREF9103_03132 7e-38 163.3 Lactobacillaceae ydiI Bacteria 1V7G2@1239,3F7FT@33958,4HIIA@91061,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily gnl|extdb|FAM1079-i1-1.1_000809 797515.HMPREF9103_03133 3.2e-155 554.3 Lactobacillaceae menB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071890,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNU@1239,3F5HN@33958,4HAD0@91061,COG0447@1,COG0447@2 NA|NA|NA H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) gnl|extdb|FAM1079-i1-1.1_000810 797515.HMPREF9103_03134 2.1e-266 924.5 Lactobacillaceae menE 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPSX@1239,3F453@33958,4HACS@91061,COG0318@1,COG0318@2 NA|NA|NA H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily gnl|extdb|FAM1079-i1-1.1_000811 797515.HMPREF9103_03135 1.2e-255 888.6 Lactobacillaceae xylE ko:K02100 ko00000,ko02000 2.A.1.1.2 Bacteria 1TREV@1239,3F3ZS@33958,4HAN1@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000812 797515.HMPREF9103_03137 0.0 1124.8 Lactobacillaceae cadA Bacteria 1TQ07@1239,3F4JI@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase gnl|extdb|FAM1079-i1-1.1_000813 797515.HMPREF9103_03139 8e-165 586.3 Lactobacillaceae 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 R01708 RC00116 ko00000,ko00001,ko01000 Bacteria 1UYMV@1239,3F4I8@33958,4HE0W@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_000814 525318.HMPREF0497_0553 6.1e-224 783.5 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1VT8Q@1239,3F49N@33958,4HB84@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase gnl|extdb|FAM1079-i1-1.1_000815 797515.HMPREF9103_03142 0.0 1437.6 Lactobacillaceae ppk GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iJN746.PP_5217 Bacteria 1TNZM@1239,3F3PE@33958,4HA88@91061,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) gnl|extdb|FAM1079-i1-1.1_000816 797515.HMPREF9103_03143 1.1e-172 612.5 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase gnl|extdb|FAM1079-i1-1.1_000817 797515.HMPREF9103_03144 4.5e-110 404.1 Lactobacillaceae Bacteria 1U5TU@1239,2DKKZ@1,309W4@2,3F6HT@33958,4IFHT@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000818 797515.HMPREF9103_03145 4.3e-207 728.0 Bacilli pip1 ko:K01421 ko00000 Bacteria 1TQ15@1239,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein gnl|extdb|FAM1079-i1-1.1_000819 797515.HMPREF9103_03147 1.3e-267 929.1 Lactobacillaceae pip1 ko:K01421 ko00000 Bacteria 1TQ15@1239,3F3Y3@33958,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein gnl|extdb|FAM1079-i1-1.1_000820 797515.HMPREF9103_03149 2.5e-65 254.6 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6BR@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family gnl|extdb|FAM1079-i1-1.1_000821 797515.HMPREF9103_03150 1.6e-218 765.0 Lactobacillaceae arcT 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1TQPD@1239,3F3PZ@33958,4HE7P@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM1079-i1-1.1_000822 1071400.LBUCD034_2091 1.2e-58 232.3 Lactobacillaceae Bacteria 1VJIW@1239,3F707@33958,4HW5V@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain gnl|extdb|FAM1079-i1-1.1_000823 1071400.LBUCD034_2090 5.3e-90 337.0 Lactobacillaceae yetL GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K15973 ko00000,ko03000 Bacteria 1V6HZ@1239,3F7GC@33958,4HXEF@91061,COG1846@1,COG1846@2 NA|NA|NA K MarR family gnl|extdb|FAM1079-i1-1.1_000825 797515.HMPREF9103_03152 2.3e-165 588.2 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1VZMF@1239,3F5Z3@33958,4HY0D@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase gnl|extdb|FAM1079-i1-1.1_000826 797515.HMPREF9103_03153 2.6e-65 254.6 Lactobacillaceae Bacteria 1VYYP@1239,2CARX@1,34BQY@2,3F7EH@33958,4HYXX@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000738 797515.HMPREF9103_00807 1.6e-118 432.2 Lactobacillaceae Bacteria 1V26W@1239,3F3TU@33958,4HGMW@91061,COG1814@1,COG1814@2 NA|NA|NA S membrane gnl|extdb|FAM1079-i1-1.1_000761 797515.HMPREF9103_00781 3.7e-263 913.7 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_000786 525318.HMPREF0497_0488 6e-192 676.8 Lactobacillaceae patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM1079-i1-1.1_000789 797515.HMPREF9103_03077 1.7e-148 531.9 Lactobacillaceae Bacteria 1V7WE@1239,2B4EH@1,31X62@2,3F59Z@33958,4HJ8G@91061 NA|NA|NA S TraX protein gnl|extdb|FAM1079-i1-1.1_000791 797515.HMPREF9103_03079 4.4e-149 533.9 Lactobacillaceae Bacteria 1U6Q2@1239,29PYP@1,30AI2@2,3F8A6@33958,4IGH3@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000827 511437.Lbuc_0028 1.9e-109 402.1 Lactobacillaceae tnp2PF3 Bacteria 1VXWA@1239,3F6KZ@33958,4HXG3@91061,COG3293@1,COG3293@2 NA|NA|NA L manually curated gnl|extdb|FAM1079-i1-1.1_000829 797515.HMPREF9103_01735 4.9e-241 840.1 Lactobacillaceae dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1TPCT@1239,3F4MW@33958,4H9Y8@91061,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication gnl|extdb|FAM1079-i1-1.1_000830 797515.HMPREF9103_01736 2.7e-71 274.6 Lactobacillaceae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6QG@1239,3F68P@33958,4HIKJ@91061,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA gnl|extdb|FAM1079-i1-1.1_000832 797515.HMPREF9103_01915 2.1e-35 154.5 Lactobacillaceae rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 1V9XS@1239,3F7CY@33958,4HKCC@91061,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit gnl|extdb|FAM1079-i1-1.1_000833 797515.HMPREF9103_01916 4.2e-58 231.1 Lactobacillaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,3F66N@33958,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism gnl|extdb|FAM1079-i1-1.1_000834 797515.HMPREF9103_01917 2.7e-48 197.6 Lactobacillaceae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA18@1239,3F6ZY@33958,4HKHD@91061,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA gnl|extdb|FAM1079-i1-1.1_000836 334390.LAF_1568 2.2e-157 561.6 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 gnl|extdb|FAM1079-i1-1.1_000837 334390.LAF_1569 3.7e-108 397.5 Lactobacillaceae ko:K07483,ko:K07497 ko00000 Bacteria 1V4FD@1239,3FBFG@33958,4IQ19@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain gnl|extdb|FAM1079-i1-1.1_000839 797515.HMPREF9103_02800 1.1e-187 662.5 Lactobacillaceae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,3F3KU@33958,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage gnl|extdb|FAM1079-i1-1.1_000840 797515.HMPREF9103_02801 5.7e-80 303.5 Lactobacillaceae cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1TQ1N@1239,3F4I4@33958,4HATN@91061,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family gnl|extdb|FAM1079-i1-1.1_000841 797515.HMPREF9103_02802 6.2e-97 360.1 Lactobacillaceae pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iSB619.SA_RS06365 Bacteria 1V6PJ@1239,3F4BI@33958,4HCEX@91061,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family gnl|extdb|FAM1079-i1-1.1_000842 797515.HMPREF9103_02803 1.5e-114 419.5 Lactobacillaceae ymfM ko:K15539 ko00000 Bacteria 1V1N7@1239,3FC83@33958,4HKW3@91061,COG1426@1,COG1426@2 NA|NA|NA S Domain of unknown function (DUF4115) gnl|extdb|FAM1079-i1-1.1_000844 797515.HMPREF9103_02805 8.6e-216 756.1 Lactobacillaceae ymfF Bacteria 1TPN6@1239,3F3SA@33958,4H9P5@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 inactive domain protein gnl|extdb|FAM1079-i1-1.1_000845 797515.HMPREF9103_02806 4e-161 573.9 Lactobacillaceae aatB ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1UXYA@1239,3FC5A@33958,4H9NJ@91061,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins gnl|extdb|FAM1079-i1-1.1_000846 797515.HMPREF9103_02807 2.8e-114 417.9 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1UYAZ@1239,3F4GP@33958,4HE6M@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter gnl|extdb|FAM1079-i1-1.1_000847 797515.HMPREF9103_02808 2.1e-85 322.0 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1V280@1239,3FC56@33958,4HDST@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_000848 525318.HMPREF0497_2225 1.7e-140 505.4 Lactobacillaceae minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03609 ko00000,ko03036,ko04812 Bacteria 1TP6P@1239,3F3U8@33958,4HB2F@91061,COG2894@1,COG2894@2 NA|NA|NA D Belongs to the ParA family gnl|extdb|FAM1079-i1-1.1_000849 797515.HMPREF9103_02811 3.5e-107 394.4 Lactobacillaceae minC GO:0000910,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0032506,GO:0036214,GO:0051179,GO:0051301,GO:0061640 ko:K03610 ko00000,ko03036,ko04812 Bacteria 1VAPC@1239,3F61V@33958,4HBTI@91061,COG0850@1,COG0850@2 NA|NA|NA D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization gnl|extdb|FAM1079-i1-1.1_000850 797515.HMPREF9103_02812 1.1e-89 335.9 Lactobacillaceae mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1VEV7@1239,3F6PG@33958,4HPAC@91061,COG2891@1,COG2891@2 NA|NA|NA M rod shape-determining protein MreD gnl|extdb|FAM1079-i1-1.1_000851 797515.HMPREF9103_02813 7.8e-152 543.1 Lactobacillaceae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1TR1V@1239,3F3MC@33958,4HB0K@91061,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape gnl|extdb|FAM1079-i1-1.1_000853 797515.HMPREF9103_02815 5.1e-251 873.2 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F498@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family gnl|extdb|FAM1079-i1-1.1_000854 525318.HMPREF0497_2219 0.0 1709.5 Lactobacillaceae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1TPN4@1239,3F3RB@33958,4HB85@91061,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner gnl|extdb|FAM1079-i1-1.1_000855 797515.HMPREF9103_02818 1.3e-90 339.0 Lactobacillaceae tpx 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 1V474@1239,3F5VY@33958,4HFMW@91061,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides gnl|extdb|FAM1079-i1-1.1_000856 797515.HMPREF9103_02819 7.6e-230 802.7 Lactobacillaceae thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07461 ko00000,ko00001,ko01000,ko03016 iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 Bacteria 1TPNW@1239,3F3N0@33958,4HAV9@91061,COG0301@1,COG0301@2 NA|NA|NA H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS gnl|extdb|FAM1079-i1-1.1_000857 797515.HMPREF9103_02820 1.1e-214 752.3 Lactobacillaceae iscS2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F4CD@33958,4HAEE@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V gnl|extdb|FAM1079-i1-1.1_000858 797515.HMPREF9103_02821 0.0 1107.0 Lactobacillaceae ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 ko:K06286,ko:K07158 ko00000,ko03036 Bacteria 1TQR7@1239,3F47K@33958,4HA15@91061,COG4477@1,COG4477@2 NA|NA|NA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization gnl|extdb|FAM1079-i1-1.1_000859 797515.HMPREF9103_02822 1.3e-78 298.9 Lactobacillaceae ytsP 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 1V6GQ@1239,3F6NT@33958,4HH7X@91061,COG1956@1,COG1956@2 NA|NA|NA T GAF domain-containing protein gnl|extdb|FAM1079-i1-1.1_000860 797515.HMPREF9103_02823 9.8e-109 399.4 Lactobacillaceae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TR0J@1239,3F3P0@33958,4HAC9@91061,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit gnl|extdb|FAM1079-i1-1.1_000861 797515.HMPREF9103_02824 1.8e-234 818.1 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3WF@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA gnl|extdb|FAM1079-i1-1.1_000862 797515.HMPREF9103_02825 1.8e-28 131.7 Lactobacillaceae Bacteria 1U6X1@1239,2BGK5@1,32AIK@2,3F8N8@33958,4IGR8@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000863 797515.HMPREF9103_02826 1.8e-81 308.5 Lactobacillaceae usp6 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1V3NY@1239,3F68T@33958,4HIP3@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein gnl|extdb|FAM1079-i1-1.1_000864 797515.HMPREF9103_02827 3.7e-152 544.3 Lactobacillaceae Bacteria 1VMYH@1239,3F5QH@33958,4ISF0@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_000865 797515.HMPREF9103_02828 9.6e-92 342.8 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UV5N@1239,3F6CF@33958,4I3AQ@91061,COG2818@1,COG2818@2 NA|NA|NA L Methyladenine glycosylase gnl|extdb|FAM1079-i1-1.1_000866 797515.HMPREF9103_02829 6.4e-197 693.7 Lactobacillaceae glpQ3 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UG1C@1239,3F57C@33958,4HCPQ@91061,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family gnl|extdb|FAM1079-i1-1.1_000867 797515.HMPREF9103_02831 3.7e-210 737.3 Lactobacillaceae ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP2Y@1239,3F41Z@33958,4H9KB@91061,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family gnl|extdb|FAM1079-i1-1.1_000868 797515.HMPREF9103_02832 6.1e-132 476.9 Lactobacillaceae Bacteria 1W561@1239,28V9H@1,2ZHCF@2,3F5C3@33958,4I11A@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000869 525318.HMPREF0497_2204 1.7e-146 525.4 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TS5Y@1239,3F4BF@33958,4HBUA@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000870 797515.HMPREF9103_02835 7.8e-61 239.6 Lactobacillaceae gntR1 ko:K07979 ko00000,ko03000 Bacteria 1VAC6@1239,3F721@33958,4HKVW@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family gnl|extdb|FAM1079-i1-1.1_000872 797515.HMPREF9103_02838 9.8e-135 486.1 Lactobacillaceae cysA ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TNZG@1239,3F3MG@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_000873 797515.HMPREF9103_02839 5.2e-148 530.4 Lactobacillaceae f42a Bacteria 1TRN5@1239,3F4ES@33958,4HA6G@91061,COG0330@1,COG0330@2 NA|NA|NA O Band 7 protein gnl|extdb|FAM1079-i1-1.1_000874 1423780.LOT_0550 7.2e-139 500.0 Lactobacillaceae metQ ko:K02072,ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3FC6J@33958,4HBK0@91061,COG1464@1,COG1464@2 NA|NA|NA M Belongs to the nlpA lipoprotein family gnl|extdb|FAM1079-i1-1.1_000875 797515.HMPREF9103_02842 1.8e-74 285.8 Lactobacillaceae metI GO:0000101,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0042940,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072348 ko:K02069,ko:K02072 ko02010,map02010 M00211,M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24,9.B.25.1 Bacteria 1TR59@1239,3FC5J@33958,4H9NA@91061,COG2011@1,COG2011@2 NA|NA|NA U ABC transporter permease gnl|extdb|FAM1079-i1-1.1_000876 797515.HMPREF9103_02843 7e-184 649.8 Lactobacillaceae metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 iYO844.BSU32750 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_000877 797515.HMPREF9103_02844 1.9e-46 191.4 Lactobacillaceae ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1V6WV@1239,3F7WB@33958,4HIMA@91061,COG0509@1,COG0509@2 NA|NA|NA E glycine cleavage gnl|extdb|FAM1079-i1-1.1_000878 797515.HMPREF9103_02845 6.8e-223 779.6 Lactobacillaceae rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,3F4J4@33958,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family gnl|extdb|FAM1079-i1-1.1_000879 797515.HMPREF9103_02846 1.4e-33 148.3 Lactobacillaceae Bacteria 1U6E1@1239,2BQ47@1,30AA9@2,3F7PI@33958,4IG5V@91061 NA|NA|NA S Protein of unknown function (DUF2969) gnl|extdb|FAM1079-i1-1.1_000880 797515.HMPREF9103_02847 1.9e-48 198.0 Lactobacillaceae yidD ko:K08998 ko00000 Bacteria 1VEIG@1239,3F7H1@33958,4HPA3@91061,COG0759@1,COG0759@2 NA|NA|NA S Could be involved in insertion of integral membrane proteins into the membrane gnl|extdb|FAM1079-i1-1.1_000881 797515.HMPREF9103_02848 3.3e-178 630.9 Lactobacillaceae mbl ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F463@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D Cell shape determining protein MreB Mrl gnl|extdb|FAM1079-i1-1.1_000882 797515.HMPREF9103_02849 9.4e-242 842.4 Lactobacillaceae murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine gnl|extdb|FAM1079-i1-1.1_000883 797515.HMPREF9103_02850 2.1e-32 144.4 Lactobacillaceae ywzB Bacteria 1VK5C@1239,3F88D@33958,4HR8D@91061,COG4836@1,COG4836@2 NA|NA|NA S Protein of unknown function (DUF1146) gnl|extdb|FAM1079-i1-1.1_000884 797515.HMPREF9103_02851 1.4e-58 232.3 Lactobacillaceae atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1VA89@1239,3F6I6@33958,4HKHS@91061,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane gnl|extdb|FAM1079-i1-1.1_000885 797515.HMPREF9103_02852 8.4e-260 902.5 Lactobacillaceae atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10965 Bacteria 1TPGF@1239,3F3TF@33958,4HAT6@91061,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits gnl|extdb|FAM1079-i1-1.1_000886 797515.HMPREF9103_02853 1.6e-163 582.0 Lactobacillaceae atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820 Bacteria 1TPBX@1239,3F40E@33958,4HB0E@91061,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex gnl|extdb|FAM1079-i1-1.1_000887 797515.HMPREF9103_02854 1.3e-293 1015.0 Lactobacillaceae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1TNZ8@1239,3F3R4@33958,4HAMZ@91061,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit gnl|extdb|FAM1079-i1-1.1_000888 797515.HMPREF9103_02855 2.4e-90 338.2 Lactobacillaceae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VAG3@1239,3FC80@33958,4HKFW@91061,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation gnl|extdb|FAM1079-i1-1.1_000889 797515.HMPREF9103_02856 2.7e-51 208.4 Lactobacillaceae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01170,iYO844.BSU36850 Bacteria 1VB85@1239,3F5M8@33958,4HM64@91061,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) gnl|extdb|FAM1079-i1-1.1_000890 1423743.JCM14108_156 2.1e-26 124.4 Lactobacillaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VEHP@1239,3F82A@33958,4HNKQ@91061,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation gnl|extdb|FAM1079-i1-1.1_000891 797515.HMPREF9103_02858 1.6e-126 458.8 Lactobacillaceae atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1TQIT@1239,3F3RE@33958,4H9NV@91061,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane gnl|extdb|FAM1079-i1-1.1_000892 797515.HMPREF9103_02859 1.6e-114 418.7 Lactobacillaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,3F4M0@33958,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate gnl|extdb|FAM1079-i1-1.1_000893 797515.HMPREF9103_02860 1.3e-224 785.4 Lactobacillaceae glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVM@1239,3F4C1@33958,4HA5K@91061,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism gnl|extdb|FAM1079-i1-1.1_000894 797515.HMPREF9103_02861 4.1e-192 677.2 Lactobacillaceae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP1I@1239,3F3T1@33958,4HA7W@91061,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine gnl|extdb|FAM1079-i1-1.1_000895 797515.HMPREF9103_02862 2.5e-150 538.1 Lactobacillaceae prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1TSMA@1239,3F460@33958,4HC6W@91061,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif gnl|extdb|FAM1079-i1-1.1_000896 797515.HMPREF9103_02863 4.6e-186 657.1 Lactobacillaceae prfA ko:K02835 ko00000,ko03012 Bacteria 1TQ7V@1239,3F3Q0@33958,4H9MB@91061,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA gnl|extdb|FAM1079-i1-1.1_000897 797515.HMPREF9103_02864 3.8e-113 414.1 Lactobacillaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 1TRVM@1239,3F4UE@33958,4HA4A@91061,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase gnl|extdb|FAM1079-i1-1.1_000898 797515.HMPREF9103_02865 7.1e-261 906.0 Lactobacillaceae murD 3.4.21.10,6.3.2.13,6.3.2.9 ko:K01317,ko:K01925,ko:K01928,ko:K01932 ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100 R02783,R02788 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011,ko04131 Bacteria 1UHPI@1239,3F3TN@33958,4HVP0@91061,COG0771@1,COG0771@2 NA|NA|NA M Mur ligase, middle domain gnl|extdb|FAM1079-i1-1.1_000899 797515.HMPREF9103_02866 2.7e-134 484.6 Lactobacillaceae cobQ ko:K07009 ko00000 Bacteria 1U7I9@1239,3F4CH@33958,4HD1P@91061,COG3442@1,COG3442@2 NA|NA|NA S glutamine amidotransferase gnl|extdb|FAM1079-i1-1.1_000900 525318.HMPREF0497_2173 2.2e-150 538.5 Lactobacillaceae ampC Bacteria 1U828@1239,3FBDZ@33958,4HA0Q@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM1079-i1-1.1_000901 797515.HMPREF9103_02870 3.2e-58 230.7 Lactobacillaceae Bacteria 1W08C@1239,2FI40@1,349WT@2,3F7QX@33958,4HYGC@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000902 797515.HMPREF9103_02871 9.9e-98 362.8 Lactobacillaceae Bacteria 1U649@1239,2C33C@1,30A2Y@2,3F70H@33958,4IFTY@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000903 797515.HMPREF9103_02872 3.2e-256 890.6 Lactobacillaceae Bacteria 1U57W@1239,29HXA@1,300RR@2,3F51X@33958,4IEZ4@91061 NA|NA|NA S Zinc-dependent metalloprotease gnl|extdb|FAM1079-i1-1.1_000908 60520.HR47_10450 2.6e-133 482.3 Lactobacillaceae Bacteria 1TQNX@1239,3F4EZ@33958,4HCHZ@91061,COG5545@1,COG5545@2 NA|NA|NA S Virulence-associated protein E gnl|extdb|FAM1079-i1-1.1_000909 511437.Lbuc_0031 1.6e-95 355.9 Firmicutes Bacteria 1UJSF@1239,COG3598@1,COG3598@2 NA|NA|NA L Bifunctional DNA primase/polymerase, N-terminal gnl|extdb|FAM1079-i1-1.1_000911 511437.Lbuc_0023 3.7e-29 134.0 Lactobacillaceae Bacteria 1U72M@1239,2BT58@1,32NA3@2,3F8WB@33958,4IGX6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000912 1114972.AUAW01000005_gene264 1.9e-11 74.7 Bacilli ko:K07727 ko00000,ko03000 Bacteria 1VJ53@1239,2ETUS@1,33MC1@2,4HRM0@91061 NA|NA|NA K Cro/C1-type HTH DNA-binding domain gnl|extdb|FAM1079-i1-1.1_000913 416870.llmg_2262 1.3e-10 73.6 Bacteria ko:K07727 ko00000,ko03000 Bacteria COG3655@1,COG3655@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_000914 511437.Lbuc_0020 6.9e-172 610.1 Lactobacillaceae sip Bacteria 1TTJI@1239,3F4IB@33958,4HDG6@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family gnl|extdb|FAM1079-i1-1.1_000917 525318.HMPREF0497_2162 3.9e-120 437.6 Lactobacillaceae Bacteria 1TQUQ@1239,3F3QZ@33958,4HAXP@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator gnl|extdb|FAM1079-i1-1.1_000918 797515.HMPREF9103_02881 4.7e-131 473.8 Lactobacillaceae Bacteria 1UD1Q@1239,3F4DU@33958,4IPI5@91061,COG4990@1,COG4990@2 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000921 1423734.JCM14202_1419 3.2e-33 149.4 Lactobacillaceae Bacteria 1V3SH@1239,3F6ZF@33958,4HNR1@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 gnl|extdb|FAM1079-i1-1.1_000923 349123.Lreu23DRAFT_3295 1.5e-133 483.0 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein gnl|extdb|FAM1079-i1-1.1_000924 1071400.LBUCD034_0974 2.1e-11 74.7 Lactobacillaceae Bacteria 1U7Y7@1239,2BNJB@1,32H82@2,3FABC@33958,4IHVJ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000925 1071400.LBUCD034_0973 6e-16 90.1 Lactobacillaceae Bacteria 1VEAE@1239,2E02M@1,32VRK@2,3F9Z6@33958,4HKYK@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000926 525318.HMPREF0497_1823 6.8e-55 219.9 Lactobacillaceae pdxH ko:K07006 ko00000 Bacteria 1VW4G@1239,3F6IW@33958,4HW37@91061,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase gnl|extdb|FAM1079-i1-1.1_000831 797515.HMPREF9103_01737 0.0 1247.6 Lactobacillaceae yybT Bacteria 1TPGP@1239,3F3TY@33958,4HBVH@91061,COG3887@1,COG3887@2 NA|NA|NA T signaling protein consisting of a modified GGDEF domain and a DHH domain gnl|extdb|FAM1079-i1-1.1_000838 797515.HMPREF9103_02799 8.7e-234 816.2 Lactobacillaceae rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,3F3WX@33958,4HC9J@91061,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay gnl|extdb|FAM1079-i1-1.1_000843 797515.HMPREF9103_02804 7.8e-241 839.3 Lactobacillaceae ymfH ko:K07263 ko00000,ko01000,ko01002 Bacteria 1TP5I@1239,3F4MU@33958,4H9YG@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 gnl|extdb|FAM1079-i1-1.1_000852 797515.HMPREF9103_02814 2.7e-156 558.1 Lactobacillaceae mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F3ZV@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D cell shape determining protein MreB gnl|extdb|FAM1079-i1-1.1_000871 1423743.JCM14108_132 1.5e-218 765.8 Lactobacillaceae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR2D@1239,3FBRY@33958,4H9SH@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family gnl|extdb|FAM1079-i1-1.1_000919 797515.HMPREF9103_02882 3.4e-146 524.2 Lactobacillaceae Bacteria 1TSZZ@1239,3FC8B@33958,4HHKJ@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase gnl|extdb|FAM1079-i1-1.1_000928 797515.HMPREF9103_00604 5.3e-43 179.9 Lactobacillaceae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,3F7DV@33958,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome gnl|extdb|FAM1079-i1-1.1_000929 797515.HMPREF9103_00605 3e-35 154.1 Lactobacillaceae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGX@1239,3F7D8@33958,4HNJS@91061,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA gnl|extdb|FAM1079-i1-1.1_000930 797515.HMPREF9103_00606 1.3e-185 655.6 Lactobacillaceae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRM0@1239,3F3TP@33958,4HBB4@91061,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit gnl|extdb|FAM1079-i1-1.1_000931 797515.HMPREF9103_00607 0.0 1430.2 Lactobacillaceae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1TS9U@1239,3F3VT@33958,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein ComEC gnl|extdb|FAM1079-i1-1.1_000932 797515.HMPREF9103_00608 4.8e-87 327.0 Lactobacillaceae comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1V3PU@1239,3F6BF@33958,4HCDG@91061,COG2131@1,COG2131@2 NA|NA|NA F ComE operon protein 2 gnl|extdb|FAM1079-i1-1.1_000933 797515.HMPREF9103_00609 1.9e-77 295.8 Lactobacillaceae comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1VA3W@1239,3F7NP@33958,4HKJ1@91061,COG1555@1,COG1555@2 NA|NA|NA L Competence protein ComEA gnl|extdb|FAM1079-i1-1.1_000934 797515.HMPREF9103_00334 7.3e-197 693.0 Lactobacillaceae ylbL ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 1TRUF@1239,3F4KY@33958,4HBAY@91061,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family gnl|extdb|FAM1079-i1-1.1_000935 797515.HMPREF9103_00335 1.1e-78 299.3 Lactobacillaceae coaD 2.7.7.3,3.6.1.55 ko:K00954,ko:K03574 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3MR@1239,3F6YS@33958,4HH47@91061,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate gnl|extdb|FAM1079-i1-1.1_000936 797515.HMPREF9103_00336 1.5e-100 372.1 Lactobacillaceae rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JF@1239,3F505@33958,4HGXT@91061,COG0742@1,COG0742@2 NA|NA|NA L RNA methyltransferase, RsmD family gnl|extdb|FAM1079-i1-1.1_000937 797515.HMPREF9103_00337 7.9e-45 186.0 Bacteria ylbG Bacteria COG4471@1,COG4471@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2129) gnl|extdb|FAM1079-i1-1.1_000938 797515.HMPREF9103_00338 6.1e-216 756.5 Lactobacillaceae ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1TPT7@1239,3F4IK@33958,4HAEV@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family gnl|extdb|FAM1079-i1-1.1_000939 1423743.JCM14108_631 0.0 1157.5 Lactobacillaceae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1TQ5Y@1239,3F3UK@33958,4HAQ6@91061,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA gnl|extdb|FAM1079-i1-1.1_000940 797515.HMPREF9103_00340 2.9e-142 511.1 Lactobacillaceae suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4E@1239,3F5BB@33958,4HB92@91061,COG0483@1,COG0483@2 NA|NA|NA G Belongs to the inositol monophosphatase superfamily gnl|extdb|FAM1079-i1-1.1_000941 797515.HMPREF9103_00341 4.2e-46 190.3 Lactobacillaceae yktA ko:K16509 ko00000 Bacteria 1VEK8@1239,3F80A@33958,4HNKR@91061,COG4476@1,COG4476@2 NA|NA|NA S Belongs to the UPF0223 family gnl|extdb|FAM1079-i1-1.1_000942 1423743.JCM14108_634 2.7e-250 870.9 Lactobacillaceae lpdA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 Bacteria 1TP1W@1239,3F426@33958,4HB3K@91061,COG1249@1,COG1249@2 NA|NA|NA C Dehydrogenase gnl|extdb|FAM1079-i1-1.1_000943 797515.HMPREF9103_00345 1.2e-212 745.7 Lactobacillaceae pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TR5N@1239,3F3RR@33958,4HA7A@91061,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex gnl|extdb|FAM1079-i1-1.1_000944 797515.HMPREF9103_00346 4.8e-182 643.7 Lactobacillaceae pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2496c,iYO844.BSU14590 Bacteria 1TP3J@1239,3F4RV@33958,4HA4H@91061,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, C-terminal domain protein gnl|extdb|FAM1079-i1-1.1_000945 797515.HMPREF9103_00347 1.9e-211 741.5 Lactobacillaceae pdhA 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TQDG@1239,3F3JK@33958,4H9PQ@91061,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component gnl|extdb|FAM1079-i1-1.1_000946 797515.HMPREF9103_00348 9.7e-103 379.4 Lactobacillaceae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V70B@1239,3F3YH@33958,4HH0G@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions gnl|extdb|FAM1079-i1-1.1_000947 797515.HMPREF9103_00349 6.2e-82 310.1 Lactobacillaceae Bacteria 1VQPI@1239,2C389@1,2ZQCN@2,3F79N@33958,4I0G9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000948 797515.HMPREF9103_00350 1.1e-33 148.7 Lactobacillaceae ykzG Bacteria 1VEI7@1239,3F807@33958,4HNSK@91061,COG5503@1,COG5503@2 NA|NA|NA S Belongs to the UPF0356 family gnl|extdb|FAM1079-i1-1.1_000949 797515.HMPREF9103_00351 0.0 1120.5 Lactobacillaceae rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3TT@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay gnl|extdb|FAM1079-i1-1.1_000950 797515.HMPREF9103_00352 2.7e-182 644.4 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V7DZ@1239,3F5GQ@33958,4HBUD@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain gnl|extdb|FAM1079-i1-1.1_000951 797515.HMPREF9103_00353 9.7e-180 636.0 Lactobacillaceae draG 3.2.2.24 ko:K05521 ko00000,ko01000 Bacteria 1TQXG@1239,3F509@33958,4HE5F@91061,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase gnl|extdb|FAM1079-i1-1.1_000952 797515.HMPREF9103_00354 4.9e-31 139.8 Lactobacillaceae Bacteria 1U6J4@1239,29PG6@1,30AEB@2,3F80Q@33958,4IGBN@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000953 797515.HMPREF9103_00355 4.8e-160 570.5 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway gnl|extdb|FAM1079-i1-1.1_000956 797515.HMPREF9103_00359 5.1e-165 587.0 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3V8@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) gnl|extdb|FAM1079-i1-1.1_000957 797515.HMPREF9103_00360 0.0 1617.1 Lactobacillaceae recD2 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,3F44X@33958,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity gnl|extdb|FAM1079-i1-1.1_000958 797515.HMPREF9103_00361 2.4e-133 481.5 Lactobacillaceae Bacteria 1VFGR@1239,3F4MD@33958,4IBSH@91061,COG0457@1,COG0457@2 NA|NA|NA S Repeat protein gnl|extdb|FAM1079-i1-1.1_000959 797515.HMPREF9103_00362 9.5e-118 429.5 Lactobacillaceae pspA 3.1.3.3 ko:K22305 ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130 R00582 RC00017 ko00000,ko00001,ko01000 Bacteria 1V6ES@1239,3F3U3@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase gnl|extdb|FAM1079-i1-1.1_000960 797515.HMPREF9103_00363 4.8e-160 570.5 Lactobacillaceae ywkB ko:K07088 ko00000 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein gnl|extdb|FAM1079-i1-1.1_000961 797515.HMPREF9103_00364 4.4e-224 783.5 Lactobacillaceae mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPIZ@1239,3F4N5@33958,4HBJ6@91061,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 gnl|extdb|FAM1079-i1-1.1_000962 797515.HMPREF9103_00365 2.1e-199 701.4 Lactobacillaceae hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPUV@1239,3F466@33958,4HA1H@91061,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily gnl|extdb|FAM1079-i1-1.1_000963 797515.HMPREF9103_00366 7e-53 213.0 Lactobacillaceae hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS14110,iYO844.BSU34860 Bacteria 1VB6S@1239,3F7V5@33958,4HKDY@91061,COG0140@1,COG0140@2 NA|NA|NA E phosphoribosyl-ATP diphosphatase activity gnl|extdb|FAM1079-i1-1.1_000965 797515.HMPREF9103_00368 8.9e-136 489.6 Lactobacillaceae hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 ko:K01663,ko:K02500,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04558 RC00002,RC00010,RC01055,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481 Bacteria 1TP0W@1239,3F3XV@33958,4HAAM@91061,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit gnl|extdb|FAM1079-i1-1.1_000966 525318.HMPREF0497_1322 1.5e-108 399.1 Lactobacillaceae hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 1V1IR@1239,3F5YT@33958,4HACP@91061,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase gnl|extdb|FAM1079-i1-1.1_000967 797515.HMPREF9103_00370 1.8e-110 405.2 Lactobacillaceae hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQT0@1239,3FBCG@33958,4HHSP@91061,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR gnl|extdb|FAM1079-i1-1.1_000968 797515.HMPREF9103_00371 3.1e-104 384.4 Lactobacillaceae hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 1TRH7@1239,3F4TQ@33958,4HCFG@91061,COG0131@1,COG0131@2 NA|NA|NA E imidazoleglycerol-phosphate dehydratase gnl|extdb|FAM1079-i1-1.1_000969 797515.HMPREF9103_00372 1.4e-116 425.6 Lactobacillaceae hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSVZ@1239,3F4WT@33958,4H9MH@91061,COG0040@1,COG0040@2 NA|NA|NA F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity gnl|extdb|FAM1079-i1-1.1_000970 797515.HMPREF9103_00373 3.4e-216 757.3 Lactobacillaceae hisZ 2.4.2.17,6.1.1.21 ko:K00765,ko:K01892,ko:K02502 ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230 M00026,M00359,M00360 R01071,R03655 RC00055,RC00523,RC02819,RC03200 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPZZ@1239,3F4W1@33958,4HBBA@91061,COG3705@1,COG3705@2 NA|NA|NA E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine gnl|extdb|FAM1079-i1-1.1_000971 797515.HMPREF9103_00375 7.2e-163 579.7 Lactobacillaceae hisK 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQQX@1239,3F4WG@33958,4H9P1@91061,COG1387@1,COG1387@2 NA|NA|NA E Histidinol phosphate phosphatase, HisJ gnl|extdb|FAM1079-i1-1.1_000972 797515.HMPREF9103_00376 3e-198 697.6 Lactobacillaceae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,3F4BD@33958,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase gnl|extdb|FAM1079-i1-1.1_000973 797515.HMPREF9103_00377 1.3e-198 698.7 Lactobacillaceae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,3F4BD@33958,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase gnl|extdb|FAM1079-i1-1.1_000974 797515.HMPREF9103_00378 1.5e-58 231.9 Lactobacillaceae XK27_04120 Bacteria 1VDSF@1239,2DHWG@1,32U9W@2,3F7E3@33958,4HP9N@91061 NA|NA|NA S Putative amino acid metabolism gnl|extdb|FAM1079-i1-1.1_000975 797515.HMPREF9103_00379 3.2e-217 760.8 Lactobacillaceae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F3RF@33958,4HA6H@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V gnl|extdb|FAM1079-i1-1.1_000976 797515.HMPREF9103_00380 2.7e-123 448.0 Lactobacillaceae mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7WK@1239,3F4HE@33958,4HB8K@91061,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively gnl|extdb|FAM1079-i1-1.1_000977 797515.HMPREF9103_00381 3.6e-45 187.2 Lactobacillaceae Bacteria 1U6G4@1239,2A67P@1,30V09@2,3F7U9@33958,4IG86@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_000978 797515.HMPREF9103_00382 7.6e-97 359.8 Lactobacillaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,3F53J@33958,4HII9@91061,COG0494@1,COG0494@2 NA|NA|NA L ADP-ribose pyrophosphatase gnl|extdb|FAM1079-i1-1.1_000979 797515.HMPREF9103_00383 4.2e-32 143.3 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1U6RM@1239,3F8DE@33958,4IGJ1@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold-Shock Protein gnl|extdb|FAM1079-i1-1.1_000980 797515.HMPREF9103_00384 0.0 1911.3 Lactobacillaceae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1TPS7@1239,3F3X4@33958,4HAWB@91061,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) gnl|extdb|FAM1079-i1-1.1_000981 797515.HMPREF9103_00385 2.6e-70 271.9 Lactobacillaceae divIVA ko:K04074 ko00000,ko03036 Bacteria 1V27M@1239,3F4IN@33958,4HG80@91061,COG3599@1,COG3599@2 NA|NA|NA D DivIVA domain protein gnl|extdb|FAM1079-i1-1.1_000982 797515.HMPREF9103_00386 2.5e-136 491.5 Lactobacillaceae ylmH ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1U5V2@1239,3F48W@33958,4HD3F@91061,COG2302@1,COG2302@2 NA|NA|NA S S4 domain protein gnl|extdb|FAM1079-i1-1.1_000984 797515.HMPREF9103_00388 2e-58 231.5 Lactobacillaceae sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 1VER3@1239,3F7MQ@33958,4HKIC@91061,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA gnl|extdb|FAM1079-i1-1.1_000985 797515.HMPREF9103_00389 1.5e-226 792.0 Lactobacillaceae ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1TP6W@1239,3F4V1@33958,4H9WZ@91061,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity gnl|extdb|FAM1079-i1-1.1_000986 797515.HMPREF9103_00390 6.6e-243 846.3 Lactobacillaceae ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TP1Z@1239,3F413@33958,4H9NF@91061,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring gnl|extdb|FAM1079-i1-1.1_000987 797515.HMPREF9103_00391 1.3e-151 542.3 Lactobacillaceae divIB ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1V6V5@1239,3F406@33958,4HDFD@91061,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex gnl|extdb|FAM1079-i1-1.1_000988 797515.HMPREF9103_00392 1.1e-203 715.7 Lactobacillaceae murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1TQFT@1239,3F4FW@33958,4HBAQ@91061,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) gnl|extdb|FAM1079-i1-1.1_000989 797515.HMPREF9103_00393 9.2e-256 889.0 Lactobacillaceae murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQ3P@1239,3F49W@33958,4HA5P@91061,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) gnl|extdb|FAM1079-i1-1.1_000990 797515.HMPREF9103_00394 2.5e-175 621.3 Lactobacillaceae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1TP8W@1239,3F3YP@33958,4H9TP@91061,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gnl|extdb|FAM1079-i1-1.1_000991 525318.HMPREF0497_1347 0.0 1175.2 Lactobacillaceae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1TP93@1239,3F47N@33958,4H9VQ@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein gnl|extdb|FAM1079-i1-1.1_000992 797515.HMPREF9103_00397 1e-55 222.6 Lactobacillaceae ftsL Bacteria 1VCE5@1239,3F6KG@33958,4HM4W@91061,COG4839@1,COG4839@2 NA|NA|NA D Cell division protein FtsL gnl|extdb|FAM1079-i1-1.1_000993 797515.HMPREF9103_00398 8.1e-179 632.9 Lactobacillaceae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1TNZV@1239,3F3MF@33958,4H9U2@91061,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA gnl|extdb|FAM1079-i1-1.1_000994 797515.HMPREF9103_00399 2e-76 291.6 Lactobacillaceae mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1V3JD@1239,3F6K3@33958,4HH23@91061,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family gnl|extdb|FAM1079-i1-1.1_000995 797515.HMPREF9103_00402 2.8e-61 241.1 Lactobacillaceae Bacteria 1U69J@1239,2DKP8@1,30A6M@2,3F7DD@33958,4IG0Q@91061 NA|NA|NA S Protein of unknown function (DUF3397) gnl|extdb|FAM1079-i1-1.1_000996 797515.HMPREF9103_00401 2.1e-19 100.9 Lactobacillaceae Bacteria 1U7W0@1239,2BN14@1,32GM9@2,3FA8T@33958,4IHTE@91061 NA|NA|NA S Protein of unknown function (DUF4044) gnl|extdb|FAM1079-i1-1.1_000997 797515.HMPREF9103_00403 0.0 1417.1 Lactobacillaceae ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F3JZ@33958,4H9WA@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family gnl|extdb|FAM1079-i1-1.1_000998 797515.HMPREF9103_00404 5e-90 337.0 Lactobacillaceae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1V3GW@1239,3F42Y@33958,4HFNY@91061,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily gnl|extdb|FAM1079-i1-1.1_000999 797515.HMPREF9103_00405 5.2e-161 573.5 Lactobacillaceae rrmA 2.1.1.187 ko:K00563,ko:K10947 R07233 RC00003 ko00000,ko01000,ko03000,ko03009 Bacteria 1V1WE@1239,3F4U3@33958,4HGQ9@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase gnl|extdb|FAM1079-i1-1.1_001000 797515.HMPREF9103_00406 3.7e-173 614.0 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F4AU@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA G Responsible for synthesis of pseudouridine from uracil gnl|extdb|FAM1079-i1-1.1_001001 797515.HMPREF9103_00407 6.2e-151 540.0 Lactobacillaceae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1TRB3@1239,3F45D@33958,4HB08@91061,COG0061@1,COG0061@2 NA|NA|NA F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP gnl|extdb|FAM1079-i1-1.1_001002 797515.HMPREF9103_00408 3.6e-117 427.6 Lactobacillaceae yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F452@33958,4HA3Q@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein gnl|extdb|FAM1079-i1-1.1_001003 797515.HMPREF9103_00409 7.9e-114 416.4 Lactobacillaceae yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TQ8K@1239,3F6QR@33958,4HAI8@91061,COG2761@1,COG2761@2 NA|NA|NA Q Thioredoxin gnl|extdb|FAM1079-i1-1.1_001004 511437.Lbuc_0676 2.3e-291 1007.7 Lactobacillaceae pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TP4P@1239,3F4E5@33958,4HA7X@91061,COG1164@1,COG1164@2 NA|NA|NA E oligoendopeptidase F gnl|extdb|FAM1079-i1-1.1_001005 797515.HMPREF9103_01206 6.2e-216 756.5 Lactobacillaceae coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,3F4BZ@33958,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein gnl|extdb|FAM1079-i1-1.1_001006 797515.HMPREF9103_01205 1.4e-297 1028.1 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family gnl|extdb|FAM1079-i1-1.1_001007 797515.HMPREF9103_01204 3.1e-245 854.0 Lactobacillaceae ciaH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TS5K@1239,3F49T@33958,4H9Y1@91061,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain gnl|extdb|FAM1079-i1-1.1_001008 797515.HMPREF9103_01203 4e-127 460.7 Lactobacillaceae Bacteria 1V295@1239,3FC93@33958,4HGW0@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator gnl|extdb|FAM1079-i1-1.1_001009 797515.HMPREF9103_01201 3.2e-65 254.2 Lactobacillaceae Bacteria 1UIGW@1239,2DTIF@1,33KHD@2,3F7X1@33958,4ISGW@91061 NA|NA|NA S GtrA-like protein gnl|extdb|FAM1079-i1-1.1_001010 797515.HMPREF9103_01200 0.0 1208.4 Lactobacillaceae ykcB Bacteria 1TPGI@1239,3F5B1@33958,4HCEY@91061,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase gnl|extdb|FAM1079-i1-1.1_001011 797515.HMPREF9103_01199 7.4e-186 656.4 Lactobacillaceae ykcC ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,3F3X7@33958,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 gnl|extdb|FAM1079-i1-1.1_001012 797515.HMPREF9103_02976 2.1e-120 438.3 Lactobacillaceae mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K16511 ko00000 Bacteria 1UZ7D@1239,3FCFK@33958,4HDV3@91061,COG4862@1,COG4862@2 NA|NA|NA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis gnl|extdb|FAM1079-i1-1.1_001013 797515.HMPREF9103_02975 3.2e-68 264.2 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6HJ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress gnl|extdb|FAM1079-i1-1.1_001014 797515.HMPREF9103_02974 1.2e-140 505.8 Lactobacillaceae yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 Bacteria 1V1TF@1239,3F4U0@33958,4HFNV@91061,COG1234@1,COG1234@2 NA|NA|NA S Metallo-beta-lactamase superfamily gnl|extdb|FAM1079-i1-1.1_000955 525318.HMPREF0497_1311 4.8e-174 617.1 Lactobacillaceae yghZ ko:K19265 ko00000,ko01000 Bacteria 1TRS0@1239,3F414@33958,4HAZ2@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase family protein gnl|extdb|FAM1079-i1-1.1_000964 797515.HMPREF9103_00367 1.4e-42 178.3 Lactobacillaceae hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 ko:K01496,ko:K01497,ko:K01814,ko:K11755 ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024 M00026,M00125 R00425,R04035,R04037,R04640 RC00002,RC00293,RC00945,RC01055,RC02504 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186 Bacteria 1UYNA@1239,3F73W@33958,4HA9R@91061,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP gnl|extdb|FAM1079-i1-1.1_000983 797515.HMPREF9103_00387 2.3e-31 141.0 Lactobacillaceae yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1VEKA@1239,3F843@33958,4HNJR@91061,COG0762@1,COG0762@2 NA|NA|NA S YGGT family gnl|extdb|FAM1079-i1-1.1_001015 797515.HMPREF9103_02973 1e-89 335.9 Lactobacillaceae traP GO:0005575,GO:0016020 1.14.99.57,6.2.1.3 ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1V501@1239,3F3UU@33958,4HHA2@91061,COG2329@1,COG2329@2 NA|NA|NA S enzyme involved in biosynthesis of extracellular polysaccharides gnl|extdb|FAM1079-i1-1.1_001036 525318.HMPREF0497_1690 7.1e-90 336.7 Lactobacillaceae Bacteria 1V14J@1239,3F4SX@33958,4HCBK@91061,COG4843@1,COG4843@2 NA|NA|NA S UPF0316 protein gnl|extdb|FAM1079-i1-1.1_001037 797515.HMPREF9103_01613 4.5e-166 590.5 Lactobacillaceae rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469,ko:K06993 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V4A0@1239,3F3RG@33958,4HHJ9@91061,COG0328@1,COG0328@2,COG3341@1,COG3341@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids gnl|extdb|FAM1079-i1-1.1_001038 797515.HMPREF9103_01612 4.7e-76 290.4 Lactobacillaceae Bacteria 1VXE5@1239,2F6G8@1,33YZB@2,3F67Q@33958,4HWYE@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001039 797515.HMPREF9103_01611 6.2e-235 819.7 Lactobacillaceae codA 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 Bacteria 1TRK2@1239,3F4JP@33958,4HAAV@91061,COG0402@1,COG0402@2 NA|NA|NA F cytosine deaminase gnl|extdb|FAM1079-i1-1.1_001040 797515.HMPREF9103_01610 5.8e-239 833.2 Lactobacillaceae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,3F5BE@33958,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P Potassium uptake protein gnl|extdb|FAM1079-i1-1.1_001041 797515.HMPREF9103_01609 6.9e-116 423.3 Lactobacillaceae ktrA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ9H@1239,3F5G0@33958,4HBPH@91061,COG0569@1,COG0569@2 NA|NA|NA P domain protein gnl|extdb|FAM1079-i1-1.1_001042 797515.HMPREF9103_01602 8.5e-87 326.2 Lactobacillaceae yveA 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria 1VF7P@1239,3FC9Z@33958,4HQSB@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family gnl|extdb|FAM1079-i1-1.1_001043 797515.HMPREF9103_01600 4.3e-172 610.5 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1UYWR@1239,3F5V1@33958,4HDC6@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase gnl|extdb|FAM1079-i1-1.1_001044 797515.HMPREF9103_01599 1.1e-158 565.8 Lactobacillaceae Bacteria 1U5KN@1239,29NU6@1,309SA@2,3F65P@33958,4IFBK@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001046 1122149.BACN01000100_gene1980 6.4e-39 166.4 Lactobacillaceae yefM 2.3.1.15 ko:K08591,ko:K19158,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1U6CD@1239,3F7KJ@33958,4IG41@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module gnl|extdb|FAM1079-i1-1.1_001047 1138822.PL11_10585 1.2e-45 189.1 Lactobacillaceae yafQ GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042710,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043565,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044764,GO:0044877,GO:0046483,GO:0046677,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 ko:K19157 ko00000,ko01000,ko02048 Bacteria 1U6BU@1239,3F7JG@33958,4IG3F@91061,COG3041@1,COG3041@2 NA|NA|NA S Bacterial toxin of type II toxin-antitoxin system, YafQ gnl|extdb|FAM1079-i1-1.1_001049 1136177.KCA1_2801 6.9e-25 120.9 Bacteria Bacteria COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score gnl|extdb|FAM1079-i1-1.1_001050 797515.HMPREF9103_01596 5.3e-63 246.9 Lactobacillaceae Bacteria 1U6QQ@1239,3F8BG@33958,4IGHZ@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001052 525318.HMPREF0497_1684 5.4e-89 334.0 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) gnl|extdb|FAM1079-i1-1.1_001053 1423734.JCM14202_1723 8e-119 434.5 Lactobacillaceae norB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K08170 M00702 ko00000,ko00002,ko01504,ko02000 2.A.1.3.23,2.A.1.3.59 Bacteria 1TPV3@1239,3F5DE@33958,4HCJN@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator gnl|extdb|FAM1079-i1-1.1_001054 1229756.C269_02065 1.5e-16 92.8 Bacilli Bacteria 1V4SH@1239,4IR3T@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM1079-i1-1.1_001055 797515.HMPREF9103_01591 3e-153 547.7 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase gnl|extdb|FAM1079-i1-1.1_001056 525318.HMPREF0497_0886 4e-129 469.2 Lactobacillaceae ko:K16076,ko:K18093 ko01501,ko02020,map01501,map02020 M00745 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 1.B.1.1.4,1.B.1.1.5,1.B.25.1.1 Bacteria 1VXP5@1239,3F5AT@33958,4HWZF@91061,COG3203@1,COG3203@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane gnl|extdb|FAM1079-i1-1.1_001058 797515.HMPREF9103_01589 2e-121 441.8 Lactobacillaceae yrkL ko:K11748 ko00000,ko02000 2.A.37.1.2 Bacteria 1V4UF@1239,3F6XY@33958,4HIR3@91061,COG2249@1,COG2249@2 NA|NA|NA S Flavodoxin-like fold gnl|extdb|FAM1079-i1-1.1_001059 797515.HMPREF9103_01588 2.2e-72 278.1 Lactobacillaceae Bacteria 1VN90@1239,3F6MQ@33958,4HRIC@91061,COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein gnl|extdb|FAM1079-i1-1.1_001060 525318.HMPREF0497_1674 0.0 1087.8 Lactobacillaceae clpE2 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F9FZ@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family gnl|extdb|FAM1079-i1-1.1_001061 797515.HMPREF9103_01585 2.1e-31 141.0 Lactobacillaceae cspC ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7FW@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein gnl|extdb|FAM1079-i1-1.1_001062 797515.HMPREF9103_01583 1.3e-172 613.2 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F4RM@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA S Alpha beta gnl|extdb|FAM1079-i1-1.1_001064 525318.HMPREF0497_1669 1.1e-184 652.5 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid gnl|extdb|FAM1079-i1-1.1_001065 797515.HMPREF9103_01578 2.8e-176 626.3 Lactobacillaceae yvcC Bacteria 1V0EB@1239,3F8V5@33958,4IGW5@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein gnl|extdb|FAM1079-i1-1.1_001066 797515.HMPREF9103_01577 4e-147 527.3 Lactobacillaceae modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028,ko:K05776 ko02010,map02010 M00189,M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 1TRR4@1239,3F3ZZ@33958,4HB4U@91061,COG1119@1,COG1119@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM1079-i1-1.1_001067 797515.HMPREF9103_01575 1.5e-197 695.3 Lactobacillaceae ilvC 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPI7@1239,3F4YR@33958,4HADK@91061,COG0059@1,COG0059@2 NA|NA|NA H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate gnl|extdb|FAM1079-i1-1.1_001068 797515.HMPREF9103_01574 0.0 1117.1 Lactobacillaceae ilvB 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iYO844.BSU28310 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM1079-i1-1.1_001069 797515.HMPREF9103_01573 1.8e-133 481.9 Lactobacillaceae Bacteria 1UKXW@1239,29XNW@1,30JEC@2,3F7S0@33958,4ITMI@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001070 797515.HMPREF9103_01572 3.6e-238 830.5 Lactobacillaceae ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP22@1239,3F5KK@33958,4H9NK@91061,COG1171@1,COG1171@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA gnl|extdb|FAM1079-i1-1.1_001071 525318.HMPREF0497_1658 0.0 1122.5 Lactobacillaceae ilvD 4.2.1.9 ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iAF987.Gmet_1259 Bacteria 1TP1R@1239,3F45Q@33958,4H9ZG@91061,COG0129@1,COG0129@2 NA|NA|NA EG Belongs to the IlvD Edd family gnl|extdb|FAM1079-i1-1.1_001072 797515.HMPREF9103_01569 6.1e-169 600.1 Lactobacillaceae yocS ko:K03453 ko00000 2.A.28 Bacteria 1TP85@1239,3F41E@33958,4HBG6@91061,COG0385@1,COG0385@2 NA|NA|NA S SBF-like CPA transporter family (DUF4137) gnl|extdb|FAM1079-i1-1.1_001073 797515.HMPREF9103_01568 4.1e-192 677.2 Lactobacillaceae 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F4PZ@33958,4HVEG@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase gnl|extdb|FAM1079-i1-1.1_001074 797515.HMPREF9103_01567 4.1e-65 253.8 Lactobacillaceae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1U6IJ@1239,3F7ZH@33958,4IGAY@91061,COG0509@1,COG0509@2 NA|NA|NA E glycine cleavage gnl|extdb|FAM1079-i1-1.1_001075 525318.HMPREF0497_1573 1.5e-33 148.3 Lactobacillaceae Bacteria 1U6KC@1239,29PH8@1,30AFD@2,3F83D@33958,4IGD6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001076 797515.HMPREF9103_01565 1.1e-53 215.7 Lactobacillaceae Bacteria 1VZZV@1239,2CCD8@1,348YF@2,3F79R@33958,4HZ8C@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001077 797515.HMPREF9103_01564 1.8e-153 548.5 Lactobacillaceae Bacteria 1TRZ4@1239,3F639@33958,4HBR8@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 gnl|extdb|FAM1079-i1-1.1_001078 797515.HMPREF9103_01563 0.0 1583.9 Lactobacillaceae ydgH ko:K06994,ko:K07003 ko00000 Bacteria 1TQ7C@1239,3F9KP@33958,4HBM6@91061,COG2409@1,COG2409@2 NA|NA|NA S MMPL family gnl|extdb|FAM1079-i1-1.1_001079 797515.HMPREF9103_01562 3.5e-180 637.5 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001080 797515.HMPREF9103_01561 0.0 1162.1 Lactobacillaceae pgm GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2N@1239,3F457@33958,4HADU@91061,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain gnl|extdb|FAM1079-i1-1.1_001081 797515.HMPREF9103_01560 5.9e-152 543.5 Lactobacillaceae degV Bacteria 1V289@1239,3F4D9@33958,4I3AR@91061,COG1307@1,COG1307@2 NA|NA|NA S DegV family gnl|extdb|FAM1079-i1-1.1_001082 797515.HMPREF9103_01559 2.3e-230 804.7 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001083 797515.HMPREF9103_01558 7.1e-308 1062.4 Lactobacillaceae ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 1TPW0@1239,3F3ZJ@33958,4HATH@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001084 797515.HMPREF9103_01557 3.4e-126 457.6 Lactobacillaceae Bacteria 1TQWQ@1239,3F5CT@33958,4HFDZ@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase gnl|extdb|FAM1079-i1-1.1_001085 797515.HMPREF9103_01556 9.6e-128 463.0 Lactobacillaceae zupT ko:K07238 ko00000,ko02000 2.A.5.5 Bacteria 1TP7J@1239,3F52T@33958,4HB3R@91061,COG0428@1,COG0428@2 NA|NA|NA P ZIP Zinc transporter gnl|extdb|FAM1079-i1-1.1_001086 525318.HMPREF0497_0886 1.1e-152 547.4 Lactobacillaceae ko:K16076,ko:K18093 ko01501,ko02020,map01501,map02020 M00745 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 1.B.1.1.4,1.B.1.1.5,1.B.25.1.1 Bacteria 1VXP5@1239,3F5AT@33958,4HWZF@91061,COG3203@1,COG3203@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane gnl|extdb|FAM1079-i1-1.1_001087 797515.HMPREF9103_01552 9.7e-163 579.3 Lactobacillaceae ytbE 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4T@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_001088 797515.HMPREF9103_01551 3e-96 357.8 Lactobacillaceae maa GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008374,GO:0008925,GO:0009987,GO:0016043,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 2.3.1.79 ko:K00661 ko00000,ko01000 iAPECO1_1312.APECO1_15532,iECOK1_1307.ECOK1_0441,iECS88_1305.ECS88_0456,iUMN146_1321.UM146_15065,iUTI89_1310.UTI89_C0486 Bacteria 1TQEX@1239,3F68D@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase gnl|extdb|FAM1079-i1-1.1_001089 797515.HMPREF9103_01550 5.3e-283 979.5 Lactobacillaceae araA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 R01761 RC00516 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060 Bacteria 1TPXC@1239,3F4PN@33958,4HAWS@91061,COG2160@1,COG2160@2 NA|NA|NA G Catalyzes the conversion of L-arabinose to L-ribulose gnl|extdb|FAM1079-i1-1.1_001090 797515.HMPREF9103_01549 1.7e-254 884.8 Lactobacillaceae Bacteria 1TREV@1239,3F3ZS@33958,4HAN1@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001091 797515.HMPREF9103_01548 6.7e-209 733.0 Lactobacillaceae araR ko:K02103 ko00000,ko03000 Bacteria 1TP9Q@1239,3F3ZM@33958,4HARD@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001092 797515.HMPREF9103_01547 2e-28 131.0 Lactobacillaceae Bacteria 1U6S9@1239,29PMD@1,30AJJ@2,3F8ED@33958,4IGJT@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001093 797515.HMPREF9103_01546 3.5e-196 690.6 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGJ@1239,3F48R@33958,4HADZ@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose gnl|extdb|FAM1079-i1-1.1_001094 1423743.JCM14108_2228 5.7e-215 753.4 Lactobacillaceae ydjK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08369 ko00000,ko02000 2.A.1 Bacteria 1UJGJ@1239,3FBY5@33958,4IT9D@91061,COG2271@1,COG2271@2 NA|NA|NA G Sugar (and other) transporter gnl|extdb|FAM1079-i1-1.1_001095 797515.HMPREF9103_01543 3.4e-166 590.9 Lactobacillaceae prpB 4.1.3.30,4.1.3.32 ko:K03417,ko:K20454 ko00640,ko00760,ko01120,map00640,map00760,map01120 R00409,R01355 RC00286,RC00287,RC01810 ko00000,ko00001,ko01000 Bacteria 1UN2U@1239,3F4VK@33958,4IU5Q@91061,COG2513@1,COG2513@2 NA|NA|NA G Phosphoenolpyruvate phosphomutase gnl|extdb|FAM1079-i1-1.1_001096 797515.HMPREF9103_01542 2.3e-136 491.5 Lactobacillaceae bcpA GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008807,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016772,GO:0016780,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249,GO:0055114 4.1.1.3 ko:K01003 ko00620,ko01100,map00620,map01100 R00217 RC00040 ko00000,ko00001,ko01000 Bacteria 1U6FU@1239,3F7TN@33958,4IG7T@91061,COG2513@1,COG2513@2 NA|NA|NA G Phosphoenolpyruvate phosphomutase gnl|extdb|FAM1079-i1-1.1_001097 797515.HMPREF9103_02194 3.3e-15 87.8 Lactobacillaceae Bacteria 1U65U@1239,29PCD@1,30A41@2,3F74X@33958,4IFVQ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001098 797515.HMPREF9103_01539 1.4e-110 405.6 Lactobacillaceae Bacteria 1V2M4@1239,3F7D4@33958,4HMH5@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_001100 797515.HMPREF9103_01537 1.7e-117 428.7 Lactobacillaceae Bacteria 1U6B3@1239,2A62H@1,30A7W@2,3F7HS@33958,4IG2K@91061 NA|NA|NA S Domain of unknown function (DUF4811) gnl|extdb|FAM1079-i1-1.1_001101 797515.HMPREF9103_01536 8.2e-221 772.7 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction gnl|extdb|FAM1079-i1-1.1_001102 797515.HMPREF9103_01535 2.6e-28 130.6 Lactobacillaceae Bacteria 1U6N4@1239,29PIQ@1,30AGV@2,3F86D@33958,4IGEY@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001103 797515.HMPREF9103_01534 4.1e-192 677.2 Lactobacillaceae exuR ko:K02529 ko00000,ko03000 Bacteria 1UCPU@1239,3F5RB@33958,4HDJ7@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein domain gnl|extdb|FAM1079-i1-1.1_001104 797515.HMPREF9103_01532 1.4e-283 981.5 Lactobacillaceae uxaC 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRI0@1239,3F4QN@33958,4HCGI@91061,COG1904@1,COG1904@2 NA|NA|NA G glucuronate isomerase gnl|extdb|FAM1079-i1-1.1_001105 797515.HMPREF9103_01531 0.0 1092.8 Lactobacillaceae 5.1.2.7 ko:K21619 ko00040,ko01100,map00040,map01100 R11624 ko00000,ko00001,ko01000 Bacteria 1TQT7@1239,2BXG3@1,2Z82R@2,3F438@33958,4HDJZ@91061 NA|NA|NA S tagaturonate epimerase gnl|extdb|FAM1079-i1-1.1_001106 797515.HMPREF9103_01530 6.6e-273 946.0 Lactobacillaceae yjmB ko:K03292 ko00000 2.A.2 Bacteria 1TRYR@1239,3F51T@33958,4HCTH@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_001107 511437.Lbuc_0081 6.7e-92 343.6 Lactobacillaceae eda 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1TS0F@1239,3F6AY@33958,4HG4G@91061,COG0800@1,COG0800@2 NA|NA|NA G KDPG and KHG aldolase gnl|extdb|FAM1079-i1-1.1_001108 511437.Lbuc_0080 1.1e-122 446.4 Lactobacillaceae kdgK 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRRY@1239,3F4FT@33958,4HBH6@91061,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM1079-i1-1.1_001109 1071400.LBUCD034_0074 5.7e-74 284.3 Lactobacillaceae kguE 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V82S@1239,3FBQ6@33958,4IRUU@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel gnl|extdb|FAM1079-i1-1.1_001110 1136177.KCA1_2946 2.2e-110 405.6 Lactobacillaceae kdgT GO:0003674,GO:0005215,GO:0005342,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015355,GO:0015649,GO:0015672,GO:0015711,GO:0015718,GO:0015749,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044464,GO:0046411,GO:0046942,GO:0046943,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039 ko:K02526 ko00000,ko02000 2.A.10.1 iECH74115_1262.ECH74115_5364,iECSP_1301.ECSP_4972,iG2583_1286.G2583_4714,iUTI89_1310.UTI89_C4493 Bacteria 1UPH1@1239,28H7K@1,2Z7JT@2,3F5NY@33958,4HE88@91061 NA|NA|NA P 2-keto-3-deoxygluconate permease gnl|extdb|FAM1079-i1-1.1_001051 797515.HMPREF9103_01595 1e-196 692.6 Lactobacillaceae yeaN GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 1TP9R@1239,3F52B@33958,4H9YZ@91061,COG2807@1,COG2807@2 NA|NA|NA P Transporter, major facilitator family protein gnl|extdb|FAM1079-i1-1.1_001063 797515.HMPREF9103_01582 6.4e-156 556.6 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U511@1239,3F9JJ@33958,4I3YH@91061,COG3001@1,COG3001@2 NA|NA|NA G Seadornavirus VP7 gnl|extdb|FAM1079-i1-1.1_001113 797515.HMPREF9103_01852 5.9e-129 466.8 Lactobacillaceae srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V83Z@1239,3F54V@33958,4HJV9@91061,COG3764@1,COG3764@2 NA|NA|NA M sortase family gnl|extdb|FAM1079-i1-1.1_001114 797515.HMPREF9103_01853 4.9e-76 290.4 Lactobacillaceae ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1V6SG@1239,3F74A@33958,4HIZN@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family gnl|extdb|FAM1079-i1-1.1_001115 797515.HMPREF9103_01854 6.4e-142 510.0 Lactobacillaceae Bacteria 1V9FK@1239,29SV9@1,31VZX@2,3FBQI@33958,4IRY8@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001116 797515.HMPREF9103_01855 1.7e-262 911.4 Lactobacillaceae murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1VT78@1239,3F4SK@33958,4HACR@91061,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein gnl|extdb|FAM1079-i1-1.1_001117 797515.HMPREF9103_01856 2.4e-249 867.8 Lactobacillaceae cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F46Q@33958,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity gnl|extdb|FAM1079-i1-1.1_001118 797515.HMPREF9103_01857 3.8e-60 237.3 Lactobacillaceae acpS 2.7.6.3,2.7.8.7,5.1.1.1 ko:K00950,ko:K00997,ko:K01775 ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502 M00126,M00841 R00401,R01625,R03503 RC00002,RC00017,RC00285 ko00000,ko00001,ko00002,ko01000,ko01011 iYO844.BSU04620 Bacteria 1VA0T@1239,3F6HC@33958,4HKBI@91061,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein gnl|extdb|FAM1079-i1-1.1_001119 797515.HMPREF9103_01858 2.4e-214 751.1 Lactobacillaceae alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1TNYY@1239,3F3X2@33958,4HA95@91061,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids gnl|extdb|FAM1079-i1-1.1_001120 797515.HMPREF9103_01859 8.4e-47 192.6 Lactobacillaceae Bacteria 1U6PH@1239,2AFAZ@1,315AC@2,3F897@33958,4IGGG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001121 797515.HMPREF9103_01860 4.2e-62 243.8 Lactobacillaceae ndoA ko:K07171 ko00000,ko01000,ko02048 Bacteria 1V6DK@1239,3F6Y9@33958,4HGXF@91061,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module gnl|extdb|FAM1079-i1-1.1_001122 797515.HMPREF9103_01861 6.2e-61 240.0 Lactobacillaceae Bacteria 1VA4E@1239,2D5AS@1,32TIN@2,3F79V@33958,4HMJT@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001123 797515.HMPREF9103_01862 4.3e-259 900.2 Lactobacillaceae yfiU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1VSW8@1239,3F3XF@33958,4HD3T@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001124 797515.HMPREF9103_01863 1.1e-113 416.0 Lactobacillaceae Bacteria 1TR5G@1239,3F3JY@33958,4H9ZA@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain gnl|extdb|FAM1079-i1-1.1_001125 797515.HMPREF9103_01864 2.6e-172 611.3 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family gnl|extdb|FAM1079-i1-1.1_001126 797515.HMPREF9103_01865 5.1e-104 383.6 Lactobacillaceae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1V3NB@1239,3F3VZ@33958,4HH2Z@91061,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis gnl|extdb|FAM1079-i1-1.1_001127 797515.HMPREF9103_01866 0.0 2287.3 Lactobacillaceae mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPF1@1239,3F4KU@33958,4H9NB@91061,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site gnl|extdb|FAM1079-i1-1.1_001128 797515.HMPREF9103_01867 2e-246 858.2 Lactobacillaceae yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F4BV@33958,4HACG@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein gnl|extdb|FAM1079-i1-1.1_001129 797515.HMPREF9103_01868 2.1e-39 167.9 Lactobacillaceae yabO GO:0008150,GO:0040007 Bacteria 1VEI5@1239,3F7JX@33958,4HKJJ@91061,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein gnl|extdb|FAM1079-i1-1.1_001130 797515.HMPREF9103_01869 6e-54 216.9 Lactobacillaceae divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 1VKC5@1239,3F6SC@33958,4HR53@91061,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator gnl|extdb|FAM1079-i1-1.1_001131 797515.HMPREF9103_01870 3.3e-57 228.0 Lactobacillaceae yabR ko:K07570,ko:K07571 ko00000 Bacteria 1V6FE@1239,3F6HV@33958,4HIKM@91061,COG1098@1,COG1098@2 NA|NA|NA J RNA binding gnl|extdb|FAM1079-i1-1.1_001132 797515.HMPREF9103_01871 9.9e-266 922.2 Lactobacillaceae tilS 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPXP@1239,3F4GY@33958,4H9ZM@91061,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine gnl|extdb|FAM1079-i1-1.1_001133 797515.HMPREF9103_01872 8.4e-96 356.3 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F56C@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family gnl|extdb|FAM1079-i1-1.1_001134 797515.HMPREF9103_01873 0.0 1221.1 Lactobacillaceae ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPTV@1239,3F49Z@33958,4HAJB@91061,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins gnl|extdb|FAM1079-i1-1.1_001135 797515.HMPREF9103_01874 5.9e-163 580.1 Lactobacillaceae hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1TRCH@1239,3F42B@33958,4HAFR@91061,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress gnl|extdb|FAM1079-i1-1.1_001136 797515.HMPREF9103_01875 1.1e-192 679.1 Lactobacillaceae dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4C6@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines gnl|extdb|FAM1079-i1-1.1_001137 797515.HMPREF9103_01876 3.8e-295 1020.0 Lactobacillaceae lysS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP2P@1239,3F439@33958,4H9X4@91061,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family gnl|extdb|FAM1079-i1-1.1_001141 797515.HMPREF9103_01444 3.7e-222 777.3 Lactobacillaceae gltP GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015849,GO:0016020,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702,GO:0071944 ko:K03309,ko:K11102 ko00000,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2 iPC815.YPO0254,iYO844.BSU10220 Bacteria 1TPME@1239,3F4Q2@33958,4H9T7@91061,COG1301@1,COG1301@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gnl|extdb|FAM1079-i1-1.1_001142 797515.HMPREF9103_01445 2.7e-309 1067.0 Lactobacillaceae mco Bacteria 1TQSU@1239,3F3XB@33958,4HDD6@91061,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase gnl|extdb|FAM1079-i1-1.1_001143 797515.HMPREF9103_01446 1.1e-67 262.3 Lactobacillaceae Bacteria 1U708@1239,29PSZ@1,30AR5@2,3F8T2@33958,4IGUJ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001144 797515.HMPREF9103_01447 1.8e-37 161.4 Lactobacillaceae Bacteria 1U6GT@1239,29PEG@1,30ACN@2,3F7W3@33958,4IG8Z@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001145 797515.HMPREF9103_01448 1.5e-106 392.1 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1TTGQ@1239,3F5T3@33958,4IF6G@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family gnl|extdb|FAM1079-i1-1.1_001148 797515.HMPREF9103_01454 3.2e-204 717.6 Lactobacillaceae 3.5.1.6,3.5.1.87,3.5.3.9 ko:K02083,ko:K06016 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 M00046 R00905,R02423,R04666 RC00064,RC00096 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TQ0P@1239,3F5V9@33958,4HAE4@91061,COG0624@1,COG0624@2 NA|NA|NA E Peptidase family M20/M25/M40 gnl|extdb|FAM1079-i1-1.1_001150 797515.HMPREF9103_01456 1.5e-113 415.6 Lactobacillaceae thiF 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 1TQ3U@1239,3F3QT@33958,4HBGP@91061,COG0476@1,COG0476@2 NA|NA|NA H ThiF family gnl|extdb|FAM1079-i1-1.1_001151 797515.HMPREF9103_01457 2.9e-27 127.1 Lactobacillaceae thiS ko:K03154 ko04122,map04122 ko00000,ko00001 Bacteria 1VKB4@1239,3F8K0@33958,4IGPJ@91061,COG2104@1,COG2104@2 NA|NA|NA H ThiS family gnl|extdb|FAM1079-i1-1.1_001152 797515.HMPREF9103_01458 2.1e-106 391.7 Lactobacillaceae thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3ZR@1239,3F5MA@33958,4HIHG@91061,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) gnl|extdb|FAM1079-i1-1.1_001153 797515.HMPREF9103_01459 8.2e-159 566.2 Lactobacillaceae Bacteria 1UN2T@1239,3F4BE@33958,4IU5P@91061,COG0726@1,COG0726@2 NA|NA|NA G Carbohydrate esterase, sialic acid-specific acetylesterase gnl|extdb|FAM1079-i1-1.1_001154 511437.Lbuc_0217 9.7e-67 260.0 Lactobacillaceae Bacteria 1V7A7@1239,3F63T@33958,4HIII@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding gnl|extdb|FAM1079-i1-1.1_001155 908339.HMPREF9265_1577 1.4e-168 599.0 Lactobacillaceae adh 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F42F@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase gnl|extdb|FAM1079-i1-1.1_001156 797515.HMPREF9103_01461 2.4e-161 574.7 Lactobacillaceae akr5f 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase gnl|extdb|FAM1079-i1-1.1_001157 797515.HMPREF9103_01462 1.1e-156 559.3 Lactobacillaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UZXK@1239,3F41Q@33958,4HUWT@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001158 1071400.LBUCD034_2259 2.1e-266 924.5 Lactobacillaceae gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 1TP4I@1239,3F3S8@33958,4H9NC@91061,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnl|extdb|FAM1079-i1-1.1_001159 797515.HMPREF9103_01467 6.8e-281 972.6 Lactobacillaceae zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 1TPYF@1239,3F48G@33958,4HA73@91061,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone gnl|extdb|FAM1079-i1-1.1_001160 797515.HMPREF9103_01468 8.1e-113 413.3 Lactobacillaceae Bacteria 1U59G@1239,29NNA@1,309K8@2,3F59P@33958,4IF0U@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001161 797515.HMPREF9103_01469 9.6e-209 732.6 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001162 797515.HMPREF9103_01470 2.2e-81 308.1 Lactobacillaceae nrdI ko:K03647 ko00000 Bacteria 1V71V@1239,3F6JF@33958,4HIW7@91061,COG1780@1,COG1780@2 NA|NA|NA F Belongs to the NrdI family gnl|extdb|FAM1079-i1-1.1_001164 797515.HMPREF9103_01472 5.4e-251 873.2 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain gnl|extdb|FAM1079-i1-1.1_001165 797515.HMPREF9103_01473 1.6e-70 271.9 Lactobacillaceae Bacteria 1U6KN@1239,29PHG@1,30AFM@2,3F83U@33958,4IGDE@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001166 797515.HMPREF9103_01474 1.1e-163 582.4 Lactobacillaceae ytbE 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4T@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_001167 797515.HMPREF9103_01475 0.0 1489.9 Lactobacillaceae yfgQ ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 1TPF5@1239,3F4Y1@33958,4H9ZI@91061,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase gnl|extdb|FAM1079-i1-1.1_001169 797515.HMPREF9103_01477 4.3e-92 344.0 Lactobacillaceae M1-874 ko:K13638,ko:K13640 ko00000,ko03000 Bacteria 1V7Z4@1239,3F5IX@33958,4HJXK@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) gnl|extdb|FAM1079-i1-1.1_001170 797515.HMPREF9103_01478 0.0 1717.6 Lactobacillaceae adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 Bacteria 1TPB4@1239,3F3RN@33958,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family gnl|extdb|FAM1079-i1-1.1_001171 797515.HMPREF9103_01479 4.3e-114 417.5 Lactobacillaceae ko:K07090 ko00000 Bacteria 1V75K@1239,3F6BU@33958,4HEE8@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM1079-i1-1.1_001172 797515.HMPREF9103_01480 2.4e-93 348.2 Lactobacillaceae Bacteria 1VEB3@1239,3F7VW@33958,4HKVP@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001173 797515.HMPREF9103_01481 9.6e-115 419.5 Lactobacillaceae ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,3F3PN@33958,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. gnl|extdb|FAM1079-i1-1.1_001174 797515.HMPREF9103_01482 3.4e-124 451.1 Lactobacillaceae Bacteria 1V5G2@1239,31PIN@2,3F6X9@33958,4HIRV@91061,arCOG05209@1 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001175 797515.HMPREF9103_01483 6.4e-90 336.7 Lactobacillaceae ybaK ko:K03976 ko00000,ko01000,ko03016 Bacteria 1V6JF@1239,3FC62@33958,4HHFK@91061,COG2606@1,COG2606@2 NA|NA|NA J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily gnl|extdb|FAM1079-i1-1.1_001176 797515.HMPREF9103_01484 4.7e-134 483.8 Lactobacillaceae gntR1 ko:K03710 ko00000,ko03000 Bacteria 1V0UW@1239,3FBE1@33958,4IPQ0@91061,COG2188@1,COG2188@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001177 797515.HMPREF9103_01485 0.0 1647.1 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase gnl|extdb|FAM1079-i1-1.1_001178 797515.HMPREF9103_01486 1.5e-247 861.7 Lactobacillaceae Bacteria 1U5C7@1239,3F5HV@33958,4IF3F@91061,COG4097@1,COG4097@2 NA|NA|NA P FAD-binding domain gnl|extdb|FAM1079-i1-1.1_001179 797515.HMPREF9103_01487 2.1e-143 515.0 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1VVZ1@1239,3F6NE@33958,4HWJX@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein gnl|extdb|FAM1079-i1-1.1_001180 1423780.LOT_0711 1.7e-47 195.7 Lactobacillaceae Bacteria 1VBTI@1239,3F7N4@33958,4HKRR@91061,COG3976@1,COG3976@2 NA|NA|NA S FMN_bind gnl|extdb|FAM1079-i1-1.1_001181 797515.HMPREF9103_01489 1.1e-264 918.7 Lactobacillaceae nylA 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 1TPGJ@1239,3F4UM@33958,4HBE7@91061,COG0154@1,COG0154@2 NA|NA|NA J Belongs to the amidase family gnl|extdb|FAM1079-i1-1.1_001182 797515.HMPREF9103_01490 3e-170 604.4 Lactobacillaceae rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TSM6@1239,3F50K@33958,4HA7M@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil gnl|extdb|FAM1079-i1-1.1_001183 797515.HMPREF9103_01491 3.3e-80 304.3 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein gnl|extdb|FAM1079-i1-1.1_001184 797515.HMPREF9103_01492 3.3e-194 684.1 Lactobacillaceae lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F4UZ@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase gnl|extdb|FAM1079-i1-1.1_001112 797515.HMPREF9103_01851 4.1e-191 674.1 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001147 797515.HMPREF9103_01450 2.4e-184 651.4 Lactobacillaceae qor 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TRNC@1239,3F48F@33958,4HATC@91061,COG0604@1,COG0604@2 NA|NA|NA C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily gnl|extdb|FAM1079-i1-1.1_001149 797515.HMPREF9103_01455 7e-136 490.0 Lactobacillaceae thiG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947 Bacteria 1TQZ1@1239,3F4UA@33958,4HBSI@91061,COG2022@1,COG2022@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S gnl|extdb|FAM1079-i1-1.1_001163 797515.HMPREF9103_01471 0.0 1955.6 Lactobacillaceae Bacteria 1TPVY@1239,3F4AK@33958,4HD9X@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO gnl|extdb|FAM1079-i1-1.1_001186 1033837.WANG_1507 4.4e-122 444.1 Lactobacillaceae 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1VA24@1239,3F6NY@33958,4HMSH@91061,COG2365@1,COG2365@2 NA|NA|NA T Pfam:Y_phosphatase3C gnl|extdb|FAM1079-i1-1.1_001187 1033837.WANG_1506 2.3e-54 218.0 Lactobacillaceae pduU ko:K04031 ko00000 Bacteria 1VB54@1239,3FBCN@33958,4HH8R@91061,COG4810@1,COG4810@2 NA|NA|NA E BMC gnl|extdb|FAM1079-i1-1.1_001189 557436.Lreu_1736 3.1e-46 191.4 Lactobacillaceae pduO Bacteria 1V5C7@1239,3F6JA@33958,4HHN9@91061,COG3193@1,COG3193@2 NA|NA|NA S Haem-degrading gnl|extdb|FAM1079-i1-1.1_001190 557436.Lreu_1737 8.6e-78 296.6 Lactobacillaceae pduO 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3PI@1239,3F6A2@33958,4IS1D@91061,COG2096@1,COG2096@2 NA|NA|NA S Cobalamin adenosyltransferase gnl|extdb|FAM1079-i1-1.1_001191 557436.Lreu_1738 3.2e-32 144.1 Lactobacillaceae ccmL ko:K04028 ko00000 Bacteria 1VEI4@1239,3F83B@33958,4HNX2@91061,COG4576@1,COG4576@2 NA|NA|NA CQ Ethanolamine utilisation protein EutN/carboxysome gnl|extdb|FAM1079-i1-1.1_001192 557436.Lreu_1739 5.5e-49 200.7 Lactobacillaceae Bacteria 1U6R6@1239,29PKK@1,30AIS@2,3F8CG@33958,4HWXH@91061 NA|NA|NA S Putative propanediol utilisation gnl|extdb|FAM1079-i1-1.1_001193 701521.PECL_1376 4.3e-33 147.1 Lactobacillaceae pduA_4 ko:K04027 ko00000 Bacteria 1VA0E@1239,3F7EA@33958,4HM6R@91061,COG4577@1,COG4577@2 NA|NA|NA CQ BMC gnl|extdb|FAM1079-i1-1.1_001194 557436.Lreu_1742 1.3e-28 133.3 Lactobacillaceae pduK Bacteria 1VEIA@1239,3F80D@33958,4HYCR@91061,COG4577@1,COG4577@2 NA|NA|NA CQ BMC gnl|extdb|FAM1079-i1-1.1_001197 557436.Lreu_1745 2.8e-46 191.8 Lactobacillaceae pduE 4.2.1.28 ko:K13920 ko00640,map00640 R02376 RC00707 ko00000,ko00001,ko01000 Bacteria 1V5ZV@1239,3F6QG@33958,4HJW7@91061,COG4910@1,COG4910@2 NA|NA|NA Q Dehydratase small subunit gnl|extdb|FAM1079-i1-1.1_001198 557436.Lreu_1746 4.3e-71 274.6 Lactobacillaceae pduD 4.2.1.28,4.2.1.30 ko:K06121,ko:K13919 ko00561,ko00640,map00561,map00640 R01047,R02376 RC00429,RC00707 ko00000,ko00001,ko01000 Bacteria 1UT3J@1239,3F5UH@33958,4HFWN@91061,COG4909@1,COG4909@2 NA|NA|NA Q Dehydratase medium subunit gnl|extdb|FAM1079-i1-1.1_001199 557436.Lreu_1747 2.6e-252 877.9 Lactobacillaceae pduC 4.2.1.28 ko:K01699 ko00640,map00640 R02376 RC00707 ko00000,ko00001,ko01000 iLF82_1304.LF82_332,iNRG857_1313.NRG857_10160,iYL1228.KPN_03205 Bacteria 1TPU7@1239,3F5RI@33958,4HDTR@91061,COG4909@1,COG4909@2 NA|NA|NA Q Dehydratase large subunit gnl|extdb|FAM1079-i1-1.1_001200 557436.Lreu_1748 5.2e-85 320.9 Lactobacillaceae pduB Bacteria 1TTAA@1239,3F4UG@33958,4HTBP@91061,COG4816@1,COG4816@2 NA|NA|NA E BMC gnl|extdb|FAM1079-i1-1.1_001201 387344.LVIS_1617 3.4e-32 144.1 Lactobacillaceae pduA_4 ko:K04027 ko00000 Bacteria 1VA0E@1239,3F7H9@33958,4HM6R@91061,COG4577@1,COG4577@2 NA|NA|NA CQ BMC gnl|extdb|FAM1079-i1-1.1_001202 557436.Lreu_1750 3e-57 229.2 Lactobacillaceae Bacteria 1V5UU@1239,3F728@33958,4IST3@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein gnl|extdb|FAM1079-i1-1.1_001203 557436.Lreu_1659 3.4e-95 354.8 Lactobacillaceae Bacteria 1TR1J@1239,3FC9P@33958,4HHQ8@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain gnl|extdb|FAM1079-i1-1.1_001204 349123.Lreu23DRAFT_4645 2e-160 572.0 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3FB6C@33958,4HH0S@91061,COG1052@1,COG1052@2 NA|NA|NA C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_001205 1033837.WANG_1503 9.9e-71 273.5 Lactobacillaceae Bacteria 1U6HF@1239,2EGNI@1,33AEP@2,3F7XJ@33958,4IG9S@91061 NA|NA|NA S Domain of unknown function (DUF4430) gnl|extdb|FAM1079-i1-1.1_001206 797515.HMPREF9103_02283 2.8e-164 584.7 Lactobacillaceae Bacteria 1W217@1239,3F596@33958,4I1VH@91061,COG5066@1,COG5066@2 NA|NA|NA U FFAT motif binding gnl|extdb|FAM1079-i1-1.1_001207 1033837.WANG_1500 7.1e-208 730.7 Lactobacillaceae ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 1VQKC@1239,2EGNI@1,33AEP@2,3F4VE@33958,4HP40@91061 NA|NA|NA S Domain of unknown function (DUF4430) gnl|extdb|FAM1079-i1-1.1_001208 797515.HMPREF9103_02285 3.4e-121 441.0 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family gnl|extdb|FAM1079-i1-1.1_001209 797515.HMPREF9103_02286 2.6e-178 631.7 Lactobacillaceae gntP GO:0003674,GO:0005215,GO:0005342,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015128,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039 ko:K03299,ko:K06155,ko:K16321 ko00000,ko02000 2.A.8,2.A.8.1.3,2.A.8.1.4 Bacteria 1TQ14@1239,3F5T6@33958,4HB0Y@91061,COG2610@1,COG2610@2 NA|NA|NA EG GntP family permease gnl|extdb|FAM1079-i1-1.1_001210 797515.HMPREF9103_00263 7.9e-100 369.8 Lactobacillaceae gpm 3.1.3.73,5.4.2.12 ko:K02226,ko:K15634 ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00122 R01518,R04594,R11173 RC00017,RC00536 ko00000,ko00001,ko00002,ko01000 Bacteria 1VEMM@1239,3F7IC@33958,4HPA5@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family gnl|extdb|FAM1079-i1-1.1_001211 797515.HMPREF9103_01406 3.2e-133 481.1 Lactobacillaceae cobS GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 ko:K02233 ko00860,ko01100,map00860,map01100 M00122 R05223,R11174 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_2837,iECO103_1326.ECO103_2453,iECSP_1301.ECSP_2657,iECs_1301.ECs2787,iG2583_1286.G2583_2502,iUTI89_1310.UTI89_C2230,iZ_1308.Z3152,ic_1306.c2478 Bacteria 1V1QB@1239,3F5PT@33958,4HM4K@91061,COG0368@1,COG0368@2 NA|NA|NA H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate gnl|extdb|FAM1079-i1-1.1_001212 797515.HMPREF9103_02289 7.6e-87 327.0 Bacilli Bacteria 1UHYE@1239,4IU0Q@91061,COG0611@1,COG0611@2 NA|NA|NA H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 gnl|extdb|FAM1079-i1-1.1_001213 797515.HMPREF9103_02290 5.2e-79 300.4 Lactobacillaceae Bacteria 1VE5F@1239,2E87D@1,32VH5@2,3FBQQ@33958,4HQXI@91061 NA|NA|NA S Pfam:DUF3816 gnl|extdb|FAM1079-i1-1.1_001214 936140.AEOT01000002_gene2157 1.1e-107 396.4 Lactobacillaceae ydjP Bacteria 1TR25@1239,3F4FI@33958,4HMJ7@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family gnl|extdb|FAM1079-i1-1.1_001215 1423807.BACO01000036_gene1039 1.8e-29 136.3 Lactobacillaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,3F42Q@33958,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase gnl|extdb|FAM1079-i1-1.1_001216 936140.AEOT01000002_gene2156 3.2e-111 408.3 Lactobacillaceae gltC_1 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ6Y@1239,3F4UJ@33958,4HB94@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain gnl|extdb|FAM1079-i1-1.1_001217 936140.AEOT01000002_gene2155 1.3e-258 898.7 Lactobacillaceae 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 Bacteria 1TP5H@1239,3F5QE@33958,4IS4T@91061,COG4670@1,COG4670@2 NA|NA|NA I Coenzyme A transferase gnl|extdb|FAM1079-i1-1.1_001218 936140.AEOT01000002_gene2154 9e-199 699.5 Lactobacillaceae fabV GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TWIF@1239,3F4NA@33958,4HCSV@91061,COG3007@1,COG3007@2 NA|NA|NA I NAD(P)H binding domain of trans-2-enoyl-CoA reductase gnl|extdb|FAM1079-i1-1.1_001219 220668.lp_3436 1.8e-104 385.6 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family gnl|extdb|FAM1079-i1-1.1_001220 936140.AEOT01000002_gene2152 7.2e-112 410.2 Lactobacillaceae crt 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 R03026 RC00831 ko00000,ko00001,ko01000 Bacteria 1TQ89@1239,3FC7D@33958,4HCH3@91061,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase gnl|extdb|FAM1079-i1-1.1_001221 936140.AEOT01000002_gene2151 2.1e-42 178.7 Lactobacillaceae maoC 4.2.1.55 ko:K17865 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R03027 RC00831 ko00000,ko00001,ko00002,ko01000 Bacteria 1TUJV@1239,3F81H@33958,4IFCX@91061,COG2030@1,COG2030@2 NA|NA|NA I N-terminal half of MaoC dehydratase gnl|extdb|FAM1079-i1-1.1_001222 936140.AEOT01000002_gene2158 3.7e-115 421.4 Lactobacillaceae fabK 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPC3@1239,3F4PC@33958,4H9T0@91061,COG2070@1,COG2070@2 NA|NA|NA S Nitronate monooxygenase gnl|extdb|FAM1079-i1-1.1_001225 1302286.BAOT01000028_gene1347 1.3e-78 299.7 Lactobacillaceae tauB GO:0003674,GO:0003824,GO:0005215,GO:0005342,GO:0005368,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0008559,GO:0015075,GO:0015238,GO:0015399,GO:0015405,GO:0015411,GO:0015711,GO:0015734,GO:0015849,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033283,GO:0034220,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042908,GO:0042910,GO:0043492,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:0098656,GO:1901682,GO:1903825 3.6.3.36 ko:K02049,ko:K10831 ko00920,ko02010,map00920,map02010 M00188,M00435 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4 Bacteria 1TRM6@1239,3FC3F@33958,4HBZ6@91061,COG1116@1,COG1116@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM1079-i1-1.1_001226 1302286.BAOT01000028_gene1346 1.3e-94 353.2 Bacilli tauA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0015711,GO:0015734,GO:0015849,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0042594,GO:0042597,GO:0042908,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0072348 ko:K15551 ko00920,ko02010,map00920,map02010 M00435 ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 iECOK1_1307.ECOK1_0347,iECS88_1305.ECS88_0362,iUMN146_1321.UM146_15535 Bacteria 1TSJU@1239,4HFCZ@91061,COG4521@1,COG4521@2 NA|NA|NA P NMT1-like family gnl|extdb|FAM1079-i1-1.1_001227 1302286.BAOT01000028_gene1345 1e-86 326.6 Lactobacillaceae tauC ko:K15552 ko00920,ko02010,map00920,map02010 M00435 ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 Bacteria 1U217@1239,3FBIE@33958,4HCS9@91061,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM1079-i1-1.1_001228 1302286.BAOT01000028_gene1344 1.1e-242 845.9 Lactobacillaceae naoX Bacteria 1TPWW@1239,3FBSF@33958,4HA11@91061,COG0446@1,COG0446@2,COG0607@1,COG0607@2 NA|NA|NA P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM1079-i1-1.1_001229 568703.LGG_00176 3.4e-178 631.3 Lactobacillaceae ko:K07112 ko00000 Bacteria 1TSNG@1239,3F7RB@33958,4HCH9@91061,COG2391@1,COG2391@2 NA|NA|NA S Sulphur transport gnl|extdb|FAM1079-i1-1.1_001230 1302286.BAOT01000028_gene1342 9.3e-79 300.4 Lactobacillaceae Bacteria 1U35Y@1239,3FBI9@33958,4HCXK@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain gnl|extdb|FAM1079-i1-1.1_001232 525318.HMPREF0497_1185 3.1e-109 401.4 Lactobacillaceae Bacteria 1TSCT@1239,3F3R0@33958,4HD4Z@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain gnl|extdb|FAM1079-i1-1.1_001233 1423780.LOT_1267 1.6e-204 718.8 Lactobacillaceae ko:K03292 ko00000 2.A.2 Bacteria 1TRA5@1239,3F3Z2@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G symporter gnl|extdb|FAM1079-i1-1.1_001234 908339.HMPREF9265_0266 8.1e-30 137.9 Lactobacillaceae Bacteria 1VJGY@1239,3F7KH@33958,4HQEW@91061,COG1917@1,COG1917@2,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein gnl|extdb|FAM1079-i1-1.1_001235 1136177.KCA1_0872 2.3e-82 312.4 Lactobacillaceae citG 2.4.2.52,2.7.7.61 ko:K05966,ko:K13927,ko:K13930 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1TQGQ@1239,3F4SU@33958,4HGCS@91061,COG1767@1,COG1767@2 NA|NA|NA H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase gnl|extdb|FAM1079-i1-1.1_001236 1136177.KCA1_0891 1.6e-44 186.0 Lactobacillaceae citX 2.4.2.52,2.7.7.61 ko:K05964,ko:K13927 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1VB3E@1239,3F74S@33958,4HMZ5@91061,COG3697@1,COG3697@2 NA|NA|NA HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase gnl|extdb|FAM1079-i1-1.1_001237 1122149.BACN01000016_gene621 3.2e-265 920.6 Lactobacillaceae citF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.10 ko:K01643 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_0634 Bacteria 1TPN3@1239,3F4EA@33958,4HAE1@91061,COG3051@1,COG3051@2 NA|NA|NA H Citrate (pro-3S)-lyase alpha chain gnl|extdb|FAM1079-i1-1.1_001238 1114972.AUAW01000026_gene762 1.4e-156 558.9 Lactobacillaceae citE 4.1.3.25,4.1.3.34 ko:K01644,ko:K18292 ko00660,ko01100,ko02020,map00660,map01100,map02020 R00237,R00362 RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko01000 Bacteria 1TPDY@1239,3F47Q@33958,4HD40@91061,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family gnl|extdb|FAM1079-i1-1.1_001239 1114972.AUAW01000026_gene763 2e-35 154.8 Lactobacillaceae citD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K01646 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001 Bacteria 1VEZZ@1239,3F7FR@33958,4HNXD@91061,COG3052@1,COG3052@2 NA|NA|NA C Covalent carrier of the coenzyme of citrate lyase gnl|extdb|FAM1079-i1-1.1_001240 1114972.AUAW01000026_gene764 4.8e-119 434.5 Lactobacillaceae citC 6.2.1.22 ko:K01910 ko02020,map02020 R04449 RC00012,RC00039 ko00000,ko00001,ko01000 Bacteria 1TSGQ@1239,3FB9D@33958,4HDAU@91061,COG3053@1,COG3053@2 NA|NA|NA H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase gnl|extdb|FAM1079-i1-1.1_001241 1122149.BACN01000016_gene618 4.3e-145 521.2 Lactobacillaceae mez_1 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 R00214 RC00105 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,3F4GN@33958,4H9WR@91061,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme, NAD binding domain gnl|extdb|FAM1079-i1-1.1_001242 1291743.LOSG293_080500 1.1e-114 419.9 Lactobacillaceae citR Bacteria 1TPUB@1239,3F4PP@33958,4HCAR@91061,COG2390@1,COG2390@2 NA|NA|NA K sugar-binding domain protein gnl|extdb|FAM1079-i1-1.1_001244 220668.lp_1102 2e-189 668.7 Lactobacillaceae citP ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3F4RH@33958,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region gnl|extdb|FAM1079-i1-1.1_001245 1114972.AUAW01000024_gene54 2.3e-112 412.1 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family gnl|extdb|FAM1079-i1-1.1_001246 1423780.LOT_1567 1.1e-22 112.1 Lactobacillaceae Bacteria 1U81P@1239,29QG5@1,30BFK@2,3FAF2@33958,4IHZ2@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001248 525318.HMPREF0497_1188 3.9e-130 471.5 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1VUFQ@1239,3F4GB@33958,4HVI1@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family gnl|extdb|FAM1079-i1-1.1_001249 1286171.EAL2_c07680 7.8e-158 563.9 Eubacteriaceae opuD ko:K02168,ko:K05020 ko00000,ko02000 2.A.15.1.1,2.A.15.1.11,2.A.15.1.3,2.A.15.1.4 Bacteria 1TRS6@1239,2482K@186801,25VDQ@186806,COG1292@1,COG1292@2 NA|NA|NA U BCCT, betaine/carnitine/choline family transporter gnl|extdb|FAM1079-i1-1.1_001251 1158608.I583_00577 5.9e-98 365.2 Enterococcaceae 2.3.1.21,2.3.1.7 ko:K00624,ko:K08765 ko00071,ko01212,ko03320,ko04146,ko04152,ko04714,ko04920,ko04922,ko04931,map00071,map01212,map03320,map04146,map04152,map04714,map04920,map04922,map04931 R01923,R02396 RC00004,RC00037,RC02816 ko00000,ko00001,ko01000,ko03029 Bacteria 1U2IM@1239,28HC8@1,2Z7P4@2,4B4V2@81852,4IC5R@91061 NA|NA|NA S Choline/Carnitine o-acyltransferase gnl|extdb|FAM1079-i1-1.1_001252 1423780.LOT_1789 1.1e-67 263.5 Lactobacillaceae sixA-2 ko:K08296 ko00000,ko01000 Bacteria 1V8VW@1239,3F69U@33958,4HIYS@91061,COG5607@1,COG5607@2 NA|NA|NA S CHAD gnl|extdb|FAM1079-i1-1.1_001253 1071400.LBUCD034_2413 4.4e-98 364.4 Lactobacillaceae estA Bacteria 1V58J@1239,3FBFX@33958,4HHYR@91061,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase gnl|extdb|FAM1079-i1-1.1_001254 1423780.LOT_1791 9.8e-128 463.0 Lactobacillaceae uppP GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 iYL1228.KPN_03461 Bacteria 1TPFA@1239,3F510@33958,4HB0M@91061,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin gnl|extdb|FAM1079-i1-1.1_001255 1423743.JCM14108_1770 3.1e-104 385.2 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3F59Y@33958,4HBHG@91061,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_001256 1071400.LBUCD034_0108 2.7e-99 368.6 Lactobacillaceae cas2 GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0034641,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.7.7.7 ko:K02342,ko:K09951 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03400 Bacteria 1V0CE@1239,3F4RJ@33958,4HVSS@91061,COG0847@1,COG0847@2 NA|NA|NA L CRISPR-associated protein (Cas_Cas2CT1978) gnl|extdb|FAM1079-i1-1.1_001257 1071400.LBUCD034_0107 2.2e-152 545.0 Lactobacillaceae cas1 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0008821,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0016888,GO:0016889,GO:0016893,GO:0016894,GO:0017108,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048256,GO:0050896,GO:0051276,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K15342 ko00000,ko02048,ko03400 Bacteria 1TQ6F@1239,3F5DG@33958,4HU4Z@91061,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette gnl|extdb|FAM1079-i1-1.1_001258 1423780.LOT_1599 9.1e-84 316.6 Lactobacillaceae casE ko:K19126 ko00000,ko02048 Bacteria 1V5I4@1239,2DKU6@1,30BEK@2,3F5AF@33958,4HWF1@91061 NA|NA|NA S CRISPR_assoc gnl|extdb|FAM1079-i1-1.1_001259 714313.LSA_2p00330 9e-85 320.1 Lactobacillaceae casD ko:K19125 ko00000,ko02048 Bacteria 1V2K8@1239,2DBXF@1,2ZBPB@2,3F68A@33958,4HX6U@91061 NA|NA|NA S CRISPR-associated protein (Cas_Cas5) gnl|extdb|FAM1079-i1-1.1_001260 1071400.LBUCD034_0104 2.6e-149 535.0 Lactobacillaceae casC GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009615,GO:0043207,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071667,GO:0097159,GO:0098542,GO:1901363 ko:K19124 ko00000,ko02048 Bacteria 1TSM0@1239,3F3ZE@33958,4HTJZ@91061,COG1857@1,COG1857@2 NA|NA|NA L CT1975-like protein gnl|extdb|FAM1079-i1-1.1_001262 1071400.LBUCD034_0102 1.7e-227 795.4 Lactobacillaceae casA ko:K07012,ko:K19123 ko00000,ko01000,ko02048 Bacteria 1TSVP@1239,3F55R@33958,4HUQ4@91061,COG1203@1,COG1203@2 NA|NA|NA L the current gene model (or a revised gene model) may contain a frame shift gnl|extdb|FAM1079-i1-1.1_001263 1423780.LOT_1593 0.0 1258.4 Lactobacillaceae cas3 ko:K07012,ko:K19123 ko00000,ko01000,ko02048 Bacteria 1TQ9B@1239,3F4VV@33958,4HAH7@91061,COG1203@1,COG1203@2 NA|NA|NA L CRISPR-associated helicase cas3 gnl|extdb|FAM1079-i1-1.1_001264 984892.SPSE_1640 3.8e-08 63.5 Staphylococcaceae Bacteria 1TY5I@1239,2DJB9@1,305DF@2,4H06I@90964,4I102@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001196 557436.Lreu_1744 1.1e-275 955.7 Lactobacillaceae pduG ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TQMU@1239,3F5AC@33958,4HC7H@91061,COG0849@1,COG0849@2 NA|NA|NA D Diol dehydratase reactivase ATPase-like domain gnl|extdb|FAM1079-i1-1.1_001195 557436.Lreu_1743 3.5e-32 144.4 Lactobacillaceae pduH Bacteria 1VC2J@1239,2EB43@1,3354T@2,3F804@33958,4HRRX@91061 NA|NA|NA S Dehydratase medium subunit gnl|extdb|FAM1079-i1-1.1_001223 1121105.ATXL01000019_gene1512 6.1e-18 97.4 Enterococcaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,4AZVB@81852,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA G Sugar transport protein gnl|extdb|FAM1079-i1-1.1_001231 525318.HMPREF0497_1008 3.4e-105 388.3 Lactobacillaceae 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V851@1239,3F55V@33958,4HJB2@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family gnl|extdb|FAM1079-i1-1.1_001243 1122149.BACN01000016_gene616 5.5e-80 304.3 Lactobacillaceae ydjP Bacteria 1TR25@1239,3F4FI@33958,4HMJ7@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family gnl|extdb|FAM1079-i1-1.1_001261 1071400.LBUCD034_0103 9.9e-66 256.5 Lactobacillaceae casB ko:K19046 ko00000,ko02048 Bacteria 1VB3D@1239,2CK1Q@1,32UPV@2,3F6J5@33958,4HZ02@91061 NA|NA|NA S CRISPR-associated protein Cse2 (CRISPR_cse2) gnl|extdb|FAM1079-i1-1.1_001267 797515.HMPREF9103_00429 3.4e-115 421.0 Lactobacillaceae phoU ko:K02039 ko00000 Bacteria 1URN3@1239,3F61R@33958,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake gnl|extdb|FAM1079-i1-1.1_001268 797515.HMPREF9103_00430 1.9e-141 508.4 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_001269 797515.HMPREF9103_00431 4.9e-148 530.4 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_001270 797515.HMPREF9103_00432 2.8e-157 561.2 Lactobacillaceae pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3F412@33958,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease protein PstA gnl|extdb|FAM1079-i1-1.1_001271 797515.HMPREF9103_00433 1e-149 536.2 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane gnl|extdb|FAM1079-i1-1.1_001272 797515.HMPREF9103_00434 1.1e-161 575.9 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate gnl|extdb|FAM1079-i1-1.1_001274 797515.HMPREF9103_00436 1.6e-129 468.8 Lactobacillaceae Bacteria 1TPWS@1239,3FC91@33958,4H9KP@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator gnl|extdb|FAM1079-i1-1.1_001275 797515.HMPREF9103_00437 4.2e-193 680.6 Lactobacillaceae minJ Bacteria 1TSBA@1239,3F4TP@33958,4HA05@91061,COG0265@1,COG0265@2 NA|NA|NA O Domain present in PSD-95, Dlg, and ZO-1/2. gnl|extdb|FAM1079-i1-1.1_001276 797515.HMPREF9103_00438 1.2e-210 738.8 Lactobacillaceae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1TPSB@1239,3F3SN@33958,4H9N2@91061,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA gnl|extdb|FAM1079-i1-1.1_001277 797515.HMPREF9103_00439 0.0 1541.2 Lactobacillaceae secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TPEY@1239,3F4DH@33958,4HA22@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane gnl|extdb|FAM1079-i1-1.1_001278 797515.HMPREF9103_00440 5.4e-98 363.6 Lactobacillaceae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1V1D5@1239,3F40M@33958,4HFX9@91061,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase gnl|extdb|FAM1079-i1-1.1_001279 797515.HMPREF9103_00441 2.8e-64 251.9 Lactobacillaceae comFC ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 1V73S@1239,3F714@33958,4HJ6R@91061,COG1040@1,COG1040@2 NA|NA|NA S Competence protein gnl|extdb|FAM1079-i1-1.1_001280 797515.HMPREF9103_00443 1.4e-173 615.9 Lactobacillaceae comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K02240 M00429 ko00000,ko00002,ko02044 3.A.11.1 Bacteria 1TPZE@1239,3F3TQ@33958,4HB00@91061,COG4098@1,COG4098@2 NA|NA|NA L Helicase C-terminal domain protein gnl|extdb|FAM1079-i1-1.1_001281 797515.HMPREF9103_00444 1.5e-102 379.0 Lactobacillaceae yvyE 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1V6MQ@1239,3F3SQ@33958,4HBIT@91061,COG1739@1,COG1739@2 NA|NA|NA S YigZ family gnl|extdb|FAM1079-i1-1.1_001282 1423743.JCM14108_1552 8.9e-193 679.5 Lactobacillaceae tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 1TP9V@1239,3F4JV@33958,4H9KT@91061,COG0472@1,COG0472@2 NA|NA|NA M transferase gnl|extdb|FAM1079-i1-1.1_001283 797515.HMPREF9103_00446 3.7e-49 201.1 Lactobacillaceae lrgA GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0008565,GO:0009056,GO:0009057,GO:0009253,GO:0015031,GO:0015833,GO:0016020,GO:0030203,GO:0033036,GO:0042886,GO:0043170,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 ko:K05338,ko:K06518 ko02020,map02020 ko00000,ko00001,ko02000 1.E.14.1,1.E.14.2 Bacteria 1VIGA@1239,3F6PC@33958,4HN5Z@91061,COG1380@1,COG1380@2 NA|NA|NA S LrgA family gnl|extdb|FAM1079-i1-1.1_001284 797515.HMPREF9103_00447 1.9e-122 445.3 Lactobacillaceae lrgB ko:K05339 ko02020,map02020 ko00000,ko00001 Bacteria 1TRGN@1239,3F4A8@33958,4HE2Y@91061,COG1346@1,COG1346@2 NA|NA|NA M LrgB-like family gnl|extdb|FAM1079-i1-1.1_001285 797515.HMPREF9103_00448 0.0 1159.4 Lactobacillaceae ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 Bacteria 1TQE1@1239,3F44Y@33958,4HAZH@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid gnl|extdb|FAM1079-i1-1.1_001286 797515.HMPREF9103_00449 3.8e-293 1013.4 Lactobacillaceae groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1TP1T@1239,3F3MM@33958,4HA38@91061,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions gnl|extdb|FAM1079-i1-1.1_001288 797515.HMPREF9103_00451 5.7e-112 410.2 Lactobacillaceae rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,3F40G@33958,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state gnl|extdb|FAM1079-i1-1.1_001289 797515.HMPREF9103_00452 0.0 1162.9 Lactobacillaceae uup ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001290 797515.HMPREF9103_02318 4e-195 687.2 Lactobacillaceae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TQDR@1239,3F4AX@33958,4HANB@91061,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction gnl|extdb|FAM1079-i1-1.1_001291 797515.HMPREF9103_02317 2e-108 398.3 Lactobacillaceae rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,3F522@33958,4HIKU@91061,COG0454@1,COG0456@2 NA|NA|NA K Ribosomal-protein-alanine acetyltransferase gnl|extdb|FAM1079-i1-1.1_001292 797515.HMPREF9103_02316 1.5e-127 462.2 Lactobacillaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,3F3WV@33958,4HHD7@91061,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ gnl|extdb|FAM1079-i1-1.1_001294 797515.HMPREF9103_02314 9.9e-163 579.3 Lactobacillaceae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1TP6U@1239,3F4AI@33958,4HAH8@91061,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA gnl|extdb|FAM1079-i1-1.1_001295 797515.HMPREF9103_02313 2e-55 221.5 Lactobacillaceae yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1VA1F@1239,3F864@33958,4HKND@91061,COG4467@1,COG4467@2 NA|NA|NA L Involved in initiation control of chromosome replication gnl|extdb|FAM1079-i1-1.1_001296 797515.HMPREF9103_02312 1.3e-182 645.6 Lactobacillaceae holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRVS@1239,3F50D@33958,4HA3T@91061,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III gnl|extdb|FAM1079-i1-1.1_001297 797515.HMPREF9103_02311 5.3e-53 213.4 Lactobacillaceae yaaQ Bacteria 1V6NI@1239,3F6VW@33958,4HIHA@91061,COG3870@1,COG3870@2 NA|NA|NA S Cyclic-di-AMP receptor gnl|extdb|FAM1079-i1-1.1_001298 797515.HMPREF9103_02310 2.9e-111 407.9 Lactobacillaceae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02535 Bacteria 1V1HE@1239,3F4JR@33958,4HGWR@91061,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis gnl|extdb|FAM1079-i1-1.1_001299 525318.HMPREF0497_2822 4.5e-34 150.2 Lactobacillaceae yaaL Bacteria 1VM3Z@1239,2EHEM@1,33B6J@2,3F844@33958,4HR3I@91061 NA|NA|NA S Protein of unknown function (DUF2508) gnl|extdb|FAM1079-i1-1.1_001300 1423743.JCM14108_1532 7.1e-104 383.3 Lactobacillaceae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TR87@1239,3F4JQ@33958,4HAZR@91061,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO gnl|extdb|FAM1079-i1-1.1_001301 797515.HMPREF9103_02307 1.7e-48 198.4 Lactobacillaceae yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,3F7F3@33958,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection gnl|extdb|FAM1079-i1-1.1_001302 797515.HMPREF9103_02306 0.0 1106.7 Lactobacillaceae dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPS9@1239,3F3P2@33958,4HAUE@91061,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity gnl|extdb|FAM1079-i1-1.1_001304 797515.HMPREF9103_02305 1.5e-80 305.4 Lactobacillaceae tadA 3.5.4.33 ko:K11991 R10223 RC00477 ko00000,ko01000,ko03016 Bacteria 1V3HZ@1239,3F6IS@33958,4HH7S@91061,COG0590@1,COG0590@2 NA|NA|NA F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) gnl|extdb|FAM1079-i1-1.1_001305 797515.HMPREF9103_02304 2.6e-109 401.4 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V1BG@1239,3F4NU@33958,4HHCA@91061,COG2813@1,COG2813@2 NA|NA|NA J Methyltransferase gnl|extdb|FAM1079-i1-1.1_001306 1071400.LBUCD034_1508 9.5e-33 145.6 Lactobacillaceae nrdH GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009 ko:K06191 ko00000 Bacteria 1VEFX@1239,3F874@33958,4HNUX@91061,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin gnl|extdb|FAM1079-i1-1.1_001307 797515.HMPREF9103_02302 0.0 1448.7 Lactobacillaceae nrdE 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides gnl|extdb|FAM1079-i1-1.1_001308 797515.HMPREF9103_02301 2.5e-188 664.5 Lactobacillaceae nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,3F3P1@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides gnl|extdb|FAM1079-i1-1.1_001309 797515.HMPREF9103_02300 8e-177 626.3 Lactobacillaceae ldhD3 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_001310 797515.HMPREF9103_02299 5e-284 983.0 Lactobacillaceae galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPBN@1239,3F4D8@33958,4HAYJ@91061,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase gnl|extdb|FAM1079-i1-1.1_001311 797515.HMPREF9103_02298 2.1e-193 681.4 Lactobacillaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,3F3YF@33958,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family gnl|extdb|FAM1079-i1-1.1_001312 797515.HMPREF9103_02297 3.8e-226 790.4 Lactobacillaceae galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPD0@1239,3F3Q9@33958,4HARP@91061,COG0153@1,COG0153@2 NA|NA|NA F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) gnl|extdb|FAM1079-i1-1.1_001313 797515.HMPREF9103_02296 1.8e-176 625.2 Lactobacillaceae MA20_14895 Bacteria 1TQYA@1239,3F4TY@33958,4HCCP@91061,COG2855@1,COG2855@2 NA|NA|NA S Conserved hypothetical protein 698 gnl|extdb|FAM1079-i1-1.1_001315 797515.HMPREF9103_02294 3.5e-106 391.0 Lactobacillaceae Bacteria 1U6D0@1239,29PBA@1,30A9H@2,3F7MV@33958,4IG4S@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001316 797515.HMPREF9103_00967 0.0 1656.0 Lactobacillaceae mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 iYO844.BG12900 Bacteria 1TQI2@1239,3F3PY@33958,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2 NA|NA|NA S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms gnl|extdb|FAM1079-i1-1.1_001317 797515.HMPREF9103_00965 9.8e-48 196.1 Lactobacillaceae rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6EI@1239,3F6YA@33958,4HIGQ@91061,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation gnl|extdb|FAM1079-i1-1.1_001318 797515.HMPREF9103_00964 2e-86 325.1 Lactobacillaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JJ@1239,3F4S4@33958,4HH0N@91061,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors gnl|extdb|FAM1079-i1-1.1_001319 797515.HMPREF9103_00963 5.1e-122 443.7 Lactobacillaceae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPTS@1239,3F3VQ@33958,4HAK4@91061,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release gnl|extdb|FAM1079-i1-1.1_001320 797515.HMPREF9103_00962 8.1e-70 269.6 Lactobacillaceae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1BS@1239,3F64I@33958,4HFQ0@91061,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors gnl|extdb|FAM1079-i1-1.1_001322 797515.HMPREF9103_00960 5.2e-101 373.6 Lactobacillaceae nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1TR3P@1239,3F55W@33958,4HAJA@91061,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination gnl|extdb|FAM1079-i1-1.1_001323 1071400.LBUCD034_1522 1.2e-16 91.7 Lactobacillaceae secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VK48@1239,3F86Y@33958,4HR1W@91061,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation gnl|extdb|FAM1079-i1-1.1_001324 525318.HMPREF0497_2847 4.1e-21 106.3 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VFTQ@1239,3F83F@33958,4HR5Q@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family gnl|extdb|FAM1079-i1-1.1_001325 797515.HMPREF9103_00958 8.2e-99 366.3 Lactobacillaceae sigH ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Bacteria 1VG7U@1239,3F8D5@33958,4HNKD@91061,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family gnl|extdb|FAM1079-i1-1.1_001326 797515.HMPREF9103_00957 2.9e-96 357.8 Lactobacillaceae yacP ko:K06962 ko00000 Bacteria 1V9XR@1239,3F5KC@33958,4HFW4@91061,COG3688@1,COG3688@2 NA|NA|NA S YacP-like NYN domain gnl|extdb|FAM1079-i1-1.1_001327 797515.HMPREF9103_00956 5.1e-139 500.4 Lactobacillaceae rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K12952 ko00000,ko01000,ko03009 3.A.3.23 Bacteria 1TP9G@1239,3F3TD@33958,4HBBI@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gnl|extdb|FAM1079-i1-1.1_001328 797515.HMPREF9103_00955 2.9e-72 277.7 Lactobacillaceae mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K11145 ko00000,ko01000,ko03009 Bacteria 1VA5V@1239,3F6HS@33958,4HIM3@91061,COG1939@1,COG1939@2 NA|NA|NA J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) gnl|extdb|FAM1079-i1-1.1_001329 797515.HMPREF9103_00954 5.8e-274 949.5 Lactobacillaceae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1TP9D@1239,3F4K7@33958,4HA6D@91061,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family gnl|extdb|FAM1079-i1-1.1_001330 797515.HMPREF9103_00953 1.1e-278 965.3 Lactobacillaceae gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iSB619.SA_RS02860 Bacteria 1TPJC@1239,3F3PR@33958,4HAKH@91061,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gnl|extdb|FAM1079-i1-1.1_001331 797515.HMPREF9103_00952 2.4e-196 691.4 Lactobacillaceae yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TP0P@1239,3F46T@33958,4H9NQ@91061,COG4956@1,COG4956@2 NA|NA|NA S domain protein gnl|extdb|FAM1079-i1-1.1_001332 525318.HMPREF0497_2855 1.6e-236 825.1 Lactobacillaceae radA ko:K04485 ko00000,ko03400 Bacteria 1TQ7Y@1239,3F3W8@33958,4H9YC@91061,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function gnl|extdb|FAM1079-i1-1.1_001334 797515.HMPREF9103_00949 8.9e-127 459.5 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,3F43N@33958,4HFQ7@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate gnl|extdb|FAM1079-i1-1.1_001336 797515.HMPREF9103_00947 2e-126 458.4 Lactobacillaceae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1VU8J@1239,3FB96@33958,4HV7Z@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gnl|extdb|FAM1079-i1-1.1_001337 797515.HMPREF9103_00946 3.1e-162 577.8 Lactobacillaceae mleP2 ko:K07088 ko00000 Bacteria 1UY4N@1239,3FCFH@33958,4HB48@91061,COG0679@1,COG0679@2 NA|NA|NA S Transporter, auxin efflux carrier (AEC) family protein gnl|extdb|FAM1079-i1-1.1_001338 797515.HMPREF9103_00945 4.2e-190 670.6 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein gnl|extdb|FAM1079-i1-1.1_001339 1114972.AUAW01000027_gene720 1.3e-08 64.3 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_001273 797515.HMPREF9103_00435 2.4e-254 884.4 Lactobacillaceae phoR 2.7.13.3 ko:K07636,ko:K07652 ko02020,map02020 M00434,M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F3W2@33958,4HB1B@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM1079-i1-1.1_001287 797515.HMPREF9103_00450 1.8e-50 204.9 Lactobacillaceae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1V9ZM@1239,3F7CZ@33958,4HKEK@91061,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter gnl|extdb|FAM1079-i1-1.1_001321 797515.HMPREF9103_00961 3.6e-165 587.4 Lactobacillaceae Bacteria 1V910@1239,3F4RX@33958,4HF90@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) gnl|extdb|FAM1079-i1-1.1_001333 797515.HMPREF9103_00950 3.8e-96 357.5 Lactobacillaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V6HX@1239,3FB45@33958,4HIZ3@91061,COG0756@1,COG0756@2 NA|NA|NA F dUTPase gnl|extdb|FAM1079-i1-1.1_001335 797515.HMPREF9103_00948 8e-257 892.5 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F49B@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family gnl|extdb|FAM1079-i1-1.1_001340 575594.ACOH01000016_gene1565 1e-10 71.2 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_001341 797515.HMPREF9103_01177 1.2e-173 615.9 Lactobacillaceae Bacteria 1V08V@1239,3F5QM@33958,4IRX9@91061,COG3594@1,COG3594@2 NA|NA|NA I Acyltransferase gnl|extdb|FAM1079-i1-1.1_001342 797515.HMPREF9103_01176 1.7e-184 651.7 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase gnl|extdb|FAM1079-i1-1.1_001343 797515.HMPREF9103_01175 0.0 1683.3 Lactobacillaceae leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TP0Y@1239,3F46M@33958,4HAG1@91061,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family gnl|extdb|FAM1079-i1-1.1_001344 797515.HMPREF9103_01173 5.6e-91 340.5 Lactobacillaceae bcrC 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VF2U@1239,3F5CM@33958,4HNXR@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues gnl|extdb|FAM1079-i1-1.1_001345 797515.HMPREF9103_01172 6.8e-104 383.3 Lactobacillaceae ytqB Bacteria 1V6VU@1239,3FBTH@33958,4ISFT@91061,COG2519@1,COG2519@2 NA|NA|NA J Putative rRNA methylase gnl|extdb|FAM1079-i1-1.1_001346 797515.HMPREF9103_01171 9.2e-262 909.1 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001347 797515.HMPREF9103_01170 1.2e-216 758.8 Lactobacillaceae metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCV@1239,3F3T0@33958,4HB33@91061,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme gnl|extdb|FAM1079-i1-1.1_001349 797515.HMPREF9103_01168 2e-58 231.5 Lactobacillaceae Bacteria 1U65G@1239,29P5J@1,30A3R@2,3F743@33958,4IFVB@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001350 797515.HMPREF9103_01167 3.3e-161 574.3 Lactobacillaceae ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F4B8@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein gnl|extdb|FAM1079-i1-1.1_001351 797515.HMPREF9103_01166 1.8e-243 848.2 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM1079-i1-1.1_001352 797515.HMPREF9103_01165 4.9e-107 393.7 Lactobacillaceae pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 ko:K16788 ko00000,ko02000 2.A.88.5 iSB619.SA_RS09955 Bacteria 1V1CY@1239,3F41F@33958,4HFRS@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family gnl|extdb|FAM1079-i1-1.1_001353 797515.HMPREF9103_01164 9.6e-64 249.2 Lactobacillaceae Bacteria 1U5TW@1239,29NY1@1,309W5@2,3F6HX@33958,4IFHW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001354 797515.HMPREF9103_01163 3.4e-68 264.2 Lactobacillaceae asp2 Bacteria 1VJRA@1239,3F692@33958,4HXJN@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function gnl|extdb|FAM1079-i1-1.1_001355 797515.HMPREF9103_01162 2.7e-73 281.2 Lactobacillaceae asp Bacteria 1V8BY@1239,3FB57@33958,4HK2V@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function gnl|extdb|FAM1079-i1-1.1_001356 797515.HMPREF9103_01161 9.2e-23 112.1 Lactobacillaceae Bacteria 1U7UU@1239,2BMQC@1,32G9Q@2,3FA7D@33958,4IHS9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001357 797515.HMPREF9103_01160 4.6e-89 334.0 Lactobacillaceae Bacteria 1UJ8J@1239,2DRZ8@1,33DT5@2,3FBPW@33958,4HSYX@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001358 797515.HMPREF9103_01159 9.1e-21 105.9 Lactobacillaceae Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein gnl|extdb|FAM1079-i1-1.1_001359 797515.HMPREF9103_01157 2.7e-82 311.2 Lactobacillaceae Bacteria 1V6TR@1239,3F66M@33958,4HXA8@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001360 797515.HMPREF9103_01156 8.4e-156 556.2 Lactobacillaceae licD ko:K07271 ko00000,ko01000 Bacteria 1VBSV@1239,3FBFN@33958,4IQ3Z@91061,COG3475@1,COG3475@2 NA|NA|NA M LicD family gnl|extdb|FAM1079-i1-1.1_001361 797515.HMPREF9103_01155 2.1e-51 208.0 Lactobacillaceae XK27_08430 Bacteria 1VIJK@1239,2ED3T@1,3370N@2,3F765@33958,4HPGM@91061 NA|NA|NA S Staphylococcal protein of unknown function (DUF960) gnl|extdb|FAM1079-i1-1.1_001364 797515.HMPREF9103_01152 1.9e-52 211.5 Lactobacillaceae Bacteria 1VX4A@1239,2C26E@1,3424N@2,3F70Q@33958,4HXT9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001365 797515.HMPREF9103_01891 5.6e-200 703.4 Lactobacillaceae tagH 3.6.3.38,3.6.3.40 ko:K09689,ko:K09693 ko02010,map02010 M00249,M00251 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101,3.A.1.104 Bacteria 1TQKK@1239,3F4V6@33958,4HC6N@91061,COG1134@1,COG1134@2 NA|NA|NA GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_001366 797515.HMPREF9103_01890 9.8e-141 506.1 Lactobacillaceae ko:K02395 ko00000,ko02035 Bacteria 1UYRM@1239,3F5YS@33958,4HAU6@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gnl|extdb|FAM1079-i1-1.1_001367 797515.HMPREF9103_01889 3.1e-254 884.0 Lactobacillaceae ko:K02395 ko00000,ko02035 Bacteria 1UYRM@1239,3FC1X@33958,4HAU6@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gnl|extdb|FAM1079-i1-1.1_001368 797515.HMPREF9103_01790 0.0 1179.5 Lactobacillaceae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 1TPGU@1239,3F467@33958,4H9R4@91061,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gnl|extdb|FAM1079-i1-1.1_001369 797515.HMPREF9103_01791 8.4e-254 882.5 Lactobacillaceae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1TP1X@1239,3F3W5@33958,4HB16@91061,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gnl|extdb|FAM1079-i1-1.1_001370 525318.HMPREF0497_2751 3.7e-134 484.6 Lactobacillaceae ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 1TSIV@1239,3F41C@33958,4HD8Y@91061,COG4856@1,COG4856@2 NA|NA|NA S YbbR-like protein gnl|extdb|FAM1079-i1-1.1_001371 797515.HMPREF9103_01793 9.5e-147 526.2 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 1TPRW@1239,3F4N3@33958,4H9XZ@91061,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria gnl|extdb|FAM1079-i1-1.1_001372 797515.HMPREF9103_01794 1.7e-117 428.7 Lactobacillaceae Bacteria 1VEKF@1239,3FBN5@33958,4IR9Q@91061,COG4330@1,COG4330@2 NA|NA|NA S Protein of unknown function (DUF1361) gnl|extdb|FAM1079-i1-1.1_001373 797515.HMPREF9103_01795 0.0 1304.3 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter gnl|extdb|FAM1079-i1-1.1_001374 797515.HMPREF9103_01796 3.2e-172 610.9 Lactobacillaceae murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP3W@1239,3F40T@33958,4HAD8@91061,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation gnl|extdb|FAM1079-i1-1.1_001375 797515.HMPREF9103_01797 2.6e-97 361.3 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1V57H@1239,3F42Z@33958,4HI1V@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III gnl|extdb|FAM1079-i1-1.1_001376 797515.HMPREF9103_01799 4e-87 327.4 Lactobacillaceae Bacteria 1V22A@1239,3F7BU@33958,4ITA6@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_001377 797515.HMPREF9103_01800 1.1e-78 299.3 Lactobacillaceae ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 1V6CV@1239,3F3MR@33958,4HIIF@91061,COG0802@1,COG0802@2 NA|NA|NA O Hydrolase, P-loop family gnl|extdb|FAM1079-i1-1.1_001378 797515.HMPREF9103_01802 1e-179 636.0 Lactobacillaceae pta 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iSB619.SA_RS03155 Bacteria 1TPQ0@1239,3F3MW@33958,4H9VH@91061,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase gnl|extdb|FAM1079-i1-1.1_001379 797515.HMPREF9103_01803 5.5e-132 476.9 Lactobacillaceae ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSN@1239,3F3W0@33958,4HBTR@91061,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gnl|extdb|FAM1079-i1-1.1_001380 525318.HMPREF0497_2761 5.3e-85 320.5 Lactobacillaceae yxjI ko:K21429 ko00000,ko01002 Bacteria 1V8EY@1239,3F698@33958,4HMMS@91061,COG4894@1,COG4894@2 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001381 797515.HMPREF9103_01805 8.7e-81 306.2 Lactobacillaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,3F65B@33958,4HGZX@91061,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA gnl|extdb|FAM1079-i1-1.1_001382 797515.HMPREF9103_01806 0.0 1459.9 Lactobacillaceae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQ1G@1239,3F4EC@33958,4HBBH@91061,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs gnl|extdb|FAM1079-i1-1.1_001384 525318.HMPREF0497_2765 4.8e-32 143.3 Lactobacillaceae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEQR@1239,3F7IQ@33958,4HNKC@91061,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase gnl|extdb|FAM1079-i1-1.1_001385 797515.HMPREF9103_01809 6.8e-284 982.6 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F3MU@33958,4HD2H@91061,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P chloride gnl|extdb|FAM1079-i1-1.1_001386 797515.HMPREF9103_01810 8.4e-251 873.2 Lactobacillaceae Bacteria 1U6KA@1239,2A6YE@1,30VTD@2,3F836@33958,4IGD3@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001387 797515.HMPREF9103_01886 9.4e-250 869.0 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1TP2S@1239,3F3JP@33958,4HAKI@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis gnl|extdb|FAM1079-i1-1.1_001388 797515.HMPREF9103_01885 4.1e-141 507.3 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009758,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016854,GO:0016857,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.1.3.39,5.3.1.1,5.3.1.33 ko:K00927,ko:K01803,ko:K20905,ko:K21910 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265,iJN746.PP_4715 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) gnl|extdb|FAM1079-i1-1.1_001389 797515.HMPREF9103_01884 9.3e-228 795.8 Lactobacillaceae pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS04145 Bacteria 1TP3H@1239,3F3SC@33958,4H9R3@91061,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family gnl|extdb|FAM1079-i1-1.1_001390 797515.HMPREF9103_01883 2.9e-190 671.0 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F3JS@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gnl|extdb|FAM1079-i1-1.1_001392 1071400.LBUCD034_0901 5.2e-151 540.8 Lactobacillaceae Bacteria 1TQXU@1239,3FBIN@33958,4IQRV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001393 525318.HMPREF0497_2773 5.3e-151 540.4 Lactobacillaceae ykcA Bacteria 1UYDH@1239,3F4VB@33958,4HCYN@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gnl|extdb|FAM1079-i1-1.1_001394 797515.HMPREF9103_00413 2.2e-111 408.3 Lactobacillaceae clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQ91@1239,3F3M0@33958,4HA8J@91061,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins gnl|extdb|FAM1079-i1-1.1_001396 797515.HMPREF9103_00415 4.2e-167 594.0 Lactobacillaceae whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 ko:K09762 ko00000 Bacteria 1TP2X@1239,3F4AB@33958,4HB4H@91061,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation gnl|extdb|FAM1079-i1-1.1_001397 797515.HMPREF9103_00416 4.1e-189 667.2 Lactobacillaceae ybhK Bacteria 1TPNV@1239,3F4D5@33958,4HA0Z@91061,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions gnl|extdb|FAM1079-i1-1.1_001398 797515.HMPREF9103_00417 3e-167 594.3 Lactobacillaceae rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1TPS4@1239,3F4NY@33958,4H9KM@91061,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities gnl|extdb|FAM1079-i1-1.1_001399 797515.HMPREF9103_00418 0.0 1900.2 Lactobacillaceae uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPIJ@1239,3F4TZ@33958,4HAW9@91061,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate gnl|extdb|FAM1079-i1-1.1_001400 797515.HMPREF9103_00419 0.0 1297.7 Lactobacillaceae uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,3F3XM@33958,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage gnl|extdb|FAM1079-i1-1.1_001401 797515.HMPREF9103_00421 1.9e-118 431.8 Lactobacillaceae yfbR ko:K07023 ko00000 Bacteria 1TSDU@1239,3F4RZ@33958,4HA8H@91061,COG1896@1,COG1896@2 NA|NA|NA S HD containing hydrolase-like enzyme gnl|extdb|FAM1079-i1-1.1_001402 797515.HMPREF9103_00422 1e-173 615.9 Lactobacillaceae trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F411@33958,4HA4N@91061,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family gnl|extdb|FAM1079-i1-1.1_001403 797515.HMPREF9103_00423 1.2e-166 592.4 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase gnl|extdb|FAM1079-i1-1.1_001404 797515.HMPREF9103_00424 9e-184 649.4 Lactobacillaceae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQ5P@1239,3F4C8@33958,4HAXW@91061,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase gnl|extdb|FAM1079-i1-1.1_001405 797515.HMPREF9103_00425 3.3e-155 554.3 Lactobacillaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,3F42N@33958,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins gnl|extdb|FAM1079-i1-1.1_001406 797515.HMPREF9103_00426 9.5e-189 666.0 Lactobacillaceae hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1TP5Z@1239,3F3Z3@33958,4HAXR@91061,COG1493@1,COG1493@2 NA|NA|NA F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion gnl|extdb|FAM1079-i1-1.1_001407 797515.HMPREF9103_00427 4.8e-44 183.7 Lactobacillaceae yvlD ko:K08972 ko00000 Bacteria 1VF4I@1239,3F7IN@33958,4HNXP@91061,COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV gnl|extdb|FAM1079-i1-1.1_001408 797515.HMPREF9103_00428 7.6e-52 209.5 Lactobacillaceae ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VKBQ@1239,3F7ZE@33958,4HQZ8@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain protein gnl|extdb|FAM1079-i1-1.1_001348 797515.HMPREF9103_01169 1.3e-108 399.1 Lactobacillaceae Bacteria 1U5T9@1239,29NXN@1,309VT@2,3F6G3@33958,4IFH6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001383 797515.HMPREF9103_01807 7.7e-140 503.1 Lactobacillaceae est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 1TQ7X@1239,3F5XW@33958,4HBE6@91061,COG1647@1,COG1647@2 NA|NA|NA S Serine aminopeptidase, S33 gnl|extdb|FAM1079-i1-1.1_001395 797515.HMPREF9103_00414 2e-197 694.9 Lactobacillaceae adhA 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TP5B@1239,3F599@33958,4HVD8@91061,COG1064@1,COG1064@2 NA|NA|NA C Zinc-binding alcohol dehydrogenase family protein gnl|extdb|FAM1079-i1-1.1_001409 220668.lp_0423 4.8e-83 315.1 Lactobacillaceae comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 Bacteria 1V77J@1239,3F3QF@33958,4HAX2@91061,COG2274@1,COG2274@2 NA|NA|NA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain gnl|extdb|FAM1079-i1-1.1_001410 797515.HMPREF9103_02044 1e-125 456.1 Bacilli Bacteria 1UJ7F@1239,4IT3K@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_001412 797515.HMPREF9103_00320 2.6e-135 488.0 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase gnl|extdb|FAM1079-i1-1.1_001413 797515.HMPREF9103_00321 1.2e-194 685.6 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_001414 797515.HMPREF9103_00322 2.9e-114 417.9 Lactobacillaceae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_001415 797515.HMPREF9103_00323 9.1e-153 546.2 Lactobacillaceae metQ_4 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1V0Z6@1239,3FC6K@33958,4HBBW@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family gnl|extdb|FAM1079-i1-1.1_001416 797515.HMPREF9103_00992 1.5e-29 136.3 Lactobacillaceae Bacteria 1VEKB@1239,3F7M7@33958,4HH0D@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_001417 797515.HMPREF9103_00324 6.6e-105 386.7 Lactobacillaceae Bacteria 1VEKB@1239,3F84P@33958,4HH0D@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_001418 1423743.JCM14108_2517 1.9e-48 199.1 Lactobacillaceae Bacteria 1V4IG@1239,2A9SW@1,30Z0H@2,3F72V@33958,4HHW5@91061 NA|NA|NA S HTH domain gnl|extdb|FAM1079-i1-1.1_001419 797515.HMPREF9103_00327 8.8e-265 919.1 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid gnl|extdb|FAM1079-i1-1.1_001420 797515.HMPREF9103_00328 2.7e-252 877.5 Lactobacillaceae gabT 2.6.1.19,5.1.1.21 ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1UJDB@1239,3FBCB@33958,4IT60@91061,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gnl|extdb|FAM1079-i1-1.1_001421 797515.HMPREF9103_00329 2e-130 471.9 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VR9G@1239,3F3TR@33958,4HV4W@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM1079-i1-1.1_001422 797515.HMPREF9103_00331 2.6e-206 724.5 Lactobacillaceae ko:K07552 ko00000,ko02000 2.A.1.2 Bacteria 1TR6I@1239,3F461@33958,4HUZD@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001423 1071400.LBUCD034_2425 1.8e-78 298.5 Lactobacillaceae 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1VETR@1239,3F6C3@33958,4HNTN@91061,COG3613@1,COG3613@2 NA|NA|NA F nucleoside 2-deoxyribosyltransferase gnl|extdb|FAM1079-i1-1.1_001425 797515.HMPREF9103_01970 8.3e-93 346.7 Lactobacillaceae Bacteria 1TT38@1239,3F6A4@33958,4HCE2@91061,COG3382@1,COG3382@2 NA|NA|NA S B3/4 domain gnl|extdb|FAM1079-i1-1.1_001426 797515.HMPREF9103_01969 1e-139 502.7 Lactobacillaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPPR@1239,3FCA5@33958,4HBW9@91061,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis gnl|extdb|FAM1079-i1-1.1_001427 797515.HMPREF9103_01968 1.8e-251 874.8 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids gnl|extdb|FAM1079-i1-1.1_001428 1423780.LOT_1776 5.8e-174 617.1 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family gnl|extdb|FAM1079-i1-1.1_001429 1423743.JCM14108_1801 2.7e-276 957.6 Lactobacillaceae epsA Bacteria 1UYVP@1239,3F3UB@33958,4HF6D@91061,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily gnl|extdb|FAM1079-i1-1.1_001430 797515.HMPREF9103_01963 2e-116 425.2 Lactobacillaceae phoU ko:K02039 ko00000 Bacteria 1URN3@1239,3F46W@33958,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake gnl|extdb|FAM1079-i1-1.1_001431 797515.HMPREF9103_01962 1.1e-144 519.2 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_001432 797515.HMPREF9103_01961 1.1e-144 519.2 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_001433 797515.HMPREF9103_01960 1.4e-156 558.9 Lactobacillaceae pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3F412@33958,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease protein PstA gnl|extdb|FAM1079-i1-1.1_001435 797515.HMPREF9103_01958 3.4e-150 537.7 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate gnl|extdb|FAM1079-i1-1.1_001436 525318.HMPREF0497_0251 8.4e-110 403.3 Lactobacillaceae Bacteria 1U5CR@1239,3F5KE@33958,4IF3Z@91061,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal gnl|extdb|FAM1079-i1-1.1_001437 797515.HMPREF9103_01955 9.6e-272 942.2 Lactobacillaceae gapN GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114 1.2.1.9 ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 M00308,M00633 R01058 RC00242 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM1079-i1-1.1_001438 525318.HMPREF0497_0216 1.1e-52 212.6 Lactobacillaceae Bacteria 1U8J1@1239,2BURI@1,32Q2P@2,3FB1F@33958,4IIH0@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001440 797515.HMPREF9103_01947 1.5e-141 508.8 Lactobacillaceae Bacteria 1VW0F@1239,2F4SR@1,33XFD@2,3F6TR@33958,4HWCG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001441 797515.HMPREF9103_01946 2.3e-198 698.0 Lactobacillaceae aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKZ@1239,3F4JH@33958,4HAKN@91061,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) gnl|extdb|FAM1079-i1-1.1_001442 797515.HMPREF9103_01945 7.9e-188 662.9 Lactobacillaceae aroF 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP61@1239,3F5B5@33958,4HB03@91061,COG2876@1,COG2876@2 NA|NA|NA E DAHP synthetase I family gnl|extdb|FAM1079-i1-1.1_001444 797515.HMPREF9103_01944 1.6e-277 961.4 Lactobacillaceae trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQAP@1239,3F4RG@33958,4HB31@91061,COG0147@1,COG0147@2 NA|NA|NA EH Anthranilate synthase component I, N terminal region gnl|extdb|FAM1079-i1-1.1_001445 797515.HMPREF9103_01943 1.4e-107 395.6 Lactobacillaceae trpG 2.4.2.18,2.6.1.85,4.1.3.27 ko:K01658,ko:K01664,ko:K13497 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073,R01716 RC00010,RC00440,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT9R@1239,3F4C7@33958,4H9XP@91061,COG0512@1,COG0512@2 NA|NA|NA EH Peptidase C26 gnl|extdb|FAM1079-i1-1.1_001446 797515.HMPREF9103_01942 6.7e-25 119.0 Lactobacillaceae Bacteria 1U6ND@1239,29PIW@1,30AH1@2,3F86W@33958,4IGFD@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001447 797515.HMPREF9103_01941 1.1e-101 375.9 Lactobacillaceae kptA ko:K07559 ko00000,ko01000,ko03016 Bacteria 1V49Y@1239,3F5JJ@33958,4HN5V@91061,COG1859@1,COG1859@2 NA|NA|NA H Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase gnl|extdb|FAM1079-i1-1.1_001448 797515.HMPREF9103_01940 4e-81 307.4 Lactobacillaceae Bacteria 1U635@1239,29P3U@1,30A21@2,3F6XG@33958,4IFSF@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001449 797515.HMPREF9103_01939 7.6e-104 383.3 Lactobacillaceae Bacteria 1UVSU@1239,3F5K9@33958,4IF3X@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family gnl|extdb|FAM1079-i1-1.1_001451 797515.HMPREF9103_01937 3.9e-254 883.6 Lactobacillaceae ko:K03292 ko00000 2.A.2 Bacteria 1TRA5@1239,3F3UZ@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_001452 1423780.LOT_1705 0.0 1219.9 Lactobacillaceae Bacteria 1UTPW@1239,28IGZ@1,2Z8IA@2,3F4GD@33958,4HDGC@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001453 797515.HMPREF9103_01934 0.0 1496.5 Lactobacillaceae ko:K09955 ko00000 Bacteria 1TRI1@1239,3F53F@33958,4HETR@91061,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 gnl|extdb|FAM1079-i1-1.1_001454 797515.HMPREF9103_01933 4.4e-139 500.7 Lactobacillaceae yisR Bacteria 1UYDC@1239,3F5NH@33958,4HAAA@91061,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001455 797515.HMPREF9103_01932 5e-110 403.7 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V2BJ@1239,3FBKZ@33958,4HGCB@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family gnl|extdb|FAM1079-i1-1.1_001457 797515.HMPREF9103_01930 0.0 1257.3 Lactobacillaceae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,3F454@33958,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gnl|extdb|FAM1079-i1-1.1_001458 797515.HMPREF9103_01929 1.2e-258 898.7 Lactobacillaceae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1TPJF@1239,3F3WA@33958,4HA06@91061,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 gnl|extdb|FAM1079-i1-1.1_001459 797515.HMPREF9103_01928 7.3e-119 433.3 Lactobacillaceae jag ko:K06346 ko00000 Bacteria 1V3IN@1239,3F5WG@33958,4HHHU@91061,COG1847@1,COG1847@2 NA|NA|NA S R3H domain protein gnl|extdb|FAM1079-i1-1.1_001461 797515.HMPREF9103_01926 6.8e-137 493.4 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TQ0J@1239,3F3SD@33958,4HB3J@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins gnl|extdb|FAM1079-i1-1.1_001462 797515.HMPREF9103_01925 1.8e-62 245.0 Lactobacillaceae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1VA78@1239,3F6GS@33958,4HKG6@91061,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme gnl|extdb|FAM1079-i1-1.1_001463 1071400.LBUCD034_2468 9.8e-14 81.6 Lactobacillaceae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK90@1239,3F81W@33958,4HR2Z@91061,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family gnl|extdb|FAM1079-i1-1.1_001464 797515.HMPREF9103_01924 1.6e-257 894.8 Lactobacillaceae dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1TPV7@1239,3F3YA@33958,4H9MW@91061,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids gnl|extdb|FAM1079-i1-1.1_001465 797515.HMPREF9103_01923 4.2e-206 723.8 Lactobacillaceae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQ7J@1239,3F3ZQ@33958,4H9TF@91061,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria gnl|extdb|FAM1079-i1-1.1_001467 797515.HMPREF9103_01921 7.3e-203 713.0 Lactobacillaceae recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TP9U@1239,3F3Q1@33958,4HA0W@91061,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP gnl|extdb|FAM1079-i1-1.1_001468 797515.HMPREF9103_01920 0.0 1276.5 Lactobacillaceae gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 1TQ0R@1239,3F48M@33958,4H9Y6@91061,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gnl|extdb|FAM1079-i1-1.1_001469 797515.HMPREF9103_01919 0.0 1476.8 Lactobacillaceae gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 1TP2Z@1239,3F3YM@33958,4HAHY@91061,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gnl|extdb|FAM1079-i1-1.1_001411 797515.HMPREF9103_02042 6.8e-31 139.4 Lactobacillaceae Bacteria 1U77M@1239,29PYF@1,30AWV@2,3F92W@33958,4IH2F@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001434 797515.HMPREF9103_01959 7.4e-161 573.2 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane gnl|extdb|FAM1079-i1-1.1_001466 797515.HMPREF9103_01922 6.1e-38 162.9 Lactobacillaceae yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 1VEJ2@1239,3F803@33958,4HNMC@91061,COG2501@1,COG2501@2 NA|NA|NA S S4 domain protein YaaA gnl|extdb|FAM1079-i1-1.1_001471 525318.HMPREF0497_2032 1.1e-219 769.2 Lactobacillaceae rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,3F41R@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family gnl|extdb|FAM1079-i1-1.1_001472 525318.HMPREF0497_2031 8.6e-179 632.9 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQAU@1239,3F447@33958,4H9WD@91061,COG1597@1,COG1597@2 NA|NA|NA G Lipid kinase gnl|extdb|FAM1079-i1-1.1_001473 797515.HMPREF9103_01054 1.5e-272 944.9 Lactobacillaceae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPG3@1239,3F44H@33958,4HAFB@91061,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gnl|extdb|FAM1079-i1-1.1_001474 797515.HMPREF9103_01053 4.8e-271 939.9 Lactobacillaceae gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1TP0C@1239,3F4BK@33958,4HBAZ@91061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gnl|extdb|FAM1079-i1-1.1_001475 797515.HMPREF9103_01052 6.2e-51 206.5 Lactobacillaceae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,3F7XB@33958,4HNNA@91061,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gnl|extdb|FAM1079-i1-1.1_001476 797515.HMPREF9103_01051 1.1e-206 725.7 Lactobacillaceae camS Bacteria 1TSYE@1239,3F3KI@33958,4HBI8@91061,COG4851@1,COG4851@2 NA|NA|NA S sex pheromone gnl|extdb|FAM1079-i1-1.1_001477 797515.HMPREF9103_01050 0.0 1333.2 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,3F43C@33958,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA gnl|extdb|FAM1079-i1-1.1_001478 797515.HMPREF9103_01049 3.5e-111 407.5 Lactobacillaceae lacA 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3F47V@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose O-acetyltransferase gnl|extdb|FAM1079-i1-1.1_001479 797515.HMPREF9103_01048 0.0 1451.8 Lactobacillaceae pcrA 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,3F400@33958,4HB12@91061,COG0210@1,COG0210@2 NA|NA|NA L ATP-dependent DNA helicase gnl|extdb|FAM1079-i1-1.1_001480 797515.HMPREF9103_01047 1.7e-215 755.0 Lactobacillaceae purK2 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) gnl|extdb|FAM1079-i1-1.1_001481 797515.HMPREF9103_01046 1.6e-97 362.1 Lactobacillaceae xpt GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko04147 iYO844.BSU22070 Bacteria 1V1DU@1239,3F49S@33958,4HFNW@91061,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis gnl|extdb|FAM1079-i1-1.1_001483 797515.HMPREF9103_01044 9.6e-35 152.5 Lactobacillaceae Bacteria 1U69S@1239,29P8R@1,30A6V@2,3F7E0@33958,4IG0X@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001484 797515.HMPREF9103_01043 1.5e-82 312.4 Lactobacillaceae Bacteria 1VB4T@1239,3F497@33958,4HMUC@91061,COG4684@1,COG4684@2 NA|NA|NA S ECF transporter, substrate-specific component gnl|extdb|FAM1079-i1-1.1_001485 1071400.LBUCD034_1766 1.8e-63 248.4 Lactobacillaceae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3MQ@1239,3F656@33958,4HH3B@91061,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family gnl|extdb|FAM1079-i1-1.1_001486 797515.HMPREF9103_01040 7.1e-77 293.1 Lactobacillaceae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3HX@1239,3F696@33958,4HG0I@91061,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly gnl|extdb|FAM1079-i1-1.1_001487 797515.HMPREF9103_01039 3.2e-152 544.3 Lactobacillaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,3F4KC@33958,4HCFI@91061,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs gnl|extdb|FAM1079-i1-1.1_001488 797515.HMPREF9103_01038 2.5e-141 508.1 Lactobacillaceae ecfT ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQ0E@1239,3F3UW@33958,4H9VT@91061,COG0619@1,COG0619@2 NA|NA|NA U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates gnl|extdb|FAM1079-i1-1.1_001489 797515.HMPREF9103_01037 5.4e-161 573.5 Lactobacillaceae ecfA GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363 3.6.3.55 ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00186,M00211,M00581,M00582 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4 Bacteria 1TPH8@1239,3F48E@33958,4HA7T@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates gnl|extdb|FAM1079-i1-1.1_001490 797515.HMPREF9103_01036 9.1e-150 536.2 Lactobacillaceae ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K16784,ko:K16786 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F3VD@33958,4H9R8@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates gnl|extdb|FAM1079-i1-1.1_001491 1423743.JCM14108_2710 3.6e-61 240.7 Lactobacillaceae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6JQ@1239,3F6GJ@33958,4HGX2@91061,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 gnl|extdb|FAM1079-i1-1.1_001492 797515.HMPREF9103_01034 5.3e-170 603.6 Lactobacillaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,3F3W6@33958,4H9R1@91061,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM1079-i1-1.1_001493 797515.HMPREF9103_01033 4.4e-62 243.8 Lactobacillaceae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3IK@1239,3F67D@33958,4HH2T@91061,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome gnl|extdb|FAM1079-i1-1.1_001494 797515.HMPREF9103_01032 1.4e-57 228.8 Lactobacillaceae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JH@1239,3F6GN@33958,4HGX6@91061,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits gnl|extdb|FAM1079-i1-1.1_001495 387344.LVIS_1667 2.3e-14 83.6 Lactobacillaceae rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK4F@1239,3F8TC@33958,4HR2X@91061,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family gnl|extdb|FAM1079-i1-1.1_001496 1071400.LBUCD034_1777 1.1e-33 148.7 Lactobacillaceae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1V9ZK@1239,3F7CW@33958,4HKF4@91061,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex gnl|extdb|FAM1079-i1-1.1_001497 797515.HMPREF9103_01030 1.8e-124 451.8 Lactobacillaceae adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,3F3KB@33958,4HA89@91061,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism gnl|extdb|FAM1079-i1-1.1_001498 525318.HMPREF0497_2006 1.6e-228 798.5 Lactobacillaceae secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1TPHB@1239,3F4FV@33958,4HAWH@91061,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently gnl|extdb|FAM1079-i1-1.1_001499 797515.HMPREF9103_01027 1.4e-64 252.3 Lactobacillaceae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KE@1239,3F675@33958,4HFPW@91061,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA gnl|extdb|FAM1079-i1-1.1_001500 797515.HMPREF9103_01026 5.9e-25 119.4 Lactobacillaceae rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEG4@1239,3F7ZU@33958,4HNHF@91061,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 gnl|extdb|FAM1079-i1-1.1_001501 797515.HMPREF9103_01025 1.8e-84 318.5 Lactobacillaceae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1B1@1239,3F3VY@33958,4HFN4@91061,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body gnl|extdb|FAM1079-i1-1.1_001502 797515.HMPREF9103_01024 1.5e-56 225.3 Lactobacillaceae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DM@1239,3F6KN@33958,4HIGF@91061,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance gnl|extdb|FAM1079-i1-1.1_001503 797515.HMPREF9103_01023 1.2e-94 352.4 Lactobacillaceae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FC@1239,3F4G5@33958,4HFQD@91061,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center gnl|extdb|FAM1079-i1-1.1_001504 1071400.LBUCD034_1785 1.1e-65 255.8 Lactobacillaceae rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,3F64E@33958,4HH32@91061,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit gnl|extdb|FAM1079-i1-1.1_001505 1071400.LBUCD034_1786 3.3e-28 130.2 Bacilli rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,4HNKX@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site gnl|extdb|FAM1079-i1-1.1_001506 797515.HMPREF9103_01021 3.2e-95 354.4 Lactobacillaceae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPE0@1239,3F3Q7@33958,4HBAX@91061,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits gnl|extdb|FAM1079-i1-1.1_001507 797515.HMPREF9103_01020 2.8e-48 197.6 Lactobacillaceae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,3F6X5@33958,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit gnl|extdb|FAM1079-i1-1.1_001508 797515.HMPREF9103_01019 4.3e-59 233.8 Lactobacillaceae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3N0@1239,3F6GT@33958,4HGYR@91061,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome gnl|extdb|FAM1079-i1-1.1_001509 797515.HMPREF9103_01018 2.1e-39 167.9 Lactobacillaceae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YC@1239,3F7FX@33958,4HKDN@91061,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA gnl|extdb|FAM1079-i1-1.1_001510 797515.HMPREF9103_01017 1.6e-25 121.3 Lactobacillaceae rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEME@1239,3F82Z@33958,4HNUP@91061,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family gnl|extdb|FAM1079-i1-1.1_001511 797515.HMPREF9103_01016 2.4e-77 294.7 Lactobacillaceae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1AY@1239,3F653@33958,4HFPN@91061,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs gnl|extdb|FAM1079-i1-1.1_001512 797515.HMPREF9103_01015 6e-120 436.8 Lactobacillaceae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPCP@1239,3F3Q8@33958,4HAUR@91061,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation gnl|extdb|FAM1079-i1-1.1_001513 797515.HMPREF9103_01014 1.4e-54 218.8 Lactobacillaceae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6PU@1239,3F6K6@33958,4HIK2@91061,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome gnl|extdb|FAM1079-i1-1.1_001514 797515.HMPREF9103_01013 1.8e-46 191.4 Lactobacillaceae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6CX@1239,3F6XP@33958,4HIG0@91061,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA gnl|extdb|FAM1079-i1-1.1_001515 1423743.JCM14108_2734 2.2e-135 488.4 Lactobacillaceae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TP9X@1239,3F3XI@33958,4HAE8@91061,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity gnl|extdb|FAM1079-i1-1.1_001516 797515.HMPREF9103_01011 8.9e-44 182.6 Lactobacillaceae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA4W@1239,3F6Z2@33958,4HKCV@91061,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome gnl|extdb|FAM1079-i1-1.1_001517 797515.HMPREF9103_01010 1.9e-107 395.2 Lactobacillaceae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPGW@1239,3F3QD@33958,4HB01@91061,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel gnl|extdb|FAM1079-i1-1.1_001518 797515.HMPREF9103_01009 1.8e-113 415.2 Lactobacillaceae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPFT@1239,3F45I@33958,4HAEN@91061,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit gnl|extdb|FAM1079-i1-1.1_001519 525318.HMPREF0497_1985 9.7e-49 199.1 Lactobacillaceae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6C9@1239,3F6KC@33958,4HIKH@91061,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes gnl|extdb|FAM1079-i1-1.1_001520 797515.HMPREF9103_01006 0.0 1374.4 Lactobacillaceae fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPF9@1239,3F3JR@33958,4HAB8@91061,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome gnl|extdb|FAM1079-i1-1.1_001521 1423743.JCM14108_2742 1.2e-82 312.4 Lactobacillaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1GG@1239,3F3RX@33958,4H9PA@91061,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA gnl|extdb|FAM1079-i1-1.1_001522 1423743.JCM14108_2743 4.6e-70 270.4 Lactobacillaceae rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FJ@1239,3F64B@33958,4HFMZ@91061,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit gnl|extdb|FAM1079-i1-1.1_001523 797515.HMPREF9103_01003 1.4e-122 445.7 Lactobacillaceae pilD 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 1TQY4@1239,3FC6I@33958,4HPGZ@91061,COG1989@1,COG1989@2 NA|NA|NA NOU Type IV leader peptidase family gnl|extdb|FAM1079-i1-1.1_001524 797515.HMPREF9103_01002 0.0 2420.2 Lactobacillaceae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TNYT@1239,3F3KF@33958,4HA24@91061,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM1079-i1-1.1_001525 1071400.LBUCD034_1807 0.0 2272.7 Lactobacillaceae rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TP96@1239,3F4ET@33958,4H9PK@91061,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates gnl|extdb|FAM1079-i1-1.1_001526 797515.HMPREF9103_00999 0.0 1581.2 Lactobacillaceae clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE gnl|extdb|FAM1079-i1-1.1_001527 797515.HMPREF9103_00998 1.5e-77 295.4 Lactobacillaceae ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03708 ko00000,ko03000 Bacteria 1VAXT@1239,3F53E@33958,4HIFT@91061,COG4463@1,COG4463@2 NA|NA|NA K Belongs to the CtsR family gnl|extdb|FAM1079-i1-1.1_001536 797515.HMPREF9103_02978 2.7e-201 708.0 Lactobacillaceae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,3F3M6@33958,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) gnl|extdb|FAM1079-i1-1.1_001537 797515.HMPREF9103_02979 1.7e-116 425.2 Lactobacillaceae dak 2.7.1.74,2.7.1.76 ko:K00893,ko:K10353 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase gnl|extdb|FAM1079-i1-1.1_001538 797515.HMPREF9103_02980 3.9e-198 697.2 Lactobacillaceae yihT GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061595,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 4.1.2.40,4.1.2.57 ko:K01635,ko:K01671 ko00052,ko01100,ko02024,map00052,map01100,map02024 R01069,R10760 RC00438,RC00439 ko00000,ko00001,ko01000 Bacteria 1TQRR@1239,3F3UA@33958,4HBS9@91061,COG3684@1,COG3684@2 NA|NA|NA G Belongs to the aldolase LacD family gnl|extdb|FAM1079-i1-1.1_001539 797515.HMPREF9103_02981 4.3e-275 953.4 Lactobacillaceae lysP ko:K03293,ko:K11733 ko00000,ko02000 2.A.3.1,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid gnl|extdb|FAM1079-i1-1.1_001540 797515.HMPREF9103_02982 8.7e-87 326.2 Lactobacillaceae 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1VQDG@1239,3F7B4@33958,4HHTI@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_001541 525318.HMPREF0497_1971 1.3e-104 386.0 Lactobacillaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VY85@1239,3F4DD@33958,4HXM4@91061,COG0671@1,COG0671@2 NA|NA|NA I phosphatase gnl|extdb|FAM1079-i1-1.1_001542 797515.HMPREF9103_02984 1.8e-137 495.4 Lactobacillaceae yxaA ko:K07090 ko00000 Bacteria 1TPMA@1239,3F3T9@33958,4HESP@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM1079-i1-1.1_001543 797515.HMPREF9103_02985 7e-57 226.5 Lactobacillaceae ywjH Bacteria 1VAPQ@1239,3FCD9@33958,4HNDQ@91061,COG4272@1,COG4272@2 NA|NA|NA S Protein of unknown function (DUF1634) gnl|extdb|FAM1079-i1-1.1_001544 797515.HMPREF9103_02987 1.9e-151 542.0 Lactobacillaceae Bacteria 1VJU7@1239,3F6HR@33958,4HQ8U@91061,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin gnl|extdb|FAM1079-i1-1.1_001545 797515.HMPREF9103_02988 3.5e-93 347.8 Lactobacillaceae XK27_06920 Bacteria 1VD2S@1239,3FBMR@33958,4HN8T@91061,COG4709@1,COG4709@2 NA|NA|NA S Protein of unknown function (DUF1700) gnl|extdb|FAM1079-i1-1.1_001546 797515.HMPREF9103_02989 6.7e-53 213.0 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VACN@1239,3FCDA@33958,4HQIW@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001482 797515.HMPREF9103_01045 4.9e-102 377.1 Lactobacillaceae acmC 3.2.1.96 ko:K01227,ko:K02395 ko00511,map00511 ko00000,ko00001,ko01000,ko02035 Bacteria 1V7JY@1239,3F584@33958,4HIY4@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein gnl|extdb|FAM1079-i1-1.1_001548 1071400.LBUCD034_0640 2.2e-211 741.5 Lactobacillaceae Bacteria 1V3NJ@1239,3F4KD@33958,4HTUC@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM1079-i1-1.1_001549 797515.HMPREF9103_02210 5.4e-211 740.0 Lactobacillaceae uxuA 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP5F@1239,3F4UF@33958,4H9UR@91061,COG1312@1,COG1312@2 NA|NA|NA G Catalyzes the dehydration of D-mannonate gnl|extdb|FAM1079-i1-1.1_001550 797515.HMPREF9103_02211 7.3e-118 429.9 Lactobacillaceae kdgR Bacteria 1V3SB@1239,3F69H@33958,4HGG8@91061,COG1802@1,COG1802@2 NA|NA|NA K FCD domain gnl|extdb|FAM1079-i1-1.1_001551 797515.HMPREF9103_02212 4.6e-188 663.7 Lactobacillaceae kdgK 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRRY@1239,3F4X6@33958,4HBEE@91061,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase gnl|extdb|FAM1079-i1-1.1_001552 797515.HMPREF9103_02213 1e-72 279.3 Lactobacillaceae Bacteria 1U745@1239,2ATFC@1,31IYW@2,3F8Y4@33958,4IGYR@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001553 797515.HMPREF9103_02214 1.8e-40 171.4 Lactobacillaceae Bacteria 1U79F@1239,29Z15@1,30KYA@2,3F95H@33958,4IH4A@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001554 797515.HMPREF9103_02215 6.7e-156 556.6 Lactobacillaceae 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V639@1239,3FBJZ@33958,4IQY1@91061,COG2365@1,COG2365@2 NA|NA|NA T Pfam:Y_phosphatase3C gnl|extdb|FAM1079-i1-1.1_001555 797515.HMPREF9103_02216 1.2e-163 582.4 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F4B8@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein gnl|extdb|FAM1079-i1-1.1_001556 797515.HMPREF9103_02217 3.5e-239 833.9 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system gnl|extdb|FAM1079-i1-1.1_001557 797515.HMPREF9103_02218 3.9e-116 424.1 Lactobacillaceae Bacteria 1V3R8@1239,3F75F@33958,4HBEK@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_001558 797515.HMPREF9103_02219 5.9e-239 833.2 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system gnl|extdb|FAM1079-i1-1.1_001560 797515.HMPREF9103_02223 5.2e-148 530.4 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport gnl|extdb|FAM1079-i1-1.1_001561 797515.HMPREF9103_02225 1.7e-128 465.3 Lactobacillaceae Bacteria 1TRHF@1239,3F468@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM1079-i1-1.1_001562 525318.HMPREF0497_1139 3.2e-86 324.7 Lactobacillaceae magIII ko:K07457 ko00000 Bacteria 1V4SG@1239,3F62T@33958,4HI5U@91061,COG2231@1,COG2231@2 NA|NA|NA L Base excision DNA repair protein, HhH-GPD family gnl|extdb|FAM1079-i1-1.1_001563 797515.HMPREF9103_02228 1.2e-272 945.3 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid gnl|extdb|FAM1079-i1-1.1_001564 797515.HMPREF9103_02229 5.7e-250 869.8 Lactobacillaceae yjjP Bacteria 1TNZH@1239,3F4FR@33958,4HU4D@91061,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Putative threonine/serine exporter gnl|extdb|FAM1079-i1-1.1_001565 797515.HMPREF9103_02230 2.8e-79 301.2 Lactobacillaceae ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380 Bacteria 1V1DA@1239,3F70X@33958,4HFRA@91061,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin gnl|extdb|FAM1079-i1-1.1_001566 797515.HMPREF9103_02231 3.5e-227 793.9 Lactobacillaceae ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10830,iSB619.SA_RS08945 Bacteria 1TPH9@1239,3F4EB@33958,4H9PW@91061,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate gnl|extdb|FAM1079-i1-1.1_001567 797515.HMPREF9103_02232 2.7e-103 381.3 Lactobacillaceae ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950,iYO844.BSU23270 Bacteria 1V1EP@1239,3F6M0@33958,4HC7B@91061,COG0307@1,COG0307@2 NA|NA|NA H Riboflavin synthase gnl|extdb|FAM1079-i1-1.1_001568 797515.HMPREF9103_02233 2.3e-190 671.4 Lactobacillaceae ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K00082,ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iLJ478.TM1828 Bacteria 1TP4F@1239,3F4X5@33958,4HBNA@91061,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate gnl|extdb|FAM1079-i1-1.1_001570 797515.HMPREF9103_02236 7.9e-28 129.0 Lactobacillaceae copZ GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006875,GO:0008150,GO:0009987,GO:0019725,GO:0030001,GO:0030003,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 2.7.7.77 ko:K03752,ko:K07213,ko:K08364 ko00790,ko01100,ko04978,map00790,map01100,map04978 R11581 ko00000,ko00001,ko01000,ko02000 1.A.72.1 Bacteria 1VK5F@1239,3F8XB@33958,4IGXX@91061,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain gnl|extdb|FAM1079-i1-1.1_001571 797515.HMPREF9103_02237 1.1e-74 285.8 Lactobacillaceae Bacteria 1VA7Q@1239,3F7D0@33958,4HKGF@91061,COG3682@1,COG3682@2 NA|NA|NA K Copper transport repressor CopY TcrY gnl|extdb|FAM1079-i1-1.1_001572 797515.HMPREF9103_02240 8e-193 679.5 Lactobacillaceae ko:K19265 ko00000,ko01000 Bacteria 1TRS0@1239,3F414@33958,4HAZ2@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase family protein gnl|extdb|FAM1079-i1-1.1_001573 525318.HMPREF0497_1132 9.7e-36 156.4 Lactobacillaceae ko:K11686 ko00000,ko03036 Bacteria 1VF47@1239,3F7RP@33958,4HZAE@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM1079-i1-1.1_001574 797515.HMPREF9103_02242 1.3e-168 599.0 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3F3QR@33958,4HHVC@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein gnl|extdb|FAM1079-i1-1.1_001575 797515.HMPREF9103_02243 2.9e-102 378.3 Bacteria Bacteria COG0431@1,COG0431@2 NA|NA|NA S FMN reductase (NADPH) activity gnl|extdb|FAM1079-i1-1.1_001576 797515.HMPREF9103_02244 7.9e-61 239.6 Lactobacillaceae czrA ko:K21903,ko:K22043 ko00000,ko03000 Bacteria 1VA6G@1239,3F7DH@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator, ArsR family gnl|extdb|FAM1079-i1-1.1_001577 797515.HMPREF9103_02245 1.3e-89 335.9 Lactobacillaceae 2.5.1.105 ko:K04088,ko:K06897 ko00790,map00790 M00742 R10339 RC00121 ko00000,ko00001,ko00002,ko01000 Bacteria 1V9B6@1239,3F4M1@33958,4HJTJ@91061,COG0053@1,COG0053@2 NA|NA|NA P Cation efflux family gnl|extdb|FAM1079-i1-1.1_001578 797515.HMPREF9103_02247 8.9e-116 422.9 Lactobacillaceae Bacteria 1VB1Q@1239,2DS3U@1,32USA@2,3F531@33958,4IEZ8@91061 NA|NA|NA S Golgi phosphoprotein 3 (GPP34) gnl|extdb|FAM1079-i1-1.1_001580 797515.HMPREF9103_02249 3.3e-152 544.3 Lactobacillaceae Bacteria 1U7B9@1239,29PC0@1,30AZK@2,3F99I@33958,4IH69@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001581 797515.HMPREF9103_02251 1.8e-75 288.9 Lactobacillaceae ko:K19224,ko:K21471 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 1VG0Z@1239,3F50V@33958,4HBE9@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC P60 family protein gnl|extdb|FAM1079-i1-1.1_001583 797515.HMPREF9103_02254 2.6e-91 341.3 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1VVUW@1239,3F5KH@33958,4HW42@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase gnl|extdb|FAM1079-i1-1.1_001584 797515.HMPREF9103_02255 9.2e-113 412.9 Lactobacillaceae Bacteria 1U67H@1239,3F792@33958,4IFY0@91061,COG0300@1,COG0300@2 NA|NA|NA S short chain dehydrogenase gnl|extdb|FAM1079-i1-1.1_001585 797515.HMPREF9103_02256 9.3e-158 562.8 Lactobacillaceae arbZ Bacteria 1V2F4@1239,3F5FU@33958,4IF2T@91061,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases gnl|extdb|FAM1079-i1-1.1_001586 797515.HMPREF9103_02257 1.4e-178 632.1 Lactobacillaceae arbY GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 Bacteria 1UY8Y@1239,3F4YJ@33958,4HBAE@91061,COG1442@1,COG1442@2 NA|NA|NA M family 8 gnl|extdb|FAM1079-i1-1.1_001587 797515.HMPREF9103_02258 3e-147 527.7 Lactobacillaceae arbV 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1V6NX@1239,3FBFU@33958,4IQ5I@91061,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases gnl|extdb|FAM1079-i1-1.1_001588 797515.HMPREF9103_02260 3.8e-262 910.6 Lactobacillaceae lmrA 3.6.3.44 ko:K06147,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21 Bacteria 1TSY4@1239,3FC4S@33958,4HAJQ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_001589 797515.HMPREF9103_02261 4.6e-160 570.5 Lactobacillaceae arbx Bacteria 1UY4M@1239,3F4YZ@33958,4IEY6@91061,COG1442@1,COG1442@2 NA|NA|NA M Glycosyl transferase family 8 gnl|extdb|FAM1079-i1-1.1_001590 797515.HMPREF9103_02263 1e-130 472.6 Lactobacillaceae gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQFP@1239,3F3SK@33958,4HAW7@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gnl|extdb|FAM1079-i1-1.1_001592 797515.HMPREF9103_00523 3.1e-119 434.9 Lactobacillaceae Bacteria 1VM03@1239,2EIB1@1,33C2F@2,3F5MI@33958,4HS05@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001593 797515.HMPREF9103_00521 1.2e-247 862.1 Lactobacillaceae pbpX Bacteria 1V7PM@1239,3FBFP@33958,4HIHX@91061,COG1680@1,COG1680@2 NA|NA|NA V SH3-like domain gnl|extdb|FAM1079-i1-1.1_001594 797515.HMPREF9103_00520 5e-248 863.2 Lactobacillaceae dltD ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TSZU@1239,3F3WE@33958,4HC3H@91061,COG3966@1,COG3966@2 NA|NA|NA M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) gnl|extdb|FAM1079-i1-1.1_001595 797515.HMPREF9103_00519 8e-35 152.5 Lactobacillaceae dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VFQI@1239,3F7Q1@33958,4HNIH@91061,COG0236@1,COG0236@2 NA|NA|NA J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall gnl|extdb|FAM1079-i1-1.1_001596 797515.HMPREF9103_00518 2.5e-236 824.3 Lactobacillaceae dltB ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TP52@1239,3F4KK@33958,4HBQG@91061,COG1696@1,COG1696@2 NA|NA|NA M MBOAT, membrane-bound O-acyltransferase family gnl|extdb|FAM1079-i1-1.1_001597 797515.HMPREF9103_00517 1.7e-282 978.0 Lactobacillaceae dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPTH@1239,3F49R@33958,4HAHU@91061,COG1020@1,COG1020@2 NA|NA|NA H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall gnl|extdb|FAM1079-i1-1.1_001598 797515.HMPREF9103_00516 2.8e-17 93.6 Lactobacillaceae dltX Bacteria 1U6XZ@1239,2DKST@1,30APB@2,3F8PK@33958,4IGS5@91061 NA|NA|NA S D-Ala-teichoic acid biosynthesis protein gnl|extdb|FAM1079-i1-1.1_001599 797515.HMPREF9103_00515 7.2e-220 769.6 Lactobacillaceae pbpX2 ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1V0GX@1239,3F4TH@33958,4HCXH@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase gnl|extdb|FAM1079-i1-1.1_001600 797515.HMPREF9103_00514 5.6e-44 183.7 Lactobacillaceae Bacteria 1U6RX@1239,29PM4@1,30AJA@2,3F8DX@33958,4IGJE@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001601 797515.HMPREF9103_00513 4.4e-67 260.4 Lactobacillaceae yueI Bacteria 1V8ID@1239,3F7A5@33958,4HJTQ@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) gnl|extdb|FAM1079-i1-1.1_001602 797515.HMPREF9103_00512 3.6e-174 617.5 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1V2UJ@1239,3F52N@33958,4HG2A@91061,COG0604@1,COG0604@2 NA|NA|NA C alcohol dehydrogenase gnl|extdb|FAM1079-i1-1.1_001603 797515.HMPREF9103_00511 1.4e-53 215.3 Lactobacillaceae azlD Bacteria 1UF1S@1239,3F7GD@33958,4HQ7J@91061,COG4392@1,COG4392@2 NA|NA|NA S branched-chain amino acid gnl|extdb|FAM1079-i1-1.1_001604 797515.HMPREF9103_00510 1.3e-137 495.7 Lactobacillaceae azlC Bacteria 1V58A@1239,3FB4G@33958,4HI11@91061,COG1296@1,COG1296@2 NA|NA|NA E AzlC protein gnl|extdb|FAM1079-i1-1.1_001579 797515.HMPREF9103_02248 2.7e-151 541.2 Lactobacillaceae Bacteria 1U6E0@1239,29PC0@1,30AA7@2,3F7PG@33958,4IG5U@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001582 797515.HMPREF9103_02252 4e-116 424.1 Lactobacillaceae Bacteria 1VNYB@1239,2DRRS@1,33CS9@2,3F8RI@33958,4HRN3@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001591 797515.HMPREF9103_02264 4e-163 580.9 Lactobacillaceae Bacteria 1TSBK@1239,3F46E@33958,4HBYJ@91061,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter gnl|extdb|FAM1079-i1-1.1_001606 797515.HMPREF9103_01116 0.0 1374.8 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily gnl|extdb|FAM1079-i1-1.1_001607 797515.HMPREF9103_01115 2.5e-181 641.3 Lactobacillaceae mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1UY7Z@1239,3F3UR@33958,4HCG6@91061,COG0392@1,COG0392@2 NA|NA|NA I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms gnl|extdb|FAM1079-i1-1.1_001608 797515.HMPREF9103_01114 1.6e-196 691.8 Lactobacillaceae cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 ko:K13678 R10865 RC00005,RC00049 ko00000,ko01000,ko01003 GT4 Bacteria 1TPSS@1239,3F47X@33958,4HB9F@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein gnl|extdb|FAM1079-i1-1.1_001609 797515.HMPREF9103_01113 1.8e-220 771.5 Lactobacillaceae mgs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPTA@1239,3F4H5@33958,4HA41@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein gnl|extdb|FAM1079-i1-1.1_001610 797515.HMPREF9103_01112 0.0 1114.8 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) gnl|extdb|FAM1079-i1-1.1_001611 797515.HMPREF9103_01111 4.6e-39 166.8 Lactobacillaceae ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,3F6XQ@33958,4HKGA@91061,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein HPR gnl|extdb|FAM1079-i1-1.1_001612 797515.HMPREF9103_01110 4.2e-32 143.3 Lactobacillaceae Bacteria 1U4CC@1239,2EI19@1,33BSS@2,3F8QK@33958,4IGST@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001613 525318.HMPREF0497_2081 0.0 1347.4 Lactobacillaceae clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F3K9@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family gnl|extdb|FAM1079-i1-1.1_001614 797515.HMPREF9103_01108 3.4e-200 704.1 Lactobacillaceae Bacteria 1UHY3@1239,3FBRZ@33958,4ISAI@91061,COG4932@1,COG4932@2 NA|NA|NA M MucBP domain gnl|extdb|FAM1079-i1-1.1_001615 797515.HMPREF9103_01107 4.4e-261 906.7 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase gnl|extdb|FAM1079-i1-1.1_001616 797515.HMPREF9103_01106 2.6e-307 1060.4 Lactobacillaceae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1TPYT@1239,3F489@33958,4HADS@91061,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP gnl|extdb|FAM1079-i1-1.1_001617 797515.HMPREF9103_01105 0.0 1292.3 Lactobacillaceae 2.7.8.12 ko:K09809 ko00000,ko01000 Bacteria 1TP75@1239,3FC1J@33958,4H9Q1@91061,COG1887@1,COG1887@2 NA|NA|NA M glycerophosphotransferase gnl|extdb|FAM1079-i1-1.1_001618 797515.HMPREF9103_01104 4.6e-157 560.5 Lactobacillaceae Bacteria 1U5YP@1239,29P0U@1,309YY@2,3F6QD@33958,4IFMR@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001619 525318.HMPREF0497_2075 2.6e-73 281.2 Lactobacillaceae tagD 2.7.7.15,2.7.7.39 ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 M00090 R00856,R01890,R02590 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3KY@1239,3F65R@33958,4HGWZ@91061,COG0615@1,COG0615@2 NA|NA|NA IM Glycerol-3-phosphate cytidylyltransferase gnl|extdb|FAM1079-i1-1.1_001621 797515.HMPREF9103_01100 2.4e-106 391.3 Lactobacillaceae ygaC ko:K07586 ko00000 Bacteria 1TRX8@1239,3F48S@33958,4H9NM@91061,COG3557@1,COG3557@2 NA|NA|NA J Belongs to the UPF0374 family gnl|extdb|FAM1079-i1-1.1_001623 797515.HMPREF9103_01098 1.3e-78 298.9 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1V7AG@1239,3F6HY@33958,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin gnl|extdb|FAM1079-i1-1.1_001624 797515.HMPREF9103_01097 2.8e-152 544.7 Lactobacillaceae yihY ko:K07058 ko00000 Bacteria 1U7HM@1239,3F4TC@33958,4H9MJ@91061,COG1295@1,COG1295@2 NA|NA|NA S Belongs to the UPF0761 family gnl|extdb|FAM1079-i1-1.1_001626 797515.HMPREF9103_01095 7.9e-174 616.3 Lactobacillaceae csbB 2.4.1.83 ko:K00721,ko:K20534 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1UI5W@1239,3FBSD@33958,4ISEQ@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 gnl|extdb|FAM1079-i1-1.1_001627 797515.HMPREF9103_01094 1e-72 279.3 Lactobacillaceae gtcA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VESW@1239,3F4GH@33958,4HNK7@91061,COG2246@1,COG2246@2 NA|NA|NA S Teichoic acid glycosylation protein gnl|extdb|FAM1079-i1-1.1_001628 797515.HMPREF9103_01092 1.9e-288 997.7 Lactobacillaceae katA GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPPV@1239,3F5CW@33958,4H9XQ@91061,COG0753@1,COG0753@2 NA|NA|NA C Belongs to the catalase family gnl|extdb|FAM1079-i1-1.1_001630 797515.HMPREF9103_01089 1.1e-226 792.3 Lactobacillaceae yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 Bacteria 1TQ9R@1239,3F4K8@33958,4HANR@91061,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase gnl|extdb|FAM1079-i1-1.1_001631 797515.HMPREF9103_01088 2.8e-193 681.0 Lactobacillaceae mocA ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3F4EV@33958,4HCIG@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase gnl|extdb|FAM1079-i1-1.1_001632 797515.HMPREF9103_01087 4.4e-64 250.4 Lactobacillaceae Bacteria 1VNS7@1239,2EGZM@1,33ARR@2,3F83W@33958,4HSZW@91061 NA|NA|NA S Domain of unknown function (DUF4828) gnl|extdb|FAM1079-i1-1.1_001633 797515.HMPREF9103_01085 5.8e-143 513.5 Lactobacillaceae lys ko:K07273 ko00000 Bacteria 1V484@1239,3F4K0@33958,4HQWA@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 gnl|extdb|FAM1079-i1-1.1_001634 797515.HMPREF9103_01084 2.1e-149 535.0 Lactobacillaceae gntR Bacteria 1TR0N@1239,3F42G@33958,4HB9E@91061,COG1737@1,COG1737@2 NA|NA|NA K rpiR family gnl|extdb|FAM1079-i1-1.1_001635 797515.HMPREF9103_01083 3.1e-308 1063.5 Lactobacillaceae gntK 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family gnl|extdb|FAM1079-i1-1.1_001637 797515.HMPREF9103_01081 4.1e-131 474.2 Lactobacillaceae Bacteria 1U8KG@1239,29QSS@1,30BSM@2,3FB2Y@33958,4IIIF@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001638 797515.HMPREF9103_01080 1e-85 322.8 Lactobacillaceae bioY GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1V9T0@1239,3FBMX@33958,4HK0R@91061,COG1268@1,COG1268@2 NA|NA|NA S BioY family gnl|extdb|FAM1079-i1-1.1_001639 797515.HMPREF9103_01079 1.8e-189 668.3 Lactobacillaceae birA 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor gnl|extdb|FAM1079-i1-1.1_001640 797515.HMPREF9103_01078 7.5e-135 486.5 Lactobacillaceae fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPVD@1239,3F4AQ@33958,4H9YN@91061,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH gnl|extdb|FAM1079-i1-1.1_001641 797515.HMPREF9103_01077 2.4e-144 518.1 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,3F496@33958,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I alpha subunit gnl|extdb|FAM1079-i1-1.1_001642 797515.HMPREF9103_01076 1.7e-151 542.0 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F3T6@33958,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA gnl|extdb|FAM1079-i1-1.1_001643 797515.HMPREF9103_01075 1.5e-258 898.3 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit gnl|extdb|FAM1079-i1-1.1_001644 797515.HMPREF9103_01074 4.5e-73 280.4 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1VXBZ@1239,3F6TF@33958,4HXVK@91061,COG0764@1,COG0764@2 NA|NA|NA I FabA-like domain gnl|extdb|FAM1079-i1-1.1_001645 797515.HMPREF9103_01073 6.9e-78 296.6 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VAB7@1239,3F7M1@33958,4HKCS@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA gnl|extdb|FAM1079-i1-1.1_001646 797515.HMPREF9103_01072 1.6e-227 795.0 Lactobacillaceae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPA7@1239,3F51H@33958,4H9SD@91061,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP gnl|extdb|FAM1079-i1-1.1_001647 797515.HMPREF9103_01071 1.8e-125 455.3 Lactobacillaceae Bacteria 1TP76@1239,3F4RI@33958,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase gnl|extdb|FAM1079-i1-1.1_001648 797515.HMPREF9103_01070 6.1e-171 606.7 Lactobacillaceae fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPB7@1239,3F3W9@33958,4HBCU@91061,COG0331@1,COG0331@2 NA|NA|NA I Malonyl CoA-acyl carrier protein transacylase gnl|extdb|FAM1079-i1-1.1_001649 797515.HMPREF9103_01069 5.2e-34 149.8 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VGIY@1239,3F7ZJ@33958,4HP0V@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis gnl|extdb|FAM1079-i1-1.1_001650 797515.HMPREF9103_01068 1.3e-163 582.4 Lactobacillaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,3F3XP@33958,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids gnl|extdb|FAM1079-i1-1.1_001651 797515.HMPREF9103_01067 1.1e-78 299.3 Lactobacillaceae marR Bacteria 1VCUU@1239,3FC7K@33958,4HIUM@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001652 797515.HMPREF9103_01066 3.8e-78 297.4 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V3UN@1239,3FCD6@33958,4HHYD@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs gnl|extdb|FAM1079-i1-1.1_001653 797515.HMPREF9103_01063 2.7e-171 607.8 Lactobacillaceae gbuC ko:K02001,ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TP82@1239,3F4B3@33958,4H9MM@91061,COG2113@1,COG2113@2 NA|NA|NA E glycine betaine gnl|extdb|FAM1079-i1-1.1_001654 525318.HMPREF0497_2035 1.1e-131 476.1 Lactobacillaceae proW ko:K02001,ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1UHRI@1239,3F4W7@33958,4IS7D@91061,COG4176@1,COG4176@2 NA|NA|NA E glycine betaine gnl|extdb|FAM1079-i1-1.1_001655 797515.HMPREF9103_01060 8.6e-218 762.7 Lactobacillaceae gbuA 3.6.3.32 ko:K02000 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 Bacteria 1UHNE@1239,3FC38@33958,4HA9P@91061,COG4175@1,COG4175@2 NA|NA|NA E glycine betaine gnl|extdb|FAM1079-i1-1.1_001620 797515.HMPREF9103_01102 6.6e-185 653.3 Lactobacillaceae yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter gnl|extdb|FAM1079-i1-1.1_001622 797515.HMPREF9103_01099 2.1e-143 515.0 Lactobacillaceae recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1V72V@1239,3F4BY@33958,4HJ7R@91061,COG2137@1,COG2137@2 NA|NA|NA S Regulatory protein RecX gnl|extdb|FAM1079-i1-1.1_001625 797515.HMPREF9103_01096 2.6e-205 721.1 Lactobacillaceae mnaA 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1TQZT@1239,3F3KQ@33958,4HBI3@91061,COG0381@1,COG0381@2 NA|NA|NA G Belongs to the UDP-N-acetylglucosamine 2-epimerase family gnl|extdb|FAM1079-i1-1.1_001657 797515.HMPREF9103_00235 3.4e-118 431.0 Lactobacillaceae XK27_05795 ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_001658 797515.HMPREF9103_00234 5.3e-133 480.3 Lactobacillaceae 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001659 797515.HMPREF9103_00233 6.2e-165 586.6 Lactobacillaceae aguB 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 R01152 RC00096 ko00000,ko00001,ko01000 Bacteria 1TRMU@1239,3FB7W@33958,4HCTJ@91061,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase gnl|extdb|FAM1079-i1-1.1_001660 797515.HMPREF9103_00232 4.2e-245 853.6 Lactobacillaceae ko:K03292 ko00000 2.A.2 Bacteria 1TRA5@1239,3F3UZ@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_001661 797515.HMPREF9103_00231 1.8e-121 441.8 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V4M9@1239,3F4GW@33958,4HHJN@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase gnl|extdb|FAM1079-i1-1.1_001662 797515.HMPREF9103_00230 1.6e-61 241.9 Lactobacillaceae Bacteria 1U5WC@1239,2E6DR@1,3311A@2,3F6MC@33958,4IFK0@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001663 797515.HMPREF9103_00229 6.7e-53 213.0 Lactobacillaceae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1V6WV@1239,3F7WB@33958,4HIMA@91061,COG0509@1,COG0509@2 NA|NA|NA E glycine cleavage gnl|extdb|FAM1079-i1-1.1_001664 797515.HMPREF9103_00228 7.4e-197 693.0 Lactobacillaceae 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F4NC@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase gnl|extdb|FAM1079-i1-1.1_001665 797515.HMPREF9103_00227 6.6e-104 383.3 Lactobacillaceae Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG gnl|extdb|FAM1079-i1-1.1_001666 797515.HMPREF9103_00225 2.3e-24 117.5 Lactobacillaceae Bacteria 1U8JN@1239,2AJCA@1,319XM@2,3FB23@33958,4IIHM@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001667 797515.HMPREF9103_00223 5.5e-58 229.9 Lactobacillaceae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1U67B@1239,3F78R@33958,4IFXV@91061,COG0509@1,COG0509@2 NA|NA|NA E Glycine cleavage H-protein gnl|extdb|FAM1079-i1-1.1_001668 797515.HMPREF9103_00222 4.9e-159 567.0 Lactobacillaceae yeaE Bacteria 1TPM1@1239,3FB4U@33958,4HBIQ@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo keto gnl|extdb|FAM1079-i1-1.1_001669 797515.HMPREF9103_00221 1.3e-260 905.2 Lactobacillaceae ydbT ko:K08981 ko00000 Bacteria 1TSRJ@1239,3F3VB@33958,4HB8P@91061,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain gnl|extdb|FAM1079-i1-1.1_001670 797515.HMPREF9103_00220 6.6e-60 236.9 Lactobacillaceae ko:K09167 ko00000 Bacteria 1VFTS@1239,3F6GM@33958,4HGMB@91061,COG3402@1,COG3402@2 NA|NA|NA S Bacterial PH domain gnl|extdb|FAM1079-i1-1.1_001671 797515.HMPREF9103_00219 5.2e-215 753.4 Lactobacillaceae norA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08153,ko:K19576,ko:K19578 M00717,M00765 ko00000,ko00002,ko02000 2.A.1.2.10,2.A.1.2.70,2.A.1.2.8 Bacteria 1TS6K@1239,3F4X1@33958,4HB1V@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001672 797515.HMPREF9103_00218 5.2e-119 433.7 Lactobacillaceae kdgR Bacteria 1TSV2@1239,3FBGK@33958,4HFMP@91061,COG1802@1,COG1802@2 NA|NA|NA K FCD gnl|extdb|FAM1079-i1-1.1_001673 797515.HMPREF9103_00217 2.2e-266 925.2 Lactobacillaceae Bacteria 1UKTX@1239,3F5JY@33958,4ITK1@91061,COG4932@1,COG4932@2 NA|NA|NA M MucBP domain gnl|extdb|FAM1079-i1-1.1_001675 797515.HMPREF9103_00215 1.8e-47 194.9 Lactobacillaceae Bacteria 1VGC1@1239,3F89N@33958,4HQJ6@91061,COG4367@1,COG4367@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2316) gnl|extdb|FAM1079-i1-1.1_001676 797515.HMPREF9103_00214 8.5e-105 386.3 Lactobacillaceae desR ko:K02479,ko:K07693 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko02022 Bacteria 1TVTF@1239,3F4VH@33958,4HAJW@91061,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon gnl|extdb|FAM1079-i1-1.1_001677 797515.HMPREF9103_00213 9.4e-134 483.4 Lactobacillaceae desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TSUE@1239,3F3VR@33958,4HB9N@91061,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM1079-i1-1.1_001678 797515.HMPREF9103_00212 4.5e-127 460.7 Lactobacillaceae yvfS ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V7QG@1239,3F5Q7@33958,4HFU4@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter gnl|extdb|FAM1079-i1-1.1_001679 525318.HMPREF0497_0684 1.4e-103 382.9 Lactobacillaceae yvfR ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPJE@1239,3F58G@33958,4HB5U@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_001680 797515.HMPREF9103_00209 2.1e-35 154.5 Lactobacillaceae 2.3.1.12,2.3.1.61 ko:K00627,ko:K00658 ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00307 R00209,R02569,R02570,R02571,R08549 RC00004,RC02727,RC02742,RC02833,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1VK43@1239,3F7FF@33958,4IG1J@91061,COG0508@1,COG0508@2 NA|NA|NA C Biotin-requiring enzyme gnl|extdb|FAM1079-i1-1.1_001681 797515.HMPREF9103_00208 3e-167 594.3 Lactobacillaceae lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 1TQM4@1239,3F60J@33958,4H9SW@91061,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives gnl|extdb|FAM1079-i1-1.1_001682 797515.HMPREF9103_00207 1.4e-186 658.7 Lactobacillaceae lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F47T@33958,4HI5Q@91061,COG0095@1,COG0095@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family gnl|extdb|FAM1079-i1-1.1_001684 797515.HMPREF9103_00205 1.8e-107 395.2 Lactobacillaceae 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1VE0G@1239,3FB8R@33958,4HMHX@91061,COG2249@1,COG2249@2 NA|NA|NA S NADPH-dependent FMN reductase gnl|extdb|FAM1079-i1-1.1_001685 797515.HMPREF9103_00204 3.7e-79 300.8 Lactobacillaceae rmaD Bacteria 1V4SH@1239,3F6M5@33958,4HICC@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein gnl|extdb|FAM1079-i1-1.1_001686 1423743.JCM14108_3082 5.3e-135 487.3 Lactobacillaceae 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_001687 797515.HMPREF9103_00201 7.4e-161 573.2 Lactobacillaceae yjjC ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQHS@1239,3F4JT@33958,4HC34@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter gnl|extdb|FAM1079-i1-1.1_001688 797515.HMPREF9103_00200 9.3e-292 1008.8 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPIG@1239,3F4PV@33958,4H9SK@91061,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide antibiotics gnl|extdb|FAM1079-i1-1.1_001689 797515.HMPREF9103_00199 1.3e-95 355.9 Lactobacillaceae ko:K09017 ko00000,ko03000 Bacteria 1VG1F@1239,3F6KD@33958,4HPER@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001690 797515.HMPREF9103_00198 5.1e-153 547.0 Lactobacillaceae 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 1VSC9@1239,3F4RS@33958,4HUQI@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel gnl|extdb|FAM1079-i1-1.1_001691 797515.HMPREF9103_00197 9.9e-101 372.9 Lactobacillaceae rlpA ko:K03642 ko00000 Bacteria 1VI1P@1239,3F69W@33958,4HPZG@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif gnl|extdb|FAM1079-i1-1.1_001692 797515.HMPREF9103_00196 2.5e-115 421.4 Bacteria Bacteria COG4640@1,COG4640@2 NA|NA|NA KT response to antibiotic gnl|extdb|FAM1079-i1-1.1_001693 797515.HMPREF9103_00968 9.5e-118 429.5 Lactobacillaceae Bacteria 1U5V7@1239,29NYS@1,309WV@2,3F6J8@33958,4IFIU@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001694 797515.HMPREF9103_00969 1.2e-115 422.5 Lactobacillaceae 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3XW@1239,3F4YM@33958,4HDG1@91061,COG0664@1,COG0664@2 NA|NA|NA K Transcriptional regulator, Crp Fnr family gnl|extdb|FAM1079-i1-1.1_001696 525318.HMPREF0497_2516 2.2e-81 308.5 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V39N@1239,3F4QM@33958,4HF32@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component gnl|extdb|FAM1079-i1-1.1_001697 797515.HMPREF9103_00974 4.3e-132 477.2 Lactobacillaceae tenA 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 Bacteria 1U7DG@1239,3F9F9@33958,4IH9E@91061,COG0819@1,COG0819@2 NA|NA|NA K TENA THI-4 family protein gnl|extdb|FAM1079-i1-1.1_001698 797515.HMPREF9103_00976 2.7e-310 1070.5 Lactobacillaceae araB 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 Bacteria 1TP91@1239,3F4HI@33958,4HBGF@91061,COG1070@1,COG1070@2 NA|NA|NA G carbohydrate kinase FGGY gnl|extdb|FAM1079-i1-1.1_001699 797515.HMPREF9103_00977 7e-138 496.5 Lactobacillaceae araD 4.1.2.17,5.1.3.4 ko:K01628,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R02262,R05850 RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS00590 Bacteria 1TPDV@1239,3F43P@33958,4H9W0@91061,COG0235@1,COG0235@2 NA|NA|NA G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gnl|extdb|FAM1079-i1-1.1_001700 1185653.A1A1_14349 3.3e-12 77.8 Bacilli ko:K07726 ko00000,ko03000 Bacteria 1VEWZ@1239,4HP6G@91061,COG2944@1,COG2944@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001701 1033837.WANG_1100 1e-21 109.8 Lactobacillaceae higB-2 Bacteria 1U5P8@1239,3FAI9@33958,4II1M@91061,COG4737@1,COG4737@2 NA|NA|NA S RelE toxin of RelE / RelB toxin-antitoxin system gnl|extdb|FAM1079-i1-1.1_001702 797515.HMPREF9103_00979 3.7e-63 247.3 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1VE0E@1239,3F6KW@33958,4HMFJ@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain gnl|extdb|FAM1079-i1-1.1_001703 797515.HMPREF9103_00980 5.2e-46 189.9 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1W06G@1239,3F7FA@33958,4HZAG@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain gnl|extdb|FAM1079-i1-1.1_001704 797515.HMPREF9103_00981 0.0 1161.7 Lactobacillaceae ctpA 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase gnl|extdb|FAM1079-i1-1.1_001705 511437.Lbuc_1879 9.6e-50 203.0 Lactobacillaceae Bacteria 1V7AK@1239,3F78U@33958,4HJVT@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM1079-i1-1.1_001706 797515.HMPREF9103_00983 8.1e-188 662.9 Lactobacillaceae 1.1.1.219 ko:K00091 ko00000,ko01000 Bacteria 1UEMD@1239,3F5S3@33958,4HDN7@91061,COG0451@1,COG0451@2 NA|NA|NA GM Male sterility protein gnl|extdb|FAM1079-i1-1.1_001708 797515.HMPREF9103_00985 4.1e-133 480.7 Lactobacillaceae Bacteria 1V7U7@1239,3F491@33958,4HIUT@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM1079-i1-1.1_001709 797515.HMPREF9103_00986 2.3e-292 1010.7 Lactobacillaceae mco Bacteria 1TQSU@1239,3F520@33958,4HDD6@91061,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase gnl|extdb|FAM1079-i1-1.1_001710 797515.HMPREF9103_00987 8.4e-139 499.6 Lactobacillaceae epsG 2.4.1.293 ko:K00786,ko:K17250 ko00000,ko01000,ko01003 GT2 Bacteria 1V95V@1239,3FC1Y@33958,4HJ1J@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 gnl|extdb|FAM1079-i1-1.1_001711 797515.HMPREF9103_00988 2.2e-235 821.2 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1UFQ0@1239,3F4NV@33958,4IEW0@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family gnl|extdb|FAM1079-i1-1.1_001712 797515.HMPREF9103_00989 9e-175 619.4 Lactobacillaceae cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0008199,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009405,GO:0009987,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042301,GO:0042545,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0045229,GO:0046058,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051704,GO:0055086,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.1.2.2,3.1.4.17,3.1.4.53 ko:K01120,ko:K03651,ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,ko02025,map00230,map00670,map01100,map01110,map01130,map02025 M00048 R00191,R01234,R04325,R04326 RC00026,RC00197,RC00296,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1VJ4D@1239,3FC18@33958,4HNZU@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase gnl|extdb|FAM1079-i1-1.1_001713 797515.HMPREF9103_00991 4.8e-96 357.1 Lactobacillaceae ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3FB7G@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_001714 797515.HMPREF9103_00990 9.2e-127 459.5 Lactobacillaceae alkD Bacteria 1V4WB@1239,3F4B1@33958,4HFXG@91061,COG4912@1,COG4912@2 NA|NA|NA L DNA alkylation repair enzyme gnl|extdb|FAM1079-i1-1.1_001695 797515.HMPREF9103_00971 2.2e-122 444.9 Lactobacillaceae tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 Bacteria 1V9SR@1239,3F606@33958,4HK9S@91061,COG0819@1,COG0819@2 NA|NA|NA K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway gnl|extdb|FAM1079-i1-1.1_001716 797515.HMPREF9103_01779 1.2e-94 352.4 Lactobacillaceae Bacteria 1VHWM@1239,3F6Q3@33958,4IFMJ@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001717 797515.HMPREF9103_01778 5.2e-285 986.5 Lactobacillaceae norB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K08170 M00702 ko00000,ko00002,ko01504,ko02000 2.A.1.3.23,2.A.1.3.59 Bacteria 1TPV3@1239,3F5DE@33958,4HCJN@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator gnl|extdb|FAM1079-i1-1.1_001718 797515.HMPREF9103_01777 1e-110 406.0 Lactobacillaceae nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 1V1HG@1239,3F46H@33958,4HGJ9@91061,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine gnl|extdb|FAM1079-i1-1.1_001719 797515.HMPREF9103_01776 0.0 1494.6 Lactobacillaceae nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 1TR9K@1239,3F435@33958,4HBIY@91061,COG1328@1,COG1328@2 NA|NA|NA F Ribonucleoside-triphosphate reductase gnl|extdb|FAM1079-i1-1.1_001720 797515.HMPREF9103_01775 5.3e-128 463.8 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_001721 797515.HMPREF9103_01774 6.5e-149 533.5 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP4J@1239,3F3YW@33958,4HBGH@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001722 797515.HMPREF9103_01773 1.2e-128 465.7 Lactobacillaceae Bacteria 1UG8E@1239,3F657@33958,4HCV7@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family gnl|extdb|FAM1079-i1-1.1_001723 797515.HMPREF9103_01772 2e-46 191.4 Lactobacillaceae Bacteria 1U862@1239,29QIU@1,30BIB@2,3FAKB@33958,4II3K@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001724 797515.HMPREF9103_01771 2.1e-252 877.9 Lactobacillaceae araP ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.26 Bacteria 1UHPS@1239,3FBSI@33958,4IS5K@91061,COG0477@1,COG0477@2 NA|NA|NA U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family gnl|extdb|FAM1079-i1-1.1_001725 797515.HMPREF9103_01770 1.7e-133 481.9 Lactobacillaceae budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 1V4AH@1239,3F41S@33958,4HJ98@91061,COG3527@1,COG3527@2 NA|NA|NA H Belongs to the alpha-acetolactate decarboxylase family gnl|extdb|FAM1079-i1-1.1_001726 797515.HMPREF9103_01769 0.0 1088.6 Lactobacillaceae alsS 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM1079-i1-1.1_001727 797515.HMPREF9103_01768 1.4e-72 278.9 Lactobacillaceae Bacteria 1U65E@1239,3F73G@33958,4I05Z@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001728 1423743.JCM14108_1220 8.1e-88 330.1 Lactobacillaceae yjjG GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723,ko:K20862 ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120 M00125 R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280 RC00017,RC00697 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4614 Bacteria 1TWM7@1239,3FBF3@33958,4HEXU@91061,COG1011@1,COG1011@2 NA|NA|NA S HAD-hyrolase-like gnl|extdb|FAM1079-i1-1.1_001729 797515.HMPREF9103_01765 3.3e-88 330.9 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VC7X@1239,3FC5Z@33958,4HKH8@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family gnl|extdb|FAM1079-i1-1.1_001730 797515.HMPREF9103_01764 1.8e-167 595.1 Lactobacillaceae iolS ko:K06607 ko00000,ko01000 Bacteria 1TPIY@1239,3F40K@33958,4HA4Q@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_001731 797515.HMPREF9103_01763 4.2e-124 450.7 Lactobacillaceae relA2 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TSC9@1239,3FBJN@33958,4HBE0@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein gnl|extdb|FAM1079-i1-1.1_001732 797515.HMPREF9103_01762 2.8e-224 784.3 Lactobacillaceae Bacteria 1TPM6@1239,3F5ZG@33958,4HCEP@91061,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family gnl|extdb|FAM1079-i1-1.1_001733 797515.HMPREF9103_01761 2.9e-145 521.2 Lactobacillaceae Bacteria 1VBJA@1239,3F41J@33958,4HSVK@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase gnl|extdb|FAM1079-i1-1.1_001734 797515.HMPREF9103_01760 2.7e-236 824.3 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system gnl|extdb|FAM1079-i1-1.1_001735 797515.HMPREF9103_01759 6.8e-189 666.4 Lactobacillaceae hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKF@1239,3F4VU@33958,4HAYG@91061,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX gnl|extdb|FAM1079-i1-1.1_001736 797515.HMPREF9103_01758 9.3e-56 222.6 Lactobacillaceae Bacteria 1U6EV@1239,2C6D9@1,30AAX@2,3F7RI@33958,4IG6N@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001737 797515.HMPREF9103_01757 6.2e-162 576.6 Lactobacillaceae dkgB Bacteria 1TPM1@1239,3F4XF@33958,4HACK@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase gnl|extdb|FAM1079-i1-1.1_001738 797515.HMPREF9103_01756 3.6e-67 260.8 Lactobacillaceae Bacteria 1U5V4@1239,29NYR@1,309WU@2,3F6J0@33958,4IFIS@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001739 797515.HMPREF9103_01755 2e-153 548.5 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily gnl|extdb|FAM1079-i1-1.1_001741 797515.HMPREF9103_01752 1.8e-253 881.3 Lactobacillaceae gor 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase gnl|extdb|FAM1079-i1-1.1_001742 797515.HMPREF9103_01751 1.6e-131 475.3 Lactobacillaceae glpQ1 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4E3@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase gnl|extdb|FAM1079-i1-1.1_001743 797515.HMPREF9103_01750 2.4e-256 891.0 Lactobacillaceae ugpB ko:K05813 ko02010,map02010 M00198 ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 Bacteria 1TS64@1239,3FC76@33958,4HARC@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein gnl|extdb|FAM1079-i1-1.1_001744 797515.HMPREF9103_01749 4.1e-150 537.3 Lactobacillaceae ugpE ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TR0I@1239,3F4Q5@33958,4HB8C@91061,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease gnl|extdb|FAM1079-i1-1.1_001745 525318.HMPREF0497_0313 6.8e-157 560.1 Lactobacillaceae ugpA ko:K02025,ko:K05814,ko:K15771 ko02010,map02010 M00198,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3 Bacteria 1TSIQ@1239,3FCAR@33958,4HC0D@91061,COG1175@1,COG1175@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component gnl|extdb|FAM1079-i1-1.1_001746 797515.HMPREF9103_01747 1.9e-200 704.9 Lactobacillaceae ugpC 3.6.3.20 ko:K05816,ko:K10111,ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00599,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3,3.A.1.1.38 Bacteria 1TP2M@1239,3FC3B@33958,4HA50@91061,COG3842@1,COG3842@2 NA|NA|NA E Belongs to the ABC transporter superfamily gnl|extdb|FAM1079-i1-1.1_001748 797515.HMPREF9103_01744 4.5e-191 673.7 Lactobacillaceae Bacteria 1TRQB@1239,3F3M7@33958,4HAY3@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM1079-i1-1.1_001749 797515.HMPREF9103_01743 4.4e-135 487.3 Lactobacillaceae sfsA ko:K06206 ko00000 Bacteria 1V1GZ@1239,3F4KV@33958,4HCPN@91061,COG1489@1,COG1489@2 NA|NA|NA S Belongs to the SfsA family gnl|extdb|FAM1079-i1-1.1_001750 797515.HMPREF9103_01742 1.7e-69 268.9 Lactobacillaceae Bacteria 1VK2X@1239,3F7G9@33958,4HQFY@91061,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) gnl|extdb|FAM1079-i1-1.1_001751 797515.HMPREF9103_01741 3.1e-181 641.0 Lactobacillaceae iolS ko:K06607 ko00000,ko01000 Bacteria 1TPIY@1239,3F40K@33958,4HA4Q@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_001752 797515.HMPREF9103_01740 8.8e-148 529.6 Lactobacillaceae yxkD Bacteria 1TRAU@1239,3F44R@33958,4H9UY@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 gnl|extdb|FAM1079-i1-1.1_001753 797515.HMPREF9103_01739 2.1e-55 221.5 Lactobacillaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1VM30@1239,3F8A8@33958,4HRC4@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity gnl|extdb|FAM1079-i1-1.1_001754 1423743.JCM14108_2373 1.3e-45 189.1 Lactobacillaceae crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1U4G6@1239,3F6R4@33958,4IE88@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity gnl|extdb|FAM1079-i1-1.1_001755 797515.HMPREF9103_01718 1.4e-102 379.0 Lactobacillaceae Bacteria 1VQW3@1239,3F64W@33958,4HV4F@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane gnl|extdb|FAM1079-i1-1.1_001756 797515.HMPREF9103_01720 4.4e-239 833.6 Lactobacillaceae pucI ko:K03457 ko00000 2.A.39 Bacteria 1TS5W@1239,3F5M3@33958,4HBM7@91061,COG1953@1,COG1953@2 NA|NA|NA FH Permease for cytosine/purines, uracil, thiamine, allantoin gnl|extdb|FAM1079-i1-1.1_001757 797515.HMPREF9103_01721 4.3e-269 933.3 Lactobacillaceae allB 3.5.2.5 ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R02425 RC00680 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,3F3S3@33958,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily gnl|extdb|FAM1079-i1-1.1_001758 525318.HMPREF0497_0297 2e-84 318.5 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V2RP@1239,3FBNY@33958,4HGBA@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component gnl|extdb|FAM1079-i1-1.1_001759 797515.HMPREF9103_01723 3.7e-113 414.1 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1F8@1239,3F4WH@33958,4HFVS@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase gnl|extdb|FAM1079-i1-1.1_001760 1423780.LOT_1559 1.2e-80 305.8 Lactobacillaceae rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1V3JM@1239,3F3YX@33958,4HFP8@91061,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA gnl|extdb|FAM1079-i1-1.1_001762 797515.HMPREF9103_01726 4.2e-191 674.1 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease gnl|extdb|FAM1079-i1-1.1_001763 797515.HMPREF9103_01727 6.9e-158 563.1 Lactobacillaceae vicX 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ8E@1239,3F3S4@33958,4HAKD@91061,COG1235@1,COG1235@2 NA|NA|NA S domain protein gnl|extdb|FAM1079-i1-1.1_001765 797515.HMPREF9103_01730 3.9e-240 837.0 Lactobacillaceae yycH Bacteria 1V32Y@1239,3F4HR@33958,4HG2Q@91061,COG4863@1,COG4863@2 NA|NA|NA S YycH protein gnl|extdb|FAM1079-i1-1.1_001766 525318.HMPREF0497_0289 0.0 1139.4 Lactobacillaceae vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F45G@33958,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM1079-i1-1.1_001767 797515.HMPREF9103_01733 7.4e-132 476.5 Lactobacillaceae Bacteria 1TPQG@1239,3F4FB@33958,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator gnl|extdb|FAM1079-i1-1.1_001764 525318.HMPREF0497_0291 4.4e-125 454.1 Lactobacillaceae yycI Bacteria 1V1FW@1239,3F3PV@33958,4HFWZ@91061,COG4853@1,COG4853@2 NA|NA|NA S YycH protein gnl|extdb|FAM1079-i1-1.1_001768 1114972.AUAW01000022_gene1267 8.2e-83 313.5 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP4J@1239,3F3YW@33958,4HBGH@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001770 797515.HMPREF9103_01322 0.0 1298.9 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell gnl|extdb|FAM1079-i1-1.1_001771 1423780.LOT_1840 3.1e-18 99.4 Lactobacillaceae Bacteria 1U5DH@1239,2DKJ3@1,309NE@2,3F5MT@33958,4IF4V@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001772 1138822.PL11_00695 4.9e-83 315.1 Lactobacillaceae Bacteria 1UKTR@1239,29XME@1,30JCP@2,3F4CB@33958,4ITJW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001773 1423780.LOT_1840 1.6e-16 93.6 Lactobacillaceae Bacteria 1U5DH@1239,2DKJ3@1,309NE@2,3F5MT@33958,4IF4V@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001774 1138822.PL11_00695 9.2e-82 310.8 Lactobacillaceae Bacteria 1UKTR@1239,29XME@1,30JCP@2,3F4CB@33958,4ITJW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001775 797515.HMPREF9103_01650 1.2e-14 87.4 Lactobacillaceae Bacteria 1U5DH@1239,2DKJ3@1,309NE@2,3F5MT@33958,4IF4V@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001776 1071400.LBUCD034_0240 5.2e-17 94.7 Bacteria ko:K07273 ko00000 Bacteria COG3757@1,COG3757@2 NA|NA|NA M lysozyme activity gnl|extdb|FAM1079-i1-1.1_001778 1423754.BALY01000015_gene455 4e-29 134.0 Firmicutes relB ko:K07473 ko00000,ko02048 Bacteria 1VB9J@1239,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family gnl|extdb|FAM1079-i1-1.1_001779 797515.HMPREF9103_01316 1.6e-163 582.0 Lactobacillaceae qorB 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1TT90@1239,3F4UU@33958,4HC1K@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family gnl|extdb|FAM1079-i1-1.1_001780 797515.HMPREF9103_01315 1.1e-42 178.7 Lactobacillaceae Bacteria 1U793@1239,29PZK@1,30AY2@2,3F953@33958,4IH3Z@91061 NA|NA|NA S zinc-ribbon domain gnl|extdb|FAM1079-i1-1.1_001781 797515.HMPREF9103_01314 2.2e-41 174.9 Lactobacillaceae Bacteria 1U6HU@1239,29PF9@1,30ADE@2,3F7Y6@33958,4IGA5@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001782 797515.HMPREF9103_01313 1.1e-217 762.3 Lactobacillaceae Bacteria 1U598@1239,2CC2J@1,309K5@2,3F58S@33958,4IF0I@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001783 797515.HMPREF9103_01312 5.3e-181 640.2 Lactobacillaceae ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1TPP9@1239,3F3XA@33958,4H9YJ@91061,COG0252@1,COG0252@2 NA|NA|NA EJ Asparaginase gnl|extdb|FAM1079-i1-1.1_001784 797515.HMPREF9103_01311 8.4e-63 246.1 Lactobacillaceae Bacteria 1U6DW@1239,2A5X0@1,30UP0@2,3F7P8@33958,4IG5K@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001785 797515.HMPREF9103_01310 3.3e-200 704.1 Lactobacillaceae potA 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 iSB619.SA_RS05380 Bacteria 1TP2M@1239,3F40H@33958,4H9MS@91061,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_001786 797515.HMPREF9103_01309 1.8e-134 485.3 Lactobacillaceae potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1TQ7Z@1239,3F4CM@33958,4HAYS@91061,COG1176@1,COG1176@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_001787 525318.HMPREF0497_1741 4e-126 457.6 Lactobacillaceae potC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSBO_1134.SBO_1939 Bacteria 1V0VD@1239,3F3ZN@33958,4H9ZC@91061,COG1177@1,COG1177@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_001788 797515.HMPREF9103_01306 2.1e-207 728.0 Lactobacillaceae potD ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 1TPY1@1239,3F3W1@33958,4HAET@91061,COG0687@1,COG0687@2 NA|NA|NA P ABC transporter gnl|extdb|FAM1079-i1-1.1_001789 797515.HMPREF9103_01305 8.8e-56 222.6 Lactobacillaceae Bacteria 1U6RT@1239,29PM1@1,30AJ7@2,3F8DQ@33958,4IGJ9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001790 1423807.BACO01000057_gene1670 1.7e-12 79.0 Lactobacillaceae Bacteria 1VQDB@1239,2EHZR@1,33BR8@2,3F91V@33958,4HRJT@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001793 797515.HMPREF9103_01302 3.9e-265 920.2 Lactobacillaceae ydiC1 Bacteria 1TPRN@1239,3F4D4@33958,4HBXJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001794 797515.HMPREF9103_01300 8.7e-151 540.4 Lactobacillaceae Bacteria 1UKTR@1239,29XME@1,30JCP@2,3F4CB@33958,4ITJW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001795 797515.HMPREF9103_01299 0.0 2311.2 Lactobacillaceae Bacteria 1UN2Q@1239,2CDRA@1,2Z7QN@2,3F8IP@33958,4IU5M@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001796 797515.HMPREF9103_01390 0.0 1618.2 Lactobacillaceae pacL1 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase gnl|extdb|FAM1079-i1-1.1_001797 797515.HMPREF9103_01389 1.5e-205 721.8 Lactobacillaceae asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC6@1239,3F4S9@33958,4HA9H@91061,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate gnl|extdb|FAM1079-i1-1.1_001798 797515.HMPREF9103_01388 3.3e-222 777.3 Lactobacillaceae aspC 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM1079-i1-1.1_001799 797515.HMPREF9103_01387 8.5e-142 509.6 Lactobacillaceae dapB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490 Bacteria 1TR9D@1239,3F3MA@33958,4HA5X@91061,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate gnl|extdb|FAM1079-i1-1.1_001800 797515.HMPREF9103_01386 2e-166 591.7 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) gnl|extdb|FAM1079-i1-1.1_001801 797515.HMPREF9103_01385 9.5e-222 775.8 Lactobacillaceae hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3F419@33958,4H9SG@91061,COG1473@1,COG1473@2 NA|NA|NA E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate gnl|extdb|FAM1079-i1-1.1_001802 797515.HMPREF9103_01384 9.1e-74 283.5 Lactobacillaceae dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1TQUJ@1239,3F3U0@33958,4H9KY@91061,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate gnl|extdb|FAM1079-i1-1.1_001803 797515.HMPREF9103_01383 1.5e-252 878.2 Lactobacillaceae lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 1TPE9@1239,3F3VJ@33958,4H9XW@91061,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine gnl|extdb|FAM1079-i1-1.1_001804 797515.HMPREF9103_01382 1.1e-267 928.7 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family gnl|extdb|FAM1079-i1-1.1_001805 797515.HMPREF9103_01381 8.5e-179 632.9 Lactobacillaceae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMN@1239,3F4F7@33958,4HBH4@91061,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan gnl|extdb|FAM1079-i1-1.1_001806 1071400.LBUCD034_2080 2.4e-17 94.4 Lactobacillaceae Bacteria 1U6N7@1239,29PIS@1,30AGX@2,3F86K@33958,4IGF7@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001807 797515.HMPREF9103_01378 8.3e-105 386.3 Lactobacillaceae Bacteria 1U5VH@1239,2C4FG@1,309X4@2,3F6K0@33958,4IFJ7@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001808 797515.HMPREF9103_01377 0.0 1488.4 Lactobacillaceae dinG 3.1.12.1,3.6.4.12 ko:K07464,ko:K10844 ko03022,ko03420,map03022,map03420 M00290 ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400 Bacteria 1TPNB@1239,3F473@33958,4HD6T@91061,COG1199@1,COG1199@2 NA|NA|NA KL DEAD_2 gnl|extdb|FAM1079-i1-1.1_001809 797515.HMPREF9103_01376 9.3e-158 562.8 Lactobacillaceae Bacteria 1TQDQ@1239,3F585@33958,4HCBR@91061,COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase family gnl|extdb|FAM1079-i1-1.1_001810 797515.HMPREF9103_01374 1.1e-55 222.2 Lactobacillaceae Bacteria 1U6YC@1239,29PRG@1,30APP@2,3F8Q6@33958,4IGSI@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001813 797515.HMPREF9103_01370 7.2e-26 122.5 Lactobacillaceae ko:K07729 ko00000,ko03000 Bacteria 1VEM3@1239,3FCDW@33958,4HNUV@91061,COG1476@1,COG1476@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain gnl|extdb|FAM1079-i1-1.1_001814 1121115.AXVN01000110_gene2335 5.2e-52 211.5 Blautia ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBQ@1239,247M8@186801,3XZCK@572511,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities gnl|extdb|FAM1079-i1-1.1_001815 797515.HMPREF9103_01665 4.5e-108 397.5 Firmicutes Bacteria 1UZ32@1239,28MQE@1,2ZAZB@2 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_001769 1423780.LOT_1518 7.9e-37 160.6 Lactobacillaceae Bacteria 1VDCA@1239,3F7ZF@33958,4HN0T@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain gnl|extdb|FAM1079-i1-1.1_001791 797515.HMPREF9103_01303 1.1e-46 192.2 Lactobacillaceae relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F72D@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family gnl|extdb|FAM1079-i1-1.1_001816 797515.HMPREF9103_02903 0.0 1125.2 Lactobacillaceae yjbQ ko:K03455,ko:K03499 ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 Bacteria 1TS32@1239,3F4AZ@33958,4H9Q5@91061,COG0475@1,COG0475@2,COG0569@1,COG0569@2 NA|NA|NA P TrkA C-terminal domain protein gnl|extdb|FAM1079-i1-1.1_001817 797515.HMPREF9103_02904 3.8e-75 287.3 Lactobacillaceae ohr Bacteria 1VY9T@1239,3F7CX@33958,4HXI7@91061,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein gnl|extdb|FAM1079-i1-1.1_001818 797515.HMPREF9103_02905 1.7e-295 1021.1 Lactobacillaceae ppcA 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 Bacteria 1V0S3@1239,3F5P7@33958,4HUB7@91061,COG1892@1,COG1892@2 NA|NA|NA H Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle gnl|extdb|FAM1079-i1-1.1_001819 525318.HMPREF0497_2128 8.5e-46 189.9 Lactobacillaceae Bacteria 1U6SP@1239,29PMN@1,30AJU@2,3F8F4@33958,4IGK8@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001820 797515.HMPREF9103_02908 2.2e-284 984.2 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase gnl|extdb|FAM1079-i1-1.1_001821 797515.HMPREF9103_02909 1.3e-218 765.4 Lactobacillaceae yceI ko:K08369 ko00000,ko02000 2.A.1 Bacteria 1TQM0@1239,3F3SE@33958,4HATA@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001822 797515.HMPREF9103_02910 3.2e-150 537.7 Lactobacillaceae nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1988,iHN637.CLJU_RS12010,iLJ478.TM1645 Bacteria 1TPQC@1239,3F58H@33958,4HB46@91061,COG0157@1,COG0157@2 NA|NA|NA H Quinolinate phosphoribosyl transferase, C-terminal domain gnl|extdb|FAM1079-i1-1.1_001823 797515.HMPREF9103_02911 3.6e-213 747.3 Lactobacillaceae namA Bacteria 1TPM6@1239,3F3UQ@33958,4HAS5@91061,COG1902@1,COG1902@2 NA|NA|NA C Oxidoreductase gnl|extdb|FAM1079-i1-1.1_001824 797515.HMPREF9103_02912 1.3e-90 339.0 Lactobacillaceae 2.3.1.82 ko:K18816 br01600,ko00000,ko01000,ko01504 Bacteria 1TVKK@1239,3F6TS@33958,4I3EK@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_001825 797515.HMPREF9103_02913 6.3e-63 246.5 Lactobacillaceae Bacteria 1VI8G@1239,2EIVY@1,33CM8@2,3F6Z1@33958,4IFT9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001827 797515.HMPREF9103_02915 6.8e-113 413.3 Lactobacillaceae ppaX_1 3.1.3.18,3.6.1.1 ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V9Z4@1239,3F3MN@33958,4IQ5C@91061,COG0546@1,COG0546@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase gnl|extdb|FAM1079-i1-1.1_001828 797515.HMPREF9103_02916 5.4e-278 963.0 Lactobacillaceae aldA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004029,GO:0004777,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0008911,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019299,GO:0019301,GO:0019317,GO:0019318,GO:0019320,GO:0019752,GO:0022607,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042354,GO:0042355,GO:0042802,GO:0043436,GO:0043648,GO:0043649,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0048037,GO:0050569,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 iAF1260.b1415,iBWG_1329.BWG_1242,iECDH10B_1368.ECDH10B_1541,iECDH1ME8569_1439.ECDH1ME8569_1358,iEcDH1_1363.EcDH1_2230,iJO1366.b1415,iJR904.b1415,iY75_1357.Y75_RS07435 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM1079-i1-1.1_001829 797515.HMPREF9103_02917 2.4e-214 751.1 Lactobacillaceae adhC 1.1.1.90 ko:K00055,ko:K06898 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8E@1239,3F3QP@33958,4HAH9@91061,COG1062@1,COG1062@2 NA|NA|NA C Zn-dependent alcohol dehydrogenases, class III gnl|extdb|FAM1079-i1-1.1_001831 797515.HMPREF9103_02919 1.3e-107 395.6 Lactobacillaceae Bacteria 1UFVB@1239,3F52C@33958,4IEZ6@91061,COG4640@1,COG4640@2 NA|NA|NA S zinc-ribbon domain gnl|extdb|FAM1079-i1-1.1_001834 797515.HMPREF9103_02922 0.0 1745.3 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus gnl|extdb|FAM1079-i1-1.1_001835 797515.HMPREF9103_02924 2.9e-257 894.0 Lactobacillaceae aspA 4.2.1.2,4.3.1.1 ko:K01679,ko:K01744 ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R00490,R01082 RC00316,RC00443,RC02799 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP3U@1239,3FBTC@33958,4HFM9@91061,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus gnl|extdb|FAM1079-i1-1.1_001836 797515.HMPREF9103_02925 5.4e-102 377.1 Lactobacillaceae Bacteria 1U5V1@1239,29NYP@1,309WS@2,3F6IX@33958,4IFIP@91061 NA|NA|NA S Domain of Unknown Function with PDB structure (DUF3862) gnl|extdb|FAM1079-i1-1.1_001837 797515.HMPREF9103_02927 1.4e-96 359.0 Lactobacillaceae Bacteria 1W6HU@1239,3F6V3@33958,4HY6F@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_001838 797515.HMPREF9103_02928 1.1e-109 402.5 Lactobacillaceae 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1VB36@1239,3F66F@33958,4HW64@91061,COG2249@1,COG2249@2 NA|NA|NA S Flavodoxin-like fold gnl|extdb|FAM1079-i1-1.1_001839 797515.HMPREF9103_02929 3.7e-102 377.5 Lactobacillaceae Bacteria 1V8YK@1239,3F6GD@33958,4HJ63@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_001840 797515.HMPREF9103_02930 0.0 1285.8 Lactobacillaceae ydgH GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006790,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0030312,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046505,GO:0046506,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901576 ko:K06994,ko:K07003 ko00000 Bacteria 1TQ7C@1239,3FCCY@33958,4HBM6@91061,COG1511@1,COG1511@2,COG2409@1,COG2409@2 NA|NA|NA S MMPL family gnl|extdb|FAM1079-i1-1.1_001841 525318.HMPREF0497_2104 1.8e-56 225.3 Lactobacillaceae Bacteria 1U7J7@1239,29Q5M@1,30B4W@2,3F9SZ@33958,4IHG4@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001842 797515.HMPREF9103_02932 5.1e-32 143.7 Lactobacillaceae yvlA Bacteria 1VIUB@1239,2DZIG@1,32VBI@2,3F7EN@33958,4HRZP@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001843 797515.HMPREF9103_02484 4.2e-264 916.8 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain gnl|extdb|FAM1079-i1-1.1_001844 797515.HMPREF9103_02483 4.1e-77 293.9 Bacilli yjcF 3.5.4.33,4.4.1.8 ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941,R10223 RC00056,RC00069,RC00382,RC00477,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007,ko03016 Bacteria 1VIP5@1239,4HQHU@91061,COG2153@1,COG2153@2 NA|NA|NA S Acetyltransferase GNAT Family gnl|extdb|FAM1079-i1-1.1_001845 797515.HMPREF9103_02482 7.9e-244 849.4 Lactobacillaceae XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,3F4H2@33958,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein gnl|extdb|FAM1079-i1-1.1_001846 797515.HMPREF9103_02481 2.5e-40 171.0 Lactobacillaceae gcvR ko:K07166 ko00000 Bacteria 1VENW@1239,3F811@33958,4HNJ4@91061,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family gnl|extdb|FAM1079-i1-1.1_001847 797515.HMPREF9103_02480 1.9e-98 365.2 Lactobacillaceae maa 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3F5U8@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose O-acetyltransferase gnl|extdb|FAM1079-i1-1.1_001848 797515.HMPREF9103_02479 4.4e-152 543.9 Lactobacillaceae tesE ko:K02509 ko00350,ko01120,map00350,map01120 R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 Bacteria 1TQVG@1239,3F515@33958,4HBMC@91061,COG3971@1,COG3971@2 NA|NA|NA Q hydratase gnl|extdb|FAM1079-i1-1.1_001849 797515.HMPREF9103_02478 5.8e-252 876.3 Lactobacillaceae uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F3WN@33958,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Belongs to the DNA polymerase type-Y family gnl|extdb|FAM1079-i1-1.1_001850 797515.HMPREF9103_02477 2.3e-53 214.5 Lactobacillaceae Bacteria 1U63B@1239,2BXI3@1,30A27@2,3F6Y0@33958,4IFSR@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001851 797515.HMPREF9103_02476 5.9e-79 300.1 Lactobacillaceae elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 1VAJY@1239,3F5B8@33958,4HIH7@91061,COG2153@1,COG2153@2 NA|NA|NA S GNAT family gnl|extdb|FAM1079-i1-1.1_001852 797515.HMPREF9103_02475 1.7e-156 558.5 Lactobacillaceae Bacteria 1TX72@1239,29HXA@1,304UB@2,3F62Y@33958,4I63E@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001853 797515.HMPREF9103_02474 5.8e-219 766.5 Lactobacillaceae mtnE 2.6.1.83 ko:K08969,ko:K10206 ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230 M00034,M00527 R07396,R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQD6@1239,3F4TW@33958,4HAHQ@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM1079-i1-1.1_001854 797515.HMPREF9103_02473 0.0 1387.5 Lactobacillaceae glnP ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQUG@1239,3F4HA@33958,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter gnl|extdb|FAM1079-i1-1.1_001855 797515.HMPREF9103_02472 2.3e-128 464.9 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10038 ko02010,map02010 M00227,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.2 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001826 797515.HMPREF9103_02914 1.6e-54 218.4 Lactobacillaceae Bacteria 1U69N@1239,29P8K@1,30A6Q@2,3F7DJ@33958,4IG0T@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001830 797515.HMPREF9103_02918 2.4e-102 378.3 Lactobacillaceae cat ko:K18234 ko00000,ko01000,ko01504 Bacteria 1TPKX@1239,3F4PX@33958,4HF6J@91061,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) gnl|extdb|FAM1079-i1-1.1_001833 797515.HMPREF9103_02921 6.5e-87 326.6 Lactobacillaceae paiA 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1V1RG@1239,3F73H@33958,4HFN7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_001869 1071400.LBUCD034_0595 5.4e-29 133.3 Lactobacillaceae tnp2PF3 Bacteria 1VXWA@1239,3F7AF@33958,4HXG3@91061,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain gnl|extdb|FAM1079-i1-1.1_001870 1423814.HMPREF0549_1148 1.4e-30 139.4 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_001871 575594.ACOH01000006_gene300 2.3e-51 209.1 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_001872 1114972.AUAW01000022_gene1267 3.4e-86 325.1 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP4J@1239,3F3YW@33958,4HBGH@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001873 1423780.LOT_1518 1.2e-39 169.9 Lactobacillaceae Bacteria 1VDCA@1239,3F7ZF@33958,4HN0T@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain gnl|extdb|FAM1079-i1-1.1_001874 1423780.LOT_1516 1.4e-38 166.8 Bacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1277@1,COG1277@2 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001875 1423780.LOT_1517 1.1e-20 105.9 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP4J@1239,3F3YW@33958,4HBGH@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001876 1423780.LOT_1518 4.9e-20 104.0 Lactobacillaceae Bacteria 1VDCA@1239,3F7ZF@33958,4HN0T@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain gnl|extdb|FAM1079-i1-1.1_001877 797515.HMPREF9103_00164 5.6e-56 223.4 Lactobacillaceae Bacteria 1U6FB@1239,29PD5@1,30ABC@2,3F7SH@33958,4IG76@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001878 797515.HMPREF9103_00163 5.5e-99 367.1 Lactobacillaceae Bacteria 1VK84@1239,3FBTS@33958,4ISVZ@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_001879 525318.HMPREF0497_1910 0.0 1375.1 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase gnl|extdb|FAM1079-i1-1.1_001880 797515.HMPREF9103_00160 7e-121 439.9 Lactobacillaceae Bacteria 1TQWQ@1239,3FC5Q@33958,4HF2N@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family gnl|extdb|FAM1079-i1-1.1_001881 797515.HMPREF9103_00158 8.3e-179 632.9 Lactobacillaceae oppF ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,3F4GM@33958,4H9YB@91061,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily gnl|extdb|FAM1079-i1-1.1_001882 797515.HMPREF9103_00157 7.6e-205 719.5 Lactobacillaceae oppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,3F41T@33958,4HA4E@91061,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily gnl|extdb|FAM1079-i1-1.1_001883 797515.HMPREF9103_00156 2.6e-154 551.6 Lactobacillaceae oppC ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,3F3W3@33958,4H9PZ@91061,COG1173@1,COG1173@2 NA|NA|NA EP ABC-type dipeptide oligopeptide nickel transport systems, permease components gnl|extdb|FAM1079-i1-1.1_001884 797515.HMPREF9103_00155 1.6e-163 582.0 Lactobacillaceae oppB ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP1S@1239,3F42T@33958,4HA2S@91061,COG0601@1,COG0601@2 NA|NA|NA P ABC-type dipeptide oligopeptide nickel transport systems, permease components gnl|extdb|FAM1079-i1-1.1_001885 797515.HMPREF9103_00154 3.3e-305 1053.5 Lactobacillaceae oppA ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein gnl|extdb|FAM1079-i1-1.1_001886 797515.HMPREF9103_00152 2.8e-304 1050.4 Lactobacillaceae oppA ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein gnl|extdb|FAM1079-i1-1.1_001887 797515.HMPREF9103_00151 0.0 1080.9 Lactobacillaceae oppA ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F97A@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle gnl|extdb|FAM1079-i1-1.1_001888 797515.HMPREF9103_00150 1.7e-309 1067.8 Lactobacillaceae oppA ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein gnl|extdb|FAM1079-i1-1.1_001889 797515.HMPREF9103_00149 3.9e-232 810.4 Lactobacillaceae hflX ko:K03665 ko00000,ko03009 Bacteria 1TNZB@1239,3F4B2@33958,4HACA@91061,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis gnl|extdb|FAM1079-i1-1.1_001890 797515.HMPREF9103_00148 6.3e-252 876.3 Lactobacillaceae steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid gnl|extdb|FAM1079-i1-1.1_001891 797515.HMPREF9103_00146 1.9e-35 156.0 Lactobacillaceae fadR Bacteria 1U76V@1239,3F91W@33958,4IH1N@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_001893 797515.HMPREF9103_00144 1.4e-173 615.5 Lactobacillaceae ko:K02529 ko00000,ko03000 Bacteria 1TRFH@1239,3F5CG@33958,4HBNT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family gnl|extdb|FAM1079-i1-1.1_001894 797515.HMPREF9103_00143 1.2e-118 432.6 Lactobacillaceae yhiD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V409@1239,3FB84@33958,4HC2G@91061,COG1285@1,COG1285@2 NA|NA|NA S MgtC family gnl|extdb|FAM1079-i1-1.1_001895 797515.HMPREF9103_00142 1.3e-112 412.5 Lactobacillaceae glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K02029,ko:K10002,ko:K10040 ko02010,ko02020,map02010,map02020 M00228,M00230,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 Bacteria 1UJM4@1239,3F3WJ@33958,4HBAS@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_001896 797515.HMPREF9103_00141 3.9e-108 397.5 Lactobacillaceae gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 1TQ5K@1239,3F3XW@33958,4HFBH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_001897 797515.HMPREF9103_00140 3.4e-152 544.3 Lactobacillaceae glnH ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F4GG@33958,4HAHV@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein gnl|extdb|FAM1079-i1-1.1_001898 797515.HMPREF9103_00139 2e-132 478.4 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10041 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_001899 797515.HMPREF9103_00138 5.3e-153 547.0 Lactobacillaceae eutJ ko:K04024 ko00000 Bacteria 1TQVV@1239,3F5YP@33958,4HGZA@91061,COG4820@1,COG4820@2 NA|NA|NA E Hsp70 protein gnl|extdb|FAM1079-i1-1.1_001900 525318.HMPREF0497_1893 7.3e-123 446.8 Lactobacillaceae Bacteria 1V7ET@1239,2C6F0@1,32RH8@2,3F4UC@33958,4HJDI@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001901 797515.HMPREF9103_00136 3.5e-24 118.6 Lactobacillaceae 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 R01206,R02334 RC00467 ko00000,ko00001,ko01000 GH18 Bacteria 1VN2E@1239,2EQI3@1,33I43@2,3F860@33958,4HR4S@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001902 797515.HMPREF9103_00135 3.7e-81 307.4 Lactobacillaceae zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711 ko00000,ko03000 Bacteria 1V6RI@1239,3F6W3@33958,4HIGM@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family gnl|extdb|FAM1079-i1-1.1_001903 797515.HMPREF9103_00134 1.5e-100 372.1 Lactobacillaceae gmk2 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1VGNR@1239,3FBBC@33958,4HQMY@91061,COG0194@1,COG0194@2 NA|NA|NA F Guanylate kinase gnl|extdb|FAM1079-i1-1.1_001905 797515.HMPREF9103_00132 1.5e-198 698.7 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family gnl|extdb|FAM1079-i1-1.1_001906 797515.HMPREF9103_00131 5.9e-31 139.4 Lactobacillaceae cspC ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7FW@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein gnl|extdb|FAM1079-i1-1.1_001907 862514.HMPREF0623_1086 6e-165 587.4 Lactobacillaceae gph ko:K03292,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.2 Bacteria 1TRYR@1239,3F51T@33958,4HCTH@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_001908 511437.Lbuc_1849 7.2e-293 1012.7 Lactobacillaceae uidA GO:0003674,GO:0003824,GO:0004553,GO:0004566,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0019389,GO:0019391,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDC@1239,3F4FZ@33958,4HCXR@91061,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family gnl|extdb|FAM1079-i1-1.1_001909 1423780.LOT_1067 3.2e-79 302.4 Lactobacillaceae Bacteria 1V28B@1239,3F6WX@33958,4HDPB@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein gnl|extdb|FAM1079-i1-1.1_001910 797515.HMPREF9103_00130 0.0 1598.9 Lactobacillaceae pepX 3.4.14.11 ko:K01281 ko00000,ko01000,ko01002 Bacteria 1TT78@1239,3F44E@33958,4HBA0@91061,COG2936@1,COG2936@2 NA|NA|NA E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline gnl|extdb|FAM1079-i1-1.1_001911 797515.HMPREF9103_00129 1.6e-179 635.2 Lactobacillaceae pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1UYT5@1239,3FBVV@33958,4ITF5@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates gnl|extdb|FAM1079-i1-1.1_001904 797515.HMPREF9103_00133 2.8e-78 297.7 Lactobacillaceae apfA 2.7.7.72,3.6.1.61 ko:K00974,ko:K18445 ko00230,ko03013,map00230,map03013 R00184,R09382,R09383,R09384,R09386 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1VAMK@1239,3F6NU@33958,4HKCB@91061,COG1051@1,COG1051@2 NA|NA|NA F Nudix hydrolase gnl|extdb|FAM1079-i1-1.1_001913 797515.HMPREF9103_00751 7.2e-135 486.5 Lactobacillaceae Bacteria 1TP1H@1239,3FBGM@33958,4IQ94@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold gnl|extdb|FAM1079-i1-1.1_001914 797515.HMPREF9103_00750 4.9e-201 706.8 Lactobacillaceae Bacteria 1U5BG@1239,2C146@1,309KY@2,3F5FW@33958,4IF2U@91061 NA|NA|NA S GDSL-like Lipase/Acylhydrolase gnl|extdb|FAM1079-i1-1.1_001915 797515.HMPREF9103_00749 7.9e-177 626.3 Lactobacillaceae Bacteria 1UKXX@1239,3F5E1@33958,4ITMJ@91061,COG2369@1,COG2369@2 NA|NA|NA S NAD:arginine ADP-ribosyltransferase gnl|extdb|FAM1079-i1-1.1_001916 797515.HMPREF9103_00748 0.0 2015.0 Lactobacillaceae Bacteria 1TPVY@1239,3F4AK@33958,4HD9X@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO gnl|extdb|FAM1079-i1-1.1_001917 797515.HMPREF9103_00747 2.5e-186 657.9 Lactobacillaceae Bacteria 1VCPM@1239,3F5I8@33958,4HNBT@91061,COG3594@1,COG3594@2 NA|NA|NA G Acyltransferase family gnl|extdb|FAM1079-i1-1.1_001918 797515.HMPREF9103_00746 2.8e-108 397.9 Lactobacillaceae Bacteria 1V2M4@1239,3F7D4@33958,4HMH5@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_001920 797515.HMPREF9103_00744 2.3e-153 548.1 Lactobacillaceae Bacteria 1V7GB@1239,3F5VT@33958,4I28M@91061,COG4990@1,COG4990@2 NA|NA|NA G Peptidase_C39 like family gnl|extdb|FAM1079-i1-1.1_001921 387344.LVIS_0229 3.1e-38 165.2 Lactobacillaceae fadR Bacteria 1U51T@1239,3F40Q@33958,4IETF@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_001922 1136177.KCA1_2529 6.9e-82 310.8 Lactobacillaceae Bacteria 1V9EI@1239,3F4GJ@33958,4HJCA@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family gnl|extdb|FAM1079-i1-1.1_001923 797515.HMPREF9103_00743 3.6e-216 757.3 Lactobacillaceae 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 R01057,R02749 RC00408 ko00000,ko00001,ko01000 Bacteria 1TP70@1239,3F3Y4@33958,4H9RU@91061,COG1015@1,COG1015@2 NA|NA|NA G Phosphotransfer between the C1 and C5 carbon atoms of pentose gnl|extdb|FAM1079-i1-1.1_001924 797515.HMPREF9103_00742 6.8e-223 779.6 Lactobacillaceae cdaR ko:K02647 ko00000,ko03000 Bacteria 1UKTM@1239,3F4E9@33958,4HY2V@91061,COG3835@1,COG3835@2 NA|NA|NA KT Purine catabolism regulatory protein-like family gnl|extdb|FAM1079-i1-1.1_001925 797515.HMPREF9103_00741 2e-49 201.4 Lactobacillaceae Bacteria 1U6CV@1239,29PB6@1,30A9C@2,3F7MG@33958,4IG4K@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001926 797515.HMPREF9103_00740 4.2e-141 507.3 Lactobacillaceae Bacteria 1TPZ8@1239,3F4N6@33958,4HAMW@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) gnl|extdb|FAM1079-i1-1.1_001927 797515.HMPREF9103_00739 2.5e-210 738.0 Lactobacillaceae gntT GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015128,GO:0015144,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K03299,ko:K06155 ko00000,ko02000 2.A.8,2.A.8.1.4 Bacteria 1TQ14@1239,3F3V0@33958,4HB0Y@91061,COG2610@1,COG2610@2 NA|NA|NA EG Gluconate gnl|extdb|FAM1079-i1-1.1_001928 797515.HMPREF9103_00738 1.3e-179 635.6 Lactobacillaceae ko:K02525 ko00000,ko03000 Bacteria 1TQSY@1239,3FC5E@33958,4HAJI@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family gnl|extdb|FAM1079-i1-1.1_001929 797515.HMPREF9103_00737 1.9e-110 405.2 Lactobacillaceae cadD Bacteria 1V97B@1239,3FB3X@33958,4HMGG@91061,COG4300@1,COG4300@2 NA|NA|NA P cadmium resistance gnl|extdb|FAM1079-i1-1.1_001930 797515.HMPREF9103_00736 1.2e-258 898.7 Lactobacillaceae gabT GO:0003674,GO:0003824,GO:0003867,GO:0008483,GO:0016740,GO:0016769 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 iHN637.CLJU_RS10045 Bacteria 1VS6F@1239,3F569@33958,4H9M7@91061,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gnl|extdb|FAM1079-i1-1.1_001931 797515.HMPREF9103_00735 9.4e-195 686.4 Lactobacillaceae Bacteria 1V01X@1239,3F7SQ@33958,4HVQJ@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM1079-i1-1.1_001932 797515.HMPREF9103_00734 1.6e-154 552.0 Lactobacillaceae 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1TT90@1239,3F4UU@33958,4HC1K@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family gnl|extdb|FAM1079-i1-1.1_001933 797515.HMPREF9103_00733 3.1e-92 344.4 Lactobacillaceae ko:K08996 ko00000 Bacteria 1VX0K@1239,3F6A5@33958,4HX2R@91061,COG3477@1,COG3477@2 NA|NA|NA S Protein of unknown function (DUF1440) gnl|extdb|FAM1079-i1-1.1_001934 797515.HMPREF9103_00729 4.8e-45 186.8 Lactobacillaceae ptsH ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1U6N0@1239,3F869@33958,4IGEV@91061,COG1925@1,COG1925@2 NA|NA|NA G PTS HPr component phosphorylation site gnl|extdb|FAM1079-i1-1.1_001935 797515.HMPREF9103_00728 5.2e-254 883.2 Lactobacillaceae pntB 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1TP6K@1239,3F53X@33958,4HFBD@91061,COG1282@1,COG1282@2 NA|NA|NA C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane gnl|extdb|FAM1079-i1-1.1_001936 797515.HMPREF9103_00727 4.1e-50 203.8 Lactobacillaceae pntAB 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1VBRE@1239,3F73J@33958,4HXKA@91061,COG3288@1,COG3288@2 NA|NA|NA C 4TM region of pyridine nucleotide transhydrogenase, mitoch gnl|extdb|FAM1079-i1-1.1_001937 797515.HMPREF9103_00726 2.2e-208 731.5 Lactobacillaceae pntA GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 1UI27@1239,3FBW7@33958,4ISBM@91061,COG3288@1,COG3288@2 NA|NA|NA C Alanine dehydrogenase/PNT, N-terminal domain gnl|extdb|FAM1079-i1-1.1_001938 797515.HMPREF9103_00725 4e-139 500.7 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase gnl|extdb|FAM1079-i1-1.1_001940 797515.HMPREF9103_00723 3.7e-108 397.5 Lactobacillaceae Bacteria 1VFW9@1239,3F4JD@33958,4HR1J@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) gnl|extdb|FAM1079-i1-1.1_001941 1423734.JCM14202_672 3.8e-101 375.2 Lactobacillaceae 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 Bacteria 1TRM3@1239,3FA03@33958,4HD75@91061,COG0154@1,COG0154@2 NA|NA|NA J Amidase gnl|extdb|FAM1079-i1-1.1_001943 334390.LAF_1214 1.4e-228 798.5 Lactobacillaceae tnp ko:K07493 ko00000 Bacteria 1TP4C@1239,3FB4C@33958,4HB0P@91061,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain gnl|extdb|FAM1079-i1-1.1_001944 525318.HMPREF0497_1849 1.7e-178 632.1 Lactobacillaceae pucG GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPS0@1239,3FB94@33958,4HBDW@91061,COG0075@1,COG0075@2 NA|NA|NA E Aminotransferase class-V gnl|extdb|FAM1079-i1-1.1_001945 1423734.JCM14202_2247 4.4e-145 521.2 Lactobacillaceae 3.5.1.6,3.5.1.87,3.5.3.9 ko:K02083,ko:K06016 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 M00046 R00905,R02423,R04666 RC00064,RC00096 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TQ0P@1239,3F5V9@33958,4HAE4@91061,COG0624@1,COG0624@2 NA|NA|NA E Peptidase family M20/M25/M40 gnl|extdb|FAM1079-i1-1.1_001946 1423743.JCM14108_2063 3.4e-201 708.0 Lactobacillaceae pucR ko:K09684 ko00000,ko03000 Bacteria 1TRDF@1239,3F5A2@33958,4H9KC@91061,COG2508@1,COG2508@2 NA|NA|NA QT Purine catabolism regulatory protein-like family gnl|extdb|FAM1079-i1-1.1_001947 1423743.JCM14108_2377 1.3e-180 639.4 Lactobacillaceae allB 3.5.2.5 ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R02425 RC00680 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,3F3S3@33958,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily gnl|extdb|FAM1079-i1-1.1_001948 1423743.JCM14108_2067 4e-206 724.2 Lactobacillaceae pucI ko:K03457 ko00000 2.A.39 Bacteria 1TS5W@1239,3F5M3@33958,4HBM7@91061,COG1953@1,COG1953@2 NA|NA|NA FH Permease for cytosine/purines, uracil, thiamine, allantoin gnl|extdb|FAM1079-i1-1.1_001949 1423806.JCM15457_1828 1.8e-113 415.6 Lactobacillaceae blpF ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family gnl|extdb|FAM1079-i1-1.1_001950 1423806.JCM15457_1827 1.5e-57 229.6 Lactobacillaceae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_001952 1071400.LBUCD034_1601 6.9e-239 832.8 Lactobacillaceae Bacteria 1UYND@1239,3FBNE@33958,4IRAQ@91061,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_001953 1071400.LBUCD034_1602 3.3e-135 487.6 Lactobacillaceae Bacteria 1TPPI@1239,3FB7E@33958,4HD0T@91061,COG1484@1,COG1484@2 NA|NA|NA L Bacterial dnaA protein gnl|extdb|FAM1079-i1-1.1_001951 1423806.JCM15457_1826 1.1e-83 316.6 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_001954 797515.HMPREF9103_00244 1.2e-226 792.3 Lactobacillaceae Bacteria 1TPRN@1239,3F3XY@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001955 797515.HMPREF9103_00246 4.9e-111 407.1 Lactobacillaceae Bacteria 1UJSC@1239,3F4ZZ@33958,4HCVT@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family gnl|extdb|FAM1079-i1-1.1_001956 525318.HMPREF0497_0641 6.9e-78 297.0 Lactobacillaceae dhaS Bacteria 1V5RP@1239,3F6G5@33958,4I2U4@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001957 797515.HMPREF9103_00248 2.2e-156 558.1 Lactobacillaceae Bacteria 1TPM1@1239,3FB4S@33958,4HAG6@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase gnl|extdb|FAM1079-i1-1.1_001959 797515.HMPREF9103_00253 1.9e-229 801.6 Lactobacillaceae Bacteria 1UKTR@1239,29XME@1,30JCP@2,3F4CB@33958,4ITJW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001960 797515.HMPREF9103_00254 1.3e-65 255.8 Lactobacillaceae Bacteria 1U7D0@1239,29NZ5@1,31616@2,3F9E6@33958,4IH8I@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001961 797515.HMPREF9103_00255 3.2e-80 304.3 Lactobacillaceae Bacteria 1U5VU@1239,29NZ5@1,309XA@2,3F6KS@33958,4IFJM@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001963 797515.HMPREF9103_00258 4.6e-293 1013.1 Lactobacillaceae xylB 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3FCAE@33958,4HBRJ@91061,COG1070@1,COG1070@2 NA|NA|NA G Xylulose kinase gnl|extdb|FAM1079-i1-1.1_001964 1071400.LBUCD034_0429 6e-260 902.9 Lactobacillaceae xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 iECO26_1355.ECO26_5036,iHN637.CLJU_RS08960,iPC815.YPO4038 Bacteria 1TQW2@1239,3F5ME@33958,4H9WG@91061,COG2115@1,COG2115@2 NA|NA|NA G Belongs to the xylose isomerase family gnl|extdb|FAM1079-i1-1.1_001965 797515.HMPREF9103_00262 1.4e-202 712.2 Lactobacillaceae Bacteria 1TSUK@1239,3F3S1@33958,4H9X7@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001966 797515.HMPREF9103_03222 1.2e-79 302.4 Lactobacillaceae ko:K03719 ko00000,ko03000,ko03036 Bacteria 1V3MI@1239,3F6FN@33958,4HJUY@91061,COG1522@1,COG1522@2 NA|NA|NA K AsnC family gnl|extdb|FAM1079-i1-1.1_001967 797515.HMPREF9103_03221 4.3e-253 880.2 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM1079-i1-1.1_001968 797515.HMPREF9103_03220 5.6e-214 750.0 Lactobacillaceae xylR Bacteria 1TQCE@1239,3F540@33958,4HDE3@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family gnl|extdb|FAM1079-i1-1.1_001969 525318.HMPREF0497_0622 1.8e-243 848.2 Lactobacillaceae xylT Bacteria 1TREV@1239,3F3ZS@33958,4HAN1@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001970 1423807.BACO01000014_gene354 2.1e-48 199.1 Lactobacillaceae maa 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3FBEM@33958,4HGH2@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase gnl|extdb|FAM1079-i1-1.1_001971 797515.HMPREF9103_03219 3e-218 764.2 Lactobacillaceae Bacteria 1TPB5@1239,3F4TS@33958,4HAUM@91061,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001972 1071400.LBUCD034_0424 0.0 1391.7 Lactobacillaceae uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP0A@1239,3FC8S@33958,4HUZS@91061,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter gnl|extdb|FAM1079-i1-1.1_001973 797515.HMPREF9103_03216 7.9e-180 636.3 Lactobacillaceae Bacteria 1U7GE@1239,29XME@1,30B39@2,3F9M6@33958,4IHCK@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001974 1133569.AHYZ01000056_gene958 4.2e-19 100.5 Lactobacillaceae relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F72D@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family gnl|extdb|FAM1079-i1-1.1_001975 1140001.I571_02157 1.2e-20 105.9 Enterococcaceae Bacteria 1VQDB@1239,2EHZR@1,33BR8@2,4B3UD@81852,4HRJT@91061 NA|NA|NA S PemK-like, MazF-like toxin of type II toxin-antitoxin system gnl|extdb|FAM1079-i1-1.1_001976 797515.HMPREF9103_03215 1.3e-176 625.5 Lactobacillaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPFV@1239,3FC4P@33958,4HBFE@91061,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate gnl|extdb|FAM1079-i1-1.1_001977 797515.HMPREF9103_03214 9.4e-118 429.5 Lactobacillaceae pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1V1BZ@1239,3F487@33958,4HFV7@91061,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) gnl|extdb|FAM1079-i1-1.1_001978 797515.HMPREF9103_03213 2.8e-131 474.6 Lactobacillaceae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1TPPH@1239,3F47Y@33958,4HAJ2@91061,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) gnl|extdb|FAM1079-i1-1.1_001980 797515.HMPREF9103_03211 4.9e-216 756.9 Lactobacillaceae naiP Bacteria 1TQM0@1239,3F3SE@33958,4HATA@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001981 797515.HMPREF9103_03210 1.4e-150 538.9 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase gnl|extdb|FAM1079-i1-1.1_001982 797515.HMPREF9103_03209 2.2e-131 474.9 Lactobacillaceae Bacteria 1UZS4@1239,3F6WK@33958,4HI98@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain gnl|extdb|FAM1079-i1-1.1_001983 797515.HMPREF9103_03208 2.4e-112 411.4 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3F47V@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose O-acetyltransferase gnl|extdb|FAM1079-i1-1.1_001984 797515.HMPREF9103_03207 8.5e-116 422.9 Lactobacillaceae ppaX_1 3.1.3.18,3.6.1.1 ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V9Z4@1239,3F5TX@33958,4IQ5C@91061,COG0546@1,COG0546@2 NA|NA|NA S haloacid dehalogenase-like hydrolase gnl|extdb|FAM1079-i1-1.1_001985 1423780.LOT_0767 7.6e-163 579.7 Lactobacillaceae pepI 3.4.11.5,3.5.1.101 ko:K01259,ko:K18457 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRMT@1239,3F40N@33958,4HE23@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates gnl|extdb|FAM1079-i1-1.1_001986 1423780.LOT_2303 8.8e-30 137.5 Lactobacillaceae Bacteria 1U5D7@1239,29NU6@1,309N9@2,3F5M2@33958,4IF4I@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_001987 797515.HMPREF9103_03204 1.2e-140 505.8 Lactobacillaceae Bacteria 1TQTU@1239,3F6IF@33958,4HDUC@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase gnl|extdb|FAM1079-i1-1.1_001988 797515.HMPREF9103_03203 0.0 1355.5 Lactobacillaceae 3.2.1.185 ko:K09955,ko:K18205 ko00000,ko01000 GH127 Bacteria 1TNYA@1239,3F57Z@33958,4HDGR@91061,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 gnl|extdb|FAM1079-i1-1.1_001989 797515.HMPREF9103_03202 5.5e-245 853.2 Lactobacillaceae Bacteria 1V3NJ@1239,3F4KD@33958,4HTUC@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM1079-i1-1.1_001990 797515.HMPREF9103_03200 5.6e-180 636.7 Firmicutes Bacteria 1UN2X@1239,COG4977@1,COG4977@2 NA|NA|NA K AraC-like ligand binding domain gnl|extdb|FAM1079-i1-1.1_001991 1138822.PL11_07035 6e-41 174.9 Lactobacillaceae Bacteria 1UKTN@1239,3F5JQ@33958,4ITJU@91061,COG4977@1,COG4977@2 NA|NA|NA K AraC family transcriptional regulator gnl|extdb|FAM1079-i1-1.1_001992 1114972.AUAW01000010_gene948 1.1e-102 380.2 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGJ@1239,3F48R@33958,4HADZ@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose gnl|extdb|FAM1079-i1-1.1_001993 1423743.JCM14108_2989 4.1e-62 245.0 Lactobacillaceae gph ko:K03292,ko:K05820 ko00000,ko02000 2.A.1.27,2.A.2 Bacteria 1TRA5@1239,3FBC4@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_001958 525318.HMPREF0497_0638 0.0 1289.6 Lactobacillaceae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase gnl|extdb|FAM1079-i1-1.1_001962 525318.HMPREF0497_0632 2e-201 708.4 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_001994 797515.HMPREF9103_00868 2.3e-81 308.1 Lactobacillaceae greA ko:K03624,ko:K04760 ko00000,ko03021 Bacteria 1V1G3@1239,3F6ZK@33958,4HW8H@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides gnl|extdb|FAM1079-i1-1.1_001995 797515.HMPREF9103_00869 2.6e-109 401.4 Lactobacillaceae dedA 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1TS2R@1239,3F5F9@33958,4HA51@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein gnl|extdb|FAM1079-i1-1.1_001996 797515.HMPREF9103_00870 5.1e-181 640.2 Lactobacillaceae Bacteria 1TQ12@1239,3F4U1@33958,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_001997 797515.HMPREF9103_00871 8.6e-153 546.2 Lactobacillaceae endA ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease gnl|extdb|FAM1079-i1-1.1_001998 797515.HMPREF9103_00872 9.7e-88 329.3 Lactobacillaceae Bacteria 1VD8D@1239,3FBGH@33958,4IQ7Z@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain gnl|extdb|FAM1079-i1-1.1_001999 797515.HMPREF9103_00873 5.2e-136 490.3 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase gnl|extdb|FAM1079-i1-1.1_002000 797515.HMPREF9103_00874 7.5e-123 446.4 Lactobacillaceae tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 Bacteria 1V9SR@1239,3F606@33958,4HK9S@91061,COG0819@1,COG0819@2 NA|NA|NA K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway gnl|extdb|FAM1079-i1-1.1_002001 797515.HMPREF9103_00875 1.2e-38 165.2 Lactobacillaceae Bacteria 1TZSR@1239,2DJKT@1,306H4@2,3FAQU@33958,4II7J@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002002 797515.HMPREF9103_00877 8e-54 216.1 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein gnl|extdb|FAM1079-i1-1.1_002003 797515.HMPREF9103_00878 9.9e-274 948.7 Lactobacillaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K09014 ko00000 Bacteria 1TQ21@1239,3F44I@33958,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB gnl|extdb|FAM1079-i1-1.1_002004 797515.HMPREF9103_00879 4.2e-77 293.9 Lactobacillaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,3F6WP@33958,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family gnl|extdb|FAM1079-i1-1.1_002005 797515.HMPREF9103_00880 1.3e-243 848.6 Lactobacillaceae sufS 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TQ1W@1239,3F3UP@33958,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine gnl|extdb|FAM1079-i1-1.1_002006 797515.HMPREF9103_00881 7.6e-244 849.4 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,3F4BR@33958,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD gnl|extdb|FAM1079-i1-1.1_002007 797515.HMPREF9103_00882 1.5e-149 535.4 Lactobacillaceae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,3F3XT@33958,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC gnl|extdb|FAM1079-i1-1.1_002008 797515.HMPREF9103_00884 0.0 2931.4 Lactobacillaceae gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1,2.1.1.21 ko:K00265,ko:K00284,ko:K22083 ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R01586,R10086 RC00006,RC00010,RC00554,RC02799 ko00000,ko00001,ko01000 iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 Bacteria 1TQ0B@1239,3F4TU@33958,4HA4G@91061,COG0067@1,COG0067@2,COG0069@1,COG0069@2 NA|NA|NA E GXGXG motif gnl|extdb|FAM1079-i1-1.1_002009 797515.HMPREF9103_00885 1.9e-288 997.7 Lactobacillaceae gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 1TQ1A@1239,3FB6A@33958,4HAD5@91061,COG0493@1,COG0493@2 NA|NA|NA E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gnl|extdb|FAM1079-i1-1.1_002010 797515.HMPREF9103_00886 4.8e-264 916.8 Lactobacillaceae Bacteria 1UXZ2@1239,3F3NM@33958,4HDT0@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM1079-i1-1.1_002011 797515.HMPREF9103_00178 1e-259 902.1 Lactobacillaceae eutB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009350,GO:0032991,GO:0044424,GO:0044444,GO:0044464,GO:1902494 4.3.1.7 ko:K03735,ko:K16785 ko00564,ko01100,ko02010,map00564,map01100,map02010 M00582 R00749 RC00370 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iAPECO1_1312.APECO1_4107,iECOK1_1307.ECOK1_2756,iECS88_1305.ECS88_2629,iUMN146_1321.UM146_04425,iUTI89_1310.UTI89_C2774 Bacteria 1TP15@1239,3F4NK@33958,4HBSM@91061,COG4303@1,COG4303@2 NA|NA|NA E Ethanolamine ammonia lyase large subunit (EutB) gnl|extdb|FAM1079-i1-1.1_002012 797515.HMPREF9103_00179 1.1e-150 539.3 Lactobacillaceae eutC GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0009350,GO:0019842,GO:0031419,GO:0032991,GO:0036094,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363,GO:1902494 4.3.1.7 ko:K03736 ko00564,ko01100,map00564,map01100 R00749 RC00370 ko00000,ko00001,ko01000 iECNA114_1301.ECNA114_2515,iECSF_1327.ECSF_2301 Bacteria 1TSZM@1239,3F4ZX@33958,4HDFG@91061,COG4302@1,COG4302@2 NA|NA|NA E Ethanolamine ammonia-lyase light chain (EutC) gnl|extdb|FAM1079-i1-1.1_002013 797515.HMPREF9103_00180 6.6e-66 256.9 Lactobacillaceae gbsA 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM1079-i1-1.1_002015 797515.HMPREF9103_01220 9.9e-280 968.8 Lactobacillaceae ko:K02538 ko00000,ko03000 Bacteria 1VRI5@1239,3F5RF@33958,4HV34@91061,COG3711@1,COG3711@2 NA|NA|NA K transcriptional antiterminator gnl|extdb|FAM1079-i1-1.1_002017 797515.HMPREF9103_01217 7.4e-306 1056.2 Bacilli htaA 3.4.21.72 ko:K01347,ko:K12056 ko00000,ko01000,ko01002,ko02000,ko02044 1.B.12.3,3.A.7.11.1 Bacteria 1V15F@1239,4HFCE@91061,COG3266@1,COG3266@2,COG4886@1,COG4886@2 NA|NA|NA N the current gene model (or a revised gene model) may contain a gnl|extdb|FAM1079-i1-1.1_002018 797515.HMPREF9103_01217 0.0 1910.2 Bacilli htaA 3.4.21.72 ko:K01347,ko:K12056 ko00000,ko01000,ko01002,ko02000,ko02044 1.B.12.3,3.A.7.11.1 Bacteria 1V15F@1239,4HFCE@91061,COG3266@1,COG3266@2,COG4886@1,COG4886@2 NA|NA|NA N the current gene model (or a revised gene model) may contain a gnl|extdb|FAM1079-i1-1.1_002020 1423724.BAMM01000031_gene2088 1.8e-07 63.5 Lactobacillaceae Bacteria 1U62F@1239,2CI40@1,3021Q@2,3F6VD@33958,4IFRI@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002024 511437.Lbuc_0445 5.3e-13 79.7 Lactobacillaceae Bacteria 1U790@1239,29PZI@1,30AY0@2,3F94W@33958,4IH3U@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002025 1071400.LBUCD034_1988 1.9e-06 60.5 Lactobacillaceae Bacteria 1U7F8@1239,29Q3S@1,30B2G@2,3F9IP@33958,4IHB7@91061 NA|NA|NA S SH3-like domain gnl|extdb|FAM1079-i1-1.1_002030 797515.HMPREF9103_01898 3.8e-165 587.8 Lactobacillaceae Bacteria 1VES7@1239,3F71K@33958,4HIEC@91061,COG5386@1,COG5386@2 NA|NA|NA M Iron Transport-associated domain gnl|extdb|FAM1079-i1-1.1_002031 797515.HMPREF9103_01899 6.9e-81 307.4 Lactobacillaceae ko:K14193 ko05150,map05150 ko00000,ko00001 Bacteria 1VES7@1239,3F6SK@33958,4HIEC@91061,COG5386@1,COG5386@2 NA|NA|NA M Iron Transport-associated domain gnl|extdb|FAM1079-i1-1.1_002033 797515.HMPREF9103_01901 8.8e-165 586.3 Lactobacillaceae isdF ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TPX6@1239,3F4T9@33958,4H9QQ@91061,COG0609@1,COG0609@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gnl|extdb|FAM1079-i1-1.1_002034 797515.HMPREF9103_01902 3.3e-138 497.7 Lactobacillaceae fhuC 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 1TP2Q@1239,3F4NB@33958,4HCKS@91061,COG1120@1,COG1120@2 NA|NA|NA HP ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_002035 797515.HMPREF9103_01903 0.0 1097.8 Lactobacillaceae ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TR6X@1239,3F4N1@33958,4HA14@91061,COG1252@1,COG1252@2 NA|NA|NA C NADH dehydrogenase gnl|extdb|FAM1079-i1-1.1_002036 797515.HMPREF9103_01904 6e-282 976.1 Lactobacillaceae cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 1TRH4@1239,3F4MJ@33958,4HA19@91061,COG1271@1,COG1271@2 NA|NA|NA C ubiquinol oxidase gnl|extdb|FAM1079-i1-1.1_002037 797515.HMPREF9103_01905 6e-172 610.1 Lactobacillaceae cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120 Bacteria 1TRYV@1239,3F40S@33958,4H9KF@91061,COG1294@1,COG1294@2 NA|NA|NA C Cytochrome d ubiquinol oxidase subunit II gnl|extdb|FAM1079-i1-1.1_002039 525318.HMPREF0497_1395 1.4e-272 945.3 Lactobacillaceae cydD ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1UHN5@1239,3F4PG@33958,4HAAB@91061,COG4987@1,COG4987@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC gnl|extdb|FAM1079-i1-1.1_002040 797515.HMPREF9103_00265 2.7e-161 574.7 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family gnl|extdb|FAM1079-i1-1.1_002041 797515.HMPREF9103_00266 0.0 1501.1 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase gnl|extdb|FAM1079-i1-1.1_002042 1423743.JCM14108_1294 1.6e-180 638.6 Lactobacillaceae trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPY7@1239,3F3V6@33958,4HA1K@91061,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family gnl|extdb|FAM1079-i1-1.1_002043 797515.HMPREF9103_00268 3.4e-169 600.9 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase gnl|extdb|FAM1079-i1-1.1_002044 797515.HMPREF9103_00269 3.9e-229 800.4 Lactobacillaceae mvaA 1.1.1.34,1.1.1.88,2.3.1.9 ko:K00021,ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081,R02082 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPNY@1239,3F3YY@33958,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family gnl|extdb|FAM1079-i1-1.1_002045 1423743.JCM14108_1297 4.9e-163 580.5 Lactobacillaceae Bacteria 1VT7R@1239,296WI@1,2ZU5A@2,3F4R1@33958,4HVBN@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002046 797515.HMPREF9103_00272 5.1e-133 480.3 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3F4WS@33958,4HC4I@91061,COG0846@1,COG0846@2 NA|NA|NA K SIR2 family gnl|extdb|FAM1079-i1-1.1_002047 797515.HMPREF9103_00273 2.1e-162 578.2 Lactobacillaceae yunF Bacteria 1TPX4@1239,3F40Y@33958,4HA0X@91061,COG1801@1,COG1801@2 NA|NA|NA F Protein of unknown function DUF72 gnl|extdb|FAM1079-i1-1.1_002048 797515.HMPREF9103_00274 0.0 1358.2 Lactobacillaceae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPA1@1239,3F3XR@33958,4H9VC@91061,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation gnl|extdb|FAM1079-i1-1.1_002049 797515.HMPREF9103_00275 6.9e-144 516.5 Lactobacillaceae tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1TNY1@1239,3F3N2@33958,4HA74@91061,COG0084@1,COG0084@2 NA|NA|NA L hydrolase, TatD family gnl|extdb|FAM1079-i1-1.1_002050 797515.HMPREF9103_00276 4.2e-98 364.0 Lactobacillaceae rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985,ko:K07476 ko00000,ko01000 Bacteria 1V3K3@1239,3F64F@33958,4HH5Y@91061,COG1658@1,COG1658@2 NA|NA|NA J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step gnl|extdb|FAM1079-i1-1.1_002051 525318.HMPREF0497_1409 1.1e-132 479.6 Lactobacillaceae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 1TP9W@1239,3F3VC@33958,4HA4R@91061,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits gnl|extdb|FAM1079-i1-1.1_002052 525318.HMPREF0497_1410 3.3e-40 170.6 Lactobacillaceae veg Bacteria 1VEQM@1239,3F7D3@33958,4HKF8@91061,COG4466@1,COG4466@2 NA|NA|NA S Biofilm formation stimulator VEG gnl|extdb|FAM1079-i1-1.1_002053 797515.HMPREF9103_00280 4.3e-158 563.9 Lactobacillaceae ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 1TPXV@1239,3F43W@33958,4HAV8@91061,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol gnl|extdb|FAM1079-i1-1.1_002054 797515.HMPREF9103_00281 3.4e-126 457.6 Lactobacillaceae fhuC ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1TQ68@1239,3F49M@33958,4HAZI@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter gnl|extdb|FAM1079-i1-1.1_002055 797515.HMPREF9103_00282 3.4e-133 481.1 Lactobacillaceae znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1V0SX@1239,3F4BC@33958,4HE09@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family gnl|extdb|FAM1079-i1-1.1_002056 797515.HMPREF9103_00283 1.8e-153 548.5 Lactobacillaceae purR 2.4.2.7 ko:K00759,ko:K09685 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1TPN9@1239,3F3NH@33958,4HB8I@91061,COG0503@1,COG0503@2 NA|NA|NA F pur operon repressor gnl|extdb|FAM1079-i1-1.1_002057 797515.HMPREF9103_00284 3.5e-231 807.4 Lactobacillaceae glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP88@1239,3F4I3@33958,4H9V5@91061,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain gnl|extdb|FAM1079-i1-1.1_002058 797515.HMPREF9103_00285 2.5e-178 631.3 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3U2@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) gnl|extdb|FAM1079-i1-1.1_002059 797515.HMPREF9103_00286 1.8e-57 228.4 Lactobacillaceae Bacteria 1U6IM@1239,29PFT@1,30ADY@2,3F7ZR@33958,4IGB0@91061 NA|NA|NA S Domain of unknown function (DUF3899) gnl|extdb|FAM1079-i1-1.1_002060 797515.HMPREF9103_00287 1.1e-147 529.3 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase gnl|extdb|FAM1079-i1-1.1_002061 797515.HMPREF9103_00288 4.9e-262 909.8 Lactobacillaceae ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 1TPVB@1239,3F442@33958,4HAX8@91061,COG1078@1,COG1078@2 NA|NA|NA S HD domain protein gnl|extdb|FAM1079-i1-1.1_002062 797515.HMPREF9103_00289 6.1e-154 550.1 Lactobacillaceae lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 ko00000,ko01000 Bacteria 1TQKA@1239,3F575@33958,4HCPS@91061,COG0095@1,COG0095@2 NA|NA|NA H biotin lipoate A B protein ligase gnl|extdb|FAM1079-i1-1.1_002063 797515.HMPREF9103_00290 8.5e-75 286.2 Lactobacillaceae ywiB Bacteria 1V8IZ@1239,3F6AI@33958,4HIW0@91061,COG4506@1,COG4506@2 NA|NA|NA S Domain of unknown function (DUF1934) gnl|extdb|FAM1079-i1-1.1_002064 797515.HMPREF9103_00291 2e-48 199.1 Lactobacillaceae rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Bacteria 1V6WX@1239,3F55D@33958,4HIUK@91061,COG3343@1,COG3343@2 NA|NA|NA K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling gnl|extdb|FAM1079-i1-1.1_002065 797515.HMPREF9103_00292 0.0 1090.5 Lactobacillaceae pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS01075,iNJ661.Rv1699 Bacteria 1TP34@1239,3F42X@33958,4H9X6@91061,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates gnl|extdb|FAM1079-i1-1.1_002067 797515.HMPREF9103_01850 6.6e-43 179.5 Lactobacillaceae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGU@1239,3F7D7@33958,4HKF0@91061,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 gnl|extdb|FAM1079-i1-1.1_002038 525318.HMPREF0497_1394 1.8e-285 988.0 Lactobacillaceae cydD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1TQ1P@1239,3F451@33958,4HAN0@91061,COG4988@1,COG4988@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD gnl|extdb|FAM1079-i1-1.1_002066 797515.HMPREF9103_01849 2.3e-248 864.4 Lactobacillaceae murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 iYO844.BSU37100 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine gnl|extdb|FAM1079-i1-1.1_002068 797515.HMPREF9103_01121 7.3e-32 142.5 Lactobacillaceae Bacteria 1W2HF@1239,28U5Y@1,2ZGBR@2,3F8NF@33958,4HRY4@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002069 797515.HMPREF9103_01122 5.9e-79 300.1 Lactobacillaceae merR ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1VZI5@1239,3FBBA@33958,4HYTH@91061,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002070 797515.HMPREF9103_01123 3.1e-24 117.1 Lactobacillaceae Bacteria 1U6Y8@1239,29PRB@1,30APJ@2,3F8Q1@33958,4IGSE@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002071 797515.HMPREF9103_01124 1.2e-157 562.4 Lactobacillaceae glxR 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 iJN678.mmsB Bacteria 1TR4F@1239,3F3XC@33958,4H9MA@91061,COG2084@1,COG2084@2 NA|NA|NA I Dehydrogenase gnl|extdb|FAM1079-i1-1.1_002072 797515.HMPREF9103_01125 2e-188 664.8 Lactobacillaceae rfbB 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,3F3R6@33958,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily gnl|extdb|FAM1079-i1-1.1_002073 797515.HMPREF9103_01127 1.4e-89 335.5 Lactobacillaceae Bacteria 1U7JE@1239,29Q64@1,30B52@2,3F9TH@33958,4IHGF@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002074 797515.HMPREF9103_01128 1.4e-220 771.9 Lactobacillaceae dhaT 1.1.1.1,1.1.1.202 ko:K00086,ko:K13954 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02377,R03119,R04880,R05233,R05234,R06917,R06927 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649 ko00000,ko00001,ko01000 iYL1228.KPN_03491 Bacteria 1TPB4@1239,3F4SZ@33958,4HAPA@91061,COG1454@1,COG1454@2 NA|NA|NA C Dehydrogenase gnl|extdb|FAM1079-i1-1.1_002075 797515.HMPREF9103_01129 5.1e-212 743.4 Lactobacillaceae metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F4CK@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme gnl|extdb|FAM1079-i1-1.1_002076 797515.HMPREF9103_01130 1.4e-133 482.3 Lactobacillaceae Bacteria 1VCPB@1239,3F69G@33958,4HN1D@91061,COG5523@1,COG5523@2 NA|NA|NA S Protein of unknown function (DUF975) gnl|extdb|FAM1079-i1-1.1_002077 797515.HMPREF9103_01131 1e-207 729.2 Lactobacillaceae Bacteria 1TQXU@1239,3FCA8@33958,4HAYB@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002079 797515.HMPREF9103_01133 1e-72 279.3 Lactobacillaceae Bacteria 1U6VM@1239,2ATQV@1,32622@2,3F8JZ@33958,4IGPI@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002080 797515.HMPREF9103_01135 8.1e-230 802.7 Lactobacillaceae hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAW@1239,3F40P@33958,4H9XK@91061,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine gnl|extdb|FAM1079-i1-1.1_002081 797515.HMPREF9103_01136 2.9e-111 407.9 Lactobacillaceae hly ko:K11068 ko00000,ko02042 Bacteria 1TSFK@1239,3F578@33958,4HAT2@91061,COG1272@1,COG1272@2 NA|NA|NA S protein, hemolysin III gnl|extdb|FAM1079-i1-1.1_002082 797515.HMPREF9103_01137 2.8e-79 301.2 Lactobacillaceae M1-874 ko:K13638,ko:K13640 ko00000,ko03000 Bacteria 1V7Z4@1239,3F7RF@33958,4HJXK@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) gnl|extdb|FAM1079-i1-1.1_002083 797515.HMPREF9103_01138 3e-63 247.7 Lactobacillaceae Bacteria 1U6RX@1239,29PM4@1,30AJA@2,3F8DX@33958,4IGJE@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002084 797515.HMPREF9103_01139 3.7e-123 447.6 Lactobacillaceae Bacteria 1VCPB@1239,3F69G@33958,4HN1D@91061,COG5523@1,COG5523@2 NA|NA|NA S Protein of unknown function (DUF975) gnl|extdb|FAM1079-i1-1.1_002086 797515.HMPREF9103_01141 3.4e-172 610.9 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V2YH@1239,3F4G3@33958,4HKBF@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 gnl|extdb|FAM1079-i1-1.1_002087 797515.HMPREF9103_01142 2.8e-117 427.9 Lactobacillaceae Bacteria 1U5QM@1239,2A1CJ@1,30PJI@2,3F6BE@33958,4IFEQ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002088 797515.HMPREF9103_01144 1.6e-88 332.8 Lactobacillaceae Bacteria 1V3YR@1239,2BVD0@1,32QT1@2,3F67T@33958,4HK85@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002089 797515.HMPREF9103_01145 7e-150 536.6 Lactobacillaceae ko:K09861 ko00000 Bacteria 1TR33@1239,3F4KR@33958,4HFN2@91061,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family gnl|extdb|FAM1079-i1-1.1_002090 797515.HMPREF9103_01146 2e-227 794.7 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1VUFQ@1239,3F4GB@33958,4HVI1@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family gnl|extdb|FAM1079-i1-1.1_002091 797515.HMPREF9103_01147 3.9e-170 604.0 Lactobacillaceae 3.2.1.37 ko:K01198,ko:K21701 ko00520,ko01100,map00520,map01100 R01433 RC00467 ko00000,ko00001,ko01000,ko03000 GH43 Bacteria 1UIVE@1239,3F68N@33958,4ITAQ@91061,COG4977@1,COG4977@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein gnl|extdb|FAM1079-i1-1.1_002092 797515.HMPREF9103_01148 6.1e-144 516.9 Lactobacillaceae yisR Bacteria 1UYDC@1239,3F5NH@33958,4HAAA@91061,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002094 797515.HMPREF9103_02188 5.2e-181 640.2 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1VSE2@1239,3F5BT@33958,4HUTX@91061,COG0604@1,COG0604@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM1079-i1-1.1_002095 797515.HMPREF9103_02190 5.3e-39 166.4 Lactobacillaceae Bacteria 1U77D@1239,2ATUG@1,31JDJ@2,3F92H@33958,4IH27@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002096 797515.HMPREF9103_02191 8.7e-173 612.8 Lactobacillaceae MA20_03535 1.1.1.399,1.1.1.95 ko:K00058,ko:K04496 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko04310,ko04330,ko05200,ko05220,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map04310,map04330,map05200,map05220 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_002097 797515.HMPREF9103_02192 2.1e-79 301.6 Lactobacillaceae Bacteria 1V3T8@1239,3FC6R@33958,4HH2F@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain gnl|extdb|FAM1079-i1-1.1_002098 797515.HMPREF9103_02194 5.4e-59 233.4 Lactobacillaceae Bacteria 1U65U@1239,29PCD@1,30A41@2,3F74X@33958,4IFVQ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002099 797515.HMPREF9103_02195 1.6e-261 908.3 Lactobacillaceae bmr3 Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002100 797515.HMPREF9103_02196 1.1e-84 319.3 Lactobacillaceae ko:K03830 ko00000,ko01000 Bacteria 1V6S5@1239,3F6HM@33958,4HJJY@91061,COG0454@1,COG0456@2 NA|NA|NA K GNAT family gnl|extdb|FAM1079-i1-1.1_002102 797515.HMPREF9103_02198 7.4e-163 579.7 Lactobacillaceae Bacteria 1V2AW@1239,3F3N7@33958,4HU2V@91061,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family gnl|extdb|FAM1079-i1-1.1_002103 797515.HMPREF9103_02199 5e-97 360.9 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VZE5@1239,3F73V@33958,4HYX4@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX amino terminal protease gnl|extdb|FAM1079-i1-1.1_002104 797515.HMPREF9103_02201 5.4e-152 543.5 Lactobacillaceae Bacteria 1VEC5@1239,3F50A@33958,4HKY6@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold gnl|extdb|FAM1079-i1-1.1_002105 797515.HMPREF9103_02202 9.1e-186 656.0 Lactobacillaceae lacM 3.2.1.23,3.2.1.35,3.2.1.51,3.2.1.97 ko:K01190,ko:K01197,ko:K01206,ko:K17624 ko00052,ko00511,ko00531,ko00600,ko01100,map00052,map00511,map00531,map00600,map01100 M00076,M00077 R01105,R01678,R03355,R04783,R06114,R07824,R07825,R10905 RC00049,RC00452 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko04147 GH101,GH29 Bacteria 1TRVA@1239,3F51Z@33958,4HFMH@91061,COG3250@1,COG3250@2 NA|NA|NA G beta-galactosidase gnl|extdb|FAM1079-i1-1.1_002106 525318.HMPREF0497_1161 0.0 1132.5 Lactobacillaceae lacZ 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1TPDC@1239,3F4EI@33958,4HANW@91061,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family gnl|extdb|FAM1079-i1-1.1_002107 797515.HMPREF9103_02205 4.3e-99 367.5 Lactobacillaceae eda 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1TS0F@1239,3FCB2@33958,4HFZ3@91061,COG0800@1,COG0800@2 NA|NA|NA G KDPG and KHG aldolase gnl|extdb|FAM1079-i1-1.1_002108 797515.HMPREF9103_02206 2.7e-88 331.3 Lactobacillaceae M1-874 ko:K13638,ko:K13640 ko00000,ko03000 Bacteria 1V7Z4@1239,3F6HK@33958,4HJXK@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) gnl|extdb|FAM1079-i1-1.1_002109 797515.HMPREF9103_02207 1.8e-156 558.5 Lactobacillaceae Bacteria 1TYCV@1239,3F572@33958,4HD8F@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 gnl|extdb|FAM1079-i1-1.1_002110 511437.Lbuc_0621 3.7e-47 194.1 Lactobacillaceae Bacteria 1U7PJ@1239,29PCD@1,30B7Q@2,3F9ZF@33958,4IHKW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002111 797515.HMPREF9103_02208 0.0 1092.8 Lactobacillaceae 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 R01498 RC00059,RC00451 ko00000,ko00001,ko01000 GH30 Bacteria 1URVQ@1239,3F5VR@33958,4HE4Z@91061,COG5520@1,COG5520@2 NA|NA|NA G Glycosyl hydrolase family 30 TIM-barrel domain gnl|extdb|FAM1079-i1-1.1_002078 797515.HMPREF9103_01132 1.3e-55 222.6 Lactobacillaceae Bacteria 1U7IH@1239,29Q5D@1,30B4B@2,3F9RM@33958,4IHF6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002101 797515.HMPREF9103_02197 5e-148 530.4 Lactobacillaceae Bacteria 1U75K@1239,29HXA@1,30AVH@2,3F909@33958,4IH08@91061 NA|NA|NA S Matrixin gnl|extdb|FAM1079-i1-1.1_002112 797515.HMPREF9103_00663 0.0 1162.1 Lactobacillaceae recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ gnl|extdb|FAM1079-i1-1.1_002115 1423743.JCM14108_1781 8.4e-88 330.1 Lactobacillaceae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_002116 797515.HMPREF9103_00658 2.1e-191 674.9 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_002117 797515.HMPREF9103_00657 2.7e-149 534.6 Lactobacillaceae metQ1 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family gnl|extdb|FAM1079-i1-1.1_002118 797515.HMPREF9103_00654 5.8e-205 719.9 Lactobacillaceae mdh 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 R02935,R02936 RC00169 ko00000,ko00001,ko01000 Bacteria 1TR0Z@1239,3F4JZ@33958,4HB6X@91061,COG2055@1,COG2055@2 NA|NA|NA C Belongs to the LDH2 MDH2 oxidoreductase family gnl|extdb|FAM1079-i1-1.1_002119 797515.HMPREF9103_00653 2.3e-97 361.7 Lactobacillaceae lacA 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1V06U@1239,3F63W@33958,4HW9U@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase gnl|extdb|FAM1079-i1-1.1_002120 797515.HMPREF9103_00652 8.7e-252 876.3 Lactobacillaceae Bacteria 1UYFY@1239,3F5T0@33958,4IF6F@91061,COG4934@1,COG4934@2 NA|NA|NA O Peptidase S53 propeptide gnl|extdb|FAM1079-i1-1.1_002121 797515.HMPREF9103_01280 2.3e-176 624.8 Lactobacillaceae pva2 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3FB8X@33958,4HMSI@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolases, choloylglycine hydrolase family gnl|extdb|FAM1079-i1-1.1_002123 525318.HMPREF0497_0182 2e-117 428.7 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VB8T@1239,3F57R@33958,4HFUB@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family gnl|extdb|FAM1079-i1-1.1_002125 797515.HMPREF9103_01284 6.6e-57 226.5 Lactobacillaceae Bacteria 1W6CU@1239,2DCK1@1,2ZEG6@2,3F7T1@33958,4I244@91061 NA|NA|NA S Protein of unknown function (DUF1648) gnl|extdb|FAM1079-i1-1.1_002126 525318.HMPREF0497_0927 8.3e-77 293.5 Firmicutes Bacteria 1W01Y@1239,COG0708@1,COG0708@2 NA|NA|NA L Exodeoxyribonuclease III gnl|extdb|FAM1079-i1-1.1_002127 797515.HMPREF9103_01285 6.8e-108 396.7 Lactobacillaceae ycfA Bacteria 1V3R8@1239,3F6RQ@33958,4HBEK@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002128 797515.HMPREF9103_02267 3.6e-185 654.4 Lactobacillaceae Bacteria 1TT59@1239,3F5HC@33958,4HC29@91061,COG1511@1,COG1511@2 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_002130 1071400.LBUCD034_2020 0.0 1229.9 Lactobacillaceae bglB 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 1TP0T@1239,3F43A@33958,4HAAG@91061,COG1472@1,COG1472@2 NA|NA|NA G hydrolase, family 3 gnl|extdb|FAM1079-i1-1.1_002131 797515.HMPREF9103_01832 8.5e-202 709.5 Lactobacillaceae uhpT Bacteria 1TQZ7@1239,3F54C@33958,4HERG@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002132 797515.HMPREF9103_01833 5.4e-95 353.6 Lactobacillaceae wecD Bacteria 1V6Z8@1239,3F6WQ@33958,4HMP7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family gnl|extdb|FAM1079-i1-1.1_002133 797515.HMPREF9103_01998 1.1e-28 132.1 Lactobacillaceae Bacteria 1U8GM@1239,29QQK@1,30BQD@2,3FAYQ@33958,4IIEG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002135 797515.HMPREF9103_01997 1.5e-144 518.8 Lactobacillaceae Bacteria 1U5D7@1239,29NU6@1,309N9@2,3F5M2@33958,4IF4I@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002136 1423780.LOT_1531 5.2e-113 414.1 Lactobacillaceae Bacteria 1U5A4@1239,2DKIJ@1,309KI@2,3F5BZ@33958,4IF1K@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002138 797515.HMPREF9103_01996 3.3e-169 600.9 Lactobacillaceae Bacteria 1V7K6@1239,3F5SM@33958,4HJ7J@91061,COG4926@1,COG4926@2 NA|NA|NA S Phage minor structural protein gnl|extdb|FAM1079-i1-1.1_002139 797515.HMPREF9103_01995 1.2e-132 479.2 Lactobacillaceae Bacteria 1TP76@1239,3F4RI@33958,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase gnl|extdb|FAM1079-i1-1.1_002140 1071400.LBUCD034_2022 1.1e-07 62.0 Lactobacillaceae ydcZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 2.A.7.21 Bacteria 1V0FB@1239,3F4R4@33958,4HFG7@91061,COG3238@1,COG3238@2 NA|NA|NA S Putative inner membrane exporter, YdcZ gnl|extdb|FAM1079-i1-1.1_002142 1423743.JCM14108_1201 3.5e-73 281.2 Lactobacillaceae speG ko:K07023 ko00000 Bacteria 1V3W1@1239,3F6G6@33958,4HH6A@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_002143 568703.LGG_01349 3e-39 167.9 Lactobacillaceae rmeD ko:K13640 ko00000,ko03000 Bacteria 1VB69@1239,3FC69@33958,4HN6R@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance gnl|extdb|FAM1079-i1-1.1_002144 1423734.JCM14202_437 3.8e-47 194.1 Lactobacillaceae 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1V78I@1239,3F5I2@33958,4HKFY@91061,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family gnl|extdb|FAM1079-i1-1.1_002145 1423734.JCM14202_436 1.4e-69 269.6 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3F74B@33958,4HC4I@91061,COG0846@1,COG0846@2 NA|NA|NA K Sir2 family gnl|extdb|FAM1079-i1-1.1_002146 1231336.L248_2169 3.7e-60 238.0 Lactobacillaceae ydeA Bacteria 1V1Z0@1239,3FBK4@33958,4IQYN@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family gnl|extdb|FAM1079-i1-1.1_002147 1071400.LBUCD034_0648 5e-41 174.9 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VZE5@1239,3F832@33958,4HYX4@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM1079-i1-1.1_002150 797515.HMPREF9103_01362 6.4e-165 586.6 Lactobacillaceae Bacteria 1U5QV@1239,29PC0@1,309UH@2,3F6BY@33958,4IFEY@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002153 797515.HMPREF9103_01358 1.7e-265 921.4 Lactobacillaceae Bacteria 1UYJN@1239,3FBEE@33958,4HF8I@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic gnl|extdb|FAM1079-i1-1.1_002114 797515.HMPREF9103_00661 4.6e-216 756.9 Lactobacillaceae argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase gnl|extdb|FAM1079-i1-1.1_002129 1071400.LBUCD034_2022 2.3e-141 508.4 Lactobacillaceae ydcZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 2.A.7.21 Bacteria 1V0FB@1239,3F4R4@33958,4HFG7@91061,COG3238@1,COG3238@2 NA|NA|NA S Putative inner membrane exporter, YdcZ gnl|extdb|FAM1079-i1-1.1_002151 797515.HMPREF9103_01361 9.2e-194 682.9 Lactobacillaceae Bacteria 1U7CX@1239,3F9E4@33958,4IH8G@91061,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein gnl|extdb|FAM1079-i1-1.1_002154 575594.ACOH01000016_gene1565 1e-10 71.2 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_002155 411465.PEPMIC_00655 1.2e-14 87.0 Firmicutes Bacteria 1VI7J@1239,2E6BM@1,330ZD@2 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002157 1423743.JCM14108_2747 2.3e-208 731.5 Lactobacillaceae argE 3.5.1.16 ko:K01438,ko:K20895 ko00220,ko00730,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00730,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107,R11313 RC00064,RC00197,RC00300 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQS9@1239,3F5FM@33958,4HBWM@91061,COG0624@1,COG0624@2 NA|NA|NA E Acetylornithine deacetylase gnl|extdb|FAM1079-i1-1.1_002158 797515.HMPREF9103_02082 0.0 1290.4 Lactobacillaceae Bacteria 1U7C7@1239,3F9C4@33958,4IH7I@91061,COG4934@1,COG4934@2 NA|NA|NA O collagen metabolic process gnl|extdb|FAM1079-i1-1.1_002159 1423780.LOT_1834 3.9e-18 98.2 Lactobacillaceae Bacteria 1U6TF@1239,29Z5R@1,30M3H@2,3F8GI@33958,4IGM8@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002160 797515.HMPREF9103_02084 2.7e-282 977.2 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol gnl|extdb|FAM1079-i1-1.1_002161 797515.HMPREF9103_02086 1.9e-281 974.5 Lactobacillaceae chaT1 ko:K03446 M00701 ko00000,ko00002,ko02000 2.A.1.3 Bacteria 1VRVX@1239,3F4T2@33958,4HV95@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002162 797515.HMPREF9103_02087 6.3e-168 596.7 Lactobacillaceae 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F3WU@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase gnl|extdb|FAM1079-i1-1.1_002163 797515.HMPREF9103_02088 1.1e-149 535.8 Lactobacillaceae mtnU 3.5.1.3 ko:K11206,ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 1TQDK@1239,3F4ND@33958,4HC44@91061,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase gnl|extdb|FAM1079-i1-1.1_002164 797515.HMPREF9103_02089 1.7e-163 582.0 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport gnl|extdb|FAM1079-i1-1.1_002165 797515.HMPREF9103_02090 6.9e-300 1035.8 Lactobacillaceae 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F51Y@33958,4HBRJ@91061,COG1070@1,COG1070@2 NA|NA|NA G Carbohydrate kinase, FGGY family protein gnl|extdb|FAM1079-i1-1.1_002166 525309.HMPREF0494_0699 9.1e-128 463.0 Lactobacillaceae Bacteria 1UETI@1239,3F57M@33958,4HB6V@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase gnl|extdb|FAM1079-i1-1.1_002167 797515.HMPREF9103_02094 3.6e-210 737.3 Lactobacillaceae 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRT1@1239,3F5ZK@33958,4HJRA@91061,COG1940@1,COG1940@2 NA|NA|NA GK Winged helix-turn-helix DNA-binding gnl|extdb|FAM1079-i1-1.1_002168 797515.HMPREF9103_02095 4.6e-269 933.3 Lactobacillaceae ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2211@1,COG2211@2 NA|NA|NA G Transporter gnl|extdb|FAM1079-i1-1.1_002169 797515.HMPREF9103_02096 3.6e-60 237.3 Lactobacillaceae ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1VCDB@1239,3FBNS@33958,4IRDS@91061,COG4095@1,COG4095@2 NA|NA|NA S Sugar efflux transporter for intercellular exchange gnl|extdb|FAM1079-i1-1.1_002170 797515.HMPREF9103_02099 3.7e-185 654.1 Lactobacillaceae trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8U@1239,3F50X@33958,4H9KQ@91061,COG0547@1,COG0547@2 NA|NA|NA F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) gnl|extdb|FAM1079-i1-1.1_002171 797515.HMPREF9103_02100 9.5e-133 479.6 Lactobacillaceae trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K01817,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR94@1239,3F5AK@33958,4HDZQ@91061,COG0134@1,COG0134@2 NA|NA|NA E Belongs to the TrpC family gnl|extdb|FAM1079-i1-1.1_002172 797515.HMPREF9103_02101 4.8e-97 360.5 Lactobacillaceae trpF GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24 ko:K01696,ko:K01817,ko:K13498,ko:K22100 ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230 M00023,M00840 R00674,R02340,R02722,R03508,R03509,R11072 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343 ko00000,ko00001,ko00002,ko01000 iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 1V6Y0@1239,3F4B6@33958,4HN68@91061,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family gnl|extdb|FAM1079-i1-1.1_002173 797515.HMPREF9103_02102 5.9e-230 803.1 Lactobacillaceae trpB 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPI3@1239,3F4DT@33958,4H9WC@91061,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine gnl|extdb|FAM1079-i1-1.1_002174 797515.HMPREF9103_02103 4.3e-141 507.3 Lactobacillaceae trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXA@1239,3F50S@33958,4HFQ8@91061,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate gnl|extdb|FAM1079-i1-1.1_002175 797515.HMPREF9103_02104 7.1e-42 176.0 Lactobacillaceae Bacteria 1U6DF@1239,2DKPX@1,30A9S@2,3F7NG@33958,4IG56@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002176 797515.HMPREF9103_02105 3e-282 977.2 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein gnl|extdb|FAM1079-i1-1.1_002177 797515.HMPREF9103_02106 1.9e-100 371.7 Lactobacillaceae rimL ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3F6YW@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_002178 797515.HMPREF9103_02107 5.5e-56 223.4 Lactobacillaceae GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 Bacteria 1VB8K@1239,3F7HF@33958,4HKT7@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) gnl|extdb|FAM1079-i1-1.1_002179 797515.HMPREF9103_02108 1.5e-40 171.8 Bacteria ko:K15773 ko00000,ko02048,ko03000 Bacteria COG1813@1,COG1813@2 NA|NA|NA K peptidyl-tyrosine sulfation gnl|extdb|FAM1079-i1-1.1_002180 797515.HMPREF9103_02110 4.1e-237 827.0 Lactobacillaceae yhjE Bacteria 1TQIJ@1239,3FCBR@33958,4HAM0@91061,COG0477@1,COG0477@2 NA|NA|NA EGP MFS transporter, metabolite H symporter (MHS) family protein gnl|extdb|FAM1079-i1-1.1_002181 797515.HMPREF9103_02111 4.5e-39 166.8 Lactobacillaceae Bacteria 1U6G2@1239,29PDU@1,30AC0@2,3F7U2@33958,4IG83@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002182 1071400.LBUCD034_2359 3.9e-141 508.1 Lactobacillaceae natB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TXRK@1239,3F3KA@33958,4HC9K@91061,COG1668@1,COG1668@2 NA|NA|NA CP ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_002183 797515.HMPREF9103_02114 1.6e-168 598.6 Lactobacillaceae natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR06@1239,3F4J8@33958,4H9RX@91061,COG4152@1,COG4152@2 NA|NA|NA S ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_002185 797515.HMPREF9103_02116 1.9e-42 177.9 Lactobacillaceae ko:K07030 ko00000 Bacteria 1VA0J@1239,3F786@33958,4HPAV@91061,COG1461@1,COG1461@2 NA|NA|NA S Dihydroxyacetone kinase family gnl|extdb|FAM1079-i1-1.1_002186 1423743.JCM14108_1119 2.5e-51 208.0 Lactobacillaceae hxlR Bacteria 1VA9M@1239,3F7S1@33958,4HH0A@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family gnl|extdb|FAM1079-i1-1.1_002187 797515.HMPREF9103_02118 1.9e-80 305.1 Lactobacillaceae Bacteria 1U7WT@1239,29QD9@1,30BCI@2,3FA9R@33958,4IHU5@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002188 797515.HMPREF9103_02119 8.5e-56 222.6 Lactobacillaceae Bacteria 1U87S@1239,29QJN@1,30BJ8@2,3FANF@33958,4II5G@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002189 525318.HMPREF0497_0083 1e-173 616.7 Lactobacillaceae XK27_00765 ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TSZA@1239,28MBB@1,2ZAPV@2,3F4FX@33958,4HDKH@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002190 797515.HMPREF9103_02122 7.6e-143 513.1 Lactobacillaceae ecsA_2 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPMQ@1239,3FC3G@33958,4HA8K@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM1079-i1-1.1_002191 35841.BT1A1_1384 1.2e-29 136.0 Bacillus Bacteria 1TRSF@1239,1ZEH3@1386,4HAYI@91061,COG2826@1,COG2826@2 NA|NA|NA L COG2826 Transposase and inactivated derivatives, IS30 family gnl|extdb|FAM1079-i1-1.1_002192 945021.TEH_01800 2.7e-28 132.1 Enterococcaceae tra Bacteria 1TRSF@1239,4B02V@81852,4HAYI@91061,COG2826@1,COG2826@2 NA|NA|NA L the current gene model (or a revised gene model) may contain a frame shift gnl|extdb|FAM1079-i1-1.1_002193 908339.HMPREF9265_0592 3.5e-161 574.3 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_002194 511437.Lbuc_1944 4.6e-159 567.4 Lactobacillaceae ko:K07133 ko00000 Bacteria 1W7AS@1239,3F9VI@33958,4IHHQ@91061,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) gnl|extdb|FAM1079-i1-1.1_002195 511437.Lbuc_0028 3.1e-147 527.7 Lactobacillaceae tnp2PF3 Bacteria 1VXWA@1239,3F6KZ@33958,4HXG3@91061,COG3293@1,COG3293@2 NA|NA|NA L manually curated gnl|extdb|FAM1079-i1-1.1_002196 1423743.JCM14108_3315 3.1e-87 328.6 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model gnl|extdb|FAM1079-i1-1.1_002198 1231377.C426_1826 8.3e-78 297.4 Bacilli soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,4HCBZ@91061,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein gnl|extdb|FAM1079-i1-1.1_002199 1138822.PL11_10075 2.4e-142 511.9 Bacilli repA Bacteria 1TQXM@1239,2DBC6@1,2Z8BZ@2,4IQUN@91061 NA|NA|NA S Replication initiator protein A (RepA) N-terminus gnl|extdb|FAM1079-i1-1.1_002201 1423734.JCM14202_2806 1.6e-42 178.3 Lactobacillaceae relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F72D@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family gnl|extdb|FAM1079-i1-1.1_002202 1122149.BACN01000133_gene193 1.8e-26 124.4 Lactobacillaceae Bacteria 1U6EI@1239,2DKQ6@1,30AAQ@2,3F7QK@33958,4IG69@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002203 701521.PECL_1932 1.7e-117 428.7 Lactobacillaceae Bacteria 1V4U7@1239,3F5H8@33958,4HHGF@91061,COG4185@1,COG4185@2 NA|NA|NA S protein conserved in bacteria gnl|extdb|FAM1079-i1-1.1_002204 1400520.LFAB_17270 9.7e-40 169.1 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002205 1423734.JCM14202_2802 4.2e-27 126.7 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002206 1423780.LOT_2221 0.0 1245.3 Lactobacillaceae Bacteria 1VQWC@1239,3F4DP@33958,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA MobL family protein gnl|extdb|FAM1079-i1-1.1_002208 1423816.BACQ01000041_gene1636 1.9e-30 137.9 Lactobacillaceae Bacteria 1U69B@1239,29P8A@1,30A6D@2,3F7CJ@33958,4IG0G@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002209 1400520.LFAB_17305 2.6e-192 677.9 Lactobacillaceae Bacteria 1TQN4@1239,3F5I0@33958,4HKTX@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score gnl|extdb|FAM1079-i1-1.1_002211 1122915.AUGY01000012_gene3813 6.2e-94 351.3 Paenibacillaceae 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,26ZGH@186822,4HWN6@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain gnl|extdb|FAM1079-i1-1.1_002212 913848.AELK01000078_gene1664 2.1e-304 1050.8 Lactobacillaceae hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1TPGZ@1239,3F4HM@33958,4HA1J@91061,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification system gnl|extdb|FAM1079-i1-1.1_002213 913848.AELK01000078_gene1665 0.0 2004.6 Lactobacillaceae 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1TP7S@1239,3F50Q@33958,4HB5A@91061,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification gnl|extdb|FAM1079-i1-1.1_002217 334390.LAF_0673 0.0 1305.4 Lactobacillaceae Bacteria 1UHY6@1239,3FBS3@33958,4ISAK@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein gnl|extdb|FAM1079-i1-1.1_002219 1400520.LFAB_17220 3.4e-106 391.0 Lactobacillaceae Bacteria 1UZM8@1239,3FBG8@33958,4IQ67@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain gnl|extdb|FAM1079-i1-1.1_002220 1400520.LFAB_17215 2e-64 251.5 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1VE0E@1239,3F6KW@33958,4HMFJ@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain gnl|extdb|FAM1079-i1-1.1_002221 1400520.LFAB_17210 5.1e-46 189.9 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1U82Z@1239,3FAGS@33958,4II0D@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain gnl|extdb|FAM1079-i1-1.1_002222 1400520.LFAB_17205 0.0 1198.3 Lactobacillaceae ctpA 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase gnl|extdb|FAM1079-i1-1.1_002223 1234593.ANBY01000014_gene1070 1.6e-08 65.1 Staphylococcaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VERB@1239,4GZV4@90964,4HNP0@91061,COG2608@1,COG2608@2 NA|NA|NA P Chaperone that serves for the intracellular sequestration and transport of Cu( ). Delivers Cu( ) to the copper-exporting P-type ATPase A (CopA) (By similarity) gnl|extdb|FAM1079-i1-1.1_002224 315749.Bcer98_0503 5.4e-68 264.2 Bacillus Bacteria 1TS8Z@1239,1ZB3W@1386,4HC86@91061,COG0745@1,COG0745@2 NA|NA|NA KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain gnl|extdb|FAM1079-i1-1.1_002225 1400520.LFAB_17190 1.7e-61 241.9 Lactobacillaceae Bacteria 1V10X@1239,3F3Z4@33958,4H9UD@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor gnl|extdb|FAM1079-i1-1.1_002226 511437.Lbuc_0028 3.2e-91 341.7 Lactobacillaceae tnp2PF3 Bacteria 1VXWA@1239,3F6KZ@33958,4HXG3@91061,COG3293@1,COG3293@2 NA|NA|NA L manually curated gnl|extdb|FAM1079-i1-1.1_002215 1423815.BACR01000001_gene35 5.6e-10 70.1 Lactobacillaceae uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F3WN@33958,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Belongs to the DNA polymerase type-Y family gnl|extdb|FAM1079-i1-1.1_002228 797515.HMPREF9103_02995 1.3e-34 151.8 Lactobacillaceae Bacteria 1U6EH@1239,2A64B@1,30UWT@2,3F7QI@33958,4IG68@91061 NA|NA|NA S MerR HTH family regulatory protein gnl|extdb|FAM1079-i1-1.1_002229 797515.HMPREF9103_02996 3.1e-71 274.2 Lactobacillaceae Bacteria 1VYUH@1239,2BZ0D@1,3489J@2,3F6GG@33958,4HZBR@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002230 525318.HMPREF0497_1958 2.5e-10 72.4 Lactobacillaceae Bacteria 1U48Z@1239,2EQR3@1,33IAY@2,3F8JT@33958,4IE0B@91061 NA|NA|NA S Protein of unknown function (DUF3278) gnl|extdb|FAM1079-i1-1.1_002231 797515.HMPREF9103_02998 5.8e-32 142.9 Lactobacillaceae ko:K07729 ko00000,ko03000 Bacteria 1VERT@1239,3FCDV@33958,4HNKW@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain gnl|extdb|FAM1079-i1-1.1_002232 797515.HMPREF9103_02999 1.5e-106 392.1 Lactobacillaceae 3.2.2.20 ko:K01246,ko:K06977 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V7GR@1239,3F44B@33958,4HJ11@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase gnl|extdb|FAM1079-i1-1.1_002234 797515.HMPREF9103_03002 1.4e-148 532.3 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F46Z@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil gnl|extdb|FAM1079-i1-1.1_002235 797515.HMPREF9103_03003 1.5e-258 898.3 Lactobacillaceae nox 1.6.3.4 ko:K17869 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase gnl|extdb|FAM1079-i1-1.1_002237 797515.HMPREF9103_03005 5.3e-256 889.8 Lactobacillaceae Bacteria 1W4G9@1239,2FCGI@1,2ZQRU@2,3F4XY@33958,4I16N@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002238 797515.HMPREF9103_03006 1.8e-53 214.9 Lactobacillaceae ybjQ Bacteria 1VADM@1239,3F6YC@33958,4HKGZ@91061,COG0393@1,COG0393@2 NA|NA|NA S Belongs to the UPF0145 family gnl|extdb|FAM1079-i1-1.1_002240 797515.HMPREF9103_03008 2.2e-131 474.9 Lactobacillaceae argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP0N@1239,3F5QN@33958,4HH91@91061,COG0548@1,COG0548@2 NA|NA|NA F Belongs to the acetylglutamate kinase family. ArgB subfamily gnl|extdb|FAM1079-i1-1.1_002241 797515.HMPREF9103_03009 1.6e-224 785.0 Lactobacillaceae argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1783 Bacteria 1TPBP@1239,3F433@33958,4H9TQ@91061,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate gnl|extdb|FAM1079-i1-1.1_002242 797515.HMPREF9103_03010 2.5e-189 667.9 Lactobacillaceae argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190 Bacteria 1TPVI@1239,3F5DZ@33958,4H9YD@91061,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde gnl|extdb|FAM1079-i1-1.1_002243 797515.HMPREF9103_03013 2.1e-249 867.8 Lactobacillaceae metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 1VYCY@1239,3FBSS@33958,4H9X5@91061,COG2873@1,COG2873@2 NA|NA|NA E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol gnl|extdb|FAM1079-i1-1.1_002245 525318.HMPREF0497_1941 2e-114 418.7 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter gnl|extdb|FAM1079-i1-1.1_002246 797515.HMPREF9103_03018 3.2e-75 287.7 Lactobacillaceae Bacteria 1V6P0@1239,3F706@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE gnl|extdb|FAM1079-i1-1.1_002247 797515.HMPREF9103_03019 1.8e-65 255.0 Lactobacillaceae Bacteria 1U76H@1239,29PXQ@1,30AW3@2,3F91C@33958,4IH18@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002248 1231336.L248_1604 3.8e-12 77.0 Bacilli ko:K07729 ko00000,ko03000 Bacteria 1VC4J@1239,4HM8Y@91061,COG1476@1,COG1476@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002249 349519.LCK_00066 3.7e-07 61.6 Leuconostocaceae Bacteria 1U3QP@1239,2DK5N@1,308NI@2,4AYU9@81850,4IDHM@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002251 797515.HMPREF9103_03023 0.0 1176.0 Lactobacillaceae Bacteria 1UVBF@1239,2BFR4@1,329JU@2,3F9CM@33958,4IH7U@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002252 797515.HMPREF9103_03025 1.7e-111 408.7 Lactobacillaceae Bacteria 1V7A7@1239,3F63T@33958,4HIII@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding gnl|extdb|FAM1079-i1-1.1_002253 797515.HMPREF9103_03026 1.5e-138 498.8 Lactobacillaceae Bacteria 1UVU7@1239,3F65I@33958,4I37J@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase gnl|extdb|FAM1079-i1-1.1_002254 797515.HMPREF9103_03027 1.7e-93 348.6 Lactobacillaceae Bacteria 1U6CY@1239,29PB8@1,30A9F@2,3F7MS@33958,4IG4Q@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002255 797515.HMPREF9103_03028 6e-121 440.3 Lactobacillaceae ko:K07090 ko00000 Bacteria 1V75K@1239,3F6BU@33958,4HEE8@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM1079-i1-1.1_002256 797515.HMPREF9103_03029 7.1e-106 389.8 Lactobacillaceae ahpC 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1TQU7@1239,3F50G@33958,4HA2M@91061,COG0450@1,COG0450@2 NA|NA|NA O Peroxiredoxin gnl|extdb|FAM1079-i1-1.1_002257 797515.HMPREF9103_03030 2.6e-65 254.6 Lactobacillaceae Bacteria 1U60Z@1239,29P27@1,30A0D@2,3F6T6@33958,4IFPT@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002258 797515.HMPREF9103_03031 3.4e-32 143.7 Bacilli ygzD ko:K07729 ko00000,ko03000 Bacteria 1VEZ1@1239,4HPXB@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_002259 797515.HMPREF9103_03032 5.9e-52 209.9 Lactobacillaceae pcaC 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1VWSB@1239,3F736@33958,4HJ1V@91061,COG0599@1,COG0599@2 NA|NA|NA S decarboxylase gnl|extdb|FAM1079-i1-1.1_002260 797515.HMPREF9103_03033 2.2e-80 304.7 Lactobacillaceae yphH Bacteria 1V3TP@1239,3FBIJ@33958,4IQRJ@91061,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain gnl|extdb|FAM1079-i1-1.1_002261 1302286.BAOT01000061_gene2075 1.4e-114 419.1 Lactobacillaceae Bacteria 1TRHF@1239,3F3VA@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM1079-i1-1.1_002262 797515.HMPREF9103_03037 1.7e-70 271.9 Lactobacillaceae Bacteria 1VAT0@1239,3FC64@33958,4HKQ1@91061,COG0789@1,COG0789@2 NA|NA|NA K transcriptional regulator, MerR family gnl|extdb|FAM1079-i1-1.1_002263 797515.HMPREF9103_03038 1.1e-75 289.3 Lactobacillaceae Bacteria 1U6VT@1239,29PPR@1,30AMW@2,3F8KB@33958,4IGPV@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002227 797515.HMPREF9103_02994 9.6e-158 562.8 Lactobacillaceae czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,3F4KJ@33958,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter gnl|extdb|FAM1079-i1-1.1_002236 797515.HMPREF9103_03004 2.7e-222 777.7 Lactobacillaceae Bacteria 1U50T@1239,29XME@1,309GD@2,3F3WD@33958,4IESP@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002239 797515.HMPREF9103_03007 1.5e-214 751.9 Lactobacillaceae argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP9S@1239,3F52J@33958,4H9VZ@91061,COG4992@1,COG4992@2 NA|NA|NA E acetylornithine gnl|extdb|FAM1079-i1-1.1_002244 797515.HMPREF9103_03014 8.1e-173 612.8 Lactobacillaceae metAA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11970 Bacteria 1TQVR@1239,3F5CA@33958,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to gnl|extdb|FAM1079-i1-1.1_002264 797515.HMPREF9103_03171 1.3e-154 552.4 Lactobacillaceae hipB GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K15773 ko00000,ko02048,ko03000 Bacteria 1V1KD@1239,3FCE7@33958,4HF5W@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_002265 797515.HMPREF9103_03172 7.8e-105 386.3 Lactobacillaceae Bacteria 1VUSY@1239,2AYWY@1,3354X@2,3FC0S@33958,4HVEY@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002266 1423780.LOT_1651 3.6e-212 744.6 Lactobacillaceae lmrA1 ko:K02021,ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_002267 1423780.LOT_1652 5.8e-263 913.3 Lactobacillaceae lmrA2 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F56U@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region gnl|extdb|FAM1079-i1-1.1_002268 1423780.LOT_1653 1.1e-43 183.0 Lactobacillaceae Bacteria 1TTKD@1239,3F7T9@33958,4HQ62@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002269 1423780.LOT_0739 7.8e-275 952.6 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system gnl|extdb|FAM1079-i1-1.1_002270 797515.HMPREF9103_03175 2.7e-76 291.2 Lactobacillaceae Bacteria 1VWJX@1239,3FBAG@33958,4HWB1@91061,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family gnl|extdb|FAM1079-i1-1.1_002271 797515.HMPREF9103_03176 2e-239 834.7 Lactobacillaceae Bacteria 1TS0Y@1239,3F4GE@33958,4HEMR@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002272 797515.HMPREF9103_03177 1.2e-277 961.8 Lactobacillaceae gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM1079-i1-1.1_002273 797515.HMPREF9103_03178 2.7e-163 581.3 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 Bacteria 1V4PN@1239,3F3Z6@33958,4HHJP@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain gnl|extdb|FAM1079-i1-1.1_002274 797515.HMPREF9103_03179 1.7e-84 318.5 Lactobacillaceae mutT 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1VFYN@1239,3FBDN@33958,4IPPU@91061,COG1051@1,COG1051@2 NA|NA|NA F Belongs to the Nudix hydrolase family gnl|extdb|FAM1079-i1-1.1_002275 525318.HMPREF0497_0596 1.9e-229 801.6 Lactobacillaceae amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1TQYG@1239,3F3X1@33958,4HBGK@91061,COG0004@1,COG0004@2 NA|NA|NA P ammonium transporter gnl|extdb|FAM1079-i1-1.1_002276 797515.HMPREF9103_03182 1.5e-112 412.1 Lactobacillaceae ylbE Bacteria 1TQFS@1239,3F521@33958,4HDA2@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding gnl|extdb|FAM1079-i1-1.1_002277 797515.HMPREF9103_03183 0.0 1148.3 Lactobacillaceae cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3F4T3@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase gnl|extdb|FAM1079-i1-1.1_002278 1138822.PL11_02390 4.2e-25 120.2 Lactobacillaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VFJ8@1239,3F830@33958,4HNY2@91061,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain gnl|extdb|FAM1079-i1-1.1_002279 797515.HMPREF9103_03185 5.5e-95 353.6 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VT55@1239,3FC60@33958,4HU0T@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family gnl|extdb|FAM1079-i1-1.1_002280 797515.HMPREF9103_03186 1e-184 652.5 Lactobacillaceae tas Bacteria 1UKPC@1239,3F5X5@33958,4HCF8@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family gnl|extdb|FAM1079-i1-1.1_002281 797515.HMPREF9103_03188 6.9e-81 306.6 Lactobacillaceae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,3F6P0@33958,4HFR7@91061,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) gnl|extdb|FAM1079-i1-1.1_002282 1423780.LOT_0755 4.7e-189 667.2 Lactobacillaceae purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) gnl|extdb|FAM1079-i1-1.1_002283 797515.HMPREF9103_03191 3.9e-136 490.7 Lactobacillaceae purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 1TP11@1239,3F44Z@33958,4H9U8@91061,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family gnl|extdb|FAM1079-i1-1.1_002284 797515.HMPREF9103_03192 7.5e-42 176.0 Lactobacillaceae purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1VEH1@1239,3F81F@33958,4HP0E@91061,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM1079-i1-1.1_002285 797515.HMPREF9103_03193 1.1e-127 462.6 Lactobacillaceae purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1B@1239,3F48D@33958,4HAKZ@91061,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM1079-i1-1.1_002286 797515.HMPREF9103_03194 0.0 1475.7 Lactobacillaceae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAS@1239,3F4IQ@33958,4HB3N@91061,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL gnl|extdb|FAM1079-i1-1.1_002287 1423780.LOT_0760 3.5e-266 923.7 Lactobacillaceae purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,3F3U7@33958,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine gnl|extdb|FAM1079-i1-1.1_002288 797515.HMPREF9103_03196 1.5e-186 658.7 Lactobacillaceae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1TP9J@1239,3F4RT@33958,4HABW@91061,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase gnl|extdb|FAM1079-i1-1.1_002289 525318.HMPREF0497_0609 5.3e-96 357.1 Lactobacillaceae purN 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3RJ@1239,3F3UN@33958,4HGY5@91061,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate gnl|extdb|FAM1079-i1-1.1_002290 797515.HMPREF9103_03198 2.6e-291 1007.3 Lactobacillaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,3F4FD@33958,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH gnl|extdb|FAM1079-i1-1.1_002291 797515.HMPREF9103_03199 1.2e-238 832.0 Lactobacillaceae purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 1UHN9@1239,3F4Z8@33958,4HA70@91061,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family gnl|extdb|FAM1079-i1-1.1_002292 1423743.JCM14108_2989 1.4e-70 272.7 Lactobacillaceae gph ko:K03292,ko:K05820 ko00000,ko02000 2.A.1.27,2.A.2 Bacteria 1TRA5@1239,3FBC4@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_002293 334390.LAF_0705 1.5e-231 808.5 Lactobacillaceae yagE Bacteria 1VTJD@1239,3FCAK@33958,4HTEM@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease gnl|extdb|FAM1079-i1-1.1_002294 334390.LAF_0704 1.4e-215 755.4 Lactobacillaceae Bacteria 1TRFZ@1239,3F4KN@33958,4HEZ0@91061,COG1808@1,COG1808@2 NA|NA|NA S Domain of unknown function (DUF389) gnl|extdb|FAM1079-i1-1.1_002295 334390.LAF_0703 2.3e-53 214.5 Lactobacillaceae Bacteria 1U6D3@1239,2905K@1,30A9K@2,3F7N1@33958,4IG4V@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002296 525318.HMPREF0497_1779 0.0 1158.7 Lactobacillaceae Bacteria 1TRR1@1239,3FC7P@33958,4HCR9@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO gnl|extdb|FAM1079-i1-1.1_002297 797515.HMPREF9103_00671 7.8e-84 317.0 Lactobacillaceae Bacteria 1UVST@1239,2BFY7@1,329TW@2,3F94Y@33958,4I2BW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002300 797515.HMPREF9103_00675 8.6e-290 1002.3 Lactobacillaceae ybeC Bacteria 1TPJH@1239,3F4AR@33958,4HC13@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid gnl|extdb|FAM1079-i1-1.1_002302 797515.HMPREF9103_00677 2e-88 331.6 Lactobacillaceae guaD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.12,3.5.4.3,3.5.4.33 ko:K01487,ko:K01493,ko:K11991 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00429 R01663,R01676,R10223 RC00074,RC00204,RC00477 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 Bacteria 1V7G0@1239,3F6S6@33958,4HMR9@91061,COG0590@1,COG0590@2 NA|NA|NA FJ MafB19-like deaminase gnl|extdb|FAM1079-i1-1.1_002304 797515.HMPREF9103_00680 1.8e-303 1047.7 Lactobacillaceae cdr 1.8.1.14 ko:K08255 ko00000,ko01000 Bacteria 1TPWW@1239,3FBSF@33958,4HA11@91061,COG0446@1,COG0446@2,COG0607@1,COG0607@2 NA|NA|NA P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gnl|extdb|FAM1079-i1-1.1_002305 797515.HMPREF9103_00681 2e-85 321.6 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F6EQ@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family gnl|extdb|FAM1079-i1-1.1_002306 797515.HMPREF9103_00682 2.7e-96 357.8 Lactobacillaceae yxkA ko:K06910 ko00000 Bacteria 1V88T@1239,3FBBK@33958,4HQ0Q@91061,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein gnl|extdb|FAM1079-i1-1.1_002307 797515.HMPREF9103_00683 2.1e-103 381.7 Lactobacillaceae Bacteria 1U658@1239,29P5E@1,30A3K@2,3F72Z@33958,4IFV1@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002308 797515.HMPREF9103_00684 3e-90 337.8 Lactobacillaceae elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 1VAJY@1239,3F76D@33958,4HIH7@91061,COG2153@1,COG2153@2 NA|NA|NA S (GNAT) family gnl|extdb|FAM1079-i1-1.1_002309 797515.HMPREF9103_00685 1.1e-248 865.5 Lactobacillaceae pyrP ko:K02824 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 iLJ478.TM0819 Bacteria 1TQKX@1239,3F3UJ@33958,4HAEU@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease gnl|extdb|FAM1079-i1-1.1_002310 797515.HMPREF9103_00686 1.1e-86 325.9 Lactobacillaceae Bacteria 1V562@1239,3F9ST@33958,4HMAE@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_002311 797515.HMPREF9103_00687 8e-73 279.6 Lactobacillaceae Bacteria 1U7Q5@1239,29Q90@1,30B83@2,3FA08@33958,4IHMG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002312 797515.HMPREF9103_00688 4.2e-107 394.0 Lactobacillaceae ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 Bacteria 1TRZD@1239,3F6K8@33958,4HC4C@91061,COG0517@1,COG0517@2 NA|NA|NA K Domain in cystathionine beta-synthase and other proteins. gnl|extdb|FAM1079-i1-1.1_002314 797515.HMPREF9103_00690 1.2e-76 292.7 Lactobacillaceae Bacteria 1VF51@1239,3F725@33958,4HM7R@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family gnl|extdb|FAM1079-i1-1.1_002315 797515.HMPREF9103_00692 1.2e-183 649.0 Lactobacillaceae 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_002316 525318.HMPREF0497_1803 2.3e-50 205.3 Lactobacillaceae Bacteria 1V8M5@1239,3F6RT@33958,4HHMT@91061,COG4283@1,COG4283@2 NA|NA|NA S DinB superfamily gnl|extdb|FAM1079-i1-1.1_002317 797515.HMPREF9103_00695 3e-213 747.7 Lactobacillaceae Bacteria 1UHRM@1239,3FBSU@33958,4ISF4@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Transmembrane secretion effector gnl|extdb|FAM1079-i1-1.1_002318 797515.HMPREF9103_00696 1.7e-157 562.0 Lactobacillaceae ropB Bacteria 1VHH9@1239,3F4WA@33958,4HHNF@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_002319 797515.HMPREF9103_00697 1.1e-141 509.2 Lactobacillaceae XK27_08845 ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F3NW@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_002320 797515.HMPREF9103_00698 3.9e-154 550.8 Lactobacillaceae XK27_08840 ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family gnl|extdb|FAM1079-i1-1.1_002321 797515.HMPREF9103_00699 1.7e-182 645.2 Lactobacillaceae ABC-SBP ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter gnl|extdb|FAM1079-i1-1.1_002299 797515.HMPREF9103_00674 6.2e-70 270.0 Lactobacillaceae Bacteria 1U7SR@1239,29PW3@1,319WP@2,3FA4E@33958,4IHQ7@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002303 797515.HMPREF9103_00678 4.1e-229 800.4 Lactobacillaceae ko:K03458 ko00000 2.A.40 Bacteria 1TNZZ@1239,3FC8X@33958,4HCX6@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease gnl|extdb|FAM1079-i1-1.1_002313 797515.HMPREF9103_00689 0.0 1739.2 Lactobacillaceae ppdK 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPK8@1239,3FBUR@33958,4HBU2@91061,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Belongs to the PEP-utilizing enzyme family gnl|extdb|FAM1079-i1-1.1_002322 797515.HMPREF9103_00701 2.1e-135 488.4 Lactobacillaceae tcyA ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 Bacteria 1TR13@1239,3F4MH@33958,4HBRP@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family gnl|extdb|FAM1079-i1-1.1_002323 797515.HMPREF9103_01616 1.3e-75 288.9 Lactobacillaceae ko:K04750 ko00000 Bacteria 1V6QS@1239,3F6RM@33958,4HK80@91061,COG2764@1,COG2764@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase gnl|extdb|FAM1079-i1-1.1_002324 797515.HMPREF9103_01617 6.4e-146 523.5 Lactobacillaceae 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 R05066 RC00099 ko00000,ko00001,ko01000 Bacteria 1U5HC@1239,3F5Y9@33958,4IF86@91061,COG2084@1,COG2084@2 NA|NA|NA I NAD binding domain of 6-phosphogluconate dehydrogenase gnl|extdb|FAM1079-i1-1.1_002325 797515.HMPREF9103_01618 1.2e-120 439.1 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1U5PG@1239,3F69M@33958,4IFDX@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase gnl|extdb|FAM1079-i1-1.1_002326 797515.HMPREF9103_01619 3.4e-64 250.8 Lactobacillaceae yeaO Bacteria 1VABH@1239,3F715@33958,4HKI2@91061,COG3189@1,COG3189@2 NA|NA|NA S Protein of unknown function, DUF488 gnl|extdb|FAM1079-i1-1.1_002327 525318.HMPREF0497_1694 5.5e-99 367.1 Lactobacillaceae mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1E6@1239,3FC7N@33958,4HJ10@91061,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family gnl|extdb|FAM1079-i1-1.1_002328 797515.HMPREF9103_01621 2.5e-86 324.7 Lactobacillaceae pgpA 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 1V3I0@1239,3F6QT@33958,4HH4Y@91061,COG1267@1,COG1267@2 NA|NA|NA I Phosphatidylglycerophosphatase A gnl|extdb|FAM1079-i1-1.1_002329 797515.HMPREF9103_01622 9.7e-149 532.7 Lactobacillaceae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1TQC1@1239,3F3MK@33958,4H9S9@91061,COG0024@1,COG0024@2 NA|NA|NA E Methionine Aminopeptidase gnl|extdb|FAM1079-i1-1.1_002330 797515.HMPREF9103_01627 9.1e-149 533.1 Lactobacillaceae glcK 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKW@1239,3F50I@33958,4HGCA@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family gnl|extdb|FAM1079-i1-1.1_002331 797515.HMPREF9103_01628 5.1e-41 173.3 Bacteria ko:K15773 ko00000,ko02048,ko03000 Bacteria COG1813@1,COG1813@2 NA|NA|NA K peptidyl-tyrosine sulfation gnl|extdb|FAM1079-i1-1.1_002332 797515.HMPREF9103_01629 0.0 1331.6 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 gnl|extdb|FAM1079-i1-1.1_002333 797515.HMPREF9103_01630 5.8e-174 616.7 Lactobacillaceae Bacteria 1TQQR@1239,3FBA4@33958,4HHU5@91061,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) gnl|extdb|FAM1079-i1-1.1_002334 797515.HMPREF9103_01631 1.1e-56 225.7 Lactobacillaceae XK27_02560 ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1VX9Z@1239,3F7Q5@33958,4HXCM@91061,COG2151@1,COG2151@2 NA|NA|NA S Pfam:DUF59 gnl|extdb|FAM1079-i1-1.1_002335 797515.HMPREF9103_01632 0.0 1146.7 Lactobacillaceae ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1R@1239,3F45Q@33958,4H9ZG@91061,COG0129@1,COG0129@2 NA|NA|NA EG Belongs to the IlvD Edd family gnl|extdb|FAM1079-i1-1.1_002336 797515.HMPREF9103_01633 4e-56 223.8 Lactobacillaceae Bacteria 1U6F2@1239,29PCD@1,30AB4@2,3F7S2@33958,4IG6W@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002337 797515.HMPREF9103_01634 5.4e-253 879.8 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3NB@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA gnl|extdb|FAM1079-i1-1.1_002338 525318.HMPREF0497_1705 2.9e-29 134.0 Lactobacillaceae Bacteria 1U6TC@1239,2C9Z9@1,30AK9@2,3F8GF@33958,4IGM5@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002339 525318.HMPREF0497_1706 4.5e-100 370.9 Lactobacillaceae MA20_01715 ko:K07090 ko00000 Bacteria 1V46C@1239,3F501@33958,4HGYI@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein gnl|extdb|FAM1079-i1-1.1_002340 797515.HMPREF9103_01639 5.7e-39 166.4 Lactobacillaceae Bacteria 1U82V@1239,29QGX@1,30BGB@2,3FAGN@33958,4II09@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002341 797515.HMPREF9103_01640 2.6e-100 371.3 Lactobacillaceae ydcN GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 Bacteria 1V1K5@1239,3F5FE@33958,4HGGY@91061,COG1396@1,COG1396@2,COG1917@1,COG1917@2 NA|NA|NA K Cupin domain gnl|extdb|FAM1079-i1-1.1_002342 797515.HMPREF9103_01641 4.6e-118 430.6 Lactobacillaceae azlC Bacteria 1U49T@1239,3F45S@33958,4HDIJ@91061,COG1296@1,COG1296@2 NA|NA|NA E branched-chain amino acid gnl|extdb|FAM1079-i1-1.1_002343 797515.HMPREF9103_01642 1e-48 199.1 Lactobacillaceae azlD Bacteria 1VCZD@1239,3FB5H@33958,4HP7I@91061,COG4392@1,COG4392@2 NA|NA|NA S Branched-chain amino acid transport protein (AzlD) gnl|extdb|FAM1079-i1-1.1_002344 797515.HMPREF9103_01643 6.6e-60 236.5 Lactobacillaceae Bacteria 1U6EE@1239,29PCD@1,30AAM@2,3F7QF@33958,4IG66@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002345 797515.HMPREF9103_01645 0.0 1434.9 Lactobacillaceae pmpD Bacteria 1UN2V@1239,3FBY9@33958,4IU5R@91061,COG3210@1,COG3210@2 NA|NA|NA U Parallel beta-helix repeats gnl|extdb|FAM1079-i1-1.1_002346 797515.HMPREF9103_01646 5.5e-80 303.5 Lactobacillaceae yycN 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1VAU8@1239,3F7PM@33958,4HMA6@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_002348 797515.HMPREF9103_01648 1e-183 649.4 Lactobacillaceae dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase gnl|extdb|FAM1079-i1-1.1_002349 797515.HMPREF9103_01649 1.1e-69 269.2 Lactobacillaceae usp Bacteria 1U425@1239,3F6XU@33958,4I3ZI@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family gnl|extdb|FAM1079-i1-1.1_002351 1423732.BALS01000006_gene626 1.2e-50 206.8 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VMES@1239,2EGU7@1,33AKD@2,3F7PT@33958,4HXVU@91061 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_002352 543734.LCABL_14290 8.4e-104 383.6 Lactobacillaceae bcrA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBQ@1239,3FC3R@33958,4HAGA@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM1079-i1-1.1_002353 1423732.BALS01000006_gene629 3.5e-75 288.1 Lactobacillaceae Bacteria 1UYA6@1239,3F6RJ@33958,4IQ4T@91061,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal gnl|extdb|FAM1079-i1-1.1_002354 543734.LCABL_14270 6.3e-72 277.7 Lactobacillaceae Bacteria 1UZKD@1239,3FBXA@33958,4ITNE@91061,COG0642@1,COG2205@2 NA|NA|NA T GHKL domain gnl|extdb|FAM1079-i1-1.1_002347 797515.HMPREF9103_01647 1.2e-60 239.2 Lactobacillaceae ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria 1V3S2@1239,3F6A3@33958,4HJ0Z@91061,COG1607@1,COG1607@2 NA|NA|NA I Thioesterase superfamily gnl|extdb|FAM1079-i1-1.1_002356 591167.Sfla_6373 1.5e-78 299.7 Actinobacteria Bacteria 2GRRV@201174,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family gnl|extdb|FAM1079-i1-1.1_002357 797515.HMPREF9103_00752 9.4e-277 959.1 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UG1C@1239,3F3SZ@33958,4HCPQ@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C phosphodiesterase gnl|extdb|FAM1079-i1-1.1_002358 797515.HMPREF9103_00753 2.8e-111 407.9 Lactobacillaceae Bacteria 1U61A@1239,2CM3T@1,30A0N@2,3F6TQ@33958,4IFQ4@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002359 797515.HMPREF9103_00754 2e-174 618.2 Lactobacillaceae Bacteria 1TPGD@1239,3F5P3@33958,4HE52@91061,COG4189@1,COG4189@2 NA|NA|NA K transcriptional regulator, ArsR family gnl|extdb|FAM1079-i1-1.1_002360 797515.HMPREF9103_00755 3.8e-203 713.8 Lactobacillaceae abf Bacteria 1TRHI@1239,3F5DX@33958,4H9PB@91061,COG3940@1,COG3940@2 NA|NA|NA G Belongs to the glycosyl hydrolase 43 family gnl|extdb|FAM1079-i1-1.1_002361 797515.HMPREF9103_00756 2.2e-232 811.2 Lactobacillaceae lacY ko:K02532 ko00000,ko02000 2.A.1.5 Bacteria 1UPQ3@1239,3F4IM@33958,4HCKU@91061,COG2211@1,COG2211@2 NA|NA|NA G Oligosaccharide H symporter gnl|extdb|FAM1079-i1-1.1_002362 797515.HMPREF9103_00757 3.1e-170 604.4 Lactobacillaceae Bacteria 1TPUW@1239,3F5JP@33958,4HDIE@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM1079-i1-1.1_002363 797515.HMPREF9103_00758 2e-307 1060.8 Lactobacillaceae Bacteria 1TQ6G@1239,3F4DW@33958,4HC54@91061,COG1574@1,COG1574@2 NA|NA|NA S amidohydrolase gnl|extdb|FAM1079-i1-1.1_002364 797515.HMPREF9103_00759 6.1e-145 520.0 Lactobacillaceae 2.1.1.144,2.1.1.197 ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 Bacteria 1V188@1239,3F8N5@33958,4HENY@91061,COG4106@1,COG4106@2 NA|NA|NA S Methyltransferase type 11 gnl|extdb|FAM1079-i1-1.1_002365 797515.HMPREF9103_00760 6.7e-231 806.2 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) gnl|extdb|FAM1079-i1-1.1_002366 797515.HMPREF9103_00761 4.3e-64 250.4 Lactobacillaceae Bacteria 1U69Q@1239,3F7DU@33958,4IG0V@91061,COG5294@1,COG5294@2 NA|NA|NA S Protein of unknown function (DUF1093) gnl|extdb|FAM1079-i1-1.1_002368 797515.HMPREF9103_00763 3.2e-121 441.0 Lactobacillaceae XK27_07075 ko:K07052 ko00000 Bacteria 1VK3Z@1239,3FC50@33958,4HQGZ@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity gnl|extdb|FAM1079-i1-1.1_002369 797515.HMPREF9103_00764 6.9e-59 233.0 Lactobacillaceae Bacteria 1U5ZX@1239,3F6S4@33958,4IFNX@91061,COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity gnl|extdb|FAM1079-i1-1.1_002371 797515.HMPREF9103_00766 3.2e-33 147.1 Lactobacillaceae Bacteria 1U7FZ@1239,29Q4A@1,30B30@2,3F9KC@33958,4IHC1@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002372 797515.HMPREF9103_00766 1.9e-230 805.1 Lactobacillaceae Bacteria 1U7FZ@1239,29Q4A@1,30B30@2,3F9KC@33958,4IHC1@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002373 1071400.LBUCD034_1943 2.1e-252 877.9 Lactobacillaceae ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 1TRA5@1239,3F3UZ@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_002374 797515.HMPREF9103_00769 2.8e-274 950.7 Lactobacillaceae gtfA 2.4.1.7 ko:K00690 ko00500,map00500 R00803 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1TR93@1239,3F3YR@33958,4HEKC@91061,COG0366@1,COG0366@2 NA|NA|NA G Sucrose glucosyltransferase gnl|extdb|FAM1079-i1-1.1_002375 797515.HMPREF9103_00770 0.0 1133.2 Lactobacillaceae malL 3.2.1.10,3.2.1.20,3.2.1.41 ko:K01182,ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 R00028,R00801,R00802,R01718,R01791,R02111,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 CBM48,GH13,GH31 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein gnl|extdb|FAM1079-i1-1.1_002376 511437.Lbuc_1853 1.5e-159 568.9 Lactobacillaceae scrR ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4JE@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family gnl|extdb|FAM1079-i1-1.1_002377 797515.HMPREF9103_00773 2e-68 265.0 Lactobacillaceae Bacteria 1U69V@1239,2C2U7@1,30A6Y@2,3F7ED@33958,4IG12@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002378 797515.HMPREF9103_00774 1e-153 549.3 Firmicutes rhaS8 Bacteria 1UN2P@1239,COG4977@1,COG4977@2 NA|NA|NA K AraC-like ligand binding domain gnl|extdb|FAM1079-i1-1.1_002379 797515.HMPREF9103_00995 1.2e-282 978.4 Lactobacillaceae araA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 R01761 RC00516 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060 Bacteria 1TPXC@1239,3F878@33958,4HAWS@91061,COG2160@1,COG2160@2 NA|NA|NA G Catalyzes the conversion of L-arabinose to L-ribulose gnl|extdb|FAM1079-i1-1.1_002380 797515.HMPREF9103_00994 8.6e-45 186.4 Lactobacillaceae Bacteria 1U614@1239,29P2C@1,30A0I@2,3F6TE@33958,4IFPX@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002370 797515.HMPREF9103_00765 5.7e-291 1006.1 Lactobacillaceae ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_002381 1114972.AUAW01000022_gene1268 5.4e-48 198.0 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_002382 1114972.AUAW01000022_gene1269 7.4e-58 230.7 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_002383 1114972.AUAW01000022_gene1269 4.9e-57 228.0 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein gnl|extdb|FAM1079-i1-1.1_002384 904293.HMPREF9176_0969 2.7e-21 109.0 Bacilli Bacteria 1W1AX@1239,4HY0T@91061,COG1476@1,COG1476@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain gnl|extdb|FAM1079-i1-1.1_002385 797515.HMPREF9103_02082 3.6e-165 588.6 Lactobacillaceae Bacteria 1U7C7@1239,3F9C4@33958,4IH7I@91061,COG4934@1,COG4934@2 NA|NA|NA O collagen metabolic process gnl|extdb|FAM1079-i1-1.1_002386 1423780.LOT_1043 7e-37 160.2 Lactobacillaceae yjdF Bacteria 1V2J3@1239,28NY7@1,2ZBVG@2,3F6EY@33958,4HMY0@91061 NA|NA|NA S Protein of unknown function (DUF2992) gnl|extdb|FAM1079-i1-1.1_002387 203123.OEOE_1827 2.2e-79 302.4 Leuconostocaceae Bacteria 1U3PB@1239,4AXR5@81850,4HB4W@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family gnl|extdb|FAM1079-i1-1.1_002388 326425.lhe_0302 3.7e-52 211.1 Lactobacillaceae Bacteria 1V5XZ@1239,3FCAY@33958,4HHN5@91061,COG0537@1,COG0537@2 NA|NA|NA FG adenosine 5'-monophosphoramidase activity gnl|extdb|FAM1079-i1-1.1_002389 1423780.LOT_0982 0.0 1097.4 Lactobacillaceae 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen gnl|extdb|FAM1079-i1-1.1_002390 797515.HMPREF9103_01328 2.9e-16 90.9 Lactobacillaceae Bacteria 1U6W5@1239,29PQ2@1,30AN7@2,3F8KU@33958,4IGQA@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002391 797515.HMPREF9103_01329 4.6e-28 129.8 Lactobacillaceae Bacteria 1W51D@1239,29A0B@1,2ZX1X@2,3F8Q7@33958,4I0QW@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002392 797515.HMPREF9103_01330 2.9e-48 197.6 Lactobacillaceae Bacteria 1U6MX@1239,2A0ZV@1,30P58@2,3F866@33958,4IGEQ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002393 797515.HMPREF9103_01331 8.3e-114 416.4 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TUDZ@1239,3F4FG@33958,4HCPC@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport gnl|extdb|FAM1079-i1-1.1_002394 797515.HMPREF9103_01332 4e-270 936.8 Lactobacillaceae ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQRP@1239,3FBTE@33958,4IS5S@91061,COG1129@1,COG1129@2 NA|NA|NA G ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_002395 797515.HMPREF9103_01333 7.5e-106 389.8 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V5J6@1239,3FBNX@33958,4HGBR@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC transporter permease gnl|extdb|FAM1079-i1-1.1_002396 797515.HMPREF9103_01334 4.7e-154 550.4 Lactobacillaceae 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UYU8@1239,3FC86@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase gnl|extdb|FAM1079-i1-1.1_002397 797515.HMPREF9103_01335 6.9e-162 576.6 Lactobacillaceae pva3 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F3RA@33958,4HEQ3@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein gnl|extdb|FAM1079-i1-1.1_002398 797515.HMPREF9103_01336 1.1e-102 379.4 Lactobacillaceae Bacteria 1U55V@1239,29DQI@1,300NC@2,3F4UQ@33958,4IEX6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002400 797515.HMPREF9103_01340 0.0 1260.0 Lactobacillaceae fnq20 1.13.12.16 ko:K00459 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000 Bacteria 1UZ38@1239,3F4ZH@33958,4HDXC@91061,COG4529@1,COG4529@2 NA|NA|NA S FAD-NAD(P)-binding gnl|extdb|FAM1079-i1-1.1_002401 797515.HMPREF9103_01341 1.2e-108 399.1 Lactobacillaceae ddpX GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.13.22 ko:K07282,ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 1VAFK@1239,3F4HX@33958,4HS7K@91061,COG2173@1,COG2173@2 NA|NA|NA E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide gnl|extdb|FAM1079-i1-1.1_002402 797515.HMPREF9103_01342 2.1e-117 428.3 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1V9F4@1239,3F5N4@33958,4IS4H@91061,COG0062@1,COG0062@2 NA|NA|NA H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX gnl|extdb|FAM1079-i1-1.1_002403 797515.HMPREF9103_01343 1.2e-52 212.2 Lactobacillaceae Bacteria 1W304@1239,2905K@1,2ZMVG@2,3F7TH@33958,4I0TS@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002405 1423780.LOT_1508 9.9e-34 149.4 Lactobacillaceae Bacteria 1U72S@1239,2DKU2@1,30AT7@2,3F8WF@33958,4IGXB@91061 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE gnl|extdb|FAM1079-i1-1.1_002407 1071400.LBUCD034_2034 1.9e-89 335.1 Bacilli Bacteria 1VXQF@1239,2DW93@1,33Z4M@2,4HX9F@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002408 511437.Lbuc_1942 9.6e-227 792.7 Lactobacillaceae Bacteria 1UYEF@1239,3F3RJ@33958,4HA2D@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002409 1071400.LBUCD034_2032 5e-105 387.1 Lactobacillaceae Bacteria 1VJ93@1239,3FBB9@33958,4HWSB@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family gnl|extdb|FAM1079-i1-1.1_002399 797515.HMPREF9103_01339 3.6e-300 1036.9 Lactobacillaceae Bacteria 1U7C7@1239,3F9C4@33958,4IH7I@91061,COG4934@1,COG4934@2 NA|NA|NA O collagen metabolic process gnl|extdb|FAM1079-i1-1.1_002406 1423780.LOT_1507 1.2e-30 138.7 Lactobacillaceae Bacteria 1TU4X@1239,3F91Q@33958,4IGM4@91061,COG2161@1,COG2161@2 NA|NA|NA D toxin-antitoxin pair type II binding gnl|extdb|FAM1079-i1-1.1_002410 797515.HMPREF9103_02123 4.8e-179 633.6 Lactobacillaceae 1.8.5.7 ko:K07393 ko00000,ko01000 Bacteria 1TQXQ@1239,3F59U@33958,4H9VF@91061,COG0435@1,COG0435@2 NA|NA|NA O Glutathione S-transferase, N-terminal domain gnl|extdb|FAM1079-i1-1.1_002411 1423806.JCM15457_551 1.2e-13 83.6 Lactobacillaceae Bacteria 1UMMN@1239,3FBH9@33958,4IQJD@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_002413 797515.HMPREF9103_02131 4.5e-120 437.2 Lactobacillaceae ywnB ko:K07118 ko00000 Bacteria 1V546@1239,3FBPM@33958,4IRQD@91061,COG2910@1,COG2910@2 NA|NA|NA S NAD(P)H-binding gnl|extdb|FAM1079-i1-1.1_002414 525318.HMPREF0497_0785 7.9e-84 317.4 Lactobacillaceae ko:K02529 ko00000,ko03000 Bacteria 1TRFH@1239,3F5CG@33958,4HBNT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family gnl|extdb|FAM1079-i1-1.1_002415 1123284.KB899056_gene1027 1.4e-229 802.4 Bacilli 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G COG0366 Glycosidases gnl|extdb|FAM1079-i1-1.1_002417 797515.HMPREF9103_02132 0.0 1538.1 Lactobacillaceae mapA 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 R01555 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic gnl|extdb|FAM1079-i1-1.1_002418 797515.HMPREF9103_02133 2.4e-256 891.0 Lactobacillaceae malT ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM1079-i1-1.1_002419 1423780.LOT_1862 9.6e-158 562.8 Lactobacillaceae scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,3F3K8@33958,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family gnl|extdb|FAM1079-i1-1.1_002420 797515.HMPREF9103_02136 1.6e-188 665.2 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3FC45@33958,4HUHH@91061,COG1063@1,COG1063@2 NA|NA|NA C chlorophyll synthesis pathway protein BchC gnl|extdb|FAM1079-i1-1.1_002421 1423743.JCM14108_1149 1.4e-115 422.5 Lactobacillaceae Bacteria 1VSZX@1239,3F4ZU@33958,4HTJ1@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane gnl|extdb|FAM1079-i1-1.1_002422 797515.HMPREF9103_02139 9.7e-70 269.2 Lactobacillaceae 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1V7XP@1239,3F679@33958,4HXCD@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase gnl|extdb|FAM1079-i1-1.1_002423 797515.HMPREF9103_02140 6.6e-259 899.4 Lactobacillaceae pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iLJ478.TM1385 Bacteria 1TP29@1239,3F3XK@33958,4H9VI@91061,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family gnl|extdb|FAM1079-i1-1.1_002424 797515.HMPREF9103_02142 7.8e-188 662.9 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3FC45@33958,4HUHH@91061,COG1063@1,COG1063@2 NA|NA|NA C chlorophyll synthesis pathway protein BchC gnl|extdb|FAM1079-i1-1.1_002425 797515.HMPREF9103_02143 5.2e-136 490.3 Lactobacillaceae Bacteria 1VSZX@1239,3F4ZU@33958,4HTJ1@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane gnl|extdb|FAM1079-i1-1.1_002426 797515.HMPREF9103_02144 4.3e-70 270.4 Lactobacillaceae 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1V7XP@1239,3F679@33958,4HXCD@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase gnl|extdb|FAM1079-i1-1.1_002427 797515.HMPREF9103_02145 1.2e-277 961.8 Lactobacillaceae nadB 1.3.5.4,1.4.3.16 ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 iJN678.nadB,iSbBS512_1146.nadB Bacteria 1UHSP@1239,3FBYA@33958,4H9ZZ@91061,COG0029@1,COG0029@2 NA|NA|NA H L-aspartate oxidase gnl|extdb|FAM1079-i1-1.1_002428 797515.HMPREF9103_02146 8.4e-212 742.7 Lactobacillaceae nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6R@1239,3F5Z6@33958,4H9QG@91061,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate gnl|extdb|FAM1079-i1-1.1_002429 797515.HMPREF9103_02147 5e-196 690.3 Lactobacillaceae nifS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TPYU@1239,3F5C7@33958,4HA5J@91061,COG1104@1,COG1104@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family gnl|extdb|FAM1079-i1-1.1_002430 797515.HMPREF9103_02148 2.5e-258 897.5 Lactobacillaceae pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iLJ478.TM1385 Bacteria 1TP29@1239,3F3XK@33958,4H9VI@91061,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family gnl|extdb|FAM1079-i1-1.1_002432 1423780.LOT_0933 1e-31 142.5 Lactobacillaceae Bacteria 1U8IZ@1239,29QRX@1,30BRS@2,3FB1E@33958,4IIGZ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002434 1423780.LOT_1625 9e-20 102.4 Lactobacillaceae Bacteria 1U74X@1239,29PWM@1,30AUZ@2,3F8ZC@33958,4IGZK@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002433 1423780.LOT_0934 3.9e-39 167.2 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1U5SS@1239,3F770@33958,4HYAD@91061,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system gnl|extdb|FAM1079-i1-1.1_002437 797515.HMPREF9103_01686 4.1e-150 537.3 Lactobacillaceae cbiQ ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iSB619.SA_RS14165 Bacteria 1TPMV@1239,3F3Y9@33958,4HBTW@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport gnl|extdb|FAM1079-i1-1.1_002438 797515.HMPREF9103_01687 0.0 1117.1 Lactobacillaceae 3.6.3.24 ko:K02031,ko:K02032,ko:K10824,ko:K15587,ko:K16786,ko:K16787 ko02010,ko02024,map02010,map02024 M00239,M00440,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.5 Bacteria 1VRD0@1239,3FBXM@33958,4ISFN@91061,COG1123@1,COG4172@2 NA|NA|NA P ATP-binding cassette cobalt transporter gnl|extdb|FAM1079-i1-1.1_002439 797515.HMPREF9103_01688 1.2e-97 362.5 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V1GT@1239,3F5A7@33958,4HGAE@91061,COG4720@1,COG4720@2 NA|NA|NA S UPF0397 protein gnl|extdb|FAM1079-i1-1.1_002442 511437.Lbuc_0210 2.8e-52 211.5 Lactobacillaceae 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1VGCW@1239,3F6WB@33958,4HQKH@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_002443 797515.HMPREF9103_01693 1.5e-106 392.1 Lactobacillaceae yvdD 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1UKED@1239,3F5U4@33958,4HE2X@91061,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family gnl|extdb|FAM1079-i1-1.1_002444 1071400.LBUCD034_0249 0.0 1277.7 Lactobacillaceae Bacteria 1UKTQ@1239,3F5BP@33958,4HEXZ@91061,COG5520@1,COG5520@2 NA|NA|NA M Glycosyl hydrolase family 59 gnl|extdb|FAM1079-i1-1.1_002445 1071400.LBUCD034_0248 0.0 1090.9 Lactobacillaceae uidA 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDC@1239,3F4FZ@33958,4HCXR@91061,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family gnl|extdb|FAM1079-i1-1.1_002446 568703.LGG_02432 1.6e-253 881.7 Lactobacillaceae ko:K03292,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.5 Bacteria 1U037@1239,3F4MV@33958,4HBZK@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_002447 797515.HMPREF9103_01400 1.6e-177 628.6 Lactobacillaceae rhaR Bacteria 1V1RQ@1239,3FBFV@33958,4IQ5J@91061,COG0662@1,COG0662@2,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein gnl|extdb|FAM1079-i1-1.1_002448 1071400.LBUCD034_2213 0.0 1271.1 Lactobacillaceae 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria 1TSVY@1239,3F4M6@33958,4HWSX@91061,COG3408@1,COG3408@2 NA|NA|NA G Bacterial alpha-L-rhamnosidase concanavalin-like domain gnl|extdb|FAM1079-i1-1.1_002449 67356.KL575637_gene5410 7.9e-36 159.5 Actinobacteria Bacteria 2IE1F@201174,COG1874@1,COG1874@2 NA|NA|NA G Beta-galactosidase gnl|extdb|FAM1079-i1-1.1_002450 1423780.LOT_1448 3.9e-303 1047.0 Lactobacillaceae Bacteria 1TZSZ@1239,2DB7A@1,2Z7KK@2,3F5CP@33958,4HFM6@91061 NA|NA|NA S Glycosyl hydrolase family 115 gnl|extdb|FAM1079-i1-1.1_002451 797515.HMPREF9103_00580 1.3e-55 222.2 Lactobacillaceae Bacteria 1U6EE@1239,29PCD@1,30AAM@2,3F7QF@33958,4IG66@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002452 1423780.LOT_1451 3.6e-280 970.3 Lactobacillaceae ko:K03292,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.5 Bacteria 1U037@1239,3F4MV@33958,4HBZK@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_002453 797515.HMPREF9103_00577 1.9e-118 432.2 Lactobacillaceae Bacteria 1UX6U@1239,3F6PR@33958,4IFMF@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein gnl|extdb|FAM1079-i1-1.1_002454 797515.HMPREF9103_00576 1.2e-183 649.0 Lactobacillaceae ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002441 525318.HMPREF0497_0409 9.9e-154 549.7 Lactobacillaceae pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,3F4DR@33958,4HAT7@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain gnl|extdb|FAM1079-i1-1.1_002456 1114972.AUAW01000027_gene720 1.3e-08 64.3 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_002457 797515.HMPREF9103_02066 2.7e-213 747.7 Lactobacillaceae metC1 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine gnl|extdb|FAM1079-i1-1.1_002458 797515.HMPREF9103_02067 5e-104 383.6 Lactobacillaceae yciB Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG gnl|extdb|FAM1079-i1-1.1_002459 797515.HMPREF9103_02068 0.0 2437.9 Lactobacillaceae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,3F3Z0@33958,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A gnl|extdb|FAM1079-i1-1.1_002460 797515.HMPREF9103_02069 0.0 2327.4 Lactobacillaceae rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.3,3.6.4.12 ko:K01153,ko:K16899 ko00000,ko01000,ko02048,ko03400 Bacteria 1TQJW@1239,3F3RS@33958,4HAY6@91061,COG3857@1,COG3857@2 NA|NA|NA L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity gnl|extdb|FAM1079-i1-1.1_002461 797515.HMPREF9103_02070 1.7e-60 238.4 Lactobacillaceae Bacteria 1U5YA@1239,2C84C@1,309YS@2,3F6PS@33958,4IFMG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002462 797515.HMPREF9103_02071 7.1e-98 363.2 Lactobacillaceae 1.14.14.47,1.6.5.3,1.6.99.3 ko:K00329,ko:K00356,ko:K00491,ko:K21572 ko00190,ko00220,ko00330,ko01100,ko01110,map00190,map00220,map00330,map01100,map01110 R11711,R11712,R11713,R11945 RC00061,RC00177,RC00330,RC01044 ko00000,ko00001,ko01000,ko02000 8.A.46.1,8.A.46.3 Bacteria 1W45J@1239,3F69Y@33958,4I19T@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding gnl|extdb|FAM1079-i1-1.1_002463 797515.HMPREF9103_02072 5.5e-175 620.2 Lactobacillaceae iolS ko:K06607 ko00000,ko01000 Bacteria 1TPIY@1239,3F40K@33958,4HA4Q@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase gnl|extdb|FAM1079-i1-1.1_002464 797515.HMPREF9103_02073 2.5e-89 334.7 Lactobacillaceae yhbO GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006517,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009100,GO:0009266,GO:0009268,GO:0009314,GO:0009408,GO:0009411,GO:0009416,GO:0009438,GO:0009628,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019249,GO:0019538,GO:0019752,GO:0030091,GO:0032787,GO:0033554,GO:0034641,GO:0036211,GO:0036524,GO:0036525,GO:0042180,GO:0042182,GO:0042802,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046394,GO:0046483,GO:0050896,GO:0051596,GO:0051716,GO:0061727,GO:0071704,GO:0072330,GO:0090304,GO:0140096,GO:1901135,GO:1901360,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617 3.5.1.124 ko:K05520 ko00000,ko01000,ko01002 Bacteria 1V3I7@1239,3FC7V@33958,4HFNG@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family gnl|extdb|FAM1079-i1-1.1_002465 797515.HMPREF9103_02074 0.0 1137.9 Lactobacillaceae Bacteria 1V2H3@1239,28PUF@1,2ZCFF@2,3F3KN@33958,4HRKS@91061 NA|NA|NA S TerB-C domain gnl|extdb|FAM1079-i1-1.1_002466 797515.HMPREF9103_02075 5.2e-248 863.2 Lactobacillaceae Bacteria 1TQPH@1239,3F54M@33958,4HCUW@91061,COG1135@1,COG1135@2 NA|NA|NA P P-loop Domain of unknown function (DUF2791) gnl|extdb|FAM1079-i1-1.1_002467 575594.ACOH01000012_gene467 0.0 1259.6 Lactobacillaceae lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 1UHYQ@1239,3F42E@33958,4HD4E@91061,COG1201@1,COG1201@2 NA|NA|NA L DEAD DEAH box helicase gnl|extdb|FAM1079-i1-1.1_002468 797515.HMPREF9103_02078 1.1e-231 808.9 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease gnl|extdb|FAM1079-i1-1.1_002469 1423743.JCM14108_2749 1.1e-76 292.7 Lactobacillaceae ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V22G@1239,3F6CG@33958,4HGG2@91061,COG4708@1,COG4708@2 NA|NA|NA S QueT transporter gnl|extdb|FAM1079-i1-1.1_002470 220668.lp_1771 9.3e-52 210.3 Lactobacillaceae 3.6.3.35 ko:K01990,ko:K02049,ko:K02074,ko:K03546,ko:K09817,ko:K19973 ko02010,map02010 M00188,M00242,M00244,M00254,M00792 ko00000,ko00001,ko00002,ko01000,ko02000,ko03400 3.A.1,3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5,3.A.1.16,3.A.1.17 Bacteria 1U52X@1239,3F47U@33958,4IEUB@91061,COG1121@1,COG1121@2 NA|NA|NA P ATPases associated with a variety of cellular activities gnl|extdb|FAM1079-i1-1.1_002471 1444306.JFZC01000009_gene1912 9.6e-145 520.4 Bacilli Bacteria 1TQQY@1239,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives gnl|extdb|FAM1079-i1-1.1_002472 1267580.AF6_1532 6.7e-14 85.1 Bacilli Bacteria 1VP9D@1239,2EU1C@1,33MIE@2,4I0NG@91061 NA|NA|NA S YcaO cyclodehydratase, ATP-ad Mg2+-binding gnl|extdb|FAM1079-i1-1.1_002473 1267580.AF6_1533 4.1e-30 138.7 Bacilli noxC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.5.1.39 ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1V4TC@1239,4HS69@91061,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase gnl|extdb|FAM1079-i1-1.1_002477 1071400.LBUCD034_1609 6.9e-209 733.0 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family gnl|extdb|FAM1079-i1-1.1_002478 511437.Lbuc_1557 3.2e-119 435.6 Lactobacillaceae Bacteria 1UQFR@1239,29XME@1,3242P@2,3F6IH@33958,4IFI9@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002480 511437.Lbuc_1555 9e-130 469.5 Lactobacillaceae 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1UKTW@1239,3F5AI@33958,4HNDC@91061,COG1974@1,COG1974@2 NA|NA|NA K Peptidase S24-like gnl|extdb|FAM1079-i1-1.1_002481 511437.Lbuc_1554 4.7e-32 143.3 Lactobacillaceae Bacteria 1U7RK@1239,2EV26@1,32FCH@2,3FA2K@33958,4IHNX@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002483 511437.Lbuc_1552 2.1e-28 131.0 Lactobacillaceae Bacteria 1U6BZ@1239,2A5KR@1,30UB8@2,3F7JT@33958,4IG3M@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002486 1071400.LBUCD034_1597 6.4e-59 233.0 Lactobacillaceae Bacteria 1VDBG@1239,3F6R0@33958,4HKZG@91061,COG4707@1,COG4707@2 NA|NA|NA S Domain of unknown function (DUF771) gnl|extdb|FAM1079-i1-1.1_002487 1071400.LBUCD034_1596 2.7e-42 177.6 Lactobacillaceae Bacteria 1U7PA@1239,2BQBH@1,32J6J@2,3F9Z4@33958,4IHKK@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002488 1423780.LOT_2204 2.4e-29 134.0 Lactobacillaceae Bacteria 1U6DV@1239,29PBW@1,30AA3@2,3F7P6@33958,4IG5J@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002489 1423780.LOT_2203 7.9e-34 149.1 Lactobacillaceae Bacteria 1U6D9@1239,2A552@1,30TTU@2,3F7N9@33958,4IG50@91061 NA|NA|NA S YozE SAM-like fold gnl|extdb|FAM1079-i1-1.1_002490 1423743.JCM14108_2663 9.1e-43 179.1 Lactobacillaceae Bacteria 1U6GZ@1239,29PEM@1,30ACT@2,3F7WF@33958,4IG97@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002491 1423780.LOT_2201 8e-133 479.9 Lactobacillaceae Bacteria 1VPW3@1239,2EHDI@1,33B5D@2,3F6I3@33958,4HXEN@91061 NA|NA|NA S Protein of unknown function (DUF1351) gnl|extdb|FAM1079-i1-1.1_002492 1423743.JCM14108_2660 1.2e-126 459.1 Lactobacillaceae Bacteria 1V2PN@1239,28P42@1,2ZBZC@2,3F4QE@33958,4HFRP@91061 NA|NA|NA S AAA domain gnl|extdb|FAM1079-i1-1.1_002493 1423780.LOT_2199 2.7e-260 904.0 Lactobacillaceae res Bacteria 1TQ62@1239,3F3YQ@33958,4HAJ1@91061,COG1061@1,COG1061@2 NA|NA|NA L Helicase C-terminal domain protein gnl|extdb|FAM1079-i1-1.1_002494 1071400.LBUCD034_1591 1.2e-108 399.1 Lactobacillaceae Bacteria 1VATD@1239,2CTNW@1,32STT@2,3F56X@33958,4HPYZ@91061 NA|NA|NA S Protein of unknown function (DUF669) gnl|extdb|FAM1079-i1-1.1_002495 797515.HMPREF9103_02489 0.0 1554.3 Lactobacillaceae ko:K06919 ko00000 Bacteria 1TQP9@1239,3F3UD@33958,4HBTB@91061,COG3378@1,COG3378@2,COG4983@1,COG4983@2 NA|NA|NA S Phage plasmid primase, P4 gnl|extdb|FAM1079-i1-1.1_002497 1071400.LBUCD034_1588 1.3e-67 262.3 Lactobacillaceae Bacteria 1U5U4@1239,29NY6@1,309WA@2,3F6IC@33958,4IFI2@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002499 1423743.JCM14108_2651 4.1e-156 557.4 Lactobacillaceae Bacteria 1U54N@1239,29NJZ@1,309HY@2,3F4NJ@33958,4IEVV@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002500 511437.Lbuc_1529 8.7e-78 296.2 Lactobacillaceae Bacteria 1VFKN@1239,3F87W@33958,4HR16@91061,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases gnl|extdb|FAM1079-i1-1.1_002501 1071400.LBUCD034_1585 6e-91 340.1 Lactobacillaceae Bacteria 1VW7W@1239,3F43B@33958,4HR5B@91061,COG3747@1,COG3747@2 NA|NA|NA L Phage terminase, small subunit gnl|extdb|FAM1079-i1-1.1_002502 797515.HMPREF9103_02435 0.0 1284.2 Lactobacillaceae Bacteria 1TR5W@1239,3FB4K@33958,4HEDC@91061,COG4626@1,COG4626@2 NA|NA|NA S Phage Terminase gnl|extdb|FAM1079-i1-1.1_002503 1423743.JCM14108_2646 1.3e-207 728.8 Lactobacillaceae Bacteria 1UY1R@1239,3FB4N@33958,4HZQS@91061,COG4695@1,COG4695@2 NA|NA|NA S Phage portal protein gnl|extdb|FAM1079-i1-1.1_002504 797515.HMPREF9103_02438 4.9e-120 437.2 Lactobacillaceae clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR2H@1239,3F5E9@33958,4HBZH@91061,COG0740@1,COG0740@2 NA|NA|NA OU Belongs to the peptidase S14 family gnl|extdb|FAM1079-i1-1.1_002505 1071400.LBUCD034_1581 4.7e-219 766.9 Lactobacillaceae Bacteria 1UACS@1239,3FB8A@33958,4HEAS@91061,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family gnl|extdb|FAM1079-i1-1.1_002507 1423743.JCM14108_2642 2.8e-63 247.7 Lactobacillaceae Bacteria 1VJW9@1239,2E799@1,331SU@2,3F6F8@33958,4HPEE@91061 NA|NA|NA S Phage head-tail joining protein gnl|extdb|FAM1079-i1-1.1_002509 797515.HMPREF9103_02443 2e-67 261.5 Lactobacillaceae Bacteria 1W13M@1239,2FK0I@1,34BNT@2,3F73N@33958,4HYMN@91061 NA|NA|NA S Protein of unknown function (DUF806) gnl|extdb|FAM1079-i1-1.1_002510 1071400.LBUCD034_1577 6.1e-109 400.2 Lactobacillaceae Bacteria 1VXXI@1239,2F78C@1,33ZPM@2,3F5N9@33958,4HWZC@91061 NA|NA|NA S Phage tail tube protein gnl|extdb|FAM1079-i1-1.1_002511 1114972.AUAW01000027_gene720 1.3e-08 64.3 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_002496 797515.HMPREF9103_02490 1.6e-54 218.4 Lactobacillaceae Bacteria 1VA3C@1239,2DJ23@1,32UC6@2,3F7VB@33958,4HPYG@91061 NA|NA|NA S VRR_NUC gnl|extdb|FAM1079-i1-1.1_002506 1423743.JCM14108_2643 7.9e-39 166.0 Lactobacillaceae Bacteria 1VKP6@1239,2EQC3@1,33HY7@2,3F6YI@33958,4HRKR@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002508 797515.HMPREF9103_02442 1.4e-68 265.4 Lactobacillaceae Bacteria 1W3NN@1239,2FCMI@1,2ZDBB@2,3FBBS@33958,4I04D@91061 NA|NA|NA S Bacteriophage HK97-gp10, putative tail-component gnl|extdb|FAM1079-i1-1.1_002512 797515.HMPREF9103_01515 4.4e-147 527.3 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1TX3R@1239,3F45W@33958,4HC85@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins gnl|extdb|FAM1079-i1-1.1_002514 797515.HMPREF9103_01518 0.0 1160.2 Lactobacillaceae 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein gnl|extdb|FAM1079-i1-1.1_002515 1154757.Q5C_00865 7e-35 153.3 Leuconostocaceae ko:K10947 ko00000,ko03000 Bacteria 1VAGB@1239,4AXVY@81850,4HKBS@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family gnl|extdb|FAM1079-i1-1.1_002516 797515.HMPREF9103_01520 1.8e-60 238.4 Lactobacillaceae ORF00048 Bacteria 1V9IF@1239,3FCFG@33958,4HKB8@91061,COG4858@1,COG4858@2 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002517 797515.HMPREF9103_01520 1.1e-66 259.2 Lactobacillaceae ORF00048 Bacteria 1V9IF@1239,3FCFG@33958,4HKB8@91061,COG4858@1,COG4858@2 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002518 797515.HMPREF9103_01521 1.2e-126 459.1 Lactobacillaceae kdgR Bacteria 1V6RZ@1239,3FBFK@33958,4HIPJ@91061,COG1802@1,COG1802@2 NA|NA|NA K FCD domain gnl|extdb|FAM1079-i1-1.1_002519 797515.HMPREF9103_01522 0.0 1099.3 Lactobacillaceae mtlD 1.1.1.17,1.1.1.57 ko:K00009,ko:K00040 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00061 R02454,R02703 RC00085 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ97@1239,3F3XU@33958,4HBQ9@91061,COG0246@1,COG0246@2 NA|NA|NA G Mannitol dehydrogenase C-terminal domain gnl|extdb|FAM1079-i1-1.1_002520 797515.HMPREF9103_01523 2.5e-280 970.7 Lactobacillaceae uxaC 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRI0@1239,3F4QN@33958,4HCGI@91061,COG1904@1,COG1904@2 NA|NA|NA G glucuronate isomerase gnl|extdb|FAM1079-i1-1.1_002521 797515.HMPREF9103_01524 3.2e-169 600.9 Lactobacillaceae yqhA Bacteria 1V3WP@1239,3F5RU@33958,4HHIH@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase gnl|extdb|FAM1079-i1-1.1_002522 797515.HMPREF9103_01525 7.7e-188 662.9 Lactobacillaceae Bacteria 1TPCX@1239,3F5NG@33958,4HUAD@91061,COG1052@1,COG1052@2 NA|NA|NA C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_002523 797515.HMPREF9103_01526 2.2e-298 1030.8 Lactobacillaceae gntK 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family gnl|extdb|FAM1079-i1-1.1_002524 797515.HMPREF9103_01527 1.3e-210 738.8 Bacilli Bacteria 1V0U5@1239,4IRCW@91061,COG4908@1,COG4908@2 NA|NA|NA S protein containing a NRPS condensation (Elongation) domain gnl|extdb|FAM1079-i1-1.1_002525 1231336.L248_1037 1.7e-131 476.5 Lactobacillaceae Bacteria 1TS4Q@1239,3F9RD@33958,4IHF0@91061,COG5434@1,COG5434@2 NA|NA|NA M Glycosyl hydrolases family 28 gnl|extdb|FAM1079-i1-1.1_002527 1121333.JMLH01000011_gene690 1e-127 463.4 Firmicutes 3.2.1.180 ko:K18581 R10867 RC00049,RC02427 ko00000,ko01000 GH88 Bacteria 1UIQN@1239,COG1331@1,COG1331@2 NA|NA|NA O Glycosyl Hydrolase Family 88 gnl|extdb|FAM1079-i1-1.1_002528 1423734.JCM14202_535 3e-92 345.1 Lactobacillaceae Z012_03480 Bacteria 1UQ8F@1239,2DBRG@1,2ZAKM@2,3F6PP@33958,4HHHY@91061 NA|NA|NA S Psort location Cytoplasmic, score gnl|extdb|FAM1079-i1-1.1_002529 511437.Lbuc_0078 7.2e-85 320.5 Lactobacillaceae Bacteria 1TRMW@1239,3FBJX@33958,4HTRE@91061,COG1414@1,COG1414@2 NA|NA|NA K Bacterial transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002531 1136177.KCA1_2945 9.9e-152 542.7 Lactobacillaceae kduI GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008697,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016853,GO:0016860,GO:0016861,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042802,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0046872,GO:0071704,GO:0072329,GO:1901575 5.3.1.17 ko:K01815 ko00040,map00040 R04383 RC00541 ko00000,ko00001,ko01000 Bacteria 1TP4X@1239,3F4U4@33958,4HBJH@91061,COG3717@1,COG3717@2 NA|NA|NA G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate gnl|extdb|FAM1079-i1-1.1_002532 511437.Lbuc_0079 9.6e-136 489.6 Lactobacillaceae Bacteria 1TPZ8@1239,3F4N6@33958,4HAMW@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) gnl|extdb|FAM1079-i1-1.1_002513 797515.HMPREF9103_01517 3.2e-264 917.1 Lactobacillaceae ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM1079-i1-1.1_002526 314315.LCA_1786 5.1e-162 577.4 Lactobacillaceae Bacteria 1V3NJ@1239,3F4KD@33958,4HTUC@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator gnl|extdb|FAM1079-i1-1.1_002533 1336243.JAEA01000003_gene2385 8.8e-15 85.9 Methylobacteriaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1JT7Q@119045,1QTTK@1224,2TQSF@28211,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system gnl|extdb|FAM1079-i1-1.1_002534 1423806.JCM15457_1824 7e-111 407.5 Lactobacillaceae ykrV3 2.6.1.83 ko:K08969,ko:K10206 ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230 M00034,M00527 R07396,R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQD6@1239,3F4TW@33958,4HAHQ@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase gnl|extdb|FAM1079-i1-1.1_002535 203123.OEOE_1057 3.9e-46 191.0 Leuconostocaceae yebR 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 1V6GQ@1239,4AXSQ@81850,4HH7X@91061,COG1956@1,COG1956@2 NA|NA|NA T GAF domain gnl|extdb|FAM1079-i1-1.1_002536 797515.HMPREF9103_00722 8.3e-215 752.7 Lactobacillaceae gldA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0042802,GO:0047545,GO:0055114 1.1.1.1,1.1.1.6 ko:K00001,ko:K00005,ko:K08317 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R01034,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10715,R10717 RC00029,RC00050,RC00087,RC00088,RC00099,RC00116,RC00117,RC00649,RC00670,RC01734,RC02273 ko00000,ko00001,ko01000 iJN678.gldA Bacteria 1TQFU@1239,3F4E4@33958,4HC8K@91061,COG0371@1,COG0371@2 NA|NA|NA C dehydrogenase gnl|extdb|FAM1079-i1-1.1_002537 1423743.JCM14108_2994 4e-234 817.4 Lactobacillaceae ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein gnl|extdb|FAM1079-i1-1.1_002538 797515.HMPREF9103_00719 7.9e-134 483.0 Lactobacillaceae puuD ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F4PK@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S peptidase C26 gnl|extdb|FAM1079-i1-1.1_002539 797515.HMPREF9103_00718 9.3e-74 282.7 Lactobacillaceae Bacteria 1VCK0@1239,3F799@33958,4I1W9@91061,COG0716@1,COG0716@2 NA|NA|NA C FMN binding gnl|extdb|FAM1079-i1-1.1_002540 797515.HMPREF9103_00717 0.0 1251.5 Lactobacillaceae copB 3.6.3.4 ko:K01533 R00086 RC00002 ko00000,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase gnl|extdb|FAM1079-i1-1.1_002541 797515.HMPREF9103_00715 1.2e-109 402.5 Lactobacillaceae Bacteria 1VB1Q@1239,2DS3U@1,32USA@2,3F6QK@33958,4IFMV@91061 NA|NA|NA S Golgi phosphoprotein 3 (GPP34) gnl|extdb|FAM1079-i1-1.1_002542 797515.HMPREF9103_00714 6.9e-203 713.0 Lactobacillaceae 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F49I@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Bacterial lipoate protein ligase C-terminus gnl|extdb|FAM1079-i1-1.1_002543 797515.HMPREF9103_00713 3.7e-170 604.0 Lactobacillaceae Bacteria 1TQB7@1239,3FBIY@33958,4HAQT@91061,COG0846@1,COG0846@2 NA|NA|NA K COG COG0846 NAD-dependent protein deacetylases, SIR2 family gnl|extdb|FAM1079-i1-1.1_002544 797515.HMPREF9103_00712 4e-147 527.3 Lactobacillaceae ymdB Bacteria 1TQSZ@1239,3FBC5@33958,4HCXD@91061,COG2110@1,COG2110@2 NA|NA|NA S Macro domain gnl|extdb|FAM1079-i1-1.1_002545 797515.HMPREF9103_00711 3.4e-55 220.7 Bacilli gcdH Bacteria 1VAMB@1239,4HKV0@91061,COG0509@1,COG0509@2 NA|NA|NA E glycine cleavage gnl|extdb|FAM1079-i1-1.1_002546 525318.HMPREF0497_1816 3.5e-198 697.6 Lactobacillaceae baiH Bacteria 1TPM6@1239,3F9N0@33958,4HAS5@91061,COG1902@1,COG1902@2 NA|NA|NA C Oxidoreductase, FAD FMN-binding protein gnl|extdb|FAM1079-i1-1.1_002547 797515.HMPREF9103_00707 0.0 1442.6 Lactobacillaceae sbcC ko:K03546 ko00000,ko03400 Bacteria 1TPCS@1239,3F3TE@33958,4H9Q3@91061,COG0419@1,COG0419@2 NA|NA|NA L Putative exonuclease SbcCD, C subunit gnl|extdb|FAM1079-i1-1.1_002548 797515.HMPREF9103_00706 1.2e-216 758.8 Lactobacillaceae sbcD ko:K03547 ko00000,ko03400 Bacteria 1TQY6@1239,3F4A9@33958,4HAKB@91061,COG0420@1,COG0420@2 NA|NA|NA L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity gnl|extdb|FAM1079-i1-1.1_002549 797515.HMPREF9103_00705 1.4e-163 582.4 Lactobacillaceae Bacteria 1VA42@1239,3FBMH@33958,4IR5W@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain gnl|extdb|FAM1079-i1-1.1_002550 797515.HMPREF9103_00704 6.7e-201 706.4 Lactobacillaceae ysaA Bacteria 1V4NX@1239,3FBFR@33958,4IPYM@91061,COG4767@1,COG4767@2 NA|NA|NA V RDD family gnl|extdb|FAM1079-i1-1.1_002551 797515.HMPREF9103_00702 1.3e-190 672.2 Lactobacillaceae 4.4.1.15,4.4.1.25 ko:K05396,ko:K17950 ko00270,map00270 R01874,R07634 RC00382,RC01784 ko00000,ko00001,ko01000 Bacteria 1UDCW@1239,3F5YR@33958,4IF8C@91061,COG2515@1,COG2515@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme gnl|extdb|FAM1079-i1-1.1_002552 904306.HMPREF9192_0883 2.7e-35 155.2 Bacilli Bacteria 1TR6E@1239,4HCAZ@91061,COG3547@1,COG3547@2 NA|NA|NA L transposase IS116 IS110 IS902 family gnl|extdb|FAM1079-i1-1.1_002553 797515.HMPREF9103_02322 4.3e-74 283.9 Lactobacillaceae Bacteria 1TUVU@1239,3F89H@33958,4IE51@91061,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 gnl|extdb|FAM1079-i1-1.1_002554 1423780.LOT_1561 1.5e-87 329.3 Lactobacillaceae ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F6U5@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S Peptidase C26 gnl|extdb|FAM1079-i1-1.1_002556 1423780.LOT_1448 5.9e-267 926.8 Lactobacillaceae Bacteria 1TZSZ@1239,2DB7A@1,2Z7KK@2,3F5CP@33958,4HFM6@91061 NA|NA|NA S Glycosyl hydrolase family 115 gnl|extdb|FAM1079-i1-1.1_002558 324057.Pjdr2_5534 1.5e-104 387.5 Paenibacillaceae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1UIPP@1239,2775K@186822,4ISP9@91061,COG3693@1,COG3693@2,COG5184@1,COG5184@2,COG5434@1,COG5434@2 NA|NA|NA G PFAM Glycoside hydrolase, family 10 gnl|extdb|FAM1079-i1-1.1_002559 1423780.LOT_1453 3.2e-81 308.5 Lactobacillaceae Bacteria 1UX6U@1239,3F6PR@33958,4IFMF@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein gnl|extdb|FAM1079-i1-1.1_002561 797515.HMPREF9103_02270 5.2e-82 310.5 Lactobacillaceae Bacteria 1VMIT@1239,29NUX@1,33IN1@2,3F7TC@33958,4HRE8@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002562 797515.HMPREF9103_02271 2.3e-31 141.0 Lactobacillaceae yozG ko:K07727 ko00000,ko03000 Bacteria 1VESP@1239,3F802@33958,4HPRB@91061,COG3655@1,COG3655@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002563 1071400.LBUCD034_0299 6.7e-37 159.5 Lactobacillaceae chpR GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044877,GO:0046983,GO:0051259,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:0097351,GO:1901363 ko:K07172,ko:K18829 ko00000,ko02048 Bacteria 1VPRD@1239,3F8B3@33958,4HRKY@91061,COG2336@1,COG2336@2 NA|NA|NA T PFAM SpoVT AbrB gnl|extdb|FAM1079-i1-1.1_002564 797515.HMPREF9103_02272 1.4e-62 245.4 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1U642@1239,3F6ZN@33958,4IFTM@91061,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system gnl|extdb|FAM1079-i1-1.1_002565 525318.HMPREF0497_2152 0.0 1089.7 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter gnl|extdb|FAM1079-i1-1.1_002566 797515.HMPREF9103_02276 1.7e-154 552.0 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TSB5@1239,3F5CF@33958,4HDM2@91061,COG0619@1,COG0619@2 NA|NA|NA P ABC-type cobalt transport system permease component CbiQ and related transporters gnl|extdb|FAM1079-i1-1.1_002567 797515.HMPREF9103_02277 2.3e-311 1074.3 Lactobacillaceae ykoD_2 ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1UI2B@1239,3FBVX@33958,4ISBR@91061,COG3845@1,COG3845@2 NA|NA|NA S AAA domain, putative AbiEii toxin, Type IV TA system gnl|extdb|FAM1079-i1-1.1_002568 405566.lhv_1956 2.7e-118 431.4 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V2DR@1239,3F4W4@33958,4HFXY@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component gnl|extdb|FAM1079-i1-1.1_002569 797515.HMPREF9103_02279 1e-177 629.4 Lactobacillaceae Bacteria 1W217@1239,3F5DS@33958,4ITF7@91061,COG5066@1,COG5066@2 NA|NA|NA U FFAT motif binding gnl|extdb|FAM1079-i1-1.1_002570 1033837.WANG_1509 1.7e-67 261.9 Lactobacillaceae eutP ko:K04029 ko00000 Bacteria 1VAYC@1239,3F7NM@33958,4HJN3@91061,COG4917@1,COG4917@2 NA|NA|NA E Ethanolamine utilisation - propanediol utilisation gnl|extdb|FAM1079-i1-1.1_002555 1423780.LOT_1450 2.5e-43 181.4 Lactobacillaceae Bacteria 1U6EE@1239,29PCD@1,30AAM@2,3F7QF@33958,4IG66@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002557 1138822.PL11_07755 2e-225 788.5 Lactobacillaceae ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 1U037@1239,3F4MV@33958,4HBZK@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_002560 797515.HMPREF9103_02329 5.8e-189 666.8 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity gnl|extdb|FAM1079-i1-1.1_002571 797515.HMPREF9103_00944 3.5e-149 534.3 Lactobacillaceae manN ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TQA3@1239,3F3KR@33958,4HA3K@91061,COG3716@1,COG3716@2 NA|NA|NA G system, mannose fructose sorbose family IID component gnl|extdb|FAM1079-i1-1.1_002572 797515.HMPREF9103_00943 5.3e-139 500.4 Lactobacillaceae manM ko:K02795,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TPKK@1239,3F3V5@33958,4H9QI@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system gnl|extdb|FAM1079-i1-1.1_002573 797515.HMPREF9103_00942 8e-88 329.7 Lactobacillaceae pts10B 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 Bacteria 1V3X7@1239,3FC7Q@33958,4HH17@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component gnl|extdb|FAM1079-i1-1.1_002575 797515.HMPREF9103_00940 1.4e-113 415.6 Lactobacillaceae gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V7U6@1239,3F658@33958,4HJ9I@91061,COG0546@1,COG0546@2 NA|NA|NA S HAD hydrolase, family IA, variant gnl|extdb|FAM1079-i1-1.1_002577 797515.HMPREF9103_00938 1.9e-158 565.1 Lactobacillaceae thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 1TRWS@1239,3F44T@33958,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate gnl|extdb|FAM1079-i1-1.1_002578 797515.HMPREF9103_00937 2.3e-86 324.7 Lactobacillaceae ydcK ko:K03095 ko00000 Bacteria 1V6NU@1239,3F703@33958,4HIHY@91061,COG3091@1,COG3091@2 NA|NA|NA S Belongs to the SprT family gnl|extdb|FAM1079-i1-1.1_002579 797515.HMPREF9103_00936 0.0 1405.2 Lactobacillaceae yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K06959 ko00000 Bacteria 1TPFE@1239,3F415@33958,4HAGY@91061,COG2183@1,COG2183@2 NA|NA|NA K Tex-like protein N-terminal domain protein gnl|extdb|FAM1079-i1-1.1_002580 797515.HMPREF9103_00934 5.2e-72 276.9 Lactobacillaceae ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1VFU9@1239,2E7AN@1,331U3@2,3F69A@33958,4HP1H@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002581 797515.HMPREF9103_00933 0.0 1607.4 Lactobacillaceae pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase gnl|extdb|FAM1079-i1-1.1_002582 797515.HMPREF9103_00932 1.3e-151 542.3 Lactobacillaceae nadE GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 1TQ38@1239,3F43Z@33958,4HA2R@91061,COG0171@1,COG0171@2 NA|NA|NA F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source gnl|extdb|FAM1079-i1-1.1_002583 797515.HMPREF9103_00931 1.2e-282 978.4 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP gnl|extdb|FAM1079-i1-1.1_002584 797515.HMPREF9103_00930 1.2e-137 495.7 Lactobacillaceae tagA 2.4.1.187 ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 GT26 Bacteria 1V3QV@1239,3F4WB@33958,4HH6B@91061,COG1922@1,COG1922@2 NA|NA|NA F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid gnl|extdb|FAM1079-i1-1.1_002585 797515.HMPREF9103_00929 2.9e-125 454.5 Lactobacillaceae gntR1 ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1UYBW@1239,3F4D0@33958,4HDDG@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein gnl|extdb|FAM1079-i1-1.1_002591 1423780.LOT_0003 5.8e-248 863.2 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter gnl|extdb|FAM1079-i1-1.1_002592 797515.HMPREF9103_02462 4e-47 193.7 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1UPS9@1239,2BT36@1,32N7P@2,3F886@33958,4IV9X@91061 NA|NA|NA S PTS system, Lactose/Cellobiose specific IIA subunit gnl|extdb|FAM1079-i1-1.1_002593 797515.HMPREF9103_02461 1.5e-52 211.8 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1U66M@1239,2AP2T@1,31E49@2,3F76X@33958,4IFWW@91061 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit gnl|extdb|FAM1079-i1-1.1_002574 797515.HMPREF9103_00941 1.1e-66 259.2 Lactobacillaceae 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1VB4C@1239,3FBI3@33958,4I150@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component gnl|extdb|FAM1079-i1-1.1_002587 797515.HMPREF9103_00927 2.8e-135 488.0 Lactobacillaceae proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1E@1239,3F4SE@33958,4H9RV@91061,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline gnl|extdb|FAM1079-i1-1.1_002595 797515.HMPREF9103_02623 7.2e-222 776.2 Lactobacillaceae rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1TP0X@1239,3F3NZ@33958,4HBKY@91061,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily gnl|extdb|FAM1079-i1-1.1_002596 797515.HMPREF9103_02622 2.3e-204 718.0 Lactobacillaceae yurR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 1.4.5.1 ko:K00285 ko00360,map00360 R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 Bacteria 1TQTF@1239,3F410@33958,4HA0F@91061,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase gnl|extdb|FAM1079-i1-1.1_002597 797515.HMPREF9103_02621 7.2e-65 253.1 Lactobacillaceae rnhA 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1VH2B@1239,3F7JC@33958,4HIY9@91061,COG0328@1,COG0328@2 NA|NA|NA L Ribonuclease HI gnl|extdb|FAM1079-i1-1.1_002598 797515.HMPREF9103_02620 1.6e-67 261.9 Lactobacillaceae esbA Bacteria 1W31C@1239,2BZWG@1,2ZPAS@2,3F6SQ@33958,4I09H@91061 NA|NA|NA S Family of unknown function (DUF5322) gnl|extdb|FAM1079-i1-1.1_002599 797515.HMPREF9103_02619 0.0 1101.3 Lactobacillaceae fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family gnl|extdb|FAM1079-i1-1.1_002600 797515.HMPREF9103_02618 4e-72 277.3 Lactobacillaceae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1VA9R@1239,3F66R@33958,4HIR4@91061,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins gnl|extdb|FAM1079-i1-1.1_002601 797515.HMPREF9103_02617 4.6e-171 607.1 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TPCM@1239,3F3P6@33958,4HBG2@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil gnl|extdb|FAM1079-i1-1.1_002602 797515.HMPREF9103_02616 8.9e-90 336.3 Lactobacillaceae pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 1V3GV@1239,3F4SR@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant gnl|extdb|FAM1079-i1-1.1_002603 797515.HMPREF9103_02615 3.9e-209 733.8 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1VTN5@1239,3FC4C@33958,4HT8S@91061,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family gnl|extdb|FAM1079-i1-1.1_002604 797515.HMPREF9103_02614 0.0 1659.4 Lactobacillaceae carB 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase gnl|extdb|FAM1079-i1-1.1_002605 797515.HMPREF9103_02613 0.0 1097.4 Lactobacillaceae FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,3F3PS@33958,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K Fibronectin-binding protein gnl|extdb|FAM1079-i1-1.1_002606 797515.HMPREF9103_02612 7.6e-65 253.1 Lactobacillaceae Bacteria 1VCKC@1239,3F7BA@33958,4HPTV@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002607 797515.HMPREF9103_02611 2.7e-160 571.2 Lactobacillaceae degV Bacteria 1TRM7@1239,3F40W@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family gnl|extdb|FAM1079-i1-1.1_002608 797515.HMPREF9103_02610 1.9e-87 328.6 Lactobacillaceae folT 2.7.13.3 ko:K02478,ko:K07704 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1VB87@1239,3FBSH@33958,4ISET@91061,COG3275@1,COG3275@2 NA|NA|NA T ECF transporter, substrate-specific component gnl|extdb|FAM1079-i1-1.1_002609 797515.HMPREF9103_02609 4.2e-56 223.8 Lactobacillaceae folB 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA0I@1239,3F7N6@33958,4HKKK@91061,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin gnl|extdb|FAM1079-i1-1.1_002610 797515.HMPREF9103_02608 9.8e-205 719.2 Lactobacillaceae folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.5.1.15,2.7.6.3,3.5.4.16,4.1.2.25 ko:K00796,ko:K00950,ko:K01495,ko:K13940,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3609c Bacteria 1TRNM@1239,3F4A0@33958,4HAXS@91061,COG0302@1,COG0302@2,COG0801@1,COG0801@2 NA|NA|NA F GTP cyclohydrolase 1 gnl|extdb|FAM1079-i1-1.1_002611 797515.HMPREF9103_02607 5e-246 856.7 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F3ZR@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family gnl|extdb|FAM1079-i1-1.1_002613 797515.HMPREF9103_02605 9.7e-89 332.8 Lactobacillaceae 3.6.1.55,3.6.1.67 ko:K03574,ko:K19965 ko00790,map00790 M00126 R04638 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1VFNI@1239,3F4CG@33958,4HQPJ@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain gnl|extdb|FAM1079-i1-1.1_002614 797515.HMPREF9103_02604 5.2e-150 537.0 Lactobacillaceae hutG 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6B3@1239,3F6V6@33958,4HQ4E@91061,COG3741@1,COG3741@2 NA|NA|NA E N-formylglutamate amidohydrolase gnl|extdb|FAM1079-i1-1.1_002615 797515.HMPREF9103_02603 2.2e-75 288.1 Lactobacillaceae ypeA 2.3.1.1 ko:K03826,ko:K22477 ko00220,ko01210,ko01230,map00220,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 Bacteria 1V5WU@1239,3F7E9@33958,4IQ5F@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain gnl|extdb|FAM1079-i1-1.1_002612 797515.HMPREF9103_02606 3.5e-157 560.8 Lactobacillaceae folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796,ko:K18824,ko:K18974 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPKT@1239,3F4SS@33958,4H9SY@91061,COG0294@1,COG0294@2 NA|NA|NA H dihydropteroate synthase gnl|extdb|FAM1079-i1-1.1_002616 797515.HMPREF9103_01495 8e-174 616.3 Lactobacillaceae Bacteria 1TQ0M@1239,3F4EJ@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase gnl|extdb|FAM1079-i1-1.1_002617 797515.HMPREF9103_01496 3.1e-59 234.2 Lactobacillaceae yqkB Bacteria 1VK6M@1239,3F7JD@33958,4HRFS@91061,COG4918@1,COG4918@2 NA|NA|NA S Belongs to the HesB IscA family gnl|extdb|FAM1079-i1-1.1_002618 797515.HMPREF9103_01497 1e-251 875.5 Lactobacillaceae ciaH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TS5K@1239,3F5EI@33958,4H9Y1@91061,COG5002@1,COG5002@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein gnl|extdb|FAM1079-i1-1.1_002619 797515.HMPREF9103_01498 1.8e-104 385.2 Lactobacillaceae yiiE Bacteria 1VAQZ@1239,3F6Q5@33958,4HJFH@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) gnl|extdb|FAM1079-i1-1.1_002620 525318.HMPREF0497_1499 3.1e-214 751.1 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid gnl|extdb|FAM1079-i1-1.1_002622 797515.HMPREF9103_01502 2.6e-214 751.1 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002623 797515.HMPREF9103_01504 9.6e-209 732.6 Lactobacillaceae uhpT Bacteria 1TQZ7@1239,3F54C@33958,4HERG@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002624 797515.HMPREF9103_01505 0.0 1507.3 Lactobacillaceae rafA GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009987,GO:0010033,GO:0015925,GO:0016043,GO:0016052,GO:0016787,GO:0016798,GO:0022607,GO:0042221,GO:0043933,GO:0044085,GO:0044238,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901545,GO:1901575,GO:1901700 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase gnl|extdb|FAM1079-i1-1.1_002625 797515.HMPREF9103_01506 1.3e-190 672.2 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator gnl|extdb|FAM1079-i1-1.1_002626 797515.HMPREF9103_01507 1.4e-74 285.4 Lactobacillaceae Bacteria 1VBJ0@1239,3F664@33958,4HNBY@91061,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein gnl|extdb|FAM1079-i1-1.1_002627 797515.HMPREF9103_01508 1.2e-123 449.1 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1V5YV@1239,3F4G0@33958,4HH6T@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent gnl|extdb|FAM1079-i1-1.1_002628 797515.HMPREF9103_01509 4.2e-200 703.7 Lactobacillaceae XK27_00915 Bacteria 1TRBN@1239,3F4KZ@33958,4HBYT@91061,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase gnl|extdb|FAM1079-i1-1.1_002629 797515.HMPREF9103_01511 3e-87 327.8 Lactobacillaceae iap ko:K19224,ko:K21471 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 1V9ZW@1239,3F6DD@33958,4HH84@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family gnl|extdb|FAM1079-i1-1.1_002630 797515.HMPREF9103_01512 1.3e-165 589.0 Lactobacillaceae XK27_00880 3.5.1.28 ko:K01447,ko:K07273 R04112 RC00064,RC00141 ko00000,ko01000 Bacteria 1V2YH@1239,3F4GR@33958,4HKBF@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 gnl|extdb|FAM1079-i1-1.1_002631 797515.HMPREF9103_01513 0.0 1686.0 Lactobacillaceae Bacteria 1TRR1@1239,3F49G@33958,4HBW6@91061,COG4485@1,COG4485@2 NA|NA|NA S membrane gnl|extdb|FAM1079-i1-1.1_002632 525318.HMPREF0497_1506 2.4e-156 558.1 Lactobacillaceae gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHN4@1239,3F4X7@33958,4IS44@91061,COG1023@1,COG1023@2 NA|NA|NA G Dehydrogenase gnl|extdb|FAM1079-i1-1.1_002634 797515.HMPREF9103_03064 2.7e-108 397.9 Lactobacillaceae ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,3F3TI@33958,4H9V0@91061,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gnl|extdb|FAM1079-i1-1.1_002635 525318.HMPREF0497_1920 4.5e-168 597.4 Lactobacillaceae 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPUV@1239,3F5EW@33958,4HGH7@91061,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily gnl|extdb|FAM1079-i1-1.1_002636 797515.HMPREF9103_03068 3.8e-147 527.3 Lactobacillaceae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,3F4GK@33958,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III gnl|extdb|FAM1079-i1-1.1_002637 797515.HMPREF9103_03069 1.7e-112 412.1 Lactobacillaceae Bacteria 1VDDQ@1239,2C9UQ@1,32RPZ@2,3F5X9@33958,4HNJB@91061 NA|NA|NA S Domain of unknown function (DUF4811) gnl|extdb|FAM1079-i1-1.1_002638 797515.HMPREF9103_03070 4.3e-267 926.8 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002639 797515.HMPREF9103_03071 5e-78 297.0 Lactobacillaceae merR ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1VZ9X@1239,3FBR0@33958,4HYI3@91061,COG0789@1,COG0789@2 NA|NA|NA K MerR HTH family regulatory protein gnl|extdb|FAM1079-i1-1.1_002640 797515.HMPREF9103_03072 2.7e-38 164.1 Lactobacillaceae Bacteria 1V64Y@1239,3F812@33958,4HNUM@91061,COG4892@1,COG4892@2 NA|NA|NA S Cytochrome B5 gnl|extdb|FAM1079-i1-1.1_002641 797515.HMPREF9103_03073 3e-207 727.6 Lactobacillaceae cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1TSG4@1239,3F3PA@33958,4HDKI@91061,COG2230@1,COG2230@2 NA|NA|NA M cyclopropane-fatty-acyl-phospholipid synthase gnl|extdb|FAM1079-i1-1.1_002642 1423743.JCM14108_3124 1e-69 270.4 Lactobacillaceae Bacteria 1U5QV@1239,29PC0@1,309UH@2,3F6BY@33958,4IFEY@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002645 797515.HMPREF9103_03046 7.2e-172 609.8 Lactobacillaceae Bacteria 1TRVX@1239,3F48I@33958,4HFSV@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family gnl|extdb|FAM1079-i1-1.1_002646 797515.HMPREF9103_03045 8.7e-131 473.0 Lactobacillaceae aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSPN@1239,3F4TX@33958,4HDMG@91061,COG0710@1,COG0710@2 NA|NA|NA E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate gnl|extdb|FAM1079-i1-1.1_002647 797515.HMPREF9103_03044 2.6e-180 637.9 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3F5ID@33958,4HHVC@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein gnl|extdb|FAM1079-i1-1.1_002648 1122149.BACN01000021_gene554 0.0 1114.0 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TTD3@1239,3F5DN@33958,4HT4K@91061,COG0431@1,COG0431@2,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain gnl|extdb|FAM1079-i1-1.1_002649 797515.HMPREF9103_03041 2.5e-158 564.7 Lactobacillaceae aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0030266,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0052734,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,1.1.1.282,1.3.5.4 ko:K00014,ko:K00244,ko:K05887 ko00020,ko00190,ko00400,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02020,map00020,map00190,map00400,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map01230,map02020 M00009,M00011,M00022,M00150,M00173 R01872,R02164,R02413,R06846,R06847 RC00045,RC00154,RC00206 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS14185,iSFxv_1172.SFxv_1929,iS_1188.S1854 Bacteria 1TQRY@1239,3F4WM@33958,4HD4R@91061,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) gnl|extdb|FAM1079-i1-1.1_002650 60520.HR47_11130 4.6e-169 600.9 Lactobacillaceae ydiM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015291,GO:0015292,GO:0016020,GO:0022804,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1UI3V@1239,3FBSK@33958,4HBYF@91061,COG2271@1,COG2271@2 NA|NA|NA G Transporter gnl|extdb|FAM1079-i1-1.1_002643 797515.HMPREF9103_03074 1.4e-192 678.7 Lactobacillaceae 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gnl|extdb|FAM1079-i1-1.1_002644 797515.HMPREF9103_03047 2.2e-213 748.0 Lactobacillaceae ydiN GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015291,GO:0015292,GO:0016020,GO:0022804,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1UI3V@1239,3F3ZF@33958,4ISEV@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily gnl|extdb|FAM1079-i1-1.1_002652 797515.HMPREF9103_00166 1.7e-176 625.2 Lactobacillaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,3F42Q@33958,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase gnl|extdb|FAM1079-i1-1.1_002653 797515.HMPREF9103_00167 3.5e-304 1050.0 Lactobacillaceae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iLJ478.TM1820 Bacteria 1TPG8@1239,3F3NV@33958,4HA7Q@91061,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP gnl|extdb|FAM1079-i1-1.1_002654 797515.HMPREF9103_00168 1.6e-73 282.0 Lactobacillaceae uspA Bacteria 1VEJR@1239,3F8D9@33958,4HR56@91061,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family gnl|extdb|FAM1079-i1-1.1_002655 797515.HMPREF9103_00169 6.1e-62 243.4 Lactobacillaceae arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1V3JW@1239,3F6GQ@33958,4HH49@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family gnl|extdb|FAM1079-i1-1.1_002656 797515.HMPREF9103_00170 6.5e-151 540.0 Lactobacillaceae Bacteria 1TRAU@1239,3F54J@33958,4H9UY@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 gnl|extdb|FAM1079-i1-1.1_002658 797515.HMPREF9103_00173 3.9e-72 277.3 Lactobacillaceae uspA Bacteria 1VEJR@1239,3F8D9@33958,4HR56@91061,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family gnl|extdb|FAM1079-i1-1.1_002659 314315.LCA_0639 3.4e-28 131.0 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VA8U@1239,3F7JQ@33958,4HKPC@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family gnl|extdb|FAM1079-i1-1.1_002660 1423747.BAMJ01000002_gene160 2.1e-13 82.8 Lactobacillaceae Bacteria 1TTWE@1239,3F7BH@33958,4I33X@91061,COG4709@1,COG4709@2 NA|NA|NA S Protein of unknown function (DUF1700) gnl|extdb|FAM1079-i1-1.1_002664 797515.HMPREF9103_02329 1.3e-35 157.5 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity gnl|extdb|FAM1079-i1-1.1_002665 1071400.LBUCD034_1885 0.0 1403.3 Lactobacillaceae pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR43@1239,3F3UH@33958,4HA20@91061,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase gnl|extdb|FAM1079-i1-1.1_002666 797515.HMPREF9103_03059 2e-92 345.1 Lactobacillaceae cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1U5WV@1239,3F6MR@33958,4IFKD@91061,COG1286@1,COG1286@2 NA|NA|NA S Colicin V production protein gnl|extdb|FAM1079-i1-1.1_002667 797515.HMPREF9103_03060 1.6e-123 448.7 Lactobacillaceae zmp3 Bacteria 1V6X9@1239,3F6QI@33958,4HK8S@91061,COG5549@1,COG5549@2 NA|NA|NA O Zinc-dependent metalloprotease gnl|extdb|FAM1079-i1-1.1_002668 797515.HMPREF9103_03062 4.3e-121 440.7 Lactobacillaceae XK27_12570 5.1.3.9 ko:K01788 ko00520,map00520 R02087 RC00290 ko00000,ko00001,ko01000 Bacteria 1VTI6@1239,3F3YB@33958,4HV5Q@91061,COG3010@1,COG3010@2 NA|NA|NA G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) gnl|extdb|FAM1079-i1-1.1_002671 1400520.LFAB_17190 1.3e-110 406.0 Lactobacillaceae Bacteria 1V10X@1239,3F3Z4@33958,4H9UD@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor gnl|extdb|FAM1079-i1-1.1_002672 1123298.KB904062_gene946 5.7e-44 184.9 Bacilli Bacteria 1V6C2@1239,4HTFX@91061,COG3039@1,COG3039@2 NA|NA|NA L the current gene model (or a revised gene model) may contain a frame shift gnl|extdb|FAM1079-i1-1.1_002674 888064.HMPREF9088_1402 1.9e-07 62.4 Enterococcaceae ko:K02171 ko01501,map01501 M00627 ko00000,ko00001,ko00002,ko01504,ko03000 Bacteria 1U26M@1239,4B3SE@81852,4IBQD@91061,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor gnl|extdb|FAM1079-i1-1.1_002677 1074451.CRL705_1644 8.2e-38 162.5 Lactobacillaceae ko:K07483 ko00000 Bacteria 1VIEV@1239,3F6X7@33958,4HJSC@91061,COG2963@1,COG2963@2 NA|NA|NA L Transposase and inactivated derivatives gnl|extdb|FAM1079-i1-1.1_002678 1423734.JCM14202_2816 7.3e-155 553.1 Lactobacillaceae Bacteria 1TU21@1239,3F46G@33958,4HDK4@91061,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_002680 1423743.JCM14108_3009 1.2e-118 432.6 Lactobacillaceae Bacteria 1TPQG@1239,3F4FB@33958,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator gnl|extdb|FAM1079-i1-1.1_002682 1423743.JCM14108_3007 1.5e-149 535.4 Lactobacillaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,3F42N@33958,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins gnl|extdb|FAM1079-i1-1.1_002683 1423743.JCM14108_3006 1.3e-72 278.9 Lactobacillaceae spx4 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1TTEA@1239,3F6ZW@33958,4I3R5@91061,COG1393@1,COG1393@2 NA|NA|NA P ArsC family gnl|extdb|FAM1079-i1-1.1_002686 1423743.JCM14108_2827 0.0 1492.2 Lactobacillaceae gshF 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG0151@1,COG0151@2,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family gnl|extdb|FAM1079-i1-1.1_002687 1449343.JQLQ01000002_gene2372 6.7e-35 153.7 Carnobacteriaceae Bacteria 1VCR8@1239,27GGU@186828,4HKP0@91061,COG5341@1,COG5341@2 NA|NA|NA S NusG domain II gnl|extdb|FAM1079-i1-1.1_002689 1114972.AUAW01000027_gene732 5e-50 203.4 Lactobacillaceae Bacteria 1U9EJ@1239,29R7X@1,30C99@2,3F895@33958,4IJHG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002693 511437.Lbuc_0028 2.8e-87 328.6 Lactobacillaceae tnp2PF3 Bacteria 1VXWA@1239,3F6KZ@33958,4HXG3@91061,COG3293@1,COG3293@2 NA|NA|NA L manually curated gnl|extdb|FAM1079-i1-1.1_002695 1045004.OKIT_0519 7.3e-43 179.5 Bacilli relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family gnl|extdb|FAM1079-i1-1.1_002696 1423780.LOT_2226 3.1e-22 110.2 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A gnl|extdb|FAM1079-i1-1.1_002681 1423743.JCM14108_3008 4.5e-155 553.9 Lactobacillaceae baeS 2.7.13.3 ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3FBSR@33958,4IS6U@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase gnl|extdb|FAM1079-i1-1.1_002694 1423743.JCM14108_3252 1.2e-37 162.2 Lactobacillaceae Bacteria 1VQDB@1239,2EHZR@1,33BR8@2,3F5IT@33958,4HRJT@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002698 797515.HMPREF9103_01664 5.1e-198 696.8 Lactobacillaceae pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3J@1239,3F3RC@33958,4HBHB@91061,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller gnl|extdb|FAM1079-i1-1.1_002700 797515.HMPREF9103_01662 2.8e-84 317.8 Lactobacillaceae perR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K03711,ko:K09825 ko00000,ko03000 Bacteria 1V400@1239,3F67J@33958,4HHF8@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family gnl|extdb|FAM1079-i1-1.1_002701 797515.HMPREF9103_01661 9.8e-180 636.0 Lactobacillaceae 3.2.1.96,3.5.1.28 ko:K01227,ko:K01447,ko:K13731 ko00511,ko05100,map00511,map05100 R04112 RC00064,RC00141 ko00000,ko00001,ko01000 Bacteria 1V3MY@1239,3F4BU@33958,4HBWG@91061,COG5632@1,COG5632@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase gnl|extdb|FAM1079-i1-1.1_002703 797515.HMPREF9103_01658 1.7e-229 801.6 Lactobacillaceae proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130 Bacteria 1TQ9V@1239,3F3W7@33958,4HB7B@91061,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate gnl|extdb|FAM1079-i1-1.1_002704 797515.HMPREF9103_01657 3.3e-134 484.6 Lactobacillaceae Bacteria 1U6A2@1239,29PC0@1,30A75@2,3F7EU@33958,4IG1A@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002705 797515.HMPREF9103_01656 5e-165 587.0 Lactobacillaceae 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F5CQ@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain gnl|extdb|FAM1079-i1-1.1_002706 797515.HMPREF9103_01655 2.3e-136 491.5 Lactobacillaceae Bacteria 1UIIR@1239,3F5MJ@33958,4ISJH@91061,COG2227@1,COG2227@2 NA|NA|NA H Protein of unknown function (DUF1698) gnl|extdb|FAM1079-i1-1.1_002707 797515.HMPREF9103_01654 1.1e-76 292.7 Lactobacillaceae Bacteria 1U7NF@1239,2AHHP@1,317V7@2,3F9Y5@33958,4IHJQ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002708 797515.HMPREF9103_01653 2.2e-97 362.1 Lactobacillaceae yibF Bacteria 1TSWX@1239,3F3S6@33958,4HBKX@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name gnl|extdb|FAM1079-i1-1.1_002709 797515.HMPREF9103_01652 1.5e-195 688.7 Lactobacillaceae yibE Bacteria 1TPEV@1239,3F3M9@33958,4HCP3@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name gnl|extdb|FAM1079-i1-1.1_002710 797515.HMPREF9103_01651 3.8e-193 680.6 Lactobacillaceae fic Bacteria 1TQMC@1239,3F45Y@33958,4HBA4@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family gnl|extdb|FAM1079-i1-1.1_002711 797515.HMPREF9103_00768 1.5e-228 798.5 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family gnl|extdb|FAM1079-i1-1.1_002712 797515.HMPREF9103_00767 1.3e-75 288.9 Lactobacillaceae tlpA2 ko:K07491 ko00000 Bacteria 1VAIQ@1239,3F68H@33958,4HI29@91061,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like gnl|extdb|FAM1079-i1-1.1_002713 797515.HMPREF9103_01650 2e-125 455.3 Lactobacillaceae Bacteria 1U5DH@1239,2DKJ3@1,309NE@2,3F5MT@33958,4IF4V@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002714 525318.HMPREF0497_0052 1e-29 137.1 Lactobacillaceae Bacteria 1U5KN@1239,29NU6@1,309SA@2,3F65P@33958,4IFBK@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002702 797515.HMPREF9103_01659 1.3e-148 532.3 Lactobacillaceae proB GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPG6@1239,3F4E1@33958,4HA9B@91061,COG0263@1,COG0263@2 NA|NA|NA F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate gnl|extdb|FAM1079-i1-1.1_002715 797515.HMPREF9103_00602 0.0 1091.3 Lactobacillaceae rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3U9@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay gnl|extdb|FAM1079-i1-1.1_002716 908339.HMPREF9265_0827 3e-24 119.4 Lactobacillaceae Bacteria 1VXFK@1239,3FBB5@33958,4HX6X@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat gnl|extdb|FAM1079-i1-1.1_002717 797515.HMPREF9103_00599 2.7e-224 784.3 Lactobacillaceae tuf ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPKC@1239,3F3ZP@33958,4HAEH@91061,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis gnl|extdb|FAM1079-i1-1.1_002718 797515.HMPREF9103_00598 2e-218 765.0 Lactobacillaceae tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 1TQQ8@1239,3F40B@33958,4H9Q8@91061,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase gnl|extdb|FAM1079-i1-1.1_002719 797515.HMPREF9103_00597 1.5e-233 815.1 Lactobacillaceae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1TQ00@1239,3F41K@33958,4H9U4@91061,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP gnl|extdb|FAM1079-i1-1.1_002720 797515.HMPREF9103_00596 4.7e-108 397.1 Lactobacillaceae engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1TSPW@1239,3F44G@33958,4HBXZ@91061,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation gnl|extdb|FAM1079-i1-1.1_002721 797515.HMPREF9103_00595 4.5e-48 196.8 Lactobacillaceae MA20_27270 Bacteria 1VIQA@1239,3F6WJ@33958,4HM6C@91061,COG1694@1,COG1694@2 NA|NA|NA S mazG nucleotide pyrophosphohydrolase gnl|extdb|FAM1079-i1-1.1_002722 797515.HMPREF9103_00594 1.2e-246 858.6 Lactobacillaceae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1TP3X@1239,3F46X@33958,4HA1E@91061,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily gnl|extdb|FAM1079-i1-1.1_002723 1423743.JCM14108_610 7.6e-250 869.4 Lactobacillaceae argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TNZ6@1239,3F4PF@33958,4HB24@91061,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase gnl|extdb|FAM1079-i1-1.1_002724 797515.HMPREF9103_00590 1.4e-265 921.8 Lactobacillaceae glnPH2 ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease gnl|extdb|FAM1079-i1-1.1_002725 797515.HMPREF9103_00589 4e-136 490.7 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein gnl|extdb|FAM1079-i1-1.1_002726 1423743.JCM14108_606 0.0 1144.8 Lactobacillaceae uvrC ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP4B@1239,3F3MY@33958,4H9QH@91061,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gnl|extdb|FAM1079-i1-1.1_002729 797515.HMPREF9103_03169 8.4e-165 586.3 Lactobacillaceae mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02385 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family gnl|extdb|FAM1079-i1-1.1_002730 797515.HMPREF9103_03168 3.1e-220 770.8 Lactobacillaceae metC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine gnl|extdb|FAM1079-i1-1.1_002731 797515.HMPREF9103_03167 8.1e-94 349.7 Lactobacillaceae cysE 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR42@1239,3F63E@33958,4HAKS@91061,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) gnl|extdb|FAM1079-i1-1.1_002732 1136177.KCA1_2915 7e-243 846.3 Lactobacillaceae uxaC 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRI0@1239,3F4QN@33958,4HCGI@91061,COG1904@1,COG1904@2 NA|NA|NA G glucuronate isomerase gnl|extdb|FAM1079-i1-1.1_002733 1423816.BACQ01000031_gene1180 2.7e-37 161.4 Lactobacillaceae Bacteria 1U7QX@1239,29Q9K@1,30B8P@2,3FA19@33958,4IHN7@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002734 1423734.JCM14202_2313 2.6e-275 954.1 Lactobacillaceae uxuT ko:K03292,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.5 Bacteria 1U037@1239,3F4MV@33958,4HBZK@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein gnl|extdb|FAM1079-i1-1.1_002735 797515.HMPREF9103_03166 2.9e-248 864.0 Lactobacillaceae icd GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Bacteria 1UHPE@1239,3F4G4@33958,4H9US@91061,COG0538@1,COG0538@2 NA|NA|NA C Isocitrate/isopropylmalate dehydrogenase gnl|extdb|FAM1079-i1-1.1_002736 797515.HMPREF9103_03165 3.8e-212 743.8 Lactobacillaceae prpC GO:0003674,GO:0003824,GO:0004108,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.1,2.3.3.5 ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351,R00931 RC00004,RC00067,RC00406,RC02827 br01601,ko00000,ko00001,ko00002,ko01000 iECED1_1282.ECED1_0365,iECIAI1_1343.ECIAI1_0334,iECIAI39_1322.ECIAI39_0347,iECP_1309.ECP_0408,iECSF_1327.ECSF_0308,iEcE24377_1341.EcE24377A_0357,iJN678.gltA,iJN746.PP_2335,iLF82_1304.LF82_1740,iNRG857_1313.NRG857_01630 Bacteria 1TPPS@1239,3F4XX@33958,4H9YE@91061,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain gnl|extdb|FAM1079-i1-1.1_002737 797515.HMPREF9103_03164 0.0 1722.2 Lactobacillaceae acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06730 Bacteria 1VTMM@1239,3F4ZI@33958,4HB5N@91061,COG1048@1,COG1048@2 NA|NA|NA C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate gnl|extdb|FAM1079-i1-1.1_002738 797515.HMPREF9103_03163 1.6e-55 222.6 Lactobacillaceae mcbG Bacteria 1VBK8@1239,3F61B@33958,4HM5U@91061,COG1357@1,COG1357@2 NA|NA|NA S Pentapeptide repeats (8 copies) gnl|extdb|FAM1079-i1-1.1_002739 797515.HMPREF9103_03162 9.2e-141 506.1 Lactobacillaceae Bacteria 1TSCT@1239,3F5RK@33958,4HD4Z@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Oxidoreductase, short chain dehydrogenase reductase family protein gnl|extdb|FAM1079-i1-1.1_002741 701521.PECL_626 2.6e-39 172.2 Lactobacillaceae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1UI5M@1239,3F4B0@33958,4ISEJ@91061,COG2911@1,COG2911@2 NA|NA|NA N Cell shape-determining protein MreB gnl|extdb|FAM1079-i1-1.1_002742 797515.HMPREF9103_01708 1.7e-290 1004.6 Lactobacillaceae 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1TR6K@1239,3FBGJ@33958,4IQBA@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein gnl|extdb|FAM1079-i1-1.1_002743 797515.HMPREF9103_01707 8.3e-282 975.7 Lactobacillaceae 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1VSNK@1239,3F4VP@33958,4HU8G@91061,COG0438@1,COG0438@2 NA|NA|NA M Poly(Glycerol-phosphate) alpha-glucosyltransferase gnl|extdb|FAM1079-i1-1.1_002744 797515.HMPREF9103_01706 1.9e-23 114.4 Lactobacillaceae Bacteria 1U6R5@1239,2C19V@1,30AIR@2,3F8CF@33958,4IGIG@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002745 797515.HMPREF9103_01705 5.7e-97 360.1 Lactobacillaceae wecD3 Bacteria 1V6TX@1239,3FBED@33958,4HJZZ@91061,COG0454@1,COG0456@2 NA|NA|NA K (GNAT) family gnl|extdb|FAM1079-i1-1.1_002747 797515.HMPREF9103_01702 1.2e-182 646.4 Lactobacillaceae Bacteria 1U7HT@1239,29Q52@1,30B3Y@2,3F9QH@33958,4IHEF@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002748 797515.HMPREF9103_01701 6.7e-215 753.1 Lactobacillaceae atoB 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TP07@1239,3F3Q5@33958,4H9RJ@91061,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family gnl|extdb|FAM1079-i1-1.1_002752 797515.HMPREF9103_02060 1.2e-112 412.5 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein gnl|extdb|FAM1079-i1-1.1_002754 797515.HMPREF9103_02057 3.2e-92 344.4 Lactobacillaceae apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 1V1BV@1239,3F4DB@33958,4HFUA@91061,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis gnl|extdb|FAM1079-i1-1.1_002755 797515.HMPREF9103_02056 0.0 1506.1 Lactobacillaceae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXE@1239,3F42C@33958,4H9UP@91061,COG0608@1,COG0608@2 NA|NA|NA L Single-stranded-DNA-specific exonuclease RecJ gnl|extdb|FAM1079-i1-1.1_002756 797515.HMPREF9103_02055 1e-48 199.5 Lactobacillaceae yrvD ko:K08992 ko00000 Bacteria 1VGMG@1239,3F73I@33958,4HQ29@91061,COG5416@1,COG5416@2 NA|NA|NA S Pfam:DUF1049 gnl|extdb|FAM1079-i1-1.1_002757 797515.HMPREF9103_02054 5.2e-178 630.2 Lactobacillaceae rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TRGP@1239,3F4F1@33958,4HABM@91061,COG1234@1,COG1234@2 NA|NA|NA J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA gnl|extdb|FAM1079-i1-1.1_002759 797515.HMPREF9103_02052 1.9e-98 365.5 Lactobacillaceae Bacteria 1W1U2@1239,2C356@1,2ZK2C@2,3F6RB@33958,4I1Z8@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002760 797515.HMPREF9103_00584 0.0 1279.6 Lactobacillaceae oatA Bacteria 1TPTG@1239,3F3WT@33958,4HB7R@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase gnl|extdb|FAM1079-i1-1.1_002761 797515.HMPREF9103_00585 2.1e-246 857.8 Lactobacillaceae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1TPX7@1239,3F4ZA@33958,4H9P8@91061,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control gnl|extdb|FAM1079-i1-1.1_002751 797515.HMPREF9103_02061 1.8e-65 255.0 Lactobacillaceae yugI 5.3.1.9 ko:K01810,ko:K02945,ko:K07570,ko:K07571,ko:K19142 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko03010,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map03010 M00001,M00004,M00114,M00178 R02739,R02740,R03321 RC00376,RC00563 br01610,ko00000,ko00001,ko00002,ko01000,ko02048,ko03011,ko04147 Bacteria 1VASQ@1239,3F6AN@33958,4HKSW@91061,COG1098@1,COG1098@2 NA|NA|NA J general stress protein gnl|extdb|FAM1079-i1-1.1_002758 797515.HMPREF9103_02053 2.3e-44 184.5 Lactobacillaceae Bacteria 1U6FA@1239,29PD4@1,30ABB@2,3F7SF@33958,4IG75@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002762 1423743.JCM14108_1885 3.1e-233 814.3 Lactobacillaceae aldA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004029,GO:0004777,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0008911,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019299,GO:0019301,GO:0019317,GO:0019318,GO:0019320,GO:0019752,GO:0022607,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042354,GO:0042355,GO:0042802,GO:0043436,GO:0043648,GO:0043649,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0048037,GO:0050569,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 iAF1260.b1415,iBWG_1329.BWG_1242,iECDH10B_1368.ECDH10B_1541,iECDH1ME8569_1439.ECDH1ME8569_1358,iEcDH1_1363.EcDH1_2230,iJO1366.b1415,iJR904.b1415,iY75_1357.Y75_RS07435 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family gnl|extdb|FAM1079-i1-1.1_002763 1122146.AUHP01000011_gene254 2.4e-08 64.3 Lactobacillaceae Bacteria 1U6Z9@1239,2DKT3@1,30AQA@2,3F8RG@33958,4IGTI@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002765 525318.HMPREF0497_2839 8.1e-117 427.2 Lactobacillaceae ko:K15051 ko00000 Bacteria 1VD0S@1239,2DZEC@1,32V8J@2,3F4K6@33958,4HN7Y@91061 NA|NA|NA S DNA/RNA non-specific endonuclease gnl|extdb|FAM1079-i1-1.1_002766 1071400.LBUCD034_1999 7.7e-58 231.5 Lactobacillaceae Bacteria 1U5KD@1239,29XME@1,309S1@2,3F64M@33958,4IFB6@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002767 1071400.LBUCD034_0125 3.4e-127 461.5 Lactobacillaceae Bacteria 1UYD7@1239,3F5NI@33958,4HHUD@91061,COG4886@1,COG4886@2 NA|NA|NA NU Mycoplasma protein of unknown function, DUF285 gnl|extdb|FAM1079-i1-1.1_002769 203123.OEOE_1494 2.2e-09 66.6 Leuconostocaceae ko:K07497 ko00000 Bacteria 1U3DM@1239,4AXMR@81850,4ID5Z@91061,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_002770 324831.LGAS_0622 3.5e-14 84.3 Lactobacillaceae Bacteria 1U6FT@1239,29PDN@1,30ABU@2,3F7TJ@33958,4IG7S@91061 NA|NA|NA S Protein of unknown function (DUF2577) gnl|extdb|FAM1079-i1-1.1_002771 1302286.BAOT01000008_gene612 1.7e-78 299.7 Lactobacillaceae yqbQ Bacteria 1TYY9@1239,3FBQX@33958,4IS15@91061,COG4193@1,COG4193@2 NA|NA|NA G PFAM Phage late control gene D protein (GPD) gnl|extdb|FAM1079-i1-1.1_002772 1423734.JCM14202_3044 2e-36 159.5 Lactobacillaceae ko:K02030,ko:K16291 M00236 ko00000,ko00002,ko01002,ko01011,ko02000 3.A.1.3 Bacteria 1V1BA@1239,3F6QJ@33958,4HFRJ@91061,COG1652@1,COG1652@2 NA|NA|NA S protein containing LysM domain gnl|extdb|FAM1079-i1-1.1_002773 1302286.BAOT01000008_gene610 2.3e-110 407.1 Lactobacillaceae Bacteria 1TRVJ@1239,3FC1T@33958,4HC3P@91061,COG5283@1,COG5283@2,COG5412@1,COG5412@2 NA|NA|NA S phage tail tape measure protein gnl|extdb|FAM1079-i1-1.1_002774 1423734.JCM14202_3048 7.9e-33 147.1 Lactobacillaceae xkdN Bacteria 1VCQF@1239,2E0UT@1,32WC6@2,3F7B9@33958,4HQZX@91061 NA|NA|NA S Phage XkdN-like tail assembly chaperone protein, TAC gnl|extdb|FAM1079-i1-1.1_002775 139871.A9D9V4_9VIRU 1.7e-55 222.2 Viruses Viruses 4QAWH@10239 NA|NA|NA S Protein of unknown function (DUF2001) gnl|extdb|FAM1079-i1-1.1_002776 1423734.JCM14202_3050 1.2e-125 456.8 Lactobacillaceae xkdK Bacteria 1TP1Y@1239,28IGV@1,2Z8I6@2,3F4FU@33958,4HD7A@91061 NA|NA|NA S Phage tail sheath C-terminal domain gnl|extdb|FAM1079-i1-1.1_002778 1302286.BAOT01000008_gene606 6.9e-34 150.2 Lactobacillaceae Bacteria 1U64Z@1239,2ANTG@1,31DTR@2,3F727@33958,4IFUQ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002779 1302286.BAOT01000008_gene605 7.1e-31 140.2 Bacilli Bacteria 1VH0P@1239,2DQBP@1,335UA@2,4IRV0@91061 NA|NA|NA S Bacteriophage HK97-gp10, putative tail-component gnl|extdb|FAM1079-i1-1.1_002781 1423734.JCM14202_3054 1.3e-34 152.5 Lactobacillaceae Bacteria 1VYK5@1239,2FH0J@1,348VN@2,3F7P1@33958,4HZB4@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002782 877415.JNJQ01000035_gene1182 2.5e-09 68.9 Firmicutes prtS 3.2.1.4,3.2.1.81,3.4.21.110,3.4.21.96 ko:K01179,ko:K01219,ko:K01361,ko:K08652,ko:K17734 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000,ko01002,ko03110 GH5,GH9 Bacteria 1TPH1@1239,COG1404@1,COG1404@2,COG5279@1,COG5279@2,COG5492@1,COG5492@2 NA|NA|NA O Belongs to the peptidase S8 family gnl|extdb|FAM1079-i1-1.1_002783 203123.OEOE_1494 4.9e-09 65.5 Leuconostocaceae ko:K07497 ko00000 Bacteria 1U3DM@1239,4AXMR@81850,4ID5Z@91061,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_002780 1423734.JCM14202_3053 1.5e-45 188.7 Lactobacillaceae Bacteria 1W4S3@1239,28U7C@1,2ZGD0@2,3F73Y@33958,4I0YU@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002784 797515.HMPREF9103_02891 9e-71 272.7 Lactobacillaceae pdxH ko:K07006 ko00000 Bacteria 1V4U5@1239,3F6E3@33958,4HXTU@91061,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase gnl|extdb|FAM1079-i1-1.1_002785 1423780.LOT_0790 2.3e-46 192.2 Lactobacillaceae Bacteria 1VAQZ@1239,3FBPB@33958,4HJFH@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) gnl|extdb|FAM1079-i1-1.1_002786 797515.HMPREF9103_02894 2.3e-136 491.5 Lactobacillaceae wzb 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V6Q5@1239,3F5X1@33958,4HJKY@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family gnl|extdb|FAM1079-i1-1.1_002787 797515.HMPREF9103_02895 1.8e-49 201.4 Lactobacillaceae ycnE GO:0003674,GO:0003824 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1VG4T@1239,3F7H6@33958,4HPNQ@91061,COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase gnl|extdb|FAM1079-i1-1.1_002788 525318.HMPREF0497_2141 9.4e-232 809.3 Lactobacillaceae loxD 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 1TPBC@1239,3F4AD@33958,4H9UU@91061,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain gnl|extdb|FAM1079-i1-1.1_002789 797515.HMPREF9103_02898 5.8e-186 656.8 Lactobacillaceae Bacteria 1UHSE@1239,3F5YK@33958,4HEGH@91061,COG1503@1,COG1503@2 NA|NA|NA J translation release factor activity gnl|extdb|FAM1079-i1-1.1_002790 797515.HMPREF9103_02899 1.3e-142 512.3 Lactobacillaceae 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSNU@1239,3F3JH@33958,4H9TY@91061,COG1085@1,COG1085@2 NA|NA|NA C Domain of unknown function (DUF4931) gnl|extdb|FAM1079-i1-1.1_002791 797515.HMPREF9103_02901 1.4e-186 658.7 Lactobacillaceae pdxB Bacteria 1TSDK@1239,3F4DF@33958,4HAW5@91061,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain gnl|extdb|FAM1079-i1-1.1_002792 797515.HMPREF9103_02902 0.0 1162.5 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family gnl|extdb|FAM1079-i1-1.1_002793 797515.HMPREF9103_02602 6.3e-162 576.6 Lactobacillaceae licD ko:K07271 ko00000,ko01000 Bacteria 1V75G@1239,3FBFT@33958,4IQ5G@91061,COG3475@1,COG3475@2 NA|NA|NA M LicD family gnl|extdb|FAM1079-i1-1.1_002794 797515.HMPREF9103_02601 4.6e-202 710.3 Lactobacillaceae xerS GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K04763 ko00000,ko03036 Bacteria 1URNQ@1239,3FBHV@33958,4HEPI@91061,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family gnl|extdb|FAM1079-i1-1.1_002795 1423780.LOT_0323 1.4e-153 549.3 Lactobacillaceae mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPUT@1239,3FCD0@33958,4H9UM@91061,COG1194@1,COG1194@2 NA|NA|NA L A G-specific adenine glycosylase gnl|extdb|FAM1079-i1-1.1_002796 797515.HMPREF9103_02597 4e-141 507.3 Lactobacillaceae Bacteria 1V1FZ@1239,3F5GS@33958,4HEFT@91061,COG5036@1,COG5036@2 NA|NA|NA P VTC domain gnl|extdb|FAM1079-i1-1.1_002797 797515.HMPREF9103_02596 5.6e-105 387.1 Lactobacillaceae XK27_05505 Bacteria 1V1GI@1239,3F5YD@33958,4HGIX@91061,COG1285@1,COG1285@2 NA|NA|NA S Domain of unknown function (DUF4956) gnl|extdb|FAM1079-i1-1.1_002798 797515.HMPREF9103_02595 0.0 1248.4 Lactobacillaceae cotH Bacteria 1UV97@1239,3F5PU@33958,4IF5J@91061,COG5337@1,COG5337@2 NA|NA|NA M CotH kinase protein gnl|extdb|FAM1079-i1-1.1_002799 797515.HMPREF9103_02594 5e-204 716.8 Lactobacillaceae gldA 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 Bacteria 1TQFU@1239,3F4E4@33958,4HC8K@91061,COG0371@1,COG0371@2 NA|NA|NA C dehydrogenase gnl|extdb|FAM1079-i1-1.1_002802 1423743.JCM14108_2890 2.4e-109 401.7 Lactobacillaceae Bacteria 1U5J5@1239,2DEMA@1,2ZNFB@2,3F62E@33958,4IF9X@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002803 1071400.LBUCD034_1573 4.1e-239 833.6 Lactobacillaceae Bacteria 1V4E8@1239,3F5UR@33958,4HMSZ@91061,COG4722@1,COG4722@2 NA|NA|NA S Phage tail protein gnl|extdb|FAM1079-i1-1.1_002804 1071400.LBUCD034_1574 0.0 3012.2 Lactobacillaceae 2.1.1.80,3.1.1.61 ko:K02057,ko:K07192,ko:K13924,ko:K15125,ko:K19303,ko:K21471 ko02020,ko02030,ko04910,ko05133,map02020,map02030,map04910,map05133 M00221,M00506 ko00000,ko00001,ko00002,ko00536,ko01000,ko01002,ko01011,ko02000,ko02022,ko02035,ko03036,ko04131,ko04147 3.A.1.2 Bacteria 1UZN8@1239,3F3T2@33958,4HGQG@91061,COG0419@1,COG0419@2,COG0791@1,COG0791@2,COG1196@1,COG1196@2,COG2268@1,COG2268@2,COG5283@1,COG5283@2 NA|NA|NA M Phage tail tape measure protein TP901 gnl|extdb|FAM1079-i1-1.1_002805 1071400.LBUCD034_1576 5.2e-60 236.9 Lactobacillaceae Bacteria 1UQAP@1239,2BREX@1,32KDR@2,3F6F5@33958,4IFGH@91061 NA|NA|NA S Phage tail assembly chaperone proteins, TAC gnl|extdb|FAM1079-i1-1.1_002806 797515.HMPREF9103_01184 6.9e-144 516.5 Lactobacillaceae Bacteria 1TSZZ@1239,3F49K@33958,4HB54@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase gnl|extdb|FAM1079-i1-1.1_002807 797515.HMPREF9103_01183 1.1e-118 432.6 Lactobacillaceae dck 2.7.1.74 ko:K00893 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F4MY@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase gnl|extdb|FAM1079-i1-1.1_002808 797515.HMPREF9103_01182 8.8e-147 526.2 Lactobacillaceae Bacteria 1V2CT@1239,28P7V@1,2ZC22@2,3F6CH@33958,4HG6A@91061 NA|NA|NA S Protein of unknown function gnl|extdb|FAM1079-i1-1.1_002809 797515.HMPREF9103_01181 1.3e-79 302.4 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VMC9@1239,3F6UZ@33958,4HYXY@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family gnl|extdb|FAM1079-i1-1.1_002810 797515.HMPREF9103_01180 1.3e-278 964.9 Lactobacillaceae pepV 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPEG@1239,3F3UV@33958,4HC14@91061,COG0624@1,COG0624@2 NA|NA|NA E dipeptidase PepV gnl|extdb|FAM1079-i1-1.1_002811 797515.HMPREF9103_01179 2.4e-150 538.1 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1TNZE@1239,3F480@33958,4HBZC@91061,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration gnl|extdb|FAM1079-i1-1.1_002812 797515.HMPREF9103_01178 4.9e-296 1023.1 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein gnl|extdb|FAM1079-i1-1.1_002814 1071400.LBUCD034_0125 1.5e-15 90.1 Lactobacillaceae Bacteria 1UYD7@1239,3F5NI@33958,4HHUD@91061,COG4886@1,COG4886@2 NA|NA|NA NU Mycoplasma protein of unknown function, DUF285 gnl|extdb|FAM1079-i1-1.1_002815 1423780.LOT_1072 9.5e-92 344.0 Lactobacillaceae Bacteria 1UWPY@1239,3F9DA@33958,4IH86@91061,COG4886@1,COG4886@2 NA|NA|NA S Leucine Rich repeats (2 copies) gnl|extdb|FAM1079-i1-1.1_002817 525318.HMPREF0497_0571 2.1e-189 668.3 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent gnl|extdb|FAM1079-i1-1.1_002818 797515.HMPREF9103_03158 1.6e-87 328.6 Lactobacillaceae luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1CH@1239,3F4W2@33958,4HFPR@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) gnl|extdb|FAM1079-i1-1.1_002819 797515.HMPREF9103_03157 0.0 1510.7 Lactobacillaceae metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Bacteria 1TP2H@1239,3F3VW@33958,4H9QC@91061,COG0620@1,COG0620@2 NA|NA|NA E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation gnl|extdb|FAM1079-i1-1.1_002820 525318.HMPREF0497_0568 2e-150 538.5 Lactobacillaceae metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297,ko:K21010 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0117,iSBO_1134.SBO_3961 Bacteria 1TQFE@1239,3F59R@33958,4HBVI@91061,COG0685@1,COG0685@2 NA|NA|NA C Methylenetetrahydrofolate reductase gnl|extdb|FAM1079-i1-1.1_002821 797515.HMPREF9103_03154 1.5e-141 508.8 Lactobacillaceae ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1U4VN@1239,3FBDK@33958,4IPPT@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins gnl|extdb|FAM1079-i1-1.1_002822 1114972.AUAW01000027_gene720 1.3e-08 64.3 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_002824 1423743.JCM14108_2892 1e-145 522.7 Lactobacillaceae Bacteria 1U5H6@1239,2AK8S@1,31AZ1@2,3F5XY@33958,4IF81@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002826 1071400.LBUCD034_1601 9.6e-21 105.1 Lactobacillaceae Bacteria 1UYND@1239,3FBNE@33958,4IRAQ@91061,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_002827 1423780.LOT_2218 2.2e-11 73.6 Lactobacillaceae tnp2PF3 Bacteria 1VXWA@1239,3F7AF@33958,4HXG3@91061,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain gnl|extdb|FAM1079-i1-1.1_002828 797515.HMPREF9103_00243 3.4e-74 284.3 Lactobacillaceae Bacteria 1UZW1@1239,3F7GN@33958,4HD5Y@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family gnl|extdb|FAM1079-i1-1.1_002829 797515.HMPREF9103_00241 1e-51 210.3 Lactobacillaceae Bacteria 1U683@1239,29P3U@1,30A5H@2,3F7A4@33958,4IFYU@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002831 797515.HMPREF9103_00237 7e-158 563.1 Lactobacillaceae Bacteria 1VDT8@1239,3FBY7@33958,4ISAW@91061,COG1834@1,COG1834@2 NA|NA|NA E Amidinotransferase gnl|extdb|FAM1079-i1-1.1_002833 218495.SUB0501 6.7e-87 327.8 Bacilli comA ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 Bacteria 1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2 NA|NA|NA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain gnl|extdb|FAM1079-i1-1.1_002834 1158607.UAU_03350 3.4e-14 85.1 Enterococcaceae Bacteria 1VYYY@1239,2FEWE@1,346V7@2,4B5CK@81852,4HZ2Y@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002840 797515.HMPREF9103_02047 1e-14 85.5 Bacteria WQ51_00220 ko:K07729 ko00000,ko03000 Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding gnl|extdb|FAM1079-i1-1.1_002842 797515.HMPREF9103_02628 0.0 1305.4 Lactobacillaceae ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F424@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein 1A gnl|extdb|FAM1079-i1-1.1_002843 797515.HMPREF9103_02627 3.2e-112 411.0 Lactobacillaceae recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03700 ko00000,ko03400 Bacteria 1V3S4@1239,3F4DG@33958,4HGZ7@91061,COG3331@1,COG3331@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation gnl|extdb|FAM1079-i1-1.1_002844 797515.HMPREF9103_02626 2.7e-108 397.9 Lactobacillaceae ypsA Bacteria 1V6SM@1239,3F4MR@33958,4HJGM@91061,COG4474@1,COG4474@2 NA|NA|NA S Belongs to the UPF0398 family gnl|extdb|FAM1079-i1-1.1_002845 797515.HMPREF9103_02625 8.7e-60 236.1 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1VEQ4@1239,3F6VZ@33958,4HNP1@91061,COG3599@1,COG3599@2 NA|NA|NA D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gnl|extdb|FAM1079-i1-1.1_002848 97137.C821_00704 5.3e-114 417.9 Lactobacillaceae xkdT Bacteria 1TQZU@1239,3FBAC@33958,4HG66@91061,COG3299@1,COG3299@2 NA|NA|NA S Baseplate J-like protein gnl|extdb|FAM1079-i1-1.1_002849 363555.Q20DB9_9CAUD 4.1e-26 124.8 Viruses Viruses 4QAYF@10239 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2313) gnl|extdb|FAM1079-i1-1.1_002847 1302286.BAOT01000008_gene614 4.4e-29 134.4 Lactobacillaceae Bacteria 1V9Z3@1239,3F7VE@33958,4HQ0S@91061,COG3628@1,COG3628@2 NA|NA|NA S Protein of unknown function (DUF2634) gnl|extdb|FAM1079-i1-1.1_002852 797515.HMPREF9103_01120 3.9e-116 424.1 Lactobacillaceae Bacteria 1U5ZI@1239,29P1A@1,309ZG@2,3F6RH@33958,4IFNJ@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002853 797515.HMPREF9103_01119 2.4e-239 834.3 Lactobacillaceae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 1TPGN@1239,3F48J@33958,4H9YV@91061,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) gnl|extdb|FAM1079-i1-1.1_002854 797515.HMPREF9103_02460 5.9e-85 320.5 Lactobacillaceae Bacteria 1U5M2@1239,29EK4@1,301I2@2,3F668@33958,4IFBX@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002855 1423743.JCM14108_2897 7.2e-34 149.4 Lactobacillaceae Bacteria 1W39V@1239,2C0XI@1,2ZJRZ@2,3F76K@33958,4I12U@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002856 797515.HMPREF9103_02458 7.1e-155 553.1 Lactobacillaceae 3.2.1.17 ko:K01185 ko00000,ko01000 Bacteria 1V3SH@1239,3F6ZF@33958,4HNR1@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 gnl|extdb|FAM1079-i1-1.1_002857 1071400.LBUCD034_1565 7.5e-68 263.1 Lactobacillaceae Bacteria 1U54S@1239,2CHVQ@1,309HZ@2,3F4NN@33958,4IEVX@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002858 575594.ACOH01000016_gene1565 1e-10 71.2 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_002859 797515.HMPREF9103_01682 2.2e-162 578.2 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U79A@1239,3F3RK@33958,4HAZS@91061,COG3001@1,COG3001@2 NA|NA|NA G Phosphotransferase enzyme family gnl|extdb|FAM1079-i1-1.1_002860 797515.HMPREF9103_01684 3.2e-164 584.3 Lactobacillaceae yicL Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family gnl|extdb|FAM1079-i1-1.1_002861 797515.HMPREF9103_01685 1.1e-40 172.6 Lactobacillaceae Bacteria 1U6GV@1239,3F7W5@33958,4IG91@91061,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) gnl|extdb|FAM1079-i1-1.1_002863 1054213.HMPREF9946_05337 2e-156 558.5 Alphaproteobacteria Bacteria 1N22J@1224,2UGBX@28211,COG5655@1,COG5655@2 NA|NA|NA L Replication protein gnl|extdb|FAM1079-i1-1.1_002864 797515.HMPREF9103_02990 2.1e-82 311.6 Lactobacillaceae Bacteria 1V6P0@1239,3F63I@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE gnl|extdb|FAM1079-i1-1.1_002865 797515.HMPREF9103_02991 1.4e-136 492.3 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter gnl|extdb|FAM1079-i1-1.1_002866 525318.HMPREF0497_1965 6.7e-103 380.2 Lactobacillaceae sirR ko:K03709 ko00000,ko03000 Bacteria 1V3IS@1239,3F405@33958,4HH06@91061,COG1321@1,COG1321@2 NA|NA|NA K iron dependent repressor gnl|extdb|FAM1079-i1-1.1_002868 1234679.BN424_1668 3e-115 422.2 Carnobacteriaceae Bacteria 1TPH7@1239,27H8U@186828,4HB3I@91061,COG3385@1,COG3385@2 NA|NA|NA L Transposase DDE domain group 1 gnl|extdb|FAM1079-i1-1.1_002869 797515.HMPREF9103_01494 2.2e-82 312.0 Lactobacillaceae Bacteria 1UFZH@1239,29V33@1,30GGE@2,3F5BQ@33958,4IF1H@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002870 797515.HMPREF9103_01493 4e-64 250.8 Lactobacillaceae Bacteria 1U68I@1239,29P7Q@1,30A5T@2,3F7AY@33958,4IFZD@91061 NA|NA|NA gnl|extdb|FAM1079-i1-1.1_002872 1410631.JHWZ01000032_gene1176 5.2e-171 607.4 unclassified Lachnospiraceae Bacteria 1TPFS@1239,249JM@186801,27JF9@186928,COG3039@1,COG3039@2 NA|NA|NA L Transposase domain (DUF772) gnl|extdb|FAM1079-i1-1.1_002873 60520.HR47_01150 2.3e-168 598.2 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_002874 334390.LAF_0673 6.3e-118 430.6 Lactobacillaceae Bacteria 1UHY6@1239,3FBS3@33958,4ISAK@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein gnl|extdb|FAM1079-i1-1.1_002876 1114972.AUAW01000027_gene720 1.3e-08 64.3 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region gnl|extdb|FAM1079-i1-1.1_002878 1071400.LBUCD034_1601 9.6e-21 105.1 Lactobacillaceae Bacteria 1UYND@1239,3FBNE@33958,4IRAQ@91061,COG4584@1,COG4584@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_002881 203123.OEOE_1495 5.7e-39 166.4 Leuconostocaceae ko:K07483 ko00000 Bacteria 1UA5J@1239,4AY88@81850,4IDAI@91061,COG2963@1,COG2963@2 NA|NA|NA L Transposase gnl|extdb|FAM1079-i1-1.1_002880 203123.OEOE_1494 4.5e-37 160.2 Leuconostocaceae ko:K07497 ko00000 Bacteria 1U3DM@1239,4AXMR@81850,4ID5Z@91061,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain gnl|extdb|FAM1079-i1-1.1_002888 1423743.JCM14108_2814 6.9e-17 92.0 Lactobacillaceae ko:K07483 ko00000 Bacteria 1U6JB@1239,3F80X@33958,4IGBV@91061,COG2963@1,COG2963@2 NA|NA|NA L CENP-B N-terminal DNA-binding domain # 2602 queries scanned # Total time (seconds): 4078.09278584 # Rate: 0.64 q/s